β-catenin signaling involves HGF-enhanced HepG2 scattering through activating MMP-7 transcription

Histochemistry and Cell Biology

Volumn 134, Issue 3, 2010, Pages 285-295

  Pan, Fei Yan ^a   Zhang, Sheng Zhou ^a,d   Xu, Na ^a   Meng, Fan Li ^a   Zhang, Hong Xia ^a   Xue, Bin ^c   Han, Xiao ^d   Li, Chao Jun ^b  

^a NANJING NORMAL UNIVERSITY   (China)

^b MEDICAL SCHOOL OF NANJING UNIVERSITY   (China)

^c ANHUI NORMAL UNIVERSITY   (China)

^d NANJING MEDICAL UNIVERSITY   (China)

Author keywords

catenin; Cell scattering; E cadherin; Hepatocyte growth factor; MMP 7

Indexed keywords

BETA CATENIN; C MET; MATRILYSIN; PROTEIN; SCATTER FACTOR; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR 4; UNCLASSIFIED DRUG; UVOMORULIN; WNT PROTEIN;

ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; LIVER CELL CARCINOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; TRANSCRIPTION INITIATION; TUMOR GROWTH;

BETA CATENIN; CADHERINS; DOWN-REGULATION; ENZYME ACTIVATION; HEP G2 CELLS; HEPATOCYTE GROWTH FACTOR; HUMANS; MATRIX METALLOPROTEINASE 7; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; PROTO-ONCOGENE PROTEINS C-MET; SIGNAL TRANSDUCTION; WNT PROTEINS;

EID: 77956938047     PISSN: 09486143     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00418-010-0729-3     Document Type: Article

References (43)

1. U Apte G Zeng P Muller X Tan A Micsenyi B Cieply C Dai Y Liu KH Kaestner SP Monga 2006 Activation of Wnt/beta-catenin pathway during hepatocyte growth factor-induced hepatomegaly in mice Hepatology 44 992 1002 10.1002/hep.21317 17006939 (Pubitemid 46499261)
2. E Batlle E Sancho C Franc D Domínguez M Monfar J Baulida AG de Herreros 2000 The transcription factor Snail is a repressor of E-cadherin gene expression in epithelial tumour cells Nat Cell Biol 2 84 89 10.1038/35000034 10655587
3. M Bienz 2005 β-catenin: a pivot between cell adhesion and Wnt signalling Curr Biol 15 R64 R67 10.1016/j.cub.2004.12.058 15668160
4. C Birchmeier W Birchmeier E Gherardi GF Vande Woude 2003 Met, metastasis, motility and more Nat Rev Mol Cell Biol 4 915 925 10.1038/nrm1261 14685170 (Pubitemid 37493640)
5. FH Brembeck M Rosário W Birchmeier 2006 Balancing cell adhesion and Wnt signaling, the key role of β-catenin Curr Opin Genet Dev 16 51 59 10.1016/j.gde.2005.12.007 16377174 (Pubitemid 43089612)
6. DM Bryant JL Stow 2004 The ins and outs of E-cadherin trafficking Trends Cell Biol 14 427 434 10.1016/j.tcb.2004.07.007 15308209 (Pubitemid 39092700)
7. Q Cao J Yu SM Dhanasekaran JH Kim RS Mani SA Tomlins R Mehra B Laxman X Cao J Yu CG Kleer S Varambally AM Chinnaiyan 2008 Repression of E-cadherin by the polycomb group protein EZH2 in cancer Oncogene 27 7274 7284 10.1038/onc.2008.333 18806826
8. HC Crawford BM Fingleton LA Rudolph-Owen KJH Goss B Rubinfeld P Polakis LM Matrisian 1999 The metalloproteinase matrilysin is a target of b-catenin transactivation in intestinal tumors Oncogene 18 2883 2891 10.1038/sj.onc. 1202627 10362259 (Pubitemid 29250878)
9. RL Daugherty CJ Gottardi 2007 Phospho-regulation of β-catenin adhesion and signaling functions Physiology 22 303 309 10.1152/physiol.00020. 2007 17928543
10. G Davies WG Jiang MD Mason 2001 Matrilysin mediates extracellular cleavage of E-cadherin from prostate cancer cells a key mechanism in hepatocyte growth factor/scatter factor-induced cell-cell dissociation and in vitro invasion Clin Cancer Res 7 3289 3297 11595727
11. IJ Fidler 2003 The pathogenesis of cancer metastasis: the 'seed and soil' hypothesis revisited Nat Rev Cancer 3 453 458 10.1038/nrc1098 12778135 (Pubitemid 37328849)
12. Y Fujita G Krause M Scheffner D Zechner HEM Leddy J Behrens T Sommer W Birchmeier 2002 Hakai, a c-Cbl-like protein, ubiquitinates and induces endocytosis of the E-cadherin complex Nat Cell Biol 4 222 231 10.1038/ncb758 11836526 (Pubitemid 34218196)
13. Z Gao MS Tretiakova W Liu C Gong PD Farris J Hart 2006 Association of E-cadherin, matrix metalloproteinases, and tissue inhibitors of metalloproteinases with the progression and metastasis of hepatocellular carcinoma Mod Pathol 19 533 540 10.1038/modpathol.3800554 16474379
14. S Grotegut D von Schweinitz G Christofori F Lehembre 2006 Hepatocyte growth factor induces cell scattering through MAPK/Egr-1-mediated upregulation of Snail EMBO J 25 3534 3545 10.1038/sj.emboj.7601213 16858414 (Pubitemid 44264864)
15. BM Gumbiner 2000 Regulation of cadherin adhesive activity J Cell Biol 148 399 404 10.1083/jcb.148.3.399 10662767
16. SU Han HY Lee JH Lee WH Kim H Nam H Kim YK Cho MW Kim KU Lee 2005 Modulation of E-Cadherin by hepatocyte growth factor induces aggressiveness of gastric carcinoma Ann Surg 242 676 683 10.1097/01.sla.0000186171.85804.fe 16244541 (Pubitemid 41567123)
17. TC He S Zhou LT da Costa 1998 A simplified system for generating recombinant adenoviruses Proc Natl Acad Sci USA 95 2509 2514 10.1073/pnas.95.5.2509 9482916 (Pubitemid 28145972)
18. MH Herynk R Tsan R Radinsky GE Gallick 2003 Activation of c-Met in colorectal carcinoma cells leads to constitutive association of tyrosine-phosphorylated β-catenin Clin Exp Metastas 20 291 300 10.1023/A:1024024218529 (Pubitemid 36745657)
19. Y Ichikawa T Ishikawa N Momiyama M Kamiyama H Sakurada R Matsuyama S Hasegawa T Chishima Y Hamaguchi S Fujii 2006 Matrilysin (MMP-7) degrades VE-cadherin and accelerates accumulation of beta-catenin in the nucleus of human umbilical vein endothelial cells Oncol Rep 15 311 315 16391847
20. M Ii H Yamamoto Y Adachi Y Maruyama Y Shinomura 2006 Role of matrix metalloproteinase-7 (matrilysin) in human cancer invasion, apoptosis, growth, and angiogenesis Exp Biol Med 231 20 27
21. WG Jiang TA Martin C Parr G Davies K Matsumoto T Nakamura 2005 Hepatocyte growth factor, its receptor, and their potential value in cancer therapies Crit Rev Oncol Hematol 53 35 69 10.1016/j.critrevonc.2004.09.004 15607934 (Pubitemid 39656109)
22. TN Kunio Matsumoto 2006 Hepatocyte growth factor and the Met system as a mediator of tumor-stromal interactions Int J Cancer 119 477 483 10.1002/ijc.21808 16453287 (Pubitemid 43955698)
23. KH Lee EY Choi MS Hyun BI Jang TN Kim SW Kim SK Song JH Kim JR Kim 2007 Association of extracellular cleavage of E-cadherin mediated by MMP-7 with HGF-induced in vitro invasion in human stomach cancer cells Eur Surg Res 39 208 215 10.1159/000101452 17396032 (Pubitemid 47000367)
24. P Leroy KE Mostov 2007 Slug is required for cell survival during partial epithelial-mesenchymal transition of HGF-induced tubulogenesis Mol Biol Cell 18 1943 1952 10.1091/mbc.E06-09-0823 17344479 (Pubitemid 46717573)
25. E Lesko M Majka 2008 The biological role of HGF-MET axis in tumor growth and development of metastasis Front Biosci 13 1271 1280 10.2741/2760 17981628 (Pubitemid 351594710)
26. JM Llovet A Burroughs J Bruix 2003 Hepatocellular carcinoma Lancet 362 1907 1917 10.1016/S0140-6736(03)14964-1 14667750 (Pubitemid 37518510)
27. ND Marchenko GN Marchenko RN Weinreb JD Lindsey A Kyshtoobayeva HC Crawford AY Strongin 2004 Beta-catenin regulates the gene of MMP-26, a novel metalloproteinase expressed both in carcinomas and normal epithelial cells Int J Biochem Cell Biol 36 942 956 10.1016/j.biocel.2003.12.007 15006646 (Pubitemid 38299409)
28. HG Munshi MS Stack 2006 Reciprocal interactions between adhesion receptor signaling and MMP regulation Cancer Metast Rev 25 45 56 10.1007/s10555-006- 7888-7 (Pubitemid 43723981)
29. T Osada M Sakamoto Y Ino A Iwamatsu Y Matsuno T Muto S Hirohashi 1996 E-cadherin is involved in the intrahepatic metastasis of hepatocellular carcinoma Hepatology 24 1460 1467 10.1002/hep.510240627 8938181
30. C Ponzetto A Bardelli Z Zhen F Maina P dalla Zonca S Giordano A Graziani G Panayotou PM Comoglio 1994 A multifunctional docking site mediates signaling and transformation by the hepatocyte growth factor/scatter factor receptor family Cell 77 261 271 10.1016/0092-8674(94)90318-2 7513258 (Pubitemid 24138623)
31. A Rasola M Fassetta F De Bacco L D'Alessandro D Gramaglia MF Di Renzo PM Comoglio 2007 A positive feedback loop between hepatocyte growth factor receptor and bold beta-catenin sustains colorectal cancer cell invasive growth Oncogene 26 1078 1087 10.1038/sj.onc.1209859 16953230
32. S-M Sheen-Chen Y-W Liu H-L Eng F-F Chou 2005 Serum levels of hepatocyte growth factor in patients with breast cancer Cancer Epiderm Biomar 14 715 717 10.1158/1055-9965.EPI-04-0340 (Pubitemid 40489220)
33. Y Shen DS Hirsch CA Sasiela WJ Wu 2008 Cdc42 regulates E-cadherin ubiquitination and degradation through an epidermal growth factor receptor to Src-mediatedpathway J Biol Chem 283 5127 5137 10.1074/jbc.M703300200 18057010
34. G Shiota J Okano H Kawasaki T Kawamoto T Nakamura 1995 Serum hepatocyte growth factor levels in liver diseases: clinical implications Hepatology 21 106 112 10.1002/hep.1840210119 7806142
35. R Sullivan CH Graham 2007 Hypoxia-driven selection of the metastatic phenotype Cancer Metast Rev 26 319 331 10.1007/s10555-007-9062-2 (Pubitemid 47101665)
36. J Symowicz BP Adley KJ Gleason JJ Johnson S Ghosh DA Fishman LG Hudson MS Stack 2007 Engagement of collagen-binding integrins promotes matrix metalloproteinase-9-dependent E-Cadherin ectodomain shedding in ovarian carcinoma cells Cancer Res 67 2030 2039 10.1158/0008-5472.CAN-06-2808 17332331 (Pubitemid 46424220)
37. EW Thompson DF Newgreen D Tarin 2005 Carcinoma invasion and metastasis: a role for epithelial-mesenchymal transition? Cancer Res 65 5991 5995 10.1158/0008-5472.CAN-05-0616 16024595
38. L Trusolino PM Comoglio 2002 Scatter-factor and semaphorin receptors: cell signaling for invasive growth Nat Rev Cancer 2 289 300 10.1038/nrc779 12001990
39. AP Venook 1994 Treatment of hepatocellular carcinoma: too many options? J Clin Oncol 12 1323 1334 8201395
40. D von Schweinitz A Faundez B Teichmann T Birnbaum A Koch H Hecker S Glueer J Fuchs T Pietsch 2000 Hepatocyte growth-factor-scatter factor can stimulate post-operative tumor-cell proliferation in childhood hepatoblastoma Int J Cancer 85 151 159
41. B Wu SP Crampton CCW Hughes 2007 Wnt signaling induces matrix metalloproteinase expression and regulates T cell transmigration Immunity 26 227 239 10.1016/j.immuni.2006.12.007 17306568 (Pubitemid 46329437)
42. J Zavadil J Haley R Kalluri SK Muthuswamy E Thompson 2008 Epithelial-mesenchymal transition Cancer Res 68 9574 9577 10.1158/0008-5472.CAN- 08-2316 19047131
43. SZ Zhang FY Pan JF Xu J Yuan SY Guo G Dai B Xue WG Shen CJ Wen DH Zhao 2005 Knockdown of c-Met by adenovirus-delivered small interfering RNA inhibits hepatocellular carcinoma growth in vitro and in vivo Mol Cancer Ther 4 1577 1584 10.1158/1535-7163.MCT-05-0106 16227408 (Pubitemid 41556441)