-
1
-
-
52449095361
-
The RSK family of kinases: emerging roles in cellular signalling
-
Anjum R., and Blenis J. The RSK family of kinases: emerging roles in cellular signalling. Nat. Rev. Mol. Cell Biol. 9 (2008) 747-758
-
(2008)
Nat. Rev. Mol. Cell Biol.
, vol.9
, pp. 747-758
-
-
Anjum, R.1
Blenis, J.2
-
2
-
-
33750805015
-
Thinking globally and acting locally with TOR
-
Arsham A.M., and Neufeld T.P. Thinking globally and acting locally with TOR. Curr. Opin. Cell Biol. 18 (2006) 589-597
-
(2006)
Curr. Opin. Cell Biol.
, vol.18
, pp. 589-597
-
-
Arsham, A.M.1
Neufeld, T.P.2
-
3
-
-
0028899789
-
Phosphorylation of ribosomal protein S6 is inhibitory for autophagy in isolated rat hepatocytes
-
Blommaart E.F., Luiken J.J., Blommaart P.J., van Woerkom G.M., and Meijer A.J. Phosphorylation of ribosomal protein S6 is inhibitory for autophagy in isolated rat hepatocytes. J. Biol. Chem. 270 (1995) 2320-2326
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 2320-2326
-
-
Blommaart, E.F.1
Luiken, J.J.2
Blommaart, P.J.3
van Woerkom, G.M.4
Meijer, A.J.5
-
4
-
-
13044258426
-
Selective expression of the large neutral amino acid transporter at the blood-brain barrier
-
Boado R.J., Li J.Y., Nagaya M., Zhang C., and Pardridge W.M. Selective expression of the large neutral amino acid transporter at the blood-brain barrier. Proc. Natl. Acad. Sci. USA 96 (1999) 12079-12084
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 12079-12084
-
-
Boado, R.J.1
Li, J.Y.2
Nagaya, M.3
Zhang, C.4
Pardridge, W.M.5
-
5
-
-
0035736260
-
Akt/mTOR pathway is a crucial regulator of skeletal muscle hypertrophy and can prevent muscle atrophy in vivo
-
Bodine S.C., Stitt T.N., Gonzalez M., Kline W.O., Stover G.L., Bauerlein R., Zlotchenko E., Scrimgeour A., Lawrence J.C., Glass D.J., et al. Akt/mTOR pathway is a crucial regulator of skeletal muscle hypertrophy and can prevent muscle atrophy in vivo. Nat. Cell Biol. 3 (2001) 1014-1019
-
(2001)
Nat. Cell Biol.
, vol.3
, pp. 1014-1019
-
-
Bodine, S.C.1
Stitt, T.N.2
Gonzalez, M.3
Kline, W.O.4
Stover, G.L.5
Bauerlein, R.6
Zlotchenko, E.7
Scrimgeour, A.8
Lawrence, J.C.9
Glass, D.J.10
-
6
-
-
0033573016
-
The TOR signaling cascade regulates gene expression in response to nutrients
-
Cardenas M.E., Cutler N.S., Lorenz M.C., Di Como C.J., and Heitman J. The TOR signaling cascade regulates gene expression in response to nutrients. Genes Dev. 13 (1999) 3271-3279
-
(1999)
Genes Dev.
, vol.13
, pp. 3271-3279
-
-
Cardenas, M.E.1
Cutler, N.S.2
Lorenz, M.C.3
Di Como, C.J.4
Heitman, J.5
-
7
-
-
0028271613
-
Overexpression of glutamine synthetase in human primary liver cancer
-
Christa L., Simon M.T., Flinois J.P., Gebhardt R., Brechot C., and Lasserre C. Overexpression of glutamine synthetase in human primary liver cancer. Gastroenterology 106 (1994) 1312-1320
-
(1994)
Gastroenterology
, vol.106
, pp. 1312-1320
-
-
Christa, L.1
Simon, M.T.2
Flinois, J.P.3
Gebhardt, R.4
Brechot, C.5
Lasserre, C.6
-
8
-
-
0141733277
-
A nutrient sensor mechanism controls Drosophila growth
-
Colombani J., Raisin S., Pantalacci S., Radimerski T., Montagne J., and Leopold P. A nutrient sensor mechanism controls Drosophila growth. Cell 114 (2003) 739-749
-
(2003)
Cell
, vol.114
, pp. 739-749
-
-
Colombani, J.1
Raisin, S.2
Pantalacci, S.3
Radimerski, T.4
Montagne, J.5
Leopold, P.6
-
9
-
-
0036899644
-
Elucidating TOR signaling and rapamycin action: lessons from Saccharomyces cerevisiae
-
Crespo J.L., and Hall M.N. Elucidating TOR signaling and rapamycin action: lessons from Saccharomyces cerevisiae. Microbiol. Mol. Biol. Rev. 66 (2002) 579-591
-
(2002)
Microbiol. Mol. Biol. Rev.
, vol.66
, pp. 579-591
-
-
Crespo, J.L.1
Hall, M.N.2
-
11
-
-
33646548305
-
The amino acid sensitive TOR pathway from yeast to mammals
-
Dann S.G., and Thomas G. The amino acid sensitive TOR pathway from yeast to mammals. FEBS Lett. 580 (2006) 2821-2829
-
(2006)
FEBS Lett.
, vol.580
, pp. 2821-2829
-
-
Dann, S.G.1
Thomas, G.2
-
12
-
-
37449034854
-
Beyond aerobic glycolysis: transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis
-
DeBerardinis R.J., Mancuso A., Daikhin E., Nissim I., Yudkoff M., Wehrli S., and Thompson C.B. Beyond aerobic glycolysis: transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis. Proc. Natl. Acad. Sci. USA 104 (2007) 19345-19350
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 19345-19350
-
-
DeBerardinis, R.J.1
Mancuso, A.2
Daikhin, E.3
Nissim, I.4
Yudkoff, M.5
Wehrli, S.6
Thompson, C.B.7
-
13
-
-
0025755232
-
Absorption and metabolic effects of enterally administered glutamine in humans
-
Dechelotte P., Darmaun D., Rongier M., Hecketsweiler B., Rigal O., and Desjeux J.F. Absorption and metabolic effects of enterally administered glutamine in humans. Am. J. Physiol. 260 (1991) G677-G682
-
(1991)
Am. J. Physiol.
, vol.260
-
-
Dechelotte, P.1
Darmaun, D.2
Rongier, M.3
Hecketsweiler, B.4
Rigal, O.5
Desjeux, J.F.6
-
14
-
-
0000045991
-
The growth response of mammalian cells in tissue culture to L-glutamine and L-glutamic acid
-
Eagle H., Oyama V.I., Levy M., Horton C.L., and Fleischman R. The growth response of mammalian cells in tissue culture to L-glutamine and L-glutamic acid. J. Biol. Chem. 218 (1956) 607-616
-
(1956)
J. Biol. Chem.
, vol.218
, pp. 607-616
-
-
Eagle, H.1
Oyama, V.I.2
Levy, M.3
Horton, C.L.4
Fleischman, R.5
-
15
-
-
0036320205
-
Akt maintains cell size and survival by increasing mTOR-dependent nutrient uptake
-
Edinger A.L., and Thompson C.B. Akt maintains cell size and survival by increasing mTOR-dependent nutrient uptake. Mol. Biol. Cell 13 (2002) 2276-2288
-
(2002)
Mol. Biol. Cell
, vol.13
, pp. 2276-2288
-
-
Edinger, A.L.1
Thompson, C.B.2
-
16
-
-
12844262292
-
Ngamma-aryl glutamine analogues as probes of the ASCT2 neutral amino acid transporter binding site
-
Esslinger C.S., Cybulski K.A., and Rhoderick J.F. Ngamma-aryl glutamine analogues as probes of the ASCT2 neutral amino acid transporter binding site. Bioorg. Med. Chem. 13 (2005) 1111-1118
-
(2005)
Bioorg. Med. Chem.
, vol.13
, pp. 1111-1118
-
-
Esslinger, C.S.1
Cybulski, K.A.2
Rhoderick, J.F.3
-
17
-
-
0037097863
-
Mammalian cell size is controlled by mTOR and its downstream targets S6K1 and 4EBP1/eIF4E
-
Fingar D.C., Salama S., Tsou C., Harlow E., and Blenis J. Mammalian cell size is controlled by mTOR and its downstream targets S6K1 and 4EBP1/eIF4E. Genes Dev. 16 (2002) 1472-1487
-
(2002)
Genes Dev.
, vol.16
, pp. 1472-1487
-
-
Fingar, D.C.1
Salama, S.2
Tsou, C.3
Harlow, E.4
Blenis, J.5
-
18
-
-
23044474905
-
Amino acid transporters ASCT2 and LAT1 in cancer: partners in crime?
-
Fuchs B.C., and Bode B.P. Amino acid transporters ASCT2 and LAT1 in cancer: partners in crime?. Semin. Cancer Biol. 15 (2005) 254-266
-
(2005)
Semin. Cancer Biol.
, vol.15
, pp. 254-266
-
-
Fuchs, B.C.1
Bode, B.P.2
-
19
-
-
32444440620
-
Stressing out over survival: glutamine as an apoptotic modulator
-
Fuchs B.C., and Bode B.P. Stressing out over survival: glutamine as an apoptotic modulator. J. Surg. Res. 131 (2006) 26-40
-
(2006)
J. Surg. Res.
, vol.131
, pp. 26-40
-
-
Fuchs, B.C.1
Bode, B.P.2
-
20
-
-
0026693631
-
A novel transiently expressed, integral membrane protein linked to cell activation. Molecular cloning via the rapid degradation signal AUUUA
-
Gaugitsch H.W., Prieschl E.E., Kalthoff F., Huber N.E., and Baumruker T. A novel transiently expressed, integral membrane protein linked to cell activation. Molecular cloning via the rapid degradation signal AUUUA. J. Biol. Chem. 267 (1992) 11267-11273
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 11267-11273
-
-
Gaugitsch, H.W.1
Prieschl, E.E.2
Kalthoff, F.3
Huber, N.E.4
Baumruker, T.5
-
21
-
-
0029128586
-
Glutamine synthetase and hepatocarcinogenesis
-
Gebhardt R., and Williams G.M. Glutamine synthetase and hepatocarcinogenesis. Carcinogenesis 16 (1995) 1673-1681
-
(1995)
Carcinogenesis
, vol.16
, pp. 1673-1681
-
-
Gebhardt, R.1
Williams, G.M.2
-
23
-
-
0032486268
-
Amino acid sufficiency and mTOR regulate p70 S6 kinase and eIF-4E BP1 through a common effector mechanism
-
Hara K., Yonezawa K., Weng Q.P., Kozlowski M.T., Belham C., and Avruch J. Amino acid sufficiency and mTOR regulate p70 S6 kinase and eIF-4E BP1 through a common effector mechanism. J. Biol. Chem. 273 (1998) 14484-14494
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 14484-14494
-
-
Hara, K.1
Yonezawa, K.2
Weng, Q.P.3
Kozlowski, M.T.4
Belham, C.5
Avruch, J.6
-
24
-
-
0033592983
-
Rapamycin-modulated transcription defines the subset of nutrient-sensitive signaling pathways directly controlled by the Tor proteins
-
Hardwick J.S., Kuruvilla F.G., Tong J.K., Shamji A.F., and Schreiber S.L. Rapamycin-modulated transcription defines the subset of nutrient-sensitive signaling pathways directly controlled by the Tor proteins. Proc. Natl. Acad. Sci. USA 96 (1999) 14866-14870
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 14866-14870
-
-
Hardwick, J.S.1
Kuruvilla, F.G.2
Tong, J.K.3
Shamji, A.F.4
Schreiber, S.L.5
-
25
-
-
0036180098
-
Relation between glutamine, branched-chain amino acids, and protein metabolism
-
Holecek M. Relation between glutamine, branched-chain amino acids, and protein metabolism. Nutrition 18 (2002) 130-133
-
(2002)
Nutrition
, vol.18
, pp. 130-133
-
-
Holecek, M.1
-
26
-
-
27744569843
-
mTOR and S6K1 mediate assembly of the translation preinitiation complex through dynamic protein interchange and ordered phosphorylation events
-
Holz M.K., Ballif B.A., Gygi S.P., and Blenis J. mTOR and S6K1 mediate assembly of the translation preinitiation complex through dynamic protein interchange and ordered phosphorylation events. Cell 123 (2005) 569-580
-
(2005)
Cell
, vol.123
, pp. 569-580
-
-
Holz, M.K.1
Ballif, B.A.2
Gygi, S.P.3
Blenis, J.4
-
27
-
-
44449161481
-
The TSC1-TSC2 complex: a molecular switchboard controlling cell growth
-
Huang J., and Manning B.D. The TSC1-TSC2 complex: a molecular switchboard controlling cell growth. Biochem. J. 412 (2008) 179-190
-
(2008)
Biochem. J.
, vol.412
, pp. 179-190
-
-
Huang, J.1
Manning, B.D.2
-
28
-
-
7944235758
-
Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive
-
Jacinto E., Loewith R., Schmidt A., Lin S., Ruegg M.A., Hall A., and Hall M.N. Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive. Nat. Cell Biol. 6 (2004) 1122-1128
-
(2004)
Nat. Cell Biol.
, vol.6
, pp. 1122-1128
-
-
Jacinto, E.1
Loewith, R.2
Schmidt, A.3
Lin, S.4
Ruegg, M.A.5
Hall, A.6
Hall, M.N.7
-
29
-
-
39749100492
-
TOR regulation of AGC kinases in yeast and mammals
-
Jacinto E., and Lorberg A. TOR regulation of AGC kinases in yeast and mammals. Biochem. J. 410 (2008) 19-37
-
(2008)
Biochem. J.
, vol.410
, pp. 19-37
-
-
Jacinto, E.1
Lorberg, A.2
-
30
-
-
0032508585
-
Expression cloning and characterization of a transporter for large neutral amino acids activated by the heavy chain of 4F2 antigen (CD98)
-
Kanai Y., Segawa H., Miyamoto K., Uchino H., Takeda E., and Endou H. Expression cloning and characterization of a transporter for large neutral amino acids activated by the heavy chain of 4F2 antigen (CD98). J. Biol. Chem. 273 (1998) 23629-23632
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 23629-23632
-
-
Kanai, Y.1
Segawa, H.2
Miyamoto, K.3
Uchino, H.4
Takeda, E.5
Endou, H.6
-
31
-
-
0037178786
-
mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery
-
Kim D.H., Sarbassov D.D., Ali S.M., King J.E., Latek R.R., Erdjument-Bromage H., Tempst P., and Sabatini D.M. mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery. Cell 110 (2002) 163-175
-
(2002)
Cell
, vol.110
, pp. 163-175
-
-
Kim, D.H.1
Sarbassov, D.D.2
Ali, S.M.3
King, J.E.4
Latek, R.R.5
Erdjument-Bromage, H.6
Tempst, P.7
Sabatini, D.M.8
-
32
-
-
48649085816
-
Regulation of TORC1 by Rag GTPases in nutrient response
-
Kim E., Goraksha-Hicks P., Li L., Neufeld T.P., and Guan K.L. Regulation of TORC1 by Rag GTPases in nutrient response. Nat. Cell Biol. 10 (2008) 935-945
-
(2008)
Nat. Cell Biol.
, vol.10
, pp. 935-945
-
-
Kim, E.1
Goraksha-Hicks, P.2
Li, L.3
Neufeld, T.P.4
Guan, K.L.5
-
33
-
-
34548077575
-
Dissection of the autophagosome maturation process by a novel reporter protein, tandem fluorescent-tagged LC3
-
Kimura S., Noda T., and Yoshimori T. Dissection of the autophagosome maturation process by a novel reporter protein, tandem fluorescent-tagged LC3. Autophagy 3 (2007) 452-460
-
(2007)
Autophagy
, vol.3
, pp. 452-460
-
-
Kimura, S.1
Noda, T.2
Yoshimori, T.3
-
34
-
-
0015288919
-
The role of glutamine in the oxidative metabolism of malignant cells
-
Kovacevic Z., and Morris H.P. The role of glutamine in the oxidative metabolism of malignant cells. Cancer Res. 32 (1972) 326-333
-
(1972)
Cancer Res.
, vol.32
, pp. 326-333
-
-
Kovacevic, Z.1
Morris, H.P.2
-
35
-
-
3042701853
-
Platelet-derived growth factor stimulates LAT1 gene expression in vascular smooth muscle: role in cell growth
-
Liu X.M., Reyna S.V., Ensenat D., Peyton K.J., Wang H., Schafer A.I., and Durante W. Platelet-derived growth factor stimulates LAT1 gene expression in vascular smooth muscle: role in cell growth. FASEB J. 18 (2004) 768-770
-
(2004)
FASEB J.
, vol.18
, pp. 768-770
-
-
Liu, X.M.1
Reyna, S.V.2
Ensenat, D.3
Peyton, K.J.4
Wang, H.5
Schafer, A.I.6
Durante, W.7
-
36
-
-
41949101770
-
SKAR links pre-mRNA splicing to mTOR/S6K1-mediated enhanced translation efficiency of spliced mRNAs
-
Ma X.M., Yoon S.O., Richardson C.J., Julich K., and Blenis J. SKAR links pre-mRNA splicing to mTOR/S6K1-mediated enhanced translation efficiency of spliced mRNAs. Cell 133 (2008) 303-313
-
(2008)
Cell
, vol.133
, pp. 303-313
-
-
Ma, X.M.1
Yoon, S.O.2
Richardson, C.J.3
Julich, K.4
Blenis, J.5
-
37
-
-
0034176584
-
minidiscs encodes a putative amino acid transporter subunit required non-autonomously for imaginal cell proliferation
-
Martin J.F., Hersperger E., Simcox A., and Shearn A. minidiscs encodes a putative amino acid transporter subunit required non-autonomously for imaginal cell proliferation. Mech. Dev. 92 (2000) 155-167
-
(2000)
Mech. Dev.
, vol.92
, pp. 155-167
-
-
Martin, J.F.1
Hersperger, E.2
Simcox, A.3
Shearn, A.4
-
38
-
-
0036385637
-
Coordinate regulation of translation by the PI 3-kinase and mTOR pathways
-
Martin K.A., and Blenis J. Coordinate regulation of translation by the PI 3-kinase and mTOR pathways. Adv. Cancer Res. 86 (2002) 1-39
-
(2002)
Adv. Cancer Res.
, vol.86
, pp. 1-39
-
-
Martin, K.A.1
Blenis, J.2
-
39
-
-
0032541636
-
Amino-acid transport by heterodimers of 4F2hc/CD98 and members of a permease family
-
Mastroberardino L., Spindler B., Pfeiffer R., Skelly P.J., Loffing J., Shoemaker C.B., and Verrey F. Amino-acid transport by heterodimers of 4F2hc/CD98 and members of a permease family. Nature 395 (1998) 288-291
-
(1998)
Nature
, vol.395
, pp. 288-291
-
-
Mastroberardino, L.1
Spindler, B.2
Pfeiffer, R.3
Skelly, P.J.4
Loffing, J.5
Shoemaker, C.B.6
Verrey, F.7
-
40
-
-
34249803325
-
The transport of glutamine into mammalian cells
-
McGivan J.D., and Bungard C.I. The transport of glutamine into mammalian cells. Front. Biosci. 12 (2007) 874-882
-
(2007)
Front. Biosci.
, vol.12
, pp. 874-882
-
-
McGivan, J.D.1
Bungard, C.I.2
-
41
-
-
0037083854
-
Activation of system L heterodimeric amino acid exchangers by intracellular substrates
-
Meier C., Ristic Z., Klauser S., and Verrey F. Activation of system L heterodimeric amino acid exchangers by intracellular substrates. EMBO J. 21 (2002) 580-589
-
(2002)
EMBO J.
, vol.21
, pp. 580-589
-
-
Meier, C.1
Ristic, Z.2
Klauser, S.3
Verrey, F.4
-
43
-
-
39849109338
-
Autophagy fights disease through cellular self-digestion
-
Mizushima N., Levine B., Cuervo A.M., and Klionsky D.J. Autophagy fights disease through cellular self-digestion. Nature 451 (2008) 1069-1075
-
(2008)
Nature
, vol.451
, pp. 1069-1075
-
-
Mizushima, N.1
Levine, B.2
Cuervo, A.M.3
Klionsky, D.J.4
-
44
-
-
0035884416
-
Molecular events involved in up-regulating human Na+-independent neutral amino acid transporter LAT1 during T-cell activation
-
Nii T., Segawa H., Taketani Y., Tani Y., Ohkido M., Kishida S., Ito M., Endou H., Kanai Y., Takeda E., et al. Molecular events involved in up-regulating human Na+-independent neutral amino acid transporter LAT1 during T-cell activation. Biochem. J. 358 (2001) 693-704
-
(2001)
Biochem. J.
, vol.358
, pp. 693-704
-
-
Nii, T.1
Segawa, H.2
Taketani, Y.3
Tani, Y.4
Ohkido, M.5
Kishida, S.6
Ito, M.7
Endou, H.8
Kanai, Y.9
Takeda, E.10
-
45
-
-
20044392290
-
Atrophy of S6K1(-/-) skeletal muscle cells reveals distinct mTOR effectors for cell cycle and size control
-
Ohanna M., Sobering A.K., Lapointe T., Lorenzo L., Praud C., Petroulakis E., Sonenberg N., Kelly P.A., Sotiropoulos A., and Pende M. Atrophy of S6K1(-/-) skeletal muscle cells reveals distinct mTOR effectors for cell cycle and size control. Nat. Cell Biol. 7 (2005) 286-294
-
(2005)
Nat. Cell Biol.
, vol.7
, pp. 286-294
-
-
Ohanna, M.1
Sobering, A.K.2
Lapointe, T.3
Lorenzo, L.4
Praud, C.5
Petroulakis, E.6
Sonenberg, N.7
Kelly, P.A.8
Sotiropoulos, A.9
Pende, M.10
-
46
-
-
0018386209
-
Evidence that glutamine, not sugar, is the major energy source for cultured HeLa cells
-
Reitzer L.J., Wice B.M., and Kennell D. Evidence that glutamine, not sugar, is the major energy source for cultured HeLa cells. J. Biol. Chem. 254 (1979) 2669-2676
-
(1979)
J. Biol. Chem.
, vol.254
, pp. 2669-2676
-
-
Reitzer, L.J.1
Wice, B.M.2
Kennell, D.3
-
47
-
-
45849105156
-
The Rag GTPases Bind Raptor and Mediate Amino Acid Signaling to mTORC1
-
Sancak Y., Peterson T.R., Shaul Y.D., Lindquist R.A., Thoreen C.C., Bar-Peled L., and Sabatini D.M. The Rag GTPases Bind Raptor and Mediate Amino Acid Signaling to mTORC1. Science 320 (2008) 1496-1501
-
(2008)
Science
, vol.320
, pp. 1496-1501
-
-
Sancak, Y.1
Peterson, T.R.2
Shaul, Y.D.3
Lindquist, R.A.4
Thoreen, C.C.5
Bar-Peled, L.6
Sabatini, D.M.7
-
48
-
-
3342895823
-
Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton
-
Sarbassov D.D., Ali S.M., Kim D.H., Guertin D.A., Latek R.R., Erdjument-Bromage H., Tempst P., and Sabatini D.M. Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton. Curr. Biol. 14 (2004) 1296-1302
-
(2004)
Curr. Biol.
, vol.14
, pp. 1296-1302
-
-
Sarbassov, D.D.1
Ali, S.M.2
Kim, D.H.3
Guertin, D.A.4
Latek, R.R.5
Erdjument-Bromage, H.6
Tempst, P.7
Sabatini, D.M.8
-
50
-
-
0033538560
-
Identification and functional characterization of a Na+-independent neutral amino acid transporter with broad substrate selectivity
-
Segawa H., Fukasawa Y., Miyamoto K., Takeda E., Endou H., and Kanai Y. Identification and functional characterization of a Na+-independent neutral amino acid transporter with broad substrate selectivity. J. Biol. Chem. 274 (1999) 19745-19751
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 19745-19751
-
-
Segawa, H.1
Fukasawa, Y.2
Miyamoto, K.3
Takeda, E.4
Endou, H.5
Kanai, Y.6
-
51
-
-
33745307617
-
Ras, PI(3)K and mTOR signalling controls tumour cell growth
-
Shaw R.J., and Cantley L.C. Ras, PI(3)K and mTOR signalling controls tumour cell growth. Nature 441 (2006) 424-430
-
(2006)
Nature
, vol.441
, pp. 424-430
-
-
Shaw, R.J.1
Cantley, L.C.2
-
52
-
-
21244480367
-
The tuberous sclerosis protein TSC2 is not required for the regulation of the mammalian target of rapamycin by amino acids and certain cellular stresses
-
Smith E.M., Finn S.G., Tee A.R., Browne G.J., and Proud C.G. The tuberous sclerosis protein TSC2 is not required for the regulation of the mammalian target of rapamycin by amino acids and certain cellular stresses. J. Biol. Chem. 280 (2005) 18717-18727
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 18717-18727
-
-
Smith, E.M.1
Finn, S.G.2
Tee, A.R.3
Browne, G.J.4
Proud, C.G.5
-
53
-
-
0026668042
-
Autophagy in yeast demonstrated with proteinase-deficient mutants and conditions for its induction
-
Takeshige K., Baba M., Tsuboi S., Noda T., and Ohsumi Y. Autophagy in yeast demonstrated with proteinase-deficient mutants and conditions for its induction. J. Cell Biol. 119 (1992) 301-311
-
(1992)
J. Cell Biol.
, vol.119
, pp. 301-311
-
-
Takeshige, K.1
Baba, M.2
Tsuboi, S.3
Noda, T.4
Ohsumi, Y.5
-
54
-
-
0029888341
-
Cloning and functional characterization of a system ASC-like Na+-dependent neutral amino acid transporter
-
Utsunomiya-Tate N., Endou H., and Kanai Y. Cloning and functional characterization of a system ASC-like Na+-dependent neutral amino acid transporter. J. Biol. Chem. 271 (1996) 14883-14890
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 14883-14890
-
-
Utsunomiya-Tate, N.1
Endou, H.2
Kanai, Y.3
-
55
-
-
0037291723
-
System L: heteromeric exchangers of large, neutral amino acids involved in directional transport
-
Verrey F. System L: heteromeric exchangers of large, neutral amino acids involved in directional transport. Pflugers Arch. 445 (2003) 529-533
-
(2003)
Pflugers Arch.
, vol.445
, pp. 529-533
-
-
Verrey, F.1
-
56
-
-
0032528917
-
Amino acid availability regulates p70 S6 kinase and multiple translation factors
-
Wang X., Campbell L.E., Miller C.M., and Proud C.G. Amino acid availability regulates p70 S6 kinase and multiple translation factors. Biochem. J. 334 (1998) 261-267
-
(1998)
Biochem. J.
, vol.334
, pp. 261-267
-
-
Wang, X.1
Campbell, L.E.2
Miller, C.M.3
Proud, C.G.4
-
57
-
-
0029904540
-
Expression of a highly conserved oncofetal gene, TA1/E16, in human colon carcinoma and other primary cancers: homology to Schistosoma mansoni amino acid permease and Caenorhabditis elegans gene products
-
Wolf D.A., Wang S., Panzica M.A., Bassily N.H., and Thompson N.L. Expression of a highly conserved oncofetal gene, TA1/E16, in human colon carcinoma and other primary cancers: homology to Schistosoma mansoni amino acid permease and Caenorhabditis elegans gene products. Cancer Res. 56 (1996) 5012-5022
-
(1996)
Cancer Res.
, vol.56
, pp. 5012-5022
-
-
Wolf, D.A.1
Wang, S.2
Panzica, M.A.3
Bassily, N.H.4
Thompson, N.L.5
-
58
-
-
32044465506
-
TOR signaling in growth and metabolism
-
Wullschleger S., Loewith R., and Hall M.N. TOR signaling in growth and metabolism. Cell 124 (2006) 471-484
-
(2006)
Cell
, vol.124
, pp. 471-484
-
-
Wullschleger, S.1
Loewith, R.2
Hall, M.N.3
-
59
-
-
4243389920
-
Human L-type amino acid transporter 1 (LAT1): characterization of function and expression in tumor cell lines
-
Yanagida O., Kanai Y., Chairoungdua A., Kim D.K., Segawa H., Nii T., Cha S.H., Matsuo H., Fukushima J., Fukasawa Y., et al. Human L-type amino acid transporter 1 (LAT1): characterization of function and expression in tumor cell lines. Biochim. Biophys. Acta 1514 (2001) 291-302
-
(2001)
Biochim. Biophys. Acta
, vol.1514
, pp. 291-302
-
-
Yanagida, O.1
Kanai, Y.2
Chairoungdua, A.3
Kim, D.K.4
Segawa, H.5
Nii, T.6
Cha, S.H.7
Matsuo, H.8
Fukushima, J.9
Fukasawa, Y.10
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