The tuberous sclerosis protein TSC2 is not required for the regulation of the mammalian target of rapamycin by amino acids and certain cellular stresses

Journal of Biological Chemistry

Volumn 280, Issue 19, 2005, Pages 18717-18727

  Smith, Ewan M ^a   Finn, Stephen G ^a   Tee, Andrew R ^a   Brownei, Gareth J ^a,b   Proud, Christopher G ^a,c  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

^b UNIVERSITY OF LEICESTER   (United Kingdom)

^c UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ANALYSIS; AMINO ACIDS; CELLS; ENZYMES; HYDROGEN PEROXIDE; HYDROLYSIS; INSULIN;

CELL STRESSES; GTPASE-ACTIVATOR DOMAIN; MAMMALIAN TARGET OF RAPAMYCIN (MTOR); PROTEIN SYNTHESIS;

PROTEINS;

5 AMINO 4 IMIDAZOLECARBOXAMIDE RIBOSIDE; AMINO ACID; ARSENIC TRIOXIDE; CYCLOHEXIMIDE; DEOXYGLUCOSE; ELONGATION FACTOR 2; GUANOSINE DIPHOSPHATE; GUANOSINE TRIPHOSPHATE; HYDROGEN PEROXIDE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; MAMMALIAN TARGET OF RAPAMYCIN; SORBITOL; TUBERIN; 5' AMP ACTIVATED PROTEIN KINASE; 5'-AMP-ACTIVATED PROTEIN KINASE; ADENOSINE TRIPHOSPHATE; CALMODULIN DEPENDENT PROTEIN KINASE III; CALMODULIN-DEPENDENT PROTEIN KINASE III; CARRIER PROTEIN; EIF4EBP1 PROTEIN, HUMAN; EIF4EBP1 PROTEIN, MOUSE; GLUCOSE; GUANINE; MONOMERIC GUANINE NUCLEOTIDE BINDING PROTEIN; MULTIENZYME COMPLEX; NEUROPEPTIDE; PHOSPHOPROTEIN; PROTEIN KINASE; PROTEIN KINASE (CALCIUM,CALMODULIN); PROTEIN S6; PROTEIN SERINE THREONINE KINASE; PROTEIN SYNTHESIS INHIBITOR; REPRESSOR PROTEIN; RHEB PROTEIN, MOUSE; SIGNAL TRANSDUCING ADAPTOR PROTEIN; TUMOR SUPPRESSOR PROTEIN;

ANIMAL CELL; ARTICLE; EMBRYO; FIBROBLAST CULTURE; IMMUNOPRECIPITATION; MOUSE; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RNA TRANSLATION; SIGNAL TRANSDUCTION; STRESS; ANIMAL; BIOLOGICAL MODEL; CELL CULTURE; CELL LINE; CHEMISTRY; DOSE RESPONSE; FIBROBLAST; GENE EXPRESSION REGULATION; HUMAN; HYDROLYSIS; IMMUNOBLOTTING; METABOLISM; MUTATION; PHOSPHORYLATION; PHYSIOLOGY; PROTEIN TERTIARY STRUCTURE; TIME; TRANSGENE;

EUKARYOTA; MAMMALIA;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADENOSINE TRIPHOSPHATE; AMINO ACIDS; ANIMALS; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CARRIER PROTEINS; CELL LINE; CELLS, CULTURED; CYCLOHEXIMIDE; DOSE-RESPONSE RELATIONSHIP, DRUG; FIBROBLASTS; GENE EXPRESSION REGULATION; GLUCOSE; GUANINE; GUANOSINE DIPHOSPHATE; GUANOSINE TRIPHOSPHATE; HUMANS; HYDROGEN PEROXIDE; HYDROLYSIS; IMMUNOBLOTTING; IMMUNOPRECIPITATION; MICE; MODELS, BIOLOGICAL; MONOMERIC GTP-BINDING PROTEINS; MULTIENZYME COMPLEXES; MUTATION; NEUROPEPTIDES; PHOSPHOPROTEINS; PHOSPHORYLATION; PROTEIN KINASES; PROTEIN STRUCTURE, TERTIARY; PROTEIN SYNTHESIS INHIBITORS; PROTEIN-SERINE-THREONINE KINASES; REPRESSOR PROTEINS; RIBOSOMAL PROTEIN S6; SIGNAL TRANSDUCTION; SORBITOL; TIME FACTORS; TRANSGENES; TUMOR SUPPRESSOR PROTEINS;

EID: 21244480367     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M414499200     Document Type: Article

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