ELABELA Is an Endogenous Growth Factor that Sustains hESC Self-Renewal via the PI3K/AKT Pathway

Cell Stem Cell

Volumn 17, Issue 4, 2015, Pages 435-447

  Ho, Lena ^a   Tan, Shawn Y X ^a   Wee, Sheena ^b   Wu, Yixuan ^a   Tan, Sam J C ^a   Ramakrishna, Navin B ^a   Chng, Serene C ^a   Nama, Srikanth ^a   Szczerbinska, Iwona ^c   Chan, Yun Shen ^c   Avery, Stuart ^a   Tsuneyoshi, Norihiro ^a   Ng, Huck Hui ^c   Gunaratne, Jayantha ^b   Dunn, N Ray ^a   Reversade, Bruno ^a,b  

^a INSTITUTE OF MEDICAL BIOLOGY   (Singapore)

^b INSTITUTE OF MOLECULAR AND CELL BIOLOGY   (Singapore)

^c GENOME INSTITUTE OF SINGAPORE   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

CELL SURFACE RECEPTOR; ELABELA HORMONE; INSULIN; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; NEUTRALIZING ANTIBODY; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; RECOMBINANT GROWTH FACTOR; RECOMBINANT HORMONE; SHORT HAIRPIN RNA; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; APLNR PROTEIN, HUMAN; ELA PEPTIDE, HUMAN; G PROTEIN COUPLED RECEPTOR; PEPTIDE HORMONE; SIGNAL PEPTIDE; SMALL INTERFERING RNA;

ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; CELL CYCLE PROGRESSION; CELL LINEAGE; CELL PROLIFERATION; CELL SURFACE; CELL SURVIVAL; CONTROLLED STUDY; CRISPR CAS SYSTEM; EMBRYO; ENDODERM; ENZYME ACTIVATION; GENE DELETION; HUMAN; HUMAN CELL; HUMAN EMBRYO; HUMAN EMBRYONIC STEM CELL; MITOSIS INHIBITION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PARACRINE SIGNALING; PHOSPHOPROTEOMICS; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEOMICS; STEM CELL SELF-RENEWAL; TRANSCRIPTOMICS; TRANSLATION INITIATION; CELL DIFFERENTIATION; CELL LINE; CELL SELF-RENEWAL; CYTOLOGY; GENE EXPRESSION PROFILING; METABOLISM; SECRETION (PROCESS); SIGNAL TRANSDUCTION;

ANTIBODIES, NEUTRALIZING; CELL DIFFERENTIATION; CELL LINE; CELL SELF RENEWAL; ENDODERM; GENE EXPRESSION PROFILING; HUMAN EMBRYONIC STEM CELLS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; PARACRINE COMMUNICATION; PEPTIDE HORMONES; PHOSPHATIDYLINOSITOL 3-KINASES; PROTEOMICS; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTORS, G-PROTEIN-COUPLED; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION;

EID: 84952628647     PISSN: 19345909     EISSN: 18759777     Source Type: Journal    
DOI: 10.1016/j.stem.2015.08.010     Document Type: Article

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