-
1
-
-
0030941803
-
The SREBP pathway: Regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor
-
(1997)
Cell
, vol.89
, pp. 331-340
-
-
Brown, M.S.1
Goldstein, J.L.2
-
9
-
-
0029797604
-
Overproduction of cholesterol and fatty acids causes massive liver enlargement in transgenic mice expressing truncated SREBP-1a
-
(1996)
J. Clin. Invest.
, vol.98
, pp. 1575-1584
-
-
Shimano, H.1
-
10
-
-
0030907175
-
Isoform 1c of sterol regulatory element binding protein is less active than isoform 1a in livers of transgenic mice and in cultured cells
-
(1997)
J. Clin. Invest.
, vol.99
, pp. 846-854
-
-
Shimano, H.1
-
11
-
-
0032104180
-
Activation of cholesterol synthesis in preference to fatty acid synthesis in liver and adipose tissue of transgenic mice over-producing sterol regulatory element-binding protein-2
-
(1998)
J. Clin. Invest.
, vol.101
, pp. 2331-2339
-
-
Horton, J.D.1
-
12
-
-
0032535089
-
Blunted feedback suppression of SREBP processing by dietary cholesterol in transgenic mice expressing sterol-resistant SCAP(D443N)
-
(1998)
J. Clin. Invest.
, vol.102
, pp. 2050-2060
-
-
Korn, B.S.1
-
13
-
-
0030829812
-
Elevated levels of SREBP-2 and cholesterol synthesis in livers of mice homozygous for a targeted disruption of the SREBP-1 gene
-
(1997)
J. Clin. Invest.
, vol.100
, pp. 2115-2124
-
-
Shimano, H.1
-
14
-
-
0035873619
-
SREBP cleavage-activating protein (SCAP) is required for increased lipid synthesis in liver induced by cholesterol deprivation and insulin elevation
-
(2001)
Genes Dev.
, vol.15
, pp. 1206-1216
-
-
Matsuda, M.1
-
16
-
-
0037088683
-
Diminished hepatic response to fasting/refeeding and liver X receptor agonists in mice with selective deficiency of sterol regulatory element-binding protein-1c
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 9520-9528
-
-
Liang, G.1
-
17
-
-
0034931033
-
Functional analysis of secreted and trans-membrane proteins critical to mouse development
-
(2001)
Nat. Genet.
, vol.28
, pp. 241-249
-
-
Mitchell, K.J.1
-
20
-
-
0029958652
-
Sterol-dependent transcriptional regulation of sterol regulatory element-binding protein-2
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 26461-26464
-
-
Sato, R.1
-
21
-
-
0034613175
-
Promoter analysis of the mouse sterol regulatory element-binding protein-1c gene
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 31078-31085
-
-
Amemiya-Kudo, M.1
-
23
-
-
0034669025
-
Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRα and LXRβ
-
(2000)
Genes Dev.
, vol.14
, pp. 2819-2830
-
-
Repa, J.J.1
-
26
-
-
0035932990
-
Unsaturated fatty acids inhibit transcription of the sterol regulatory element-binding protein-1c (SREBP-1c) gene by antagonizing ligand-dependent activation of the LXR
-
(2001)
Proc Natl. Acad. Sci. USA
, vol.98
, pp. 6027-6032
-
-
Ou, J.1
-
30
-
-
0032933626
-
ADD1/SREBP-1c is requited in the activation of hepatic lipogenic gene expression by glucose
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 3760-3768
-
-
Foretz, M.1
-
31
-
-
0033636780
-
Decreased IRS-2 and increased SREBP-1c lead to mixed insulin resistance and sensitivity in livers oflipodystrophic and ob/ob mice
-
(2000)
Mol. Cell
, vol.6
, pp. 77-86
-
-
Shimomura, I.1
-
33
-
-
0031963963
-
Nutritional and insulin regulation of fatty acid synthetase and leptin gene expression through ADD1/SREBP1
-
(1998)
J. Clin. Invest.
, vol.101
, pp. 1-9
-
-
Kim, J.B.1
-
34
-
-
0033544940
-
Sterol regulatory element-binding protein-1 as a key transcription factor for nutritional induction of lipogenic enzyme genes
-
(1999)
J Biol. Chem.
, vol.274
, pp. 35832-35839
-
-
Shimano, H.1
-
35
-
-
0035514942
-
Adenovirus-mediated overexpression ofsterol regulatory element binding protein-1c mimics insulin effects on hepatic gene expression and glucose homeostasis in diabetic mice
-
(2001)
Diabetes
, vol.50
, pp. 2425-2430
-
-
Becard, D.1
-
36
-
-
0035860743
-
Sterol regulatory element-binding proteinic mimics the negative effect of insulin on phosphoenolpyruvate carboxykinase (GTP) gene transcription
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 34816-34823
-
-
Chakravarty, K.1
-
40
-
-
0012785395
-
Metformin reverses fatty liver disease in obese, leptin-deficient mice
-
(2000)
Nat. Med.
, vol.6
, pp. 998-1003
-
-
Lin, H.Z.1
-
41
-
-
0034773404
-
Role of AMP-activated protein kinase in mechanism of metformin action
-
DOI:10.1172/JCI200113505
-
(2001)
J. Clin. Invest.
, vol.108
, pp. 1167-1174
-
-
Zhou, G.1
-
46
-
-
0037192797
-
Direct and indirect mechanisms for regulation of fatty acid synthase gene expression by LXRs
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 11019-11025
-
-
Joseph, S.B.1
|