The age-related accumulation of protein carbonyl in rat liver correlates with the age-related decline in liver proteolytic activities

Journals of Gerontology - Series A Biological Sciences and Medical Sciences

Volumn 54, Issue 8, 1999, Pages

  Vittorini, Simona ^b   Paradiso, Cristina ^b   Donati, Alessio ^b   Cavallini, Gabriella ^b   Masini, Matilde ^b   Gori, Zina ^b   Pollera, Maria ^b   Bergamini, Ettore ^a  

^a UNIVERSITY OF PISA   (Italy)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ALKALINE PROTEINASE; LIVER PROTEIN;

AGING; ANIMAL TISSUE; ARTICLE; BIOACCUMULATION; ENZYME ACTIVITY; LIVER FUNCTION; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; RAT; TISSUE DISTRIBUTION;

ANIMALIA;

EID: 0032860808     PISSN: 10795006     EISSN: None     Source Type: Journal    
DOI: 10.1093/gerona/54.8.B318     Document Type: Article

References (42)

1. Makrides SC. Protein synthesis and degradation during aging and senescence. Biol Rev. 1983;58:343-422.
2. Oliver CN, Ahn B, Moerman EJ, Goldstein S, Stadtman ER. Age-related changes in oxidized proteins. J Biol Chem. 1987;262:5488-5491.
3. Smith CD, Carney JM, Starke-Reed PE, et al. Excess brain protein oxidation and enzyme dysfunction in normal aging and in Alzheimer disease. Proc Natl Acad Sci USA. 1991;88:10540-10543.
4. Carney JM, Starke-Reed PE, Oliver CN, et al. Reversal of age-related increase in brain protein oxidation, decrease in enzyme activity and loss in temporal and spatial memory by chronic administration of the spin-trapping compound N-tert-butyl-alfa-phenylnitrone. Proc Natl Acad Sci USA. 1991;88:3633-3636.
5. Starke-Reed PE, Oliver CN. Protein oxidation and proteolysis during aging and oxidative stress. Arch Biochem Biophys. 1989;275:559-567.
6. Sohal RS, Ku HH, Agarwal S, Forster MJ, Lal H. Oxidative damage, mitochondrial oxidant generation and antioxidant defences during aging and in response to food restriction in the mouse. Mech Ageing Dev. 1994; 74:121-133.
7. Sohal RS, Agarwal S, Dubey A, Orr WC. Protein oxidative damage is associated with life expectancy of houseflies. Proc Natl Acad Sci USA. 1993;90:7255-7259.
8. Conconi M, Swzeda LI, Levine RL, Stadtman ER, Friguet B. Age-related decline of rat liver multicatalytic proteinase activity and protection from oxidative inactivation by heat-shock protein 90. Arch Biochem Biophys. 1994;309:24-28.
9. Rivett AJ. Preferential degradation of the oxidatively modified form of gluthamine synthetase by intracellular mammalian proteases. J Biol Chem. 1985;260:300-305.
10. Pacifici RE, Salo DC, Davies KJ. Macroxyproteinase (M.O.P.): a 670 kDa proteinase complex that degrades oxidatively denatured proteins in red blood cells. Free Radic Biol Med. 1989;7:521-536.
11. Orlowski M. The multicatalytic proteinase complex, a major extralysosomal proteolytic system [Review]. Biochemistry. 1990;29:10289-10297.
12. Rivett AJ. Proteasomes: multicatalytic proteinase complexes [Review]. Biochem J. 1993;291:1-10.
13. Grune T, Reinheckel T, Davies KJA. Degradation of oxidized proteins in mammalian cells. FASEB J. 1997;11:526-534.
14. Agarwal S, Sohal RS. Aging and proteolysis of oxidized protein. Arch Biochem Biophys. 1994;309:24-28.
15. Sahakian JA, Swzeda LI, Friguet B, Kitani K, Levine RL. Aging of the liver: proteolysis of oxidatively modified glutamine synthetase. Arch Biochem Biophys. 1995;318:411-417.
16. Shibatani T, Nazir M, Ward WF. Alteration of rat liver 20S proteasome activities by age and food restriction. J Gerontol Biol Sci. 1996;51A: B316-B322.
17. Cao G, Cutler GC. Protein oxidation and aging. II. Difficulties in measuring alkaline protease activity in tissues using the fluorescamine procedure. Arch Biochem Biophys. 1995;320:195-201.
18. Conconi M, Friguet B. Proteasome inactivation upon aging and on oxidation-effect of HSP 90. Mol Biol Rep. 1997;24:45-50.
19. Blommaart EFC, Luiken JJFP, Meijer AJ. Autophagic proteolysis: control and specificity. Histochem J. 1997;29:365-389.
20. Bergamini E. Protein degradation and modification. Introduction and overview. Ann NY Acad Sci. 1992;663:43-47.
21. Vittorini S, Paradiso C, Gori Z, Pollera M, Bergamini E. The levels of carbonyl in crude protein extracts of several tissues from male Sprague-Dawley rats do not increase with age and are not affected by anti-aging diet restriction. Aging Clin Exp Res. 1995;7:480-481.
22. Reznick AZ, Packer L. Oxidative damage to proteins: spectrophotometric method for carbonyl assay. Methods Enzymol. 1994;233:357-363.
23. Barrett AJ. Fluorimetric assay for cathepsin B and cathepsin H with methylcoumaryl amide substrates. Biochem J. 1980;187:909-912.
24. Rivett AJ, Savory PJ, Djaballah H. Multicatalytic endopeptidase complex: proteasome. Methods Enzymol. 1994;244:331-350.
25. Shibatani T, Ward W.F. Effect of age and food restriction on alkaline protease activity in rat liver. J Gerontol Biol Sci. 1996;51A:175-178.
26. Seglen PO. Preparation of isolated rat liver cells. In: Methods in Cell Biology. New York: Academic Press; 1976:29-83.
27. Seglen PO, Gordon PB. 3-Methyladenine: specific inhibitor of autophagic/lysosomal protein degradation in isolated rat hepatocytes. Proc Natl Acad Sci USA. 1982;79:1889-1892.
28. Venerando R, Miotto G, Kadowaki M, Siliprandi N, Mortimore GE. Multiphasic control of proteolysis by leucine and alanine in the isolated rat hepatocytes. Am J Physiol. 1994;266:455-461.
29. Stadtman ER. The status of oxidatively modified proteins as a marker of aging. In: Esser K, Martin GM, eds. Molecular Aspects of Aging. New York: J. Wiley and Sons; 1995.
30. Herman D. Aging: a theory based on free radical and radiation chemistry. J Gerontol. 1956;11:298-300.
31. Ames BN. Endogenous oxidative DNA damage, aging and cancer. Free Radic Res Commun. 1989;7:121-128.
32. Stadtman ER. Protein oxidation and aging. Science. 1992;257: 1220-1224.
33. Cao G, Cutler RG. Protein oxidation and aging. I. Difficulties in measuring reactive protein carbonyls in tissues using 2,4-dinitrophenylhidrazine. Arch Biochem Biophys. 1995;320:106-114.
34. Chung MH, Kasai H, Nishimura S, Yu BP. Protection of DNA damage by dietary restriction. Free Radic Biol Med. 1992;12:523-525.
35. Tian L, Cai Q, Bowen R, Wei H. Effect of caloric restriction on age-related oxidative modifications of macromolecules and lymphocyte proliferation in rats. Free Radic Biol Med. 1995;19:858-865.
36. Sohal RS, Agarwal S, Candas M, Foster MJ, Lal H. Effect of age and caloric restriction on DNA oxidative damage in different tissues of C57BL/6 mice. Mech Ageing Dev. 1994;76:215-224.
37. Sohal RS, Allen RJ. Oxidative stress as a causal factor in differentiation and aging: a unifying hypothesis. Exp Gerontol. 1990;25:499-522.
38. Sohal RS, Orr WC. Oxidative stress: a causal factor in aging. In: Esser K, Martin GM, eds. Molecular Aspects of Aging. New York: J. Wiley and Sons; 1995.
39. Sohal RS, Ku HH, Agarwal S. Biochemical correlates of longevity in two closely related rodent species. Biochem Biophys Res Commun. 1993; 196:7-11.
40. Mortimore GE, Pösö AR, Lardeux BR. Mechanism and regulation of protein degradation in the liver. Diabetes/Metabolism Rev. 1989;5:49-70.
41. Dunn WA. Autophagy and related mechanisms of lysosome mediated protein degradation. Trends Cell Biol. 1994;4:139-143.
42. Seglen PO, Bohley P. Autophagy and other vacuolar protein degradation mechanisms. Experientia. 1992;48:158-172.