Axin inhibits extracellular signal-regulated kinase pathway by ras degradation via β-catenin

Journal of Biological Chemistry

Volumn 282, Issue 19, 2007, Pages 14482-14492

  Soung, Hoo Jeon ^a   Yoon, Ju Yong ^a   Park, Young Nyun ^b   Jeong, Woo Jeong ^a   Kim, Sewoon ^c   Jho, Eek Hoon ^c   Surh, Young Joon ^d   Choi, Kang Yell ^a  

^a Yonsei University   (South Korea)

^b Yonsei University College of Medicine   (South Korea)

^c University of Seoul   (South Korea)

^d Seoul National University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME INHIBITION; FIBROBLASTS; GROWTH KINETICS; PROTEINS;

AXIN; CARCINOGENESIS; EXTRACELLULAR SIGNAL-REGULATED KINASE (ERK);

HORMONES;

AXIN; BETA CATENIN; EPIDERMAL GROWTH FACTOR; LEUPEPTIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE; MUTANT PROTEIN; PROTEIN INHIBITOR; RAF PROTEIN; RAS PROTEIN; AXIN PROTEIN; EGFR PROTEIN, RAT; EPIDERMAL GROWTH FACTOR RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE; PROTEIN P21; REPRESSOR PROTEIN; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; WNT PROTEIN;

ANIMAL CELL; ARTICLE; CELL GROWTH; CELL PROLIFERATION; CELL STRUCTURE; CELL TRANSFORMATION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME REGULATION; FIBROBLAST; GENE MUTATION; HUMAN; HUMAN CELL; LIVER CELL; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN INDUCTION; RAT; ANIMAL; CELL ADHESION; CELL CYCLE; CELL STRAIN 3T3; CLONOGENIC ASSAY; CYTOLOGY; DRUG ANTAGONISM; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; SIGNAL TRANSDUCTION;

ANIMALS; BETA CATENIN; CELL ADHESION; CELL CYCLE; CELL PROLIFERATION; COLONY-FORMING UNITS ASSAY; EPIDERMAL GROWTH FACTOR; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FIBROBLASTS; GENE EXPRESSION REGULATION; HEPATOCYTES; MAP KINASE KINASE KINASES; MICE; MITOGEN-ACTIVATED PROTEIN KINASES; NIH 3T3 CELLS; ONCOGENE PROTEIN P21(RAS); PROTO-ONCOGENE PROTEINS C-RAF; RATS; RECEPTOR, EPIDERMAL GROWTH FACTOR; REPRESSOR PROTEINS; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; WNT PROTEINS;

EID: 34347231979     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M611129200     Document Type: Article

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