-
1
-
-
59249091114
-
Effect of testosterone on insulin stimulated IRS1 Ser phosphorylation in primary rat myotubes - A potential model for PCOS-related insulin resistance
-
Allemand MC, Irving BA, Asmann YW, Klaus KA, Tatpati L, Coddington CC & Nair KS 2009 Effect of testosterone on insulin stimulated IRS1 Ser phosphorylation in primary rat myotubes - a potential model for PCOS-related insulin resistance. PLoS ONE 4 e4274.
-
(2009)
PLoS ONE
, vol.4
-
-
Allemand, M.C.1
Irving, B.A.2
Asmann, Y.W.3
Klaus, K.A.4
Tatpati, L.5
Coddington, C.C.6
Nair, K.S.7
-
2
-
-
18144386162
-
Selective activation of AMPK-PGC-1α or PKB-TSC2-mTOR signaling can explain specific adaptive responses to endurance or resistance training-like electrical muscle stimulation
-
DOI 10.1096/04-2179fje
-
Atherton PJ, Babraj J, Smith K, Singh J, Rennie MJ & Wackerhage H 2005 Selective activation of AMPK-PGC-1α or PKB-TSC2-mTOR signaling can explain specific adaptive responses to endurance or resistance training-like electrical muscle stimulation. FASEB Journal 19 786-788. (Pubitemid 40617384)
-
(2005)
FASEB Journal
, vol.19
, Issue.7
, pp. 786-788
-
-
Atherton, P.J.1
Babraj, J.2
Smith, K.3
Singh, J.4
Rennie, M.J.5
Wackerhage, H.6
-
3
-
-
0031919552
-
Insulin signal transduction through protein kinase cascades
-
DOI 10.1023/A:1006823109415
-
Avruch J 1998 Insulin signal transduction through protein kinase cascades. Molecular and Cellular Biochemistry 182 31-48. (Pubitemid 28181646)
-
(1998)
Molecular and Cellular Biochemistry
, vol.182
, Issue.1-2
, pp. 31-48
-
-
Avruch, J.1
-
4
-
-
0026490523
-
Regulation of glucose transport in skeletal muscle
-
Barnard RJ & Youngren JF 1992 Regulation of glucose transport in skeletal muscle. FASEB Journal 6 3238-3244.
-
(1992)
FASEB Journal
, vol.6
, pp. 3238-3244
-
-
Barnard, R.J.1
Youngren, J.F.2
-
6
-
-
0036725464
-
Interaction between free fatty acids and glucose metabolism
-
DOI 10.1097/00075197-200209000-00014
-
Boden G 2002 Interaction between free fatty acids and glucose metabolism. Current Opinion in Clinical Nutrition and Metabolic Care 5 545-549. (Pubitemid 40684651)
-
(2002)
Current Opinion in Clinical Nutrition and Metabolic Care
, vol.5
, Issue.5
, pp. 545-549
-
-
Boden, G.1
-
7
-
-
0037025356
-
AMP-activated protein kinase suppresses protein synthesis in rat skeletal muscle through down-regulated mammalian target of rapamycin (mTOR) signaling
-
doi: 10.1074/jbc.C200171200
-
Bolster DR, Crozier SJ, Kimball SR & Jefferson LS 2002 AMP-activated protein kinase suppresses protein synthesis in rat skeletal muscle through down-regulated mammalian target of rapamycin (mTOR) signaling. Journal of Biological Chemistry 277 23977-23980 (doi: 10.1074/jbc.C200171200).
-
(2002)
Journal of Biological Chemistry
, vol.277
, pp. 23977-23980
-
-
Bolster, D.R.1
Crozier, S.J.2
Kimball, S.R.3
Jefferson, L.S.4
-
8
-
-
21844468767
-
Phosphorylation of mammalian target of rapamycin (mTOR) at Ser-2448 is mediated by p70S6 kinase
-
Chiang GG & Abraham RT 2005 Phosphorylation of mammalian target of rapamycin (mTOR) at Ser-2448 is mediated by p70S6 kinase. Journal of Biological Chemistry 280 25485-25490.
-
(2005)
Journal of Biological Chemistry
, vol.280
, pp. 25485-25490
-
-
Chiang, G.G.1
Abraham, R.T.2
-
9
-
-
0035914388
-
Akt1/PKBa Is Required for Normal Growth but Dispensable for Maintenance of Glucose Homeostasis in Mice
-
DOI 10.1074/jbc.C100462200
-
Cho H, Thorvaldsen JL, Chu Q, Feng F & Birnbaum MJ 2001 Akt1/PKBa is required for normal growth but dispensable for maintenance of glucose homeostasis in mice. Journal of Biological Chemistry 276 38349-38352. (Pubitemid 37371183)
-
(2001)
Journal of Biological Chemistry
, vol.276
, Issue.42
, pp. 38349-38352
-
-
Cho, H.1
Thorvaldsen, J.L.2
Chu, Q.3
Feng, F.4
Birnbaum, M.J.5
-
10
-
-
34548371839
-
The molecular bases of training adaptation
-
Coffey VG & Hawley JA 2007 The molecular bases of training adaptation. Sports Medicine 37 737-763.
-
(2007)
Sports Medicine
, vol.37
, pp. 737-763
-
-
Coffey, V.G.1
Hawley, J.A.2
-
11
-
-
30744439347
-
Early signaling responses to divergent exercise stimuli in skeletal muscle from well-trained humans
-
DOI 10.1096/fj.05-4809fje
-
Coffey VG, Zhong Z, Shield A, Canny BJ, Chibalin AV, Zierath JR & Hawley JA 2006 Early signaling responses to divergent exercise stimuli in skeletal muscle from well-trained humans. FASEB Journal 20 190-192. (Pubitemid 43100510)
-
(2006)
FASEB Journal
, vol.20
, Issue.1
, pp. 190-192
-
-
Coffey, V.G.1
Zhong, Z.2
Shield, A.3
Canny, B.J.4
Chibalin, A.V.5
Zierath, J.R.6
Hawley, J.A.7
-
12
-
-
43049098240
-
Role of adenosine 5′-monophosphate-activated protein kinase subunits in skeletal muscle mammalian target of rapamycin signaling
-
DOI 10.1210/me.2007-0448
-
Deshmukh AS, Treebak JT, Long YC, Viollet B, Wojtaszewski JF & Zierath JR 2008 Role of adenosine 5′-monophosphate-activated protein kinase subunits in skeletal muscle mammalian target of rapamycin signaling. Molecular Endocrinology 22 1105-1112. (Pubitemid 351629611)
-
(2008)
Molecular Endocrinology
, vol.22
, Issue.5
, pp. 1105-1112
-
-
Deshmukh, A.S.1
Treebak, J.T.2
Yun, C.L.3
Viollet, B.4
Wojtaszewski, J.F.P.5
Zierath, J.R.6
-
13
-
-
34249678700
-
Aerobic exercise overcomes the age-related insulin resistance of muscle protein metabolism by improving endothelial function and Akt/mammalian target of rapamycin signaling
-
DOI 10.2337/db06-1566
-
Fujita S, Rasmussen BB, Cadenas JG, Drummond MJ, Glynn EL, Sattler FR & Volpi E 2007 Aerobic exercise overcomes the age-related insulin resistance of muscle protein metabolism by improving endothelial function and Akt/mammalian target of rapamycin signaling. Diabetes 56 1615-1622. (Pubitemid 46842620)
-
(2007)
Diabetes
, vol.56
, Issue.6
, pp. 1615-1622
-
-
Fujita, S.1
Rasmussen, B.B.2
Cadenas, J.G.3
Drummond, M.J.4
Glynn, E.L.5
Sattler, F.R.6
Volpi, E.7
-
14
-
-
39749190584
-
A chronic increase in physical activity inhibits fed-state mTOR/S6K1 signaling and reduces IRS-1 serine phosphorylation in rat skeletal muscle
-
Glynn EL, Lujan HL, Kramer VJ, Drummond MJ, DiCarlo SE & Rasmussen BB 2008 A chronic increase in physical activity inhibits fed-state mTOR/S6K1 signaling and reduces IRS-1 serine phosphorylation in rat skeletal muscle. Applied Physiology, Nutrition, and Metabolism 33 93-101.
-
(2008)
Applied Physiology, Nutrition, and Metabolism
, vol.33
, pp. 93-101
-
-
Glynn, E.L.1
Lujan, H.L.2
Kramer, V.J.3
Drummond, M.J.4
Dicarlo, S.E.5
Rasmussen, B.B.6
-
15
-
-
4644235275
-
Exercise as a therapeutic intervention for the prevention and treatment of insulin resistance
-
Hawley JA 2004 Exercise as a therapeutic intervention for the prevention and treatment of insulin resistance. Diabetes/Metabolism Research and Reviews 20 383-393.
-
(2004)
Diabetes/Metabolism Research and Reviews
, vol.20
, pp. 383-393
-
-
Hawley, J.A.1
-
16
-
-
37249066135
-
Exercise training-induced improvements in insulin action
-
Hawley JA & Lessard SJ 2008 Exercise training-induced improvements in insulin action. Acta Physiologica 192 127-135.
-
(2008)
Acta Physiologica
, vol.192
, pp. 127-135
-
-
Hawley, J.A.1
Lessard, S.J.2
-
17
-
-
33847652276
-
Signalling mechanisms in skeletal muscle: Role in substrate selection and muscle adaptation
-
Hawley JA, Hargreaves M & Zierath JR 2006 Signalling mechanisms in skeletal muscle: role in substrate selection and muscle adaptation. Essays in Biochemistry 42 1-12.
-
(2006)
Essays in Biochemistry
, vol.42
, pp. 1-12
-
-
Hawley, J.A.1
Hargreaves, M.2
Zierath, J.R.3
-
18
-
-
28844434558
-
mTOR.RICTOR is the Ser473 kinase for Akt/protein kinase B in 3T3-L1 adipocytes
-
Hresko RC & Mueckler M 2005 mTOR.RICTOR is the Ser473 kinase for Akt/protein kinase B in 3T3-L1 adipocytes. Journal of Biological Chemistry 280 40406-40416.
-
(2005)
Journal of Biological Chemistry
, vol.280
, pp. 40406-40416
-
-
Hresko, R.C.1
Mueckler, M.2
-
19
-
-
7944235758
-
Mammalian TOR, complex 2 controls the actin cytoskeleton and is rapamycin insensitive
-
Jacinto E, Loewith R, Schmidt A, Lin S, Ruegg MA, Hall A & Hall MN 2004 Mammalian TOR, complex 2 controls the actin cytoskeleton and is rapamycin insensitive. Nature Cell Biology 6 1122-1128.
-
(2004)
Nature Cell Biology
, vol.6
, pp. 1122-1128
-
-
Jacinto, E.1
Loewith, R.2
Schmidt, A.3
Lin, S.4
Ruegg, M.A.5
Hall, A.6
Hall, M.N.7
-
20
-
-
33846330586
-
Potentiation of insulin-stimulated glucose transport by the AMP-activated protein kinase
-
Ju JS, Gitcho MA, Casmaer CA, Patil PB, Han D-G, Spencer SA & Fisher JS 2007 Potentiation of insulin-stimulated glucose transport by the AMP-activated protein kinase. American Journal of Physiology. Cell Physiology 292 C564-C572.
-
(2007)
American Journal of Physiology. Cell Physiology
, vol.292
-
-
Ju, J.S.1
Gitcho, M.A.2
Casmaer, C.A.3
Patil, P.B.4
Han, D.-G.5
Spencer, S.A.6
Fisher, J.S.7
-
21
-
-
14244256097
-
Increased activation of the mammalian target of rapamycin pathway in liver and skeletal muscle of obese rats: Possible involvement in obesity-linked insulin resistance
-
DOI 10.1210/en.2004-0921
-
Khamzina L, Veilleux A, Bergeron S & Marette A 2005 Increased activation of the mammalian target of rapamycin pathway in liver and skeletal muscle of obese rats: possible involvement in obesity-linked insulin resistance. Endocrinology 146 1473-1481. (Pubitemid 40289337)
-
(2005)
Endocrinology
, vol.146
, Issue.3
, pp. 1473-1481
-
-
Khamzina, L.1
Veilleux, A.2
Bergeron, S.3
Marette, A.4
-
22
-
-
0037178786
-
MTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery
-
DOI 10.1016/S0092-8674(02)00808-5
-
Kim D-H, Sarbassov DD, Ali SM, King JE, Latek RR, Erdjument-Bromage H, Tempst P & Sabatini DM 2002 mTOR interacts with Raptor to form a nutrient-sensitive complex that signals to the cell growth machinery. Cell 110 163-175. (Pubitemid 34876545)
-
(2002)
Cell
, vol.110
, Issue.2
, pp. 163-175
-
-
Kim, D.-H.1
Sarbassov, D.D.2
Ali, S.M.3
King, J.E.4
Latek, R.R.5
Erdjument-Bromage, H.6
Tempst, P.7
Sabatini, D.M.8
-
23
-
-
33750718800
-
Interaction between the AMP-activated protein kinase and mTOR signaling pathways
-
Kimball SR 2006 Interaction between the AMP-activated protein kinase and mTOR signaling pathways. Medicine and Science in Sports and Exercise 11 1958-1964.
-
(2006)
Medicine and Science in Sports and Exercise
, vol.11
, pp. 1958-1964
-
-
Kimball, S.R.1
-
24
-
-
0036720367
-
Exercise effects on muscle insulin signaling and action: Invited review: role of insulin in translational control of protein synthesis in skeletal muscle by amino acids or exercise
-
Kimball SR, Farrell PA & Jefferson LS 2002 Exercise effects on muscle insulin signaling and action: invited review: role of insulin in translational control of protein synthesis in skeletal muscle by amino acids or exercise. Journal of Applied Physiology 93 1168-1180.
-
(2002)
Journal of Applied Physiology
, vol.93
, pp. 1168-1180
-
-
Kimball, S.R.1
Farrell, P.A.2
Jefferson, L.S.3
-
25
-
-
34249679233
-
The mammalian target of rapamycin pathway regulates nutrient-sensitive glucose uptake in man
-
DOI 10.2337/db06-1016
-
Krebs M, Brunmair B, Brehm A, Artwohl M, Szendroedi J, Nowotny P, Roth E, Furnsinn C, Promintzer M, Anderwald C et al. 2007 The mammalian target of rapamycin pathway regulates nutrient-sensitive glucose uptake in man. Diabetes 56 1600-1607. (Pubitemid 46842618)
-
(2007)
Diabetes
, vol.56
, Issue.6
, pp. 1600-1607
-
-
Krebs, M.1
Brunmair, B.2
Brehm, A.3
Artwohl, M.4
Szendroedi, J.5
Nowotny, P.6
Roth, E.7
Furnsinn, C.8
Promintzer, M.9
Anderwald, C.10
Bischof, M.11
Roden, M.12
-
26
-
-
37549000623
-
Muscle-specific deletion of rictor impairs insulin-stimulated glucose transport and enhances basal glycogen synthase activity
-
Kumar A, Harris TE, Keller SR, Choi KM, Magnuson MA & Lawrence JC Jr 2008 Muscle-specific deletion of rictor impairs insulin-stimulated glucose transport and enhances basal glycogen synthase activity. Molecular and Cellular Biology 28 61-70.
-
(2008)
Molecular and Cellular Biology
, vol.28
, pp. 61-70
-
-
Kumar, A.1
Harris, T.E.2
Keller, S.R.3
Choi, K.M.4
Magnuson, M.A.5
Lawrence Jr., J.C.6
-
27
-
-
33644869305
-
Chronic rosiglitazone treatment restores AMPKα2 activity in insulin-resistant rat skeletal muscle
-
Lessard SJ, Chen Z-P, Watt MJ, Hashem M, Reid JJ, Febbraio MA, Kemp BE & Hawley JA 2006 Chronic rosiglitazone treatment restores AMPKα2 activity in insulin-resistant rat skeletal muscle. American Journal of Physiology. Endocrinology and Metabolism 290 E251-E257.
-
(2006)
American Journal of Physiology. Endocrinology and Metabolism 290
-
-
Lessard, S.J.1
Chen, Z.-P.2
Watt, M.J.3
Hashem, M.4
Reid, J.J.5
Febbraio, M.A.6
Kemp, B.E.7
Hawley, J.A.8
-
28
-
-
34347390598
-
Tissue-specific effects of rosiglitazone and exercise in the treatment of lipid-induced insulin resistance
-
DOI 10.2337/db06-1065
-
Lessard SJ, Rivas DA, Chen Z-P, Bonen A, Febbraio MA, Reeder DW, Kemp BE, Yaspelkis BB III & Hawley JA 2007 Tissue-specific effects of rosiglitazone and exercise in the treatment of lipid-induced insulin resistance. Diabetes 56 1856-1864. (Pubitemid 47025459)
-
(2007)
Diabetes
, vol.56
, Issue.7
, pp. 1856-1864
-
-
Lessard, S.J.1
Rivas, D.A.2
Chen, Z.-P.3
Bonen, A.4
Febbraio, M.A.5
Reeder, D.W.6
Kemp, B.E.7
Yaspelkis III, B.B.8
Hawley, J.A.9
-
29
-
-
33750684953
-
Role of insulin, adipocyte hormones, and nutrient-sensing pathways in regulating fuel metabolism and energy homeostasis: A nutritional perspective of diabetes, obesity, and cancer
-
Marshall S 2006 Role of insulin, adipocyte hormones, and nutrient-sensing pathways in regulating fuel metabolism and energy homeostasis: a nutritional perspective of diabetes, obesity, and cancer. Science's STKE 2006 re7.
-
(2006)
Science's STKE
, vol.2006
-
-
Marshall, S.1
-
30
-
-
34547683916
-
Changes in signalling pathways regulating protein synthesis in human muscle in the recovery period after endurance exercise
-
Mascher H, Andersson H, Nilsson P-A, Ekblom B & Blomstrand E 2007 Changes in signalling pathways regulating protein synthesis in human muscle in the recovery period after endurance exercise. Acta Physiologica 191 67-75.
-
(2007)
Acta Physiologica
, vol.191
, pp. 67-75
-
-
Mascher, H.1
Andersson, H.2
Nilsson, P.-A.3
Ekblom, B.4
Blomstrand, E.5
-
31
-
-
57349116906
-
Rapamycin does not improve insulin sensitivity despite elevated mammalian target of rapamycin complex 1 activity in muscles of ob/ob mice
-
Miller AM, Brestoff JR, Phelps CB, Berk EZ & Reynolds TH IV 2008 Rapamycin does not improve insulin sensitivity despite elevated mammalian target of rapamycin complex 1 activity in muscles of ob/ob mice. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology 295 R1431-R1438.
-
(2008)
American Journal of Physiology. Regulatory, Integrative and Comparative Physiology
, vol.295
-
-
Miller, A.M.1
Brestoff, J.R.2
Phelps, C.B.3
Berk, E.Z.4
Reynolds IV, T.H.5
-
32
-
-
38649124952
-
Effects of contraction and insulin on protein synthesis, AMP-activated protein kinase and phosphorylation state of translation factors in rat skeletal muscle
-
Miranda L, Horman S, De Potter I, Hue L, Jensen J & Rider MH 2008 Effects of contraction and insulin on protein synthesis, AMP-activated protein kinase and phosphorylation state of translation factors in rat skeletal muscle. Pflügers Archiv 455 1129-1140.
-
(2008)
Pflügers Archiv
, vol.455
, pp. 1129-1140
-
-
Miranda, L.1
Horman, S.2
De Potter, I.3
Hue, L.4
Jensen, J.5
Rider, M.H.6
-
33
-
-
34548092167
-
Activation of mammalian target of rapamycin complex 1 and insulin resistance induced by palmitate in hepatocytes
-
DOI 10.1016/j.bbrc.2007.08.004, PII S0006291X07017068
-
Mordier S & Iynedjian PB 2007 Activation of mammalian target of rapamycin complex 1 and insulin resistance induced by palmitate in hepatocytes. Biochemical and Biophysical Research Communications 362 206-211. (Pubitemid 47296312)
-
(2007)
Biochemical and Biophysical Research Communications
, vol.362
, Issue.1
, pp. 206-211
-
-
Mordier, S.1
Iynedjian, P.B.2
-
34
-
-
5644285347
-
In rat hepatocytes glucagon increases mammalian target of rapamycin phosphorylation on serine 2448 but antagonizes the phosphorylation of its downstream targets induced by insulin and amino acids
-
Mothe-Satney I, Gautier N, Hinault C, Lawrence JC Jr & Van Obberghen E 2004 In rat hepatocytes glucagon increases mammalian target of rapamycin phosphorylation on serine 2448 but antagonizes the phosphorylation of its downstream targets induced by insulin and amino acids. Journal of Biological Chemistry 279 42628-42637.
-
(2004)
Journal of Biological Chemistry
, vol.279
, pp. 42628-42637
-
-
Mothe-Satney, I.1
Gautier, N.2
Hinault, C.3
Lawrence Jr., J.C.4
Van Obberghen, E.5
-
36
-
-
7044221791
-
Nutrient sensor links obesity with diabetes risk
-
DOI 10.1038/nm1004-1049
-
Patti ME & Kahn BB 2004 Nutrient sensor links obesity with diabetes risk. Nature Medicine 10 1049-1050. (Pubitemid 39424863)
-
(2004)
Nature Medicine
, vol.10
, Issue.10
, pp. 1049-1050
-
-
Patti, M.-E.1
Kahn, B.B.2
-
37
-
-
0001437616
-
Bidirectional modulation of insulin action by amino acids
-
Patti M-E, Brambilla E, Luzi L, Landaker EJ & Ronald Kahn C 1998 Bidirectional modulation of insulin action by amino acids. Journal of Clinical Investigation 101 1519-1529. (Pubitemid 28166850)
-
(1998)
Journal of Clinical Investigation
, vol.101
, Issue.7
, pp. 1519-1529
-
-
Patti, M.-E.1
Brambilla, E.2
Luzi, L.3
Landaker, E.J.4
Kahn, C.R.5
-
38
-
-
51449103367
-
Prolonged exposure to palmitate impairs fatty acid oxidation despite activation of AMP-activated protein kinase in skeletal muscle cells
-
Pimenta AS, Gaidhu MP, Habib S, So M, Fediuc S, Mirpourian M, Musheev M, Curi R & Ceddia RB 2008 Prolonged exposure to palmitate impairs fatty acid oxidation despite activation of AMP-activated protein kinase in skeletal muscle cells. Journal of Cellular Physiology 217 478-485.
-
(2008)
Journal of Cellular Physiology
, vol.217
, pp. 478-485
-
-
Pimenta, A.S.1
Gaidhu, M.P.2
Habib, S.3
So, M.4
Fediuc, S.5
Mirpourian, M.6
Musheev, M.7
Curi, R.8
Ceddia, R.B.9
-
39
-
-
3342895823
-
Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton
-
DOI 10.1016/j.cub.2004.06.054, PII S0960982204004713
-
Sarbassov DD, Ali SM, Kim D-H, Guertin DA, Latek RR, Erdjument-Bromage H, Tempst P & Sabatini DM 2004 Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton. Current Biology 14 1296-1302. (Pubitemid 38991819)
-
(2004)
Current Biology
, vol.14
, Issue.14
, pp. 1296-1302
-
-
Dos D, S.1
Ali, S.M.2
Kim, D.-H.3
Guertin, D.A.4
Latek, R.R.5
Erdjument-Bromage, H.6
Tempst, P.7
Sabatini, D.M.8
-
40
-
-
13844312400
-
Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex
-
Sarbassov DD, Guertin DA, Ali SM & Sabatini DM 2005 Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex. Science 307 1098-1101.
-
(2005)
Science
, vol.307
, pp. 1098-1101
-
-
Sarbassov, D.D.1
Guertin, D.A.2
Ali, S.M.3
Sabatini, D.M.4
-
41
-
-
33646023695
-
Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB
-
Sarbassov DD, Ali SM, Sengupta S, Sheen J-H, Hsu PP, Bagley AF, Markhard AL & Sabatini DM 2006 Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB. Molecular Cell 22 159-168.
-
(2006)
Molecular Cell
, vol.22
, pp. 159-168
-
-
Sarbassov, D.D.1
Ali, S.M.2
Sengupta, S.3
Sheen, J.-H.4
Hsu, P.P.5
Bagley, A.F.6
Markhard, A.L.7
Sabatini, D.M.8
-
42
-
-
33748752151
-
The mammalian target of rapamycin (mTOR) pathway regulates mitochondrial oxygen consumption and oxidative capacity
-
DOI 10.1074/jbc.M603536200
-
Schieke SM, Phillips D, McCoy JP Jr, Aponte AM, Shen R-F, Balaban RS & Finkel T 2006 The mammalian target of rapamycin (mTOR) pathway regulates mitochondrial oxygen consumption and oxidative capacity. Journal of Biological Chemistry 281 27643-27652. (Pubitemid 44401789)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.37
, pp. 27643-27652
-
-
Schieke, S.M.1
Phillips, D.2
McCoy Jr., J.P.3
Aponte, A.M.4
Shen, R.-F.5
Balaban, R.S.6
Finkel, T.7
-
43
-
-
35248820393
-
Rapamycin-mediated inhibition of mammalian target of rapamycin in skeletal muscle cells reduces glucose utilization and increases fatty acid oxidation
-
DOI 10.1016/j.metabol.2006.08.002, PII S0026049506002824
-
Sipula IJ, Brown NF & Perdomo G 2006 Rapamycin-mediated inhibition of mammalian target of rapamycin in skeletal muscle cells reduces glucose utilization and increases fatty acid oxidation. Metabolism 55 1637-1644. (Pubitemid 44827130)
-
(2006)
Metabolism: Clinical and Experimental
, vol.55
, Issue.12
, pp. 1637-1644
-
-
Sipula, I.J.1
Brown, N.F.2
Perdomo, G.3
-
44
-
-
33244464562
-
Critical nodes in signalling pathways: Insights into insulin action
-
DOI 10.1038/nrm1837, PII NRM1837
-
Taniguchi CM, Emanuelli B & Kahn CR 2006 Critical nodes in signalling pathways: insights into insulin action. Nature Reviews. Molecular Cell Biology 7 85-96. (Pubitemid 43278292)
-
(2006)
Nature Reviews Molecular Cell Biology
, vol.7
, Issue.2
, pp. 85-96
-
-
Taniguchi, C.M.1
Emanuelli, B.2
Kahn, C.R.3
-
45
-
-
0035851205
-
Amino acid and insulin signaling via the mTOR/p70 S6 kinase pathway. a negative feedback mechanism leading to insulin resistance in skeletal muscle cells
-
Tremblay F & Marette A 2001 Amino acid and insulin signaling via the mTOR/p70 S6 kinase pathway. A negative feedback mechanism leading to insulin resistance in skeletal muscle cells. Journal of Biological Chemistry 276 38052-38060. (Pubitemid 37384057)
-
(2001)
Journal of Biological Chemistry
, vol.276
, Issue.41
, pp. 38052-38060
-
-
Tremblay, F.1
Marette, A.2
-
46
-
-
35348832340
-
Identification of IRS-1 Ser-1101 as a target of S6K1 in nutrient- and obesity-induced insulin resistance
-
Tremblay F, Brûlé S, Um SH, Li Y, Masuda K, Roden M, Sun XJ, Krebs M, Polakiewicz RD, George Tet al. 2007 Identification of IRS-1 Ser-1101 as a target of S6K1 in nutrient- and obesity-induced insulin resistance. PNAS 104 14056-14061.
-
(2007)
PNAS
, vol.104
, pp. 14056-14061
-
-
Tremblay, F.1
Brûlé, S.2
Um, S.H.3
Li, Y.4
Masuda, K.5
Roden, M.6
Sun, X.J.7
Krebs, M.8
Polakiewicz, R.D.9
George, T.10
-
47
-
-
4544220704
-
Absence of S6K1 protects against age- And diet-induced obesity while enhancing insulin sensitivity
-
DOI 10.1038/nature02866
-
Um SH, Frigerio F, Watanabe M, Picard F, Joaquin M, Sticker M, Fumagalli S, Allegrini PR, Kozma SC, Auwerx J et al. 2004 Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity. Nature 431 200-205. (Pubitemid 39243474)
-
(2004)
Nature
, vol.431
, Issue.7005
, pp. 200-205
-
-
Um, S.H.1
Frigerio, F.2
Watanabe, M.3
Picard, F.4
Joaquin, M.5
Sticker, M.6
Fumagalli, S.7
Allegrini, P.R.8
Kozma, S.C.9
Auwerx, J.10
Thomas, G.11
-
48
-
-
33744505375
-
Nutrient overload, insulin resistance, and ribosomal protein S6 kinase 1, S6K1
-
DOI 10.1016/j.cmet.2006.05.003, PII S1550413106001586
-
Um SH, D'Alessio D & Thomas G 2006 Nutrient overload, insulin resistance, and ribosomal protein S6 kinase 1, S6K1. Cell Metabolism 3 393-402. (Pubitemid 43811780)
-
(2006)
Cell Metabolism
, vol.3
, Issue.6
, pp. 393-402
-
-
Um, S.H.1
D'Alessio, D.2
Thomas, G.3
-
49
-
-
33745024082
-
Exercise-induced alterations in extracellular signal-regulated kinase 1/ 2 and mammalian target of rapamycin (mTOR) signalling to regulatory mechanisms of mRNA translation in mouse muscle
-
DOI 10.1113/jphysiol.2005.103481
-
Williamson DL, Kubica N, Kimball SR & Jefferson LS 2006 Exercise-induced alterations in extracellular signal-regulated kinase 1/2 and mammalian target of rapamycin (mTOR) signalling to regulatory mechanisms of mRNA translation in mouse muscle. Journal of Physiology 573 497-510. (Pubitemid 43871062)
-
(2006)
Journal of Physiology
, vol.573
, Issue.2
, pp. 497-510
-
-
Williamson, D.L.1
Kubica, N.2
Kimball, S.R.3
Jefferson, L.S.4
-
50
-
-
34247171304
-
Selective control of skeletal muscle differentiation by Akt1
-
DOI 10.1074/jbc.C600315200
-
Wilson EM & Rotwein P 2007 Selective control of skeletal muscle differentiation by Akt1. Journal of Biological Chemistry 282 5106-5110. (Pubitemid 47093711)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.8
, pp. 5106-5110
-
-
Wilson, E.M.1
Rotwein, P.2
-
51
-
-
7144253117
-
Lactic acid efflux from white skeletal muscle is catalyzed by the monocarboxylate transporter isoform MCT3
-
DOI 10.1074/jbc.273.26.15920
-
Wilson MC, Jackson VN, Heddle C, Price NT, Pilegaard H, Juel C, Bonen A, Montgomery I, Hutter OF & Halestrap AP 1998 Lactic acid efflux from white skeletal muscle Is catalyzed by the monocarboxylate transporter isoform MCT3. Journal of Biological Chemistry 273 15920-15926. (Pubitemid 28311355)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.26
, pp. 15920-15926
-
-
Wilson, M.C.1
Jackson, V.N.2
Heddle, C.3
Price, N.T.4
Pilegaard, H.5
Juel, C.6
Bonen, A.7
Montgomery, I.8
Hutter, O.F.9
Halestrap, A.P.10
-
52
-
-
23944444300
-
Health consequences of obesity in the elderly: A review of four unresolved questions
-
DOI 10.1038/sj.ijo.0803005
-
Zamboni M, Mazzali G, Zoico E, Harris TB, Meigs JB, Di Francesco V, Fantin F, Bissoli L & Bosello O 2005 Health consequences of obesity in the elderly: a review of four unresolved questions. International Journal of Obesity 29 1011-1029. (Pubitemid 41192208)
-
(2005)
International Journal of Obesity
, vol.29
, Issue.9
, pp. 1011-1029
-
-
Zamboni, M.1
Mazzali, G.2
Zoico, E.3
Harris, T.B.4
Meigs, J.B.5
Di Francesco, V.6
Fantin, F.7
Bissoli, L.8
Bosello, O.9
|