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Volumn 29, Issue 2, 2004, Pages 95-102

The glamour and gloom of glycogen synthase kinase-3

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOGEN SYNTHASE KINASE 3;

EID: 0442276554     PISSN: 09680004     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tibs.2003.12.004     Document Type: Review
Times cited : (1386)

References (71)
  • 1
    • 0035983533 scopus 로고    scopus 로고
    • Alternative splicing isoform of tau protein kinase I/glycogen synthase kinase 3β
    • Mukai F., et al. Alternative splicing isoform of tau protein kinase I/glycogen synthase kinase 3β J. Neurochem. 81:2002;1073-1083.
    • (2002) J. Neurochem. , vol.81 , pp. 1073-1083
    • Mukai, F.1
  • 2
    • 0035477020 scopus 로고    scopus 로고
    • GSK3 takes centre stage more than 20 years after its discovery
    • Frame S., Cohen P. GSK3 takes centre stage more than 20 years after its discovery. Biochem. J. 359:2001;1-16.
    • (2001) Biochem. J. , vol.359 , pp. 1-16
    • Frame, S.1    Cohen, P.2
  • 3
    • 0037020072 scopus 로고    scopus 로고
    • A-kinase anchoring protein AKAP220 binds to glycogen synthase kinase-3β (GSK-3β) and mediates protein kinase A-dependent inhibition of GSK-3β
    • Tanji C., et al. A-kinase anchoring protein AKAP220 binds to glycogen synthase kinase-3β (GSK-3β) and mediates protein kinase A-dependent inhibition of GSK-3β J. Biol. Chem. 277:2002;36955-36961.
    • (2002) J. Biol. Chem. , vol.277 , pp. 36955-36961
    • Tanji, C.1
  • 4
    • 0034859101 scopus 로고    scopus 로고
    • The multifaceted roles of glycogen synthase kinase 3β in cellular signaling
    • Grimes C.A., Jope R.S. The multifaceted roles of glycogen synthase kinase 3β in cellular signaling. Prog. Neurobiol. 65:2001;391-426.
    • (2001) Prog. Neurobiol. , vol.65 , pp. 391-426
    • Grimes, C.A.1    Jope, R.S.2
  • 5
    • 0442290275 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3β is highly activated in nuclei and mitochondria
    • Bijur G.N., Jope R.S. Glycogen synthase kinase-3β is highly activated in nuclei and mitochondria. NeuroReport. 14:2003;2415-2419.
    • (2003) NeuroReport , vol.14 , pp. 2415-2419
    • Bijur, G.N.1    Jope, R.S.2
  • 6
    • 0032533225 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3β regulates cyclin D1 proteolysis and subcellular localization
    • Diehl J.A., et al. Glycogen synthase kinase-3β regulates cyclin D1 proteolysis and subcellular localization. Genes Dev. 12:1998;3499-3511.
    • (1998) Genes Dev. , vol.12 , pp. 3499-3511
    • Diehl, J.A.1
  • 7
    • 0035813212 scopus 로고    scopus 로고
    • Proapoptotic stimuli induce nuclear accumulation of glycogen synthase kinase-3β
    • Bijur G.N., Jope R.S. Proapoptotic stimuli induce nuclear accumulation of glycogen synthase kinase-3β J. Biol. Chem. 276:2001;37436-37442.
    • (2001) J. Biol. Chem. , vol.276 , pp. 37436-37442
    • Bijur, G.N.1    Jope, R.S.2
  • 8
    • 0346434149 scopus 로고    scopus 로고
    • Dynamic regulation of mitochondrial Akt and GSK3β
    • Bijur G.N., Jope R.S. Dynamic regulation of mitochondrial Akt and GSK3β J. Neurochem. 87:2003;1427-1435.
    • (2003) J. Neurochem. , vol.87 , pp. 1427-1435
    • Bijur, G.N.1    Jope, R.S.2
  • 9
    • 0036190970 scopus 로고    scopus 로고
    • Role of glycogen synthase kinase-3 in cancer: Regulation by Wnts and other signaling pathways
    • Manoukian A.S., Woodgett J.R. Role of glycogen synthase kinase-3 in cancer: regulation by Wnts and other signaling pathways. Adv. Cancer Res. 84:2002;203-229.
    • (2002) Adv. Cancer Res. , vol.84 , pp. 203-229
    • Manoukian, A.S.1    Woodgett, J.R.2
  • 10
    • 0037155737 scopus 로고    scopus 로고
    • Proteolysis of the hedgehog signaling effector cubitus interruptus requires phosphorylation by glycogen synthase kinase 3 and casein kinase 1
    • Price M.A., Kalderon D. Proteolysis of the hedgehog signaling effector cubitus interruptus requires phosphorylation by glycogen synthase kinase 3 and casein kinase 1. Cell. 108:2002;823-835.
    • (2002) Cell , vol.108 , pp. 823-835
    • Price, M.A.1    Kalderon, D.2
  • 11
    • 0037041470 scopus 로고    scopus 로고
    • Shaggy/GSK antagonizes hedgehog signaling by regulating cubitus interruptus
    • Jia J., et al. Shaggy/GSK antagonizes hedgehog signaling by regulating cubitus interruptus. Nature. 416:2002;548-552.
    • (2002) Nature , vol.416 , pp. 548-552
    • Jia, J.1
  • 12
    • 0037113982 scopus 로고    scopus 로고
    • The regulation of glycogen synthase kinase-3 nuclear export by Frat/GBP
    • Franca-Koh J., et al. The regulation of glycogen synthase kinase-3 nuclear export by Frat/GBP. J. Biol. Chem. 277:2002;43844-43848.
    • (2002) J. Biol. Chem. , vol.277 , pp. 43844-43848
    • Franca-Koh, J.1
  • 13
    • 0037062403 scopus 로고    scopus 로고
    • Direct, activating interaction between glycogen synthase kinase-3β and p53 after DNA damage
    • Watcharasit P., et al. Direct, activating interaction between glycogen synthase kinase-3β and p53 after DNA damage. Proc. Natl. Acad. Sci. U. S. A. 99:2002;7951-7955.
    • (2002) Proc. Natl. Acad. Sci. U. S. A. , vol.99 , pp. 7951-7955
    • Watcharasit, P.1
  • 14
    • 0037348372 scopus 로고    scopus 로고
    • A novel viral mechanism for dysregulation of β-catenin in Kaposi's sarcoma-associated herpesvirus latency
    • Fujimuro M., et al. A novel viral mechanism for dysregulation of β-catenin in Kaposi's sarcoma-associated herpesvirus latency. Nat. Med. 9:2003;300-306.
    • (2003) Nat. Med. , vol.9 , pp. 300-306
    • Fujimuro, M.1
  • 15
    • 0442274617 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3β (GSK3β) binds to, and promotes the actions of, p53
    • Watcharasit P., et al. Glycogen synthase kinase-3β (GSK3β) binds to, and promotes the actions of, p53. J. Biol. Chem. 278:2003;48872-48879.
    • (2003) J. Biol. Chem. , vol.278 , pp. 48872-48879
    • Watcharasit, P.1
  • 16
    • 0037434790 scopus 로고    scopus 로고
    • Cdc42 regulates GSK-3β and adenomatous polyposis coli to control cell polarity
    • Etienne-Manneville S., Hall A. Cdc42 regulates GSK-3β and adenomatous polyposis coli to control cell polarity. Nature. 421:2003;753-756.
    • (2003) Nature , vol.421 , pp. 753-756
    • Etienne-Manneville, S.1    Hall, A.2
  • 17
    • 0037092042 scopus 로고    scopus 로고
    • An inactive pool of GSK-3 at the leading edge of growth cones is implicated in semaphorin 3A signaling
    • Eickholt B.J., et al. An inactive pool of GSK-3 at the leading edge of growth cones is implicated in semaphorin 3A signaling. J. Cell Biol. 157:2002;211-217.
    • (2002) J. Cell Biol. , vol.157 , pp. 211-217
    • Eickholt, B.J.1
  • 18
    • 0031800971 scopus 로고    scopus 로고
    • Inhibition of GSK-3β leading to the loss of phosphorylated MAP-1B is an early event in axonal remodelling induced by WNT-7a or lithium
    • Lucas F.R., et al. Inhibition of GSK-3β leading to the loss of phosphorylated MAP-1B is an early event in axonal remodelling induced by WNT-7a or lithium. J. Cell Sci. 111:1998;1351-1361.
    • (1998) J. Cell Sci. , vol.111 , pp. 1351-1361
    • Lucas, F.R.1
  • 19
    • 0036311668 scopus 로고    scopus 로고
    • Valproate regulates GSK-3-mediated axonal remodeling and synapsin I clustering in developing neurons
    • Hall A.C., et al. Valproate regulates GSK-3-mediated axonal remodeling and synapsin I clustering in developing neurons. Mol. Cell. Neurosci. 20:2002;257-270.
    • (2002) Mol. Cell. Neurosci. , vol.20 , pp. 257-270
    • Hall, A.C.1
  • 20
    • 0037162094 scopus 로고    scopus 로고
    • Regulation of neuronal cytoskeleton by lysophosphatidic acid: Role of GSK-3
    • Sayas C.L., et al. Regulation of neuronal cytoskeleton by lysophosphatidic acid: role of GSK-3. Biochim. Biophys. Acta. 1582:2002;144-153.
    • (2002) Biochim. Biophys. Acta , vol.1582 , pp. 144-153
    • Sayas, C.L.1
  • 21
    • 0036469290 scopus 로고    scopus 로고
    • Glycogen synthase kinase 3 phosphorylates kinesin light chains and negatively regulates kinesin-based motility
    • Morfini G., et al. Glycogen synthase kinase 3 phosphorylates kinesin light chains and negatively regulates kinesin-based motility. EMBO J. 21:2002;281-293.
    • (2002) EMBO J. , vol.21 , pp. 281-293
    • Morfini, G.1
  • 22
    • 0037442990 scopus 로고    scopus 로고
    • A role for glycogen synthase kinase-3 in mitotic spindle dynamics and chromosome alignment
    • Wakefield J.G., et al. A role for glycogen synthase kinase-3 in mitotic spindle dynamics and chromosome alignment. J. Cell Sci. 116:2003;637-646.
    • (2003) J. Cell Sci. , vol.116 , pp. 637-646
    • Wakefield, J.G.1
  • 23
    • 0032493729 scopus 로고    scopus 로고
    • Role of glycogen synthase kinase-3 in the phosphatidylinositol 3-kinase/Akt cell survival pathway
    • Pap M., Cooper G.M. Role of glycogen synthase kinase-3 in the phosphatidylinositol 3-kinase/Akt cell survival pathway. J. Biol. Chem. 273:1998;19929-19932.
    • (1998) J. Biol. Chem. , vol.273 , pp. 19929-19932
    • Pap, M.1    Cooper, G.M.2
  • 24
    • 0036830441 scopus 로고    scopus 로고
    • Enhanced glycogen synthase kinase-3β activity mediates hypoxia-induced apoptosis of vascular smooth muscle cells and is prevented by glucose transport and metabolism
    • Loberg R.D., et al. Enhanced glycogen synthase kinase-3β activity mediates hypoxia-induced apoptosis of vascular smooth muscle cells and is prevented by glucose transport and metabolism. J. Biol. Chem. 277:2002;41667-41673.
    • (2002) J. Biol. Chem. , vol.277 , pp. 41667-41673
    • Loberg, R.D.1
  • 25
    • 0038292054 scopus 로고    scopus 로고
    • Prion peptide induces neuronal cell death through a pathway involving glycogen synthase kinase-3
    • Perez M., et al. Prion peptide induces neuronal cell death through a pathway involving glycogen synthase kinase-3. Biochem. J. 372:2003;129-136.
    • (2003) Biochem. J. , vol.372 , pp. 129-136
    • Perez, M.1
  • 26
    • 0037160134 scopus 로고    scopus 로고
    • Central role of glycogen synthase kinase-3β in endoplasmic reticulum stress-induced caspase-3 activation
    • Song L., et al. Central role of glycogen synthase kinase-3β in endoplasmic reticulum stress-induced caspase-3 activation. J. Biol. Chem. 277:2002;44701-44708.
    • (2002) J. Biol. Chem. , vol.277 , pp. 44701-44708
    • Song, L.1
  • 27
    • 0037072807 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3β inhibitors prevent cellular polyglutamine toxicity caused by the Huntington's disease mutation
    • Carmichael J., et al. Glycogen synthase kinase-3β inhibitors prevent cellular polyglutamine toxicity caused by the Huntington's disease mutation. J. Biol. Chem. 277:2002;33791-33798.
    • (2002) J. Biol. Chem. , vol.277 , pp. 33791-33798
    • Carmichael, J.1
  • 28
    • 0036829025 scopus 로고    scopus 로고
    • Regulation of angiogenesis by glycogen synthase kinase-3β
    • Kim H.S., et al. Regulation of angiogenesis by glycogen synthase kinase-3β J. Biol. Chem. 277:2002;41888-41896.
    • (2002) J. Biol. Chem. , vol.277 , pp. 41888-41896
    • Kim, H.S.1
  • 29
    • 0029776032 scopus 로고    scopus 로고
    • A molecular mechanism for the effect of lithium on development
    • Klein P.S., Melton D.A. A molecular mechanism for the effect of lithium on development. Proc. Natl. Acad. Sci. U. S. A. 93:1996;8455-8459.
    • (1996) Proc. Natl. Acad. Sci. U. S. A. , vol.93 , pp. 8455-8459
    • Klein, P.S.1    Melton, D.A.2
  • 30
    • 0036116367 scopus 로고    scopus 로고
    • Neuroprotective effects of lithium in cultured cells and animal models of diseases
    • Chuang D.M., et al. Neuroprotective effects of lithium in cultured cells and animal models of diseases. Bipolar Disord. 4:2002;129-136.
    • (2002) Bipolar Disord. , vol.4 , pp. 129-136
    • Chuang, D.M.1
  • 31
    • 0034677804 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3β facilitates staurosporine- and heat shock-induced apoptosis: Protection by lithium
    • Bijur G.N., et al. Glycogen synthase kinase-3β facilitates staurosporine- and heat shock-induced apoptosis: protection by lithium. J. Biol. Chem. 275:2000;7583-7590.
    • (2000) J. Biol. Chem. , vol.275 , pp. 7583-7590
    • Bijur, G.N.1
  • 32
    • 0036103182 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3β, mood stabilizers, and neuroprotection
    • Li X., et al. Glycogen synthase kinase-3β, mood stabilizers, and neuroprotection. Bipolar Disord. 4:2002;137-144.
    • (2002) Bipolar Disord. , vol.4 , pp. 137-144
    • Li, X.1
  • 33
    • 0035087123 scopus 로고    scopus 로고
    • Selective small-molecule inhibitors of glycogen synthase kinase-3 activity protect primary neurones from death
    • Cross D.A., et al. Selective small-molecule inhibitors of glycogen synthase kinase-3 activity protect primary neurones from death. J. Neurochem. 77:2001;94-102.
    • (2001) J. Neurochem. , vol.77 , pp. 94-102
    • Cross, D.A.1
  • 34
    • 0036136897 scopus 로고    scopus 로고
    • Role of translation initiation factor 2B in control of cell survival by the phosphatidylinositol 3-kinase/Akt/glycogen synthase kinase 3β signaling pathway
    • Pap M., Cooper G.M. Role of translation initiation factor 2B in control of cell survival by the phosphatidylinositol 3-kinase/Akt/glycogen synthase kinase 3β signaling pathway. Mol. Cell. Biol. 22:2002;578-586.
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 578-586
    • Pap, M.1    Cooper, G.M.2
  • 35
    • 0037853146 scopus 로고    scopus 로고
    • Glycogen synthase kinase 3β is a natural activator of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase kinase 1 (MEKK1)
    • Kim J.W., et al. Glycogen synthase kinase 3β is a natural activator of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase kinase 1 (MEKK1). J. Biol. Chem. 278:2003;13995-14001.
    • (2003) J. Biol. Chem. , vol.278 , pp. 13995-14001
    • Kim, J.W.1
  • 36
    • 0042971809 scopus 로고    scopus 로고
    • Lithium blocks the c-Jun stress response and protects neurons via its action on glycogen synthase kinase 3
    • Hongisto V., et al. Lithium blocks the c-Jun stress response and protects neurons via its action on glycogen synthase kinase 3. Mol. Cell. Biol. 23:2003;6027-6036.
    • (2003) Mol. Cell. Biol. , vol.23 , pp. 6027-6036
    • Hongisto, V.1
  • 37
    • 0034612636 scopus 로고    scopus 로고
    • Requirement for glycogen synthase kinase-3β in cell survival and NF-κB activation
    • Hoeflich K.P., et al. Requirement for glycogen synthase kinase-3β in cell survival and NF-κB activation. Nature. 406:2000;86-90.
    • (2000) Nature , vol.406 , pp. 86-90
    • Hoeflich, K.P.1
  • 38
    • 0035854706 scopus 로고    scopus 로고
    • Lithium sensitizes tumor cells in an NF-κB-independent way to caspase activation and apoptosis induced by tumor necrosis factor (TNF)
    • Schotte P., et al. Lithium sensitizes tumor cells in an NF-κB-independent way to caspase activation and apoptosis induced by tumor necrosis factor (TNF). J. Biol. Chem. 276:2001;25939-25945.
    • (2001) J. Biol. Chem. , vol.276 , pp. 25939-25945
    • Schotte, P.1
  • 39
    • 0036081578 scopus 로고    scopus 로고
    • Role of glycogen synthase kinase-3 in TNF-α-induced NF-κB activation and apoptosis in hepatocytes
    • Schwabe R.F., Brenner D.A. Role of glycogen synthase kinase-3 in TNF-α-induced NF-κB activation and apoptosis in hepatocytes. Am. J. Physiol. Gastrointest. Liver Physiol. 283:2002;G204-G211.
    • (2002) Am. J. Physiol. Gastrointest. Liver Physiol. , vol.283
    • Schwabe, R.F.1    Brenner, D.A.2
  • 40
    • 0141928780 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3β regulates NF-κB1/p105 stability
    • Demarchi F., et al. Glycogen synthase kinase-3β regulates NF-κB1/p105 stability. J. Biol. Chem. 278:2003;39583-39590.
    • (2003) J. Biol. Chem. , vol.278 , pp. 39583-39590
    • Demarchi, F.1
  • 41
    • 0036903270 scopus 로고    scopus 로고
    • Functional gene screening in embryonic stem cells implicates Wnt antagonism in neural differentiation
    • Aubert J., et al. Functional gene screening in embryonic stem cells implicates Wnt antagonism in neural differentiation. Nat. Biotechnol. 20:2002;1240-1245.
    • (2002) Nat. Biotechnol. , vol.20 , pp. 1240-1245
    • Aubert, J.1
  • 42
    • 0037596751 scopus 로고    scopus 로고
    • Synthetic small molecules that control stem cell fate
    • Ding S., et al. Synthetic small molecules that control stem cell fate. Proc. Natl. Acad. Sci. U. S. A. 100:2003;7632-7637.
    • (2003) Proc. Natl. Acad. Sci. U. S. A. , vol.100 , pp. 7632-7637
    • Ding, S.1
  • 43
    • 0037205315 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3β: A novel regulator of cardiac hypertrophy and development
    • Hardt S.E., Sadoshima J. Glycogen synthase kinase-3β: a novel regulator of cardiac hypertrophy and development. Circ. Res. 90:2002;1055-1063.
    • (2002) Circ. Res. , vol.90 , pp. 1055-1063
    • Hardt, S.E.1    Sadoshima, J.2
  • 44
    • 0037446892 scopus 로고    scopus 로고
    • Stabilization of β-catenin by a Wnt-independent mechanism regulates cardiomyocyte growth
    • Haq S., et al. Stabilization of β-catenin by a Wnt-independent mechanism regulates cardiomyocyte growth. Proc. Natl. Acad. Sci. U. S. A. 100:2003;4610-4615.
    • (2003) Proc. Natl. Acad. Sci. U. S. A. , vol.100 , pp. 4610-4615
    • Haq, S.1
  • 45
    • 0035990924 scopus 로고    scopus 로고
    • Inhibition of protein kinase B/Akt. Implications for cancer therapy
    • Hill M.M., Hemmings B.A. Inhibition of protein kinase B/Akt. Implications for cancer therapy. Pharmacol. Ther. 93:2002;243-251.
    • (2002) Pharmacol. Ther. , vol.93 , pp. 243-251
    • Hill, M.M.1    Hemmings, B.A.2
  • 46
    • 0032947795 scopus 로고    scopus 로고
    • Anti-bipolar therapy: Mechanism of action of lithium
    • Jope R.S. Anti-bipolar therapy: mechanism of action of lithium. Mol. Psychiatry. 4:1999;117-128.
    • (1999) Mol. Psychiatry , vol.4 , pp. 117-128
    • Jope, R.S.1
  • 48
    • 0036154321 scopus 로고    scopus 로고
    • GSK-3 and the neurodevelopmental hypothesis of schizophrenia
    • Kozlovsky N., et al. GSK-3 and the neurodevelopmental hypothesis of schizophrenia. Eur. Neuropsychopharmacol. 12:2002;13-25.
    • (2002) Eur. Neuropsychopharmacol. , vol.12 , pp. 13-25
    • Kozlovsky, N.1
  • 49
    • 0036090823 scopus 로고    scopus 로고
    • Glycogen synthase kinase 3: An emerging therapeutic target
    • Eldar-Finkelman H. Glycogen synthase kinase 3: an emerging therapeutic target. Trends Mol. Med. 8:2002;126-132.
    • (2002) Trends Mol. Med. , vol.8 , pp. 126-132
    • Eldar-Finkelman, H.1
  • 50
    • 0033958644 scopus 로고    scopus 로고
    • Potential role of glycogen synthase kinase-3 in skeletal muscle insulin resistance of type 2 diabetes
    • Nikoulina S.E., et al. Potential role of glycogen synthase kinase-3 in skeletal muscle insulin resistance of type 2 diabetes. Diabetes. 49:2000;263-271.
    • (2000) Diabetes , vol.49 , pp. 263-271
    • Nikoulina, S.E.1
  • 51
    • 0035038729 scopus 로고    scopus 로고
    • Inhibition of GSK-3 selectively reduces glucose-6-phosphatase and phosphatase and phosphoenolypyruvate carboxykinase gene expression
    • Lochhead P.A., et al. Inhibition of GSK-3 selectively reduces glucose-6-phosphatase and phosphatase and phosphoenolypyruvate carboxykinase gene expression. Diabetes. 50:2001;937-946.
    • (2001) Diabetes , vol.50 , pp. 937-946
    • Lochhead, P.A.1
  • 52
    • 0033776383 scopus 로고    scopus 로고
    • Selective small molecule inhibitors of glycogen synthase kinase-3 modulate glycogen metabolism and gene transcription
    • Coghlan M.P., et al. Selective small molecule inhibitors of glycogen synthase kinase-3 modulate glycogen metabolism and gene transcription. Chem. Biol. 7:2000;793-803.
    • (2000) Chem. Biol. , vol.7 , pp. 793-803
    • Coghlan, M.P.1
  • 53
    • 0141558915 scopus 로고    scopus 로고
    • Use of lithium and SB-415286 to explore the role of glycogen synthase kinase-3 in the regulation of glucose transport and glycogen synthase
    • MacAulay K., et al. Use of lithium and SB-415286 to explore the role of glycogen synthase kinase-3 in the regulation of glucose transport and glycogen synthase. Eur. J. Biochem. 270:2003;3829-3838.
    • (2003) Eur. J. Biochem. , vol.270 , pp. 3829-3838
    • MacAulay, K.1
  • 54
    • 0038811796 scopus 로고    scopus 로고
    • Insulin mimetic action of synthetic phosphorylated peptide inhibitors of glycogen synthase kinase-3
    • Plotkin B., et al. Insulin mimetic action of synthetic phosphorylated peptide inhibitors of glycogen synthase kinase-3. J. Pharmacol. Exp. Ther. 305:2003;974-980.
    • (2003) J. Pharmacol. Exp. Ther. , vol.305 , pp. 974-980
    • Plotkin, B.1
  • 55
    • 0037339766 scopus 로고    scopus 로고
    • Selective glycogen synthase kinase 3 inhibitors potentiate insulin activation of glucose transport and utilization in vitro and in vivo
    • Ring D.B., et al. Selective glycogen synthase kinase 3 inhibitors potentiate insulin activation of glucose transport and utilization in vitro and in vivo. Diabetes. 52:2003;588-595.
    • (2003) Diabetes , vol.52 , pp. 588-595
    • Ring, D.B.1
  • 56
    • 0037405647 scopus 로고    scopus 로고
    • Modulation of muscle insulin resistance by selective inhibition of GSK-3 in Zucker diabetic fatty rats
    • Henriksen E.J., et al. Modulation of muscle insulin resistance by selective inhibition of GSK-3 in Zucker diabetic fatty rats. Am. J. Physiol. Endocrinol. Metab. 284:2003;E892-E900.
    • (2003) Am. J. Physiol. Endocrinol. Metab. , vol.284
    • Henriksen, E.J.1
  • 57
    • 0036302960 scopus 로고    scopus 로고
    • Inhibition of glycogen synthase kinase 3 improves insulin action and glucose metabolism in human skeletal muscle
    • Nikoulina S.E., et al. Inhibition of glycogen synthase kinase 3 improves insulin action and glucose metabolism in human skeletal muscle. Diabetes. 51:2002;2190-2198.
    • (2002) Diabetes , vol.51 , pp. 2190-2198
    • Nikoulina, S.E.1
  • 58
    • 0038187674 scopus 로고    scopus 로고
    • GSK-3α regulates production of Alzheimer's disease amyloid-β peptides
    • Phiel C.J., et al. GSK-3α regulates production of Alzheimer's disease amyloid-β peptides. Nature. 423:2003;435-439.
    • (2003) Nature , vol.423 , pp. 435-439
    • Phiel, C.J.1
  • 59
    • 0033151570 scopus 로고    scopus 로고
    • Presenilin 1 facilitates the constitutive turnover of β-catenin: Differential activity of Alzheimer's disease-linked PS1 mutants in the β-catenin signaling pathway
    • Kang D.E., et al. Presenilin 1 facilitates the constitutive turnover of β-catenin: differential activity of Alzheimer's disease-linked PS1 mutants in the β-catenin signaling pathway. J. Neurosci. 19:1999;4229-4237.
    • (1999) J. Neurosci. , vol.19 , pp. 4229-4237
    • Kang, D.E.1
  • 60
    • 0035914322 scopus 로고    scopus 로고
    • Presenilin 1 regulates β-catenin-mediated transcription in a glycogen synthase kinase-3-independent fashion
    • Palacino J.J., et al. Presenilin 1 regulates β-catenin-mediated transcription in a glycogen synthase kinase-3-independent fashion. J. Biol. Chem. 276:2001;38563-38569.
    • (2001) J. Biol. Chem. , vol.276 , pp. 38563-38569
    • Palacino, J.J.1
  • 61
    • 0038118207 scopus 로고    scopus 로고
    • Alzheimer's presenilin 1 mutations impair kinesin-based axonal transport
    • Pigino G., et al. Alzheimer's presenilin 1 mutations impair kinesin-based axonal transport. J. Neurosci. 23:2003;4499-4508.
    • (2003) J. Neurosci. , vol.23 , pp. 4499-4508
    • Pigino, G.1
  • 62
    • 0037414833 scopus 로고    scopus 로고
    • Glycogen synthase kinase 3β phosphorylates tau at both primed and unprimed sites: Differential impact on microtubule binding
    • Cho J.-H., Johnson G.V.W. Glycogen synthase kinase 3β phosphorylates tau at both primed and unprimed sites: differential impact on microtubule binding. J. Biol. Chem. 278:2003;187-193.
    • (2003) J. Biol. Chem. , vol.278 , pp. 187-193
    • Cho, J.-H.1    Johnson, G.V.W.2
  • 63
    • 0034969088 scopus 로고    scopus 로고
    • A common phosphate binding site explains the unique substrate specificity of GSK3 and its inactivation by phosphorylation
    • Frame S., et al. A common phosphate binding site explains the unique substrate specificity of GSK3 and its inactivation by phosphorylation. Mol. Cell. 7:2001;1321-1327.
    • (2001) Mol. Cell , vol.7 , pp. 1321-1327
    • Frame, S.1
  • 64
    • 0035875098 scopus 로고    scopus 로고
    • Crystal structure of glycogen synthase kinase 3β: Structural basis for phosphate-primed substrate specificity and autoinhibition
    • Dajani R., et al. Crystal structure of glycogen synthase kinase 3β: structural basis for phosphate-primed substrate specificity and autoinhibition. Cell. 105:2001;721-732.
    • (2001) Cell , vol.105 , pp. 721-732
    • Dajani, R.1
  • 65
    • 0036226855 scopus 로고    scopus 로고
    • Identification of a link between the tumour suppressor APC and the kinesin superfamily
    • Jimbo T., et al. Identification of a link between the tumour suppressor APC and the kinesin superfamily. Nat. Cell Biol. 4:2002;323-327.
    • (2002) Nat. Cell Biol. , vol.4 , pp. 323-327
    • Jimbo, T.1
  • 67
    • 0036942843 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3 is associated with neuronal and glial hyperphosphorylated tau deposits in Alzheimer's disease, Pick's disease, progressive supranuclear palsy and corticobasal degeneration
    • Ferrer I., et al. Glycogen synthase kinase-3 is associated with neuronal and glial hyperphosphorylated tau deposits in Alzheimer's disease, Pick's disease, progressive supranuclear palsy and corticobasal degeneration. Acta Neuropathol. (Berl.). 104:2002;583-591.
    • (2002) Acta Neuropathol. (Berl.) , vol.104 , pp. 583-591
    • Ferrer, I.1
  • 68
    • 1642363745 scopus 로고    scopus 로고
    • Spatial learning deficit in transgenic mice that conditionally over-express GSK-3β in the brain but do not form tau filaments
    • Hernandez F., et al. Spatial learning deficit in transgenic mice that conditionally over-express GSK-3β in the brain but do not form tau filaments. J. Neurochem. 83:2002;1529-1533.
    • (2002) J. Neurochem. , vol.83 , pp. 1529-1533
    • Hernandez, F.1
  • 69
    • 0034731461 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3β phosphorylates protein tau and rescues the axonopathy in the central nervous system of human four-repeat tau transgenic mice
    • Spittaels K., et al. Glycogen synthase kinase-3β phosphorylates protein tau and rescues the axonopathy in the central nervous system of human four-repeat tau transgenic mice. J. Biol. Chem. 275:2000;41340-41349.
    • (2000) J. Biol. Chem. , vol.275 , pp. 41340-41349
    • Spittaels, K.1
  • 70
    • 0037087220 scopus 로고    scopus 로고
    • Lithium inhibits amyloid secretion in COS7 cells transfected with amyloid precursor protein C100
    • Sun X., et al. Lithium inhibits amyloid secretion in COS7 cells transfected with amyloid precursor protein C100. Neurosci. Lett. 321:2002;61-64.
    • (2002) Neurosci. Lett. , vol.321 , pp. 61-64
    • Sun, X.1
  • 71
    • 0036942638 scopus 로고    scopus 로고
    • The active form of glycogen synthase kinase-3β is associated with granulovacuolar degeneration in neurons in Alzheimer's disease
    • Leroy K., et al. The active form of glycogen synthase kinase-3β is associated with granulovacuolar degeneration in neurons in Alzheimer's disease. Acta Neuropathol. (Berl.). 103:2002;91-99.
    • (2002) Acta Neuropathol. (Berl.) , vol.103 , pp. 91-99
    • Leroy, K.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.