CLP1 links tRNA metabolism to progressive motor-neuron loss

Nature

Volumn 495, Issue 7442, 2013, Pages 474-480

  Hanada, Toshikatsu ^a   Weitzer, Stefan ^a   Mair, Barbara ^a   Bernreuther, Christian ^b   Wainger, Brian J ^c,d   Ichida, Justin ^e   Hanada, Reiko ^a   Orthofer, Michael ^a   Cronin, Shane J ^c   Komnenovic, Vukoslav ^a   Minis, Adi ^f   Sato, Fuminori ^g   Mimata, Hiromitsu ^g   Yoshimura, Akihiko ^h   Tamir, Ido ⁱ   Rainer, Johannes ^j   Kofler, Reinhard ^j   Yaron, Avraham ^f   Eggan, Kevin C ^e   Woolf, Clifford J ^c,k   Glatzel, Markus ^b   Herbst, Ruth ^l   Martinez, Javier ^a   Penninger, Josef M ^a   more..

^a ERICH SCHMID INSTITUTE OF MATERIALS SCIENCE   (Austria)

^b UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^c BOSTON CHILDREN S HOSPITAL   (United States)

^d MASSACHUSETTS GENERAL HOSPITAL   (United States)

^e HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^f WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^g OITA UNIVERSITY   (Japan)

^h KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

ⁱ CampusScience Support FacilitiesGmbH   (Austria)

^j INNSBRUCK MEDICAL UNIVERSITY   (Austria)

^k HARVARD MEDICAL SCHOOL   (United States)

^l Medical University of Vienna   (Austria)

more..

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN CLP1; PROTEIN KINASE; PROTEIN P53; TRANSFER RNA; UNCLASSIFIED DRUG;

ENZYME ACTIVITY; GENETIC ANALYSIS; MAMMAL; METABOLISM; NEUROLOGY; RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL LOSS; CONTROLLED STUDY; DENERVATION; DIAPHRAGM; EMBRYO; EXON; FEMALE; GENE ACTIVITY; MALE; MOTOR DYSFUNCTION; MOUSE; MUSCLE ATROPHY; MUSCLE INNERVATION; MUSCLE WEAKNESS; NERVE CELL NECROSIS; NERVE FIBER DEGENERATION; NEUROMUSCULAR JUNCTION DISORDER; NEUROMUSCULAR SYNAPSE; NEWBORN; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; PARALYSIS; PERIPHERAL NERVE; PRIORITY JOURNAL; RESPIRATORY FAILURE; RNA METABOLISM; RNA PROCESSING; SPINAL CORD MOTONEURON; TRANSGENIC MOUSE;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; ANIMALS, NEWBORN; AXONS; CELL DEATH; DIAPHRAGM; EMBRYO LOSS; EMBRYO, MAMMALIAN; EXONS; FEMALE; FIBROBLASTS; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; MOTOR NEURONS; MUSCULAR ATROPHY, SPINAL; NEUROMUSCULAR DISEASES; OXIDATIVE STRESS; RESPIRATION; RNA PROCESSING, POST-TRANSCRIPTIONAL; RNA, TRANSFER, TYR; SPINAL NERVES; TRANSCRIPTION FACTORS; TUMOR SUPPRESSOR PROTEIN P53; TYROSINE;

MAMMALIA; MUS;

EID: 84875623194     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature11923     Document Type: Article

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