메뉴 건너뛰기




Volumn 87, Issue 4, 2013, Pages 611-632

Mechanisms of RAS/β-catenin interactions

Author keywords

Catenin; Crosstalk; ERK; MAPK signaling; Oncogene; WNT signaling

Indexed keywords

BETA CATENIN; EPIDERMAL GROWTH FACTOR RECEPTOR; GLYCOGEN SYNTHASE KINASE 3BETA; K RAS PROTEIN; RAC1 PROTEIN; RAS PROTEIN; SCATTER FACTOR RECEPTOR; TRANSCRIPTION FACTOR; TRANSFORMING GROWTH FACTOR ALPHA; WNT PROTEIN;

EID: 84876680217     PISSN: 03405761     EISSN: 14320738     Source Type: Journal    
DOI: 10.1007/s00204-013-1035-3     Document Type: Review
Times cited : (33)

References (230)
  • 1
    • 33645859023 scopus 로고    scopus 로고
    • Mutations of beta-catenin and KRAS in colorectal carcinomas
    • 16614976 1:CAS:528:DC%2BD28XjsFyjt7s%3D 10.1007/s10620-006-3179-y
    • Abdel-Rahman WM (2006) Mutations of beta-catenin and KRAS in colorectal carcinomas. Dig Dis Sci 51(3):616-617
    • (2006) Dig Dis Sci , vol.51 , Issue.3 , pp. 616-617
    • Abdel-Rahman, W.M.1
  • 2
    • 77954036677 scopus 로고    scopus 로고
    • Activation of Wnt/beta-catenin signaling increases insulin sensitivity through a reciprocal regulation of Wnt10b and SREBP-1c in skeletal muscle cells
    • 20041157 10.1371/journal.pone.0008509 1:CAS:528:DC%2BC3cXhtlOmuw%3D%3D
    • Abiola M, Favier M, Christodoulou-Vafeiadou E, Pichard AL, Martelly I, Guillet-Deniau I (2009) Activation of Wnt/beta-catenin signaling increases insulin sensitivity through a reciprocal regulation of Wnt10b and SREBP-1c in skeletal muscle cells. PLoS ONE 4(12):e8509
    • (2009) PLoS ONE , vol.4 , Issue.12 , pp. 8509
    • Abiola, M.1    Favier, M.2    Christodoulou-Vafeiadou, E.3    Pichard, A.L.4    Martelly, I.5    Guillet-Deniau, I.6
  • 3
    • 84866934163 scopus 로고    scopus 로고
    • FoxM1 is vital in the Wnt/beta-catenin signaling pathogenesis of gliomas
    • 22430325 10.1016/j.wneu.2012.03.001
    • Abla AA, Turner JD, Sanai N (2012) FoxM1 is vital in the Wnt/beta-catenin signaling pathogenesis of gliomas. World Neurosurg 77(5-6):594-596
    • (2012) World Neurosurg , vol.77 , Issue.5-6 , pp. 594-596
    • Abla, A.A.1    Turner, J.D.2    Sanai, N.3
  • 4
    • 79959645720 scopus 로고    scopus 로고
    • Ras mutation cooperates with beta-catenin activation to drive bladder tumourigenesis
    • 21368895 1:CAS:528:DC%2BC3MXktFeisrY%3D 10.1038/cddis.2011.7
    • Ahmad I, Patel R, Liu Y, Singh LB, Taketo MM, Wu XR, Leung HY, Sansom OJ (2011) Ras mutation cooperates with beta-catenin activation to drive bladder tumourigenesis. Cell Death Dis 2:e124
    • (2011) Cell Death Dis , vol.2 , pp. 124
    • Ahmad, I.1    Patel, R.2    Liu, Y.3    Singh, L.B.4    Taketo, M.M.5    Wu, X.R.6    Leung, H.Y.7    Sansom, O.J.8
  • 5
    • 29244446792 scopus 로고    scopus 로고
    • Wnt proteins prevent apoptosis of both uncommitted osteoblast progenitors and differentiated osteoblasts by beta-catenin-dependent and -independent signaling cascades involving Src/ERK and phosphatidylinositol 3-kinase/AKT
    • 16251184 1:CAS:528:DC%2BD2MXhtlShsb3J 10.1074/jbc.M502168200
    • Almeida M, Han L, Bellido T, Manolagas SC, Kousteni S (2005) Wnt proteins prevent apoptosis of both uncommitted osteoblast progenitors and differentiated osteoblasts by beta-catenin-dependent and -independent signaling cascades involving Src/ERK and phosphatidylinositol 3-kinase/AKT. J Biol Chem 280(50):41342-41351
    • (2005) J Biol Chem , vol.280 , Issue.50 , pp. 41342-41351
    • Almeida, M.1    Han, L.2    Bellido, T.3    Manolagas, S.C.4    Kousteni, S.5
  • 6
    • 33847143644 scopus 로고    scopus 로고
    • Prolactin expression is induced in Jurkat T-cells by beta-catenin LEF-1, AP-1 and cAMP
    • 17240357 1:CAS:528:DC%2BD2sXhtlOgtbw%3D 10.1016/j.bbrc.2007.01.023
    • Andria ML, Reem GH (2007) Prolactin expression is induced in Jurkat T-cells by beta-catenin LEF-1, AP-1 and cAMP. Biochem Biophys Res Commun 354(2):598-602
    • (2007) Biochem Biophys Res Commun , vol.354 , Issue.2 , pp. 598-602
    • Andria, M.L.1    Reem, G.H.2
  • 7
    • 0035936026 scopus 로고    scopus 로고
    • Selective pressure during tumor promotion by phenobarbital leads to clonal outgrowth of beta-catenin-mutated mouse liver tumors
    • 11753661 1:CAS:528:DC%2BD3MXptFOntLY%3D 10.1038/sj.onc.1204982
    • Aydinlik H, Nguyen TD, Moennikes O, Buchmann A, Schwarz M (2001) Selective pressure during tumor promotion by phenobarbital leads to clonal outgrowth of beta-catenin-mutated mouse liver tumors. Oncogene 20(53):7812-7816
    • (2001) Oncogene , vol.20 , Issue.53 , pp. 7812-7816
    • Aydinlik, H.1    Nguyen, T.D.2    Moennikes, O.3    Buchmann, A.4    Schwarz, M.5
  • 8
    • 0032575093 scopus 로고    scopus 로고
    • Characterization of Wnt-1 and Wnt-2 induced growth alterations and signaling pathways in NIH3T3 fibroblasts
    • 9652750 1:CAS:528:DyaK1cXjvV2qsb8%3D 10.1038/sj.onc.1201797
    • Bafico A, Gazit A, Wu-Morgan SS, Yaniv A, Aaronson SA (1998) Characterization of Wnt-1 and Wnt-2 induced growth alterations and signaling pathways in NIH3T3 fibroblasts. Oncogene 16(21):2819-2825
    • (1998) Oncogene , vol.16 , Issue.21 , pp. 2819-2825
    • Bafico, A.1    Gazit, A.2    Wu-Morgan, S.S.3    Yaniv, A.4    Aaronson, S.A.5
  • 9
    • 1642454578 scopus 로고    scopus 로고
    • Transcriptional regulation of CYP2B1 induction in primary rat hepatocyte cultures: Repression by epidermal growth factor is mediated via a distal enhancer region
    • 14722249 1:CAS:528:DC%2BD2cXivVChs78%3D 10.1124/mol.65.1.172
    • Bauer D, Wolfram N, Kahl GF, Hirsch-Ernst KI (2004) Transcriptional regulation of CYP2B1 induction in primary rat hepatocyte cultures: repression by epidermal growth factor is mediated via a distal enhancer region. Mol Pharmacol 65(1):172-180
    • (2004) Mol Pharmacol , vol.65 , Issue.1 , pp. 172-180
    • Bauer, D.1    Wolfram, N.2    Kahl, G.F.3    Hirsch-Ernst, K.I.4
  • 10
    • 77949424255 scopus 로고    scopus 로고
    • Phenotype-assisted transcriptome analysis identifies FOXM1 downstream from Ras-MKK3-p38 to regulate in vitro cellular invasion
    • 20023695 1:CAS:528:DC%2BD1MXhsFyhsLjM 10.1038/onc.2009.436
    • Behren A, Muhlen S, Acuna Sanhueza GA, Schwager C, Plinkert PK, Huber PE, Abdollahi A, Simon C (2010) Phenotype-assisted transcriptome analysis identifies FOXM1 downstream from Ras-MKK3-p38 to regulate in vitro cellular invasion. Oncogene 29(10):1519-1530
    • (2010) Oncogene , vol.29 , Issue.10 , pp. 1519-1530
    • Behren, A.1    Muhlen, S.2    Acuna Sanhueza, G.A.3    Schwager, C.4    Plinkert, P.K.5    Huber, P.E.6    Abdollahi, A.7    Simon, C.8
  • 11
    • 0037115605 scopus 로고    scopus 로고
    • Protein kinase CKII regulates the interaction of beta-catenin with alpha-catenin and its protein stability
    • 12432063 1:CAS:528:DC%2BD3sXis1Krsw%3D%3D 10.1242/jcs.00154
    • Bek S, Kemler R (2002) Protein kinase CKII regulates the interaction of beta-catenin with alpha-catenin and its protein stability. J Cell Sci 115(Pt 24):4743-4753
    • (2002) J Cell Sci , vol.115 , Issue.PART 24 , pp. 4743-4753
    • Bek, S.1    Kemler, R.2
  • 14
    • 79959416761 scopus 로고    scopus 로고
    • Arginine methylation of G3BP1 in response to Wnt3a regulates beta-catenin mRNA
    • 21652632 1:CAS:528:DC%2BC3MXpvFelt74%3D 10.1242/jcs.084046
    • Bikkavilli RK, Malbon CC (2011) Arginine methylation of G3BP1 in response to Wnt3a regulates beta-catenin mRNA. J Cell Sci 124(Pt 13):2310-2320
    • (2011) J Cell Sci , vol.124 , Issue.PART 13 , pp. 2310-2320
    • Bikkavilli, R.K.1    Malbon, C.C.2
  • 15
    • 0034662653 scopus 로고    scopus 로고
    • Mutational and nonmutational activation of p21ras in rat colonic azoxymethane-induced tumors: Effects on mitogen-activated protein kinase, cyclooxygenase-2, and cyclin D1
    • 10969813 1:CAS:528:DC%2BD3cXmsVahsL8%3D
    • Bissonnette M, Khare S, von Lintig FC, Wali RK, Nguyen L, Zhang Y, Hart J, Skarosi S, Varki N, Boss GR, Brasitus TA (2000) Mutational and nonmutational activation of p21ras in rat colonic azoxymethane-induced tumors: effects on mitogen-activated protein kinase, cyclooxygenase-2, and cyclin D1. Cancer Res 60(16):4602-4609
    • (2000) Cancer Res , vol.60 , Issue.16 , pp. 4602-4609
    • Bissonnette, M.1    Khare, S.2    Von Lintig, F.C.3    Wali, R.K.4    Nguyen, L.5    Zhang, Y.6    Hart, J.7    Skarosi, S.8    Varki, N.9    Boss, G.R.10    Brasitus, T.A.11
  • 16
    • 54449087431 scopus 로고    scopus 로고
    • C-Myc and its target FoxM1 are critical downstream effectors of constitutive androstane receptor (CAR) mediated direct liver hyperplasia
    • 18798339 1:CAS:528:DC%2BD1cXht1Khu7zO 10.1002/hep.22475
    • Blanco-Bose WE, Murphy MJ, Ehninger A, Offner S, Dubey C, Huang W, Moore DD, Trumpp A (2008) C-Myc and its target FoxM1 are critical downstream effectors of constitutive androstane receptor (CAR) mediated direct liver hyperplasia. Hepatology 48(4):1302-1311
    • (2008) Hepatology , vol.48 , Issue.4 , pp. 1302-1311
    • Blanco-Bose, W.E.1    Murphy, M.J.2    Ehninger, A.3    Offner, S.4    Dubey, C.5    Huang, W.6    Moore, D.D.7    Trumpp, A.8
  • 17
    • 58849105030 scopus 로고    scopus 로고
    • A systems biological approach suggests that transcriptional feedback regulation by dual-specificity phosphatase 6 shapes extracellular signal-related kinase activity in RAS-transformed fibroblasts
    • 19154344 10.1111/j.1742-4658.2008.06846.x 1:CAS:528:DC%2BD1MXitlCkurc%3D
    • Bluthgen N, Legewie S, Kielbasa SM, Schramme A, Tchernitsa O, Keil J, Solf A, Vingron M, Schafer R, Herzel H, Sers C (2009) A systems biological approach suggests that transcriptional feedback regulation by dual-specificity phosphatase 6 shapes extracellular signal-related kinase activity in RAS-transformed fibroblasts. FEBS J 276(4):1024-1035
    • (2009) FEBS J , vol.276 , Issue.4 , pp. 1024-1035
    • Bluthgen, N.1    Legewie, S.2    Kielbasa, S.M.3    Schramme, A.4    Tchernitsa, O.5    Keil, J.6    Solf, A.7    Vingron, M.8    Schafer, R.9    Herzel, H.10    Sers, C.11
  • 18
    • 84865450022 scopus 로고    scopus 로고
    • Aurora B is regulated by the mitogen-activated protein kinase/extracellular signal-regulated kinase (MAPK/ERK) signaling pathway and is a valuable potential target in melanoma cells
    • 22767597 1:CAS:528:DC%2BC38Xht1CgtrvJ 10.1074/jbc.M112.371682
    • Bonet C, Giuliano S, Ohanna M, Bille K, Allegra M, Lacour JP, Bahadoran P, Rocchi S, Ballotti R, Bertolotto C (2012) Aurora B is regulated by the mitogen-activated protein kinase/extracellular signal-regulated kinase (MAPK/ERK) signaling pathway and is a valuable potential target in melanoma cells. J Biol Chem 287(35):29887-29898
    • (2012) J Biol Chem , vol.287 , Issue.35 , pp. 29887-29898
    • Bonet, C.1    Giuliano, S.2    Ohanna, M.3    Bille, K.4    Allegra, M.5    Lacour, J.P.6    Bahadoran, P.7    Rocchi, S.8    Ballotti, R.9    Bertolotto, C.10
  • 19
    • 52449131736 scopus 로고    scopus 로고
    • Cross-talk between aryl hydrocarbon receptor and mitogen-activated protein kinase signaling pathway in liver cancer through c-raf transcriptional regulation
    • 18708364 1:CAS:528:DC%2BD1cXpvVaru7o%3D 10.1158/1541-7786.MCR-08-0042
    • Borlak J, Jenke HS (2008) Cross-talk between aryl hydrocarbon receptor and mitogen-activated protein kinase signaling pathway in liver cancer through c-raf transcriptional regulation. Mol Cancer Res 6(8):1326-1336
    • (2008) Mol Cancer Res , vol.6 , Issue.8 , pp. 1326-1336
    • Borlak, J.1    Jenke, H.S.2
  • 20
    • 0024376173 scopus 로고
    • Ras oncogenes in human cancer: A review
    • 2547513 1:CAS:528:DyaL1MXltlWksL4%3D
    • Bos JL (1989) ras oncogenes in human cancer: a review. Cancer Res 49(17):4682-4689
    • (1989) Cancer Res , vol.49 , Issue.17 , pp. 4682-4689
    • Bos, J.L.1
  • 22
    • 77957234538 scopus 로고    scopus 로고
    • Identification of {beta}-catenin binding regions in colon cancer cells using ChIP-Seq
    • 20460455 1:CAS:528:DC%2BC3cXht1WhsLzE 10.1093/nar/gkq363
    • Bottomly D, Kyler SL, McWeeney SK, Yochum GS (2010) Identification of {beta}-catenin binding regions in colon cancer cells using ChIP-Seq. Nucleic Acids Res 38(17):5735-5745
    • (2010) Nucleic Acids Res , vol.38 , Issue.17 , pp. 5735-5745
    • Bottomly, D.1    Kyler, S.L.2    McWeeney, S.K.3    Yochum, G.S.4
  • 23
    • 80054738983 scopus 로고    scopus 로고
    • Location, location, location: FoxM1 mediates beta-catenin nuclear translocation and promotes glioma tumorigenesis
    • 22014565 1:CAS:528:DC%2BC3MXhtlKrtrnE 10.1016/j.ccr.2011.10.003
    • Bowman A, Nusse R (2011) Location, location, location: FoxM1 mediates beta-catenin nuclear translocation and promotes glioma tumorigenesis. Cancer Cell 20(4):415-416
    • (2011) Cancer Cell , vol.20 , Issue.4 , pp. 415-416
    • Bowman, A.1    Nusse, R.2
  • 24
    • 0032884884 scopus 로고    scopus 로고
    • Beta-catenin regulates the expression of the matrix metalloproteinase-7 in human colorectal cancer
    • 10514384 1:CAS:528:DyaK1MXntFWmsb0%3D 10.1016/S0002-9440(10)65204-2
    • Brabletz T, Jung A, Dag S, Hlubek F, Kirchner T (1999) beta-catenin regulates the expression of the matrix metalloproteinase-7 in human colorectal cancer. Am J Pathol 155(4):1033-1038
    • (1999) Am J Pathol , vol.155 , Issue.4 , pp. 1033-1038
    • Brabletz, T.1    Jung, A.2    Dag, S.3    Hlubek, F.4    Kirchner, T.5
  • 25
    • 65549136561 scopus 로고    scopus 로고
    • Regulation of cytochrome p450 expression by ras- and Beta catenin-dependent signaling
    • 19275549 1:CAS:528:DC%2BD1MXks1SqtLs%3D 10.2174/138920009787522160
    • Braeuning A (2009) Regulation of cytochrome p450 expression by ras- and Beta catenin-dependent signaling. Curr Drug Metab 10(2):138-158
    • (2009) Curr Drug Metab , vol.10 , Issue.2 , pp. 138-158
    • Braeuning, A.1
  • 26
    • 84857564987 scopus 로고    scopus 로고
    • Interplay of beta-catenin with xenobiotic-sensing receptors and its role in glutathione S-transferase expression
    • 22300019 1:CAS:528:DC%2BC38XhsVOntrk%3D 10.2174/138920012798918381
    • Braeuning A (2012) Interplay of beta-catenin with xenobiotic-sensing receptors and its role in glutathione S-transferase expression. Curr Drug Metab 13(2):203-214
    • (2012) Curr Drug Metab , vol.13 , Issue.2 , pp. 203-214
    • Braeuning, A.1
  • 27
    • 77749336635 scopus 로고    scopus 로고
    • Beta-catenin as a multilayer modulator of zonal cytochrome P450 expression in mouse liver
    • 20030591 1:CAS:528:DC%2BC3cXjtVaju7o%3D
    • Braeuning A, Schwarz M (2010) Beta-catenin as a multilayer modulator of zonal cytochrome P450 expression in mouse liver. Biol Chem 391(2-3):139-148
    • (2010) Biol Chem , vol.391 , Issue.2-3 , pp. 139-148
    • Braeuning, A.1    Schwarz, M.2
  • 28
    • 33750536032 scopus 로고    scopus 로고
    • Differential gene expression in periportal and perivenous mouse hepatocytes
    • 17054714 1:CAS:528:DC%2BD28Xht1yqs7%2FF 10.1111/j.1742-4658.2006.05503.x
    • Braeuning A, Ittrich C, Kohle C, Hailfinger S, Bonin M, Buchmann A, Schwarz M (2006) Differential gene expression in periportal and perivenous mouse hepatocytes. FEBS J 273(22):5051-5061
    • (2006) FEBS J , vol.273 , Issue.22 , pp. 5051-5061
    • Braeuning, A.1    Ittrich, C.2    Kohle, C.3    Hailfinger, S.4    Bonin, M.5    Buchmann, A.6    Schwarz, M.7
  • 29
    • 34047157076 scopus 로고    scopus 로고
    • Zonal gene expression in mouse liver resembles expression patterns of Ha-ras and beta-catenin mutated hepatomas
    • 17220236 1:CAS:528:DC%2BD2sXktVOntrY%3D 10.1124/dmd.106.013656
    • Braeuning A, Ittrich C, Kohle C, Buchmann A, Schwarz M (2007a) Zonal gene expression in mouse liver resembles expression patterns of Ha-ras and beta-catenin mutated hepatomas. Drug Metab Dispos 35(4):503-507
    • (2007) Drug Metab Dispos , vol.35 , Issue.4 , pp. 503-507
    • Braeuning, A.1    Ittrich, C.2    Kohle, C.3    Buchmann, A.4    Schwarz, M.5
  • 30
    • 34548458190 scopus 로고    scopus 로고
    • Serum components and activated Ha-ras antagonize expression of perivenous marker genes stimulated by beta-catenin signaling in mouse hepatocytes
    • 17697114 1:CAS:528:DC%2BD2sXhtVyksLrK 10.1111/j.1742-4658.2007.06002.x
    • Braeuning A, Menzel M, Kleinschnitz EM, Harada N, Tamai Y, Kohle C, Buchmann A, Schwarz M (2007b) Serum components and activated Ha-ras antagonize expression of perivenous marker genes stimulated by beta-catenin signaling in mouse hepatocytes. FEBS J 274(18):4766-4777
    • (2007) FEBS J , vol.274 , Issue.18 , pp. 4766-4777
    • Braeuning, A.1    Menzel, M.2    Kleinschnitz, E.M.3    Harada, N.4    Tamai, Y.5    Kohle, C.6    Buchmann, A.7    Schwarz, M.8
  • 31
    • 66449102968 scopus 로고    scopus 로고
    • Inducibility of drug-metabolizing enzymes by xenobiotics in mice with liver-specific knockout of Ctnnb1
    • 19237511 1:CAS:528:DC%2BD1MXlsVWiurs%3D 10.1124/dmd.108.026179
    • Braeuning A, Sanna R, Huelsken J, Schwarz M (2009) Inducibility of drug-metabolizing enzymes by xenobiotics in mice with liver-specific knockout of Ctnnb1. Drug Metab Dispos 37:1138-1145
    • (2009) Drug Metab Dispos , vol.37 , pp. 1138-1145
    • Braeuning, A.1    Sanna, R.2    Huelsken, J.3    Schwarz, M.4
  • 32
    • 80052466189 scopus 로고    scopus 로고
    • Gender-specific interplay of signaling through beta-catenin and CAR in the regulation of xenobiotic-induced hepatocyte proliferation
    • 21705713 1:CAS:528:DC%2BC3MXhtFeiu7rI 10.1093/toxsci/kfr166
    • Braeuning A, Heubach Y, Knorpp T, Kowalik MA, Templin M, Columbano A, Schwarz M (2011a) Gender-specific interplay of signaling through beta-catenin and CAR in the regulation of xenobiotic-induced hepatocyte proliferation. Toxicol Sci 123(1):113-122
    • (2011) Toxicol Sci , vol.123 , Issue.1 , pp. 113-122
    • Braeuning, A.1    Heubach, Y.2    Knorpp, T.3    Kowalik, M.A.4    Templin, M.5    Columbano, A.6    Schwarz, M.7
  • 33
    • 79961004343 scopus 로고    scopus 로고
    • Coordinate regulation of cytochrome P450 1A1 expression in mouse liver by the aryl hydrocarbon receptor and the {beta}-catenin pathway
    • 21498875 1:CAS:528:DC%2BC3MXpslSjs70%3D 10.1093/toxsci/kfr080
    • Braeuning A, Kohle C, Buchmann A, Schwarz M (2011b) Coordinate regulation of cytochrome P450 1A1 expression in mouse liver by the aryl hydrocarbon receptor and the {beta}-catenin pathway. Toxicol Sci 122(1):16-25
    • (2011) Toxicol Sci , vol.122 , Issue.1 , pp. 16-25
    • Braeuning, A.1    Kohle, C.2    Buchmann, A.3    Schwarz, M.4
  • 34
    • 78650674666 scopus 로고    scopus 로고
    • Decorin antagonizes Met receptor activity and down-regulates {beta}-catenin and Myc levels
    • 20974860 1:CAS:528:DC%2BC3cXhs1WisrzF 10.1074/jbc.M110.172841
    • Buraschi S, Pal N, Tyler-Rubinstein N, Owens RT, Neill T, Iozzo RV (2010) Decorin antagonizes Met receptor activity and down-regulates {beta}-catenin and Myc levels. J Biol Chem 285(53):42075-42085
    • (2010) J Biol Chem , vol.285 , Issue.53 , pp. 42075-42085
    • Buraschi, S.1    Pal, N.2    Tyler-Rubinstein, N.3    Owens, R.T.4    Neill, T.5    Iozzo, R.V.6
  • 35
    • 33645218959 scopus 로고    scopus 로고
    • Glycogen synthase kinase 3- and extracellular signal-regulated kinase-dependent phosphorylation of paxillin regulates cytoskeletal rearrangement
    • 16537926 1:CAS:528:DC%2BD28XivFSrt7Y%3D 10.1128/MCB.26.7.2857-2868.2006
    • Cai X, Li M, Vrana J, Schaller MD (2006) Glycogen synthase kinase 3- and extracellular signal-regulated kinase-dependent phosphorylation of paxillin regulates cytoskeletal rearrangement. Mol Cell Biol 26(7):2857-2868
    • (2006) Mol Cell Biol , vol.26 , Issue.7 , pp. 2857-2868
    • Cai, X.1    Li, M.2    Vrana, J.3    Schaller, M.D.4
  • 36
    • 0033970533 scopus 로고    scopus 로고
    • Dual specificity phosphatases: A gene family for control of MAP kinase function
    • 10627275 1:CAS:528:DC%2BD3cXltFKgtA%3D%3D
    • Camps M, Nichols A, Arkinstall S (2000) Dual specificity phosphatases: a gene family for control of MAP kinase function. FASEB J 14(1):6-16
    • (2000) FASEB J , vol.14 , Issue.1 , pp. 6-16
    • Camps, M.1    Nichols, A.2    Arkinstall, S.3
  • 37
    • 77950552463 scopus 로고    scopus 로고
    • Targeting the HGF/Met signalling pathway in cancer
    • 20303741 1:CAS:528:DC%2BC3cXkvFKqtrc%3D 10.1016/j.ejca.2010.02.028
    • Cecchi F, Rabe DC, Bottaro DP (2010) Targeting the HGF/Met signalling pathway in cancer. Eur J Cancer 46(7):1260-1270
    • (2010) Eur J Cancer , vol.46 , Issue.7 , pp. 1260-1270
    • Cecchi, F.1    Rabe, D.C.2    Bottaro, D.P.3
  • 38
    • 84861304952 scopus 로고    scopus 로고
    • Targeting the HGF/Met signaling pathway in cancer therapy
    • 22530990 1:CAS:528:DC%2BC38Xnt1elu70%3D 10.1517/14728222.2012.680957
    • Cecchi F, Rabe DC, Bottaro DP (2012) Targeting the HGF/Met signaling pathway in cancer therapy. Expert Opin Ther Targets 16(6):553-572
    • (2012) Expert Opin Ther Targets , vol.16 , Issue.6 , pp. 553-572
    • Cecchi, F.1    Rabe, D.C.2    Bottaro, D.P.3
  • 39
    • 78751692388 scopus 로고    scopus 로고
    • Mitogen-activated protein kinases promote WNT/beta-catenin signaling via phosphorylation of LRP6
    • 20974802 1:CAS:528:DC%2BC3MXitlCjtrw%3D 10.1128/MCB.00550-10
    • Cervenka I, Wolf J, Masek J, Krejci P, Wilcox WR, Kozubik A, Schulte G, Gutkind JS, Bryja V (2011) Mitogen-activated protein kinases promote WNT/beta-catenin signaling via phosphorylation of LRP6. Mol Cell Biol 31(1):179-189
    • (2011) Mol Cell Biol , vol.31 , Issue.1 , pp. 179-189
    • Cervenka, I.1    Wolf, J.2    Masek, J.3    Krejci, P.4    Wilcox, W.R.5    Kozubik, A.6    Schulte, G.7    Gutkind, J.S.8    Bryja, V.9
  • 40
    • 24344448238 scopus 로고    scopus 로고
    • Synergistic activation of the murine gastrin promoter by oncogenic Ras and beta-catenin involves SMAD recruitment
    • 16139800 1:CAS:528:DC%2BD2MXpvFeiu74%3D 10.1016/j.bbrc.2005.08.061
    • Chakladar A, Dubeykovskiy A, Wojtukiewicz LJ, Pratap J, Lei S, Wang TC (2005) Synergistic activation of the murine gastrin promoter by oncogenic Ras and beta-catenin involves SMAD recruitment. Biochem Biophys Res Commun 336(1):190-196
    • (2005) Biochem Biophys Res Commun , vol.336 , Issue.1 , pp. 190-196
    • Chakladar, A.1    Dubeykovskiy, A.2    Wojtukiewicz, L.J.3    Pratap, J.4    Lei, S.5    Wang, T.C.6
  • 41
    • 1942538298 scopus 로고    scopus 로고
    • Identification of aryl hydrocarbon receptor as a putative Wnt/beta-catenin pathway target gene in prostate cancer cells
    • 15059908 1:CAS:528:DC%2BD2cXis1yjurw%3D 10.1158/0008-5472.CAN-03-3309
    • Chesire DR, Dunn TA, Ewing CM, Luo J, Isaacs WB (2004) Identification of aryl hydrocarbon receptor as a putative Wnt/beta-catenin pathway target gene in prostate cancer cells. Cancer Res 64(7):2523-2533
    • (2004) Cancer Res , vol.64 , Issue.7 , pp. 2523-2533
    • Chesire, D.R.1    Dunn, T.A.2    Ewing, C.M.3    Luo, J.4    Isaacs, W.B.5
  • 42
    • 61449495071 scopus 로고    scopus 로고
    • Serum response factor enhances liver metastasis of colorectal carcinoma via alteration of the E-cadherin/beta-catenin complex
    • 19082443 1:CAS:528:DC%2BD1MXht1Cqt7k%3D
    • Choi HN, Kim KR, Lee JH, Park HS, Jang KY, Chung MJ, Hwang SE, Yu HC, Moon WS (2009) Serum response factor enhances liver metastasis of colorectal carcinoma via alteration of the E-cadherin/beta-catenin complex. Oncol Rep 21(1):57-63
    • (2009) Oncol Rep , vol.21 , Issue.1 , pp. 57-63
    • Choi, H.N.1    Kim, K.R.2    Lee, J.H.3    Park, H.S.4    Jang, K.Y.5    Chung, M.J.6    Hwang, S.E.7    Yu, H.C.8    Moon, W.S.9
  • 43
    • 0037296518 scopus 로고    scopus 로고
    • Wnt1 and Wnt5a induce cyclin D1 expression through ErbB1 transactivation in HC11 mammary epithelial cells
    • 12612606 1:CAS:528:DC%2BD3sXhslSqtb8%3D 10.1038/sj.embor.embor735
    • Civenni G, Holbro T, Hynes NE (2003) Wnt1 and Wnt5a induce cyclin D1 expression through ErbB1 transactivation in HC11 mammary epithelial cells. EMBO Rep 4(2):166-171
    • (2003) EMBO Rep , vol.4 , Issue.2 , pp. 166-171
    • Civenni, G.1    Holbro, T.2    Hynes, N.E.3
  • 44
    • 70649105588 scopus 로고    scopus 로고
    • Integration of the beta-catenin-dependent Wnt pathway with integrin signaling through the adaptor molecule Grb2
    • 19924227 10.1371/journal.pone.0007841 1:CAS:528:DC%2BD1MXhsVKltrbF
    • Crampton SP, Wu B, Park EJ, Kim JH, Solomon C, Waterman ML, Hughes CC (2009) Integration of the beta-catenin-dependent Wnt pathway with integrin signaling through the adaptor molecule Grb2. PLoS ONE 4(11):e7841
    • (2009) PLoS ONE , vol.4 , Issue.11 , pp. 7841
    • Crampton, S.P.1    Wu, B.2    Park, E.J.3    Kim, J.H.4    Solomon, C.5    Waterman, M.L.6    Hughes, C.C.7
  • 45
    • 0027978816 scopus 로고
    • The inhibition of glycogen synthase kinase-3 by insulin or insulin-like growth factor 1 in the rat skeletal muscle cell line L6 is blocked by wortmannin, but not by rapamycin: Evidence that wortmannin blocks activation of the mitogen-activated protein kinase pathway in L6 cells between Ras and Raf
    • 7945242 1:CAS:528:DyaK2cXmtVWktb0%3D
    • Cross DA, Alessi DR, Vandenheede JR, McDowell HE, Hundal HS, Cohen P (1994) The inhibition of glycogen synthase kinase-3 by insulin or insulin-like growth factor 1 in the rat skeletal muscle cell line L6 is blocked by wortmannin, but not by rapamycin: evidence that wortmannin blocks activation of the mitogen-activated protein kinase pathway in L6 cells between Ras and Raf. Biochem J 303(Pt 1):21-26
    • (1994) Biochem J , vol.303 , Issue.PART 1 , pp. 21-26
    • Cross, D.A.1    Alessi, D.R.2    Vandenheede, J.R.3    McDowell, H.E.4    Hundal, H.S.5    Cohen, P.6
  • 46
    • 0035087123 scopus 로고    scopus 로고
    • Selective small-molecule inhibitors of glycogen synthase kinase-3 activity protect primary neurones from death
    • 11279265 1:CAS:528:DC%2BD3MXis1Klt7s%3D 10.1046/j.1471-4159.2001.t01-1- 00251.x
    • Cross DA, Culbert AA, Chalmers KA, Facci L, Skaper SD, Reith AD (2001) Selective small-molecule inhibitors of glycogen synthase kinase-3 activity protect primary neurones from death. J Neurochem 77(1):94-102
    • (2001) J Neurochem , vol.77 , Issue.1 , pp. 94-102
    • Cross, D.A.1    Culbert, A.A.2    Chalmers, K.A.3    Facci, L.4    Skaper, S.D.5    Reith, A.D.6
  • 47
    • 0029670841 scopus 로고    scopus 로고
    • Synergy between Apc min and an activated ras mutation is sufficient to induce colon carcinomas
    • 8622690
    • D'Abaco GM, Whitehead RH, Burgess AW (1996) Synergy between Apc min and an activated ras mutation is sufficient to induce colon carcinomas. Mol Cell Biol 16(3):884-891
    • (1996) Mol Cell Biol , vol.16 , Issue.3 , pp. 884-891
    • D'Abaco, G.M.1    Whitehead, R.H.2    Burgess, A.W.3
  • 52
    • 0035843148 scopus 로고    scopus 로고
    • Insulin and IGF-1 stimulate the beta-catenin pathway through two signalling cascades involving GSK-3beta inhibition and Ras activation
    • 11313952 1:CAS:528:DC%2BD3MXhtFCjsrk%3D 10.1038/sj.onc.1204064
    • Desbois-Mouthon C, Cadoret A, Blivet-Van Eggelpoel MJ, Bertrand F, Cherqui G, Perret C, Capeau J (2001) Insulin and IGF-1 stimulate the beta-catenin pathway through two signalling cascades involving GSK-3beta inhibition and Ras activation. Oncogene 20(2):252-259
    • (2001) Oncogene , vol.20 , Issue.2 , pp. 252-259
    • Desbois-Mouthon, C.1    Cadoret, A.2    Blivet-Van Eggelpoel, M.J.3    Bertrand, F.4    Cherqui, G.5    Perret, C.6    Capeau, J.7
  • 54
    • 0037264633 scopus 로고    scopus 로고
    • Targeting RAS signalling pathways in cancer therapy
    • 12509763 1:CAS:528:DC%2BD38XpvVertbo%3D 10.1038/nrc969
    • Downward J (2003) Targeting RAS signalling pathways in cancer therapy. Nat Rev Cancer 3(1):11-22
    • (2003) Nat Rev Cancer , vol.3 , Issue.1 , pp. 11-22
    • Downward, J.1
  • 55
    • 58749095280 scopus 로고    scopus 로고
    • The nuclear receptors SF1 and LRH1 are expressed in endometrial cancer cells and regulate steroidogenic gene transcription by cooperating with AP-1 factors
    • 19022561 1:CAS:528:DC%2BD1MXhtVeiur4%3D 10.1016/j.canlet.2008.10.008
    • Dube C, Bergeron F, Vaillant MJ, Robert NM, Brousseau C, Tremblay JJ (2009) The nuclear receptors SF1 and LRH1 are expressed in endometrial cancer cells and regulate steroidogenic gene transcription by cooperating with AP-1 factors. Cancer Lett 275(1):127-138
    • (2009) Cancer Lett , vol.275 , Issue.1 , pp. 127-138
    • Dube, C.1    Bergeron, F.2    Vaillant, M.J.3    Robert, N.M.4    Brousseau, C.5    Tremblay, J.J.6
  • 56
    • 0038351827 scopus 로고    scopus 로고
    • Identification of novel ERK2 substrates through use of an engineered kinase and ATP analogs
    • 12594221 1:CAS:528:DC%2BD3sXjtVCmu7o%3D 10.1074/jbc.M300485200
    • Eblen ST, Kumar NV, Shah K, Henderson MJ, Watts CK, Shokat KM, Weber MJ (2003) Identification of novel ERK2 substrates through use of an engineered kinase and ATP analogs. J Biol Chem 278(17):14926-14935
    • (2003) J Biol Chem , vol.278 , Issue.17 , pp. 14926-14935
    • Eblen, S.T.1    Kumar, N.V.2    Shah, K.3    Henderson, M.J.4    Watts, C.K.5    Shokat, K.M.6    Weber, M.J.7
  • 57
    • 44449113769 scopus 로고    scopus 로고
    • Negative-feedback regulation of FGF signalling by DUSP6/MKP-3 is driven by ERK1/2 and mediated by Ets factor binding to a conserved site within the DUSP6/MKP-3 gene promoter
    • 18321244 1:CAS:528:DC%2BD1cXlvVWmtr4%3D 10.1042/BJ20071512
    • Ekerot M, Stavridis MP, Delavaine L, Mitchell MP, Staples C, Owens DM, Keenan ID, Dickinson RJ, Storey KG, Keyse SM (2008) Negative-feedback regulation of FGF signalling by DUSP6/MKP-3 is driven by ERK1/2 and mediated by Ets factor binding to a conserved site within the DUSP6/MKP-3 gene promoter. Biochem J 412(2):287-298
    • (2008) Biochem J , vol.412 , Issue.2 , pp. 287-298
    • Ekerot, M.1    Stavridis, M.P.2    Delavaine, L.3    Mitchell, M.P.4    Staples, C.5    Owens, D.M.6    Keenan, I.D.7    Dickinson, R.J.8    Storey, K.G.9    Keyse, S.M.10
  • 58
    • 0019026208 scopus 로고
    • Glycogen synthase kinase-3 from rabbit skeletal muscle. Separation from cyclic-AMP-dependent protein kinase and phosphorylase kinase
    • 6249596 1:CAS:528:DyaL3cXkvFSrt7Y%3D 10.1111/j.1432-1033.1980.tb06059.x
    • Embi N, Rylatt DB, Cohen P (1980) Glycogen synthase kinase-3 from rabbit skeletal muscle. Separation from cyclic-AMP-dependent protein kinase and phosphorylase kinase. Eur J Biochem 107(2):519-527
    • (1980) Eur J Biochem , vol.107 , Issue.2 , pp. 519-527
    • Embi, N.1    Rylatt, D.B.2    Cohen, P.3
  • 59
    • 0030598390 scopus 로고    scopus 로고
    • Identification of c-Src as the integral component of the cytosolic Ah receptor complex, transducing the signal of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) through the protein phosphorylation pathway
    • 8937476 1:CAS:528:DyaK28XmslWgsb0%3D 10.1016/S0006-2952(96)00566-7
    • Enan E, Matsumura F (1996) Identification of c-Src as the integral component of the cytosolic Ah receptor complex, transducing the signal of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) through the protein phosphorylation pathway. Biochem Pharmacol 52(10):1599-1612
    • (1996) Biochem Pharmacol , vol.52 , Issue.10 , pp. 1599-1612
    • Enan, E.1    Matsumura, F.2
  • 60
    • 33846138978 scopus 로고    scopus 로고
    • Progesterone receptors upregulate Wnt-1 to induce epidermal growth factor receptor transactivation and c-Src-dependent sustained activation of Erk1/2 mitogen-activated protein kinase in breast cancer cells
    • 17074804 1:CAS:528:DC%2BD2sXmvVOmsA%3D%3D 10.1128/MCB.01539-06
    • Faivre EJ, Lange CA (2007) Progesterone receptors upregulate Wnt-1 to induce epidermal growth factor receptor transactivation and c-Src-dependent sustained activation of Erk1/2 mitogen-activated protein kinase in breast cancer cells. Mol Cell Biol 27(2):466-480
    • (2007) Mol Cell Biol , vol.27 , Issue.2 , pp. 466-480
    • Faivre, E.J.1    Lange, C.A.2
  • 61
    • 34249661591 scopus 로고    scopus 로고
    • Phosphorylation of beta-catenin by AKT promotes beta-catenin transcriptional activity
    • 17287208 1:CAS:528:DC%2BD2sXjvFagtr0%3D 10.1074/jbc.M611871200
    • Fang D, Hawke D, Zheng Y, Xia Y, Meisenhelder J, Nika H, Mills GB, Kobayashi R, Hunter T, Lu Z (2007) Phosphorylation of beta-catenin by AKT promotes beta-catenin transcriptional activity. J Biol Chem 282(15):11221-11229
    • (2007) J Biol Chem , vol.282 , Issue.15 , pp. 11221-11229
    • Fang, D.1    Hawke, D.2    Zheng, Y.3    Xia, Y.4    Meisenhelder, J.5    Nika, H.6    Mills, G.B.7    Kobayashi, R.8    Hunter, T.9    Lu, Z.10
  • 62
    • 2342459110 scopus 로고    scopus 로고
    • LRH-1: An orphan nuclear receptor involved in development, metabolism and steroidogenesis
    • 15130581 1:CAS:528:DC%2BD2cXjvVemu74%3D 10.1016/j.tcb.2004.03.008
    • Fayard E, Auwerx J, Schoonjans K (2004) LRH-1: an orphan nuclear receptor involved in development, metabolism and steroidogenesis. Trends Cell Biol 14(5):250-260
    • (2004) Trends Cell Biol , vol.14 , Issue.5 , pp. 250-260
    • Fayard, E.1    Auwerx, J.2    Schoonjans, K.3
  • 63
    • 0025312728 scopus 로고
    • A genetic model for colorectal tumorigenesis
    • 2188735 1:CAS:528:DyaK3cXktlyhtrg%3D 10.1016/0092-8674(90)90186-I
    • Fearon ER, Vogelstein B (1990) A genetic model for colorectal tumorigenesis. Cell 61:759-767
    • (1990) Cell , vol.61 , pp. 759-767
    • Fearon, E.R.1    Vogelstein, B.2
  • 64
    • 0036224749 scopus 로고    scopus 로고
    • The APC gene in colorectal cancer
    • 11978510 1:CAS:528:DC%2BD38XjtVeitbg%3D 10.1016/S0959-8049(02)00040-0
    • Fodde R (2002) The APC gene in colorectal cancer. Eur J Cancer 38(7):867-871
    • (2002) Eur J Cancer , vol.38 , Issue.7 , pp. 867-871
    • Fodde, R.1
  • 65
    • 77953492385 scopus 로고    scopus 로고
    • Nuclear beta-catenin expression and Wnt signalling: In defence of the dogma
    • 20527017 10.1002/path.2718
    • Fodde R, Tomlinson I (2010) Nuclear beta-catenin expression and Wnt signalling: in defence of the dogma. J Pathol 221(3):239-241
    • (2010) J Pathol , vol.221 , Issue.3 , pp. 239-241
    • Fodde, R.1    Tomlinson, I.2
  • 66
    • 34447626493 scopus 로고    scopus 로고
    • Glycogen synthase kinase 3: A key regulator of cellular fate
    • 17530463 1:CAS:528:DC%2BD2sXptFKht7s%3D 10.1007/s00018-007-7045-7
    • Forde JE, Dale TC (2007) Glycogen synthase kinase 3: a key regulator of cellular fate. Cell Mol Life Sci 64(15):1930-1944
    • (2007) Cell Mol Life Sci , vol.64 , Issue.15 , pp. 1930-1944
    • Forde, J.E.1    Dale, T.C.2
  • 67
    • 41549133557 scopus 로고    scopus 로고
    • Nuclear Dvl, c-Jun, beta-catenin, and TCF form a complex leading to stabilization of beta-catenin-TCF interaction
    • 18347071 1:CAS:528:DC%2BD1cXktFGisr4%3D 10.1083/jcb.200710050
    • Gan XQ, Wang JY, Xi Y, Wu ZL, Li YP, Li L (2008) Nuclear Dvl, c-Jun, beta-catenin, and TCF form a complex leading to stabilization of beta-catenin-TCF interaction. J Cell Biol 180(6):1087-1100
    • (2008) J Cell Biol , vol.180 , Issue.6 , pp. 1087-1100
    • Gan, X.Q.1    Wang, J.Y.2    Xi, Y.3    Wu, Z.L.4    Li, Y.P.5    Li, L.6
  • 68
    • 0026326487 scopus 로고
    • Different proliferative responses of periportal and perivenous hepatocytes to EGF
    • 1764070 1:CAS:528:DyaK38Xlt1ehug%3D%3D 10.1016/0006-291X(91)92066-S
    • Gebhardt R, Jonitza D (1991) Different proliferative responses of periportal and perivenous hepatocytes to EGF. Biochem Biophys Res Commun 181(3):1201-1207
    • (1991) Biochem Biophys Res Commun , vol.181 , Issue.3 , pp. 1201-1207
    • Gebhardt, R.1    Jonitza, D.2
  • 69
    • 0027012735 scopus 로고
    • Heterogeneous distribution of the epidermal growth factor receptor in rat liver parenchyma
    • 1484959 1:CAS:528:DyaK3sXltlSltw%3D%3D 10.1016/S0079-6336(11)80092-6
    • Gebhardt R, Marti U (1992) Heterogeneous distribution of the epidermal growth factor receptor in rat liver parenchyma. Prog Histochem Cytochem 26(1-4):164-168
    • (1992) Prog Histochem Cytochem , vol.26 , Issue.1-4 , pp. 164-168
    • Gebhardt, R.1    Marti, U.2
  • 70
    • 79551686173 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling activates and determines hepatic zonal expression of glutathione S-transferases in mouse liver
    • 20118494 1:CAS:528:DC%2BC3cXkvVOgtbs%3D 10.1093/toxsci/kfq033
    • Giera S, Braeuning A, Kohle C, Bursch W, Metzger U, Buchmann A, Schwarz M (2010) Wnt/beta-catenin signaling activates and determines hepatic zonal expression of glutathione S-transferases in mouse liver. Toxicol Sci 115(1):22-33
    • (2010) Toxicol Sci , vol.115 , Issue.1 , pp. 22-33
    • Giera, S.1    Braeuning, A.2    Kohle, C.3    Bursch, W.4    Metzger, U.5    Buchmann, A.6    Schwarz, M.7
  • 71
    • 48449098941 scopus 로고    scopus 로고
    • Grb2 signaling in cell motility and cancer
    • 18620523 1:CAS:528:DC%2BD1cXos1Cht7Y%3D 10.1517/14728222.12.8.1021
    • Giubellino A, Burke TR Jr, Bottaro DP (2008) Grb2 signaling in cell motility and cancer. Expert Opin Ther Targets 12(8):1021-1033
    • (2008) Expert Opin Ther Targets , vol.12 , Issue.8 , pp. 1021-1033
    • Giubellino, A.1    Burke, Jr.T.R.2    Bottaro, D.P.3
  • 72
    • 84869210716 scopus 로고    scopus 로고
    • FoxM1 and Wnt/beta-catenin signaling in glioma stem cells
    • 23139209 1:CAS:528:DC%2BC38Xhs1ynt7vM 10.1158/0008-5472.CAN-12-0953
    • Gong A, Huang S (2012) FoxM1 and Wnt/beta-catenin signaling in glioma stem cells. Cancer Res 72(22):5658-5662
    • (2012) Cancer Res , vol.72 , Issue.22 , pp. 5658-5662
    • Gong, A.1    Huang, S.2
  • 73
    • 77952316612 scopus 로고    scopus 로고
    • De novo synthesis of {beta}-catenin via H-Ras and MEK regulates airway smooth muscle growth
    • 19906679 1:CAS:528:DC%2BC3cXjtFagsb8%3D 10.1096/fj.09-136325
    • Gosens R, Baarsma HA, Heijink IH, Oenema TA, Halayko AJ, Meurs H, Schmidt M (2010) De novo synthesis of {beta}-catenin via H-Ras and MEK regulates airway smooth muscle growth. Faseb J 24(3):757-768
    • (2010) Faseb J , vol.24 , Issue.3 , pp. 757-768
    • Gosens, R.1    Baarsma, H.A.2    Heijink, I.H.3    Oenema, T.A.4    Halayko, A.J.5    Meurs, H.6    Schmidt, M.7
  • 74
    • 40049099291 scopus 로고    scopus 로고
    • Inhibition of GSK3 differentially modulates NF-kappaB, CREB, AP-1 and beta-catenin signaling in hepatocytes, but fails to promote TNF-alpha-induced apoptosis
    • 18261723 10.1016/j.yexcr.2007.12.015 1:CAS:528:DC%2BD1cXivFylsbc%3D
    • Gotschel F, Kern C, Lang S, Sparna T, Markmann C, Schwager J, McNelly S, von Weizsacker F, Laufer S, Hecht A, Merfort I (2008) Inhibition of GSK3 differentially modulates NF-kappaB, CREB, AP-1 and beta-catenin signaling in hepatocytes, but fails to promote TNF-alpha-induced apoptosis. Exp Cell Res 314(6):1351-1366
    • (2008) Exp Cell Res , vol.314 , Issue.6 , pp. 1351-1366
    • Gotschel, F.1    Kern, C.2    Lang, S.3    Sparna, T.4    Markmann, C.5    Schwager, J.6    McNelly, S.7    Von Weizsacker, F.8    Laufer, S.9    Hecht, A.10    Merfort, I.11
  • 75
    • 84876692096 scopus 로고    scopus 로고
    • A complex interplay between Wnt/beta-catenin signalling and the cell cycle in the adult liver
    • 22973520
    • Gougelet A, Colnot S (2012) A complex interplay between Wnt/beta-catenin signalling and the cell cycle in the adult liver. Int J Hepatol 2012:816125
    • (2012) Int J Hepatol , vol.2012 , pp. 816125
    • Gougelet, A.1    Colnot, S.2
  • 76
    • 0346688565 scopus 로고    scopus 로고
    • In vivo evidence in the brain for lithium inhibition of glycogen synthase kinase-3
    • 12942141 1:CAS:528:DC%2BD3sXhtVSqs7jL 10.1038/sj.npp.1300283
    • Gould TD, Chen G, Manji HK (2004) In vivo evidence in the brain for lithium inhibition of glycogen synthase kinase-3. Neuropsychopharmacology 29(1):32-38
    • (2004) Neuropsychopharmacology , vol.29 , Issue.1 , pp. 32-38
    • Gould, T.D.1    Chen, G.2    Manji, H.K.3
  • 77
    • 0034859101 scopus 로고    scopus 로고
    • The multifaceted roles of glycogen synthase kinase 3beta in cellular signaling
    • 11527574 1:CAS:528:DC%2BD3MXmt1yjt7Y%3D 10.1016/S0301-0082(01)00011-9
    • Grimes CA, Jope RS (2001) The multifaceted roles of glycogen synthase kinase 3beta in cellular signaling. Prog Neurobiol 65(4):391-426
    • (2001) Prog Neurobiol , vol.65 , Issue.4 , pp. 391-426
    • Grimes, C.A.1    Jope, R.S.2
  • 78
    • 84859714184 scopus 로고    scopus 로고
    • Wnt/beta-catenin and MAPK signaling: Allies and enemies in different battlefields
    • Guardavaccaro D, Clevers H (2012) Wnt/beta-catenin and MAPK signaling: allies and enemies in different battlefields. Sci Signal 5(219):pe15
    • (2012) Sci Signal , vol.5 , Issue.219
    • Guardavaccaro, D.1    Clevers, H.2
  • 79
    • 0035914440 scopus 로고    scopus 로고
    • Angiotensin II-induced transcriptional activation of the cyclin D1 gene is mediated by Egr-1 in CHO-AT(1A) cells
    • 11502738 1:CAS:528:DC%2BD3MXnvVemtrc%3D 10.1074/jbc.M103862200
    • Guillemot L, Levy A, Raymondjean M, Rothhut B (2001) Angiotensin II-induced transcriptional activation of the cyclin D1 gene is mediated by Egr-1 in CHO-AT(1A) cells. J Biol Chem 276(42):39394-39403
    • (2001) J Biol Chem , vol.276 , Issue.42 , pp. 39394-39403
    • Guillemot, L.1    Levy, A.2    Raymondjean, M.3    Rothhut, B.4
  • 80
    • 33847080898 scopus 로고    scopus 로고
    • Heat treatment induces liver receptor homolog-1 expression in monkey and rat sertoli cells
    • 17170099 1:CAS:528:DC%2BD2sXitlWnsb8%3D 10.1210/en.2006-1004
    • Guo J, Tao SX, Chen M, Shi YQ, Zhang ZQ, Li YC, Zhang XS, Hu ZY, Liu YX (2007) Heat treatment induces liver receptor homolog-1 expression in monkey and rat sertoli cells. Endocrinology 148(3):1255-1265
    • (2007) Endocrinology , vol.148 , Issue.3 , pp. 1255-1265
    • Guo, J.1    Tao, S.X.2    Chen, M.3    Shi, Y.Q.4    Zhang, Z.Q.5    Li, Y.C.6    Zhang, X.S.7    Hu, Z.Y.8    Liu, Y.X.9
  • 81
    • 84856281317 scopus 로고    scopus 로고
    • The elements of human cyclin D1 promoter and regulation involved
    • 22704330 1:CAS:528:DC%2BC3MXhtVels7bP 10.1007/s13148-010-0018-y
    • Guo ZY, Hao XH, Tan FF, Pei X, Shang LM, Jiang XL, Yang F (2011) The elements of human cyclin D1 promoter and regulation involved. Clin Epigenetics 2(2):63-76
    • (2011) Clin Epigenetics , vol.2 , Issue.2 , pp. 63-76
    • Guo, Z.Y.1    Hao, X.H.2    Tan, F.F.3    Pei, X.4    Shang, L.M.5    Jiang, X.L.6    Yang, F.7
  • 82
    • 84861553906 scopus 로고    scopus 로고
    • Mechanism of beta-catenin-mediated transcriptional regulation of epidermal growth factor receptor expression in glycogen synthase kinase 3 beta-inactivated prostate cancer cells
    • 22493441 1:CAS:528:DC%2BC38XnsF2ntLg%3D 10.1074/jbc.M111.324798
    • Guturi KK, Mandal T, Chatterjee A, Sarkar M, Bhattacharya S, Chatterjee U, Ghosh MK (2012) Mechanism of beta-catenin-mediated transcriptional regulation of epidermal growth factor receptor expression in glycogen synthase kinase 3 beta-inactivated prostate cancer cells. J Biol Chem 287(22):18287-18296
    • (2012) J Biol Chem , vol.287 , Issue.22 , pp. 18287-18296
    • Guturi, K.K.1    Mandal, T.2    Chatterjee, A.3    Sarkar, M.4    Bhattacharya, S.5    Chatterjee, U.6    Ghosh, M.K.7
  • 83
    • 33645227117 scopus 로고    scopus 로고
    • Zonal gene expression in murine liver: Lessons from tumors
    • 16496347 1:CAS:528:DC%2BD28XjtVKqsL8%3D 10.1002/hep.21082
    • Hailfinger S, Jaworski M, Braeuning A, Buchmann A, Schwarz M (2006) Zonal gene expression in murine liver: lessons from tumors. Hepatology 43(3):407-414
    • (2006) Hepatology , vol.43 , Issue.3 , pp. 407-414
    • Hailfinger, S.1    Jaworski, M.2    Braeuning, A.3    Buchmann, A.4    Schwarz, M.5
  • 84
    • 84873290930 scopus 로고    scopus 로고
    • Pertussis toxin-sensitive heterotrimeric G(alphai/o) proteins mediate WNT/beta-catenin and WNT/ERK1/2 signaling in mouse primary microglia stimulated with purified WNT-3A
    • doi: 10.1016/j.cellsig.2012.12.006
    • Halleskog C, Schulte G (2013) Pertussis toxin-sensitive heterotrimeric G(alphai/o) proteins mediate WNT/beta-catenin and WNT/ERK1/2 signaling in mouse primary microglia stimulated with purified WNT-3A. Cell Signal. doi: 10.1016/j.cellsig.2012.12.006
    • (2013) Cell Signal.
    • Halleskog, C.1    Schulte, G.2
  • 85
    • 1642535593 scopus 로고    scopus 로고
    • Hepatocarcinogenesis in mice with beta-catenin and Ha-ras gene mutations
    • 14729607 1:CAS:528:DC%2BD2cXkslyqtQ%3D%3D 10.1158/0008-5472.CAN-03-2123
    • Harada N, Oshima H, Katoh M, Tamai Y, Oshima M, Taketo MM (2004) Hepatocarcinogenesis in mice with beta-catenin and Ha-ras gene mutations. Cancer Res 64(1):48-54
    • (2004) Cancer Res , vol.64 , Issue.1 , pp. 48-54
    • Harada, N.1    Oshima, H.2    Katoh, M.3    Tamai, Y.4    Oshima, M.5    Taketo, M.M.6
  • 86
    • 54049122614 scopus 로고    scopus 로고
    • The role of the transcription factor AP-1 in colitis-associated and beta-catenin-dependent intestinal tumorigenesis in mice
    • 18679426 1:CAS:528:DC%2BD1cXht1Cms7vM 10.1038/onc.2008.211
    • Hasselblatt P, Gresh L, Kudo H, Guinea-Viniegra J, Wagner EF (2008) The role of the transcription factor AP-1 in colitis-associated and beta-catenin-dependent intestinal tumorigenesis in mice. Oncogene 27(47):6102-6109
    • (2008) Oncogene , vol.27 , Issue.47 , pp. 6102-6109
    • Hasselblatt, P.1    Gresh, L.2    Kudo, H.3    Guinea-Viniegra, J.4    Wagner, E.F.5
  • 87
    • 79551675617 scopus 로고    scopus 로고
    • The EDD E3 ubiquitin ligase ubiquitinates and up-regulates beta-catenin
    • 21118991 1:CAS:528:DC%2BC3MXitVChsbc%3D 10.1091/mbc.E10-05-0440
    • Hay-Koren A, Caspi M, Zilberberg A, Rosin-Arbesfeld R (2011) The EDD E3 ubiquitin ligase ubiquitinates and up-regulates beta-catenin. Mol Biol Cell 22(3):399-411
    • (2011) Mol Biol Cell , vol.22 , Issue.3 , pp. 399-411
    • Hay-Koren, A.1    Caspi, M.2    Zilberberg, A.3    Rosin-Arbesfeld, R.4
  • 89
    • 12344252237 scopus 로고    scopus 로고
    • AP-1 subunits: Quarrel and harmony among siblings
    • 15564374 1:CAS:528:DC%2BD2MXnvFagsA%3D%3D 10.1242/jcs.01589
    • Hess J, Angel P, Schorpp-Kistner M (2004) AP-1 subunits: quarrel and harmony among siblings. J Cell Sci 117(Pt 25):5965-5973
    • (2004) J Cell Sci , vol.117 , Issue.PART , pp. 5965-5973
    • Hess, J.1    Angel, P.2    Schorpp-Kistner, M.3
  • 90
    • 0030296584 scopus 로고    scopus 로고
    • Dioxin induces transcription of fos and jun genes by Ah receptor-dependent and -independent pathways
    • 8917696 1:CAS:528:DyaK28XmvFGisr0%3D
    • Hoffer A, Chang CY, Puga A (1996) Dioxin induces transcription of fos and jun genes by Ah receptor-dependent and -independent pathways. Toxicol Appl Pharmacol 141(1):238-247
    • (1996) Toxicol Appl Pharmacol , vol.141 , Issue.1 , pp. 238-247
    • Hoffer, A.1    Chang, C.Y.2    Puga, A.3
  • 92
    • 84863230264 scopus 로고    scopus 로고
    • Differential WNT activity in colorectal cancer confers limited tumorigenic potential and is regulated by MAPK signaling
    • 22318865 1:CAS:528:DC%2BC38XktVanu7s%3D 10.1158/0008-5472.CAN-11-3222
    • Horst D, Chen J, Morikawa T, Ogino S, Kirchner T, Shivdasani RA (2012) Differential WNT activity in colorectal cancer confers limited tumorigenic potential and is regulated by MAPK signaling. Cancer Res 72(6):1547-1556
    • (2012) Cancer Res , vol.72 , Issue.6 , pp. 1547-1556
    • Horst, D.1    Chen, J.2    Morikawa, T.3    Ogino, S.4    Kirchner, T.5    Shivdasani, R.A.6
  • 93
    • 0028170977 scopus 로고
    • Beta-catenin mediates the interaction of the cadherin-catenin complex with epidermal growth factor receptor
    • 7962096 1:CAS:528:DyaK2cXmslartLo%3D 10.1083/jcb.127.5.1375
    • Hoschuetzky H, Aberle H, Kemler R (1994) Beta-catenin mediates the interaction of the cadherin-catenin complex with epidermal growth factor receptor. J Cell Biol 127(5):1375-1380
    • (1994) J Cell Biol , vol.127 , Issue.5 , pp. 1375-1380
    • Hoschuetzky, H.1    Aberle, H.2    Kemler, R.3
  • 94
    • 77956471611 scopus 로고    scopus 로고
    • Convergence between Wnt-beta-catenin and EGFR signaling in cancer
    • 20828404 10.1186/1476-4598-9-236 1:CAS:528:DC%2BC3cXhtFyjsb%2FN
    • Hu T, Li C (2010) Convergence between Wnt-beta-catenin and EGFR signaling in cancer. Mol Cancer 9:236
    • (2010) Mol Cancer , vol.9 , pp. 236
    • Hu, T.1    Li, C.2
  • 95
    • 77954617035 scopus 로고    scopus 로고
    • Hepatocyte growth factor induces invasion and migration of ovarian cancer cells by decreasing the expression of E-cadherin, beta-catenin, and caveolin-1
    • 1:CAS:528:DC%2BC3cXhtVSltbzM 10.1002/ar.21147
    • Hu J, Shao S, Song Y, Zhao J, Dong Y, Gong L, Yang P (2010) Hepatocyte growth factor induces invasion and migration of ovarian cancer cells by decreasing the expression of E-cadherin, beta-catenin, and caveolin-1. Anat Rec (Hoboken) 293(7):1134-1139
    • (2010) Anat Rec (Hoboken) , vol.293 , Issue.7 , pp. 1134-1139
    • Hu, J.1    Shao, S.2    Song, Y.3    Zhao, J.4    Dong, Y.5    Gong, L.6    Yang, P.7
  • 97
    • 84864320039 scopus 로고    scopus 로고
    • Hepatocyte growth factor activates Wnt pathway by transcriptional activation of LEF1 to facilitate tumor invasion
    • 22436613 1:CAS:528:DC%2BC38XhtVShsb7O 10.1093/carcin/bgs131
    • Huang FI, Chen YL, Chang CN, Yuan RH, Jeng YM (2012) Hepatocyte growth factor activates Wnt pathway by transcriptional activation of LEF1 to facilitate tumor invasion. Carcinogenesis 33(6):1142-1148
    • (2012) Carcinogenesis , vol.33 , Issue.6 , pp. 1142-1148
    • Huang, F.I.1    Chen, Y.L.2    Chang, C.N.3    Yuan, R.H.4    Jeng, Y.M.5
  • 98
    • 84870331037 scopus 로고    scopus 로고
    • Beta-Catenin and peroxisome proliferator-activated receptor-delta coordinate dynamic chromatin loops for the transcription of vascular endothelial growth factor a gene in colon cancer cells
    • 23086933 1:CAS:528:DC%2BC38XhslGjsL%2FM 10.1074/jbc.M112.377739
    • Hwang I, Kim J, Jeong S (2012) Beta-Catenin and peroxisome proliferator-activated receptor-delta coordinate dynamic chromatin loops for the transcription of vascular endothelial growth factor a gene in colon cancer cells. J Biol Chem 287(49):41364-41373
    • (2012) J Biol Chem , vol.287 , Issue.49 , pp. 41364-41373
    • Hwang, I.1    Kim, J.2    Jeong, S.3
  • 100
    • 34548056147 scopus 로고    scopus 로고
    • Global gene expression in Ha-ras and B-raf mutated mouse liver tumors
    • 17514646 1:CAS:528:DC%2BD2sXhtVSmtL%2FF 10.1002/ijc.22801
    • Jaworski M, Ittrich C, Hailfinger S, Bonin M, Buchmann A, Schwarz M, Kohle C (2007) Global gene expression in Ha-ras and B-raf mutated mouse liver tumors. Int J Cancer 121(6):1382-1385
    • (2007) Int J Cancer , vol.121 , Issue.6 , pp. 1382-1385
    • Jaworski, M.1    Ittrich, C.2    Hailfinger, S.3    Bonin, M.4    Buchmann, A.5    Schwarz, M.6    Kohle, C.7
  • 101
    • 34347231979 scopus 로고    scopus 로고
    • Axin inhibits extracellular signal-regulated kinase pathway by Ras degradation via beta-catenin
    • 17374607 1:CAS:528:DC%2BD2sXkvVyntrs%3D 10.1074/jbc.M611129200
    • Jeon SH, Yoon JY, Park YN, Jeong WJ, Kim S, Jho EH, Surh YJ, Choi KY (2007) Axin inhibits extracellular signal-regulated kinase pathway by Ras degradation via beta-catenin. J Biol Chem 282(19):14482-14492
    • (2007) J Biol Chem , vol.282 , Issue.19 , pp. 14482-14492
    • Jeon, S.H.1    Yoon, J.Y.2    Park, Y.N.3    Jeong, W.J.4    Kim, S.5    Jho, E.H.6    Surh, Y.J.7    Choi, K.Y.8
  • 102
  • 103
    • 0036148208 scopus 로고    scopus 로고
    • Wnt/beta-catenin/Tcf signaling induces the transcription of Axin2, a negative regulator of the signaling pathway
    • 11809808 1:CAS:528:DC%2BD38XovVWqtg%3D%3D 10.1128/MCB.22.4.1172-1183.2002
    • Jho EH, Zhang T, Domon C, Joo CK, Freund JN, Costantini F (2002) Wnt/beta-catenin/Tcf signaling induces the transcription of Axin2, a negative regulator of the signaling pathway. Mol Cell Biol 22(4):1172-1183
    • (2002) Mol Cell Biol , vol.22 , Issue.4 , pp. 1172-1183
    • Jho, E.H.1    Zhang, T.2    Domon, C.3    Joo, C.K.4    Freund, J.N.5    Costantini, F.6
  • 104
    • 70449657727 scopus 로고    scopus 로고
    • EGF-induced ERK activation promotes CK2-mediated disassociation of alpha-Catenin from beta-Catenin and transactivation of beta-Catenin
    • 19941816 1:CAS:528:DC%2BC3cXksFWnsA%3D%3D 10.1016/j.molcel.2009.09.034
    • Ji H, Wang J, Nika H, Hawke D, Keezer S, Ge Q, Fang B, Fang X, Fang D, Litchfield DW, Aldape K, Lu Z (2009) EGF-induced ERK activation promotes CK2-mediated disassociation of alpha-Catenin from beta-Catenin and transactivation of beta-Catenin. Mol Cell 36(4):547-559
    • (2009) Mol Cell , vol.36 , Issue.4 , pp. 547-559
    • Ji, H.1    Wang, J.2    Nika, H.3    Hawke, D.4    Keezer, S.5    Ge, Q.6    Fang, B.7    Fang, X.8    Fang, D.9    Litchfield, D.W.10    Aldape, K.11    Lu, Z.12
  • 105
    • 28844472836 scopus 로고    scopus 로고
    • Role for mitogen-activated protein kinases in phenobarbital-induced expression of cytochrome P450 2B in primary cultures of rat hepatocytes
    • 16154717 1:CAS:528:DC%2BD2MXht12ku7jE 10.1016/j.toxlet.2005.08.006
    • Joannard F, Rissel M, Gilot D, Anderson A, Orfila-Lefeuvre L, Guillouzo A, Atfi A, Lagadic-Gossmann D (2006) Role for mitogen-activated protein kinases in phenobarbital-induced expression of cytochrome P450 2B in primary cultures of rat hepatocytes. Toxicol Lett 161(1):61-72
    • (2006) Toxicol Lett , vol.161 , Issue.1 , pp. 61-72
    • Joannard, F.1    Rissel, M.2    Gilot, D.3    Anderson, A.4    Orfila-Lefeuvre, L.5    Guillouzo, A.6    Atfi, A.7    Lagadic-Gossmann, D.8
  • 106
    • 0442276554 scopus 로고    scopus 로고
    • The glamour and gloom of glycogen synthase kinase-3
    • 15102436 1:CAS:528:DC%2BD2cXhtVOrtro%3D 10.1016/j.tibs.2003.12.004
    • Jope RS, Johnson GV (2004) The glamour and gloom of glycogen synthase kinase-3. Trends Biochem Sci 29(2):95-102
    • (2004) Trends Biochem Sci , vol.29 , Issue.2 , pp. 95-102
    • Jope, R.S.1    Johnson, G.V.2
  • 107
    • 33947597084 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3 (GSK3): Inflammation, diseases, and therapeutics
    • 16944320 1:CAS:528:DC%2BD2sXjtlynu7w%3D 10.1007/s11064-006-9128-5
    • Jope RS, Yuskaitis CJ, Beurel E (2007) Glycogen synthase kinase-3 (GSK3): inflammation, diseases, and therapeutics. Neurochem Res 32(4-5):577-595
    • (2007) Neurochem Res , vol.32 , Issue.4-5 , pp. 577-595
    • Jope, R.S.1    Yuskaitis, C.J.2    Beurel, E.3
  • 108
    • 60749116342 scopus 로고    scopus 로고
    • Valproic acid induces differentiation and inhibition of proliferation in neural progenitor cells via the beta-catenin-Ras-ERK-p21Cip/WAF1 pathway
    • 19068119 10.1186/1471-2121-9-66 1:CAS:528:DC%2BD1MXhslGiurc%3D
    • Jung GA, Yoon JY, Moon BS, Yang DH, Kim HY, Lee SH, Bryja V, Arenas E, Choi KY (2008) Valproic acid induces differentiation and inhibition of proliferation in neural progenitor cells via the beta-catenin-Ras-ERK-p21Cip/ WAF1 pathway. BMC Cell Biol 9:66
    • (2008) BMC Cell Biol , vol.9 , pp. 66
    • Jung, G.A.1    Yoon, J.Y.2    Moon, B.S.3    Yang, D.H.4    Kim, H.Y.5    Lee, S.H.6    Bryja, V.7    Arenas, E.8    Choi, K.Y.9
  • 109
    • 79851492288 scopus 로고    scopus 로고
    • Multiple faces of FoxM1 transcription factor: Lessons from transgenic mouse models
    • 21270518 1:CAS:528:DC%2BC3MXjtVSju7w%3D 10.4161/cc.10.3.14709
    • Kalin TV, Ustiyan V, Kalinichenko VV (2011) Multiple faces of FoxM1 transcription factor: lessons from transgenic mouse models. Cell Cycle 10(3):396-405
    • (2011) Cell Cycle , vol.10 , Issue.3 , pp. 396-405
    • Kalin, T.V.1    Ustiyan, V.2    Kalinichenko, V.V.3
  • 110
    • 20344387465 scopus 로고    scopus 로고
    • Active Src elevates the expression of beta-catenin by enhancement of cap-dependent translation
    • 15923620 1:CAS:528:DC%2BD2MXlt1Ortbs%3D 10.1128/MCB.25.12.5031-5039.2005
    • Karni R, Gus Y, Dor Y, Meyuhas O, Levitzki A (2005) Active Src elevates the expression of beta-catenin by enhancement of cap-dependent translation. Mol Cell Biol 25(12):5031-5039
    • (2005) Mol Cell Biol , vol.25 , Issue.12 , pp. 5031-5039
    • Karni, R.1    Gus, Y.2    Dor, Y.3    Meyuhas, O.4    Levitzki, A.5
  • 112
    • 69249101626 scopus 로고    scopus 로고
    • Adenomatous polyposis coli and Asef function downstream of hepatocyte growth factor and phosphatidylinositol 3-kinase
    • 19525225 1:CAS:528:DC%2BD1MXpsFymu7g%3D 10.1074/jbc.M109.020768
    • Kawasaki Y, Tsuji S, Sagara M, Echizen K, Shibata Y, Akiyama T (2009) Adenomatous polyposis coli and Asef function downstream of hepatocyte growth factor and phosphatidylinositol 3-kinase. J Biol Chem 284(33):22436-22443
    • (2009) J Biol Chem , vol.284 , Issue.33 , pp. 22436-22443
    • Kawasaki, Y.1    Tsuji, S.2    Sagara, M.3    Echizen, K.4    Shibata, Y.5    Akiyama, T.6
  • 113
    • 74049123198 scopus 로고    scopus 로고
    • The adenomatous polyposis coli-associated guanine nucleotide exchange factor Asef is involved in angiogenesis
    • 19897489 1:CAS:528:DC%2BC3cXkvFWl 10.1074/jbc.M109.040691
    • Kawasaki Y, Jigami T, Furukawa S, Sagara M, Echizen K, Shibata Y, Sato R, Akiyama T (2010) The adenomatous polyposis coli-associated guanine nucleotide exchange factor Asef is involved in angiogenesis. J Biol Chem 285(2):1199-1207
    • (2010) J Biol Chem , vol.285 , Issue.2 , pp. 1199-1207
    • Kawasaki, Y.1    Jigami, T.2    Furukawa, S.3    Sagara, M.4    Echizen, K.5    Shibata, Y.6    Sato, R.7    Akiyama, T.8
  • 114
    • 34249301021 scopus 로고    scopus 로고
    • EGF receptor is involved in WNT3a-mediated proliferation and motility of NIH3T3 cells via ERK pathway activation
    • 17374561 1:CAS:528:DC%2BD2sXmtVGgsLw%3D 10.1016/j.cellsig.2007.02.003
    • Kim SE, Choi KY (2007) EGF receptor is involved in WNT3a-mediated proliferation and motility of NIH3T3 cells via ERK pathway activation. Cell Signal 19(7):1554-1564
    • (2007) Cell Signal , vol.19 , Issue.7 , pp. 1554-1564
    • Kim, S.E.1    Choi, K.Y.2
  • 115
    • 34447122100 scopus 로고    scopus 로고
    • A hidden oncogenic positive feedback loop caused by crosstalk between Wnt and ERK pathways
    • 17237813 1:CAS:528:DC%2BD2sXnt1entLw%3D 10.1038/sj.onc.1210230
    • Kim D, Rath O, Kolch W, Cho KH (2007) A hidden oncogenic positive feedback loop caused by crosstalk between Wnt and ERK pathways. Oncogene 26(31):4571-4579
    • (2007) Oncogene , vol.26 , Issue.31 , pp. 4571-4579
    • Kim, D.1    Rath, O.2    Kolch, W.3    Cho, K.H.4
  • 116
    • 70349758510 scopus 로고    scopus 로고
    • Src kinases as therapeutic targets for cancer
    • 19787002 10.1038/nrclinonc.2009.129 1:CAS:528:DC%2BD1MXhtFyntbbP
    • Kim LC, Song L, Haura EB (2009a) Src kinases as therapeutic targets for cancer. Nat Rev Clin Oncol 6(10):587-595
    • (2009) Nat Rev Clin Oncol , vol.6 , Issue.10 , pp. 587-595
    • Kim, L.C.1    Song, L.2    Haura, E.B.3
  • 117
    • 66949151103 scopus 로고    scopus 로고
    • H-Ras is degraded by Wnt/beta-catenin signaling via beta-TrCP-mediated polyubiquitylation
    • 19240121 1:CAS:528:DC%2BD1MXksFWqs74%3D 10.1242/jcs.040493
    • Kim SE, Yoon JY, Jeong WJ, Jeon SH, Park Y, Yoon JB, Park YN, Kim H, Choi KY (2009b) H-Ras is degraded by Wnt/beta-catenin signaling via beta-TrCP-mediated polyubiquitylation. J Cell Sci 122(Pt 6):842-848
    • (2009) J Cell Sci , vol.122 , Issue.PART 6 , pp. 842-848
    • Kim, S.E.1    Yoon, J.Y.2    Jeong, W.J.3    Jeon, S.H.4    Park, Y.5    Yoon, J.B.6    Park, Y.N.7    Kim, H.8    Choi, K.Y.9
  • 118
    • 84875723571 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling is a key downstream mediator of MET signaling in glioblastoma stem cells
    • 23258844 1:CAS:528:DC%2BC3sXhsVOnu74%3D 10.1093/neuonc/nos299
    • Kim KH, Seol HJ, Kim EH, Rheey J, Jin HJ, Lee Y, Joo KM, Lee J, Nam DH (2013) Wnt/beta-catenin signaling is a key downstream mediator of MET signaling in glioblastoma stem cells. Neuro Oncol 15(2):161-171
    • (2013) Neuro Oncol , vol.15 , Issue.2 , pp. 161-171
    • Kim, K.H.1    Seol, H.J.2    Kim, E.H.3    Rheey, J.4    Jin, H.J.5    Lee, Y.6    Joo, K.M.7    Lee, J.8    Nam, D.H.9
  • 119
    • 0030592517 scopus 로고    scopus 로고
    • Lessons from hereditary colorectal cancer
    • 8861899 1:CAS:528:DyaK28XmsVGhs7g%3D 10.1016/S0092-8674(00)81333-1
    • Kinzler KW, Vogelstein B (1996) Lessons from hereditary colorectal cancer. Cell 87(2):159-170
    • (1996) Cell , vol.87 , Issue.2 , pp. 159-170
    • Kinzler, K.W.1    Vogelstein, B.2
  • 120
    • 34247505536 scopus 로고    scopus 로고
    • Extracellular signal-regulated kinase is an endogenous signal retaining the nuclear constitutive active/androstane receptor (CAR) in the cytoplasm of mouse primary hepatocytes
    • 17314319 1:CAS:528:DC%2BD2sXlslSju7g%3D 10.1124/mol.107.034538
    • Koike C, Moore R, Negishi M (2007) Extracellular signal-regulated kinase is an endogenous signal retaining the nuclear constitutive active/androstane receptor (CAR) in the cytoplasm of mouse primary hepatocytes. Mol Pharmacol 71(5):1217-1221
    • (2007) Mol Pharmacol , vol.71 , Issue.5 , pp. 1217-1221
    • Koike, C.1    Moore, R.2    Negishi, M.3
  • 121
    • 81055137232 scopus 로고    scopus 로고
    • FOXM1: From cancer initiation to progression and treatment
    • 21978825 1:CAS:528:DC%2BC38XhsVeltw%3D%3D 10.1016/j.bbagrm.2011.09.004
    • Koo CY, Muir KW, Lam EW (2012) FOXM1: from cancer initiation to progression and treatment. Biochim Biophys Acta 1819(1):28-37
    • (2012) Biochim Biophys Acta , vol.1819 , Issue.1 , pp. 28-37
    • Koo, C.Y.1    Muir, K.W.2    Lam, E.W.3
  • 123
    • 33646379618 scopus 로고    scopus 로고
    • Phosphorylation of the hinge domain of the nuclear hormone receptor LRH-1 stimulates transactivation
    • 16439367 1:CAS:528:DC%2BD28Xitl2kt7w%3D 10.1074/jbc.M509115200
    • Lee YK, Choi YH, Chua S, Park YJ, Moore DD (2006) Phosphorylation of the hinge domain of the nuclear hormone receptor LRH-1 stimulates transactivation. J Biol Chem 281(12):7850-7855
    • (2006) J Biol Chem , vol.281 , Issue.12 , pp. 7850-7855
    • Lee, Y.K.1    Choi, Y.H.2    Chua, S.3    Park, Y.J.4    Moore, D.D.5
  • 124
    • 77952302757 scopus 로고    scopus 로고
    • Epidermal growth factor receptor regulates beta-catenin location, stability, and transcriptional activity in oral cancer
    • 20302655 1:CAS:528:DC%2BC3cXjvFOlsLg%3D 10.1186/1476-4598-9-64
    • Lee CH, Hung HW, Hung PH, Shieh YS (2010) Epidermal growth factor receptor regulates beta-catenin location, stability, and transcriptional activity in oral cancer. Mol Cancer 9:64
    • (2010) Mol Cancer , vol.9 , pp. 64
    • Lee, C.H.1    Hung, H.W.2    Hung, P.H.3    Shieh, Y.S.4
  • 125
    • 0346728740 scopus 로고    scopus 로고
    • Cloning of the rat beta-catenin gene (Ctnnb1) promoter and its functional analysis compared with the Catnb and CTNNB1 promoters
    • 14706452 1:CAS:528:DC%2BD2cXksFaq 10.1016/j.ygeno.2003.08.004
    • Li Q, Dashwood WM, Zhong X, Al-Fageeh M, Dashwood RH (2004) Cloning of the rat beta-catenin gene (Ctnnb1) promoter and its functional analysis compared with the Catnb and CTNNB1 promoters. Genomics 83(2):231-242
    • (2004) Genomics , vol.83 , Issue.2 , pp. 231-242
    • Li, Q.1    Dashwood, W.M.2    Zhong, X.3    Al-Fageeh, M.4    Dashwood, R.H.5
  • 126
    • 20444449617 scopus 로고    scopus 로고
    • Oncogenic K-ras stimulates Wnt signaling in colon cancer through inhibition of GSK-3beta
    • 15940626 1:CAS:528:DC%2BD2MXlvFKlsb8%3D 10.1053/j.gastro.2005.02.067
    • Li J, Mizukami Y, Zhang X, Jo WS, Chung DC (2005) Oncogenic K-ras stimulates Wnt signaling in colon cancer through inhibition of GSK-3beta. Gastroenterology 128(7):1907-1918
    • (2005) Gastroenterology , vol.128 , Issue.7 , pp. 1907-1918
    • Li, J.1    Mizukami, Y.2    Zhang, X.3    Jo, W.S.4    Chung, D.C.5
  • 127
    • 33846472047 scopus 로고    scopus 로고
    • Dusp6 (Mkp3) is a negative feedback regulator of FGF-stimulated ERK signaling during mouse development
    • 17164422 1:CAS:528:DC%2BD2sXhsFartb4%3D 10.1242/dev.02701
    • Li C, Scott DA, Hatch E, Tian X, Mansour SL (2007) Dusp6 (Mkp3) is a negative feedback regulator of FGF-stimulated ERK signaling during mouse development. Development 134(1):167-176
    • (2007) Development , vol.134 , Issue.1 , pp. 167-176
    • Li, C.1    Scott, D.A.2    Hatch, E.3    Tian, X.4    Mansour, S.L.5
  • 128
    • 77950511064 scopus 로고    scopus 로고
    • Effects of K-ras gene mutation on colon cancer cell line Caco-2 metastasis by regulating E-cadherin/beta-catenin/p120 protein complex formation and RhoA protein activity
    • 20236587
    • Li JN, Li X, Qian JM, Lu XQ, Yang H (2010) Effects of K-ras gene mutation on colon cancer cell line Caco-2 metastasis by regulating E-cadherin/beta- catenin/p120 protein complex formation and RhoA protein activity. Zhongguo Yi Xue Ke Xue Yuan Xue Bao 32(1):46-50
    • (2010) Zhongguo Yi Xue Ke Xue Yuan Xue Bao , vol.32 , Issue.1 , pp. 46-50
    • Li, J.N.1    Li, X.2    Qian, J.M.3    Lu, X.Q.4    Yang, H.5
  • 129
    • 42449105648 scopus 로고    scopus 로고
    • Homozygous deletion of glycogen synthase kinase 3beta bypasses senescence allowing Ras transformation of primary murine fibroblasts
    • 18367674 1:CAS:528:DC%2BD1cXksVOitro%3D 10.1073/pnas.0704242105
    • Liu S, Fang X, Hall H, Yu S, Smith D, Lu Z, Fang D, Liu J, Stephens LC, Woodgett JR, Mills GB (2008) Homozygous deletion of glycogen synthase kinase 3beta bypasses senescence allowing Ras transformation of primary murine fibroblasts. Proc Natl Acad Sci USA 105(13):5248-5253
    • (2008) Proc Natl Acad Sci USA , vol.105 , Issue.13 , pp. 5248-5253
    • Liu, S.1    Fang, X.2    Hall, H.3    Yu, S.4    Smith, D.5    Lu, Z.6    Fang, D.7    Liu, J.8    Stephens, L.C.9    Woodgett, J.R.10    Mills, G.B.11
  • 130
    • 13444304475 scopus 로고    scopus 로고
    • A beta-catenin-dependent pathway regulates expression of cytochrome P450 isoforms in mouse liver tumors
    • 15471898 1:CAS:528:DC%2BD2MXisVSmtQ%3D%3D 10.1093/carcin/bgh298
    • Loeppen S, Koehle C, Buchmann A, Schwarz M (2005) A beta-catenin- dependent pathway regulates expression of cytochrome P450 isoforms in mouse liver tumors. Carcinogenesis 26:239-248
    • (2005) Carcinogenesis , vol.26 , pp. 239-248
    • Loeppen, S.1    Koehle, C.2    Buchmann, A.3    Schwarz, M.4
  • 131
    • 0027239613 scopus 로고
    • Function and regulation of ras
    • 8352603 1:CAS:528:DyaK3sXlsFCjuro%3D 10.1146/annurev.bi.62.070193.004223
    • Lowy DR, Willumsen BM (1993) Function and regulation of ras. Annu Rev Biochem 62:851-891
    • (1993) Annu Rev Biochem , vol.62 , pp. 851-891
    • Lowy, D.R.1    Willumsen, B.M.2
  • 132
    • 70349324516 scopus 로고    scopus 로고
    • Mutated K-ras(Asp12) promotes tumourigenesis in Apc(Min) mice more in the large than the small intestines, with synergistic effects between K-ras and Wnt pathways
    • 19765110 1:CAS:528:DC%2BD1MXhtlGgu7%2FF 10.1111/j.1365-2613.2009.00667.x
    • Luo F, Brooks DG, Ye H, Hamoudi R, Poulogiannis G, Patek CE, Winton DJ, Arends MJ (2009) Mutated K-ras(Asp12) promotes tumourigenesis in Apc(Min) mice more in the large than the small intestines, with synergistic effects between K-ras and Wnt pathways. Int J Exp Pathol 90(5):558-574
    • (2009) Int J Exp Pathol , vol.90 , Issue.5 , pp. 558-574
    • Luo, F.1    Brooks, D.G.2    Ye, H.3    Hamoudi, R.4    Poulogiannis, G.5    Patek, C.E.6    Winton, D.J.7    Arends, M.J.8
  • 134
    • 14944357408 scopus 로고    scopus 로고
    • Raf/MEK/MAPK signaling stimulates the nuclear translocation and transactivating activity of FOXM1c
    • 15671063 1:CAS:528:DC%2BD2MXislOhsbs%3D 10.1242/jcs.01657
    • Ma RY, Tong TH, Cheung AM, Tsang AC, Leung WY, Yao KM (2005) Raf/MEK/MAPK signaling stimulates the nuclear translocation and transactivating activity of FOXM1c. J Cell Sci 118(Pt 4):795-806
    • (2005) J Cell Sci , vol.118 , Issue.PART 4 , pp. 795-806
    • Ma, R.Y.1    Tong, T.H.2    Cheung, A.M.3    Tsang, A.C.4    Leung, W.Y.5    Yao, K.M.6
  • 135
    • 84934439368 scopus 로고    scopus 로고
    • Raf/MEK/MAPK signaling stimulates the nuclear translocation and transactivating activity of FOXM1
    • 20694663 1:CAS:528:DC%2BC3cXhtVSlu7jL 10.1007/978-1-60761-738-9-6
    • Ma RY, Tong TH, Leung WY, Yao KM (2010) Raf/MEK/MAPK signaling stimulates the nuclear translocation and transactivating activity of FOXM1. Methods Mol Biol 647:113-123
    • (2010) Methods Mol Biol , vol.647 , pp. 113-123
    • Ma, R.Y.1    Tong, T.H.2    Leung, W.Y.3    Yao, K.M.4
  • 137
    • 0025866224 scopus 로고
    • Acinar heterogeneity of the epidermal growth factor receptor in the liver of male rats
    • 1915412 1:CAS:528:DyaK3MXlvF2mt7Y%3D
    • Marti U, Gebhardt R (1991) Acinar heterogeneity of the epidermal growth factor receptor in the liver of male rats. Eur J Cell Biol 55(1):158-164
    • (1991) Eur J Cell Biol , vol.55 , Issue.1 , pp. 158-164
    • Marti, U.1    Gebhardt, R.2
  • 139
    • 0034722889 scopus 로고    scopus 로고
    • The EGF receptor family as targets for cancer therapy
    • 11426640 1:CAS:528:DC%2BD3MXhsF2ku7k%3D 10.1038/sj.onc.1204082
    • Mendelsohn J, Baselga J (2000) The EGF receptor family as targets for cancer therapy. Oncogene 19(56):6550-6565
    • (2000) Oncogene , vol.19 , Issue.56 , pp. 6550-6565
    • Mendelsohn, J.1    Baselga, J.2
  • 141
    • 0032525836 scopus 로고    scopus 로고
    • Activation of the beta-catenin gene in primary hepatocellular carcinomas by somatic alterations involving exon 3
    • 9635572 1:CAS:528:DyaK1cXktVajt7o%3D
    • Miyoshi Y, Iwao K, Nagasawa Y, Aihara T, Sasaki Y, Imaoka S, Murata M, Shimano T, Nakamura Y (1998) Activation of the beta-catenin gene in primary hepatocellular carcinomas by somatic alterations involving exon 3. Cancer Res 58(12):2524-2527
    • (1998) Cancer Res , vol.58 , Issue.12 , pp. 2524-2527
    • Miyoshi, Y.1    Iwao, K.2    Nagasawa, Y.3    Aihara, T.4    Sasaki, Y.5    Imaoka, S.6    Murata, M.7    Shimano, T.8    Nakamura, Y.9
  • 142
    • 0036144406 scopus 로고    scopus 로고
    • Wnt-1 but not epidermal growth factor induces beta-catenin/T-cell factor-dependent transcription in esophageal cancer cells
    • 11782388 1:CAS:528:DC%2BD38XntV2gsA%3D%3D
    • Mizushima T, Nakagawa H, Kamberov YG, Wilder EL, Klein PS, Rustgi AK (2002) Wnt-1 but not epidermal growth factor induces beta-catenin/T-cell factor-dependent transcription in esophageal cancer cells. Cancer Res 62(1):277-282
    • (2002) Cancer Res , vol.62 , Issue.1 , pp. 277-282
    • Mizushima, T.1    Nakagawa, H.2    Kamberov, Y.G.3    Wilder, E.L.4    Klein, P.S.5    Rustgi, A.K.6
  • 143
    • 70449106252 scopus 로고    scopus 로고
    • Thioredoxin regulates cell cycle via the ERK1/2-cyclin D1 pathway
    • Mochizuki M, Kwon YW, Yodoi J, Masutani H (2009) Thioredoxin regulates cell cycle via the ERK1/2-cyclin D1 pathway. Antioxid Redox Signal 11(12):2957-2971
    • (2009) Antioxid Redox Signal , vol.11 , Issue.12 , pp. 2957-2971
    • Mochizuki, M.1    Kwon, Y.W.2    Yodoi, J.3    Masutani, H.4
  • 144
    • 77956904030 scopus 로고    scopus 로고
    • Colorectal tumors are effectively eradicated by combined inhibition of {beta}-catenin, KRAS, and the oncogenic transcription factor ITF2
    • 20823162 1:CAS:528:DC%2BC3cXhtFGqtrjO 10.1158/0008-5472.CAN-10-1108
    • Mologni L, Dekhil H, Ceccon M, Purgante S, Lan C, Cleris L, Magistroni V, Formelli F, Gambacorti-Passerini CB (2010) Colorectal tumors are effectively eradicated by combined inhibition of {beta}-catenin, KRAS, and the oncogenic transcription factor ITF2. Cancer Res 70(18):7253-7263
    • (2010) Cancer Res , vol.70 , Issue.18 , pp. 7253-7263
    • Mologni, L.1    Dekhil, H.2    Ceccon, M.3    Purgante, S.4    Lan, C.5    Cleris, L.6    Magistroni, V.7    Formelli, F.8    Gambacorti-Passerini, C.B.9
  • 145
    • 84870846269 scopus 로고    scopus 로고
    • Synergistic effects of combined Wnt/KRAS inhibition in colorectal cancer cells
    • 23227266 1:CAS:528:DC%2BC38XhvVyhu7rM 10.1371/journal.pone.0051449
    • Mologni L, Brussolo S, Ceccon M, Gambacorti-Passerini C (2012) Synergistic effects of combined Wnt/KRAS inhibition in colorectal cancer cells. PLoS ONE 7(12):e51449
    • (2012) PLoS ONE , vol.7 , Issue.12 , pp. 51449
    • Mologni, L.1    Brussolo, S.2    Ceccon, M.3    Gambacorti-Passerini, C.4
  • 146
    • 0036531819 scopus 로고    scopus 로고
    • Hepatocyte growth factor induces Wnt-independent nuclear translocation of beta-catenin after Met-beta-catenin dissociation in hepatocytes
    • 11929826 1:CAS:528:DC%2BD38XivVylurk%3D
    • Monga SP, Mars WM, Pediaditakis P, Bell A, Mule K, Bowen WC, Wang X, Zarnegar R, Michalopoulos GK (2002) Hepatocyte growth factor induces Wnt-independent nuclear translocation of beta-catenin after Met-beta-catenin dissociation in hepatocytes. Cancer Res 62(7):2064-2071
    • (2002) Cancer Res , vol.62 , Issue.7 , pp. 2064-2071
    • Monga, S.P.1    Mars, W.M.2    Pediaditakis, P.3    Bell, A.4    Mule, K.5    Bowen, W.C.6    Wang, X.7    Zarnegar, R.8    Michalopoulos, G.K.9
  • 147
    • 76649105065 scopus 로고    scopus 로고
    • Beta-catenin blocks Kras-dependent reprogramming of acini into pancreatic cancer precursor lesions in mice
    • Morris JPt, Cano DA, Sekine S, Wang SC, Hebrok M (2010) Beta-catenin blocks Kras-dependent reprogramming of acini into pancreatic cancer precursor lesions in mice. J Clin Invest 120(2):508-520
    • (2010) J Clin Invest , vol.120 , Issue.2 , pp. 508-520
    • Jpt, M.1    Cano, D.A.2    Sekine, S.3    Wang, S.C.4    Hebrok, M.5
  • 148
    • 1542346154 scopus 로고    scopus 로고
    • Wnt signalling via the epidermal growth factor receptor: A role in breast cancer?
    • 14979908 1:CAS:528:DC%2BD2cXotVSltb4%3D 10.1186/bcr737
    • Musgrove EA (2004) Wnt signalling via the epidermal growth factor receptor: a role in breast cancer? Breast Cancer Res 6(2):65-68
    • (2004) Breast Cancer Res , vol.6 , Issue.2 , pp. 65-68
    • Musgrove, E.A.1
  • 149
    • 0027512538 scopus 로고
    • Glycogen synthase kinase 3 phosphorylates Jun family members in vitro and negatively regulates their transactivating potential in intact cells
    • 8384354 1:CAS:528:DyaK3sXisV2itbc%3D
    • Nikolakaki E, Coffer PJ, Hemelsoet R, Woodgett JR, Defize LH (1993) Glycogen synthase kinase 3 phosphorylates Jun family members in vitro and negatively regulates their transactivating potential in intact cells. Oncogene 8(4):833-840
    • (1993) Oncogene , vol.8 , Issue.4 , pp. 833-840
    • Nikolakaki, E.1    Coffer, P.J.2    Hemelsoet, R.3    Woodgett, J.R.4    Defize, L.H.5
  • 152
    • 80053895720 scopus 로고    scopus 로고
    • Active ERK1/2 protein interacts with the phosphorylated nuclear constitutive active/androstane receptor (CAR; NR1I3), repressing dephosphorylation and sequestering CAR in the cytoplasm
    • 21873423 1:CAS:528:DC%2BC3MXht1yhtrnN 10.1074/jbc.M111.284596
    • Osabe M, Negishi M (2011) Active ERK1/2 protein interacts with the phosphorylated nuclear constitutive active/androstane receptor (CAR; NR1I3), repressing dephosphorylation and sequestering CAR in the cytoplasm. J Biol Chem 286(41):35763-35769
    • (2011) J Biol Chem , vol.286 , Issue.41 , pp. 35763-35769
    • Osabe, M.1    Negishi, M.2
  • 153
    • 78650674708 scopus 로고    scopus 로고
    • Rac GTPases in human diseases
    • 21178276 1:CAS:528:DC%2BC3cXhsFylt7fP
    • Pai SY, Kim C, Williams DA (2010) Rac GTPases in human diseases. Dis Markers 29(3-4):177-187
    • (2010) Dis Markers , vol.29 , Issue.3-4 , pp. 177-187
    • Pai, S.Y.1    Kim, C.2    Williams, D.A.3
  • 154
    • 77956938047 scopus 로고    scopus 로고
    • Beta-catenin signaling involves HGF-enhanced HepG2 scattering through activating MMP-7 transcription
    • 20677010 1:CAS:528:DC%2BC3cXhtVKhtL3J 10.1007/s00418-010-0729-3
    • Pan FY, Zhang SZ, Xu N, Meng FL, Zhang HX, Xue B, Han X, Li CJ (2010) Beta-catenin signaling involves HGF-enhanced HepG2 scattering through activating MMP-7 transcription. Histochem Cell Biol 134(3):285-295
    • (2010) Histochem Cell Biol , vol.134 , Issue.3 , pp. 285-295
    • Pan, F.Y.1    Zhang, S.Z.2    Xu, N.3    Meng, F.L.4    Zhang, H.X.5    Xue, B.6    Han, X.7    Li, C.J.8
  • 155
    • 0032577899 scopus 로고    scopus 로고
    • WNT-1 and HGF regulate GSK3 beta activity and beta-catenin signaling in mammary epithelial cells
    • 9647782 1:CAS:528:DyaK1cXkt12hsLw%3D 10.1006/bbrc.1998.8888
    • Papkoff J, Aikawa M (1998) WNT-1 and HGF regulate GSK3 beta activity and beta-catenin signaling in mammary epithelial cells. Biochem Biophys Res Commun 247(3):851-858
    • (1998) Biochem Biophys Res Commun , vol.247 , Issue.3 , pp. 851-858
    • Papkoff, J.1    Aikawa, M.2
  • 158
    • 0034997845 scopus 로고    scopus 로고
    • Mitogen-activated protein (MAP) kinase pathways: Regulation and physiological functions
    • 11294822 1:CAS:528:DC%2BD3MXjsFSntL4%3D 10.1210/er.22.2.153
    • Pearson G, Robinson F, Beers Gibson T, Xu BE, Karandikar M, Berman K, Cobb MH (2001) Mitogen-activated protein (MAP) kinase pathways: regulation and physiological functions. Endocr Rev 22(2):153-183
    • (2001) Endocr Rev , vol.22 , Issue.2 , pp. 153-183
    • Pearson, G.1    Robinson, F.2    Beers Gibson, T.3    Xu, B.E.4    Karandikar, M.5    Berman, K.6    Cobb, M.H.7
  • 159
    • 58249105729 scopus 로고    scopus 로고
    • K-ras and Wnt signaling synergize to accelerate prostate tumorigenesis in the mouse
    • 19117991 1:CAS:528:DC%2BD1MXmvFOk 10.1158/0008-5472.CAN-08-2895
    • Pearson HB, Phesse TJ, Clarke AR (2009) K-ras and Wnt signaling synergize to accelerate prostate tumorigenesis in the mouse. Cancer Res 69(1):94-101
    • (2009) Cancer Res , vol.69 , Issue.1 , pp. 94-101
    • Pearson, H.B.1    Phesse, T.J.2    Clarke, A.R.3
  • 162
    • 0034710915 scopus 로고    scopus 로고
    • Insulin-like growth factor 1 regulates the location, stability, and transcriptional activity of beta-catenin
    • 11035789 1:CAS:528:DC%2BD3cXnvVSgtLo%3D 10.1073/pnas.210394297
    • Playford MP, Bicknell D, Bodmer WF, Macaulay VM (2000) Insulin-like growth factor 1 regulates the location, stability, and transcriptional activity of beta-catenin. Proc Natl Acad Sci USA 97(22):12103-12108
    • (2000) Proc Natl Acad Sci USA , vol.97 , Issue.22 , pp. 12103-12108
    • Playford, M.P.1    Bicknell, D.2    Bodmer, W.F.3    MacAulay, V.M.4
  • 163
    • 0033895709 scopus 로고    scopus 로고
    • Wnt signaling and cancer
    • 10921899 1:CAS:528:DC%2BD3cXls1yqsbc%3D
    • Polakis P (2000) Wnt signaling and cancer. Genes Dev 14(15):1837-1851
    • (2000) Genes Dev , vol.14 , Issue.15 , pp. 1837-1851
    • Polakis, P.1
  • 164
    • 77951989203 scopus 로고    scopus 로고
    • The cancer/testis antigen CAGE with oncogenic potential stimulates cell proliferation by up-regulating cyclins D1 and e in an AP-1- and E2F-dependent manner
    • 20220142 1:CAS:528:DC%2BC3cXlsVOhsrc%3D 10.1074/jbc.M109.084400
    • Por E, Byun HJ, Lee EJ, Lim JH, Jung SY, Park I, Kim YM, Jeoung DI, Lee H (2010) The cancer/testis antigen CAGE with oncogenic potential stimulates cell proliferation by up-regulating cyclins D1 and E in an AP-1- and E2F-dependent manner. J Biol Chem 285(19):14475-14485
    • (2010) J Biol Chem , vol.285 , Issue.19 , pp. 14475-14485
    • Por, E.1    Byun, H.J.2    Lee, E.J.3    Lim, J.H.4    Jung, S.Y.5    Park, I.6    Kim, Y.M.7    Jeoung, D.I.8    Lee, H.9
  • 165
    • 0026648792 scopus 로고
    • Dioxin induces expression of c-fos and c-jun proto-oncogenes and a large increase in transcription factor AP-1
    • 1605850 1:CAS:528:DyaK38Xkt1Wkt7c%3D 10.1089/dna.1992.11.269
    • Puga A, Nebert DW, Carrier F (1992) Dioxin induces expression of c-fos and c-jun proto-oncogenes and a large increase in transcription factor AP-1. DNA Cell Biol 11(4):269-281
    • (1992) DNA Cell Biol , vol.11 , Issue.4 , pp. 269-281
    • Puga, A.1    Nebert, D.W.2    Carrier, F.3
  • 167
    • 33644864094 scopus 로고    scopus 로고
    • Involvement of Src family kinases in N-cadherin phosphorylation and beta-catenin dissociation during transendothelial migration of melanoma cells
    • 16371504 1:CAS:528:DC%2BD28XltlSqtLk%3D 10.1091/mbc.E05-10-0927
    • Qi J, Wang J, Romanyuk O, Siu CH (2006) Involvement of Src family kinases in N-cadherin phosphorylation and beta-catenin dissociation during transendothelial migration of melanoma cells. Mol Biol Cell 17(3):1261-1272
    • (2006) Mol Biol Cell , vol.17 , Issue.3 , pp. 1261-1272
    • Qi, J.1    Wang, J.2    Romanyuk, O.3    Siu, C.H.4
  • 168
    • 33847014441 scopus 로고    scopus 로고
    • A positive feedback loop between hepatocyte growth factor receptor and beta-catenin sustains colorectal cancer cell invasive growth
    • 16953230 1:CAS:528:DC%2BD2sXhslWhtLk%3D 10.1038/sj.onc.1209859
    • Rasola A, Fassetta M, De Bacco F, D'Alessandro L, Gramaglia D, Di Renzo MF, Comoglio PM (2007) A positive feedback loop between hepatocyte growth factor receptor and beta-catenin sustains colorectal cancer cell invasive growth. Oncogene 26(7):1078-1087
    • (2007) Oncogene , vol.26 , Issue.7 , pp. 1078-1087
    • Rasola, A.1    Fassetta, M.2    De Bacco, F.3    D'Alessandro, L.4    Gramaglia, D.5    Di Renzo, M.F.6    Comoglio, P.M.7
  • 169
    • 0030754559 scopus 로고    scopus 로고
    • Downregulation of aryl hydrocarbon receptor function and cytochrome P450 1A1 induction by expression of Ha-ras oncogenes
    • 9210956 1:CAS:528:DyaK2sXkt1ekuro%3D 10.1002/(SICI)1098-2744(199707)19: 2<91: AID-MC4>3.0.CO;2-O
    • Reiners JJ Jr, Jones CL, Hong N, Clift RE, Elferink C (1997) Downregulation of aryl hydrocarbon receptor function and cytochrome P450 1A1 induction by expression of Ha-ras oncogenes. Mol Carcinog 19(2):91-100
    • (1997) Mol Carcinog , vol.19 , Issue.2 , pp. 91-100
    • Reiners, Jr.J.J.1    Jones, C.L.2    Hong, N.3    Clift, R.E.4    Elferink, C.5
  • 170
    • 0034284027 scopus 로고    scopus 로고
    • Targeting the Ras signaling pathway: A rational, mechanism-based treatment for hematologic malignancies?
    • 10961860 1:CAS:528:DC%2BD3cXmt1Omt7g%3D
    • Reuter CW, Morgan MA, Bergmann L (2000) Targeting the Ras signaling pathway: a rational, mechanism-based treatment for hematologic malignancies? Blood 96(5):1655-1669
    • (2000) Blood , vol.96 , Issue.5 , pp. 1655-1669
    • Reuter, C.W.1    Morgan, M.A.2    Bergmann, L.3
  • 171
    • 17244376814 scopus 로고    scopus 로고
    • Wnt signalling in stem cells and cancer
    • 15829953 1:CAS:528:DC%2BD2MXjtFOmsrw%3D 10.1038/nature03319
    • Reya T, Clevers H (2005) Wnt signalling in stem cells and cancer. Nature 434(7035):843-850
    • (2005) Nature , vol.434 , Issue.7035 , pp. 843-850
    • Reya, T.1    Clevers, H.2
  • 173
    • 1642351837 scopus 로고    scopus 로고
    • A Raf/MEK/ERK signaling pathway is required for development of the sea urchin embryo micromere lineage through phosphorylation of the transcription factor Ets
    • 14973284 10.1242/dev.01000 1:CAS:528:DC%2BD2cXis1emsr0%3D
    • Rottinger E, Besnardeau L, Lepage T (2004) A Raf/MEK/ERK signaling pathway is required for development of the sea urchin embryo micromere lineage through phosphorylation of the transcription factor Ets. Development 131(5):1075-1087
    • (2004) Development , vol.131 , Issue.5 , pp. 1075-1087
    • Rottinger, E.1    Besnardeau, L.2    Lepage, T.3
  • 174
    • 0033579480 scopus 로고    scopus 로고
    • Regulation of E-cadherin/Catenin association by tyrosine phosphorylation
    • 10593980 1:CAS:528:DC%2BD3cXit1Cq 10.1074/jbc.274.51.36734
    • Roura S, Miravet S, Piedra J, Garcia de Herreros A, Dunach M (1999) Regulation of E-cadherin/Catenin association by tyrosine phosphorylation. J Biol Chem 274(51):36734-36740
    • (1999) J Biol Chem , vol.274 , Issue.51 , pp. 36734-36740
    • Roura, S.1    Miravet, S.2    Piedra, J.3    Garcia De Herreros, A.4    Dunach, M.5
  • 175
    • 0141816802 scopus 로고    scopus 로고
    • Dissecting the roles of beta-catenin and cyclin D1 during mammary development and neoplasia
    • 13679587 1:CAS:528:DC%2BD3sXotFKmsL4%3D 10.1073/pnas.1534601100
    • Rowlands TM, Pechenkina IV, Hatsell SJ, Pestell RG, Cowin P (2003) Dissecting the roles of beta-catenin and cyclin D1 during mammary development and neoplasia. Proc Natl Acad Sci USA 100(20):11400-11405
    • (2003) Proc Natl Acad Sci USA , vol.100 , Issue.20 , pp. 11400-11405
    • Rowlands, T.M.1    Pechenkina, I.V.2    Hatsell, S.J.3    Pestell, R.G.4    Cowin, P.5
  • 176
    • 3843113598 scopus 로고    scopus 로고
    • Beta-catenin and cyclin D1: Connecting development to breast cancer
    • 14712077 1:CAS:528:DC%2BD2cXisFGnu7c%3D 10.4161/cc.3.2.665
    • Rowlands TM, Pechenkina IV, Hatsell S, Cowin P (2004) Beta-catenin and cyclin D1: connecting development to breast cancer. Cell Cycle 3(2):145-148
    • (2004) Cell Cycle , vol.3 , Issue.2 , pp. 145-148
    • Rowlands, T.M.1    Pechenkina, I.V.2    Hatsell, S.3    Cowin, P.4
  • 177
    • 57149103697 scopus 로고    scopus 로고
    • Transcription factor Egr1 acts as an upstream regulator of beta-catenin signalling through up-regulation of TCF4 and p300 expression during trans-differentiation of endometrial carcinoma cells
    • 18798221 1:CAS:528:DC%2BD1MXlvVWqtg%3D%3D 10.1002/path.2404
    • Saegusa M, Hashimura M, Kuwata T, Hamano M, Watanabe J, Kawaguchi M, Okayasu I (2008) Transcription factor Egr1 acts as an upstream regulator of beta-catenin signalling through up-regulation of TCF4 and p300 expression during trans-differentiation of endometrial carcinoma cells. J Pathol 216(4):521-532
    • (2008) J Pathol , vol.216 , Issue.4 , pp. 521-532
    • Saegusa, M.1    Hashimura, M.2    Kuwata, T.3    Hamano, M.4    Watanabe, J.5    Kawaguchi, M.6    Okayasu, I.7
  • 179
    • 0031561127 scopus 로고    scopus 로고
    • Increased MAPK expression and activity in primary human hepatocellular carcinoma
    • 9223425 1:CAS:528:DyaK2sXksFOhurk%3D 10.1006/bbrc.1997.6840
    • Schmidt CM, McKillop IH, Cahill PA, Sitzmann JV (1997) Increased MAPK expression and activity in primary human hepatocellular carcinoma. Biochem Biophys Res Commun 236(1):54-58
    • (1997) Biochem Biophys Res Commun , vol.236 , Issue.1 , pp. 54-58
    • Schmidt, C.M.1    McKillop, I.H.2    Cahill, P.A.3    Sitzmann, J.V.4
  • 181
    • 33845373278 scopus 로고    scopus 로고
    • Colorectal cancer and genetic alterations in the Wnt pathway
    • 17143297 1:CAS:528:DC%2BD28Xht1Kgt7%2FK 10.1038/sj.onc.1210059
    • Segditsas S, Tomlinson I (2006) Colorectal cancer and genetic alterations in the Wnt pathway. Oncogene 25(57):7531-7537
    • (2006) Oncogene , vol.25 , Issue.57 , pp. 7531-7537
    • Segditsas, S.1    Tomlinson, I.2
  • 182
    • 0029011218 scopus 로고
    • The MAPK signaling cascade
    • 7601337 1:CAS:528:DyaK2MXmvFCltb0%3D
    • Seger R, Krebs EG (1995) The MAPK signaling cascade. FASEB J 9(9):726-735
    • (1995) FASEB J , vol.9 , Issue.9 , pp. 726-735
    • Seger, R.1    Krebs, E.G.2
  • 183
    • 33847749416 scopus 로고    scopus 로고
    • Liver-specific loss of beta-catenin results in delayed hepatocyte proliferation after partial hepatectomy
    • 17256747 1:CAS:528:DC%2BD2sXisVKgu7c%3D 10.1002/hep.21523
    • Sekine S, Gutierrez PJ, Lan BY, Feng S, Hebrok M (2007) Liver-specific loss of beta-catenin results in delayed hepatocyte proliferation after partial hepatectomy. Hepatology 45(2):361-368
    • (2007) Hepatology , vol.45 , Issue.2 , pp. 361-368
    • Sekine, S.1    Gutierrez, P.J.2    Lan, B.Y.3    Feng, S.4    Hebrok, M.5
  • 184
    • 0030944985 scopus 로고    scopus 로고
    • Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a
    • 9054499 1:CAS:528:DyaK2sXhvVSit7k%3D 10.1016/S0092-8674(00)81902-9
    • Serrano M, Lin AW, McCurrach ME, Beach D, Lowe SW (1997) Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a. Cell 88(5):593-602
    • (1997) Cell , vol.88 , Issue.5 , pp. 593-602
    • Serrano, M.1    Lin, A.W.2    McCurrach, M.E.3    Beach, D.4    Lowe, S.W.5
  • 185
    • 5044221069 scopus 로고    scopus 로고
    • Mutation of beta-catenin does not coexist with K-ras mutation in colorectal tumorigenesis
    • 15573917 1:CAS:528:DC%2BD2cXnvFGrsbg%3D 10.1023/B:DDAS.0000043376.41820. a6
    • Shitoh K, Koinuma K, Furukawa T, Okada M, Nagai H (2004) Mutation of beta-catenin does not coexist with K-ras mutation in colorectal tumorigenesis. Dig Dis Sci 49(10):1631-1633
    • (2004) Dig Dis Sci , vol.49 , Issue.10 , pp. 1631-1633
    • Shitoh, K.1    Koinuma, K.2    Furukawa, T.3    Okada, M.4    Nagai, H.5
  • 187
    • 0034604726 scopus 로고    scopus 로고
    • Endogenous protein kinase CK2 participates in Wnt signaling in mammary epithelial cells
    • 10806215 1:CAS:528:DC%2BD3cXls12mu70%3D 10.1074/jbc.M909107199
    • Song DH, Sussman DJ, Seldin DC (2000) Endogenous protein kinase CK2 participates in Wnt signaling in mammary epithelial cells. J Biol Chem 275(31):23790-23797
    • (2000) J Biol Chem , vol.275 , Issue.31 , pp. 23790-23797
    • Song, D.H.1    Sussman, D.J.2    Seldin, D.C.3
  • 188
    • 0038267245 scopus 로고    scopus 로고
    • CK2 phosphorylation of the armadillo repeat region of beta-catenin potentiates Wnt signaling
    • 12700239 1:CAS:528:DC%2BD3sXkslynsrw%3D 10.1074/jbc.M212260200
    • Song DH, Dominguez I, Mizuno J, Kaut M, Mohr SC, Seldin DC (2003) CK2 phosphorylation of the armadillo repeat region of beta-catenin potentiates Wnt signaling. J Biol Chem 278(26):24018-24025
    • (2003) J Biol Chem , vol.278 , Issue.26 , pp. 24018-24025
    • Song, D.H.1    Dominguez, I.2    Mizuno, J.3    Kaut, M.4    Mohr, S.C.5    Seldin, D.C.6
  • 190
    • 0027960448 scopus 로고
    • Mitogen inactivation of glycogen synthase kinase-3 beta in intact cells via serine 9 phosphorylation
    • 7980435 1:CAS:528:DyaK2cXmsFaitLs%3D
    • Stambolic V, Woodgett JR (1994) Mitogen inactivation of glycogen synthase kinase-3 beta in intact cells via serine 9 phosphorylation. Biochem J 303(Pt 3):701-704
    • (1994) Biochem J , vol.303 , Issue.PART 3 , pp. 701-704
    • Stambolic, V.1    Woodgett, J.R.2
  • 191
    • 33747877570 scopus 로고    scopus 로고
    • PCB 153, a non-dioxin-like Tumor Promoter, Selects for {beta}-Catenin (Catnb) Mutated Mouse Liver Tumors
    • 16782779 1:CAS:528:DC%2BD28Xotl2ksLo%3D 10.1093/toxsci/kfl041
    • Strathmann J, Schwarz M, Tharappel JC, Glauert HP, Spear BT, Robertson LW, Appel KE, Buchmann A (2006) PCB 153, a non-dioxin-like Tumor Promoter, Selects for {beta}-Catenin (Catnb) Mutated Mouse Liver Tumors. Toxicol Sci 93(1):34-40
    • (2006) Toxicol Sci , vol.93 , Issue.1 , pp. 34-40
    • Strathmann, J.1    Schwarz, M.2    Tharappel, J.C.3    Glauert, H.P.4    Spear, B.T.5    Robertson, L.W.6    Appel, K.E.7    Buchmann, A.8
  • 192
    • 0036607704 scopus 로고    scopus 로고
    • Aryl hydrocarbon receptor-dependent inhibition of AP-1 activity by 2,3,7,8-tetrachlorodibenzo-p-dioxin in activated B cells
    • 12051995 1:CAS:528:DC%2BD38XktlWqtbg%3D 10.1006/taap.2002.9403
    • Suh J, Jeon YJ, Kim HM, Kang JS, Kaminski NE, Yang KH (2002) Aryl hydrocarbon receptor-dependent inhibition of AP-1 activity by 2,3,7,8-tetrachlorodibenzo-p-dioxin in activated B cells. Toxicol Appl Pharmacol 181(2):116-123
    • (2002) Toxicol Appl Pharmacol , vol.181 , Issue.2 , pp. 116-123
    • Suh, J.1    Jeon, Y.J.2    Kim, H.M.3    Kang, J.S.4    Kaminski, N.E.5    Yang, K.H.6
  • 194
    • 1542512457 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3beta is tyrosine-phosphorylated by MEK1 in human skin fibroblasts
    • 15020233 1:CAS:528:DC%2BD2cXitFKhtbk%3D 10.1016/j.bbrc.2004.02.061
    • Takahashi-Yanaga F, Shiraishi F, Hirata M, Miwa Y, Morimoto S, Sasaguri T (2004) Glycogen synthase kinase-3beta is tyrosine-phosphorylated by MEK1 in human skin fibroblasts. Biochem Biophys Res Commun 316(2):411-415
    • (2004) Biochem Biophys Res Commun , vol.316 , Issue.2 , pp. 411-415
    • Takahashi-Yanaga, F.1    Shiraishi, F.2    Hirata, M.3    Miwa, Y.4    Morimoto, S.5    Sasaguri, T.6
  • 197
    • 0033119801 scopus 로고    scopus 로고
    • Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells
    • 10201372 1:CAS:528:DyaK1MXisFGksrY%3D 10.1038/18884
    • Tetsu O, McCormick F (1999) Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells. Nature 398(6726):422-426
    • (1999) Nature , vol.398 , Issue.6726 , pp. 422-426
    • Tetsu, O.1    McCormick, F.2
  • 198
    • 0037155243 scopus 로고    scopus 로고
    • Activation of the Wnt pathway interferes with serum response element-driven transcription of immediate early genes
    • 11751871 1:CAS:528:DC%2BD38XhvFyrtb4%3D 10.1074/jbc.M111255200
    • Tice DA, Soloviev I, Polakis P (2002) Activation of the Wnt pathway interferes with serum response element-driven transcription of immediate early genes. J Biol Chem 277(8):6118-6123
    • (2002) J Biol Chem , vol.277 , Issue.8 , pp. 6118-6123
    • Tice, D.A.1    Soloviev, I.2    Polakis, P.3
  • 199
    • 79958827787 scopus 로고    scopus 로고
    • The transforming growth factor-alpha and cyclin D1 genes are direct targets of beta-catenin signaling in hepatocyte proliferation
    • 21145869 1:CAS:528:DC%2BC3MXnslehtLY%3D 10.1016/j.jhep.2010.10.021
    • Torre C, Benhamouche S, Mitchell C, Godard C, Veber P, Letourneur F, Cagnard N, Jacques S, Finzi L, Perret C, Colnot S (2011) The transforming growth factor-alpha and cyclin D1 genes are direct targets of beta-catenin signaling in hepatocyte proliferation. J Hepatol 55(1):86-95
    • (2011) J Hepatol , vol.55 , Issue.1 , pp. 86-95
    • Torre, C.1    Benhamouche, S.2    Mitchell, C.3    Godard, C.4    Veber, P.5    Letourneur, F.6    Cagnard, N.7    Jacques, S.8    Finzi, L.9    Perret, C.10    Colnot, S.11
  • 200
    • 34249336416 scopus 로고    scopus 로고
    • Physical and functional cooperation between AP-1 and beta-catenin for the regulation of TCF-dependent genes
    • 17146436 1:CAS:528:DC%2BD2sXls1Gqtrg%3D 10.1038/sj.onc.1210133
    • Toualbi K, Guller MC, Mauriz JL, Labalette C, Buendia MA, Mauviel A, Bernuau D (2007) Physical and functional cooperation between AP-1 and beta-catenin for the regulation of TCF-dependent genes. Oncogene 26(24):3492-3502
    • (2007) Oncogene , vol.26 , Issue.24 , pp. 3492-3502
    • Toualbi, K.1    Guller, M.C.2    Mauriz, J.L.3    Labalette, C.4    Buendia, M.A.5    Mauviel, A.6    Bernuau, D.7
  • 201
    • 84863712242 scopus 로고    scopus 로고
    • The transcription factor c-Jun protects against liver damage following activated beta-Catenin signaling
    • 22792392 1:CAS:528:DC%2BC38XhtVemsr%2FP 10.1371/journal.pone.0040638
    • Trierweiler C, Blum HE, Hasselblatt P (2012) The transcription factor c-Jun protects against liver damage following activated beta-Catenin signaling. PLoS ONE 7(7):e40638
    • (2012) PLoS ONE , vol.7 , Issue.7 , pp. 40638
    • Trierweiler, C.1    Blum, H.E.2    Hasselblatt, P.3
  • 204
    • 78751535289 scopus 로고    scopus 로고
    • AP-1 regulates cyclin D1 and c-MYC transcription in an AKT-dependent manner in response to mTOR inhibition: Role of AIP4/Itch-mediated JUNB degradation
    • 21135252 1:CAS:528:DC%2BC3MXmslGrtg%3D%3D 10.1158/1541-7786.MCR-10-0105
    • Vartanian R, Masri J, Martin J, Cloninger C, Holmes B, Artinian N, Funk A, Ruegg T, Gera J (2011) AP-1 regulates cyclin D1 and c-MYC transcription in an AKT-dependent manner in response to mTOR inhibition: role of AIP4/Itch-mediated JUNB degradation. Mol Cancer Res 9(1):115-130
    • (2011) Mol Cancer Res , vol.9 , Issue.1 , pp. 115-130
    • Vartanian, R.1    Masri, J.2    Martin, J.3    Cloninger, C.4    Holmes, B.5    Artinian, N.6    Funk, A.7    Ruegg, T.8    Gera, J.9
  • 205
    • 81555197046 scopus 로고    scopus 로고
    • ERK1/2 MAPKs and Wnt signaling pathways are independently involved in adipocytokine-mediated aldosterone secretion
    • 21915818 1:CAS:528:DC%2BC38XkvFGgsw%3D%3D 10.1055/s-0031-1284367
    • Vleugels K, Schinner S, Krause D, Morawietz H, Bornstein SR, Ehrhart-Bornstein M, Krug AW (2011) ERK1/2 MAPKs and Wnt signaling pathways are independently involved in adipocytokine-mediated aldosterone secretion. Exp Clin Endocrinol Diabetes 119(10):644-648
    • (2011) Exp Clin Endocrinol Diabetes , vol.119 , Issue.10 , pp. 644-648
    • Vleugels, K.1    Schinner, S.2    Krause, D.3    Morawietz, H.4    Bornstein, S.R.5    Ehrhart-Bornstein, M.6    Krug, A.W.7
  • 206
    • 78149337402 scopus 로고    scopus 로고
    • Canonical Wnt/beta-catenin regulation of liver receptor homolog-1 mediates pluripotency gene expression
    • 20734354 1:CAS:528:DC%2BC3cXhsFKntb3E 10.1002/stem.502
    • Wagner RT, Xu X, Yi F, Merrill BJ, Cooney AJ (2010) Canonical Wnt/beta-catenin regulation of liver receptor homolog-1 mediates pluripotency gene expression. Stem Cells 28(10):1794-1804
    • (2010) Stem Cells , vol.28 , Issue.10 , pp. 1794-1804
    • Wagner, R.T.1    Xu, X.2    Yi, F.3    Merrill, B.J.4    Cooney, A.J.5
  • 207
    • 30044445850 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3 is a negative regulator of extracellular signal-regulated kinase
    • 16278684
    • Wang Q, Zhou Y, Wang X, Evers BM (2006) Glycogen synthase kinase-3 is a negative regulator of extracellular signal-regulated kinase. Oncogene 25(1):43-50
    • (2006) Oncogene , vol.25 , Issue.1 , pp. 43-50
    • Wang, Q.1    Zhou, Y.2    Wang, X.3    Evers, B.M.4
  • 208
    • 80052290466 scopus 로고    scopus 로고
    • Estrogen induces c-myc gene expression via an upstream enhancer activated by the estrogen receptor and the AP-1 transcription factor
    • 21835891 1:CAS:528:DC%2BC3MXht1ykt7zL 10.1210/me.2011-1037
    • Wang C, Mayer JA, Mazumdar A, Fertuck K, Kim H, Brown M, Brown PH (2011) Estrogen induces c-myc gene expression via an upstream enhancer activated by the estrogen receptor and the AP-1 transcription factor. Mol Endocrinol 25(9):1527-1538
    • (2011) Mol Endocrinol , vol.25 , Issue.9 , pp. 1527-1538
    • Wang, C.1    Mayer, J.A.2    Mazumdar, A.3    Fertuck, K.4    Kim, H.5    Brown, M.6    Brown, P.H.7
  • 209
    • 84868699233 scopus 로고    scopus 로고
    • Foxm1 mediates cross talk between Kras/mitogen-activated protein kinase and canonical Wnt pathways during development of respiratory epithelium
    • 22826436 1:CAS:528:DC%2BC38XhsVSltrzP 10.1128/MCB.00355-12
    • Wang IC, Snyder J, Zhang Y, Lander J, Nakafuku Y, Lin J, Chen G, Kalin TV, Whitsett JA, Kalinichenko VV (2012) Foxm1 mediates cross talk between Kras/mitogen-activated protein kinase and canonical Wnt pathways during development of respiratory epithelium. Mol Cell Biol 32(19):3838-3850
    • (2012) Mol Cell Biol , vol.32 , Issue.19 , pp. 3838-3850
    • Wang, I.C.1    Snyder, J.2    Zhang, Y.3    Lander, J.4    Nakafuku, Y.5    Lin, J.6    Chen, G.7    Kalin, T.V.8    Whitsett, J.A.9    Kalinichenko, V.V.10
  • 210
    • 22244476115 scopus 로고    scopus 로고
    • The v-Jun point mutation allows c-Jun to escape GSK3-dependent recognition and destruction by the Fbw7 ubiquitin ligase
    • 16023596 1:CAS:528:DC%2BD2MXntVejs70%3D 10.1016/j.ccr.2005.06.005
    • Wei W, Jin J, Schlisio S, Harper JW, Kaelin WG Jr (2005) The v-Jun point mutation allows c-Jun to escape GSK3-dependent recognition and destruction by the Fbw7 ubiquitin ligase. Cancer Cell 8(1):25-33
    • (2005) Cancer Cell , vol.8 , Issue.1 , pp. 25-33
    • Wei, W.1    Jin, J.2    Schlisio, S.3    Harper, J.W.4    Kaelin, Jr.W.G.5
  • 211
    • 0036240630 scopus 로고    scopus 로고
    • Cyclin D1 overexpression in colorectal carcinoma in vivo is dependent on beta-catenin protein dysregulation, but not k-ras mutation
    • 12081197 1:CAS:528:DC%2BD38Xkt1Sgtb0%3D 10.1002/path.1113
    • Wong NA, Morris RG, McCondochie A, Bader S, Jodrell DI, Harrison DJ (2002) Cyclin D1 overexpression in colorectal carcinoma in vivo is dependent on beta-catenin protein dysregulation, but not k-ras mutation. J Pathol 197(1):128-135
    • (2002) J Pathol , vol.197 , Issue.1 , pp. 128-135
    • Wong, N.A.1    Morris, R.G.2    McCondochie, A.3    Bader, S.4    Jodrell, D.I.5    Harrison, D.J.6
  • 212
    • 41949105179 scopus 로고    scopus 로고
    • Rac1 activation controls nuclear localization of beta-catenin during canonical Wnt signaling
    • 18423204 1:CAS:528:DC%2BD1cXltlWnu7Y%3D 10.1016/j.cell.2008.01.052
    • Wu X, Tu X, Joeng KS, Hilton MJ, Williams DA, Long F (2008) Rac1 activation controls nuclear localization of beta-catenin during canonical Wnt signaling. Cell 133(2):340-353
    • (2008) Cell , vol.133 , Issue.2 , pp. 340-353
    • Wu, X.1    Tu, X.2    Joeng, K.S.3    Hilton, M.J.4    Williams, D.A.5    Long, F.6
  • 213
    • 69249100142 scopus 로고    scopus 로고
    • Threonine 393 of beta-catenin regulates interaction with Axin
    • 19565571 1:CAS:528:DC%2BD1MXhtVGju7vI 10.1002/jcb.22260
    • Wu H, Symes K, Seldin DC, Dominguez I (2009) Threonine 393 of beta-catenin regulates interaction with Axin. J Cell Biochem 108(1):52-63
    • (2009) J Cell Biochem , vol.108 , Issue.1 , pp. 52-63
    • Wu, H.1    Symes, K.2    Seldin, D.C.3    Dominguez, I.4
  • 215
    • 27544467453 scopus 로고    scopus 로고
    • Bombesin regulates cyclin D1 expression through the early growth response protein Egr-1 in prostate cancer cells
    • 16267018 1:CAS:528:DC%2BD2MXhtFKktLjO 10.1158/0008-5472.CAN-05-1830
    • Xiao D, Chinnappan D, Pestell R, Albanese C, Weber HC (2005) Bombesin regulates cyclin D1 expression through the early growth response protein Egr-1 in prostate cancer cells. Cancer Res 65(21):9934-9942
    • (2005) Cancer Res , vol.65 , Issue.21 , pp. 9934-9942
    • Xiao, D.1    Chinnappan, D.2    Pestell, R.3    Albanese, C.4    Weber, H.C.5
  • 216
    • 0346244032 scopus 로고    scopus 로고
    • Increased cyclin D1 expression in cancer of the ampulla of Vater: Relevance to nuclear beta catenin accumulation and k-ras gene mutation
    • 14645696 1:CAS:528:DC%2BD2cXktlKisA%3D%3D 10.1136/mp.56.6.336
    • Yamazaki K, Hanami K, Nagao T, Asoh A, Sugano I, Ishida Y (2003) Increased cyclin D1 expression in cancer of the ampulla of Vater: relevance to nuclear beta catenin accumulation and k-ras gene mutation. Mol Pathol 56(6):336-341
    • (2003) Mol Pathol , vol.56 , Issue.6 , pp. 336-341
    • Yamazaki, K.1    Hanami, K.2    Nagao, T.3    Asoh, A.4    Sugano, I.5    Ishida, Y.6
  • 217
    • 82555170271 scopus 로고    scopus 로고
    • Nuclear PKM2 regulates beta-catenin transactivation upon EGFR activation
    • 22056988 1:CAS:528:DC%2BC3MXhsVagtbvP 10.1038/nature10598
    • Yang W, Xia Y, Ji H, Zheng Y, Liang J, Huang W, Gao X, Aldape K, Lu Z (2011) Nuclear PKM2 regulates beta-catenin transactivation upon EGFR activation. Nature 480(7375):118-122
    • (2011) Nature , vol.480 , Issue.7375 , pp. 118-122
    • Yang, W.1    Xia, Y.2    Ji, H.3    Zheng, Y.4    Liang, J.5    Huang, W.6    Gao, X.7    Aldape, K.8    Lu, Z.9
  • 219
    • 77954112841 scopus 로고    scopus 로고
    • Epigenetic disruption of the WNT/beta-catenin signaling pathway in human cancers
    • 19633433 1:CAS:528:DC%2BC3cXitVWhtrg%3D 10.4161/epi.4.5.9371
    • Ying Y, Tao Q (2009) Epigenetic disruption of the WNT/beta-catenin signaling pathway in human cancers. Epigenetics 4(5):307-312
    • (2009) Epigenetics , vol.4 , Issue.5 , pp. 307-312
    • Ying, Y.1    Tao, Q.2
  • 220
    • 79955415754 scopus 로고    scopus 로고
    • Multiple Wnt/ss-catenin responsive enhancers align with the MYC promoter through long-range chromatin loops
    • 21533051 1:CAS:528:DC%2BC3MXltlGqtbs%3D 10.1371/journal.pone.0018966
    • Yochum GS (2011) Multiple Wnt/ss-catenin responsive enhancers align with the MYC promoter through long-range chromatin loops. PLoS ONE 6(4):e18966
    • (2011) PLoS ONE , vol.6 , Issue.4 , pp. 18966
    • Yochum, G.S.1
  • 221
    • 76249105057 scopus 로고    scopus 로고
    • A beta-catenin/TCF-coordinated chromatin loop at MYC integrates 5′ and 3′ Wnt responsive enhancers
    • 19966299 1:CAS:528:DC%2BC3cXnsFCmsg%3D%3D 10.1073/pnas.0912294107
    • Yochum GS, Sherrick CM, Macpartlin M, Goodman RH (2010) A beta-catenin/TCF-coordinated chromatin loop at MYC integrates 5′ and 3′ Wnt responsive enhancers. Proc Natl Acad Sci USA 107(1):145-150
    • (2010) Proc Natl Acad Sci USA , vol.107 , Issue.1 , pp. 145-150
    • Yochum, G.S.1    Sherrick, C.M.2    MacPartlin, M.3    Goodman, R.H.4
  • 222
    • 29244436111 scopus 로고    scopus 로고
    • Ras regulates neuronal polarity via the PI3-kinase/Akt/GSK-3beta/CRMP-2 pathway
    • 16343426 1:CAS:528:DC%2BD2MXhtlCqur7J 10.1016/j.bbrc.2005.11.147
    • Yoshimura T, Arimura N, Kawano Y, Kawabata S, Wang S, Kaibuchi K (2006) Ras regulates neuronal polarity via the PI3-kinase/Akt/GSK-3beta/CRMP-2 pathway. Biochem Biophys Res Commun 340(1):62-68
    • (2006) Biochem Biophys Res Commun , vol.340 , Issue.1 , pp. 62-68
    • Yoshimura, T.1    Arimura, N.2    Kawano, Y.3    Kawabata, S.4    Wang, S.5    Kaibuchi, K.6
  • 223
    • 84856007344 scopus 로고    scopus 로고
    • Structural basis of coactivation of liver receptor homolog-1 by beta-catenin
    • 22187462 1:CAS:528:DC%2BC38XhsVehsLk%3D 10.1073/pnas.1117036108
    • Yumoto F, Nguyen P, Sablin EP, Baxter JD, Webb P, Fletterick RJ (2012) Structural basis of coactivation of liver receptor homolog-1 by beta-catenin. Proc Natl Acad Sci USA 109(1):143-148
    • (2012) Proc Natl Acad Sci USA , vol.109 , Issue.1 , pp. 143-148
    • Yumoto, F.1    Nguyen, P.2    Sablin, E.P.3    Baxter, J.D.4    Webb, P.5    Fletterick, R.J.6
  • 224
    • 14044252936 scopus 로고    scopus 로고
    • Both ERK and Wnt/beta-catenin pathways are involved in Wnt3a-induced proliferation
    • 15615777 1:CAS:528:DC%2BD2MXhslymur8%3D 10.1242/jcs.01601
    • Yun MS, Kim SE, Jeon SH, Lee JS, Choi KY (2005) Both ERK and Wnt/beta-catenin pathways are involved in Wnt3a-induced proliferation. J Cell Sci 118(Pt 2):313-322
    • (2005) J Cell Sci , vol.118 , Issue.PART 2 , pp. 313-322
    • Yun, M.S.1    Kim, S.E.2    Jeon, S.H.3    Lee, J.S.4    Choi, K.Y.5
  • 225
    • 84869480383 scopus 로고    scopus 로고
    • Dual-specificity phosphatases are targets of the Wnt/β-catenin pathway and candidate mediators of β-catenin/Ras signaling interactions
    • 23089536 1:CAS:528:DC%2BC38Xhs1ahsrjI 10.1515/hsz-2012-0130
    • Zeller E, Mock K, Horn M, Colnot S, Schwarz M, Braeuning A (2012) Dual-specificity phosphatases are targets of the Wnt/β-catenin pathway and candidate mediators of β-catenin/Ras signaling interactions. Biol Chem 393(10):1183-1191
    • (2012) Biol Chem , vol.393 , Issue.10 , pp. 1183-1191
    • Zeller, E.1    Mock, K.2    Horn, M.3    Colnot, S.4    Schwarz, M.5    Braeuning, A.6
  • 226
    • 33749117134 scopus 로고    scopus 로고
    • Tyrosine residues 654 and 670 in beta-catenin are crucial in regulation of Met-beta-catenin interactions
    • 16952352 1:CAS:528:DC%2BD28XhtVGisLvN 10.1016/j.yexcr.2006.08.003
    • Zeng G, Apte U, Micsenyi A, Bell A, Monga SP (2006) Tyrosine residues 654 and 670 in beta-catenin are crucial in regulation of Met-beta-catenin interactions. Exp Cell Res 312(18):3620-3630
    • (2006) Exp Cell Res , vol.312 , Issue.18 , pp. 3620-3630
    • Zeng, G.1    Apte, U.2    Micsenyi, A.3    Bell, A.4    Monga, S.P.5
  • 227
    • 0035893568 scopus 로고    scopus 로고
    • Evidence that APC regulates survivin expression: A possible mechanism contributing to the stem cell origin of colon cancer
    • 11751382 1:CAS:528:DC%2BD38Xht1OgsQ%3D%3D
    • Zhang T, Otevrel T, Gao Z, Gao Z, Ehrlich SM, Fields JZ, Boman BM (2001) Evidence that APC regulates survivin expression: a possible mechanism contributing to the stem cell origin of colon cancer. Cancer Res 61(24):8664-8667
    • (2001) Cancer Res , vol.61 , Issue.24 , pp. 8664-8667
    • Zhang, T.1    Otevrel, T.2    Gao, Z.3    Gao, Z.4    Ehrlich, S.M.5    Fields, J.Z.6    Boman, B.M.7
  • 228
    • 77950877457 scopus 로고    scopus 로고
    • Dual specificity phosphatase 6 (DUSP6) is an ETS-regulated negative feedback mediator of oncogenic ERK signaling in lung cancer cells
    • 20097731 10.1093/carcin/bgq020 1:CAS:528:DC%2BC3cXkt1OlsLo%3D
    • Zhang Z, Kobayashi S, Borczuk AC, Leidner RS, Laframboise T, Levine AD, Halmos B (2010) Dual specificity phosphatase 6 (DUSP6) is an ETS-regulated negative feedback mediator of oncogenic ERK signaling in lung cancer cells. Carcinogenesis 31(4):577-586
    • (2010) Carcinogenesis , vol.31 , Issue.4 , pp. 577-586
    • Zhang, Z.1    Kobayashi, S.2    Borczuk, A.C.3    Leidner, R.S.4    Laframboise, T.5    Levine, A.D.6    Halmos, B.7
  • 229
    • 80052052253 scopus 로고    scopus 로고
    • Mutant K-Ras increases GSK-3beta gene expression via an ETS-p300 transcriptional complex in pancreatic cancer
    • 21441955 1:CAS:528:DC%2BC3MXjvVOisb0%3D 10.1038/onc.2011.90
    • Zhang JS, Koenig A, Harrison A, Ugolkov AV, Fernandez-Zapico ME, Couch FJ, Billadeau DD (2011a) Mutant K-Ras increases GSK-3beta gene expression via an ETS-p300 transcriptional complex in pancreatic cancer. Oncogene 30(34):3705-3715
    • (2011) Oncogene , vol.30 , Issue.34 , pp. 3705-3715
    • Zhang, J.S.1    Koenig, A.2    Harrison, A.3    Ugolkov, A.V.4    Fernandez-Zapico, M.E.5    Couch, F.J.6    Billadeau, D.D.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.