SREBP Activity Is Regulated by mTORC1 and Contributes to Akt-Dependent Cell Growth

Cell Metabolism

Volumn 8, Issue 3, 2008, Pages 224-236

  Porstmann, Thomas ^a   Santos, Claudio R ^a   Griffiths, Beatrice ^a   Cully, Megan ^b   Wu, Mary ^c   Leevers, Sally ^d   Griffiths, John R ^e   Chung, Yuen Li ^f   Schulze, Almut ^a  

^a Gene Expression Analysis Laboratory   (United Kingdom)

^b Signal Transduction Laboratory   (United Kingdom)

^c Developmental Signalling Laboratory   (United Kingdom)

^d IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^e CANCER RESEARCH UK CAMBRIDGE RESEARCH INSTITUTE   (United Kingdom)

^f ROYAL MARSDEN HOSPITAL   (United Kingdom)

Author keywords

HUMDISEASE; SIGNALING

Indexed keywords

LIPID; MAMMALIAN TARGET OF RAPAMYCIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; RAPAMYCIN; STEROL REGULATORY ELEMENT BINDING PROTEIN; STEROL REGULATORY ELEMENT BINDING PROTEIN 1;

ANIMAL CELL; ARTICLE; CELL GROWTH; CELL NUCLEUS; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME REGULATION; FLY; GENE SILENCING; GROWTH INHIBITION; HUMAN; HUMAN CELL; LIPOGENESIS; NONHUMAN; ORGAN SIZE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS REGULATION; SIGNAL TRANSDUCTION;

ANIMALS; CELL ENLARGEMENT; CELL NUCLEUS; CELLS, CULTURED; DROSOPHILA; DROSOPHILA PROTEINS; GENE EXPRESSION; LIPIDS; PROTO-ONCOGENE PROTEINS C-AKT; RNA INTERFERENCE; SIGNAL TRANSDUCTION; SIROLIMUS; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; TRANSCRIPTION FACTORS;

EID: 50049116472     PISSN: 15504131     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cmet.2008.07.007     Document Type: Article

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