메뉴 건너뛰기




Volumn 48, Issue 4, 2008, Pages 1302-1311

c-Myc and its target foxM1 are critical downstream effectors of constitutive androstane receptor (CAR) mediated direct liver hyperplasia

Author keywords

[No Author keywords available]

Indexed keywords

1,4 BIS(3,5 DICHLORO 2 PYRIDYLOXY)BENZENE; CELL CYCLE PROTEIN; CELL CYCLE PROTEIN 20; CONSTITUTIVE ANDROSTANE RECEPTOR; CYCLIN DEPENDENT KINASE 1; CYCLINE; MINICHROMOSOME MAINTENANCE PROTEIN; MUTANT PROTEIN; MYC PROTEIN; TRANSCRIPTION FACTOR FOXM1; UNCLASSIFIED DRUG; 1,4 BIS(2 (3,5 DICHLOROPYRIDYLOXY))BENZENE; 1,4-BIS(2-(3,5-DICHLOROPYRIDYLOXY))BENZENE; CELL RECEPTOR; FORKHEAD TRANSCRIPTION FACTOR; FOXM1 PROTEIN, MOUSE; MYC PROTEIN, MOUSE; PYRIDINE DERIVATIVE; TRANSCRIPTION FACTOR;

EID: 54449087431     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1002/hep.22475     Document Type: Article
Times cited : (115)

References (45)
  • 1
    • 0032901285 scopus 로고    scopus 로고
    • Cytochrome P450-based cancer gene therapy: Recent advances and future prospects
    • Waxman DJ, Chen L, Hecht JE, Jounaidi Y. Cytochrome P450-based cancer gene therapy: Recent advances and future prospects. Drug Metab Rev 1999;31:503-522.
    • (1999) Drug Metab Rev , vol.31 , pp. 503-522
    • Waxman, D.J.1    Chen, L.2    Hecht, J.E.3    Jounaidi, Y.4
  • 2
    • 0034687397 scopus 로고    scopus 로고
    • The nuclear receptor CAR mediates specific xenobiotic induction of drug metabolism
    • Wei P, Zhang J, Egan-Hafley M, Liang S, Moore DD. The nuclear receptor CAR mediates specific xenobiotic induction of drug metabolism. Nature 2000;407:920-923.
    • (2000) Nature , vol.407 , pp. 920-923
    • Wei, P.1    Zhang, J.2    Egan-Hafley, M.3    Liang, S.4    Moore, D.D.5
  • 3
    • 0033199499 scopus 로고    scopus 로고
    • P450 gene induction by structurally diverse xenochemicals: Central role of nuclear receptors CAR, PXR, and PPAR
    • Waxman DJ. P450 gene induction by structurally diverse xenochemicals: central role of nuclear receptors CAR, PXR, and PPAR. Arch Biochem Biophys 1999;369:11-23.
    • (1999) Arch Biochem Biophys , vol.369 , pp. 11-23
    • Waxman, D.J.1
  • 4
    • 23144447140 scopus 로고    scopus 로고
    • CAR, the continuously advancing receptor, in drug metabolism and disease
    • Qatanani M, Moore DD. CAR, the continuously advancing receptor, in drug metabolism and disease. Curr Drug Metab 2005;6:329-339.
    • (2005) Curr Drug Metab , vol.6 , pp. 329-339
    • Qatanani, M.1    Moore, D.D.2
  • 5
    • 0026739340 scopus 로고
    • Tumor-promoting and hepatocarcinogenic effects of 1,4-bis[2-(3,5-dichloropyridyloxy)]benzene (TCPOBOP) in DBA/2NCr and C57BL/6NCr mice and an apparent promoting effect on nasal cavity tumors but not on hepatocellular tumors in F344/ NCr rats initiated with N-nitrosodiethylamine
    • Diwan BA, Lubet RA, Ward JM, Hrabie JA, Rice JM. Tumor-promoting and hepatocarcinogenic effects of 1,4-bis[2-(3,5-dichloropyridyloxy)]benzene (TCPOBOP) in DBA/2NCr and C57BL/6NCr mice and an apparent promoting effect on nasal cavity tumors but not on hepatocellular tumors in F344/ NCr rats initiated with N-nitrosodiethylamine. Carcinogenesis 1992;13:1893-1901.
    • (1992) Carcinogenesis , vol.13 , pp. 1893-1901
    • Diwan, B.A.1    Lubet, R.A.2    Ward, J.M.3    Hrabie, J.A.4    Rice, J.M.5
  • 6
    • 0043268127 scopus 로고    scopus 로고
    • A common set of immediate-early response genes in liver regeneration and hyperplasia
    • Locker J, Tian J, Carver R, Concas D, Cossu C, Ledda-Columbano GM, et al. A common set of immediate-early response genes in liver regeneration and hyperplasia. HEPATOLOGY 2003;38:314-325.
    • (2003) HEPATOLOGY , vol.38 , pp. 314-325
    • Locker, J.1    Tian, J.2    Carver, R.3    Concas, D.4    Cossu, C.5    Ledda-Columbano, G.M.6
  • 7
    • 30944440962 scopus 로고    scopus 로고
    • The CAR nuclear receptor and hepatocyte proliferation
    • Costa RH, Kalinichenko VV, Tan Y, Wang IC. The CAR nuclear receptor and hepatocyte proliferation. HEPATOLOGY 2005;42:1004-1008.
    • (2005) HEPATOLOGY , vol.42 , pp. 1004-1008
    • Costa, R.H.1    Kalinichenko, V.V.2    Tan, Y.3    Wang, I.C.4
  • 8
    • 22344451423 scopus 로고    scopus 로고
    • Xenobiotic stress induces hepatomegaly and liver tumors via the nuclear receptor constitutive androstane receptor
    • Huang W, Zhang J, Washington M, Liu J, Parant JM, Lozano G, et al. Xenobiotic stress induces hepatomegaly and liver tumors via the nuclear receptor constitutive androstane receptor. Mol Endocrinol 2005;19:1646-1653.
    • (2005) Mol Endocrinol , vol.19 , pp. 1646-1653
    • Huang, W.1    Zhang, J.2    Washington, M.3    Liu, J.4    Parant, J.M.5    Lozano, G.6
  • 9
    • 0036829767 scopus 로고    scopus 로고
    • Loss of cyclin D1 does not inhibit the proliferative response of mouse liver to mitogenic stimuli
    • Ledda-Columbano GM, Pibiri M, Concas D, Cossu C, Tripodi M, Columbano A. Loss of cyclin D1 does not inhibit the proliferative response of mouse liver to mitogenic stimuli. HEPATOLOGY 2002;36:1098-1105.
    • (2002) HEPATOLOGY , vol.36 , pp. 1098-1105
    • Ledda-Columbano, G.M.1    Pibiri, M.2    Concas, D.3    Cossu, C.4    Tripodi, M.5    Columbano, A.6
  • 10
    • 4644333017 scopus 로고    scopus 로고
    • Aging does not reduce the hepatocyte proliferative response of mice to the primary mitogen TCPOBOP
    • Ledda-Columbano GM, Pibiri M, Cossu C, Molotzu F, Locker J, Columbano A. Aging does not reduce the hepatocyte proliferative response of mice to the primary mitogen TCPOBOP. HEPATOLOGY 2004;40:981-988.
    • (2004) HEPATOLOGY , vol.40 , pp. 981-988
    • Ledda-Columbano, G.M.1    Pibiri, M.2    Cossu, C.3    Molotzu, F.4    Locker, J.5    Columbano, A.6
  • 14
    • 7744220635 scopus 로고    scopus 로고
    • MYC inactivation uncovers pluripotent differentiation and tumour dormancy in hepatocellular cancer
    • Shachaf CM, Kopelman AM, Arvanitis C, Karlsson A, Beer S, Mandl S, et al. MYC inactivation uncovers pluripotent differentiation and tumour dormancy in hepatocellular cancer. Nature 2004;431:1112-1117.
    • (2004) Nature , vol.431 , pp. 1112-1117
    • Shachaf, C.M.1    Kopelman, A.M.2    Arvanitis, C.3    Karlsson, A.4    Beer, S.5    Mandl, S.6
  • 15
    • 14744305803 scopus 로고    scopus 로고
    • More than just proliferation: Myc function in stem cells
    • Murphy MJ, Wilson A, Trumpp A. More than just proliferation: Myc function in stem cells. Trends Cell Biol 2005;15:128-137.
    • (2005) Trends Cell Biol , vol.15 , pp. 128-137
    • Murphy, M.J.1    Wilson, A.2    Trumpp, A.3
  • 16
    • 23144464363 scopus 로고    scopus 로고
    • Transcriptional regulation and transformation by Myc proteins
    • Adhikary S, Eilers M. Transcriptional regulation and transformation by Myc proteins. Nat Rev Mol Cell Biol 2005;6:635-645.
    • (2005) Nat Rev Mol Cell Biol , vol.6 , pp. 635-645
    • Adhikary, S.1    Eilers, M.2
  • 17
    • 14744288294 scopus 로고    scopus 로고
    • The Myc trilogy: Lord of RNA polymerases
    • Oskarsson T, Trumpp A. The Myc trilogy: Lord of RNA polymerases. Nat Cell Biol 2005;7:215-217.
    • (2005) Nat Cell Biol , vol.7 , pp. 215-217
    • Oskarsson, T.1    Trumpp, A.2
  • 18
    • 0035856918 scopus 로고    scopus 로고
    • c-Myc regulates mammalian body size by controlling cell number but not cell size
    • Trumpp A, Refaeli Y, Oskarsson T, Gasser S, Murphy M, Martin GR, et al. c-Myc regulates mammalian body size by controlling cell number but not cell size. Nature 2001;414:768-773.
    • (2001) Nature , vol.414 , pp. 768-773
    • Trumpp, A.1    Refaeli, Y.2    Oskarsson, T.3    Gasser, S.4    Murphy, M.5    Martin, G.R.6
  • 20
    • 4043110461 scopus 로고    scopus 로고
    • Targeted insertion of an IRES Cre into the Hnf4alpha locus: Cre-mediated recombination in the liver, kidney, and gut epithelium
    • Vincent SD, Robertson EJ. Targeted insertion of an IRES Cre into the Hnf4alpha locus: Cre-mediated recombination in the liver, kidney, and gut epithelium. Genesis 2004;39:206-211.
    • (2004) Genesis , vol.39 , pp. 206-211
    • Vincent, S.D.1    Robertson, E.J.2
  • 21
    • 8644219660 scopus 로고    scopus 로고
    • c-Myc controls the balance between hematopoietic stem cell self-renewal and differentiation
    • Wilson A, Murphy MJ, Oskarsson T, Kaloulis K, Bettess MD, Oser GM, et al. c-Myc controls the balance between hematopoietic stem cell self-renewal and differentiation. Genes Dev 2004;18:2747-2763.
    • (2004) Genes Dev , vol.18 , pp. 2747-2763
    • Wilson, A.1    Murphy, M.J.2    Oskarsson, T.3    Kaloulis, K.4    Bettess, M.D.5    Oser, G.M.6
  • 22
    • 23144446164 scopus 로고    scopus 로고
    • Psarros M, Heber S, Sick M, Thoppae G, Harshman K, Sick B. RACE: Remote Analysis Computation for gene Expression data. Nucleic Acids Res 2005;33.W638-W643.
    • Psarros M, Heber S, Sick M, Thoppae G, Harshman K, Sick B. RACE: Remote Analysis Computation for gene Expression data. Nucleic Acids Res 2005;33.W638-W643.
  • 25
    • 0034750803 scopus 로고    scopus 로고
    • Matrix attachment region-dependent function of the immunoglobulin mu enhancer involves histone acetylation at a distance without changes in enhancer occupancy
    • Fernandez LA, Winkler M, Grosschedl R, Matrix attachment region-dependent function of the immunoglobulin mu enhancer involves histone acetylation at a distance without changes in enhancer occupancy. Mol Cell Biol 2001;21:196-208.
    • (2001) Mol Cell Biol , vol.21 , pp. 196-208
    • Fernandez, L.A.1    Winkler, M.2    Grosschedl, R.3
  • 26
    • 0036765785 scopus 로고    scopus 로고
    • Nuclear pregnane x receptor and constitutive androstane receptor regulate overlapping but distinct sets of genes involved in xenobiotic detoxification
    • Maglich JM, Stoltz CM, Goodwin B, Hawkins-Brown D, Moore JT, Kliewer SA. Nuclear pregnane x receptor and constitutive androstane receptor regulate overlapping but distinct sets of genes involved in xenobiotic detoxification. Mol Pharmacol 2002;62:638-646.
    • (2002) Mol Pharmacol , vol.62 , pp. 638-646
    • Maglich, J.M.1    Stoltz, C.M.2    Goodwin, B.3    Hawkins-Brown, D.4    Moore, J.T.5    Kliewer, S.A.6
  • 27
    • 2542440464 scopus 로고    scopus 로고
    • Interactions between hepatic Mrp4 and Sult2a as revealed by the constitutive androstane receptor and Mrp4 knockout mice
    • Assem M, Schuetz EG, Leggas M, Sun D, Yasuda K Reid G, et al. Interactions between hepatic Mrp4 and Sult2a as revealed by the constitutive androstane receptor and Mrp4 knockout mice. J Biol Chem 2004;279: 22250-22257.
    • (2004) J Biol Chem , vol.279 , pp. 22250-22257
    • Assem, M.1    Schuetz, E.G.2    Leggas, M.3    Sun, D.4    Yasuda, K.5    Reid, G.6
  • 28
    • 33744962967 scopus 로고    scopus 로고
    • Functional inhibitory cross-talk between constitutive androstane receptor and hepatic nuclear factor-4 in hepatic lipid/glucose metabolism is mediated by competition for binding to the DR1 motif and to the common coactivators, GRIP-1 and PGC-1alpha
    • Miao J, Fang S, Bae Y, Kemper JK. Functional inhibitory cross-talk between constitutive androstane receptor and hepatic nuclear factor-4 in hepatic lipid/glucose metabolism is mediated by competition for binding to the DR1 motif and to the common coactivators, GRIP-1 and PGC-1alpha. J Biol Chem 2006;281:14537-14546.
    • (2006) J Biol Chem , vol.281 , pp. 14537-14546
    • Miao, J.1    Fang, S.2    Bae, Y.3    Kemper, J.K.4
  • 29
    • 20344396122 scopus 로고    scopus 로고
    • Preventing re-replication of chromosomal DNA
    • Blow JJ, Dutta A. Preventing re-replication of chromosomal DNA. Nat Rev Mol Cell Biol 2005;6:476-486.
    • (2005) Nat Rev Mol Cell Biol , vol.6 , pp. 476-486
    • Blow, J.J.1    Dutta, A.2
  • 30
    • 0037436391 scopus 로고    scopus 로고
    • Interaction and assembly of murine pre-replicative complex proteins in yeast and mouse cells
    • Kneissl M, Putter V, Szalay AA, Grummt F. Interaction and assembly of murine pre-replicative complex proteins in yeast and mouse cells. J Mol Biol 2003;327:111-128.
    • (2003) J Mol Biol , vol.327 , pp. 111-128
    • Kneissl, M.1    Putter, V.2    Szalay, A.A.3    Grummt, F.4
  • 31
    • 0028931265 scopus 로고
    • Principles of CDK regulation
    • Morgan DO. Principles of CDK regulation. Nature 1995;374:131-134.
    • (1995) Nature , vol.374 , pp. 131-134
    • Morgan, D.O.1
  • 32
    • 18344366048 scopus 로고    scopus 로고
    • Getting in and out of mitosis with Polo-like kinase-1
    • van Vugt MA, Medema RH. Getting in and out of mitosis with Polo-like kinase-1. Oncogene 2005;24:2844-2859.
    • (2005) Oncogene , vol.24 , pp. 2844-2859
    • van Vugt, M.A.1    Medema, R.H.2
  • 33
    • 17644394240 scopus 로고    scopus 로고
    • How do so few control so many?
    • Nasmyth K. How do so few control so many? Cell 2005;120:739-746.
    • (2005) Cell , vol.120 , pp. 739-746
    • Nasmyth, K.1
  • 34
    • 18044396994 scopus 로고    scopus 로고
    • Bub1 and the multilayered inhibition of Cdc20-APC/C in mitosis
    • Vanoosthuyse V, Hardwick KG. Bub1 and the multilayered inhibition of Cdc20-APC/C in mitosis. Trends Cell Biol 2005;15:231-233.
    • (2005) Trends Cell Biol , vol.15 , pp. 231-233
    • Vanoosthuyse, V.1    Hardwick, K.G.2
  • 35
    • 0037168526 scopus 로고    scopus 로고
    • The Forkhead Box m1b transcription factor is essential for hepatocyte DNA replication and mitosis during mouse liver regeneration
    • Wang X, Kiyokawa H, Dennewitz MB, Costa RH. The Forkhead Box m1b transcription factor is essential for hepatocyte DNA replication and mitosis during mouse liver regeneration. Proc Natl Acad Sci U S A 2002; 99:16881-16886.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 16881-16886
    • Wang, X.1    Kiyokawa, H.2    Dennewitz, M.B.3    Costa, R.H.4
  • 36
    • 30944463481 scopus 로고    scopus 로고
    • Gadd45beta is induced through a CAR-dependent, TNF-independent pathway in murine liver hyperplasia
    • Columbano A, Ledda-Columbano GM, Pibiri M, Cossu C, Menegazzi M, Moore DD, et al. Gadd45beta is induced through a CAR-dependent, TNF-independent pathway in murine liver hyperplasia. HEPATOLOGY 2005;42:1118-1126.
    • (2005) HEPATOLOGY , vol.42 , pp. 1118-1126
    • Columbano, A.1    Ledda-Columbano, G.M.2    Pibiri, M.3    Cossu, C.4    Menegazzi, M.5    Moore, D.D.6
  • 38
    • 33746617960 scopus 로고    scopus 로고
    • Skin epidermis lacking the c-Myc gene is resistant to Ras-driven tumorigenesis but can reacquire sensitivity upon additional loss of the p21Cip1 gene
    • Oskarsson T, Essers MA, Dubois N, Offner S, Dubey C, Roger C, et al. Skin epidermis lacking the c-Myc gene is resistant to Ras-driven tumorigenesis but can reacquire sensitivity upon additional loss of the p21Cip1 gene. Genes Dev 2006;20:2024-2029.
    • (2006) Genes Dev , vol.20 , pp. 2024-2029
    • Oskarsson, T.1    Essers, M.A.2    Dubois, N.3    Offner, S.4    Dubey, C.5    Roger, C.6
  • 39
    • 11144353897 scopus 로고    scopus 로고
    • Foxm1b transcription factor is essential for development of hepatocellular carcinomas and is negatively regulated by the p19ARF tumor suppressor
    • Kalinichenko VV, Major ML, Wang X, Petrovic V, Kuechle J, Yoder HM, et al. Foxm1b transcription factor is essential for development of hepatocellular carcinomas and is negatively regulated by the p19ARF tumor suppressor. Genes Dev 2004;18:830-850.
    • (2004) Genes Dev , vol.18 , pp. 830-850
    • Kalinichenko, V.V.1    Major, M.L.2    Wang, X.3    Petrovic, V.4    Kuechle, J.5    Yoder, H.M.6
  • 40
    • 33645821043 scopus 로고    scopus 로고
    • Nuclear receptor-dependent bile acid signaling is required for normal liver regeneration
    • Huang W, Ma K, Zhang J, Qatanani M, Cuvillier J, Liu J, et al. Nuclear receptor-dependent bile acid signaling is required for normal liver regeneration. Science 2006;312:233-236.
    • (2006) Science , vol.312 , pp. 233-236
    • Huang, W.1    Ma, K.2    Zhang, J.3    Qatanani, M.4    Cuvillier, J.5    Liu, J.6
  • 41
    • 33749386211 scopus 로고    scopus 로고
    • FOXM1c transactivates the human c-myc promoter directly via the two TATA boxes P1 and P2
    • Wierstra I, Alves J. FOXM1c transactivates the human c-myc promoter directly via the two TATA boxes P1 and P2. FEBS J 2006;273:4645-4667.
    • (2006) FEBS J , vol.273 , pp. 4645-4667
    • Wierstra, I.1    Alves, J.2
  • 42
    • 33751420809 scopus 로고    scopus 로고
    • FOXM1c and Sp1 transactivate the P1 and P2 promoters of human c-myc synergistically
    • Wierstra I, Alves J. FOXM1c and Sp1 transactivate the P1 and P2 promoters of human c-myc synergistically. Biochem Biophys Res Commun 2007; 352:61-68.
    • (2007) Biochem Biophys Res Commun , vol.352 , pp. 61-68
    • Wierstra, I.1    Alves, J.2
  • 43
    • 0034326247 scopus 로고    scopus 로고
    • Identification of c-myc responsive genes using rat cDNA microarray
    • Guo QM, Malek RL, Kim S, Chiao C, He M, Ruffy M, et al. Identification of c-myc responsive genes using rat cDNA microarray. Cancer Res 2000; 60:5922-5928.
    • (2000) Cancer Res , vol.60 , pp. 5922-5928
    • Guo, Q.M.1    Malek, R.L.2    Kim, S.3    Chiao, C.4    He, M.5    Ruffy, M.6
  • 45
    • 34548074905 scopus 로고    scopus 로고
    • Transplanted hepatocytes over-expressing FoxM1B efficiently repopulate chronically injured mouse liver independent of donor age
    • Brezillon N, Lambert-Blot M, Morosan S, Couton D, Mitchell C, Kremsdorf D, et al. Transplanted hepatocytes over-expressing FoxM1B efficiently repopulate chronically injured mouse liver independent of donor age. Mol Ther 2007;15:1710-1715.
    • (2007) Mol Ther , vol.15 , pp. 1710-1715
    • Brezillon, N.1    Lambert-Blot, M.2    Morosan, S.3    Couton, D.4    Mitchell, C.5    Kremsdorf, D.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.