메뉴 건너뛰기




Volumn 116, Issue 2, 2011, Pages 240-247

In vivo regulation of amyloid precursor protein neuronal splicing by microRNAs

Author keywords

alternative splicing; Alzheimer's disease; amyloid precursor protein; microRNA; miR 124; polypyrimidine tract binding protein

Indexed keywords

AMYLOID PRECURSOR PROTEIN; MICRORNA; MICRORNA 124; POLYPYRIMIDINE TRACT BINDING PROTEIN; POLYPYRIMIDINE TRACT BINDING PROTEIN 1; POLYPYRIMIDINE TRACT BINDING PROTEIN 2; UNCLASSIFIED DRUG;

EID: 78650692019     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2010.07097.x     Document Type: Article
Times cited : (189)

References (35)
  • 1
    • 4644309196 scopus 로고    scopus 로고
    • The functions of animal microRNAs
    • Ambros V., (2004) The functions of animal microRNAs. Nature 431, 350-355.
    • (2004) Nature , vol.431 , pp. 350-355
    • Ambros, V.1
  • 2
    • 0344878484 scopus 로고
    • Neuroanatomical localization and quantification of amyloid precursor protein mRNA by in situ hybridization in the brains of normal, aneuploid, and lesioned mice
    • Bendotti C., Forloni G. L., Morgan R. A., O'Hara B. F., Oster-Granite M. L., Reeves R. H., Gearhart J. D., and, Coyle J. T., (1988) Neuroanatomical localization and quantification of amyloid precursor protein mRNA by in situ hybridization in the brains of normal, aneuploid, and lesioned mice. Proc. Natl Acad. Sci. USA 85, 3628-3632.
    • (1988) Proc. Natl Acad. Sci. USA , vol.85 , pp. 3628-3632
    • Bendotti, C.1    Forloni, G.L.2    Morgan, R.A.3    O'Hara, B.F.4    Oster-Granite, M.L.5    Reeves, R.H.6    Gearhart, J.D.7    Coyle, J.T.8
  • 3
    • 77950558348 scopus 로고    scopus 로고
    • Neurons generated from APP/APLP1/APLP2 triple knockout embryonic stem cells behave normally in vitro and in vivo: Lack of evidence for a cell autonomous role of the amyloid precursor protein in neuronal differentiation
    • Bergmans B. A., Shariati S. A., Habets R. L., Verstreken P., Schoonjans L., Muller U., Dotti C. G., and, De Strooper B., (2010) Neurons generated from APP/APLP1/APLP2 triple knockout embryonic stem cells behave normally in vitro and in vivo: lack of evidence for a cell autonomous role of the amyloid precursor protein in neuronal differentiation. Stem Cells 28, 399-406.
    • (2010) Stem Cells , vol.28 , pp. 399-406
    • Bergmans, B.A.1    Shariati, S.A.2    Habets, R.L.3    Verstreken, P.4    Schoonjans, L.5    Muller, U.6    Dotti, C.G.7    De Strooper, B.8
  • 4
    • 0034695452 scopus 로고    scopus 로고
    • Identification of cis-elements regulating exon 15 splicing of the amyloid precursor protein pre-mRNA
    • Bergsdorf C., Paliga K., Kreger S., Masters C. L., and, Beyreuther K., (2000) Identification of cis-elements regulating exon 15 splicing of the amyloid precursor protein pre-mRNA. J. Biol. Chem. 275, 2046-2056.
    • (2000) J. Biol. Chem. , vol.275 , pp. 2046-2056
    • Bergsdorf, C.1    Paliga, K.2    Kreger, S.3    Masters, C.L.4    Beyreuther, K.5
  • 5
    • 33846135109 scopus 로고    scopus 로고
    • MicroRNAs regulate the expression of the alternative splicing factor nPTB during muscle development
    • Boutz P. L., Chawla G., Stoilov P., and, Black D. L., (2007) MicroRNAs regulate the expression of the alternative splicing factor nPTB during muscle development. Genes Dev. 21, 71-84.
    • (2007) Genes Dev. , vol.21 , pp. 71-84
    • Boutz, P.L.1    Chawla, G.2    Stoilov, P.3    Black, D.L.4
  • 6
    • 47849124269 scopus 로고    scopus 로고
    • Identification of miRNA changes in Alzheimer's disease brain and CSF yields putative biomarkers and insights into disease pathways
    • Cogswell J. P., Ward J., Taylor I. A., et al. (2008) Identification of miRNA changes in Alzheimer's disease brain and CSF yields putative biomarkers and insights into disease pathways. J. Alzheimers Dis. 14, 27-41.
    • (2008) J. Alzheimers Dis. , vol.14 , pp. 27-41
    • Cogswell, J.P.1    Ward, J.2    Taylor, I.A.3
  • 7
    • 33144481470 scopus 로고    scopus 로고
    • Reciprocal actions of REST and a microRNA promote neuronal identity
    • Conaco C., Otto S., Han J. J., and, Mandel G., (2006) Reciprocal actions of REST and a microRNA promote neuronal identity. Proc. Natl Acad. Sci. USA 103, 2422-2427.
    • (2006) Proc. Natl Acad. Sci. USA , vol.103 , pp. 2422-2427
    • Conaco, C.1    Otto, S.2    Han, J.J.3    Mandel, G.4
  • 8
    • 78049374467 scopus 로고    scopus 로고
    • Novel research horizons for presenilins and gamma-secretases in cell biology and disease
    • De Strooper B., and, Annaert W., (2010) Novel research horizons for presenilins and gamma-secretases in cell biology and disease. Annu. Rev. Cell Dev. Biol. 26, 235-260.
    • (2010) Annu. Rev. Cell Dev. Biol. , vol.26 , pp. 235-260
    • De Strooper, B.1    Annaert, W.2
  • 9
    • 34347240373 scopus 로고    scopus 로고
    • A role for SC35 and hnRNPA1 in the determination of amyloid precursor protein isoforms
    • Donev R., Newall A., Thome J., and, Sheer D., (2007) A role for SC35 and hnRNPA1 in the determination of amyloid precursor protein isoforms. Mol. Psychiatry 12, 681-690.
    • (2007) Mol. Psychiatry , vol.12 , pp. 681-690
    • Donev, R.1    Newall, A.2    Thome, J.3    Sheer, D.4
  • 11
    • 0025373986 scopus 로고
    • Expression of beta amyloid protein precursor mRNAs: Recognition of a novel alternatively spliced form and quantitation in Alzheimer's disease using PCR
    • Golde T. E., Estus S., Usiak M., Younkin L. H., and, Younkin S. G., (1990) Expression of beta amyloid protein precursor mRNAs: recognition of a novel alternatively spliced form and quantitation in Alzheimer's disease using PCR. Neuron 4, 253-267.
    • (1990) Neuron , vol.4 , pp. 253-267
    • Golde, T.E.1    Estus, S.2    Usiak, M.3    Younkin, L.H.4    Younkin, S.G.5
  • 12
    • 63349094897 scopus 로고    scopus 로고
    • Alterations of the microRNA network cause neurodegenerative disease
    • Hebert S. S., and, De Strooper B., (2009) Alterations of the microRNA network cause neurodegenerative disease. Trends Neurosci. 32, 199-206.
    • (2009) Trends Neurosci. , vol.32 , pp. 199-206
    • Hebert, S.S.1    De Strooper, B.2
  • 13
    • 33745584643 scopus 로고    scopus 로고
    • Regulated intramembrane proteolysis of amyloid precursor protein and regulation of expression of putative target genes
    • Hebert S. S., Serneels L., Tolia A., Craessaerts K., Derks C., Filippov M. A., Muller U., and, De Strooper B., (2006) Regulated intramembrane proteolysis of amyloid precursor protein and regulation of expression of putative target genes. EMBO Rep. 7, 739-745.
    • (2006) EMBO Rep. , vol.7 , pp. 739-745
    • Hebert, S.S.1    Serneels, L.2    Tolia, A.3    Craessaerts, K.4    Derks, C.5    Filippov, M.A.6    Muller, U.7    De Strooper, B.8
  • 17
    • 0026040620 scopus 로고
    • Quantitative measurement of alternatively spliced amyloid precursor protein mRNA expression in Alzheimer's disease and normal brain by S1 nuclease protection analysis
    • Jacobsen J. S., Blume A. J., and, Vitek M. P., (1991) Quantitative measurement of alternatively spliced amyloid precursor protein mRNA expression in Alzheimer's disease and normal brain by S1 nuclease protection analysis. Neurobiol. Aging 12, 585-592.
    • (1991) Neurobiol. Aging , vol.12 , pp. 585-592
    • Jacobsen, J.S.1    Blume, A.J.2    Vitek, M.P.3
  • 18
    • 77950513681 scopus 로고    scopus 로고
    • MicroRNAs coordinate an alternative splicing network during mouse postnatal heart development
    • Kalsotra A., Wang K., Li P. F., and, Cooper T. A., (2010) MicroRNAs coordinate an alternative splicing network during mouse postnatal heart development. Genes Dev. 24, 653-658.
    • (2010) Genes Dev. , vol.24 , pp. 653-658
    • Kalsotra, A.1    Wang, K.2    Li, P.F.3    Cooper, T.A.4
  • 20
    • 77956903474 scopus 로고    scopus 로고
    • MicroRNA-16 targets amyloid precursor protein to potentially modulate Alzheimer's-associated pathogenesis in SAMP8 mice
    • [Epub ahead of print].
    • Liu W., Liu C., Zhu J., Shu P., Yin B., Gong Y., Qiang B., Yuan J., and, Peng X., (2010) MicroRNA-16 targets amyloid precursor protein to potentially modulate Alzheimer's-associated pathogenesis in SAMP8 mice. Neurobiol. Aging [Epub ahead of print].
    • (2010) Neurobiol. Aging
    • Liu, W.1    Liu, C.2    Zhu, J.3    Shu, P.4    Yin, B.5    Gong, Y.6    Qiang, B.7    Yuan, J.8    Peng, X.9
  • 21
    • 33847203593 scopus 로고    scopus 로고
    • Micro-RNA speciation in fetal, adult and Alzheimer's disease hippocampus
    • Lukiw W. J., (2007) Micro-RNA speciation in fetal, adult and Alzheimer's disease hippocampus. Neuroreport 18, 297-300.
    • (2007) Neuroreport , vol.18 , pp. 297-300
    • Lukiw, W.J.1
  • 22
    • 41349092509 scopus 로고    scopus 로고
    • Multilevel regulation of gene expression by microRNAs
    • Makeyev E. V., and, Maniatis T., (2008) Multilevel regulation of gene expression by microRNAs. Science 319, 1789-1790.
    • (2008) Science , vol.319 , pp. 1789-1790
    • Makeyev, E.V.1    Maniatis, T.2
  • 23
    • 34547212309 scopus 로고    scopus 로고
    • The MicroRNA miR-124 promotes neuronal differentiation by triggering brain-specific alternative pre-mRNA splicing
    • Makeyev E. V., Zhang J., Carrasco M. A., and, Maniatis T., (2007) The MicroRNA miR-124 promotes neuronal differentiation by triggering brain-specific alternative pre-mRNA splicing. Mol. Cell 27, 435-448.
    • (2007) Mol. Cell , vol.27 , pp. 435-448
    • Makeyev, E.V.1    Zhang, J.2    Carrasco, M.A.3    Maniatis, T.4
  • 25
    • 77954996105 scopus 로고    scopus 로고
    • MiR-107 is reduced in Alzheimer's disease brain neocortex: Validation study
    • Nelson P. T., and, Wang W. X., (2010) MiR-107 is reduced in Alzheimer's disease brain neocortex: validation study. J. Alzheimers Dis. 21, 75-79.
    • (2010) J. Alzheimers Dis. , vol.21 , pp. 75-79
    • Nelson, P.T.1    Wang, W.X.2
  • 26
    • 0025118036 scopus 로고
    • The Alzheimer amyloid precursor-related transcript lacking the beta/A4 sequence is specifically increased in Alzheimer's disease brain
    • Neve R. L., Rogers J., and, Higgins G. A., (1990) The Alzheimer amyloid precursor-related transcript lacking the beta/A4 sequence is specifically increased in Alzheimer's disease brain. Neuron 5, 329-338.
    • (1990) Neuron , vol.5 , pp. 329-338
    • Neve, R.L.1    Rogers, J.2    Higgins, G.A.3
  • 27
    • 77953312769 scopus 로고    scopus 로고
    • Joint genome-wide profiling of miRNA and mRNA expression in Alzheimer's disease cortex reveals altered miRNA regulation
    • Nunez-Iglesias J., Liu C. C., Morgan T. E., Finch C. E., and, Zhou X. J., (2010) Joint genome-wide profiling of miRNA and mRNA expression in Alzheimer's disease cortex reveals altered miRNA regulation. PLoS ONE 5, e8898.
    • (2010) PLoS ONE , vol.5
    • Nunez-Iglesias, J.1    Liu, C.C.2    Morgan, T.E.3    Finch, C.E.4    Zhou, X.J.5
  • 28
    • 65349085532 scopus 로고    scopus 로고
    • MicroRNA-124: Micromanager of neurogenesis
    • Papagiannakopoulos T., and, Kosik K. S., (2009) MicroRNA-124: micromanager of neurogenesis. Cell Stem Cell 4, 375-376.
    • (2009) Cell Stem Cell , vol.4 , pp. 375-376
    • Papagiannakopoulos, T.1    Kosik, K.S.2
  • 30
    • 0033937999 scopus 로고    scopus 로고
    • A trans-acting factor, isolated by the three-hybrid system, that influences alternative splicing of the amyloid precursor protein minigene
    • Poleev A., Hartmann A., and, Stamm S., (2000) A trans-acting factor, isolated by the three-hybrid system, that influences alternative splicing of the amyloid precursor protein minigene. Eur. J. Biochem. 267, 4002-4010.
    • (2000) Eur. J. Biochem. , vol.267 , pp. 4002-4010
    • Poleev, A.1    Hartmann, A.2    Stamm, S.3
  • 31
    • 0028875687 scopus 로고
    • Levels and alternative splicing of amyloid beta protein precursor (APP) transcripts in brains of APP transgenic mice and humans with Alzheimer's disease
    • Rockenstein E. M., McConlogue L., Tan H., Power M., Masliah E., and, Mucke L., (1995) Levels and alternative splicing of amyloid beta protein precursor (APP) transcripts in brains of APP transgenic mice and humans with Alzheimer's disease. J. Biol. Chem. 270, 28257-28267.
    • (1995) J. Biol. Chem. , vol.270 , pp. 28257-28267
    • Rockenstein, E.M.1    McConlogue, L.2    Tan, H.3    Power, M.4    Masliah, E.5    Mucke, L.6
  • 32
    • 77952336221 scopus 로고    scopus 로고
    • Aberrant microRNA expression in the brains of neurodegenerative diseases: MiR-29a decreased in Alzheimer disease brains targets neuron navigator-3
    • Shioya M., Obayashi S., Tabunoki H., Arima K., Saitoh Y., Ishida T., and, Satoh J., (2010) Aberrant microRNA expression in the brains of neurodegenerative diseases: miR-29a decreased in Alzheimer disease brains targets neuron navigator-3. Neuropathol. Appl. Neurobiol. 36, 320-330.
    • (2010) Neuropathol. Appl. Neurobiol. , vol.36 , pp. 320-330
    • Shioya, M.1    Obayashi, S.2    Tabunoki, H.3    Arima, K.4    Saitoh, Y.5    Ishida, T.6    Satoh, J.7
  • 33
    • 0027231763 scopus 로고
    • Cellular specificity and regional distribution of amyloid beta protein precursor alternative transcripts are unaltered in Alzheimer hippocampal formation
    • Tanzi R. E., Wenniger J. J., and, Hyman B. T., (1993) Cellular specificity and regional distribution of amyloid beta protein precursor alternative transcripts are unaltered in Alzheimer hippocampal formation. Brain Res. Mol. Brain Res. 18, 246-252.
    • (1993) Brain Res. Mol. Brain Res. , vol.18 , pp. 246-252
    • Tanzi, R.E.1    Wenniger, J.J.2    Hyman, B.T.3
  • 34
    • 77953319294 scopus 로고    scopus 로고
    • MicroRNA-101 regulates amyloid precursor protein expression in hippocampal neurons
    • Vilardo E., Barbato C., Ciotti M., Cogoni C., and, Ruberti F., (2010) MicroRNA-101 regulates amyloid precursor protein expression in hippocampal neurons. J. Biol. Chem. 285, 18344-18351.
    • (2010) J. Biol. Chem. , vol.285 , pp. 18344-18351
    • Vilardo, E.1    Barbato, C.2    Ciotti, M.3    Cogoni, C.4    Ruberti, F.5
  • 35
    • 38749095507 scopus 로고    scopus 로고
    • The expression of microRNA miR-107 decreases early in Alzheimer's disease and may accelerate disease progression through regulation of beta-site amyloid precursor protein-cleaving enzyme 1
    • Wang W. X., Rajeev B. W., Stromberg A. J., Ren N., Tang G., Huang Q., Rigoutsos I., and, Nelson P. T., (2008) The expression of microRNA miR-107 decreases early in Alzheimer's disease and may accelerate disease progression through regulation of beta-site amyloid precursor protein-cleaving enzyme 1. J. Neurosci. 28, 1213-1223.
    • (2008) J. Neurosci. , vol.28 , pp. 1213-1223
    • Wang, W.X.1    Rajeev, B.W.2    Stromberg, A.J.3    Ren, N.4    Tang, G.5    Huang, Q.6    Rigoutsos, I.7    Nelson, P.T.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.