PRAS40 Is an Insulin-Regulated Inhibitor of the mTORC1 Protein Kinase

Molecular Cell

Volumn 25, Issue 6, 2007, Pages 903-915

  Sancak, Yasemin ^a,c   Thoreen, Carson C ^a,c   Peterson, Timothy R ^a,c   Lindquist, Robert A ^a,c   Kang, Seong A ^a,c   Spooner, Eric ^a   Carr, Steven A ^b   Sabatini, David M ^a,b,c  

^a WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

^b BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^c MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

SIGNALING

Indexed keywords

INSULIN; MAMMALIAN TARGET OF RAPAMYCIN; MAMMALIAN TARGET OF RAPAMYCIN INHIBITOR; PROTEIN KINASE B; PROTEIN PRAS40; RHEB PROTEIN; S6 KINASE; SODIUM CHLORIDE; UNCLASSIFIED DRUG;

ARTICLE; CELL GROWTH; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME REGULATION; ENZYME SUBSTRATE; HUMAN; INSULIN RESPONSE; NONHUMAN; PROTEIN BINDING; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

ANIMALS; CARRIER PROTEINS; CELL LINE; ENZYME INHIBITORS; HUMANS; INSULIN; KINETICS; MICE; PHOSPHOPROTEINS; PHOSPHORYLATION; PROTEIN KINASE INHIBITORS; TRANSCRIPTION FACTORS;

RAPTORES;

EID: 33947264077     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molcel.2007.03.003     Document Type: Article

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