The role of PI3K/AKT, MAPK/ERK and NFκβ signalling in the maintenance of human embryonic stem cell pluripotency and viability highlighted by transcriptional profiling and functional analysis

Human Molecular Genetics

Volumn 15, Issue 11, 2006, Pages 1894-1913

  Armstrong, Lyle ^a   Hughes, Owen ^a   Yung, Sun ^a   Hyslop, Louise ^a   Stewart, Rebecca ^a   Wappler, Ilka ^a   Peters, Heiko ^a   Walter, Theresia ^a   Stojkovic, Petra ^a,b   Evans, Jerome ^a   Stojkovic, Miodrag ^a,b   Lako, Majlinda ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

^b CENTRO DE INVESTIGACIÓN PRÍNCIPE FELIPE   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 MORPHOLINO 8 PHENYLCHROMONE; ANTIBODY; ENZYME INHIBITOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR;

ANIMAL CELL; ARTICLE; BIOINFORMATICS; CELL DIFFERENTIATION; CELL LINE; CELL STRUCTURE; CELL VIABILITY; CONTROLLED STUDY; DEVELOPMENTAL STAGE; DOWN REGULATION; EMBRYO; EMBRYO DEVELOPMENT; EMBRYONIC STEM CELL; FLOW CYTOMETRY; FUNCTIONAL ASSESSMENT; GENE EXPRESSION PROFILING; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; ISOLATION PROCEDURE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

1-PHOSPHATIDYLINOSITOL 3-KINASE; CELL SURVIVAL; COMPUTATIONAL BIOLOGY; EMBRYO; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FEMALE; HUMANS; KARYOTYPING; MALE; MAP KINASE SIGNALING SYSTEM; MODELS, BIOLOGICAL; NF-KAPPA B; SIGNAL TRANSDUCTION; STEM CELLS; TRANSCRIPTION, GENETIC;

EID: 33744758028     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddl112     Document Type: Article

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