Reduced IGF-1 Signaling Delays Age-Associated Proteotoxicity in Mice

Cell

Volumn 139, Issue 6, 2009, Pages 1157-1169

  Cohen, Ehud ^a   Paulsson, Johan F ^b   Blinder, Pablo ^c   Burstyn Cohen, Tal ^d   Du, Deguo ^b   Estepa, Gabriela ^a   Adame, Anthony ^e   Pham, Hang M ^e   Holzenberger, Martin ^f   Kelly, Jeffery W ^b   Masliah, Eliezer ^e   Dillin, Andrew ^a  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f INSERM   (France)

Author keywords

HUMDISEASE; PROTEINS; SIGNALING

Indexed keywords

AMYLOID BETA PROTEIN; INSULIN; SOMATOMEDIN C; SOMATOMEDIN C RECEPTOR; SYNAPTOPHYSIN;

AGING; ALZHEIMER DISEASE; ANIMAL BEHAVIOR; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CAENORHABDITIS ELEGANS; CELL LOSS; CONTROLLED STUDY; DISEASE MODEL; DRUG RESEARCH; FEMALE; GENETIC CONSERVATION; MALE; MAMMAL; MAZE TEST; MOUSE; NERVE CELL; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN SYNTHESIS; SENILE PLAQUE; SIGNAL TRANSDUCTION; SYMPTOM; WORM;

ANIMALIA; CAENORHABDITIS ELEGANS; MAMMALIA; MUS;

EID: 71449108913     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cell.2009.11.014     Document Type: Article

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