Regulation of protein homeostasis in neurodegenerative diseases: The role of coding and non-coding genes

Cellular and Molecular Life Sciences

Volumn 72, Issue 21, 2015, Pages 4027-4047

  Sin, Olga ^a,b   Nollen, Ellen A A ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^b UNIVERSITY OF PORTO   (Portugal)

Author keywords

Aggresome; Alzheimer's disease; C. elegans; Chaperone; Genetic modifiers; Huntington's disease; iPOD; JunQ; miRNA; Neurodegeneration; Non coding RNA; Parkinson's disease; Protein aggregation; Protein homeostasis; Protein quality control; Proteostasis; Proteotoxicity; tRNA

Indexed keywords

ALPHA SYNUCLEIN; BETA SECRETASE; MICRORNA; POLYGLUTAMINE; SMALL NUCLEAR RNA; SURVIVAL MOTOR NEURON PROTEIN; TRANSFER RNA; UNTRANSLATED RNA; PROTEIN;

ALZHEIMER DISEASE; AMYLOID PLAQUE; DEGENERATIVE DISEASE; GENE; HUMAN; HUNTINGTON CHOREA; LEWY BODY; NEUROFIBRILLARY TANGLE; NEUROPROTECTION; NONHUMAN; PARKINSON DISEASE; PROTEIN AGGREGATION; PROTEIN COMPARTMENTALIZATION; PROTEIN DEGRADATION; PROTEIN FOLDING; PROTEIN HOMEOSTASIS; PROTEIN MISFOLDING; PROTEOMICS; REVIEW; SPINOCEREBELLAR DEGENERATION; SPLICING DEFECT; ANIMAL; CAENORHABDITIS ELEGANS; CHEMISTRY; DISEASE MODEL; DROSOPHILA; GENETICS; HOMEOSTASIS; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; PROTEIN CONFORMATION; SACCHAROMYCES CEREVISIAE;

ALZHEIMER DISEASE; ANIMALS; CAENORHABDITIS ELEGANS; DISEASE MODELS, ANIMAL; DROSOPHILA; HOMEOSTASIS; HUMANS; NEURODEGENERATIVE DISEASES; PARKINSON DISEASE; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEINS; RNA, UNTRANSLATED; SACCHAROMYCES CEREVISIAE;

EID: 84944175522     PISSN: 1420682X     EISSN: 14209071     Source Type: Journal    
DOI: 10.1007/s00018-015-1985-0     Document Type: Review

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