A unifying model for mTORC1-mediated regulation of mRNA translation

Nature

Volumn 485, Issue 7396, 2012, Pages 109-113

  Thoreen, Carson C ^a,b,c   Chantranupong, Lynne ^c,d,e   Keys, Heather R ^c,d,e   Wang, Tim ^c,d   Gray, Nathanael S ^a,b   Sabatini, David M ^c,d,e  

^a DANA FARBER CANCER INSTITUTE   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

^d MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^e BROAD INSTITUTE OF MIT AND HARVARD   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INITIATION FACTOR 4E; INITIATION FACTOR 4E BINDING PROTEIN; INITIATION FACTOR 4G; INITIATION FACTOR 4G1; MAMMALIAN TARGET OF RAPAMYCIN; MAMMALIAN TARGET OF RAPAMYCIN C1; MAMMALIAN TARGET OF RAPAMYCIN INHIBITOR; MESSENGER RNA; TORIN 1; UNCLASSIFIED DRUG; Y BOX BINDING PROTEIN 1;

CHEMICAL BINDING; INHIBITOR; MITOCHONDRIAL DNA; PROTEIN;

5' UNTRANSLATED REGION; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; INHIBITION KINETICS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; RIBOSOME; TERMINAL OLIGOPYRIMIDINE TRACT; TRANSLATION INITIATION; TRANSLATION REGULATION;

5' UNTRANSLATED REGIONS; ANIMALS; BASE SEQUENCE; CELL LINE, TUMOR; EUKARYOTIC INITIATION FACTOR-4E; EUKARYOTIC INITIATION FACTOR-4G; GENE EXPRESSION REGULATION; HUMANS; MALE; MICE; MODELS, BIOLOGICAL; NAPHTHYRIDINES; NUCLEOTIDE MOTIFS; PHOSPHORYLATION; PROSTATIC NEOPLASMS; PROTEIN BINDING; PROTEIN BIOSYNTHESIS; PROTEINS; RIBOSOMES; RNA, MESSENGER;

EID: 84860527756     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature11083     Document Type: Article

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