The v-Jun point mutation allows c-Jun to escape GSK3-dependent recognition and destruction by the Fbw7 ubiquitin ligase

Cancer Cell

Volumn 8, Issue 1, 2005, Pages 25-33

  Wei, Wenyi ^a   Jin, Jianping ^a   Schlisio, Susanne ^a   Harper, J Wade ^a   Kaelin Jr , William G ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOGEN SYNTHASE KINASE 3; GLYCOGEN SYNTHASE KINASE 3 INHIBITOR; PHENYLALANINE; PHOSPHOTHREONINE; PROTEASOME INHIBITOR; PROTEIN C JUN; SERINE; STRESS ACTIVATED PROTEIN KINASE INHIBITOR; TRANSCRIPTION FACTOR; UBIQUITIN PROTEIN LIGASE E3;

ARTICLE; BINDING AFFINITY; BINDING SITE; CARCINOGENICITY; CELL CYCLE; DOWN REGULATION; GENE MUTATION; HUMAN; MAMMAL CELL; NONHUMAN; ONCOGENE C MYC; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN STABILITY; REGULATORY MECHANISM;

MAMMALIA;

EID: 22244476115     PISSN: 15356108     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ccr.2005.06.005     Document Type: Article

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