Impairment of the tRNA-splicing endonuclease subunit 54 (tsen54) gene causes neurological abnormalities and larval death in zebrafish models of pontocerebellar hypoplasia

Human Molecular Genetics

Volumn 20, Issue 8, 2011, Pages 1574-1584

  Kasher, Paul R ^a   Namavar, Yasmin ^a   van Tijn, Paula ^b,d   Fluiter, Kees ^a   Sizarov, Aleksander ^a   Kamermans, Maarten ^b   Grierson, Andrew J ^c   Zivkovic, Danica ^d   Baas, Frank ^a  

^a ACADEMIC MEDICAL CENTER   (Netherlands)

^b NETHERLANDS INSTITUTE FOR NEUROSCIENCE   (Netherlands)

^c UNIVERSITY OF SHEFFIELD   (United Kingdom)

^d UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE TRANSFER RNA LIGASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN DEVELOPMENT; CELL DEATH; CONTROLLED STUDY; DEGENERATIVE DISEASE; EMBRYO; FETUS; GENE; GENE EXPRESSION; GENE MUTATION; GENE STRUCTURE; HUMAN; HUMAN TISSUE; LARVAL DEVELOPMENT; LOSS OF FUNCTION MUTATION; NONHUMAN; PONTOCEREBELLAR HYPOPLASIA; PRIORITY JOURNAL; RNA TRANSLATION; STOP CODON; TRNA SPLICING ENDONUCLEASE SUBUNIT 54 GENE; ZEBRA FISH;

ANIMALS; ARGININE-TRNA LIGASE; BASE SEQUENCE; BODY PATTERNING; BRAIN; CELL DEATH; ENDORIBONUCLEASES; FIBROBLAST GROWTH FACTORS; GENE SILENCING; HUMANS; IN SITU HYBRIDIZATION; LARVA; OLIVOPONTOCEREBELLAR ATROPHIES; OTX TRANSCRIPTION FACTORS; PHENOTYPE; TRANSCRIPTION, GENETIC; ZEBRAFISH; ZEBRAFISH PROTEINS;

DANIO RERIO;

EID: 79953110006     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddr034     Document Type: Article

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