Signal integration by mTORC1 coordinates nutrient input with biosynthetic output

Nature Cell Biology

Volumn 15, Issue 6, 2013, Pages 555-564

  Dibble, Christian C ^a,b   Manning, Brendan D ^c  

^a BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; ADENYLATE KINASE; AMINO ACID; CARBAMOYL PHOSPHATE SYNTHASE; EPIDERMAL GROWTH FACTOR; G PROTEIN COUPLED RECEPTOR; GLUCOSE; GLUCOSE 6 PHOSPHATE DEHYDROGENASE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; INITIATION FACTOR 4E; INOSITOL POLYPHOSPHATE; MAMMALIAN TARGET OF RAPAMYCIN; MECHANISTIC TARGET OF RAPAMYCIN COMPLEX 1; OXYGEN; PHOSPHATIDYLINOSITOL 3 PHOSPHATE; PHOSPHOLIPASE D; PLATELET DERIVED GROWTH FACTOR; PROTEIN KINASE B; PROTEIN P14; PROTEIN P18; PROTEIN P62; PROTEIN TYROSINE KINASE; RHEB PROTEIN; SOMATOMEDIN; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; STEROL REGULATORY ELEMENT BINDING PROTEIN 2; SYNAPTOPHYSIN; UNCLASSIFIED DRUG; VASCULOTROPIN; VON HIPPEL LINDAU PROTEIN;

AUTOPHAGY; BIOSYNTHESIS; CELL ENERGY; CELL FUNCTION; CELL GROWTH; CELL METABOLISM; ENZYME REGULATION; HUMAN; METABOLIC REGULATION; MOLECULAR MECHANICS; NONHUMAN; NUTRIENT CONTENT; NUTRIENT DYNAMICS; NUTRITIONAL STATUS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; PROTEIN SECRETION; PROTEIN TARGETING; REVIEW; SIGNAL TRANSDUCTION;

AMINO ACIDS; ANIMALS; BIOSYNTHETIC PATHWAYS; ENERGY METABOLISM; FOOD; GLUCOSE; HUMANS; METABOLIC NETWORKS AND PATHWAYS; MULTIPROTEIN COMPLEXES; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES;

EUKARYOTA;

EID: 84878532557     PISSN: 14657392     EISSN: 14764679     Source Type: Journal    
DOI: 10.1038/ncb2763     Document Type: Review

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