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Volumn 26, Issue 14, 2006, Pages 5336-5347

5′-AMP-activated protein kinase (AMPK) is induced by low-oxygen and glucose deprivation conditions found in solid-tumor microenvironments

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; GLUCOSE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; OXYGEN; PIMONIDAZOLE; STRESS ACTIVATED PROTEIN KINASE; 5' AMP ACTIVATED PROTEIN KINASE; 5'-AMP-ACTIVATED PROTEIN KINASE; ACETYL COENZYME A CARBOXYLASE; HIF1A PROTEIN, MOUSE; MULTIENZYME COMPLEX; PROTEIN SERINE THREONINE KINASE;

EID: 33745840203     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.00166-06     Document Type: Article
Times cited : (376)

References (61)
  • 2
    • 1342310736 scopus 로고    scopus 로고
    • Nitric oxide switches on glycolysis through the AMP protein kinase and 6-phosphofructo-2-kinase pathway
    • Almeida, A., S. Moncada, and J. P. Bolanos. 2004. Nitric oxide switches on glycolysis through the AMP protein kinase and 6-phosphofructo-2-kinase pathway. Nat. Cell Biol. 6:45-51.
    • (2004) Nat. Cell Biol. , vol.6 , pp. 45-51
    • Almeida, A.1    Moncada, S.2    Bolanos, J.P.3
  • 3
    • 11344251540 scopus 로고    scopus 로고
    • Erythropoietin and erythropoietin receptor expression in head and neck cancer: Relationship to tumor hypoxia
    • Arcasoy, M. O., K. Amin, S. C. Chou, Z. A. Haroon, M. Varia, and J. A. Raleigh. 2005. Erythropoietin and erythropoietin receptor expression in head and neck cancer: relationship to tumor hypoxia. Clin. Cancer Res. 11:20-27.
    • (2005) Clin. Cancer Res. , vol.11 , pp. 20-27
    • Arcasoy, M.O.1    Amin, K.2    Chou, S.C.3    Haroon, Z.A.4    Varia, M.5    Raleigh, J.A.6
  • 4
    • 0742305866 scopus 로고    scopus 로고
    • Network biology: Understanding the cell's functional organization
    • Barabasi, A. L., and Z. N. Oltvai. 2004. Network biology: understanding the cell's functional organization. Nat. Rev. Genet. 5:101-113.
    • (2004) Nat. Rev. Genet. , vol.5 , pp. 101-113
    • Barabasi, A.L.1    Oltvai, Z.N.2
  • 5
    • 0035929337 scopus 로고    scopus 로고
    • Insulin antagonizes AMP-activated protein kinase activation by ischemia or anoxia in rat hearts, without affecting total adenine nucleotides
    • Beauloye, C., A. S. Marsin, L. Bertrand, U. Krause, D. G. Hardie, J. L. Vanoverschelde, and L. Hue. 2001. Insulin antagonizes AMP-activated protein kinase activation by ischemia or anoxia in rat hearts, without affecting total adenine nucleotides. FEBS Lett. 505:348-352.
    • (2001) FEBS Lett. , vol.505 , pp. 348-352
    • Beauloye, C.1    Marsin, A.S.2    Bertrand, L.3    Krause, U.4    Hardie, D.G.5    Vanoverschelde, J.L.6    Hue, L.7
  • 6
    • 23044514282 scopus 로고    scopus 로고
    • Activating AMP-activated protein kinase without AMP
    • Birnbaum, M. J. 2005. Activating AMP-activated protein kinase without AMP. Mol. Cell 19:289-290.
    • (2005) Mol. Cell , vol.19 , pp. 289-290
    • Birnbaum, M.J.1
  • 7
    • 3142587052 scopus 로고    scopus 로고
    • Dysregulation of HIF and VEGF is a unifying feature of the familial hamartoma syndromes
    • Brugarolas, J., and W. G. Kaelin, Jr. 2004. Dysregulation of HIF and VEGF is a unifying feature of the familial hamartoma syndromes. Cancer Cell 6:7-10.
    • (2004) Cancer Cell , vol.6 , pp. 7-10
    • Brugarolas, J.1    Kaelin Jr., W.G.2
  • 8
    • 4344571862 scopus 로고    scopus 로고
    • Tumor-dependent kinetics of partial pressure of oxygen fluctuations during air and oxygen breathing
    • Cardenas-Navia, L. I., D. Yu, R. D. Braun, D. M. Brizel, T. W. Secomb, and M. W. Dewhirst. 2004. Tumor-dependent kinetics of partial pressure of oxygen fluctuations during air and oxygen breathing. Cancer Res. 64:6010-6017.
    • (2004) Cancer Res. , vol.64 , pp. 6010-6017
    • Cardenas-Navia, L.I.1    Yu, D.2    Braun, R.D.3    Brizel, D.M.4    Secomb, T.W.5    Dewhirst, M.W.6
  • 9
    • 0347318052 scopus 로고    scopus 로고
    • The AMP-activated protein kinase cascade - A unifying system for energy control
    • Carling, D. 2004. The AMP-activated protein kinase cascade-a unifying system for energy control. Trends Biochem. Sci. 29:18-24.
    • (2004) Trends Biochem. Sci. , vol.29 , pp. 18-24
    • Carling, D.1
  • 10
    • 1542269248 scopus 로고    scopus 로고
    • Evidence that involucrin, a marker for differentiation, is oxygen regulated in human squamous cell carcinomas
    • Chou, S. C., Y. Azuma, M. A. Varia, and J. A. Raleigh. 2004. Evidence that involucrin, a marker for differentiation, is oxygen regulated in human squamous cell carcinomas. Br. J. Cancer 90:728-735.
    • (2004) Br. J. Cancer , vol.90 , pp. 728-735
    • Chou, S.C.1    Azuma, Y.2    Varia, M.A.3    Raleigh, J.A.4
  • 11
    • 0037031895 scopus 로고    scopus 로고
    • Hypoxia and nitric oxide treatment confer tolerance to glucose starvation in a 5′-AMP-activated protein kinase-dependent manner
    • Esumi, H., K. Izuishi, K. Kato, K. Hashimoto, Y. Kurashima, A. Kishimoto, T. Ogura, and T. Ozawa. 2002. Hypoxia and nitric oxide treatment confer tolerance to glucose starvation in a 5′-AMP-activated protein kinase-dependent manner. J. Biol. Chem. 277:32791-32798.
    • (2002) J. Biol. Chem. , vol.277 , pp. 32791-32798
    • Esumi, H.1    Izuishi, K.2    Kato, K.3    Hashimoto, K.4    Kurashima, Y.5    Kishimoto, A.6    Ogura, T.7    Ozawa, T.8
  • 13
    • 18044388214 scopus 로고    scopus 로고
    • Hypoxia and AMP independently regulate AMP-activated protein kinase activity in the heart
    • Frederich, M., L. Zhang, and J. A. Balschi. 2005. Hypoxia and AMP independently regulate AMP-activated protein kinase activity in the heart. Am. J. Physiol. Heart Circ. Physiol. 288:2412-2421.
    • (2005) Am. J. Physiol. Heart Circ. Physiol. , vol.288 , pp. 2412-2421
    • Frederich, M.1    Zhang, L.2    Balschi, J.A.3
  • 14
    • 0033119833 scopus 로고    scopus 로고
    • Tumor-derived expression of vascular endothelial growth factor is a critical factor in tumor expansion and vascular function
    • Grunstein, J., W. G. Roberts, O. Mathieu-Costello, D. Hanahan, and R. S. Johnson. 1999. Tumor-derived expression of vascular endothelial growth factor is a critical factor in tumor expansion and vascular function. Cancer Res. 59:1592-1598.
    • (1999) Cancer Res. , vol.59 , pp. 1592-1598
    • Grunstein, J.1    Roberts, W.G.2    Mathieu-Costello, O.3    Hanahan, D.4    Johnson, R.S.5
  • 15
    • 31544464931 scopus 로고    scopus 로고
    • Fibronectin stimulates non-small cell lung carcinoma cell growth through activation of Akt/mammalian target of rapamycin/S6 kinase and inactivation of LKB1/AMP-activated protein kinase signal pathways
    • Han, S., F. R. Khuri, and J. Roman. 2006. Fibronectin stimulates non-small cell lung carcinoma cell growth through activation of Akt/mammalian target of rapamycin/S6 kinase and inactivation of LKB1/AMP-activated protein kinase signal pathways. Cancer Res. 66:315-323.
    • (2006) Cancer Res. , vol.66 , pp. 315-323
    • Han, S.1    Khuri, F.R.2    Roman, J.3
  • 16
    • 33644978143 scopus 로고    scopus 로고
    • Rosiglitazone suppresses human lung carcinoma cell growth through PPAR-γ-dependent and PPAR-γ-independent signal pathways
    • Han, S., and J. Roman. 2006. Rosiglitazone suppresses human lung carcinoma cell growth through PPAR-γ-dependent and PPAR-γ- independent signal pathways. Mol. Cancer Ther. 5:430-437.
    • (2006) Mol. Cancer Ther. , vol.5 , pp. 430-437
    • Han, S.1    Roman, J.2
  • 17
    • 0018933483 scopus 로고
    • Characteristics of an SV40-plasmid recombinant and its movement into and out of the genome of a murine cell
    • Hanahan, D., D. Lane, L. Lipsich, M. Wigler, and M. Botchan. 1980. Characteristics of an SV40-plasmid recombinant and its movement into and out of the genome of a murine cell. Cell 21:127-139.
    • (1980) Cell , vol.21 , pp. 127-139
    • Hanahan, D.1    Lane, D.2    Lipsich, L.3    Wigler, M.4    Botchan, M.5
  • 18
    • 0036864358 scopus 로고    scopus 로고
    • Regulation of fatty acid synthesis and oxidation by the AMP-activated protein kinase
    • Hardie, D. G., and D. A. Pan. 2002. Regulation of fatty acid synthesis and oxidation by the AMP-activated protein kinase. Biochem. Soc. Trans. 30:1064-1070.
    • (2002) Biochem. Soc. Trans. , vol.30 , pp. 1064-1070
    • Hardie, D.G.1    Pan, D.A.2
  • 19
    • 0038199737 scopus 로고    scopus 로고
    • Management of cellular energy by the AMP-activated protein kinase system
    • Hardie, D. G., J. W. Scott, D. A. Pan, and E. R. Hudson. 2003. Management of cellular energy by the AMP-activated protein kinase system. FEBS Lett. 546:113-120.
    • (2003) FEBS Lett. , vol.546 , pp. 113-120
    • Hardie, D.G.1    Scott, J.W.2    Pan, D.A.3    Hudson, E.R.4
  • 20
    • 0142149149 scopus 로고    scopus 로고
    • Myocardial ischemia and increased heart work modulate the phosphorylation state of cukaryotic elongation factor-2
    • Horman, S., C. Beauloye, D. Vertommen, J. L. Vanoverschelde, L. Hue, and M. H. Rider. 2003. Myocardial ischemia and increased heart work modulate the phosphorylation state of cukaryotic elongation factor-2. J. Biol. Chem. 278:41970-41976.
    • (2003) J. Biol. Chem. , vol.278 , pp. 41970-41976
    • Horman, S.1    Beauloye, C.2    Vertommen, D.3    Vanoverschelde, J.L.4    Hue, L.5    Rider, M.H.6
  • 21
    • 0037490210 scopus 로고    scopus 로고
    • Hypoxia-inducible factor and its biomedical relevance
    • Huang, L. E., and H. F. Bunn. 2003. Hypoxia-inducible factor and its biomedical relevance. J. Biol. Chem. 278:19575-19578.
    • (2003) J. Biol. Chem. , vol.278 , pp. 19575-19578
    • Huang, L.E.1    Bunn, H.F.2
  • 25
    • 0029998491 scopus 로고    scopus 로고
    • Cellular transformation and malignancy induced by ras require c-jun
    • Johnson, R., B. Spiegelman, D. Hanahan, and R. Wisdom. 1996. Cellular transformation and malignancy induced by ras require c-jun. Mol. Cell. Biol. 16:4504-4511.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 4504-4511
    • Johnson, R.1    Spiegelman, B.2    Hanahan, D.3    Wisdom, R.4
  • 26
    • 0345832116 scopus 로고    scopus 로고
    • Knockout of the α2 but not α1 5′-AMP-activated protein kinase isoform abolishes 5-aminoimidazole-4-carboxamide-1-β4-ribofuranoside but not contraction-induced glucose uptake in skeletal muscle
    • Jorgensen, S. B., B. Viollet, F. Andreelli, C. Frosig, J. B. Birk, P. Schjerling, S. Vaulont, E. A. Richter, and J. F. Wojtaszewski. 2004. Knockout of the α2 but not α1 5′-AMP-activated protein kinase isoform abolishes 5-aminoimidazole-4-carboxamide-1-β4-ribofuranoside but not contraction-induced glucose uptake in skeletal muscle. J. Biol. Chem. 279:1070-1079.
    • (2004) J. Biol. Chem. , vol.279 , pp. 1070-1079
    • Jorgensen, S.B.1    Viollet, B.2    Andreelli, F.3    Frosig, C.4    Birk, J.B.5    Schjerling, P.6    Vaulont, S.7    Richter, E.A.8    Wojtaszewski, J.F.9
  • 27
    • 0037026608 scopus 로고    scopus 로고
    • Critical roles of AMP-activated protein kinase in constitutive tolerance of cancer cells to nutrient deprivation and tumor formation
    • Kato, K., T. Ogura, A. Kishimoto, Y. Minegishi, N. Nakajima, M. Miyazaki, and H. Esumi. 2002. Critical roles of AMP-activated protein kinase in constitutive tolerance of cancer cells to nutrient deprivation and tumor formation. Oncogene 21:6082-6090.
    • (2002) Oncogene , vol.21 , pp. 6082-6090
    • Kato, K.1    Ogura, T.2    Kishimoto, A.3    Minegishi, Y.4    Nakajima, N.5    Miyazaki, M.6    Esumi, H.7
  • 28
    • 21344442127 scopus 로고    scopus 로고
    • Hypoxia inhibits adipocyte differentiation in a HDAC-independent manner
    • Kim, K. H., M. J. Song, J. Chung, H. Park, and J. B. Kim. 2005. Hypoxia inhibits adipocyte differentiation in a HDAC-independent manner. Biochem. Biophys. Res. Commun. 333:1178-1184.
    • (2005) Biochem. Biophys. Res. Commun. , vol.333 , pp. 1178-1184
    • Kim, K.H.1    Song, M.J.2    Chung, J.3    Park, H.4    Kim, J.B.5
  • 30
    • 24344461359 scopus 로고    scopus 로고
    • The interaction between HIF-1 and AP-1 transcription factors in response to low oxygen
    • Laderoute, K. 2005. The interaction between HIF-1 and AP-1 transcription factors in response to low oxygen. Semin. Cell Dev. Biol. 16:502-513.
    • (2005) Semin. Cell Dev. Biol. , vol.16 , pp. 502-513
    • Laderoute, K.1
  • 32
    • 2942568513 scopus 로고    scopus 로고
    • Glucose utilization is essential for hypoxia-inducible factor 1α-dependent phosphorylation of c-Jun
    • Laderoute, K. R., J. M. Calaoagan, M. Knapp, and R. S. Johnson. 2004. Glucose utilization is essential for hypoxia-inducible factor 1α-dependent phosphorylation of c-Jun. Mol. Cell. Biol. 24:4128-4137.
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 4128-4137
    • Laderoute, K.R.1    Calaoagan, J.M.2    Knapp, M.3    Johnson, R.S.4
  • 33
    • 0141960109 scopus 로고    scopus 로고
    • AMP-activated protein kinase activity is critical for hypoxia-inducible factor-1 transcriptional activity and its target gene expression under hypoxic conditions in DU145 cells
    • Lee, M., J. T. Hwang, H. J. Lee, S. N. Jung, I. Kang, S. G. Chi, S. S. Kim, and J. Ha. 2003. AMP-activated protein kinase activity is critical for hypoxia-inducible factor-1 transcriptional activity and its target gene expression under hypoxic conditions in DU145 cells. J. Biol. Chem. 278:39653-39661.
    • (2003) J. Biol. Chem. , vol.278 , pp. 39653-39661
    • Lee, M.1    Hwang, J.T.2    Lee, H.J.3    Jung, S.N.4    Kang, I.5    Chi, S.G.6    Kim, S.S.7    Ha, J.8
  • 34
    • 0037329494 scopus 로고    scopus 로고
    • AMP-activated protein kinase regulates gene expression by direct phosphorylation of nuclear proteins
    • Leff, T. 2003. AMP-activated protein kinase regulates gene expression by direct phosphorylation of nuclear proteins. Biochem. Soc. Trans. 31:224-227.
    • (2003) Biochem. Soc. Trans. , vol.31 , pp. 224-227
    • Leff, T.1
  • 35
    • 3142622910 scopus 로고    scopus 로고
    • The hypoxic tumor microenvironment and gene expression
    • Leo, C., A. J. Giaccia, and N. C. Denko. 2004. The hypoxic tumor microenvironment and gene expression. Semin. Radiat. Oncol. 14:207-214.
    • (2004) Semin. Radiat. Oncol. , vol.14 , pp. 207-214
    • Leo, C.1    Giaccia, A.J.2    Denko, N.C.3
  • 37
    • 11244300732 scopus 로고    scopus 로고
    • LKB1, the multitasking tumour suppressor kinase
    • Marignani, P. A. 2005. LKB1, the multitasking tumour suppressor kinase. J. Clin. Pathol. 58:15-19.
    • (2005) J. Clin. Pathol. , vol.58 , pp. 15-19
    • Marignani, P.A.1
  • 38
    • 0037163076 scopus 로고    scopus 로고
    • The stimulation of glycolysis by hypoxia in activated monocytes is mediated by AMP-activated protein kinase and inducible 6-phosphofructo-2-kinase
    • Marsin, A., C. Bouzin, L. Bertrand, and L. Hue. 2002. The stimulation of glycolysis by hypoxia in activated monocytes is mediated by AMP-activated protein kinase and inducible 6-phosphofructo-2-kinase. J. Biol. Chem. 277:30778-30783.
    • (2002) J. Biol. Chem. , vol.277 , pp. 30778-30783
    • Marsin, A.1    Bouzin, C.2    Bertrand, L.3    Hue, L.4
  • 40
    • 26844514210 scopus 로고    scopus 로고
    • The metal responsive transcription factor 1 (MTF-1) contributes to HIF-1 activation during hypoxic stress
    • Murphy, B. J., B. Sato, T. P. Dalton, and K. R. Laderoute. 2005. The metal responsive transcription factor 1 (MTF-1) contributes to HIF-1 activation during hypoxic stress. Biochem. Biophys. Res. Commun. 337:860-867.
    • (2005) Biochem. Biophys. Res. Commun. , vol.337 , pp. 860-867
    • Murphy, B.J.1    Sato, B.2    Dalton, T.P.3    Laderoute, K.R.4
  • 41
    • 0042733154 scopus 로고    scopus 로고
    • AMP-activated protein kinase (AMPK) signaling in endothelial cells is essential for angiogenesis in response to hypoxic stress
    • Nagata, D., M. Mogi, and K. Walsh. 2003. AMP-activated protein kinase (AMPK) signaling in endothelial cells is essential for angiogenesis in response to hypoxic stress. J. Biol. Chem. 278:31000-31006.
    • (2003) J. Biol. Chem. , vol.278 , pp. 31000-31006
    • Nagata, D.1    Mogi, M.2    Walsh, K.3
  • 42
    • 33646247392 scopus 로고    scopus 로고
    • AMP-dependent protein kinase α2 isoform promotes hypoxia-induced VEGF expression in human glioblastoma
    • Neurath, K. M., M. P. Keough, T. Mikkelsen, and K. P. Claffey. 2006. AMP-dependent protein kinase α2 isoform promotes hypoxia-induced VEGF expression in human glioblastoma. Glia 53:733-743.
    • (2006) Glia , vol.53 , pp. 733-743
    • Neurath, K.M.1    Keough, M.P.2    Mikkelsen, T.3    Claffey, K.P.4
  • 43
    • 0842303171 scopus 로고    scopus 로고
    • HIF-1 and hypoxic response: The plot thickens
    • Poellinger, L., and R. S. Johnson. 2004. HIF-1 and hypoxic response: the plot thickens. Curr. Opin. Genet. Dev. 14:81-85.
    • (2004) Curr. Opin. Genet. Dev. , vol.14 , pp. 81-85
    • Poellinger, L.1    Johnson, R.S.2
  • 46
    • 28244466264 scopus 로고    scopus 로고
    • 5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside inhibits cancer cell proliferation in vitro and in vivo via AMP-activated protein kinase
    • Rattan, R., S. Giri, A. K. Singh, and I. Singh. 2005. 5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside inhibits cancer cell proliferation in vitro and in vivo via AMP-activated protein kinase. J. Biol. Chem. 280:39582-39593.
    • (2005) J. Biol. Chem. , vol.280 , pp. 39582-39593
    • Rattan, R.1    Giri, S.2    Singh, A.K.3    Singh, I.4
  • 47
    • 0141905919 scopus 로고    scopus 로고
    • Roles of 5′-AMP-activated protein kinase (AMPK) in mammalian glucose homoeostasis
    • Rutter, G. A., G. Da Silva Xavier, and I. Leclerc. 2003. Roles of 5′-AMP-activated protein kinase (AMPK) in mammalian glucose homoeostasis. Biochem. J. 375:1-16.
    • (2003) Biochem. J. , vol.375 , pp. 1-16
    • Rutter, G.A.1    Da Silva Xavier, G.2    Leclerc, I.3
  • 49
    • 20444490000 scopus 로고    scopus 로고
    • Spatial heterogeneity and oxygen dependence of glucose consumption in R3230Ac and fibrosarcomas of the Fischer 344 rat
    • Schroeder, T., H. Yuan, B. L. Viglianti, C. Peltz, S. Asopa, Z. Vujaskovic, and M. W. Dewhirst. 2005. Spatial heterogeneity and oxygen dependence of glucose consumption in R3230Ac and fibrosarcomas of the Fischer 344 rat. Cancer Res. 65:5163-5171.
    • (2005) Cancer Res. , vol.65 , pp. 5163-5171
    • Schroeder, T.1    Yuan, H.2    Viglianti, B.L.3    Peltz, C.4    Asopa, S.5    Vujaskovic, Z.6    Dewhirst, M.W.7
  • 50
    • 0142166332 scopus 로고    scopus 로고
    • Targeting HIF-1 for cancer therapy
    • Semenza, G. L. 2003. Targeting HIF-1 for cancer therapy. Nat. Rev. Cancer 3:721-732.
    • (2003) Nat. Rev. Cancer , vol.3 , pp. 721-732
    • Semenza, G.L.1
  • 51
    • 0034892665 scopus 로고    scopus 로고
    • The novel tubulin-binding drug BTO-956 inhibits R3230ac mammary carcinoma growth and angiogenesis in Fischer 344 rats
    • Shan, S., A. C. Lockhart, W. Y. Saito, A. M. Knapp, K. R. Laderoute, and M. W. Dewhirst. 2001. The novel tubulin-binding drug BTO-956 inhibits R3230ac mammary carcinoma growth and angiogenesis in Fischer 344 rats. Clin. Cancer Res. 7:2590-2596.
    • (2001) Clin. Cancer Res. , vol.7 , pp. 2590-2596
    • Shan, S.1    Lockhart, A.C.2    Saito, W.Y.3    Knapp, A.M.4    Laderoute, K.R.5    Dewhirst, M.W.6
  • 52
    • 1542618348 scopus 로고    scopus 로고
    • The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress
    • Shaw, R. J., M. Kosmatka, N. Bardeesy, R. L. Hurley, L. A. Witters, R. A. DePinho, and L. C. Cantley. 2004. The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress. Proc. Natl. Acad. Sci. USA 101:3329-3335.
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 3329-3335
    • Shaw, R.J.1    Kosmatka, M.2    Bardeesy, N.3    Hurley, R.L.4    Witters, L.A.5    Depinho, R.A.6    Cantley, L.C.7
  • 53
    • 0037414761 scopus 로고    scopus 로고
    • Identification of a novel protein kinase mediating Akt survival signaling to the ATM protein
    • Suzuki, A., G. Kusakai, A. Kishimoto, J. Lu, T. Ogura, M. F. Lavin, and H. Esumi. 2003. Identification of a novel protein kinase mediating Akt survival signaling to the ATM protein. J. Biol. Chem. 278:48-53.
    • (2003) J. Biol. Chem. , vol.278 , pp. 48-53
    • Suzuki, A.1    Kusakai, G.2    Kishimoto, A.3    Lu, J.4    Ogura, T.5    Lavin, M.F.6    Esumi, H.7
  • 54
    • 0142027180 scopus 로고    scopus 로고
    • Induction of cell-cell detachment during glucose starvation through F-actin conversion by SNARK, the fourth member of the AMP-activated protein kinase catalytic subunit family
    • Suzuki, A., G. Kusakai, A. Kishimoto, Y. Minegichi, T. Ogura, and H. Esumi. 2003. Induction of cell-cell detachment during glucose starvation through F-actin conversion by SNARK, the fourth member of the AMP-activated protein kinase catalytic subunit family. Biochem. Biophys. Res. Commun. 311:156-161.
    • (2003) Biochem. Biophys. Res. Commun. , vol.311 , pp. 156-161
    • Suzuki, A.1    Kusakai, G.2    Kishimoto, A.3    Minegichi, Y.4    Ogura, T.5    Esumi, H.6
  • 56
  • 57
    • 1842505299 scopus 로고    scopus 로고
    • ARK5 is a tumor invasion-associated factor downstream of Akt signaling
    • Suzuki, A., J. Lu, G. Kusakai, A. Kishimoto, T. Ogura, and H. Esumi. 2004. ARK5 is a tumor invasion-associated factor downstream of Akt signaling. Mol. Cell. Biol. 24:3526-3535.
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 3526-3535
    • Suzuki, A.1    Lu, J.2    Kusakai, G.3    Kishimoto, A.4    Ogura, T.5    Esumi, H.6
  • 58
    • 27144489669 scopus 로고    scopus 로고
    • AMP-activated protein kinase protects cardiomyocytes against hypoxic injury through attenuation of endoplasmic reticulum stress
    • Terai, K., Y. Hiramoto, M. Masaki, S. Sugiyama, T. Kuroda, M. Hori, I. Kawase, and H. Hirota. 2005. AMP-activated protein kinase protects cardiomyocytes against hypoxic injury through attenuation of endoplasmic reticulum stress. Mol. Cell. Biol. 25:9554-9575.
    • (2005) Mol. Cell. Biol. , vol.25 , pp. 9554-9575
    • Terai, K.1    Hiramoto, Y.2    Masaki, M.3    Sugiyama, S.4    Kuroda, T.5    Hori, M.6    Kawase, I.7    Hirota, H.8
  • 59
    • 3142587028 scopus 로고    scopus 로고
    • Tumor microenvironmental physiology and its implications for radiation oncology
    • Vaupel, P. 2004. Tumor microenvironmental physiology and its implications for radiation oncology. Semin. Radiat. Oncol. 14:198-206.
    • (2004) Semin. Radiat. Oncol. , vol.14 , pp. 198-206
    • Vaupel, P.1
  • 61
    • 15444362131 scopus 로고    scopus 로고
    • Glucose deprivation increases mRNA stability of vascular endothelial growth factor through activation of AMP-activated protein kinase in DU145 prostate carcinoma
    • Yun, H., M. Lee, S. S. Kim, and J. Ha. 2005. Glucose deprivation increases mRNA stability of vascular endothelial growth factor through activation of AMP-activated protein kinase in DU145 prostate carcinoma. J. Biol. Chem. 280:9963-9972.
    • (2005) J. Biol. Chem. , vol.280 , pp. 9963-9972
    • Yun, H.1    Lee, M.2    Kim, S.S.3    Ha, J.4


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