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Volumn 13, Issue 2, 2012, Pages 203-214

Interplay of β-catenin with xenobiotic-sensing receptors and its role in glutathione S-transferase expression

Author keywords

catenin; Aryl hydrocarbon receptor; Constitutive androstane receptor; Drug metabolism; Liver tumor; Metabolic zonation; Phase II; Wnt signaling

Indexed keywords

BETA CATENIN; CONSTITUTIVE ANDROSTANE RECEPTOR; GLUTATHIONE TRANSFERASE; HEPATOCYTE NUCLEAR FACTOR 4ALPHA; RECEPTOR; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR NRF2; TRANSCRIPTION FACTOR PXR; UNCLASSIFIED DRUG; WNT PROTEIN; XENOBIOTIC SENSING RECEPTOR;

EID: 84857564987     PISSN: 13892002     EISSN: 18755453     Source Type: Journal    
DOI: 10.2174/138920012798918381     Document Type: Article
Times cited : (6)

References (116)
  • 1
    • 78649670044 scopus 로고    scopus 로고
    • The Wnt/beta-catenin signaling pathway in liver biology and disease
    • Behari, J. The Wnt/beta-catenin signaling pathway in liver biology and disease. Expert Rev. Gastroenterol. Hepatol., 2010, 4, 745-756.
    • (2010) Expert Rev. Gastroenterol. Hepatol. , vol.4 , pp. 745-756
    • Behari, J.1
  • 2
    • 34248674146 scopus 로고    scopus 로고
    • WNT/α-catenin signaling in liver health and disease
    • DOI 10.1002/hep.21651
    • Thompson, M.D.; Monga, S.P. WNT/beta-catenin signaling in liver health and disease. Hepatology, 2007, 45, 1298-1305. (Pubitemid 46775794)
    • (2007) Hepatology , vol.45 , Issue.5 , pp. 1298-1305
    • Thompson, M.D.1    Monga, S.P.S.2
  • 3
    • 73949116718 scopus 로고    scopus 로고
    • Organ patterning in the adult stage: The role of Wnt/beta-catenin signaling in liver zonation and beyond
    • Gebhardt, R; Hovhannisyan, A. Organ patterning in the adult stage: The role of Wnt/beta-catenin signaling in liver zonation and beyond. Dev. Dyn., 2010, 239, 45-55.
    • (2010) Dev. Dyn. , vol.239 , pp. 45-55
    • Gebhardt, R.1    Hovhannisyan, A.2
  • 4
    • 78651429899 scopus 로고    scopus 로고
    • Transcription dynamics in a physiological process: Beta-Catenin signaling directs liver metabolic zonation
    • Torre, C.; Perret, C.; Colnot, S. Transcription dynamics in a physiological process: Beta-Catenin signaling directs liver metabolic zonation. Int. J. Biochem. Cell Biol., 2011, 43, 271-278.
    • (2011) Int. J. Biochem. Cell Biol. , vol.43 , pp. 271-278
    • Torre, C.1    Perret, C.2    Colnot, S.3
  • 5
    • 5444265502 scopus 로고    scopus 로고
    • The Wnt connection to tumorigenesis
    • DOI 10.1387/ijdb.041815jb, Invasion in Cancer and Embryonic Development
    • Behrens, J.; Lustig, B. The Wnt connection to tumorigenesis. Int. J. Dev. Biol., 2004, 48, 477-487. (Pubitemid 39360398)
    • (2004) International Journal of Developmental Biology , vol.48 , Issue.5-6 , pp. 477-487
    • Behrens, J.1    Lustig, B.2
  • 7
    • 59049093707 scopus 로고    scopus 로고
    • Wnt signaling in liver cancer
    • Takigawa, Y.; Brown, A.M. Wnt signaling in liver cancer. Curr. Drug Targets, 2008, 9, 1013-1024.
    • (2008) Curr. Drug Targets , vol.9 , pp. 1013-1024
    • Takigawa, Y.1    Brown, A.M.2
  • 8
    • 77956627711 scopus 로고    scopus 로고
    • The role of signaling pathways in the development and treatment of hepatocellular carcinoma
    • Whittaker, S.; Marais, R.; Zhu, A.X. The role of signaling pathways in the development and treatment of hepatocellular carcinoma. Oncogene, 2010, 29, 4989-5005.
    • (2010) Oncogene , vol.29 , pp. 4989-5005
    • Whittaker, S.1    Marais, R.2    Zhu, A.X.3
  • 10
    • 67650230896 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling: Components, mechanisms, and diseases
    • MacDonald, B.T.; Tamai, K.; He, X. Wnt/beta-catenin signaling: Components, mechanisms, and diseases. Dev. Cell, 2009, 17, 9-26.
    • (2009) Dev. Cell , vol.17 , pp. 9-26
    • MacDonald, B.T.1    Tamai, K.2    He, X.3
  • 11
    • 0036534586 scopus 로고    scopus 로고
    • TCF transcription factors, mediators of Wnt-signaling in development and cancer
    • DOI 10.1006/dbio.2001.0566
    • van Noort, M.; Clevers, H. TCF transcription factors, mediators of Wnt-signaling in development and cancer. Dev. Biol., 2002, 244, 1-8. (Pubitemid 34271136)
    • (2002) Developmental Biology , vol.244 , Issue.1 , pp. 1-8
    • Van Noort, M.1    Clevers, H.2
  • 12
    • 0031888098 scopus 로고    scopus 로고
    • α-catenin: A key mediator of Wnt signaling
    • DOI 10.1016/S0959-437X(98)80068-3
    • Willert, K.; Nusse, R. Beta-catenin: A key mediator of Wnt signaling. Curr. Opin. Genet. Dev., 1998, 8, 95-102. (Pubitemid 28122147)
    • (1998) Current Opinion in Genetics and Development , vol.8 , Issue.1 , pp. 95-102
    • Willert, K.1    Nusse, R.2
  • 13
    • 33645989449 scopus 로고    scopus 로고
    • Liverspecific loss of β-catenin blocks glutamine synthetis pathway activity and cytochrome P450 expression in mice
    • Sekine, S.; Lan, B.Y.A.; Bedolli, M.; Feng, S.; Hebrok, M. Liverspecific loss of β-catenin blocks glutamine synthetis pathway activity and cytochrome P450 expression in mice. Hepatology, 2006, 43, 817-825.
    • (2006) Hepatology , vol.43 , pp. 817-825
    • Sekine, S.1    Lan, B.Y.A.2    Bedolli, M.3    Feng, S.4    Hebrok, M.5
  • 16
    • 0031972732 scopus 로고    scopus 로고
    • Zonation of hepatic cytochrome P-450 expression and regulation
    • Oinonen, T.; Lindros, K.O. Zonation of hepatic cytochrome P-450 expression and regulation. Biochem. J., 1998, 329, 17-35. (Pubitemid 28022286)
    • (1998) Biochemical Journal , vol.329 , Issue.1 , pp. 17-35
    • Oinonen, T.1    Lindros, K.O.2
  • 17
    • 0031012845 scopus 로고    scopus 로고
    • Zonation of cytochrome P450 expression, drug metabolism and toxicity in liver
    • DOI 10.1016/S0306-3623(96)00183-8, PII S0306362396001838
    • Lindros, K.O. Zonation of cytochrome P450 expression, drug metabolism and toxicity in liver. Gen. Pharmacol., 1997, 28, 191-196. (Pubitemid 27016124)
    • (1997) General Pharmacology , vol.28 , Issue.2 , pp. 191-196
    • Lindros, K.O.1
  • 18
    • 0026766117 scopus 로고
    • Metabolic zonation of the liver: Regulation and implications for liver function
    • Gebhardt, R. Metabolic zonation of the liver: Regulation and implications for liver function. Pharmacol. Ther., 1992, 53, 275-354.
    • (1992) Pharmacol. Ther. , vol.53 , pp. 275-354
    • Gebhardt, R.1
  • 19
    • 33750726092 scopus 로고    scopus 로고
    • Conditional Deletion of α-Catenin Reveals Its Role in Liver Growth and Regeneration
    • DOI 10.1053/j.gastro.2006.08.042, PII S0016508506018026
    • Tan, X.; Behari, J.; Cieply, B.; Michalopoulos, G.K.; Monga, S.P. Conditional deletion of beta-catenin reveals its role in liver growth and regeneration. Gastroenterology, 2006, 131, 1561-1572. (Pubitemid 44708943)
    • (2006) Gastroenterology , vol.131 , Issue.5 , pp. 1561-1572
    • Tan, X.1    Behari, J.2    Cieply, B.3    Michalopoulos, G.K.4    Monga, S.P.S.5
  • 20
    • 34047157076 scopus 로고    scopus 로고
    • Zonal gene expression in mouse liver resembles expression patterns of Ha-ras and α-catenin mutated hepatomas
    • DOI 10.1124/dmd.106.013656
    • Braeuning, A.; Ittrich, C.; Kohle, C.; Buchmann, A.; Schwarz, M. Zonal gene expression in mouse liver resembles expression patterns of Ha-ras and beta-catenin mutated hepatomas. Drug Metab. Dispos., 2007, 35, 503-507. (Pubitemid 46513275)
    • (2007) Drug Metabolism and Disposition , vol.35 , Issue.4 , pp. 503-507
    • Braeuning, A.1    Ittrich, C.2    Kohle, C.3    Buchmann, A.4    Schwarz, M.5
  • 21
    • 66449102968 scopus 로고    scopus 로고
    • Inducibility of drug-metabolizing enzymes by xenobiotics in mice with liverspecific knockout of ctnnb1
    • Braeuning, A.; Sanna, R.; Huelsken, J.; Schwarz, M. Inducibility of Drug-metabolizing Enzymes by Xenobiotics in Mice with Liverspecific Knockout of Ctnnb1. Drug Metab. Dispos., 2009, 37, 1138-1145.
    • (2009) Drug Metab. Dispos. , vol.37 , pp. 1138-1145
    • Braeuning, A.1    Sanna, R.2    Huelsken, J.3    Schwarz, M.4
  • 22
    • 65549136561 scopus 로고    scopus 로고
    • Regulation of cytochrome p450 expression by rasand Beta catenin-dependent signaling
    • Braeuning, A. Regulation of cytochrome p450 expression by rasand Beta catenin-dependent signaling. Curr. Drug Metab., 2009, 10, 138-158.
    • (2009) Curr. Drug Metab. , vol.10 , pp. 138-158
    • Braeuning, A.1
  • 23
    • 77749336635 scopus 로고    scopus 로고
    • Beta-Catenin as a Multilayer Modulator of Zonal Cytochrome P450 Expression in Mouse Liver
    • Braeuning, A.; Schwarz, M. beta-Catenin as a Multilayer Modulator of Zonal Cytochrome P450 Expression in Mouse Liver. Biol. Chem., 2010, 391, 139-148.
    • (2010) Biol. Chem. , vol.391 , pp. 139-148
    • Braeuning, A.1    Schwarz, M.2
  • 25
    • 79952118383 scopus 로고    scopus 로고
    • Tumor Formation in Liver of Conditional beta-Catenin-Deficient Mice Exposed to a Diethylnitrosamine /Phenobarbital Tumor Promotion Regimen
    • Rignall, B.; Braeuning, A.; Buchmann, A.; Schwarz, M. Tumor Formation in Liver of Conditional beta-Catenin-Deficient Mice Exposed to a Diethylnitrosamine /Phenobarbital Tumor Promotion Regimen. Carcinogenesis, 2011, 32, 52-57.
    • (2011) Carcinogenesis , vol.32 , pp. 52-57
    • Rignall, B.1    Braeuning, A.2    Buchmann, A.3    Schwarz, M.4
  • 29
    • 0023248470 scopus 로고
    • Acinar distribution of glutathione-dependent detoxifying enzymes. Low glutathione peroxidase activity in perivenous hepatocytes
    • DOI 10.1016/0006-2952(87)90500-4
    • Kera, Y.; Sippel, H.W.; Penttila, K.E.; Lindros, K.O. Acinar distribution of glutathione-dependent detoxifying enzymes. Low glutathione peroxidase activity in perivenous hepatocytes. Biochem. Pharmacol., 1987, 36, 2003-2006. (Pubitemid 17100223)
    • (1987) Biochemical Pharmacology , vol.36 , Issue.12 , pp. 2003-2006
    • Kera, Y.1    Sippel, H.W.2    Penttila, K.E.3    Lindros, K.O.4
  • 30
    • 0024507027 scopus 로고
    • Drug metabolism by periportal and perivenous rat hepatocytes. Comparison of phase I and phase II reactions and their inducibility during culture
    • DOI 10.1016/0006-2952(89)90340-7
    • Suolinna, E.M.; Penttila, K.E.; Winell, B.M.; Sjoholm, A.C.; Lindros, K.O. Drug metabolism by periportal and perivenous rat hepatocytes. Comparison of phase I and phase II reactions and their inducibility during culture. Biochem. Pharmacol., 1989, 38, 1329-1334. (Pubitemid 19101963)
    • (1989) Biochemical Pharmacology , vol.38 , Issue.8 , pp. 1329-1334
    • Suolinna, E.-M.1    Penttila, K.E.2    Winell, B.-M.3    Sjoholm, A.-C.4    Lindros, K.O.5
  • 31
    • 0032519657 scopus 로고    scopus 로고
    • Aryl hydrocarbon receptor-Associated genes in rat liver: Regional coinduction of aldehyde dehydrogenase 3 and glutathione transferase Ya
    • Lindros, K.O.; Oinonen, T.; Kettunen, E.; Sippel, H., Muro-Lupori, C.; Koivusalo, M. Aryl hydrocarbon receptor-Associated genes in rat liver: Regional coinduction of aldehyde dehydrogenase 3 and glutathione transferase Ya. Biochem. Pharmacol., 1998, 55, 413-421.
    • (1998) Biochem. Pharmacol. , vol.55 , pp. 413-421
    • Lindros, K.O.1    Oinonen, T.2    Kettunen, E.3    Sippel, H.4    Muro-Lupori, C.5    Koivusalo, M.6
  • 32
    • 0029835925 scopus 로고    scopus 로고
    • Distribution of glutathione S-transferase isoforms in rat liver after induction by α-naphthoflavone or 3-methylcholanthrene
    • Sippel, H.; Lindros, K.O.; Oinonen, T. Distribution of glutathione S-transferase isoforms in rat liver after induction by betanaphthoflavone or 3-methylcholanthrene. Pharmacol. Toxicol., 1996, 79, 80-86. (Pubitemid 26276669)
    • (1996) Pharmacology and Toxicology , vol.79 , Issue.2 , pp. 80-86
    • Sippel, H.1    Lindros, K.O.2    Oinonen, T.3
  • 33
    • 0025806317 scopus 로고
    • Regioselective induction of liver glutathione transferase by ethanol and acetone
    • Sippel, H.; Penttila, K.E.; Lindros, K.O. Regioselective induction of liver glutathione transferase by ethanol and acetone. Pharmacol. Toxicol., 1991, 68, 391-393.
    • (1991) Pharmacol. Toxicol. , vol.68 , pp. 391-393
    • Sippel, H.1    Penttila, K.E.2    Lindros, K.O.3
  • 35
    • 0034824345 scopus 로고    scopus 로고
    • Effect of oxygen concentration on the expression of glutathione S-transferase activity in periportal and perivenous rat hepatocyte cultures
    • DOI 10.1016/S0887-2333(01)00041-8, PII S0887233301000418
    • Vanhaecke, T.; Elaut, G.; Rogiers, V. Effect of oxygen concentration on the expression of glutathione S-transferase activity in periportal and perivenous rat hepatocyte cultures. Toxicol. In Vitro, 2001, 15, 387-392. (Pubitemid 32889663)
    • (2001) Toxicology in Vitro , vol.15 , Issue.4-5 , pp. 387-392
    • Vanhaecke, T.1    Elaut, G.2    Rogiers, V.3
  • 36
    • 79551686173 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling activates and determines hepatic zonal expression of glutathione Stransferases in mouse liver
    • Giera, S.; Braeuning, A.; Kohle, C.; Bursch, W.; Metzger, U.; Buchmann, A.; Schwarz, M. Wnt/beta-catenin signaling activates and determines hepatic zonal expression of glutathione Stransferases in mouse liver. Toxicol. Sci., 2010, 115, 22-33.
    • (2010) Toxicol. Sci. , vol.115 , pp. 22-33
    • Giera, S.1    Braeuning, A.2    Kohle, C.3    Bursch, W.4    Metzger, U.5    Buchmann, A.6    Schwarz, M.7
  • 38
    • 34948894599 scopus 로고    scopus 로고
    • Proteome analysis of chemically induced mouse liver tumors with different genotype
    • DOI 10.1002/pmic.200600983
    • Strathmann, J.; Paal, K.; Ittrich, C.; Krause, E.; Appel, K.E.; Glauert, H.P.; Buchmann, A.; Schwarz, M. Proteome analysis of chemically induced mouse liver tumors with different genotype. Proteomics, 2007, 7, 3318-3331. (Pubitemid 47517947)
    • (2007) Proteomics , vol.7 , Issue.18 , pp. 3318-3331
    • Strathmann, J.1    Paal, K.2    Ittrich, C.3    Krause, E.4    Appel, K.E.5    Glauert, H.P.6    Buchmann, A.7    Schwarz, M.8
  • 39
    • 71049143563 scopus 로고    scopus 로고
    • Hepatocellular carcinoma development induced by conditional beta-catenin activation in Lkb1+/-mice
    • Miyoshi, H.; Deguchi, A.; Nakau, M.; Kojima, Y.; Mori, A.; Oshima, M.; Aoki, M.; Taketo, M.M. Hepatocellular carcinoma development induced by conditional beta-catenin activation in Lkb1+/-mice. Cancer Sci., 2009, 100, 2046-2053.
    • (2009) Cancer Sci. , vol.100 , pp. 2046-2053
    • Miyoshi, H.1    Deguchi, A.2    Nakau, M.3    Kojima, Y.4    Mori, A.5    Oshima, M.6    Aoki, M.7    Taketo, M.M.8
  • 41
    • 68549094627 scopus 로고    scopus 로고
    • Comparative transcriptome and proteome analysis of Ha-ras and B-raf mutated mouse liver tumors
    • Rignall, B.; Ittrich, C.; Krause, E.; Appel, K.E.; Buchmann, A.; Schwarz, M. Comparative transcriptome and proteome analysis of Ha-ras and B-raf mutated mouse liver tumors. J. Proteome Res., 2009, 8, 3987-3994.
    • (2009) J. Proteome Res. , vol.8 , pp. 3987-3994
    • Rignall, B.1    Ittrich, C.2    Krause, E.3    Appel, K.E.4    Buchmann, A.5    Schwarz, M.6
  • 42
    • 0020699358 scopus 로고
    • Heterogeneous distribution of glutamine synthetase among rat liver parenchymal cells in situ and in primary culture
    • Gebhardt, R.; Mecke, D. Heterogeneous distribution of glutamine synthetase among rat liver parenchymal cells in situ and in primary culture. Embo J., 1983, 2, 567-570.
    • (1983) Embo J. , vol.2 , pp. 567-570
    • Gebhardt, R.1    Mecke, D.2
  • 43
    • 33947139689 scopus 로고    scopus 로고
    • Hepatocellular expression of glutamine synthetase: An indicator of morphogen actions as master regulators of zonation in adult liver
    • DOI 10.1016/j.proghi.2006.12.001, PII S0079633606000702
    • Gebhardt, R.; Baldysiak-Figiel, A.; Krugel, V.; Ueberham, E.; Gaunitz, F. Hepatocellular expression of glutamine synthetase: An indicator of morphogen actions as master regulators of zonation in adult liver. Prog. Histochem. Cytochem., 2007, 41, 201-266. (Pubitemid 46412421)
    • (2007) Progress in Histochemistry and Cytochemistry , vol.41 , Issue.4 , pp. 201-266
    • Gebhardt, R.1    Baldysiak-Figiel, A.2    Krugel, V.3    Ueberham, E.4    Gaunitz, F.5
  • 44
    • 0037108681 scopus 로고    scopus 로고
    • Overexpression of glutamine synthetase is associated with α-catenin-mutations in mouse liver tumors during promotion of hepatocarcinogenesis by phenobarbital
    • Loeppen, S.; Schneider, D.; Gaunitz, F.; Gebhardt, R.; Kurek, R.; Buchmann, A.; Schwarz, M. Overexpression of glutamine synthetase is associated with beta-catenin-mutations in mouse livertumors during promotion of hepatocarcinogenesis by phenobarbital. Cancer Res., 2002, 62, 5685-5688. (Pubitemid 35204722)
    • (2002) Cancer Research , vol.62 , Issue.20 , pp. 5685-5688
    • Loeppen, S.1    Schneider, D.2    Gaunitz, F.3    Gebhardt, R.4    Kurek, R.5    Buchmann, A.6    Schwarz, M.7
  • 45
    • 0037191930 scopus 로고    scopus 로고
    • New targets of α-catenin signaling in the liver are involved in the glutamine metabolism
    • DOI 10.1038/sj.onc.1206118
    • Cadoret, A.; Ovejero, C.; Terris, B.; Souil, E.; Levy, L.; Lamers, W.H.; Kitajewski, J.; Kahn, A.; Perret, C. New targets of betacatenin signaling in the liver are involved in the glutamine metabolism. Oncogene, 2002, 21, 8293-8301. (Pubitemid 35477869)
    • (2002) Oncogene , vol.21 , Issue.54 , pp. 8293-8301
    • Cadoret, A.1    Ovejero, C.2    Terris, B.3    Souil, E.4    Levy, L.5    Lamers, W.H.6    Kitajewski, J.7    Kahn, A.8    Perret, C.9
  • 47
    • 0035936026 scopus 로고    scopus 로고
    • Selective pressure during tumor promotion by phenobarbital leads to clonal outgrowth of α-catenin-mutated mouse liver tumors
    • DOI 10.1038/sj/onc/1204982
    • Aydinlik, H.; Nguyen, T.D.; Moennikes, O.; Buchmann, A.; Schwarz, M. Selective pressure during tumor promotion by phenobarbital leads to clonal outgrowth of beta-catenin-mutated mouse liver tumors. Oncogene, 2001, 20, 7812-7816. (Pubitemid 33121956)
    • (2001) Oncogene , vol.20 , Issue.53 , pp. 7812-7816
    • Aydinlik, H.1    Nguyen, T.D.2    Moennikes, O.3    Buchmann, A.4    Schwarz, M.5
  • 48
    • 20344376405 scopus 로고    scopus 로고
    • Effect of the tumor promoter phenobarbital on the pattern of global gene expression in liver of connexin32-wild-type and connexin32-deficient mice
    • DOI 10.1002/ijc.20815
    • Stahl, S.; Ittrich, C.; Marx-Stoelting, P.; Kohle, C.; Altug-Teber, O.; Riess, O.; Bonin, M.; Jobst, J.; Kaiser, S.; Buchmann, A.; Schwarz, M. Effect of the tumor promoter phenobarbital on the pattern of global gene expression in liver of connexin32-wild-type and connexin32-deficient mice. Int. J. Cancer, 2005, 115, 861-869. (Pubitemid 40791825)
    • (2005) International Journal of Cancer , vol.115 , Issue.6 , pp. 861-869
    • Stahl, S.1    Ittrich, C.2    Marx-Stoelting, P.3    Kohle, C.4    Ott, T.5    Buchmann, A.6    Schwarz, M.7
  • 49
    • 52449108842 scopus 로고    scopus 로고
    • New insights on the xenobiotic-sensing nuclear receptors in liver diseases-CAR and PXR
    • Kakizaki, S.; Yamazaki, Y.; Takizawa, D.; Negishi, M. New insights on the xenobiotic-sensing nuclear receptors in liver diseases-CAR and PXR. Curr. Drug Metab., 2008, 9, 614-621.
    • (2008) Curr. Drug Metab. , vol.9 , pp. 614-621
    • Kakizaki, S.1    Yamazaki, Y.2    Takizawa, D.3    Negishi, M.4
  • 50
    • 34247349605 scopus 로고    scopus 로고
    • Nuclear receptors and the regulation of drug-metabolizing enzymes and drug transporters: Implications for interindividual variability in response to drugs
    • DOI 10.1177/0091270007299930
    • Urquhart, B.L.; Tirona, R.G.; Kim, R.B. Nuclear receptors and the regulation of drug-metabolizing enzymes and drug transporters: Implications for interindividual variability in response to drugs. J. Clin. Pharmacol., 2007, 47, 566-578. (Pubitemid 46632158)
    • (2007) Journal of Clinical Pharmacology , vol.47 , Issue.5 , pp. 566-578
    • Urquhart, B.L.1    Tirona, R.G.2    Kim, R.B.3
  • 51
    • 18144405011 scopus 로고    scopus 로고
    • Apoptosis in stages of mouse hepatocarcinogenesis: Failure to counterbalance cell proliferation and to account for strain differences in tumor susceptibility
    • DOI 10.1093/toxsci/kfi129
    • Bursch, W.; Chabicovsky, M.; Wastl, U.; Grasl-Kraupp, B.; Bukowska, K.; Taper, H.; Schulte-Hermann, R. Apoptosis in stages of mouse hepatocarcinogenesis: Failure to counterbalance cell proliferation and to account for strain differences in tumor susceptibility. Toxicol. Sci., 2005, 85, 515-529. (Pubitemid 40614281)
    • (2005) Toxicological Sciences , vol.85 , Issue.1 , pp. 515-529
    • Bursch, W.1    Chabicovsky, M.2    Wastl, U.3    Grasl-Kraupp, B.4    Bukowska, K.5    Taper, H.6    Schulte-Hermann, R.7
  • 52
    • 79955522873 scopus 로고    scopus 로고
    • The pharmacokinetics of commonly used antiepileptic drugs in immature CD1 mice
    • Markowitz, G.J.; Kadam, S.D.; Boothe, D.M.; Irving, N.D.; Comi, A.M. The pharmacokinetics of commonly used antiepileptic drugs in immature CD1 mice. Neuroreport, 2010, 21, 452-456.
    • (2010) Neuroreport , vol.21 , pp. 452-456
    • Markowitz, G.J.1    Kadam, S.D.2    Boothe, D.M.3    Irving, N.D.4    Comi, A.M.5
  • 53
    • 78649351055 scopus 로고    scopus 로고
    • Zonation of heme synthesis enzymes in mouse liver and their regulation by beta-catenin and Ha-ras
    • Braeuning, A.; Schwarz, M. Zonation of heme synthesis enzymes in mouse liver and their regulation by beta-catenin and Ha-ras. Biol Chem., 2010, 391, 1305-1313.
    • (2010) Biol Chem. , vol.391 , pp. 1305-1313
    • Braeuning, A.1    Schwarz, M.2
  • 54
    • 79961004343 scopus 로고    scopus 로고
    • Coordinate Regulation of Cytochrome P450 1A1 Expression in Mouse Liver by the Aryl Hydrocarbon Receptor and the beta-Catenin Pathway
    • Braeuning, A.; Kohle, C.; Buchmann, A.; Schwarz, M. Coordinate Regulation of Cytochrome P450 1A1 Expression in Mouse Liver by the Aryl Hydrocarbon Receptor and the beta-Catenin Pathway. Toxicol. Sci., 2011, 122, 16-25.
    • (2011) Toxicol. Sci. , vol.122 , pp. 16-25
    • Braeuning, A.1    Kohle, C.2    Buchmann, A.3    Schwarz, M.4
  • 56
    • 79953679564 scopus 로고    scopus 로고
    • Hepatomas with activating Ctnnb1 mutations in 'Ctnnb1-deficient' livers: A tricky aspect of a conditional knockout mouse model
    • Sekine, S.; Ogawa, R.; Kanai, Y. Hepatomas with activating Ctnnb1 mutations in 'Ctnnb1-deficient' livers: A tricky aspect of a conditional knockout mouse model. Carcinogenesis, 2011, 32, 622-628.
    • (2011) Carcinogenesis , vol.32 , pp. 622-628
    • Sekine, S.1    Ogawa, R.2    Kanai, Y.3
  • 57
    • 77956632050 scopus 로고    scopus 로고
    • Conditional beta-catenin loss in mice promotes chemical hepatocarcinogenesis: Role of oxidative stress and platelet-derived growth factor receptor alpha/phosphoinositide 3-kinase signaling
    • Zhang, X.F.; Tan, X.; Zeng, G.; Misse, A.; Singh, S.; Kim, Y.; Klaunig, J.E.; Monga, S.P. Conditional beta-catenin loss in mice promotes chemical hepatocarcinogenesis: Role of oxidative stress and platelet-derived growth factor receptor alpha/phosphoinositide 3-kinase signaling. Hepatology, 2010, 52, 954-965.
    • (2010) Hepatology , vol.52 , pp. 954-965
    • Zhang, X.F.1    Tan, X.2    Zeng, G.3    Misse, A.4    Singh, S.5    Kim, Y.6    Klaunig, J.E.7    Monga, S.P.8
  • 58
    • 35348827355 scopus 로고    scopus 로고
    • Activation of the glutathione peroxidase 2 (GPx2) promoter by α-catenin
    • DOI 10.1515/BC.2007.137
    • Kipp, A.; Banning, A.; Brigelius-Flohe, R. Activation of the glutathione peroxidase 2 (GPx2) promoter by beta-catenin. Biol. Chem., 2007, 388, 1027-1033. (Pubitemid 47584311)
    • (2007) Biological Chemistry , vol.388 , Issue.10 , pp. 1027-1033
    • Kipp, A.1    Banning, A.2    Brigelius-Flohe, R.3
  • 60
    • 38649093310 scopus 로고    scopus 로고
    • Stabilization of α-catenin affects mouse embryonic liver growth and hepatoblast fate
    • DOI 10.1002/hep.21952
    • Decaens, T.; Godard, C.; de Reynies, A.; Rickman, D.S.; Tronche, F.; Couty, J.P.; Perret, C.; Colnot, S. Stabilization of beta-catenin affects mouse embryonic liver growth and hepatoblast fate. Hepatology, 2008, 47, 247-258. (Pubitemid 351171062)
    • (2008) Hepatology , vol.47 , Issue.1 , pp. 247-258
    • Decaens, T.1    Godard, C.2    De Reynies, A.3    Rickman, D.S.4    Tronche, F.5    Couty, J.-P.6    Perret, C.7    Colnot, S.8
  • 61
    • 35648988947 scopus 로고    scopus 로고
    • Adenomatous polyposis coli (APC): A multi-functional tumor suppressor gene
    • DOI 10.1242/jcs.03485
    • Aoki, K.; Taketo, M.M. Adenomatous polyposis coli (APC): A multi-functional tumor suppressor gene. J. Cell Sci., 2007, 120, 3327-3335. (Pubitemid 350028340)
    • (2007) Journal of Cell Science , vol.120 , Issue.19 , pp. 3327-3335
    • Aoki, K.1    Taketo, M.M.2
  • 62
    • 45849119423 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling in hepatic organogenesis
    • Nejak-Bowen, K.; Monga, S.P. Wnt/beta-catenin signaling in hepatic organogenesis. Organogenesis, 2008, 4, 92-99.
    • (2008) Organogenesis , vol.4 , pp. 92-99
    • Nejak-Bowen, K.1    Monga, S.P.2
  • 63
    • 0027466182 scopus 로고
    • 1,4-Bis[2-(3,5-dichloropyridyloxy)benzene, an extremely potent modulator of mouse hepatic cytochrome P-450 gene expression
    • Smith, G.; Henderson, C.J.; Parker, M.G.; White, R.; Bars, R.G.; Wolf, C.R. 1,4-Bis[2-(3,5-dichloropyridyloxy)]benzene, an extremely potent modulator of mouse hepatic cytochrome P-450 gene expression. Biochem. J., 1993, 289, 807-813. (Pubitemid 23074968)
    • (1993) Biochemical Journal , vol.289 , Issue.3 , pp. 807-813
    • Smith, G.1    Henderson, C.J.2    Parker, M.G.3    White, R.4    Bars, R.G.5    Wolf, C.R.6
  • 64
    • 0019176665 scopus 로고
    • 1,4-Bis[2-(3,5-dichloropyridyloxy)]benzene, a potent phenobarbital-like inducer of microsomal monooxygenase activity
    • Poland, A.; Mak, I.; Glover, E.; Boatman, R.J.; Ebetino, F.H.; Kende, A.S. 1,4-Bis[2-(3,5-dichloropyridyloxy)]benzene, a potent phenobarbital-like inducer of microsomal monooxygenase activity. Mol. Pharmacol., 1980, 18, 571-580. (Pubitemid 11205391)
    • (1980) Molecular Pharmacology , vol.18 , Issue.3 , pp. 571-580
    • Poland, A.1    Mak, I.2    Glover, E.3
  • 65
    • 0022244889 scopus 로고
    • 1,4-Bis[2-(3,5-dichloropyridyloxy)]benzene (TCPOBOP) and related compounds as inducers of hepatic monooxygenases. Structure-activity effects
    • DOI 10.1016/0006-2952(85)90722-1
    • Kelley, M.; Lambert, I.; Merrill, J.; Safe, S. 1,4-Bis[2-(3,5- dichloropyridyloxy)]benzene (TCPOBOP) and related compounds as inducers of hepatic monooxygenases. Structure-Activity effects. Biochem. Pharmacol., 1985, 34, 3489-3494. (Pubitemid 16252526)
    • (1985) Biochemical Pharmacology , vol.34 , Issue.19 , pp. 3489-3494
    • Kelley, M.1    Lambert, I.2    Merrill, J.3    Safe, S.4
  • 66
    • 0026779119 scopus 로고
    • P53 mutations are absent from carcinogen-induced mouse liver tumors but occur in cell lines established from these tumors
    • Kress, S.; Konig, J.; Schweizer, J.; Loehrke, H.; Bauer-Hofmann, R.; Schwarz, M. p53 mutations are absent from carcinogen-induced mouse liver tumors but occur in cell lines established from these tumors. Mol. Carcinogenesis, 1992, 6, 148-158.
    • (1992) Mol. Carcinogenesis , vol.6 , pp. 148-158
    • Kress, S.1    Konig, J.2    Schweizer, J.3    Loehrke, H.4    Bauer-Hofmann, R.5    Schwarz, M.6
  • 67
    • 13444304475 scopus 로고    scopus 로고
    • A α-catenin-dependent pathway regulates expression of cytochrome P450 isoforms in mouse liver tumors
    • DOI 10.1093/carcin/bgh298
    • Loeppen, S.; Koehle, C.; Buchmann, A.; Schwarz, M. A betacatenin- dependent pathway regulates expression of cytochrome P450 isoforms in mouse liver tumors. Carcinogenesis, 2005, 26, 239-248. (Pubitemid 40207719)
    • (2005) Carcinogenesis , vol.26 , Issue.1 , pp. 239-248
    • Loeppen, S.1    Koehle, C.2    Buchmann, A.3    Schwarz, M.4
  • 68
    • 0032830931 scopus 로고    scopus 로고
    • TCF transcription factors: Molecular switches in carcinogenesis
    • DOI 10.1016/S0304-419X(99)00026-8, PII S0304419X99000268
    • Roose, J.; Clevers, H. TCF transcription factors: Molecular switches in carcinogenesis. Biochim. Biophys. Acta, 1999, 1424, M23-37. (Pubitemid 29488713)
    • (1999) Biochimica et Biophysica Acta - Reviews on Cancer , vol.1424 , Issue.2-3
    • Roose, J.1    Clevers, H.2
  • 70
    • 0037369658 scopus 로고    scopus 로고
    • Overexpression of orphan G-protein-coupled receptor, Gpr49, in human hepatocellular carcinomas with α-catenin mutations
    • DOI 10.1053/jhep.2003.50029
    • Yamamoto, Y.; Sakamoto, M.; Fujii, G.; Tsuiji, H.; Kenetaka, K.; Asaka, M.; Hirohashi, S. Overexpression of orphan G-proteincoupled receptor, Gpr49, in human hepatocellular carcinomas with beta-catenin mutations. Hepatology, 2003, 37, 528-533. (Pubitemid 36258773)
    • (2003) Hepatology , vol.37 , Issue.3 , pp. 528-533
    • Yamamoto, Y.1    Sakamoto, M.2    Fujii, G.3    Tsuiji, H.4    Kanetaka, K.5    Asaka, M.6    Hirohashi, S.7
  • 71
    • 33748750533 scopus 로고    scopus 로고
    • The arylhydrocarbon receptor repressor (AhRR): Structure, expression, and function
    • DOI 10.1515/BC.2006.147, PII BCHM38791195
    • Haarmann-Stemmann, T.; Abel, J. The arylhydrocarbon receptor repressor (AhRR): Structure, expression, and function. Biol. Chem., 2006, 387, 1195-1199. (Pubitemid 44402065)
    • (2006) Biological Chemistry , vol.387 , Issue.9 , pp. 1195-1199
    • Haarmann-Stemmann, T.1    Abel, J.2
  • 72
    • 78649339242 scopus 로고    scopus 로고
    • An introduction to the molecular basics of aryl hydrocarbon receptor biology
    • Abel, J.; Haarmann-Stemmann, T. An introduction to the molecular basics of aryl hydrocarbon receptor biology. Biol. Chem., 2010, 391, 1235-1248.
    • (2010) Biol. Chem. , vol.391 , pp. 1235-1248
    • Abel, J.1    Haarmann-Stemmann, T.2
  • 73
    • 0028028534 scopus 로고
    • Aryl hydrocarbon or dioxin receptor: Biologic and toxic responses
    • Bock, K.W. Aryl hydrocarbon or dioxin receptor: Biologic and toxic responses. Rev. Physiol. Biochem. Pharmacol., 1994, 125, 1-42. (Pubitemid 2124701)
    • (1994) Rev. Physiol. Biochem. Pharmacol. , vol.125 , pp. 1-42
    • Bock, K.W.1
  • 75
    • 59149097955 scopus 로고    scopus 로고
    • AHR-dependent misregulation of Wnt signaling disrupts tissue regeneration
    • Mathew, L.K.; Simonich, M.T.; Tanguay, R.L. AHR-dependent misregulation of Wnt signaling disrupts tissue regeneration. Biochem. Pharmacol., 2009, 77, 498-507.
    • (2009) Biochem. Pharmacol. , vol.77 , pp. 498-507
    • Mathew, L.K.1    Simonich, M.T.2    Tanguay, R.L.3
  • 76
    • 48749116552 scopus 로고    scopus 로고
    • Crosstalk between AHR and Wnt signaling through RSpondin1 impairs tissue regeneration in zebrafish
    • Mathew, L.K.; Sengupta, S.S.; Ladu, J.; Andreasen, E.A.; Tanguay, R.L. Crosstalk between AHR and Wnt signaling through RSpondin1 impairs tissue regeneration in zebrafish. Faseb J., 2008, 22, 3087-3096.
    • (2008) Faseb J. , vol.22 , pp. 3087-3096
    • Mathew, L.K.1    Sengupta, S.S.2    Ladu, J.3    Andreasen, E.A.4    Tanguay, R.L.5
  • 77
    • 1942538298 scopus 로고    scopus 로고
    • Identification of Aryl Hydrocarbon Receptor as a Putative Wnt/α-Catenin Pathway Target Gene in Prostate Cancer Cells
    • DOI 10.1158/0008-5472.CAN-03-3309
    • Chesire, D.R.; Dunn, T.A.; Ewing, C.M.; Luo, J.; Isaacs, W.B. Identification of aryl hydrocarbon receptor as a putative Wnt/betacatenin pathway target gene in prostate cancer cells. Cancer Res., 2004, 64, 2523-2533. (Pubitemid 38523909)
    • (2004) Cancer Research , vol.64 , Issue.7 , pp. 2523-2533
    • Chesire, D.R.1    Dunn, T.A.2    Ewing, C.M.3    Luo, J.4    Isaacs, W.B.5
  • 78
    • 67650792459 scopus 로고    scopus 로고
    • The glycogen synthase kinase inhibitor SB216763 is a partial agonist of the aryl hydrocarbon receptor
    • Braeuning, A.; Buchmann, A. The glycogen synthase kinase inhibitor SB216763 is a partial agonist of the aryl hydrocarbon receptor. Drug Metab. Dispos., 2009, 37, 1576-1580.
    • (2009) Drug Metab. Dispos. , vol.37 , pp. 1576-1580
    • Braeuning, A.1    Buchmann, A.2
  • 80
    • 33750536032 scopus 로고    scopus 로고
    • Differential gene expression in periportal and perivenous mouse hepatocytes
    • DOI 10.1111/j.1742-4658.2006.05503.x
    • Braeuning, A.; Ittrich, C.; Kohle, C.; Hailfinger, S.; Bonin, M.; Buchmann, A.; Schwarz, M. Differential gene expression in periportal and perivenous mouse hepatocytes. Febs J., 2006, 273, 5051-5061. (Pubitemid 44673296)
    • (2006) FEBS Journal , vol.273 , Issue.22 , pp. 5051-5061
    • Braeuning, A.1    Ittrich, C.2    Kohle, C.3    Hailfinger, S.4    Bonin, M.5    Buchmann, A.6    Schwarz, M.7
  • 81
    • 33847749416 scopus 로고    scopus 로고
    • Liver-specific loss of α-catenin results in delayed hepatocyte proliferation after partial hepatectomy
    • DOI 10.1002/hep.21523
    • Sekine, S.; Gutierrez, P.J.; Lan, B.Y.; Feng, S.; Hebrok, M. Liverspecific loss of beta-catenin results in delayed hepatocyte proliferation after partial hepatectomy. Hepatology, 2007, 45, 361-368. (Pubitemid 46374592)
    • (2007) Hepatology , vol.45 , Issue.2 , pp. 361-368
    • Sekine, S.1    Gutierrez, P.J.A.2    Lan, B.Y.-A.3    Feng, S.4    Hebrok, M.5
  • 82
    • 0021223440 scopus 로고
    • 450-reductase, glutathione transferases and microsomal epoxide hydrolase
    • Wolf, C.R.; Moll, E.; Friedberg, T.; Oesch, F.; Buchmann, A.; Kuhlmann, W.D.; Kunz, H.W. Characterization, localization and regulation of a novel phenobarbital-inducible form of cytochrome P450, compared with three further P450-isoenzymes, NADPH P450-reductase, glutathione transferases and microsomal epoxide hydrolase. Carcinogenesis, 1984, 5, 993-1001. (Pubitemid 14061248)
    • (1984) Carcinogenesis , vol.5 , Issue.8 , pp. 993-1001
    • Wolf, C.R.1    Moll, E.2    Friedberg, T.3
  • 84
    • 28844439793 scopus 로고    scopus 로고
    • Interaction of nuclear receptors with the Wnt/α-catenin/Tcf signaling axis: Wnt you like to know?
    • DOI 10.1210/er.2003-0034
    • Mulholland, D.J.; Dedhar, S.; Coetzee, G.A.; Nelson, C.C. Interaction of nuclear receptors with the Wnt/beta-catenin/Tcf signaling axis: Wnt you like to know? Endocr. Rev., 2005, 26, 898-915. (Pubitemid 41770157)
    • (2005) Endocrine Reviews , vol.26 , Issue.7 , pp. 898-915
    • Mulholland, D.J.1    Dedhar, S.2    Coetzee, G.A.3    Nelson, C.C.4
  • 85
    • 0029986534 scopus 로고    scopus 로고
    • The aryl-hydrocarbon receptor, but not the arylhydrocarbon receptor nuclear translocator protein, is rapidly depleted in hepatic and nonhepatic culture cells exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin
    • Pollenz, R.S. The aryl-hydrocarbon receptor, but not the arylhydrocarbon receptor nuclear translocator protein, is rapidly depleted in hepatic and nonhepatic culture cells exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin. Mol. Pharmacol., 1996, 49, 391-398.
    • (1996) Mol. Pharmacol. , vol.49 , pp. 391-398
    • Pollenz, R.S.1
  • 86
    • 3042726385 scopus 로고    scopus 로고
    • CAR driving into the future
    • Swales, K.; Negishi, M. CAR, driving into the future. Mol. Endocrinol., 2004, 18, 1589-1598.
    • (2004) Mol. Endocrinol. , vol.18 , pp. 1589-1598
    • Swales, K.1    Negishi, M.2
  • 87
    • 23144447140 scopus 로고    scopus 로고
    • CAR, the continuously advancing receptor, in drug metabolism and disease
    • DOI 10.2174/1389200054633899
    • Qatanani, M.; Moore, D.D. CAR, the continuously advancing receptor, in drug metabolism and disease. Curr. Drug Metab., 2005, 6, 329-339. (Pubitemid 41086766)
    • (2005) Current Drug Metabolism , vol.6 , Issue.4 , pp. 329-339
    • Qatanani, M.1    Moore, D.D.2
  • 88
    • 80052466189 scopus 로고    scopus 로고
    • Gender-specific interplay of signaling through β-catenin and CAR in the regulation of xenobioticinduced hepatocyte proliferation
    • Braeuning, A., Heubach, Y., Knorpp, T., Kowalik, M.A., Templin, M., Columbano, A., Schwarz, M. Gender-specific interplay of signaling through β-catenin and CAR in the regulation of xenobioticinduced hepatocyte proliferation. Toxicol. Sci., 2011, 123, 113-122.
    • (2011) Toxicol. Sci. , vol.123 , pp. 113-122
    • Braeuning, A.1    Heubach, Y.2    Knorpp, T.3    Kowalik, M.A.4    Templin, M.5    Columbano, A.6    Schwarz, M.7
  • 89
    • 0029762765 scopus 로고    scopus 로고
    • Phenobarbital mechanistic data and risk assessment: Enzyme induction, enhanced cell proliferation, and tumor promotion
    • DOI 10.1016/0163-7258(96)00067-8
    • Whysner, J.; Ross, P.M.; Williams, G.M. Phenobarbital mechanistic data and risk assessment: Enzyme induction, enhanced cell proliferation, and tumor promotion. Pharmacol. Ther., 1996, 71, 153-191. (Pubitemid 26323295)
    • (1996) Pharmacology and Therapeutics , vol.71 , Issue.1-2 , pp. 153-191
    • Whysner, J.1    Ross, P.M.2    Williams, G.M.3
  • 90
    • 34247505536 scopus 로고    scopus 로고
    • Extracellular signal-regulated kinase is an endogenous signal retaining the nuclear Constitutive Active/androstane Receptor (CAR) in the cytoplasm of mouse primary hepatocytes
    • DOI 10.1124/mol.107.034538
    • Koike, C.; Moore, R.; Negishi, M. Extracellular signal-regulated kinase is an endogenous signal retaining the nuclear constitutive active/androstane receptor (CAR) in the cytoplasm of mouse primary hepatocytes. Mol. Pharmacol., 2007, 71, 1217-1221. (Pubitemid 46658675)
    • (2007) Molecular Pharmacology , vol.71 , Issue.5 , pp. 1217-1221
    • Koike, C.1    Moore, R.2    Negishi, M.3
  • 91
    • 34548458190 scopus 로고    scopus 로고
    • Serum components and activated Ha-ras antagonize expression of perivenous marker genes stimulated by α-catenin signaling in mouse hepatocytes
    • DOI 10.1111/j.1742-4658.2007.06002.x
    • Braeuning, A.; Menzel, M.; Kleinschnitz, E.M.; Harada, N.; Tamai, Y.; Kohle, C.; Buchmann, A.; Schwarz, M. Serum components and activated Ha-ras antagonize expression of perivenous marker genes stimulated by beta-catenin signaling in mouse hepatocytes. Febs J., 2007, 274, 4766-4777. (Pubitemid 47353126)
    • (2007) FEBS Journal , vol.274 , Issue.18 , pp. 4766-4777
    • Braeuning, A.1    Menzel, M.2    Kleinschnitz, E.-M.3    Harada, N.4    Tamai, Y.5    Kohle, C.6    Buchmann, A.7    Schwarz, M.8
  • 92
    • 43049101029 scopus 로고    scopus 로고
    • Dual-specificity MAP kinase phosphatases (MKPs) and cancer
    • Keyse, S.M. Dual-specificity MAP kinase phosphatases (MKPs) and cancer. Cancer Metastasis Rev., 2008, 27, 253-261.
    • (2008) Cancer Metastasis Rev. , vol.27 , pp. 253-261
    • Keyse, S.M.1
  • 93
    • 58849105030 scopus 로고    scopus 로고
    • A systems biological approach suggests that transcriptional feedback regulation by dual-specificity phosphatase 6 shapes extracellular signal-related kinase activity in RAS-transformed fibroblasts
    • Bluthgen, N.; Legewie, S.; Kielbasa, S.M.; Schramme, A.; Tchernitsa, O.; Keil, J.; Solf, A.; Vingron, M.; Schafer, R.; Herzel, H.; Sers, C. A systems biological approach suggests that transcriptional feedback regulation by dual-specificity phosphatase 6 shapes extracellular signal-related kinase activity in RAS-transformed fibroblasts. Febs J., 2009, 276, 1024-1035.
    • (2009) Febs J. , vol.276 , pp. 1024-1035
    • Bluthgen, N.1    Legewie, S.2    Kielbasa, S.M.3    Schramme, A.4    Tchernitsa, O.5    Keil, J.6    Solf, A.7    Vingron, M.8    Schafer, R.9    Herzel, H.10    Sers, C.11
  • 94
    • 67349237189 scopus 로고    scopus 로고
    • 2,2',4,4',5,5'-hexachlorobiphenyl (PCB 153) induces degradation of adherens junction proteins and inhibits beta-catenin-dependent transcription in liver epithelial cells
    • Simeckova, P.; Vondracek, J.; Prochazkova, J.; Kozubik, A.; Krcmar, P.; Machala, M. 2,2',4,4',5,5'-hexachlorobiphenyl (PCB 153) induces degradation of adherens junction proteins and inhibits beta-catenin-dependent transcription in liver epithelial cells. Toxicology, 2009, 260, 104-111.
    • (2009) Toxicology , vol.260 , pp. 104-111
    • Simeckova, P.1    Vondracek, J.2    Prochazkova, J.3    Kozubik, A.4    Krcmar, P.5    Machala, M.6
  • 95
    • 56649105360 scopus 로고    scopus 로고
    • Induction of hepatic glutathione S-transferases in male mice by prototypes of various classes of microsomal enzyme inducers
    • Knight, T.R.; Choudhuri, S.; Klaassen, C.D. Induction of hepatic glutathione S-transferases in male mice by prototypes of various classes of microsomal enzyme inducers. Toxicol. Sci., 2008, 106, 329-338.
    • (2008) Toxicol. Sci. , vol.106 , pp. 329-338
    • Knight, T.R.1    Choudhuri, S.2    Klaassen, C.D.3
  • 96
    • 0023264944 scopus 로고
    • Effects of retinoids on metabolizing enzymes and on binding of benzo(a)pyrene rat tissue DNA
    • McCarthy, D.J.; Lindamood, C.; Hill, D.L. Effects of retinoids on metabolizing enzymes and on binding of benzo(a)pyrene to rat tissue DNA. Cancer Res., 1987, 47, 5014-5020. (Pubitemid 17146465)
    • (1987) Cancer Research , vol.47 , Issue.19 , pp. 5014-5020
    • McCarthy, D.J.1    Lindamood III, C.2    Hill, D.L.3
  • 97
    • 0028017678 scopus 로고
    • The distribution of non-specific carboxylesterases and glutathione S-transferases in different rat liver cells. Effects of vitamin A deficiency
    • Gad, M.Z. The distribution of non-specific carboxylesterases and glutathione S-transferases in different rat liver cells. Effects of vitamin A deficiency. Biochem. Pharmacol., 1994, 48, 139-144.
    • (1994) Biochem. Pharmacol. , vol.48 , pp. 139-144
    • Gad, M.Z.1
  • 98
    • 0029015646 scopus 로고
    • Retinoids inhibit mammalian glutathione transferases
    • Kulkarni, A.A.; Kulkarni, A.P. Retinoids inhibit mammalian glutathione transferases. Cancer Lett., 1995, 91, 185-189.
    • (1995) Cancer Lett. , vol.91 , pp. 185-189
    • Kulkarni, A.A.1    Kulkarni, A.P.2
  • 99
    • 27844540822 scopus 로고    scopus 로고
    • Retinoid X receptor β regulates the expression of glutathione S-transferase genes and modulates acetaminophen-glutathione conjugation in mouse liver
    • DOI 10.1124/mol.105.013680
    • Dai, G.; Chou, N.; He, L.; Gyamfi, M.A.; Mendy, A.J.; Slitt, A.L.; Klaassen, C.D.; Wan, Y.J. Retinoid X receptor alpha Regulates the expression of glutathione s-transferase genes and modulates acetaminophen-glutathione conjugation in mouse liver. Mol. Pharmacol., 2005, 68, 1590-1596. (Pubitemid 41654343)
    • (2005) Molecular Pharmacology , vol.68 , Issue.6 , pp. 1590-1596
    • Dai, G.1    Chou, N.2    He, L.3    Gyamfi, M.A.4    Mendy, A.J.5    Slitt, A.L.6    Klaassen, C.D.7    Wan, Y.-J.Y.8
  • 101
    • 70349975929 scopus 로고    scopus 로고
    • Epigenetic modulation of the retinoid X receptor alpha by green tea in the azoxymethane-Apc Min/+ mouse model of intestinal cancer
    • Volate, S.R.; Muga, S.J.; Issa, A.Y.; Nitcheva, D.; Smith, T.; Wargovich, M.J. Epigenetic modulation of the retinoid X receptor alpha by green tea in the azoxymethane-Apc Min/+ mouse model of intestinal cancer. Mol. Carcinog., 2009, 48, 920-933.
    • (2009) Mol. Carcinog. , vol.48 , pp. 920-933
    • Volate, S.R.1    Muga, S.J.2    Issa, A.Y.3    Nitcheva, D.4    Smith, T.5    Wargovich, M.J.6
  • 102
    • 38849109982 scopus 로고    scopus 로고
    • Green tea polyphenols inhibit colorectal aberrant crypt foci (ACF) formation and prevent oncogenic changes in dysplastic ACF in azoxymethane-treated F344 rats
    • DOI 10.1093/carcin/bgm204
    • Xiao, H.; Hao, X.; Simi, B.; Ju, J.; Jiang, H.; Reddy, B.S.; Yang, C.S. Green tea polyphenols inhibit colorectal aberrant crypt foci (ACF) formation and prevent oncogenic changes in dysplastic ACF in azoxymethane-treated F344 rats. Carcinogenesis, 2008, 29, 113-119. (Pubitemid 351201749)
    • (2008) Carcinogenesis , vol.29 , Issue.1 , pp. 113-119
    • Xiao, H.1    Hao, X.2    Simi, B.3    Ju, J.4    Jiang, H.5    Reddy, B.S.6    Yang, C.S.7
  • 103
    • 0033518310 scopus 로고    scopus 로고
    • Crossregulation of beta-catenin-LEF/TCF and retinoid signaling pathways
    • Easwaran, V.; Pishvaian, M.; Salimuddin; Byers, S. Crossregulation of beta-catenin-LEF/TCF and retinoid signaling pathways. Curr. Biol., 1999, 9, 1415-1418.
    • (1999) Curr. Biol. , vol.9 , pp. 1415-1418
    • Easwaran, V.1    Pishvaian, M.2    Salimuddin3    Byers, S.4
  • 104
    • 0043032524 scopus 로고    scopus 로고
    • Adenomatous polyposis coli (APC)-independent regulation of α-catenin degradation via a retinoid X receptor-mediated pathway
    • DOI 10.1074/jbc.M304761200
    • Xiao, J.H.; Ghosn, C.; Hinchman, C.; Forbes, C.; Wang, J.; Snider, N.; Cordrey, A.; Zhao, Y.; Chandraratna, R.A. Adenomatous polyposis coli (APC)-independent regulation of beta-catenin degradation via a retinoid X receptor-mediated pathway. J. Biol. Chem., 2003, 278, 29954-29962. (Pubitemid 36962384)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.32 , pp. 29954-29962
    • Xiao, J.-H.1    Ghosn, C.2    Hinchman, C.3    Forbes, C.4    Wang, J.5    Snider, N.6    Cordrey, A.7    Zhao, Y.8    Chandraratna, R.A.S.9
  • 105
    • 33845442925 scopus 로고    scopus 로고
    • Mechanistic studies of the Nrf2-Keap1 signaling pathway
    • DOI 10.1080/03602530600971974, PII J6T0Q1874L787481
    • Zhang, D.D. Mechanistic studies of the Nrf2-Keap1 signaling pathway. Drug Metab. Rev., 2006, 38, 769-789. (Pubitemid 44903268)
    • (2006) Drug Metabolism Reviews , vol.38 , Issue.4 , pp. 769-789
    • Zhang, D.D.1
  • 106
    • 77649273272 scopus 로고    scopus 로고
    • Nrf2 the rescue: Effects of the antioxidative/electrophilic response on the liver
    • Klaassen, C.D.; Reisman, S.A. Nrf2 the rescue: Effects of the antioxidative/electrophilic response on the liver. Toxicol. Appl. Pharmacol., 2010, 244, 57-65.
    • (2010) Toxicol. Appl. Pharmacol. , vol.244 , pp. 57-65
    • Klaassen, C.D.1    Reisman, S.A.2
  • 107
    • 0037101768 scopus 로고    scopus 로고
    • Loss of the Nrf2 transcription factor causes a marked reduction in constitutive and inducible expression of the glutathione S-transferase Gsta1, Gsta2, Gstm1, Gstm2, Gstm3 and Gstm4 genes in the livers of male and female mice
    • DOI 10.1042/BJ20020320
    • Chanas, S.A.; Jiang, Q.; McMahon, M.; McWalter, G.K.; McLellan, L.I.; Elcombe, C.R.; Henderson, C.J.; Wolf, C.R.; Moffat, G.J.; Itoh, K.; Yamamoto, M.; Hayes, J.D. Loss of the Nrf2 transcription factor causes a marked reduction in constitutive and inducible expression of the glutathione S-transferase Gsta1, Gsta2, Gstm1, Gstm2, Gstm3 and Gstm4 genes in the livers of male and female mice. Biochem. J., 2002, 365, 405-416. (Pubitemid 36135312)
    • (2002) Biochemical Journal , vol.365 , Issue.2 , pp. 405-416
    • Chanas, S.A.1    Jiang, Q.2    McMahon, M.3    McWalter, G.K.4    McLellan, L.I.5    Elcombe, C.R.6    Henderson, C.J.7    Wolf, C.R.8    Moffat, G.J.9    Itoh, K.10    Yamamoto, M.11    Hayes, J.D.12
  • 108
    • 0032953192 scopus 로고    scopus 로고
    • Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain
    • Itoh, K.; Wakabayashi, N.; Katoh, Y.; Ishii, T.; Igarashi, K.; Engel, J.D.; Yamamoto, M. Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the aminoterminal Neh2 domain. Genes Dev., 1999, 13, 76-86. (Pubitemid 29045117)
    • (1999) Genes and Development , vol.13 , Issue.1 , pp. 76-86
    • Itoh, K.1    Wakabayashi, N.2    Katoh, Y.3    Ishii, T.4    Igarashi, K.5    Engel, J.D.6    Yamamoto, M.7
  • 109
    • 34447526197 scopus 로고    scopus 로고
    • GSK-3α acts upstream of Fyn kinase in regulation of nuclear export and degradation of NF-E2 related factor 2
    • DOI 10.1074/jbc.M611336200
    • Jain, A.K.; Jaiswal, A.K. GSK-3beta acts upstream of Fyn kinase in regulation of nuclear export and degradation of NF-E2 related factor 2. J. Biol. Chem., 2007, 282, 16502-16510. (Pubitemid 47100395)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.22 , pp. 16502-16510
    • Jain, A.K.1    Jaiswal, A.K.2
  • 110
    • 33744950387 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3α inhibits the xenobiotic and antioxidant cell response by direct phosphorylation and nuclear exclusion of the transcription factor Nrf2
    • DOI 10.1074/jbc.M513737200
    • Salazar, M.; Rojo, A.I.; Velasco, D.; de Sagarra, R.M.; Cuadrado, A. Glycogen synthase kinase-3beta inhibits the xenobiotic and antioxidant cell response by direct phosphorylation and nuclear exclusion of the transcription factor Nrf2. J. Biol. Chem., 2006, 281, 14841-14851. (Pubitemid 43855189)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.21 , pp. 14841-14851
    • Salazar, M.1    Rojo, A.I.2    Velasco, D.3    De Sagarra, R.M.4    Cuadrado, A.5
  • 111
    • 34447626493 scopus 로고    scopus 로고
    • Glycogen synthase kinase 3: A key regulator of cellular fate
    • DOI 10.1007/s00018-007-7045-7
    • Forde, J.E.; Dale, T.C. Glycogen synthase kinase 3: A key regulator of cellular fate. Cell. Mol. Life Sci., 2007, 64, 1930-1944. (Pubitemid 47094432)
    • (2007) Cellular and Molecular Life Sciences , vol.64 , Issue.15 , pp. 1930-1944
    • Forde, J.E.1    Dale, T.C.2
  • 112
    • 9944247695 scopus 로고    scopus 로고
    • Coordinate transcriptional regulation of bile acid homeostasis and drug metabolism
    • DOI 10.1016/j.abb.2004.09.019, PII S000398610400534X
    • Eloranta, J.J.; Kullak-Ublick, G.A. Coordinate transcriptional regulation of bile acid homeostasis and drug metabolism. Arch. Biochem. Biophys., 2005, 433, 397-412. (Pubitemid 39592794)
    • (2005) Archives of Biochemistry and Biophysics , vol.433 , Issue.2 , pp. 397-412
    • Eloranta, J.J.1    Kullak-Ublick, G.A.2
  • 113
    • 0036608007 scopus 로고    scopus 로고
    • Aroclor 1254 modulates gene expression of nuclear transcription factors: Implications for albumin gene transcription and protein synthesis in rat hepatocyte cultures
    • DOI 10.1006/taap.2002.9392
    • Borlak, J.; Dangers, M.; Thum, T. Aroclor 1254 modulates gene expression of nuclear transcription factors: Implications for albumin gene transcription and protein synthesis in rat hepatocyte cultures. Toxicol. Appl. Pharmacol., 2002, 181, 79-88. (Pubitemid 34625938)
    • (2002) Toxicology and Applied Pharmacology , vol.181 , Issue.2 , pp. 79-88
    • Borlak, J.1    Dangers, M.2    Thum, T.3
  • 114
    • 33645808917 scopus 로고    scopus 로고
    • Rifampicin induction of CYP3A4 requires pregnane X receptor cross talk with hepatocyte nuclear factor 4alpha and coactivators, and suppression of small heterodimer partner gene expression
    • Li, T.; Chiang, J.Y. Rifampicin induction of CYP3A4 requires pregnane X receptor cross talk with hepatocyte nuclear factor 4alpha and coactivators, and suppression of small heterodimer partner gene expression. Drug Metab. Dispos., 2006, 34, 756-764.
    • (2006) Drug Metab. Dispos. , vol.34 , pp. 756-764
    • Li, T.1    Chiang, J.Y.2
  • 116
    • 0030808426 scopus 로고    scopus 로고
    • Zonal distribution of transcripts of four hepatic transcription factors in the mature rat liver
    • DOI 10.1023/A:1007479223229
    • Lindros, K.O.; Oinonen, T.; Issakainen, J.; Nagy, P.; Thorgeirsson, S.S. Zonal distribution of transcripts of four hepatic transcription factors in the mature rat liver. Cell Biol. Toxicol., 1997, 13, 257-262. (Pubitemid 27373396)
    • (1997) Cell Biology and Toxicology , vol.13 , Issue.4-5 , pp. 257-262
    • Lindros, K.O.1    Oinonen, T.2    Issakainen, J.3    Nagy, P.4    Thorgeirsson, S.S.5


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