-
1
-
-
67651003108
-
Computational identification of a p38SAPK-regulated transcription factor network required for tumor cell quiescence
-
Adam AP, George A, Schewe D, Bragado P, Iglesias BV, Ranganathan AC et al (2009). Computational identification of a p38SAPK-regulated transcription factor network required for tumor cell quiescence. Cancer Res 69: 5664-5672.
-
(2009)
Cancer Res
, vol.69
, pp. 5664-5672
-
-
Adam, A.P.1
George, A.2
Schewe, D.3
Bragado, P.4
Iglesias, B.V.5
Ranganathan, A.C.6
-
2
-
-
12344260906
-
The p38 SAPK pathway is required for Ha-ras induced in vitro invasion of NIH3T3 cells
-
Behren A, Binder K, Vucelic G, Herberhold S, Hirt B, Loewenheim H et al (2005). The p38 SAPK pathway is required for Ha-ras induced in vitro invasion of NIH3T3 cells. Exp Cell Res 303: 321-330.
-
(2005)
Exp Cell Res
, vol.303
, pp. 321-330
-
-
Behren, A.1
Binder, K.2
Vucelic, G.3
Herberhold, S.4
Hirt, B.5
Loewenheim, H.6
-
3
-
-
3042961052
-
Experimental metastasis in nude mice of NIH 3T3 cells containing various ras genes
-
Bradley MO, Kraynak AR, Storer RD, Gibbs JB. (1986). Experimental metastasis in nude mice of NIH 3T3 cells containing various ras genes. Proc Natl Acad Sci USA 83: 5277-5281.
-
(1986)
Proc Natl Acad Sci USA
, vol.83
, pp. 5277-5281
-
-
Bradley, M.O.1
Kraynak, A.R.2
Storer, R.D.3
Gibbs, J.B.4
-
4
-
-
34248152719
-
MAP-ing glioma invasion: Mitogen-activated protein kinase kinase 3 and p38 drive glioma invasion and progression and predict patient survival
-
Demuth T, Reavie LB, Rennert JL, Nakada M, Nakada S, Hoelzinger DB et al (2007). MAP-ing glioma invasion: mitogen-activated protein kinase kinase 3 and p38 drive glioma invasion and progression and predict patient survival. Mol Cancer Ther 6: 1212-1222.
-
(2007)
Mol Cancer Ther
, vol.6
, pp. 1212-1222
-
-
Demuth, T.1
Reavie, L.B.2
Rennert, J.L.3
Nakada, M.4
Nakada, S.5
Hoelzinger, D.B.6
-
5
-
-
0346463059
-
High intensity ras signaling induces premature senescence by activating p38 pathway in primary human fibroblasts
-
Deng Q, Liao R, Wu BL, Sun P. (2004). High intensity ras signaling induces premature senescence by activating p38 pathway in primary human fibroblasts. J Biol Chem 279: 1050-1059.
-
(2004)
J Biol Chem
, vol.279
, pp. 1050-1059
-
-
Deng, Q.1
Liao, R.2
Wu, B.L.3
Sun, P.4
-
6
-
-
0029761702
-
Signal-transducing protein phosphorylation cascades mediated by Ras/Rho proteins in the mammalian cell: The potential for multiplex signalling
-
Denhardt DT. (1996). Signal-transducing protein phosphorylation cascades mediated by Ras/Rho proteins in the mammalian cell: the potential for multiplex signalling. Biochem J 318(Part 3): 729-747.
-
(1996)
Biochem J
, vol.318
, Issue.PART 3
, pp. 729-747
-
-
Denhardt, D.T.1
-
7
-
-
0037264633
-
Targeting RAS signalling pathways in cancer therapy
-
Downward J. (2003). Targeting RAS signalling pathways in cancer therapy. Nat Rev Cancer 3: 11-22.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 11-22
-
-
Downward, J.1
-
8
-
-
62849100950
-
FOXM1 upregulation is an early event in human squamous cell carcinoma and it is enhanced by nicotine during malignant transformation
-
Gemenetzidis E, Bose A, Riaz AM, Chaplin T, Young BD, Ali M et al (2009). FOXM1 upregulation is an early event in human squamous cell carcinoma and it is enhanced by nicotine during malignant transformation. PLoS One 4: e4849.
-
(2009)
PLoS One
, vol.4
-
-
Gemenetzidis, E.1
Bose, A.2
Riaz, A.M.3
Chaplin, T.4
Young, B.D.5
Ali, M.6
-
9
-
-
33846006533
-
A cell-penetrating ARF peptide inhibitor of FoxM1 in mouse hepatocellular carcinoma treatment
-
Gusarova GA, Wang IC, Major ML, Kalinichenko VV, Ackerson T, Petrovic V et al (2007). A cell-penetrating ARF peptide inhibitor of FoxM1 in mouse hepatocellular carcinoma treatment. J Clin Invest 117: 99-111.
-
(2007)
J Clin Invest
, vol.117
, pp. 99-111
-
-
Gusarova, G.A.1
Wang, I.C.2
Major, M.L.3
Kalinichenko, V.V.4
Ackerson, T.5
Petrovic, V.6
-
10
-
-
0030044182
-
Characterization of the structure and function of a novel MAP kinase kinase (MKK6)
-
Han J, Lee JD, Jiang Y, Li Z, Feng L, Ulevitch RJ. (1996). Characterization of the structure and function of a novel MAP kinase kinase (MKK6). J Biol Chem 271: 2886-2891.
-
(1996)
J Biol Chem
, vol.271
, pp. 2886-2891
-
-
Han, J.1
Lee, J.D.2
Jiang, Y.3
Li, Z.4
Feng, L.5
Ulevitch, R.J.6
-
11
-
-
0036731380
-
Constitutive p38HOG mitogen-activated protein kinase activation induces permanent cell cycle arrest and senescence
-
Haq R, Brenton JD, Takahashi M, Finan D, Finkielsztein A, Damaraju S et al (2002). Constitutive p38HOG mitogen-activated protein kinase activation induces permanent cell cycle arrest and senescence. Cancer Res 62: 5076-5082.
-
(2002)
Cancer Res
, vol.62
, pp. 5076-5082
-
-
Haq, R.1
Brenton, J.D.2
Takahashi, M.3
Finan, D.4
Finkielsztein, A.5
Damaraju, S.6
-
12
-
-
14444281569
-
Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways
-
Ichijo H, Nishida E, Irie K, ten Dijke P, Saitoh M, Moriguchi T et al (1997). Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways. Science 275: 90-94.
-
(1997)
Science
, vol.275
, pp. 90-94
-
-
Ichijo, H.1
Nishida, E.2
Irie, K.3
Ten Dijke, P.4
Saitoh, M.5
Moriguchi, T.6
-
13
-
-
0033534611
-
Role of mitogen-activated protein kinases and c-Jun/AP-1 transactivating activity in the regulation of protease mRNAs and the malignant phenotype in NIH 3T3 fibroblasts
-
Janulis M, Silberman S, Ambegaokar A, Gutkind JS, Schultz RM. (1999). Role of mitogen-activated protein kinases and c-Jun/AP-1 transactivating activity in the regulation of protease mRNAs and the malignant phenotype in NIH 3T3 fibroblasts. J Biol Chem 274: 801-813.
-
(1999)
J Biol Chem
, vol.274
, pp. 801-813
-
-
Janulis, M.1
Silberman, S.2
Ambegaokar, A.3
Gutkind, J.S.4
Schultz, R.M.5
-
14
-
-
0029982565
-
Characterization of the structure and function of a new mito-gen-activated protein kinase (p38beta)
-
Jiang Y, Chen C, Li Z, Guo W, Gegner JA, Lin S et al (1996). Characterization of the structure and function of a new mito-gen-activated protein kinase (p38beta). J Biol Chem 271: 17920-17926.
-
(1996)
J Biol Chem
, vol.271
, pp. 17920-17926
-
-
Jiang, Y.1
Chen, C.2
Li, Z.3
Guo, W.4
Gegner, J.A.5
Lin, S.6
-
15
-
-
29644442895
-
The survival kinase Mirk/dyrk1B is activated through Rac1-MKK3 signaling
-
Jin K, Lim S, Mercer SE, Friedman E. (2005). The survival kinase Mirk/dyrk1B is activated through Rac1-MKK3 signaling. J Biol Chem 280: 42097-42105.
-
(2005)
J Biol Chem
, vol.280
, pp. 42097-42105
-
-
Jin, K.1
Lim, S.2
Mercer, S.E.3
Friedman, E.4
-
16
-
-
34547809513
-
P38alpha and p38delta mitogen-activated protein kinase isoforms regulate invasion and growth of head and neck squamous carcinoma cells
-
Junttila MR, Ala-Aho R, Jokilehto T, Peltonen J, Kallajoki M, Grenman R et al (2007). p38alpha and p38delta mitogen-activated protein kinase isoforms regulate invasion and growth of head and neck squamous carcinoma cells. Oncogene 26: 5267-5279.
-
(2007)
Oncogene
, vol.26
, pp. 5267-5279
-
-
Junttila, M.R.1
Ala-Aho, R.2
Jokilehto, T.3
Peltonen, J.4
Kallajoki, M.5
Grenman, R.6
-
17
-
-
32944459113
-
Increased levels of the FoxM1 transcription factor accelerate development and progression of prostate carcinomas in both TRAMP and LADY transgenic mice
-
Kalin TV, Wang IC, Ackerson TJ, Major ML, Detrisac CJ, Kalinichenko VV et al (2006). Increased levels of the FoxM1 transcription factor accelerate development and progression of prostate carcinomas in both TRAMP and LADY transgenic mice. Cancer Res 66: 1712-1720.
-
(2006)
Cancer Res
, vol.66
, pp. 1712-1720
-
-
Kalin, T.V.1
Wang, I.C.2
Ackerson, T.J.3
Major, M.L.4
Detrisac, C.J.5
Kalinichenko, V.V.6
-
18
-
-
0142088854
-
Sustained hepatic expression of FoxM1B in transgenic mice has minimal effects on hepatocellular carcinoma development but increases cell proliferation rates in preneoplastic and early neoplastic lesions
-
Kalinina OA, Kalinin SA, Polack EW, Mikaelian I, Panda S, Costa RH et al (2003). Sustained hepatic expression of FoxM1B in transgenic mice has minimal effects on hepatocellular carcinoma development but increases cell proliferation rates in preneoplastic and early neoplastic lesions. Oncogene 22: 6266-6276.
-
(2003)
Oncogene
, vol.22
, pp. 6266-6276
-
-
Kalinina, O.A.1
Kalinin, S.A.2
Polack, E.W.3
Mikaelian, I.4
Panda, S.5
Costa, R.H.6
-
19
-
-
0031573921
-
The human TRIDENT/HFH-11/FKHL16 gene: Structure, localization, and promoter characterization
-
Korver W, Roose J, Heinen K, Weghuis DO, de Bruijn D, van Kessel AG et al (1997). The human TRIDENT/HFH-11/FKHL16 gene: structure, localization, and promoter characterization. Genomics 46: 435-442.
-
(1997)
Genomics
, vol.46
, pp. 435-442
-
-
Korver, W.1
Roose, J.2
Heinen, K.3
Weghuis, D.O.4
De Bruijn, D.5
Van Kessel, A.G.6
-
20
-
-
0031587929
-
Novel homologues of CSBP/p38 MAP kinase: Activation, substrate specificity and sensitivity to inhibition by pyridinyl imidazoles
-
Kumar S, McDonnell PC, Gum RJ, Hand AT, Lee JC, Young PR. (1997). Novel homologues of CSBP/p38 MAP kinase: activation, substrate specificity and sensitivity to inhibition by pyridinyl imidazoles. Biochem Biophys Res Commun 235: 533-538.
-
(1997)
Biochem Biophys Res Commun
, vol.235
, pp. 533-538
-
-
Kumar, S.1
McDonnell, P.C.2
Gum, R.J.3
Hand, A.T.4
Lee, J.C.5
Young, P.R.6
-
21
-
-
13944274222
-
FoxM1 is required for execution of the mitotic programme and chromosome stability
-
Laoukili J, Kooistra MR, Bras A, Kauw J, Kerkhoven RM, Morrison A et al (2005). FoxM1 is required for execution of the mitotic programme and chromosome stability. Nat Cell Biol 7: 126-136.
-
(2005)
Nat Cell Biol
, vol.7
, pp. 126-136
-
-
Laoukili, J.1
Kooistra, M.R.2
Bras, A.3
Kauw, J.4
Kerkhoven, R.M.5
Morrison, A.6
-
23
-
-
33644799866
-
Differential functions of Ras for malignant phenotypic conversion
-
Moon A. (2006). Differential functions of Ras for malignant phenotypic conversion. Arch Pharm Res 29: 113-122.
-
(2006)
Arch Pharm Res
, vol.29
, pp. 113-122
-
-
Moon, A.1
-
24
-
-
33846048058
-
Transcription factors control invasion: AP-1 the first among equals
-
Ozanne BW, Spence HJ, McGarry LC, Hennigan RF. (2007). Transcription factors control invasion: AP-1 the first among equals. Oncogene 26: 1-10.
-
(2007)
Oncogene
, vol.26
, pp. 1-10
-
-
Ozanne, B.W.1
Spence, H.J.2
McGarry, L.C.3
Hennigan, R.F.4
-
25
-
-
70350572180
-
FoxM1, a critical regulator of oxidative stress during oncogenesis
-
Park HJ, Carr JR, Wang Z, Nogueira V, Hay N, Tyner AL et al (2009). FoxM1, a critical regulator of oxidative stress during oncogenesis. EMBO J 28: 2908-2918.
-
(2009)
EMBO J
, vol.28
, pp. 2908-2918
-
-
Park, H.J.1
Carr, J.R.2
Wang, Z.3
Nogueira, V.4
Hay, N.5
Tyner, A.L.6
-
26
-
-
11144280578
-
Identification and validation of commonly overexpressed genes in solid tumors by comparison of microarray data
-
Pilarsky C, Wenzig M, Specht T, Saeger HD, Grutzmann R. (2004). Identification and validation of commonly overexpressed genes in solid tumors by comparison of microarray data. Neoplasia 6: 744-750.
-
(2004)
Neoplasia
, vol.6
, pp. 744-750
-
-
Pilarsky, C.1
Wenzig, M.2
Specht, T.3
Saeger, H.D.4
Grutzmann, R.5
-
27
-
-
33747872178
-
P38gamma mitogen-activated protein kinase integrates signaling crosstalk between Ras and estrogen receptor to increase breast cancer invasion
-
Qi X, Tang J, Loesch M, Pohl N, Alkan S, Chen G. (2006). p38gamma mitogen-activated protein kinase integrates signaling crosstalk between Ras and estrogen receptor to increase breast cancer invasion. Cancer Res 66: 7540-7547.
-
(2006)
Cancer Res
, vol.66
, pp. 7540-7547
-
-
Qi, X.1
Tang, J.2
Loesch, M.3
Pohl, N.4
Alkan, S.5
Chen, G.6
-
28
-
-
0030051528
-
MKK3-and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway
-
Raingeaud J, Whitmarsh AJ, Barrett T, Derijard B, Davis RJ. (1996). MKK3-and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway. Mol Cell Biol 16: 1247-1255.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 1247-1255
-
-
Raingeaud, J.1
Whitmarsh, A.J.2
Barrett, T.3
Derijard, B.4
Davis, R.J.5
-
29
-
-
34248597065
-
Differential regulation and properties of MAPKs
-
Raman M, Chen W, Cobb MH. (2007). Differential regulation and properties of MAPKs. Oncogene 26: 3100-3112.
-
(2007)
Oncogene
, vol.26
, pp. 3100-3112
-
-
Raman, M.1
Chen, W.2
Cobb, M.H.3
-
30
-
-
0037200088
-
Activation of p38 alpha MAPK enhances collagenase-1 (matrix metalloproteinase (MMP)-1) and stromelysin-1 (MMP-3) expression by mRNA stabilization
-
Reunanen N, Li SP, Ahonen M, Foschi M, Han J, Kahari VM. (2002). Activation of p38 alpha MAPK enhances collagenase-1 (matrix metalloproteinase (MMP)-1) and stromelysin-1 (MMP-3) expression by mRNA stabilization. J Biol Chem 277: 32360-32368.
-
(2002)
J Biol Chem
, vol.277
, pp. 32360-32368
-
-
Reunanen, N.1
Li, S.P.2
Ahonen, M.3
Foschi, M.4
Han, J.5
Kahari, V.M.6
-
31
-
-
0032935664
-
Mitogen-activated protein kinases: Specific messages from ubiquitous messengers
-
Schaeffer HJ, Weber MJ. (1999). Mitogen-activated protein kinases: specific messages from ubiquitous messengers. Mol Cell Biol 19: 2435-2444.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 2435-2444
-
-
Schaeffer, H.J.1
Weber, M.J.2
-
32
-
-
34248179139
-
The potential for signal integration and processing in interacting MAP kinase cascades
-
Schwacke JH, Voit EO. (2007). The potential for signal integration and processing in interacting MAP kinase cascades. J Theor Biol 246: 604-620.
-
(2007)
J Theor Biol
, vol.246
, pp. 604-620
-
-
Schwacke, J.H.1
Voit, E.O.2
-
33
-
-
17644367566
-
H-Ras-specific activation of Rac-MKK3/6-p38 pathway: Its critical role in invasion and migration of breast epithelial cells
-
Shin I, Kim S, Song H, Kim HR, Moon A. (2005). H-Ras-specific activation of Rac-MKK3/6-p38 pathway: its critical role in invasion and migration of breast epithelial cells. J Biol Chem 280: 14675-14683.
-
(2005)
J Biol Chem
, vol.280
, pp. 14675-14683
-
-
Shin, I.1
Kim, S.2
Song, H.3
Kim, H.R.4
Moon, A.5
-
34
-
-
33751270700
-
Activating transcription factor 2 mediates matrix metalloproteinase-2 transcriptional activation induced by p38 in breast epithelial cells
-
Song H, Ki SH, Kim SG, Moon A. (2006). Activating transcription factor 2 mediates matrix metalloproteinase-2 transcriptional activation induced by p38 in breast epithelial cells. Cancer Res 66: 10487-10496.
-
(2006)
Cancer Res
, vol.66
, pp. 10487-10496
-
-
Song, H.1
Ki, S.H.2
Kim, S.G.3
Moon, A.4
-
35
-
-
0021184853
-
Transformation of NIH 3T3 cells by microinjection of Ha-ras p21 protein
-
Stacey DW, Kung HF. (1984). Transformation of NIH 3T3 cells by microinjection of Ha-ras p21 protein. Nature 310: 508-511.
-
(1984)
Nature
, vol.310
, pp. 508-511
-
-
Stacey, D.W.1
Kung, H.F.2
-
36
-
-
33846282393
-
PRAK is essential for ras-induced senescence and tumor suppression
-
Sun P, Yoshizuka N, New L, Moser BA, Li Y, Liao R et al (2007). PRAK is essential for ras-induced senescence and tumor suppression. Cell 128: 295-308.
-
(2007)
Cell
, vol.128
, pp. 295-308
-
-
Sun, P.1
Yoshizuka, N.2
New, L.3
Moser, B.A.4
Li, Y.5
Liao, R.6
-
37
-
-
36248990364
-
FOXM1, a typical proliferation-associated transcription factor
-
Wierstra I, Alves J. (2007). FOXM1, a typical proliferation-associated transcription factor. Biol Chem 388: 1257-1274.
-
(2007)
Biol Chem
, vol.388
, pp. 1257-1274
-
-
Wierstra, I.1
Alves, J.2
-
38
-
-
34247221487
-
The forkhead box M1 transcription factor contributes to the development and growth of mouse colorectal cancer
-
Yoshida Y, Wang IC, Yoder HM, Davidson NO, Costa RH. (2007). The forkhead box M1 transcription factor contributes to the development and growth of mouse colorectal cancer. Gastro-enterology 132: 1420-1431.
-
(2007)
Gastro-enterology
, vol.132
, pp. 1420-1431
-
-
Yoshida, Y.1
Wang, I.C.2
Yoder, H.M.3
Davidson, N.O.4
Costa, R.H.5
-
39
-
-
0026483206
-
Fibroblasts transformed by different ras oncogenes show dissimilar patterns of protease gene expression and regulation
-
Zhang JY, Schultz RM. (1992). Fibroblasts transformed by different ras oncogenes show dissimilar patterns of protease gene expression and regulation. Cancer Res 52: 6682-6689.
-
(1992)
Cancer Res
, vol.52
, pp. 6682-6689
-
-
Zhang, J.Y.1
Schultz, R.M.2
|