Genome-wide RNA interference screen identifies previously undescribed regulators of polyglutamine aggregation

Proceedings of the National Academy of Sciences of the United States of America

Volumn 101, Issue 17, 2004, Pages 6403-6408

  Nollen, Ellen A A ^a   Garcia, Susana M ^b   Van Haaften, Gijs ^a   Kim, Soojin ^b   Chavez, Alejandro ^b   Morimoto, Richard I ^b   Plasterk, Ronald H A ^a  

^a HUBRECHT INSTITUTE   (Netherlands)

^b NORTHWESTERN UNIVERSITY   (United States)

Author keywords

Neurodegenerative diseases; Protein misfolding

Indexed keywords

HYBRID PROTEIN; POLYGLUTAMINE; PROTEIN; YELLOW FLUORESCENT PROTEIN;

AGE; ARTICLE; CAENORHABDITIS ELEGANS; DEGENERATIVE DISEASE; GENE IDENTIFICATION; GENE REPRESSION; GENETIC DISORDER; HOMEOSTASIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN MISFOLDING; PROTEIN STRUCTURE; PROTEIN SYNTHESIS; PROTEIN TRANSPORT; RNA INTERFERENCE; RNA METABOLISM; TRANSGENIC ANIMAL;

ANIMALS; BLOTTING, WESTERN; CAENORHABDITIS ELEGANS; GENOME; MICROSCOPY, ELECTRON; PEPTIDES; RNA INTERFERENCE;

ANIMALIA; CAENORHABDITIS; CAENORHABDITIS ELEGANS;

EID: 2342652188     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0307697101     Document Type: Article

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