Receptor tyrosine kinases activate canonical WNT/β-catenin signaling via MAP kinase/LRP6 pathway and direct β-catenin phosphorylation

PLoS ONE

Volumn 7, Issue 4, 2012, Pages

  Krejci, Pavel ^a,b,c   Aklian, Anie ^a   Kaucka, Marketa ^b   Sevcikova, Eva ^b   Prochazkova, Jirina ^b   Masek, Jan Kukla ^b   Mikolka, Pavol ^b   Pospisilova, Tereza ^b   Spoustova, Tereza ^b   Weis, MaryAnn ^d   Paznekas, William A ^e   Wolf, Joshua H ^f   Gutkind, J Silvio ^f   Wilcox, William R ^a,g   Kozubik, Alois ^b,c   Jabs, Ethylin Wang ^e   Bryja, Vitezslav ^b,c   Salazar, Lisa ^h   Vesela, Iva ^b   Balek, Lukas ^b  

^a CEDARS SINAI MEDICAL CENTER   (United States)

^b MASARYK UNIVERSITY   (Czech Republic)

^c INSTITUTE OF BIOPHYSICS   (Czech Republic)

^d UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^e MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^f NATIONAL INSTITUTES OF HEALTH   (United States)

^g UNIVERSITY OF CALIFORNIA   (United States)

^h UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; CADHERIN; EPIDERMAL GROWTH FACTOR RECEPTOR; FIBROBLAST GROWTH FACTOR RECEPTOR 2; FIBROBLAST GROWTH FACTOR RECEPTOR 3; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN 6; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE KINASE A; SERINE; THREONINE; TYROSINE; WNT PROTEIN; GLYCOGEN SYNTHASE KINASE 3; LRP6 PROTEIN, HUMAN;

ANIMAL CELL; ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME MECHANISM; ENZYME PHOSPHORYLATION; MOLECULAR DYNAMICS; NONHUMAN; PHENOTYPIC VARIATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN SECRETION; RAT; TRANS GOLGI NETWORK; UPREGULATION; WNT SIGNALING PATHWAY; CELL STRAIN HEK293; GENE EXPRESSION REGULATION; GENETICS; HUMAN; METABOLISM; PHOSPHORYLATION; SIGNAL TRANSDUCTION;

BETA CATENIN; GENE EXPRESSION REGULATION; GLYCOGEN SYNTHASE KINASE 3; HEK293 CELLS; HUMANS; LOW DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN-6; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTOR PROTEIN-TYROSINE KINASES; WNT PROTEINS; WNT SIGNALING PATHWAY;

EID: 84860449381     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0035826     Document Type: Article

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