Raf/MEK/MAPK signaling stimulates the nuclear translocation and transactivating activity of FOXM1

Methods in Molecular Biology

Volumn 647, Issue , 2010, Pages 113-123

  Ma, Richard Y M ^a   Tong, Tommy H K ^a   Leung, Wai Ying ^a   Yao, Kwok Ming ^a  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Cyclin B1 promoter; FOXM1; G2 M; hTERT BJ1; Nuclear translocation; Raf MEK MAPK signaling; U0126

Indexed keywords

EID: 84934439368     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-60761-738-9_6     Document Type: Article

References (12)

1. Yao K-M, Sha M, Lu Z, Wong GG (1997) Molecular analysis of a novel winged helix protein, WIN: Expression pattern, DNA binding property and alternative splicing within the DNA binding domain. J Biol Chem 272:19827-19836 (Pubitemid 27340077)
2. Ye H, Kelly TF, Samadani U, Lim L, Rubio S, Overdier DG, Roebuck KA, Costa RH (1997) Hepatocyte nuclear factor 3/fork head homolog 11 is expressed in proliferating epithelial and mesenchymal cells of embryonic and adult tissues. Mol Cell Biol 17:1626-1641 (Pubitemid 27097392)
3. Korver W, Roose J, Clevers H (1997) The winged-helix transcription factor Trident is expressed in cycling cells. Nucleic Acids Res 25:1715-1719 (Pubitemid 27303351)
4. Kaestner KH, Knochel W, Martinez DE (2000) Unified nomenclature for the winged helix/forkhead transcription factors. Genes Dev 14:142-146 (Pubitemid 30070978)
5. Leung TWC, Lin SSW, Tsang ACC, Tong CSW, Ching JCY, Leung WY, Gimlich R, Wong GG, Yao K-M (2001) Over-expression of FoxM1 stimulates cyclin B1 expression. FEBS Lett 507:59-66 (Pubitemid 33000299)
6. Laoukili J, Kooistra MRH, Bras A, Kauw J, Kerkhoven RM, Morrison A, Clevers H, Medema RH (2005) FoxM1 is required for execution of the mitotic programme and chromosome stability. Nature Cell Biol 7:126-136 (Pubitemid 40268127)
7. Wang I-C, Chen Y-J, Hughes D, Petrovic V, Major ML, Park HJ, Tan Y, Ackerson T, Costa RH (2005) Forkhead box M1 regulates the transcriptional network of genes essential for mitotic progression and genes encoding the SCF (Skp2-Cks1) ubiquitin ligase. Mol Cell Biol 25:10875-10894 (Pubitemid 41747132)
8. Wonsey DR, Follettie MT (2005) Loss of the forkhead transcription factor FoxM1 causes centrosome amplification and mitotic catastrophe. Cancer Res 65:5181-5189 (Pubitemid 40827327)
9. Ye H, Holterman AX, Yoo KW, Franks RR, Costa RH (1999) Premature expression of the winged helix transcription factor HFH-11B in regenerating mouse liver accelerates hepatocyte entry into S phase. Mol Cell Biol 19:8570-8580 (Pubitemid 30414050)
10. Chen MS, Hurov J, White LS, Woodford-Thomas T, Piwnica-Worms H (2001) Absence of apparent phenotype in mice lacking Cdc25C protein phosphatase. Mol Cell Biol 21:3853-3861 (Pubitemid 32476448)
11. Ma RYM, Tong THK, Cheung AMS, Tsang ACC, Leung WY, Yao K-M (2005) Raf/MEK/MAPK signaling stimulates the nuclear translocation and transactivating activity of FOXM1c. J Cell Sci 118:795-806 (Pubitemid 40372587)
12. Fukuda M, Gotoh I, Adachi M, Gotoh Y, Nishida E (1997) A novel regulatory mechanism in the mitogen-activated protein (MAP) kinase cascade. Role of nuclear export signal of MAP kinase kinase. J Biol Chem 272:32642-32648 (Pubitemid 28011955)