-
1
-
-
33750155593
-
Insulin and amino-acid regulation of mTOR signaling and kinase activity through the Rheb GTPase
-
Avruch J., Hara K., Lin Y., Liu M., Long X., Ortiz-Vega S., Yonezawa K. Insulin and amino-acid regulation of mTOR signaling and kinase activity through the Rheb GTPase. Oncogene 2006, 25:6361-6372.
-
(2006)
Oncogene
, vol.25
, pp. 6361-6372
-
-
Avruch, J.1
Hara, K.2
Lin, Y.3
Liu, M.4
Long, X.5
Ortiz-Vega, S.6
Yonezawa, K.7
-
2
-
-
34548847172
-
Diabetic larvae and obese flies-emerging studies of metabolism in Drosophila
-
Baker K.D., Thummel C.S. Diabetic larvae and obese flies-emerging studies of metabolism in Drosophila. Cell Metab. 2007, 6:257-266.
-
(2007)
Cell Metab.
, vol.6
, pp. 257-266
-
-
Baker, K.D.1
Thummel, C.S.2
-
3
-
-
2342559981
-
The TOR pathway: a target for cancer therapy
-
Bjornsti M.A., Houghton P.J. The TOR pathway: a target for cancer therapy. Nat. Rev. Cancer 2004, 4:335-348.
-
(2004)
Nat. Rev. Cancer
, vol.4
, pp. 335-348
-
-
Bjornsti, M.A.1
Houghton, P.J.2
-
4
-
-
25444457577
-
HVps34 is a nutrient-regulated lipid kinase required for activation of p70 S6 kinase
-
Byfield M.P., Murray J.T., Backer J.M. hVps34 is a nutrient-regulated lipid kinase required for activation of p70 S6 kinase. J. Biol. Chem. 2005, 280:33076-33082.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 33076-33082
-
-
Byfield, M.P.1
Murray, J.T.2
Backer, J.M.3
-
5
-
-
34147141941
-
A MAP4 kinase related to Ste20 is a nutrient-sensitive regulator of mTOR signalling
-
Findlay G.M., Yan L., Procter J., Mieulet V., Lamb R.F. A MAP4 kinase related to Ste20 is a nutrient-sensitive regulator of mTOR signalling. Biochem. J. 2007, 403:13-20.
-
(2007)
Biochem. J.
, vol.403
, pp. 13-20
-
-
Findlay, G.M.1
Yan, L.2
Procter, J.3
Mieulet, V.4
Lamb, R.F.5
-
6
-
-
34347220473
-
Defining the role of mTOR in cancer
-
Guertin D.A., Sabatini D.M. Defining the role of mTOR in cancer. Cancer Cell 2007, 12:9-22.
-
(2007)
Cancer Cell
, vol.12
, pp. 9-22
-
-
Guertin, D.A.1
Sabatini, D.M.2
-
7
-
-
42649112409
-
Amino acids activate mTOR complex 1 via Ca2+/CaM signaling to hVps34
-
Gulati P., Gaspers L.D., Dann S.G., Joaquin M., Nobukuni T., Natt F., Kozma S.C., Thomas A.P., Thomas G. Amino acids activate mTOR complex 1 via Ca2+/CaM signaling to hVps34. Cell Metab. 2008, 7:456-465.
-
(2008)
Cell Metab.
, vol.7
, pp. 456-465
-
-
Gulati, P.1
Gaspers, L.D.2
Dann, S.G.3
Joaquin, M.4
Nobukuni, T.5
Natt, F.6
Kozma, S.C.7
Thomas, A.P.8
Thomas, G.9
-
8
-
-
4043171462
-
Upstream and downstream of mTOR
-
Hay N., Sonenberg N. Upstream and downstream of mTOR. Genes Dev. 2004, 18:1926-1945.
-
(2004)
Genes Dev.
, vol.18
, pp. 1926-1945
-
-
Hay, N.1
Sonenberg, N.2
-
9
-
-
44149127993
-
The class III PI(3)K Vps34 promotes autophagy and endocytosis but not TOR signaling in Drosophila
-
Juhasz G., Hill J.H., Yan Y., Sass M., Baehrecke E.H., Backer J.M., Neufeld T.P. The class III PI(3)K Vps34 promotes autophagy and endocytosis but not TOR signaling in Drosophila. J. Cell Biol. 2008, 181:655-666.
-
(2008)
J. Cell Biol.
, vol.181
, pp. 655-666
-
-
Juhasz, G.1
Hill, J.H.2
Yan, Y.3
Sass, M.4
Baehrecke, E.H.5
Backer, J.M.6
Neufeld, T.P.7
-
10
-
-
48649085816
-
Regulation of TORC1 by Rag GTPases in nutrient response
-
Kim E., Goraksha-Hicks P., Li L., Neufeld T.P., Guan K.L. Regulation of TORC1 by Rag GTPases in nutrient response. Nat. Cell Biol. 2008, 10:935-945.
-
(2008)
Nat. Cell Biol.
, vol.10
, pp. 935-945
-
-
Kim, E.1
Goraksha-Hicks, P.2
Li, L.3
Neufeld, T.P.4
Guan, K.L.5
-
11
-
-
20444456317
-
Amino acid-dependent modulation of glucose metabolism in humans
-
Krebs M. Amino acid-dependent modulation of glucose metabolism in humans. Eur. J. Clin. Invest. 2005, 35:351-354.
-
(2005)
Eur. J. Clin. Invest.
, vol.35
, pp. 351-354
-
-
Krebs, M.1
-
12
-
-
0029559573
-
A novel partner for the GTP-bound forms of rho and rac
-
Madaule P., Furuyashiki T., Reid T., Ishizaki T., Watanabe G., Morii N., Narumiya S. A novel partner for the GTP-bound forms of rho and rac. FEBS Lett. 1995, 377:243-248.
-
(1995)
FEBS Lett.
, vol.377
, pp. 243-248
-
-
Madaule, P.1
Furuyashiki, T.2
Reid, T.3
Ishizaki, T.4
Watanabe, G.5
Morii, N.6
Narumiya, S.7
-
13
-
-
26444575415
-
Amino acids mediate mTOR/raptor signaling through activation of class 3 phosphatidylinositol 3OH-kinase
-
Nobukuni T., Joaquin M., Roccio M., Dann S.G., Kim S.Y., Gulati P., Byfield M.P., Backer J.M., Natt F., Bos J.L., Zwartkruis F.J., Thomas G. Amino acids mediate mTOR/raptor signaling through activation of class 3 phosphatidylinositol 3OH-kinase. Proc. Natl. Acad. Sci. U. S. A. 2005, 102:14238-14243.
-
(2005)
Proc. Natl. Acad. Sci. U. S. A.
, vol.102
, pp. 14238-14243
-
-
Nobukuni, T.1
Joaquin, M.2
Roccio, M.3
Dann, S.G.4
Kim, S.Y.5
Gulati, P.6
Byfield, M.P.7
Backer, J.M.8
Natt, F.9
Bos, J.L.10
Zwartkruis, F.J.11
Thomas, G.12
-
14
-
-
45849105156
-
The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1
-
Sancak Y., Peterson T.R., Shaul Y.D., Lindquist R.A., Thoreen C.C., Bar-Peled L., Sabatini D.M. The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1. Science 2008, 320:1496-1501.
-
(2008)
Science
, vol.320
, pp. 1496-1501
-
-
Sancak, Y.1
Peterson, T.R.2
Shaul, Y.D.3
Lindquist, R.A.4
Thoreen, C.C.5
Bar-Peled, L.6
Sabatini, D.M.7
-
15
-
-
23944525416
-
4E-BP functions as a metabolic brake used under stress conditions but not during normal growth
-
Teleman A.A., Chen Y.W., Cohen S.M. 4E-BP functions as a metabolic brake used under stress conditions but not during normal growth. Genes Dev. 2005, 19:1844-1848.
-
(2005)
Genes Dev.
, vol.19
, pp. 1844-1848
-
-
Teleman, A.A.1
Chen, Y.W.2
Cohen, S.M.3
-
16
-
-
22944488274
-
Drosophila melted modulates FOXO and TOR activity
-
Teleman A.A., Chen Y.W., Cohen S.M. Drosophila melted modulates FOXO and TOR activity. Dev. Cell 2005, 9:271-281.
-
(2005)
Dev. Cell
, vol.9
, pp. 271-281
-
-
Teleman, A.A.1
Chen, Y.W.2
Cohen, S.M.3
-
17
-
-
37449029143
-
Nutritional control of protein biosynthetic capacity by insulin via Myc in Drosophila
-
Teleman A.A., Hietakangas V., Sayadian A.C., Cohen S.M. Nutritional control of protein biosynthetic capacity by insulin via Myc in Drosophila. Cell Metab. 2008, 7:21-32.
-
(2008)
Cell Metab.
, vol.7
, pp. 21-32
-
-
Teleman, A.A.1
Hietakangas, V.2
Sayadian, A.C.3
Cohen, S.M.4
-
18
-
-
1542398216
-
Insect adipokinetic hormones: release and integration of flight energy metabolism
-
Van der Horst D.J. Insect adipokinetic hormones: release and integration of flight energy metabolism. Comp. Biochem. Physiol. B Biochem. Mol. Biol. 2003, 136:217-226.
-
(2003)
Comp. Biochem. Physiol. B Biochem. Mol. Biol.
, vol.136
, pp. 217-226
-
-
Van der Horst, D.J.1
-
19
-
-
77649269312
-
PP2A T61 epsilon is an inhibitor of MAP4K3 in nutrient signaling to mTOR
-
Yan L., Mieulet V., Burgess D., Findlay G.M., Sully K., Procter J., Goris J., Janssens V., Morrice N.A., Lamb R.F. PP2A T61 epsilon is an inhibitor of MAP4K3 in nutrient signaling to mTOR. Mol. Cell 2010, 37:633-642.
-
(2010)
Mol. Cell
, vol.37
, pp. 633-642
-
-
Yan, L.1
Mieulet, V.2
Burgess, D.3
Findlay, G.M.4
Sully, K.5
Procter, J.6
Goris, J.7
Janssens, V.8
Morrice, N.A.9
Lamb, R.F.10
-
20
-
-
14844293207
-
PAK and other Rho-associated kinases-effectors with surprisingly diverse mechanisms of regulation
-
Zhao Z.S., Manser E. PAK and other Rho-associated kinases-effectors with surprisingly diverse mechanisms of regulation. Biochem. J. 2005, 386:201-214.
-
(2005)
Biochem. J.
, vol.386
, pp. 201-214
-
-
Zhao, Z.S.1
Manser, E.2
|