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Volumn 109, Issue , 2012, Pages 463-484

Limiting spinal cord injury by pharmacological intervention

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EID: 84867807348     PISSN: 00729752     EISSN: None     Source Type: Book Series    
DOI: 10.1016/B978-0-444-52137-8.00029-2     Document Type: Chapter
Times cited : (21)

References (256)
  • 1
    • 0030025964 scopus 로고    scopus 로고
    • Mechanisms of secondary injury to spinal cord axons in vitro: role of Na+,Na+-K+-ATPase, the N+-H+ exchanger, and the Na+-Ca2+ exchanger
    • Agrawal S.K., Fehlings M.G. Mechanisms of secondary injury to spinal cord axons in vitro: role of Na+,Na+-K+-ATPase, the N+-H+ exchanger, and the Na+-Ca2+ exchanger. J Neurosci 1996, 16:545-552.
    • (1996) J Neurosci , vol.16 , pp. 545-552
    • Agrawal, S.K.1    Fehlings, M.G.2
  • 2
    • 4544335403 scopus 로고    scopus 로고
    • Spatial and temporal gene expression profiling of the contused rat spinal cord
    • Aimone J.B., Leasure J.L., Perreau V.M., et al. Spatial and temporal gene expression profiling of the contused rat spinal cord. Exp Neurol 2004, 189:204-221.
    • (2004) Exp Neurol , vol.189 , pp. 204-221
    • Aimone, J.B.1    Leasure, J.L.2    Perreau, V.M.3
  • 3
    • 33745145870 scopus 로고    scopus 로고
    • Players in the PARP-1 cell-death pathway: JNK1 joins the cast
    • Alano C.C., Swanson R.A. Players in the PARP-1 cell-death pathway: JNK1 joins the cast. Trends Biochem Sci 2006, 31:309-311.
    • (2006) Trends Biochem Sci , vol.31 , pp. 309-311
    • Alano, C.C.1    Swanson, R.A.2
  • 4
    • 33745457705 scopus 로고    scopus 로고
    • Minocycline inhibits poly(ADP-ribose) polymerase-1 at nanomolar concentrations
    • Alano C.C., Kauppinen T.M., Valls A.V., et al. Minocycline inhibits poly(ADP-ribose) polymerase-1 at nanomolar concentrations. Proc Natl Acad Sci U S A 2006, 103:9685-9690.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 9685-9690
    • Alano, C.C.1    Kauppinen, T.M.2    Valls, A.V.3
  • 5
    • 0023737151 scopus 로고
    • Effects of treatment with U-74006F on neurological outcome following experimental spinal cord injury
    • Anderson D.K., Braughler J.M., Hall E.D., et al. Effects of treatment with U-74006F on neurological outcome following experimental spinal cord injury. J Neurosurg 1988, 69:562-567.
    • (1988) J Neurosurg , vol.69 , pp. 562-567
    • Anderson, D.K.1    Braughler, J.M.2    Hall, E.D.3
  • 6
    • 0025935802 scopus 로고
    • Effect of delayed administration of U74006F (tirilazad mesylate) on recovery of locomotor function after experimental spinal cord injury
    • Anderson D.K., Hall E.D., Braughler J.M., et al. Effect of delayed administration of U74006F (tirilazad mesylate) on recovery of locomotor function after experimental spinal cord injury. J Neurotrauma 1991, 8:187-192.
    • (1991) J Neurotrauma , vol.8 , pp. 187-192
    • Anderson, D.K.1    Hall, E.D.2    Braughler, J.M.3
  • 7
    • 57649233085 scopus 로고    scopus 로고
    • Mitochondrial and nuclear cross talk in cell death: parthanatos
    • Andrabi S.A., Dawson T.M., Dawson V.L. Mitochondrial and nuclear cross talk in cell death: parthanatos. Ann N Y Acad Sci 2008, 1147:233-241.
    • (2008) Ann N Y Acad Sci , vol.1147 , pp. 233-241
    • Andrabi, S.A.1    Dawson, T.M.2    Dawson, V.L.3
  • 8
    • 0034698248 scopus 로고    scopus 로고
    • Riluzole increases high-affinity glutamate uptake in rat spinal cord synaptosomes
    • Azbill R.D., Mu X., Springer J.E. Riluzole increases high-affinity glutamate uptake in rat spinal cord synaptosomes. Brain Res 2000, 871:175-180.
    • (2000) Brain Res , vol.871 , pp. 175-180
    • Azbill, R.D.1    Mu, X.2    Springer, J.E.3
  • 9
    • 0026659498 scopus 로고
    • N-methyl-d-aspartate (NMDA) and opioid receptors mediate dynorphin-induced spinal cord injury: behavioral and histological studies
    • Bakshi R., Ni R.X., Faden A.I. N-methyl-d-aspartate (NMDA) and opioid receptors mediate dynorphin-induced spinal cord injury: behavioral and histological studies. Brain Res 1992, 580:255-264.
    • (1992) Brain Res , vol.580 , pp. 255-264
    • Bakshi, R.1    Ni, R.X.2    Faden, A.I.3
  • 10
    • 0031849873 scopus 로고    scopus 로고
    • Role of calpain in spinal cord injury: effects of calpain and free radical inhibitors
    • Banik N.L., Shields D.C., Ray S., et al. Role of calpain in spinal cord injury: effects of calpain and free radical inhibitors. Ann N Y Acad Sci 1998, 844:131-137.
    • (1998) Ann N Y Acad Sci , vol.844 , pp. 131-137
    • Banik, N.L.1    Shields, D.C.2    Ray, S.3
  • 11
    • 24144485411 scopus 로고    scopus 로고
    • Anti-CD11d antibody treatment reduces free radical formation and cell death in the injured spinal cord of rats
    • Bao F., Dekaban G.A., Weaver L.C. Anti-CD11d antibody treatment reduces free radical formation and cell death in the injured spinal cord of rats. J Neurochem 2005, 94:1361-1373.
    • (2005) J Neurochem , vol.94 , pp. 1361-1373
    • Bao, F.1    Dekaban, G.A.2    Weaver, L.C.3
  • 12
    • 56749098090 scopus 로고    scopus 로고
    • An integrin inhibiting molecule decreases oxidative damage and improves neurological function after spinal cord injury
    • Bao F., Chen Y., Schneider K.A., et al. An integrin inhibiting molecule decreases oxidative damage and improves neurological function after spinal cord injury. Exp Neurol 2008, 214:160-167.
    • (2008) Exp Neurol , vol.214 , pp. 160-167
    • Bao, F.1    Chen, Y.2    Schneider, K.A.3
  • 13
    • 0027162860 scopus 로고
    • Lipid peroxidation in experimental spinal cord injury: time-level relationship
    • Barut S., Canbolat A., Bilge T., et al. Lipid peroxidation in experimental spinal cord injury: time-level relationship. Neurosurg Rev 1993, 16:53-59.
    • (1993) Neurosurg Rev , vol.16 , pp. 53-59
    • Barut, S.1    Canbolat, A.2    Bilge, T.3
  • 14
    • 0032816454 scopus 로고    scopus 로고
    • The effects of FK506 on dorsal column axons following spinal cord injury in adult rats: neuroprotection and local regeneration
    • Bavetta S., Hamlyn P.J., Burnstock G., et al. The effects of FK506 on dorsal column axons following spinal cord injury in adult rats: neuroprotection and local regeneration. Exp Neurol 1999, 158:382-393.
    • (1999) Exp Neurol , vol.158 , pp. 382-393
    • Bavetta, S.1    Hamlyn, P.J.2    Burnstock, G.3
  • 15
    • 0031431557 scopus 로고    scopus 로고
    • Endogenous repair after spinal cord contusion injuries in the rat
    • Beattie M.S., Bresnahan J.C., Komon J., et al. Endogenous repair after spinal cord contusion injuries in the rat. Exp Neurol 1997, 148:453-463.
    • (1997) Exp Neurol , vol.148 , pp. 453-463
    • Beattie, M.S.1    Bresnahan, J.C.2    Komon, J.3
  • 16
    • 0036183630 scopus 로고    scopus 로고
    • The mechanisms of action of PPARs
    • Berger J., Moller D.E. The mechanisms of action of PPARs. Annu Rev Med 2002, 53:409-435.
    • (2002) Annu Rev Med , vol.53 , pp. 409-435
    • Berger, J.1    Moller, D.E.2
  • 17
    • 0020572269 scopus 로고
    • Cellular morphology of chronic spinal cord injury in the cat: analysis of myelinated axons by line-sampling
    • Blight A.R. Cellular morphology of chronic spinal cord injury in the cat: analysis of myelinated axons by line-sampling. Neurosci 1983, 10:521-543.
    • (1983) Neurosci , vol.10 , pp. 521-543
    • Blight, A.R.1
  • 18
    • 0022252884 scopus 로고
    • Delayed demyelination and macrophage invasion: a candidate for secondary cell damage in spinal cord injury
    • Blight A.R. Delayed demyelination and macrophage invasion: a candidate for secondary cell damage in spinal cord injury. Cent Nerv Syst Trauma 1985, 2:299-315.
    • (1985) Cent Nerv Syst Trauma , vol.2 , pp. 299-315
    • Blight, A.R.1
  • 19
    • 0024038942 scopus 로고
    • Mechanical factors in experimental spinal cord injury
    • Blight A. Mechanical factors in experimental spinal cord injury. J Am Paraplegia Soc 1988, 11:26-34.
    • (1988) J Am Paraplegia Soc , vol.11 , pp. 26-34
    • Blight, A.1
  • 20
    • 0022444725 scopus 로고
    • Morphometric analysis of experimental spinal cord injury in the cat: the relation of injury intensity to survival of myelinated axons
    • Blight A.R., DeCrescito V. Morphometric analysis of experimental spinal cord injury in the cat: the relation of injury intensity to survival of myelinated axons. Neurosci 1986, 19:321-341.
    • (1986) Neurosci , vol.19 , pp. 321-341
    • Blight, A.R.1    DeCrescito, V.2
  • 21
    • 0037185379 scopus 로고    scopus 로고
    • Polyunsaturated fatty acids induce ischemic and epileptic tolerance
    • Blondeau N., Widmann C., Lazdunski M., et al. Polyunsaturated fatty acids induce ischemic and epileptic tolerance. Neurosci 2002, 109:231-241.
    • (2002) Neurosci , vol.109 , pp. 231-241
    • Blondeau, N.1    Widmann, C.2    Lazdunski, M.3
  • 22
    • 0027377378 scopus 로고
    • Effects of timing of methylprednisolone or naloxone administration on recovery of segmental and long-tract neurological function in NASCIS 2
    • Bracken M.B., Holford T.R. Effects of timing of methylprednisolone or naloxone administration on recovery of segmental and long-tract neurological function in NASCIS 2. J Neurosurg 1993, 79:500-507.
    • (1993) J Neurosurg , vol.79 , pp. 500-507
    • Bracken, M.B.1    Holford, T.R.2
  • 23
    • 0025344617 scopus 로고
    • A randomized, controlled trial of methylprednisolone or naloxone in the treatment of acute spinal-cord injury. Results of the Second National Acute Spinal Cord Injury Study
    • Bracken M.B., Shepard M.J., Collins W.F., et al. A randomized, controlled trial of methylprednisolone or naloxone in the treatment of acute spinal-cord injury. Results of the Second National Acute Spinal Cord Injury Study. N Engl J Med 1990, 322:1405-1411.
    • (1990) N Engl J Med , vol.322 , pp. 1405-1411
    • Bracken, M.B.1    Shepard, M.J.2    Collins, W.F.3
  • 24
    • 1642422176 scopus 로고    scopus 로고
    • Administration of methylprednisolone for 24 or 48 hours or tirilazad mesylate for 48 hours in the treatment of acute spinal cord injury. Results of the Third National Acute Spinal Cord Injury Randomized Controlled Trial. National Acute Spinal Cord Injury Study
    • Bracken M.B., Shepard M.J., Holford T.R., et al. Administration of methylprednisolone for 24 or 48 hours or tirilazad mesylate for 48 hours in the treatment of acute spinal cord injury. Results of the Third National Acute Spinal Cord Injury Randomized Controlled Trial. National Acute Spinal Cord Injury Study. JAMA 1997, 277:1597-1604.
    • (1997) JAMA , vol.277 , pp. 1597-1604
    • Bracken, M.B.1    Shepard, M.J.2    Holford, T.R.3
  • 25
    • 17144468967 scopus 로고    scopus 로고
    • Methylprednisolone or tirilazad mesylate administration after acute spinal cord injury: 1-year follow up. Results of the Third National Acute Spinal Cord Injury Randomized Controlled Trial
    • Bracken M.B., Shepard M.J., Holford T.R., et al. Methylprednisolone or tirilazad mesylate administration after acute spinal cord injury: 1-year follow up. Results of the Third National Acute Spinal Cord Injury Randomized Controlled Trial. J Neurosurg 1998, 89:699-706.
    • (1998) J Neurosurg , vol.89 , pp. 699-706
    • Bracken, M.B.1    Shepard, M.J.2    Holford, T.R.3
  • 26
    • 34447649920 scopus 로고    scopus 로고
    • Systemic naloxone infusion may trigger spasticity in patients with spinal cord injury: case series
    • Brackett N.L., Ibrahim E., Krassioukov A., et al. Systemic naloxone infusion may trigger spasticity in patients with spinal cord injury: case series. J Spinal Cord Med 2007, 30:272-275.
    • (2007) J Spinal Cord Med , vol.30 , pp. 272-275
    • Brackett, N.L.1    Ibrahim, E.2    Krassioukov, A.3
  • 27
    • 20344394421 scopus 로고    scopus 로고
    • Sex differences and the effect of hormonal therapy on ischemic brain injury
    • Bramlett H.M. Sex differences and the effect of hormonal therapy on ischemic brain injury. Pathophysiology 2005, 12:17-27.
    • (2005) Pathophysiology , vol.12 , pp. 17-27
    • Bramlett, H.M.1
  • 28
    • 20044373442 scopus 로고    scopus 로고
    • Emerging biological roles for erythropoietin in the nervous system
    • Brines M., Cerami A. Emerging biological roles for erythropoietin in the nervous system. Nat Rev Neurosci 2005, 6:484-494.
    • (2005) Nat Rev Neurosci , vol.6 , pp. 484-494
    • Brines, M.1    Cerami, A.2
  • 29
    • 6944237300 scopus 로고    scopus 로고
    • Erythropoietin mediates tissue protection through an erythropoietin and common beta-subunit heteroreceptor
    • Brines M., Grasso G., Fiordaliso F., et al. Erythropoietin mediates tissue protection through an erythropoietin and common beta-subunit heteroreceptor. Proc Natl Acad Sci U S A 2004, 101:14907-14912.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 14907-14912
    • Brines, M.1    Grasso, G.2    Fiordaliso, F.3
  • 30
    • 0032125525 scopus 로고    scopus 로고
    • Spontaneous longitudinally orientated axonal regeneration is associated with the Schwann cell framework within the lesion site following spinal cord compression injury of the rat
    • Brook G.A., Plate D., Franzen R., et al. Spontaneous longitudinally orientated axonal regeneration is associated with the Schwann cell framework within the lesion site following spinal cord compression injury of the rat. J Neurosci Res 1998, 53:51-65.
    • (1998) J Neurosci Res , vol.53 , pp. 51-65
    • Brook, G.A.1    Plate, D.2    Franzen, R.3
  • 31
    • 0037971463 scopus 로고    scopus 로고
    • N-3 polyunsaturated fatty acids and inflammation: from molecular biology to the clinic
    • Calder P.C. N-3 polyunsaturated fatty acids and inflammation: from molecular biology to the clinic. Lipids 2003, 38:343-352.
    • (2003) Lipids , vol.38 , pp. 343-352
    • Calder, P.C.1
  • 32
    • 0032079920 scopus 로고    scopus 로고
    • Acute inflammatory response in spinal cord following impact injury
    • Carlson S.L., Parrish M.E., Springer J.E., et al. Acute inflammatory response in spinal cord following impact injury. Exp Neurol 1998, 151:77-88.
    • (1998) Exp Neurol , vol.151 , pp. 77-88
    • Carlson, S.L.1    Parrish, M.E.2    Springer, J.E.3
  • 33
    • 16844364295 scopus 로고    scopus 로고
    • Effects of epidural hypothermic saline infusion on locomotor outcome and tissue preservation after moderate thoracic spinal cord contusion in rats
    • Casas C.E., Herrera L.P., Prusmack C., et al. Effects of epidural hypothermic saline infusion on locomotor outcome and tissue preservation after moderate thoracic spinal cord contusion in rats. J Neurosurg Spine 2005, 2:308-318.
    • (2005) J Neurosurg Spine , vol.2 , pp. 308-318
    • Casas, C.E.1    Herrera, L.P.2    Prusmack, C.3
  • 34
    • 0036144964 scopus 로고    scopus 로고
    • New vascular tissue rapidly replaces neural parenchyma and vessels destroyed by a contusion injury to the rat spinal cord
    • Casella G.T., Marcillo A., Bunge M.B., et al. New vascular tissue rapidly replaces neural parenchyma and vessels destroyed by a contusion injury to the rat spinal cord. Exp Neurol 2002, 173:63-76.
    • (2002) Exp Neurol , vol.173 , pp. 63-76
    • Casella, G.T.1    Marcillo, A.2    Bunge, M.B.3
  • 35
    • 45849102029 scopus 로고    scopus 로고
    • Neuroprotective actions of melanocortins: a therapeutic opportunity
    • Catania A. Neuroprotective actions of melanocortins: a therapeutic opportunity. Trends Neurosci 2008, 31:353-360.
    • (2008) Trends Neurosci , vol.31 , pp. 353-360
    • Catania, A.1
  • 36
    • 15744387138 scopus 로고    scopus 로고
    • Effect of combined treatment with melatonin and methylprednisolone on neurological recovery after experimental spinal cord injury
    • Cayli S.R., Kocak A., Yilmaz U., et al. Effect of combined treatment with melatonin and methylprednisolone on neurological recovery after experimental spinal cord injury. Eur Spine J 2004, 13:724-732.
    • (2004) Eur Spine J , vol.13 , pp. 724-732
    • Cayli, S.R.1    Kocak, A.2    Yilmaz, U.3
  • 37
    • 0037133191 scopus 로고    scopus 로고
    • Erythropoietin prevents motor neuron apoptosis and neurologic disability in experimental spinal cord ischemic injury
    • Celik M., Gokmen N., Erbayraktar S., et al. Erythropoietin prevents motor neuron apoptosis and neurologic disability in experimental spinal cord ischemic injury. Proc Natl Acad Sci U S A 2002, 99:2258-2263.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 2258-2263
    • Celik, M.1    Gokmen, N.2    Erbayraktar, S.3
  • 38
    • 33745501785 scopus 로고    scopus 로고
    • 17beta-estradiol is protective in spinal cord injury in post- and pre-menopausal rats
    • Chaovipoch P., Jelks K.A., Gerhold L.M., et al. 17beta-estradiol is protective in spinal cord injury in post- and pre-menopausal rats. J Neurotrauma 2006, 23:830-852.
    • (2006) J Neurotrauma , vol.23 , pp. 830-852
    • Chaovipoch, P.1    Jelks, K.A.2    Gerhold, L.M.3
  • 39
    • 34047158711 scopus 로고    scopus 로고
    • Contusion, dislocation, and distraction: primary hemorrhage and membrane permeability in distinct mechanisms of spinal cord injury
    • Choo A.M., Liu J., Lam C.K., et al. Contusion, dislocation, and distraction: primary hemorrhage and membrane permeability in distinct mechanisms of spinal cord injury. J Neurosurg Spine 2007, 6:255-266.
    • (2007) J Neurosurg Spine , vol.6 , pp. 255-266
    • Choo, A.M.1    Liu, J.2    Lam, C.K.3
  • 40
    • 47349105023 scopus 로고    scopus 로고
    • Secondary pathology following contusion, dislocation, and distraction spinal cord injuries
    • Choo A.M., Liu J., Dvorak M., et al. Secondary pathology following contusion, dislocation, and distraction spinal cord injuries. Exp Neurol 2008, 212:490-506.
    • (2008) Exp Neurol , vol.212 , pp. 490-506
    • Choo, A.M.1    Liu, J.2    Dvorak, M.3
  • 41
    • 0018129782 scopus 로고
    • Inhibition of Na+-K+-activated ATPase activity following experimental spinal cord trauma
    • Clendenon N.R., Allen N., Gordon W.A., et al. Inhibition of Na+-K+-activated ATPase activity following experimental spinal cord trauma. J Neurosurg 1978, 49:563-568.
    • (1978) J Neurosurg , vol.49 , pp. 563-568
    • Clendenon, N.R.1    Allen, N.2    Gordon, W.A.3
  • 42
    • 0027954265 scopus 로고
    • The effects of methylprednisolone and the ganglioside GM1 on acute spinal cord injury in rats
    • Constantini S., Young W. The effects of methylprednisolone and the ganglioside GM1 on acute spinal cord injury in rats. J Neurosurg 1994, 80:97-111.
    • (1994) J Neurosurg , vol.80 , pp. 97-111
    • Constantini, S.1    Young, W.2
  • 43
    • 0031015075 scopus 로고    scopus 로고
    • Apoptosis and delayed degeneration after spinal cord injury in rats and monkeys
    • Crowe M.J., Bresnahan J.C., Shuman S.L., et al. Apoptosis and delayed degeneration after spinal cord injury in rats and monkeys. Nat Med 1997, 3:73-76.
    • (1997) Nat Med , vol.3 , pp. 73-76
    • Crowe, M.J.1    Bresnahan, J.C.2    Shuman, S.L.3
  • 44
    • 33747349769 scopus 로고    scopus 로고
    • Debate: " is increasing neuroinflammation beneficial for neural repair?"
    • Crutcher K.A., Gendelman H.E., Kipnis J., et al. Debate: " is increasing neuroinflammation beneficial for neural repair?" J Neuroimmune Pharmacol 2006, 1:195-211.
    • (2006) J Neuroimmune Pharmacol , vol.1 , pp. 195-211
    • Crutcher, K.A.1    Gendelman, H.E.2    Kipnis, J.3
  • 45
    • 39449092068 scopus 로고    scopus 로고
    • Effect of 17beta-estradiol on signal transduction pathways and secondary damage in experimental spinal cord trauma
    • Cuzzocrea S., Genovese T., Mazzon E., et al. Effect of 17beta-estradiol on signal transduction pathways and secondary damage in experimental spinal cord trauma. Shock 2008, 29:362-371.
    • (2008) Shock , vol.29 , pp. 362-371
    • Cuzzocrea, S.1    Genovese, T.2    Mazzon, E.3
  • 46
    • 0031938415 scopus 로고    scopus 로고
    • Comparative effects of the N-methyl-d-aspartate antagonist MK-801 and the calcium channel blocker KB-2796 on neurologic and metabolic recovery after spinal cord ischemia
    • Danielisova V., Chavko M. Comparative effects of the N-methyl-d-aspartate antagonist MK-801 and the calcium channel blocker KB-2796 on neurologic and metabolic recovery after spinal cord ischemia. Exp Neurol 1998, 149:203-208.
    • (1998) Exp Neurol , vol.149 , pp. 203-208
    • Danielisova, V.1    Chavko, M.2
  • 47
    • 25144506952 scopus 로고    scopus 로고
    • Gene expression profiling of experimental traumatic spinal cord injury as a function of distance from impact site and injury severity
    • De Biase A., Knoblach S.M., Di Giovanni S., et al. Gene expression profiling of experimental traumatic spinal cord injury as a function of distance from impact site and injury severity. Physiol Genomics 2005, 22:368-381.
    • (2005) Physiol Genomics , vol.22 , pp. 368-381
    • De Biase, A.1    Knoblach, S.M.2    Di Giovanni, S.3
  • 48
    • 33646867634 scopus 로고    scopus 로고
    • Progesterone treatment of spinal cord injury: effects on receptors, neurotrophins, and myelination
    • De Nicola A.F., Gonzalez S.L., Labombarda F., et al. Progesterone treatment of spinal cord injury: effects on receptors, neurotrophins, and myelination. J Mol Neurosci 2006, 28:3-15.
    • (2006) J Mol Neurosci , vol.28 , pp. 3-15
    • De Nicola, A.F.1    Gonzalez, S.L.2    Labombarda, F.3
  • 49
    • 60949098212 scopus 로고    scopus 로고
    • Atorvastatin prevents early apoptosis after thoracic spinal cord contusion injury and promotes locomotion recovery
    • Dery M.A., Rousseau G., Benderdour M., et al. Atorvastatin prevents early apoptosis after thoracic spinal cord contusion injury and promotes locomotion recovery. Neurosci Lett 2009, 453:73-76.
    • (2009) Neurosci Lett , vol.453 , pp. 73-76
    • Dery, M.A.1    Rousseau, G.2    Benderdour, M.3
  • 50
    • 67650290809 scopus 로고    scopus 로고
    • Therapeutic hypothermia for spinal cord injury
    • Dietrich W.D. Therapeutic hypothermia for spinal cord injury. Crit Care Med 2009, 37:S238-S242.
    • (2009) Crit Care Med , vol.37
    • Dietrich, W.D.1
  • 51
    • 33750696659 scopus 로고    scopus 로고
    • A therapeutic time window for anti-CD 11d monoclonal antibody treatment yielding reduced secondary tissue damage and enhanced behavioral recovery following severe spinal cord injury
    • Ditor D.S., Bao F., Chen Y., et al. A therapeutic time window for anti-CD 11d monoclonal antibody treatment yielding reduced secondary tissue damage and enhanced behavioral recovery following severe spinal cord injury. J Neurosurg Spine 2006, 5:343-352.
    • (2006) J Neurosurg Spine , vol.5 , pp. 343-352
    • Ditor, D.S.1    Bao, F.2    Chen, Y.3
  • 52
    • 0029753270 scopus 로고    scopus 로고
    • The pharmacology and mechanism of action of riluzole
    • Doble A. The pharmacology and mechanism of action of riluzole. Neurology 1996, 47:S233-S241.
    • (1996) Neurology , vol.47
    • Doble, A.1
  • 53
    • 38749086493 scopus 로고    scopus 로고
    • Inflammation and its role in neuroprotection, axonal regeneration and functional recovery after spinal cord injury
    • Donnelly D.J., Popovich P.G. Inflammation and its role in neuroprotection, axonal regeneration and functional recovery after spinal cord injury. Exp Neurol 2008, 209:378-388.
    • (2008) Exp Neurol , vol.209 , pp. 378-388
    • Donnelly, D.J.1    Popovich, P.G.2
  • 54
    • 0036316259 scopus 로고    scopus 로고
    • GM1 ganglioside induces phosphorylation and activation of Trk and Erk in brain
    • Duchemin A.M., Ren Q., Mo L., et al. GM1 ganglioside induces phosphorylation and activation of Trk and Erk in brain. J Neurochem 2002, 81:696-707.
    • (2002) J Neurochem , vol.81 , pp. 696-707
    • Duchemin, A.M.1    Ren, Q.2    Mo, L.3
  • 55
    • 0034806962 scopus 로고    scopus 로고
    • Acute spinal cord injury, part I: pathophysiologic mechanisms
    • Dumont R.J., Okonkwo D.O., Verma S., et al. Acute spinal cord injury, part I: pathophysiologic mechanisms. Clin Neuropharmacol 2001, 24:254-264.
    • (2001) Clin Neuropharmacol , vol.24 , pp. 254-264
    • Dumont, R.J.1    Okonkwo, D.O.2    Verma, S.3
  • 56
    • 0036705708 scopus 로고    scopus 로고
    • Erythropoietin therapy for acute stroke is both safe and beneficial
    • Ehrenreich H., Hasselblatt M., Dembowski C., et al. Erythropoietin therapy for acute stroke is both safe and beneficial. Mol Med 2002, 8:495-505.
    • (2002) Mol Med , vol.8 , pp. 495-505
    • Ehrenreich, H.1    Hasselblatt, M.2    Dembowski, C.3
  • 57
    • 0031783714 scopus 로고    scopus 로고
    • Apoptosis after traumatic human spinal cord injury
    • Emery E., Aldana P., Bunge M.B., et al. Apoptosis after traumatic human spinal cord injury. J Neurosurg 1998, 89:911-920.
    • (1998) J Neurosurg , vol.89 , pp. 911-920
    • Emery, E.1    Aldana, P.2    Bunge, M.B.3
  • 58
    • 0037974734 scopus 로고    scopus 로고
    • Asialoerythropoietin is a nonerythropoietic cytokine with broad neuroprotective activity in vivo
    • Erbayraktar S., Grasso G., Sfacteria A., et al. Asialoerythropoietin is a nonerythropoietic cytokine with broad neuroprotective activity in vivo. Proc Natl Acad Sci U S A 2003, 100:6741-6746.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 6741-6746
    • Erbayraktar, S.1    Grasso, G.2    Sfacteria, A.3
  • 59
    • 49549105511 scopus 로고    scopus 로고
    • Melatonin regulates matrix metalloproteinases after traumatic experimental spinal cord injury
    • Esposito E., Genovese T., Caminiti R., et al. Melatonin regulates matrix metalloproteinases after traumatic experimental spinal cord injury. J Pineal Res 2008, 45:149-156.
    • (2008) J Pineal Res , vol.45 , pp. 149-156
    • Esposito, E.1    Genovese, T.2    Caminiti, R.3
  • 60
    • 57149142404 scopus 로고    scopus 로고
    • Melatonin reduces stress-activated/mitogen-activated protein kinases in spinal cord injury
    • Esposito E., Genovese T., Caminiti R., et al. Melatonin reduces stress-activated/mitogen-activated protein kinases in spinal cord injury. J Pineal Res 2009, 46:79-86.
    • (2009) J Pineal Res , vol.46 , pp. 79-86
    • Esposito, E.1    Genovese, T.2    Caminiti, R.3
  • 61
    • 0019491552 scopus 로고
    • Opiate antagonist improves neurologic recovery after spinal injury
    • Faden A.I., Jacobs T.P., Holaday J.W. Opiate antagonist improves neurologic recovery after spinal injury. Science 1981, 211:493-494.
    • (1981) Science , vol.211 , pp. 493-494
    • Faden, A.I.1    Jacobs, T.P.2    Holaday, J.W.3
  • 62
    • 0021803767 scopus 로고
    • Endogenous opioid immunoreactivity in rat spinal cord following traumatic injury
    • Faden A.I., Molineaux C.J., Rosenberger J.G., et al. Endogenous opioid immunoreactivity in rat spinal cord following traumatic injury. Ann Neurol 1985, 17:386-390.
    • (1985) Ann Neurol , vol.17 , pp. 386-390
    • Faden, A.I.1    Molineaux, C.J.2    Rosenberger, J.G.3
  • 63
    • 0023752736 scopus 로고
    • Effects of BW755C, a mixed cyclo-oxygenase-lipoxygenase inhibitor, following traumatic spinal cord injury in rats
    • Faden A.I., Lemke M., Demediuk P. Effects of BW755C, a mixed cyclo-oxygenase-lipoxygenase inhibitor, following traumatic spinal cord injury in rats. Brain Res 1988, 463:63-68.
    • (1988) Brain Res , vol.463 , pp. 63-68
    • Faden, A.I.1    Lemke, M.2    Demediuk, P.3
  • 64
    • 0023911427 scopus 로고
    • Opiate-receptor antagonist nalmefene improves neurological recovery after traumatic spinal cord injury in rats through a central mechanism
    • Faden A.I., Sacksen I., Noble L.J. Opiate-receptor antagonist nalmefene improves neurological recovery after traumatic spinal cord injury in rats through a central mechanism. J Pharmacol Exp Ther 1988, 245:742-748.
    • (1988) J Pharmacol Exp Ther , vol.245 , pp. 742-748
    • Faden, A.I.1    Sacksen, I.2    Noble, L.J.3
  • 65
    • 36448947190 scopus 로고    scopus 로고
    • Comparison of biochemical effects of statins and fish oil in brain: the battle of the titans
    • Farooqui A.A., Ong W.Y., Horrocks L.A., et al. Comparison of biochemical effects of statins and fish oil in brain: the battle of the titans. Brain Res Brain Res Rev 2007, 56:443-471.
    • (2007) Brain Res Brain Res Rev , vol.56 , pp. 443-471
    • Farooqui, A.A.1    Ong, W.Y.2    Horrocks, L.A.3
  • 66
    • 1542317072 scopus 로고    scopus 로고
    • Reactive astrocytes protect tissue and preserve function after spinal cord injury
    • Faulkner J.R., Herrmann J.E., Woo M.J., et al. Reactive astrocytes protect tissue and preserve function after spinal cord injury. J Neurosci 2004, 24:2143-2155.
    • (2004) J Neurosci , vol.24 , pp. 2143-2155
    • Faulkner, J.R.1    Herrmann, J.E.2    Woo, M.J.3
  • 67
    • 33846906034 scopus 로고    scopus 로고
    • Effects of progesterone on experimental spinal cord injury
    • Fee D.B., Swartz K.R., Joy K.M., et al. Effects of progesterone on experimental spinal cord injury. Brain Res 2007, 1137:146-152.
    • (2007) Brain Res , vol.1137 , pp. 146-152
    • Fee, D.B.1    Swartz, K.R.2    Joy, K.M.3
  • 68
    • 33646598662 scopus 로고    scopus 로고
    • Minocycline neuroprotects, reduces microgliosis, and inhibits caspase protease expression early after spinal cord injury
    • Festoff B.W., Ameenuddin S., Arnold P.M., et al. Minocycline neuroprotects, reduces microgliosis, and inhibits caspase protease expression early after spinal cord injury. J Neurochem 2006, 97:1314-1326.
    • (2006) J Neurochem , vol.97 , pp. 1314-1326
    • Festoff, B.W.1    Ameenuddin, S.2    Arnold, P.M.3
  • 69
    • 0022243894 scopus 로고
    • A phase I trial of naloxone treatment in acute spinal cord injury
    • Flamm E.S., Young W., Collins W.F., et al. A phase I trial of naloxone treatment in acute spinal cord injury. J Neurosurg 1985, 63:390-397.
    • (1985) J Neurosurg , vol.63 , pp. 390-397
    • Flamm, E.S.1    Young, W.2    Collins, W.F.3
  • 70
    • 33845332735 scopus 로고    scopus 로고
    • The cellular inflammatory response in human spinal cords after injury
    • Fleming J.C., Norenberg M.D., Ramsay D.A., et al. The cellular inflammatory response in human spinal cords after injury. Brain 2006, 129:3249-3269.
    • (2006) Brain , vol.129 , pp. 3249-3269
    • Fleming, J.C.1    Norenberg, M.D.2    Ramsay, D.A.3
  • 71
    • 56749170671 scopus 로고    scopus 로고
    • Alpha4beta1 integrin blockade after spinal cord injury decreases damage and improves neurological function
    • Fleming J.C., Bao F., Chen Y., et al. Alpha4beta1 integrin blockade after spinal cord injury decreases damage and improves neurological function. Exp Neurol 2008, 214:147-159.
    • (2008) Exp Neurol , vol.214 , pp. 147-159
    • Fleming, J.C.1    Bao, F.2    Chen, Y.3
  • 72
    • 33847072701 scopus 로고    scopus 로고
    • Recovery from spinal cord injury in tumor necrosis factor-alpha, signal transducers and activators of transcription 4 and signal transducers and activators of transcription 6 null mice
    • Fraidakis M.J., Kiyotani T., Pernold K., et al. Recovery from spinal cord injury in tumor necrosis factor-alpha, signal transducers and activators of transcription 4 and signal transducers and activators of transcription 6 null mice. NeuroReport 2007, 18:185-189.
    • (2007) NeuroReport , vol.18 , pp. 185-189
    • Fraidakis, M.J.1    Kiyotani, T.2    Pernold, K.3
  • 73
    • 0032528154 scopus 로고    scopus 로고
    • Cyclosporin A, but not FK 506, protects mitochondria and neurons against hypoglycemic damage and implicates the mitochondrial permeability transition in cell death
    • Friberg H., Ferrand-Drake M., Bengtsson F., et al. Cyclosporin A, but not FK 506, protects mitochondria and neurons against hypoglycemic damage and implicates the mitochondrial permeability transition in cell death. J Neurosci 1998, 18:5151-5159.
    • (1998) J Neurosci , vol.18 , pp. 5151-5159
    • Friberg, H.1    Ferrand-Drake, M.2    Bengtsson, F.3
  • 74
    • 34247168756 scopus 로고    scopus 로고
    • Nonsteroidal anti-inflammatory drugs promote axon regeneration via RhoA inhibition
    • Fu Q., Hue J., Li S. Nonsteroidal anti-inflammatory drugs promote axon regeneration via RhoA inhibition. J Neurosci 2007, 27:4154-4164.
    • (2007) J Neurosci , vol.27 , pp. 4154-4164
    • Fu, Q.1    Hue, J.2    Li, S.3
  • 75
    • 0034000083 scopus 로고    scopus 로고
    • Potent protective effects of melatonin on experimental spinal cord injury
    • Fujimoto T., Nakamura T., Ikeda T., et al. Potent protective effects of melatonin on experimental spinal cord injury. Spine 2000, 25:769-775.
    • (2000) Spine , vol.25 , pp. 769-775
    • Fujimoto, T.1    Nakamura, T.2    Ikeda, T.3
  • 76
    • 0026432654 scopus 로고
    • Recovery of motor function after spinal cord injury - a randomized, placebo-controlled trial with GM-1 ganglioside
    • Geisler F.H., Dorsey F.C., Coleman W.P. Recovery of motor function after spinal cord injury - a randomized, placebo-controlled trial with GM-1 ganglioside. N Engl J Med 1991, 324:1829-1838.
    • (1991) N Engl J Med , vol.324 , pp. 1829-1838
    • Geisler, F.H.1    Dorsey, F.C.2    Coleman, W.P.3
  • 77
    • 0035893918 scopus 로고    scopus 로고
    • The Sygen multicenter acute spinal cord injury study
    • Geisler F.H., Coleman W.P., Grieco G., et al. The Sygen multicenter acute spinal cord injury study. Spine 2001, 26:S87-S98.
    • (2001) Spine , vol.26
    • Geisler, F.H.1    Coleman, W.P.2    Grieco, G.3
  • 78
    • 15444378210 scopus 로고    scopus 로고
    • Attenuation in the evolution of experimental spinal cord trauma by treatment with melatonin
    • Genovese T., Mazzon E., Muia C., et al. Attenuation in the evolution of experimental spinal cord trauma by treatment with melatonin. J Pineal Res 2005, 38:198-208.
    • (2005) J Pineal Res , vol.38 , pp. 198-208
    • Genovese, T.1    Mazzon, E.2    Muia, C.3
  • 79
    • 13244252358 scopus 로고    scopus 로고
    • Inhibitors of poly(ADP-ribose) polymerase modulate signal transduction pathways and secondary damage in experimental spinal cord trauma
    • Genovese T., Mazzon E., Muia C., et al. Inhibitors of poly(ADP-ribose) polymerase modulate signal transduction pathways and secondary damage in experimental spinal cord trauma. J Pharmacol Exp Ther 2005, 312:449-457.
    • (2005) J Pharmacol Exp Ther , vol.312 , pp. 449-457
    • Genovese, T.1    Mazzon, E.2    Muia, C.3
  • 80
    • 33644768268 scopus 로고    scopus 로고
    • Immunomodulatory effects of etanercept in an experimental model of spinal cord injury
    • Genovese T., Mazzon E., Crisafulli C., et al. Immunomodulatory effects of etanercept in an experimental model of spinal cord injury. J Pharmacol Exp Ther 2006, 316:1006-1016.
    • (2006) J Pharmacol Exp Ther , vol.316 , pp. 1006-1016
    • Genovese, T.1    Mazzon, E.2    Crisafulli, C.3
  • 81
    • 34447527588 scopus 로고    scopus 로고
    • Effects of combination of melatonin and dexamethasone on secondary injury in an experimental mice model of spinal cord trauma
    • Genovese T., Mazzon E., Crisafulli C., et al. Effects of combination of melatonin and dexamethasone on secondary injury in an experimental mice model of spinal cord trauma. J Pineal Res 2007, 43:140-153.
    • (2007) J Pineal Res , vol.43 , pp. 140-153
    • Genovese, T.1    Mazzon, E.2    Crisafulli, C.3
  • 82
    • 37549029154 scopus 로고    scopus 로고
    • TNF-alpha blockage in a mouse model of SCI: evidence for improved outcome
    • Genovese T., Mazzon E., Crisafulli C., et al. TNF-alpha blockage in a mouse model of SCI: evidence for improved outcome. Shock 2008, 29:32-41.
    • (2008) Shock , vol.29 , pp. 32-41
    • Genovese, T.1    Mazzon, E.2    Crisafulli, C.3
  • 83
    • 38849121453 scopus 로고    scopus 로고
    • Effects of zileuton and montelukast in mouse experimental spinal cord injury
    • Genovese T., Rossi A., Mazzon E., et al. Effects of zileuton and montelukast in mouse experimental spinal cord injury. Br J Pharmacol 2008, 153:568-582.
    • (2008) Br J Pharmacol , vol.153 , pp. 568-582
    • Genovese, T.1    Rossi, A.2    Mazzon, E.3
  • 84
    • 35048890497 scopus 로고    scopus 로고
    • Therapeutic neutralization of CXCL10 decreases secondary degeneration and functional deficit after spinal cord injury in mice
    • Gonzalez R., Hickey M.J., Espinosa J.M., et al. Therapeutic neutralization of CXCL10 decreases secondary degeneration and functional deficit after spinal cord injury in mice. Regen Med 2007, 2:771-783.
    • (2007) Regen Med , vol.2 , pp. 771-783
    • Gonzalez, R.1    Hickey, M.J.2    Espinosa, J.M.3
  • 85
    • 0037047154 scopus 로고    scopus 로고
    • Recombinant human erythropoietin counteracts secondary injury and markedly enhances neurological recovery from experimental spinal cord trauma
    • Gorio A., Gokmen N., Erbayraktar S., et al. Recombinant human erythropoietin counteracts secondary injury and markedly enhances neurological recovery from experimental spinal cord trauma. Proc Natl Acad Sci U S A 2002, 99:9450-9455.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 9450-9455
    • Gorio, A.1    Gokmen, N.2    Erbayraktar, S.3
  • 86
    • 2142821430 scopus 로고    scopus 로고
    • Transient blockade of the CD11d/CD18 integrin reduces secondary damage after spinal cord injury, improving sensory, autonomic, and motor function
    • Gris D., Marsh D.R., Oatway M.A., et al. Transient blockade of the CD11d/CD18 integrin reduces secondary damage after spinal cord injury, improving sensory, autonomic, and motor function. J Neurosci 2004, 24:4043-4051.
    • (2004) J Neurosci , vol.24 , pp. 4043-4051
    • Gris, D.1    Marsh, D.R.2    Oatway, M.A.3
  • 87
    • 22044435518 scopus 로고    scopus 로고
    • Comparison of effects of methylprednisolone and anti-CD11d antibody treatments on autonomic dysreflexia after spinal cord injury
    • Gris D., Marsh D.R., Dekaban G.A., et al. Comparison of effects of methylprednisolone and anti-CD11d antibody treatments on autonomic dysreflexia after spinal cord injury. Exp Neurol 2005, 194:541-549.
    • (2005) Exp Neurol , vol.194 , pp. 541-549
    • Gris, D.1    Marsh, D.R.2    Dekaban, G.A.3
  • 88
    • 0034085532 scopus 로고    scopus 로고
    • Changes in NMDA receptor subunit expression in response to contusive spinal cord injury
    • Grossman S.D., Wolfe B.B., Yasuda R.P., et al. Changes in NMDA receptor subunit expression in response to contusive spinal cord injury. J Neurochem 2000, 75:174-184.
    • (2000) J Neurochem , vol.75 , pp. 174-184
    • Grossman, S.D.1    Wolfe, B.B.2    Yasuda, R.P.3
  • 89
    • 0035074297 scopus 로고    scopus 로고
    • Temporal-spatial pattern of acute neuronal and glial loss after spinal cord contusion
    • Grossman S.D., Rosenberg L.J., Wrathall J.R. Temporal-spatial pattern of acute neuronal and glial loss after spinal cord contusion. Exp Neurol 2001, 168:273-282.
    • (2001) Exp Neurol , vol.168 , pp. 273-282
    • Grossman, S.D.1    Rosenberg, L.J.2    Wrathall, J.R.3
  • 90
    • 14844313297 scopus 로고    scopus 로고
    • Demyelination and Schwann cell responses adjacent to injury epicenter cavities following chronic human spinal cord injury
    • Guest J.D., Hiester E.D., Bunge R.P. Demyelination and Schwann cell responses adjacent to injury epicenter cavities following chronic human spinal cord injury. Exp Neurol 2005, 192:384-393.
    • (2005) Exp Neurol , vol.192 , pp. 384-393
    • Guest, J.D.1    Hiester, E.D.2    Bunge, R.P.3
  • 91
    • 59749085965 scopus 로고    scopus 로고
    • Lack of neuroprotection with pharmacological pretreatment in a paradigm for anticipated spinal cord lesions
    • Guizar-Sahagun G., Rodriguez-Balderas C.A., Franco-Bourland R.E., et al. Lack of neuroprotection with pharmacological pretreatment in a paradigm for anticipated spinal cord lesions. Spinal Cord 2008, 47:156-160.
    • (2008) Spinal Cord , vol.47 , pp. 156-160
    • Guizar-Sahagun, G.1    Rodriguez-Balderas, C.A.2    Franco-Bourland, R.E.3
  • 92
    • 0028143441 scopus 로고
    • Key role for pregnenolone in combination therapy that promotes recovery after spinal cord injury
    • Guth L., Zhang Z., Roberts E. Key role for pregnenolone in combination therapy that promotes recovery after spinal cord injury. Proc Natl Acad Sci U S A 1994, 91:12308-12312.
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 12308-12312
    • Guth, L.1    Zhang, Z.2    Roberts, E.3
  • 93
    • 0033394447 scopus 로고    scopus 로고
    • Is indomethacin harmful in spinal cord injury treatment? An experimental study
    • Guven M.B., Cirak B., Yuceer N., et al. Is indomethacin harmful in spinal cord injury treatment? An experimental study. Pediatr Neurosurg 1999, 31:189-193.
    • (1999) Pediatr Neurosurg , vol.31 , pp. 189-193
    • Guven, M.B.1    Cirak, B.2    Yuceer, N.3
  • 94
    • 0031930026 scopus 로고    scopus 로고
    • GM1 ganglioside: in vivo and in vitro trophic actions on central neurotransmitter systems
    • Hadjiconstantinou M., Neff N.H. GM1 ganglioside: in vivo and in vitro trophic actions on central neurotransmitter systems. J Neurochem 1998, 70:1335-1345.
    • (1998) J Neurochem , vol.70 , pp. 1335-1345
    • Hadjiconstantinou, M.1    Neff, N.H.2
  • 95
    • 0025038287 scopus 로고
    • Hypoxia-induced neurotransmitter deficits in neonatal rats are partially corrected by exogenous GM1 ganglioside
    • Hadjiconstantinou M., Yates A.J., Neff N.H. Hypoxia-induced neurotransmitter deficits in neonatal rats are partially corrected by exogenous GM1 ganglioside. J Neurochem 1990, 55:864-869.
    • (1990) J Neurochem , vol.55 , pp. 864-869
    • Hadjiconstantinou, M.1    Yates, A.J.2    Neff, N.H.3
  • 96
    • 0036490533 scopus 로고    scopus 로고
    • Pharmacological therapy after acute cervical spinal cord injury
    • Hadley M.N. Pharmacological therapy after acute cervical spinal cord injury. Neurosurgery 2002, 50:S63-S72.
    • (2002) Neurosurgery , vol.50
    • Hadley, M.N.1
  • 97
    • 33646439133 scopus 로고    scopus 로고
    • Activated microglia contribute to the maintenance of chronic pain after spinal cord injury
    • Hains B.C., Waxman S.G. Activated microglia contribute to the maintenance of chronic pain after spinal cord injury. J Neurosci 2006, 26:4308-4317.
    • (2006) J Neurosci , vol.26 , pp. 4308-4317
    • Hains, B.C.1    Waxman, S.G.2
  • 98
    • 0035059610 scopus 로고    scopus 로고
    • Reduction of pathological and behavioral deficits following spinal cord contusion injury with the selective cyclooxygenase-2 inhibitor NS-398
    • Hains B.C., Yucra J.A., Hulsebosch C.E. Reduction of pathological and behavioral deficits following spinal cord contusion injury with the selective cyclooxygenase-2 inhibitor NS-398. J Neurotrauma 2001, 18:409-423.
    • (2001) J Neurotrauma , vol.18 , pp. 409-423
    • Hains, B.C.1    Yucra, J.A.2    Hulsebosch, C.E.3
  • 99
    • 0030826778 scopus 로고    scopus 로고
    • Cyclosporin A binding to mitochondrial cyclophilin inhibits the permeability transition pore and protects hearts from ischemia/reperfusion injury
    • Halestrap A.P., Connern C.P., Griffiths E.J., et al. Cyclosporin A binding to mitochondrial cyclophilin inhibits the permeability transition pore and protects hearts from ischemia/reperfusion injury. Mol Cell Biochem 1997, 174:167-172.
    • (1997) Mol Cell Biochem , vol.174 , pp. 167-172
    • Halestrap, A.P.1    Connern, C.P.2    Griffiths, E.J.3
  • 100
    • 0022921520 scopus 로고
    • Role of lipid peroxidation in post-traumatic spinal cord degeneration: a review
    • Hall E.D., Braughler J.M. Role of lipid peroxidation in post-traumatic spinal cord degeneration: a review. Cent Nerv Syst Trauma 1986, 3:281-294.
    • (1986) Cent Nerv Syst Trauma , vol.3 , pp. 281-294
    • Hall, E.D.1    Braughler, J.M.2
  • 101
    • 0022527394 scopus 로고
    • A pharmacological analysis of the pathophysiological mechanisms of posttraumatic spinal cord ischemia
    • Hall E.D., Wolf D.L. A pharmacological analysis of the pathophysiological mechanisms of posttraumatic spinal cord ischemia. J Neurosurg 1986, 64:951-961.
    • (1986) J Neurosurg , vol.64 , pp. 951-961
    • Hall, E.D.1    Wolf, D.L.2
  • 102
    • 0025266295 scopus 로고
    • Preservation of motor nerve function during early degeneration by the 21-aminosteroid anti-oxidant U74006F
    • Hall E.D., Yonkers P.A. Preservation of motor nerve function during early degeneration by the 21-aminosteroid anti-oxidant U74006F. Brain Res 1990, 513:244-247.
    • (1990) Brain Res , vol.513 , pp. 244-247
    • Hall, E.D.1    Yonkers, P.A.2
  • 103
    • 33845938843 scopus 로고    scopus 로고
    • Role of prostacyclin in the development of compression trauma-induced spinal cord injury in rats
    • Harada N., Taoka Y., Okajima K. Role of prostacyclin in the development of compression trauma-induced spinal cord injury in rats. J Neurotrauma 2006, 23:1739-1749.
    • (2006) J Neurotrauma , vol.23 , pp. 1739-1749
    • Harada, N.1    Taoka, Y.2    Okajima, K.3
  • 104
    • 0032786125 scopus 로고    scopus 로고
    • Dynorphin A (1-13) neurotoxicity in vitro: opioid and non-opioid mechanisms in mouse spinal cord neurons
    • Hauser K.F., Foldes J.K., Turbek C.S. Dynorphin A (1-13) neurotoxicity in vitro: opioid and non-opioid mechanisms in mouse spinal cord neurons. Exp Neurol 1999, 160:361-375.
    • (1999) Exp Neurol , vol.160 , pp. 361-375
    • Hauser, K.F.1    Foldes, J.K.2    Turbek, C.S.3
  • 105
    • 63849186608 scopus 로고    scopus 로고
    • Protection and repair of the injured spinal cord: a review of completed, ongoing, and planned clinical trials for acute spinal cord injury
    • Hawryluk G.W., Rowland J., Kwon B.K., et al. Protection and repair of the injured spinal cord: a review of completed, ongoing, and planned clinical trials for acute spinal cord injury. Neurosurg Focus 2008, 25:E14.
    • (2008) Neurosurg Focus , vol.25
    • Hawryluk, G.W.1    Rowland, J.2    Kwon, B.K.3
  • 106
    • 28244488983 scopus 로고    scopus 로고
    • Immunosuppression with either cyclosporine A or FK506 supports survival of transplanted fibroblasts and promotes growth of host axons into the transplant after spinal cord injury
    • Hayashi Y., Shumsky J.S., Connors T., et al. Immunosuppression with either cyclosporine A or FK506 supports survival of transplanted fibroblasts and promotes growth of host axons into the transplant after spinal cord injury. J Neurotrauma 2005, 22:1267-1281.
    • (2005) J Neurotrauma , vol.22 , pp. 1267-1281
    • Hayashi, Y.1    Shumsky, J.S.2    Connors, T.3
  • 107
    • 0029017978 scopus 로고
    • Intrathecal dynorphin-A infusion in rat spinal cord causes energy depletion, edema and neurologic dysfunction
    • Headrick J.P., Faden A.I., Vink R. Intrathecal dynorphin-A infusion in rat spinal cord causes energy depletion, edema and neurologic dysfunction. Neurochem Int 1995, 26:489-495.
    • (1995) Neurochem Int , vol.26 , pp. 489-495
    • Headrick, J.P.1    Faden, A.I.2    Vink, R.3
  • 108
    • 33645812350 scopus 로고    scopus 로고
    • Omega-3 fatty acids improve the diagnosis-related clinical outcome
    • Heller A.R., Rossler S., Litz R.J., et al. Omega-3 fatty acids improve the diagnosis-related clinical outcome. Crit Care Med 2006, 34:972-979.
    • (2006) Crit Care Med , vol.34 , pp. 972-979
    • Heller, A.R.1    Rossler, S.2    Litz, R.J.3
  • 109
    • 0034641918 scopus 로고    scopus 로고
    • The biochemistry of apoptosis
    • Hengartner M.O. The biochemistry of apoptosis. Nature 2000, 407:770-776.
    • (2000) Nature , vol.407 , pp. 770-776
    • Hengartner, M.O.1
  • 110
    • 29744459904 scopus 로고    scopus 로고
    • Alpha-linolenic acid and riluzole treatment confer cerebral protection and improve survival after focal brain ischemia
    • Heurteaux C., Laigle C., Blondeau N., et al. Alpha-linolenic acid and riluzole treatment confer cerebral protection and improve survival after focal brain ischemia. Neurosci 2006, 137:241-251.
    • (2006) Neurosci , vol.137 , pp. 241-251
    • Heurteaux, C.1    Laigle, C.2    Blondeau, N.3
  • 111
    • 53949101802 scopus 로고    scopus 로고
    • Statins decrease chondroitin sulfate proteoglycan expression and acute astrocyte activation in central nervous system injury
    • Holmberg E., Zhang S.X., Sarmiere P.D., et al. Statins decrease chondroitin sulfate proteoglycan expression and acute astrocyte activation in central nervous system injury. Exp Neurol 2008, 214:78-86.
    • (2008) Exp Neurol , vol.214 , pp. 78-86
    • Holmberg, E.1    Zhang, S.X.2    Sarmiere, P.D.3
  • 112
    • 0026510199 scopus 로고
    • Efficacy of the 21-aminosteroid U74006F in improving neurological recovery after spinal cord injury in rats
    • Holtz A., Gerdin B. Efficacy of the 21-aminosteroid U74006F in improving neurological recovery after spinal cord injury in rats. Neurol Res 1992, 14:49-52.
    • (1992) Neurol Res , vol.14 , pp. 49-52
    • Holtz, A.1    Gerdin, B.2
  • 113
    • 0022351479 scopus 로고
    • The degradation of phospholipids, formation of metabolites of arachidonic acid, and demyelination following experimental spinal cord injury
    • Horrocks L.A., Demediuk P., Saunders R.D., et al. The degradation of phospholipids, formation of metabolites of arachidonic acid, and demyelination following experimental spinal cord injury. Cent Nerv Syst Trauma 1985, 2:115-120.
    • (1985) Cent Nerv Syst Trauma , vol.2 , pp. 115-120
    • Horrocks, L.A.1    Demediuk, P.2    Saunders, R.D.3
  • 114
    • 33847029206 scopus 로고    scopus 로고
    • The characteristics of neuronal injury in a static compression model of spinal cord injury in adult rats
    • Huang W.L., George K.J., Ibba V., et al. The characteristics of neuronal injury in a static compression model of spinal cord injury in adult rats. Eur J Neurosci 2007, 25:362-372.
    • (2007) Eur J Neurosci , vol.25 , pp. 362-372
    • Huang, W.L.1    George, K.J.2    Ibba, V.3
  • 115
    • 35648944690 scopus 로고    scopus 로고
    • A combination of intravenous and dietary docosahexaenoic acid significantly improves outcome after spinal cord injury
    • Huang W.L., King V.R., Curran O.E., et al. A combination of intravenous and dietary docosahexaenoic acid significantly improves outcome after spinal cord injury. Brain 2007, 130:3004-3019.
    • (2007) Brain , vol.130 , pp. 3004-3019
    • Huang, W.L.1    King, V.R.2    Curran, O.E.3
  • 116
    • 68349106700 scopus 로고    scopus 로고
    • Arachidonyl trifluoromethyl ketone is neuroprotective after spinal cord injury
    • Huang W., Bhavsar A., Ward R.E., et al. Arachidonyl trifluoromethyl ketone is neuroprotective after spinal cord injury. J Neurotrauma 2009, 26:1429-1434.
    • (2009) J Neurotrauma , vol.26 , pp. 1429-1434
    • Huang, W.1    Bhavsar, A.2    Ward, R.E.3
  • 117
    • 13244296826 scopus 로고    scopus 로고
    • Calpain inhibitor inhibits p35-p25-Cdk5 activation, decreases tau hyperphosphorylation, and improves neurological function after spinal cord hemisection in rats
    • Hung K.S., Hwang S.L., Liang C.L., et al. Calpain inhibitor inhibits p35-p25-Cdk5 activation, decreases tau hyperphosphorylation, and improves neurological function after spinal cord hemisection in rats. J Neuropathol Exp Neurol 2005, 64:15-26.
    • (2005) J Neuropathol Exp Neurol , vol.64 , pp. 15-26
    • Hung, K.S.1    Hwang, S.L.2    Liang, C.L.3
  • 118
    • 42049104347 scopus 로고    scopus 로고
    • Methylprednisolone for acute spinal cord injury: 5-year practice reversal
    • Hurlbert R.J., Hamilton M.G. Methylprednisolone for acute spinal cord injury: 5-year practice reversal. Can J Neurol Sci 2008, 35:41-45.
    • (2008) Can J Neurol Sci , vol.35 , pp. 41-45
    • Hurlbert, R.J.1    Hamilton, M.G.2
  • 119
    • 33748539336 scopus 로고    scopus 로고
    • Protective effect of cyclosporin-A in spinal cord injury: an overview
    • Ibarra A., Diaz-Ruiz A. Protective effect of cyclosporin-A in spinal cord injury: an overview. Curr Med Chem 2006, 13:2703-2710.
    • (2006) Curr Med Chem , vol.13 , pp. 2703-2710
    • Ibarra, A.1    Diaz-Ruiz, A.2
  • 120
    • 0033616414 scopus 로고    scopus 로고
    • The role of voltage-gated Ca2+ channels in anoxic injury of spinal cord white matter
    • Imaizumi T., Kocsis J.D., Waxman S.G. The role of voltage-gated Ca2+ channels in anoxic injury of spinal cord white matter. Brain Res 1999, 817:84-92.
    • (1999) Brain Res , vol.817 , pp. 84-92
    • Imaizumi, T.1    Kocsis, J.D.2    Waxman, S.G.3
  • 121
    • 0037447806 scopus 로고    scopus 로고
    • Induced hypothermia in experimental traumatic spinal cord injury: an update
    • Inamasu J., Nakamura Y., Ichikizaki K. Induced hypothermia in experimental traumatic spinal cord injury: an update. J Neurol Sci 2003, 209:55-60.
    • (2003) J Neurol Sci , vol.209 , pp. 55-60
    • Inamasu, J.1    Nakamura, Y.2    Ichikizaki, K.3
  • 122
    • 0034255402 scopus 로고    scopus 로고
    • Effects of core body temperature on changes in spinal somatosensory-evoked potential in acute spinal cord compression injury: an experimental study in the rat
    • Jou I.M. Effects of core body temperature on changes in spinal somatosensory-evoked potential in acute spinal cord compression injury: an experimental study in the rat. Spine 2000, 25:1878-1885.
    • (2000) Spine , vol.25 , pp. 1878-1885
    • Jou, I.M.1
  • 123
    • 0033139737 scopus 로고    scopus 로고
    • A review of the neuropathology of human spinal cord injury with emphasis on special features
    • Kakulas B.A. A review of the neuropathology of human spinal cord injury with emphasis on special features. J Spinal Cord Med 1999, 22:119-124.
    • (1999) J Spinal Cord Med , vol.22 , pp. 119-124
    • Kakulas, B.A.1
  • 124
    • 0033001836 scopus 로고    scopus 로고
    • The applied neuropathology of human spinal cord injury
    • Kakulas B.A. The applied neuropathology of human spinal cord injury. Spinal Cord 1999, 37:79-88.
    • (1999) Spinal Cord , vol.37 , pp. 79-88
    • Kakulas, B.A.1
  • 125
    • 57149093203 scopus 로고    scopus 로고
    • FKBP family proteins: immunophilins with versatile biological functions
    • Kang C.B., Hong Y., Dhe-Paganon S., et al. FKBP family proteins: immunophilins with versatile biological functions. Neurosignals 2008, 16:318-325.
    • (2008) Neurosignals , vol.16 , pp. 318-325
    • Kang, C.B.1    Hong, Y.2    Dhe-Paganon, S.3
  • 126
    • 22444436580 scopus 로고    scopus 로고
    • Leukemia inhibitory factor promotes oligodendrocyte survival after spinal cord injury
    • Kerr B.J., Patterson P.H. Leukemia inhibitory factor promotes oligodendrocyte survival after spinal cord injury. Glia 2005, 51:73-79.
    • (2005) Glia , vol.51 , pp. 73-79
    • Kerr, B.J.1    Patterson, P.H.2
  • 127
    • 9644299706 scopus 로고    scopus 로고
    • A novel endogenous erythropoietin mediated pathway prevents axonal degeneration
    • Keswani S.C., Buldanlioglu U., Fischer A., et al. A novel endogenous erythropoietin mediated pathway prevents axonal degeneration. Ann Neurol 2004, 56:815-826.
    • (2004) Ann Neurol , vol.56 , pp. 815-826
    • Keswani, S.C.1    Buldanlioglu, U.2    Fischer, A.3
  • 128
    • 70350558453 scopus 로고    scopus 로고
    • Identification of two distinct macrophage subsets with divergent effects causing either neurotoxicity or regeneration in the injured mouse spinal cord
    • Kigerl K.A., Gensel J.C., Ankeny D.P., et al. Identification of two distinct macrophage subsets with divergent effects causing either neurotoxicity or regeneration in the injured mouse spinal cord. J Neurosci 2009, 29:13435-13444.
    • (2009) J Neurosci , vol.29 , pp. 13435-13444
    • Kigerl, K.A.1    Gensel, J.C.2    Ankeny, D.P.3
  • 129
    • 84867789433 scopus 로고    scopus 로고
    • Pathology of non-neoplastic, regional disorders of the spinal cord
    • Oxford University Press, Oxford, J.S. Nelson, H. Mena, J.E. Parisi (Eds.)
    • Kim R.C. Pathology of non-neoplastic, regional disorders of the spinal cord. Principles and Practice of Neuropathology 2003, 459-496. Oxford University Press, Oxford. J.S. Nelson, H. Mena, J.E. Parisi (Eds.).
    • (2003) Principles and Practice of Neuropathology , pp. 459-496
    • Kim, R.C.1
  • 130
    • 33646844063 scopus 로고    scopus 로고
    • Omega-3 fatty acids improve recovery, whereas omega-6 fatty acids worsen outcome, after spinal cord injury in the adult rat
    • King V.R., Huang W.L., Dyall S.C., et al. Omega-3 fatty acids improve recovery, whereas omega-6 fatty acids worsen outcome, after spinal cord injury in the adult rat. J Neurosci 2006, 26:4672-4680.
    • (2006) J Neurosci , vol.26 , pp. 4672-4680
    • King, V.R.1    Huang, W.L.2    Dyall, S.C.3
  • 131
    • 3042670289 scopus 로고    scopus 로고
    • Resveratrol, a red wine polyphenol, protects spinal cord from ischemia-reperfusion injury
    • Kiziltepe U., Turan N.N., Han U., et al. Resveratrol, a red wine polyphenol, protects spinal cord from ischemia-reperfusion injury. J Vasc Surg 2004, 40:138-145.
    • (2004) J Vasc Surg , vol.40 , pp. 138-145
    • Kiziltepe, U.1    Turan, N.N.2    Han, U.3
  • 132
    • 0027530177 scopus 로고
    • Silicone rubber microangiography of acute spinal cord injury in the rat
    • Koyanagi I., Tator C.H., Theriault E. Silicone rubber microangiography of acute spinal cord injury in the rat. Neurosurgery 1993, 32:260-268.
    • (1993) Neurosurgery , vol.32 , pp. 260-268
    • Koyanagi, I.1    Tator, C.H.2    Theriault, E.3
  • 133
    • 0034465558 scopus 로고    scopus 로고
    • Effects of dexamethasone and of local hypothermia on early and late tissue electrolyte changes in experimental spinal cord injury
    • Kuchner E.F., Hansebout R.R., Pappius H.M. Effects of dexamethasone and of local hypothermia on early and late tissue electrolyte changes in experimental spinal cord injury. J Spinal Disord 2000, 13:391-398.
    • (2000) J Spinal Disord , vol.13 , pp. 391-398
    • Kuchner, E.F.1    Hansebout, R.R.2    Pappius, H.M.3
  • 134
    • 60649089249 scopus 로고    scopus 로고
    • Neuroprotective effects of infliximab in experimental spinal cord injury
    • Kurt G., Ergun E., Cemil B., et al. Neuroprotective effects of infliximab in experimental spinal cord injury. Surg Neurol 2009, 71:332-336.
    • (2009) Surg Neurol , vol.71 , pp. 332-336
    • Kurt, G.1    Ergun, E.2    Cemil, B.3
  • 135
    • 3342967871 scopus 로고    scopus 로고
    • Pathophysiology and pharmacologic treatment of acute spinal cord injury
    • Kwon B.K., Tetzlaff W., Grauer J.N., et al. Pathophysiology and pharmacologic treatment of acute spinal cord injury. Spine J 2004, 4:451-464.
    • (2004) Spine J , vol.4 , pp. 451-464
    • Kwon, B.K.1    Tetzlaff, W.2    Grauer, J.N.3
  • 136
    • 54849408212 scopus 로고    scopus 로고
    • Hypothermia for spinal cord injury
    • Kwon B.K., Mann C., Sohn H.M., et al. Hypothermia for spinal cord injury. Spine J 2008, 8:859-874.
    • (2008) Spine J , vol.8 , pp. 859-874
    • Kwon, B.K.1    Mann, C.2    Sohn, H.M.3
  • 137
    • 67649982189 scopus 로고    scopus 로고
    • Effects of progesterone on oligodendrocyte progenitors, oligodendrocyte transcription factors, and myelin proteins following spinal cord injury
    • Labombarda F., Gonzalez S.L., Lima A., et al. Effects of progesterone on oligodendrocyte progenitors, oligodendrocyte transcription factors, and myelin proteins following spinal cord injury. Glia 2009, 57:884-897.
    • (2009) Glia , vol.57 , pp. 884-897
    • Labombarda, F.1    Gonzalez, S.L.2    Lima, A.3
  • 138
    • 0034235577 scopus 로고    scopus 로고
    • Prevention of ischemic spinal cord injury: comparative effects of magnesium sulfate and riluzole
    • Lang-Lazdunski L., Heurteaux C., Dupont H., et al. Prevention of ischemic spinal cord injury: comparative effects of magnesium sulfate and riluzole. J Vasc Surg 2000, 32:179-189.
    • (2000) J Vasc Surg , vol.32 , pp. 179-189
    • Lang-Lazdunski, L.1    Heurteaux, C.2    Dupont, H.3
  • 139
    • 0141835805 scopus 로고    scopus 로고
    • Linolenic acid prevents neuronal cell death and paraplegia after transient spinal cord ischemia in rats
    • Lang-Lazdunski L., Blondeau N., Jarretou G., et al. Linolenic acid prevents neuronal cell death and paraplegia after transient spinal cord ischemia in rats. J Vasc Surg 2003, 38:564-575.
    • (2003) J Vasc Surg , vol.38 , pp. 564-575
    • Lang-Lazdunski, L.1    Blondeau, N.2    Jarretou, G.3
  • 140
    • 43049168863 scopus 로고    scopus 로고
    • No evidence for chronic demyelination in spared axons after spinal cord injury in a mouse
    • Lasiene J., Shupe L., Perlmutter S., et al. No evidence for chronic demyelination in spared axons after spinal cord injury in a mouse. J Neurosci 2008, 28:3887-3896.
    • (2008) J Neurosci , vol.28 , pp. 3887-3896
    • Lasiene, J.1    Shupe, L.2    Perlmutter, S.3
  • 141
    • 0034678889 scopus 로고    scopus 로고
    • Polyunsaturated fatty acids are potent neuroprotectors
    • Lauritzen I., Blondeau N., Heurteaux C., et al. Polyunsaturated fatty acids are potent neuroprotectors. EMBO J 2000, 19:1784-1793.
    • (2000) EMBO J , vol.19 , pp. 1784-1793
    • Lauritzen, I.1    Blondeau, N.2    Heurteaux, C.3
  • 142
    • 0033964038 scopus 로고    scopus 로고
    • Cytokine chemokine expression in contused rat spinal cord
    • Lee Y.L., Shih K., Bao P., et al. Cytokine chemokine expression in contused rat spinal cord. Neurochem Int 2000, 36:417-425.
    • (2000) Neurochem Int , vol.36 , pp. 417-425
    • Lee, Y.L.1    Shih, K.2    Bao, P.3
  • 143
    • 0142025464 scopus 로고    scopus 로고
    • Minocycline reduces cell death and improves functional recovery after traumatic spinal cord injury in the rat
    • Lee S.M., Yune T.Y., Kim S.J., et al. Minocycline reduces cell death and improves functional recovery after traumatic spinal cord injury in the rat. J Neurotrauma 2003, 20:1017-1027.
    • (2003) J Neurotrauma , vol.20 , pp. 1017-1027
    • Lee, S.M.1    Yune, T.Y.2    Kim, S.J.3
  • 144
    • 3042725549 scopus 로고    scopus 로고
    • Derivatives of erythropoietin that are tissue protective but not erythropoietic
    • Leist M., Ghezzi P., Grasso G., et al. Derivatives of erythropoietin that are tissue protective but not erythropoietic. Science 2004, 305:239-242.
    • (2004) Science , vol.305 , pp. 239-242
    • Leist, M.1    Ghezzi, P.2    Grasso, G.3
  • 145
    • 0025907224 scopus 로고
    • Excitatory amino acids rise to toxic levels upon impact injury to the rat spinal cord
    • Liu D., Thangnipon W., McAdoo D.J. Excitatory amino acids rise to toxic levels upon impact injury to the rat spinal cord. Brain Res 1991, 547:344-348.
    • (1991) Brain Res , vol.547 , pp. 344-348
    • Liu, D.1    Thangnipon, W.2    McAdoo, D.J.3
  • 146
    • 16944363478 scopus 로고    scopus 로고
    • Neuronal and glial apoptosis after traumatic spinal cord injury
    • Liu X.Z., Xu X.M., Hu R., et al. Neuronal and glial apoptosis after traumatic spinal cord injury. J Neurosci 1997, 17:5395-5406.
    • (1997) J Neurosci , vol.17 , pp. 5395-5406
    • Liu, X.Z.1    Xu, X.M.2    Hu, R.3
  • 147
    • 2342613518 scopus 로고    scopus 로고
    • Antioxidation of melatonin against spinal cord injury in rats
    • Liu J.B., Tang T.S., Yang H.L., et al. Antioxidation of melatonin against spinal cord injury in rats. Chin Med J (Engl) 2004, 117:571-575.
    • (2004) Chin Med J (Engl) , vol.117 , pp. 571-575
    • Liu, J.B.1    Tang, T.S.2    Yang, H.L.3
  • 148
    • 66149096703 scopus 로고    scopus 로고
    • Systemic hypothermia improves histological and functional outcome after cervical spinal cord contusion in rats
    • Lo T.P., Cho K.S., Garg M.S., et al. Systemic hypothermia improves histological and functional outcome after cervical spinal cord contusion in rats. J Comp Neurol 2009, 514:433-448.
    • (2009) J Comp Neurol , vol.514 , pp. 433-448
    • Lo, T.P.1    Cho, K.S.2    Garg, M.S.3
  • 149
    • 27444436221 scopus 로고    scopus 로고
    • FK 506 reduces tissue damage and prevents functional deficit after spinal cord injury in the rat
    • Lopez-Vales R., Garcia-Alias G., Fores J., et al. FK 506 reduces tissue damage and prevents functional deficit after spinal cord injury in the rat. J Neurosci Res 2005, 81:827-836.
    • (2005) J Neurosci Res , vol.81 , pp. 827-836
    • Lopez-Vales, R.1    Garcia-Alias, G.2    Fores, J.3
  • 150
    • 33750824777 scopus 로고    scopus 로고
    • Olfactory ensheathing glia graft in combination with FK506 administration promote repair after spinal cord injury
    • Lopez-Vales R., Fores J., Navarro X., et al. Olfactory ensheathing glia graft in combination with FK506 administration promote repair after spinal cord injury. Neurobiol Dis 2006, 24:443-454.
    • (2006) Neurobiol Dis , vol.24 , pp. 443-454
    • Lopez-Vales, R.1    Fores, J.2    Navarro, X.3
  • 151
    • 33646592866 scopus 로고    scopus 로고
    • Effects of COX-2 and iNOS inhibitors alone or in combination with olfactory ensheathing cell grafts after spinal cord injury
    • Lopez-Vales R., Garcia-Alias G., Guzman-Lenis M.S., et al. Effects of COX-2 and iNOS inhibitors alone or in combination with olfactory ensheathing cell grafts after spinal cord injury. Spine 2006, 31:1100-1106.
    • (2006) Spine , vol.31 , pp. 1100-1106
    • Lopez-Vales, R.1    Garcia-Alias, G.2    Guzman-Lenis, M.S.3
  • 152
    • 0031783704 scopus 로고    scopus 로고
    • Apoptosis as a mechanism of neuronal cell death following acute experimental spinal cord injury
    • Lou J., Lenke L.G., Ludwig F.J., et al. Apoptosis as a mechanism of neuronal cell death following acute experimental spinal cord injury. Spinal Cord 1998, 36:683-690.
    • (1998) Spinal Cord , vol.36 , pp. 683-690
    • Lou, J.1    Lenke, L.G.2    Ludwig, F.J.3
  • 153
    • 0029804767 scopus 로고    scopus 로고
    • Cyclosporine induces neuronal apoptosis and selective oligodendrocyte death in cortical cultures
    • McDonald J.W., Goldberg M.P., Gwag B.J., et al. Cyclosporine induces neuronal apoptosis and selective oligodendrocyte death in cortical cultures. Ann Neurol 1996, 40:750-758.
    • (1996) Ann Neurol , vol.40 , pp. 750-758
    • McDonald, J.W.1    Goldberg, M.P.2    Gwag, B.J.3
  • 154
    • 34248598448 scopus 로고    scopus 로고
    • The PPAR gamma agonist pioglitazone improves anatomical and locomotor recovery after rodent spinal cord injury
    • McTigue D.M., Tripathi R., Wei P., et al. The PPAR gamma agonist pioglitazone improves anatomical and locomotor recovery after rodent spinal cord injury. Exp Neurol 2007, 205:396-406.
    • (2007) Exp Neurol , vol.205 , pp. 396-406
    • McTigue, D.M.1    Tripathi, R.2    Wei, P.3
  • 155
    • 0032411557 scopus 로고    scopus 로고
    • Tacrolimus (FK506) increases neuronal expression of GAP-43 and improves functional recovery after spinal cord injury in rats
    • Madsen J.R., MacDonald P., Irwin N., et al. Tacrolimus (FK506) increases neuronal expression of GAP-43 and improves functional recovery after spinal cord injury in rats. Exp Neurol 1998, 154:673-683.
    • (1998) Exp Neurol , vol.154 , pp. 673-683
    • Madsen, J.R.1    MacDonald, P.2    Irwin, N.3
  • 156
    • 42749096105 scopus 로고    scopus 로고
    • Delayed treatment of spinal cord injury with erythropoietin or darbepoetin-a lack of neuroprotective efficacy in a contusion model of cord injury
    • Mann C., Lee J.H., Liu J., et al. Delayed treatment of spinal cord injury with erythropoietin or darbepoetin-a lack of neuroprotective efficacy in a contusion model of cord injury. Exp Neurol 2008, 211:34-40.
    • (2008) Exp Neurol , vol.211 , pp. 34-40
    • Mann, C.1    Lee, J.H.2    Liu, J.3
  • 157
    • 73949139517 scopus 로고    scopus 로고
    • Lack of robust neurologic benefits with simvastatin or atorvastatin treatment after acute thoracic spinal cord contusion injury
    • Mann C.M., Lee J.H., Hillyer J., et al. Lack of robust neurologic benefits with simvastatin or atorvastatin treatment after acute thoracic spinal cord contusion injury. Exp Neurol 2010, 221:285-295.
    • (2010) Exp Neurol , vol.221 , pp. 285-295
    • Mann, C.M.1    Lee, J.H.2    Hillyer, J.3
  • 158
    • 33751093803 scopus 로고    scopus 로고
    • Re-evaluation of mitochondrial permeability transition as a primary neuroprotective target of minocycline
    • Mansson R., Hansson M.J., Morota S., et al. Re-evaluation of mitochondrial permeability transition as a primary neuroprotective target of minocycline. Neurobiol Dis 2007, 25:198-205.
    • (2007) Neurobiol Dis , vol.25 , pp. 198-205
    • Mansson, R.1    Hansson, M.J.2    Morota, S.3
  • 159
    • 67649159074 scopus 로고    scopus 로고
    • Effects of etanercept and minocycline in a rat model of spinal cord injury
    • Marchand F., Tsantoulas C., Singh D., et al. Effects of etanercept and minocycline in a rat model of spinal cord injury. Eur J Pain 2009, 13:673-681.
    • (2009) Eur J Pain , vol.13 , pp. 673-681
    • Marchand, F.1    Tsantoulas, C.2    Singh, D.3
  • 160
    • 0034672081 scopus 로고    scopus 로고
    • Docosahexaenoic acid, a ligand for the retinoid X receptor in mouse brain
    • Mata de Urquiza A., Liu S., Sjoberg M., et al. Docosahexaenoic acid, a ligand for the retinoid X receptor in mouse brain. Science 2000, 290:2140-2144.
    • (2000) Science , vol.290 , pp. 2140-2144
    • Mata de Urquiza, A.1    Liu, S.2    Sjoberg, M.3
  • 161
    • 33644652740 scopus 로고    scopus 로고
    • Involvement of PPAR nuclear receptors in tissue injury and wound repair
    • Michalik L., Wahli W. Involvement of PPAR nuclear receptors in tissue injury and wound repair. J Clin Invest 2006, 116:598-606.
    • (2006) J Clin Invest , vol.116 , pp. 598-606
    • Michalik, L.1    Wahli, W.2
  • 162
    • 0642340405 scopus 로고    scopus 로고
    • Role of calcineurin in calcium-mediated hypoxic injury to white matter
    • Mobley L.W., Agrawal S.K. Role of calcineurin in calcium-mediated hypoxic injury to white matter. Spine J 2003, 3:11-18.
    • (2003) Spine J , vol.3 , pp. 11-18
    • Mobley, L.W.1    Agrawal, S.K.2
  • 163
    • 9744242678 scopus 로고    scopus 로고
    • Omega-3 fatty acids and inflammation
    • Mori T.A., Beilin L.J. Omega-3 fatty acids and inflammation. Curr Atheroscler Rep 2004, 6:461-467.
    • (2004) Curr Atheroscler Rep , vol.6 , pp. 461-467
    • Mori, T.A.1    Beilin, L.J.2
  • 164
    • 0035836469 scopus 로고    scopus 로고
    • Changes in axonal physiology and morphology after chronic compressive injury of the rat thoracic spinal cord
    • Nashmi R., Fehlings M.G. Changes in axonal physiology and morphology after chronic compressive injury of the rat thoracic spinal cord. Neurosci 2001, 104:235-251.
    • (2001) Neurosci , vol.104 , pp. 235-251
    • Nashmi, R.1    Fehlings, M.G.2
  • 165
    • 42449119205 scopus 로고    scopus 로고
    • Aquaporin 1 - a novel player in spinal cord injury
    • Nesic O., Lee J., Unabia G.C., et al. Aquaporin 1 - a novel player in spinal cord injury. J Neurochem 2008, 105:628-640.
    • (2008) J Neurochem , vol.105 , pp. 628-640
    • Nesic, O.1    Lee, J.2    Unabia, G.C.3
  • 166
    • 33845288983 scopus 로고    scopus 로고
    • Delayed riluzole treatment is able to rescue injured rat spinal motoneurons
    • Nogradi A., Szabo A., Pinter S., et al. Delayed riluzole treatment is able to rescue injured rat spinal motoneurons. Neurosci 2007, 144:431-438.
    • (2007) Neurosci , vol.144 , pp. 431-438
    • Nogradi, A.1    Szabo, A.2    Pinter, S.3
  • 167
    • 1942425481 scopus 로고    scopus 로고
    • The pathology of human spinal cord injury: defining the problems
    • Norenberg M.D., Smith J., Marcillo A. The pathology of human spinal cord injury: defining the problems. J Neurotrauma 2004, 21:429-440.
    • (2004) J Neurotrauma , vol.21 , pp. 429-440
    • Norenberg, M.D.1    Smith, J.2    Marcillo, A.3
  • 168
    • 0036435516 scopus 로고    scopus 로고
    • FK506 treatment inhibits caspase-3 activation and promotes oligodendroglial survival following traumatic spinal cord injury
    • Nottingham S., Knapp P., Springer J. FK506 treatment inhibits caspase-3 activation and promotes oligodendroglial survival following traumatic spinal cord injury. Exp Neurol 2002, 177:242-251.
    • (2002) Exp Neurol , vol.177 , pp. 242-251
    • Nottingham, S.1    Knapp, P.2    Springer, J.3
  • 169
    • 12744277932 scopus 로고    scopus 로고
    • Anti-CD11d integrin antibody treatment restores normal serotonergic projections to the dorsal, intermediate, and ventral horns of the injured spinal cord
    • Oatway M.A., Chen Y., Bruce J.C., et al. Anti-CD11d integrin antibody treatment restores normal serotonergic projections to the dorsal, intermediate, and ventral horns of the injured spinal cord. J Neurosci 2005, 25:637-647.
    • (2005) J Neurosci , vol.25 , pp. 637-647
    • Oatway, M.A.1    Chen, Y.2    Bruce, J.C.3
  • 170
    • 33644818304 scopus 로고    scopus 로고
    • 1,026 experimental treatments in acute stroke
    • O'Collins V.E., Macleod M.R., Donnan G.A., et al. 1,026 experimental treatments in acute stroke. Ann Neurol 2006, 59:467-477.
    • (2006) Ann Neurol , vol.59 , pp. 467-477
    • O'Collins, V.E.1    Macleod, M.R.2    Donnan, G.A.3
  • 171
    • 33646521959 scopus 로고    scopus 로고
    • Effects of cyclosporin a on neurological outcome and serum biomarkers in the same setting of spinal cord ischemia model
    • Ozkisacik E.A., Discigil B., Boga M., et al. Effects of cyclosporin a on neurological outcome and serum biomarkers in the same setting of spinal cord ischemia model. Ann Vasc Surg 2006, 20:243-249.
    • (2006) Ann Vasc Surg , vol.20 , pp. 243-249
    • Ozkisacik, E.A.1    Discigil, B.2    Boga, M.3
  • 172
    • 33947287850 scopus 로고    scopus 로고
    • Post-trauma Lipitor treatment prevents endothelial dysfunction, facilitates neuroprotection, and promotes locomotor recovery following spinal cord injury
    • Pannu R., Christie D.K., Barbosa E., et al. Post-trauma Lipitor treatment prevents endothelial dysfunction, facilitates neuroprotection, and promotes locomotor recovery following spinal cord injury. J Neurochem 2007, 101:182-200.
    • (2007) J Neurochem , vol.101 , pp. 182-200
    • Pannu, R.1    Christie, D.K.2    Barbosa, E.3
  • 173
    • 0025162091 scopus 로고
    • Alteration in extracellular amino acids after traumatic spinal cord injury
    • Panter S.S., Yum S.W., Faden A.I. Alteration in extracellular amino acids after traumatic spinal cord injury. Ann Neurol 1990, 27:96-99.
    • (1990) Ann Neurol , vol.27 , pp. 96-99
    • Panter, S.S.1    Yum, S.W.2    Faden, A.I.3
  • 174
    • 24944563984 scopus 로고    scopus 로고
    • Effect of indomethacin on motor activity and spinal cord free fatty acid content after experimental spinal cord injury in rabbits
    • Pantovic R., Draganic P., Erakovic V., et al. Effect of indomethacin on motor activity and spinal cord free fatty acid content after experimental spinal cord injury in rabbits. Spinal Cord 2005, 43:519-526.
    • (2005) Spinal Cord , vol.43 , pp. 519-526
    • Pantovic, R.1    Draganic, P.2    Erakovic, V.3
  • 175
    • 33847093475 scopus 로고    scopus 로고
    • Thiazolidinedione class of peroxisome proliferator-activated receptor gamma agonists prevents neuronal damage, motor dysfunction, myelin loss, neuropathic pain, and inflammation after spinal cord injury in adult rats
    • Park S.W., Yi J.H., Miranpuri G., et al. Thiazolidinedione class of peroxisome proliferator-activated receptor gamma agonists prevents neuronal damage, motor dysfunction, myelin loss, neuropathic pain, and inflammation after spinal cord injury in adult rats. J Pharmacol Exp Ther 2007, 320:1002-1012.
    • (2007) J Pharmacol Exp Ther , vol.320 , pp. 1002-1012
    • Park, S.W.1    Yi, J.H.2    Miranpuri, G.3
  • 176
    • 33646379090 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha contributes to below-level neuropathic pain after spinal cord injury
    • Peng X.M., Zhou Z.G., Glorioso J.C., et al. Tumor necrosis factor-alpha contributes to below-level neuropathic pain after spinal cord injury. Ann Neurol 2006, 59:843-851.
    • (2006) Ann Neurol , vol.59 , pp. 843-851
    • Peng, X.M.1    Zhou, Z.G.2    Glorioso, J.C.3
  • 177
    • 0035869332 scopus 로고    scopus 로고
    • Resting murine neutrophils express functional alpha 4 integrins that signal through Src family kinases
    • Pereira S., Zhou M., Mocsai A., et al. Resting murine neutrophils express functional alpha 4 integrins that signal through Src family kinases. J Immunol 2001, 166:4115-4123.
    • (2001) J Immunol , vol.166 , pp. 4115-4123
    • Pereira, S.1    Zhou, M.2    Mocsai, A.3
  • 178
    • 49449094589 scopus 로고    scopus 로고
    • A re-assessment of erythropoietin as a neuroprotective agent following rat spinal cord compression or contusion injury
    • Pinzon A., Marcillo A., Pabon D., et al. A re-assessment of erythropoietin as a neuroprotective agent following rat spinal cord compression or contusion injury. Exp Neurol 2008, 213:129-136.
    • (2008) Exp Neurol , vol.213 , pp. 129-136
    • Pinzon, A.1    Marcillo, A.2    Pabon, D.3
  • 179
    • 55649088905 scopus 로고    scopus 로고
    • A re-assessment of minocycline as a neuroprotective agent in a rat spinal cord contusion model
    • Pinzon A., Marcillo A., Quintana A., et al. A re-assessment of minocycline as a neuroprotective agent in a rat spinal cord contusion model. Brain Res 2008, 1243:146-151.
    • (2008) Brain Res , vol.1243 , pp. 146-151
    • Pinzon, A.1    Marcillo, A.2    Quintana, A.3
  • 180
    • 49349093001 scopus 로고    scopus 로고
    • Dietary restriction started after spinal cord injury improves functional recovery
    • Plunet W.T., Streijger F., Lam C.K., et al. Dietary restriction started after spinal cord injury improves functional recovery. Exp Neurol 2008, 213:28-35.
    • (2008) Exp Neurol , vol.213 , pp. 28-35
    • Plunet, W.T.1    Streijger, F.2    Lam, C.K.3
  • 181
    • 0031013236 scopus 로고    scopus 로고
    • Cellular inflammatory response after spinal cord injury in Sprague-Dawley and Lewis rats
    • Popovich P.G., Wei P., Stokes B.T. Cellular inflammatory response after spinal cord injury in Sprague-Dawley and Lewis rats. J Comp Neurol 1997, 377:443-464.
    • (1997) J Comp Neurol , vol.377 , pp. 443-464
    • Popovich, P.G.1    Wei, P.2    Stokes, B.T.3
  • 182
    • 0032838089 scopus 로고    scopus 로고
    • Depletion of hematogenous macrophages promotes partial hindlimb recovery and neuroanatomical repair after experimental spinal cord injury
    • Popovich P.G., Guan Z., Wei P., et al. Depletion of hematogenous macrophages promotes partial hindlimb recovery and neuroanatomical repair after experimental spinal cord injury. Exp Neurol 1999, 158:351-365.
    • (1999) Exp Neurol , vol.158 , pp. 351-365
    • Popovich, P.G.1    Guan, Z.2    Wei, P.3
  • 183
    • 1842419475 scopus 로고    scopus 로고
    • Degenerative and regenerative mechanisms governing spinal cord injury
    • Profyris C., Cheema S.S., Zang D., et al. Degenerative and regenerative mechanisms governing spinal cord injury. Neurobiol Dis 2004, 15:415-436.
    • (2004) Neurobiol Dis , vol.15 , pp. 415-436
    • Profyris, C.1    Cheema, S.S.2    Zang, D.3
  • 184
    • 48749127781 scopus 로고    scopus 로고
    • GM1 ganglioside contributes to retain the neuronal conduction and neuronal excitability in visceral and baroreceptor afferents
    • Qiao G.F., Cheng Z.F., Huo R., et al. GM1 ganglioside contributes to retain the neuronal conduction and neuronal excitability in visceral and baroreceptor afferents. J Neurochem 2008, 106:1637-1645.
    • (2008) J Neurochem , vol.106 , pp. 1637-1645
    • Qiao, G.F.1    Cheng, Z.F.2    Huo, R.3
  • 185
    • 0035008642 scopus 로고    scopus 로고
    • Cyclosporin A treatment following spinal cord injury to the rat: behavioral effects and stereological assessment of tissue sparing
    • Rabchevsky A.G., Fugaccia I., Sullivan P.G., et al. Cyclosporin A treatment following spinal cord injury to the rat: behavioral effects and stereological assessment of tissue sparing. J Neurotrauma 2001, 18:513-522.
    • (2001) J Neurotrauma , vol.18 , pp. 513-522
    • Rabchevsky, A.G.1    Fugaccia, I.2    Sullivan, P.G.3
  • 186
    • 27744537884 scopus 로고    scopus 로고
    • Septations in chronic spinal cord injury cavities contain axons
    • Radojicic M., Reier P.J., Steward O., et al. Septations in chronic spinal cord injury cavities contain axons. Exp Neurol 2005, 196:339-341.
    • (2005) Exp Neurol , vol.196 , pp. 339-341
    • Radojicic, M.1    Reier, P.J.2    Steward, O.3
  • 187
    • 38849181802 scopus 로고    scopus 로고
    • Nuclear factor-kappaB decoy amelioration of spinal cord injury-induced inflammation and behavior outcomes
    • Rafati D.S., Geissler K., Johnson K., et al. Nuclear factor-kappaB decoy amelioration of spinal cord injury-induced inflammation and behavior outcomes. J Neurosci Res 2008, 86:566-580.
    • (2008) J Neurosci Res , vol.86 , pp. 566-580
    • Rafati, D.S.1    Geissler, K.2    Johnson, K.3
  • 188
    • 35648942661 scopus 로고    scopus 로고
    • Post-treatment with the cyclosporin derivative, NIM811, reduced indices of cell death and increased the volume of spared tissue in the acute period following spinal cord contusion
    • Ravikumar R., McEwen M.L., Springer J.E. Post-treatment with the cyclosporin derivative, NIM811, reduced indices of cell death and increased the volume of spared tissue in the acute period following spinal cord contusion. J Neurotrauma 2007, 24:1618-1630.
    • (2007) J Neurotrauma , vol.24 , pp. 1618-1630
    • Ravikumar, R.1    McEwen, M.L.2    Springer, J.E.3
  • 189
    • 0037989744 scopus 로고    scopus 로고
    • Calpain in the pathophysiology of spinal cord injury: neuroprotection with calpain inhibitors
    • Ray S.K., Hogan E.L., Banik N.L. Calpain in the pathophysiology of spinal cord injury: neuroprotection with calpain inhibitors. Brain Res Rev 2003, 42:169-185.
    • (2003) Brain Res Rev , vol.42 , pp. 169-185
    • Ray, S.K.1    Hogan, E.L.2    Banik, N.L.3
  • 190
    • 38149140283 scopus 로고    scopus 로고
    • Melatonin defeats neurally-derived free radicals and reduces the associated neuromorphological and neurobehavioral damage
    • Reiter R.J., Tan D.X., Manchester L.C., et al. Melatonin defeats neurally-derived free radicals and reduces the associated neuromorphological and neurobehavioral damage. J Physiol Pharmacol 2007, 58:5-22.
    • (2007) J Physiol Pharmacol , vol.58 , pp. 5-22
    • Reiter, R.J.1    Tan, D.X.2    Manchester, L.C.3
  • 191
    • 0031775322 scopus 로고    scopus 로고
    • Role of cyclooxygenase 2 in acute spinal cord injury
    • Resnick D.K., Graham S.H., Dixon C.E., et al. Role of cyclooxygenase 2 in acute spinal cord injury. J Neurotrauma 1998, 15:1005-1013.
    • (1998) J Neurotrauma , vol.15 , pp. 1005-1013
    • Resnick, D.K.1    Graham, S.H.2    Dixon, C.E.3
  • 192
    • 41249090606 scopus 로고    scopus 로고
    • Effect of 17beta-estradiol on functional outcome, release of cytokines, astrocyte reactivity and inflammatory spreading after spinal cord injury in male rats
    • Ritz M.F., Hausmann O.N. Effect of 17beta-estradiol on functional outcome, release of cytokines, astrocyte reactivity and inflammatory spreading after spinal cord injury in male rats. Brain Res 2008, 1203:177-188.
    • (2008) Brain Res , vol.1203 , pp. 177-188
    • Ritz, M.F.1    Hausmann, O.N.2
  • 193
    • 41849108753 scopus 로고    scopus 로고
    • Greatly improved neurological outcome after spinal cord compression injury in AQP4-deficient mice
    • Saadoun S., Bell B.A., Verkman A.S., et al. Greatly improved neurological outcome after spinal cord compression injury in AQP4-deficient mice. Brain 2008, 131:1087-1098.
    • (2008) Brain , vol.131 , pp. 1087-1098
    • Saadoun, S.1    Bell, B.A.2    Verkman, A.S.3
  • 194
    • 0023821194 scopus 로고
    • Exogenous GM1 gangliosides protect against retrograde degeneration following posterior neocortex lesions in developing hamsters
    • Sabel B.A., Gottlieb J., Schneider G.E. Exogenous GM1 gangliosides protect against retrograde degeneration following posterior neocortex lesions in developing hamsters. Brain Res 1988, 459:373-380.
    • (1988) Brain Res , vol.459 , pp. 373-380
    • Sabel, B.A.1    Gottlieb, J.2    Schneider, G.E.3
  • 195
    • 40849126421 scopus 로고    scopus 로고
    • Limited minocycline neuroprotection after balloon-compression spinal cord injury in the rat
    • Saganova K., Orendacova J., Cizkova D., et al. Limited minocycline neuroprotection after balloon-compression spinal cord injury in the rat. Neurosci Lett 2008, 433:246-249.
    • (2008) Neurosci Lett , vol.433 , pp. 246-249
    • Saganova, K.1    Orendacova, J.2    Cizkova, D.3
  • 196
    • 0032567689 scopus 로고    scopus 로고
    • Spontaneous long-term remyelination after traumatic spinal cord injury in rats
    • Salgado-Ceballos H., Guizar-Sahagun G., Feria-Velasco A., et al. Spontaneous long-term remyelination after traumatic spinal cord injury in rats. Brain Res 1998, 782:126-135.
    • (1998) Brain Res , vol.782 , pp. 126-135
    • Salgado-Ceballos, H.1    Guizar-Sahagun, G.2    Feria-Velasco, A.3
  • 197
    • 38149092274 scopus 로고    scopus 로고
    • Melatonin attenuates calpain upregulation, axonal damage and neuronal death in spinal cord injury in rats
    • Samantaray S., Sribnick E.A., Das A., et al. Melatonin attenuates calpain upregulation, axonal damage and neuronal death in spinal cord injury in rats. J Pineal Res 2008, 44:348-357.
    • (2008) J Pineal Res , vol.44 , pp. 348-357
    • Samantaray, S.1    Sribnick, E.A.2    Das, A.3
  • 198
    • 0025021931 scopus 로고
    • The role(s) of gangliosides in neural differentiation and repair: a perspective
    • Schengrund C.L. The role(s) of gangliosides in neural differentiation and repair: a perspective. Brain Res Bull 1990, 24:131-141.
    • (1990) Brain Res Bull , vol.24 , pp. 131-141
    • Schengrund, C.L.1
  • 199
    • 0034066304 scopus 로고    scopus 로고
    • Pretreatment with calpain inhibitor CEP-4143 inhibits calpain I activation and cytoskeletal degradation, improves neurological function, and enhances axonal survival after traumatic spinal cord injury
    • Schumacher P.A., Siman R.G., Fehlings M.G. Pretreatment with calpain inhibitor CEP-4143 inhibits calpain I activation and cytoskeletal degradation, improves neurological function, and enhances axonal survival after traumatic spinal cord injury. J Neurochem 2000, 74:1646-1655.
    • (2000) J Neurochem , vol.74 , pp. 1646-1655
    • Schumacher, P.A.1    Siman, R.G.2    Fehlings, M.G.3
  • 200
    • 34548610385 scopus 로고    scopus 로고
    • Progesterone: therapeutic opportunities for neuroprotection and myelin repair
    • Schumacher M., Guennoun R., Stein D.G., et al. Progesterone: therapeutic opportunities for neuroprotection and myelin repair. Pharmacol Ther 2007, 116:77-106.
    • (2007) Pharmacol Ther , vol.116 , pp. 77-106
    • Schumacher, M.1    Guennoun, R.2    Stein, D.G.3
  • 201
    • 0034867539 scopus 로고    scopus 로고
    • Evaluation of the neuroprotective effects of sodium channel blockers after spinal cord injury: improved behavioral and neuroanatomical recovery with riluzole
    • Schwartz G., Fehlings M.G. Evaluation of the neuroprotective effects of sodium channel blockers after spinal cord injury: improved behavioral and neuroanatomical recovery with riluzole. J Neurosurg 2001, 94:245-256.
    • (2001) J Neurosurg , vol.94 , pp. 245-256
    • Schwartz, G.1    Fehlings, M.G.2
  • 202
    • 0018372080 scopus 로고
    • Loss of autoregulation and posttraumatic ischemia following experimental spinal cord trauma
    • Senter H.J., Venes J.L. Loss of autoregulation and posttraumatic ischemia following experimental spinal cord trauma. J Neurosurg 1979, 50:198-206.
    • (1979) J Neurosurg , vol.50 , pp. 198-206
    • Senter, H.J.1    Venes, J.L.2
  • 203
    • 12344253802 scopus 로고    scopus 로고
    • Resolvins, docosatrienes, and neuroprotectins, novel omega-3-derived mediators, and their endogenous aspirin-triggered epimers
    • Serhan C.N., Arita M., Hong S., et al. Resolvins, docosatrienes, and neuroprotectins, novel omega-3-derived mediators, and their endogenous aspirin-triggered epimers. Lipids 2004, 39:1125-1132.
    • (2004) Lipids , vol.39 , pp. 1125-1132
    • Serhan, C.N.1    Arita, M.2    Hong, S.3
  • 204
    • 85052608491 scopus 로고    scopus 로고
    • Topical application of dynorphin A (1-17) antibodies attenuates neuronal nitric oxide synthase up-regulation, edema formation, and cell injury following focal trauma to the rat spinal cord
    • Sharma H.S., Nyberg F., Gordh T., et al. Topical application of dynorphin A (1-17) antibodies attenuates neuronal nitric oxide synthase up-regulation, edema formation, and cell injury following focal trauma to the rat spinal cord. Acta Neurochir Suppl 2006, 96:309-315.
    • (2006) Acta Neurochir Suppl , vol.96 , pp. 309-315
    • Sharma, H.S.1    Nyberg, F.2    Gordh, T.3
  • 205
    • 33645058421 scopus 로고    scopus 로고
    • Neuroprotective effects of melanocortins in experimental spinal cord injury. An experimental study in the rat using topical application of compounds with varying affinity to melanocortin receptors
    • Sharma H.S., Skottner A., Lundstedt T., et al. Neuroprotective effects of melanocortins in experimental spinal cord injury. An experimental study in the rat using topical application of compounds with varying affinity to melanocortin receptors. J Neural Transm 2006, 113:463-476.
    • (2006) J Neural Transm , vol.113 , pp. 463-476
    • Sharma, H.S.1    Skottner, A.2    Lundstedt, T.3
  • 206
    • 34247636111 scopus 로고    scopus 로고
    • Cyclosporin A has a protective effect with induced upregulation of Hsp70 and nNOS on severe spinal cord ischemic injury in rabbits
    • Shin Y.C., Choi K.Y., Kim W.G. Cyclosporin A has a protective effect with induced upregulation of Hsp70 and nNOS on severe spinal cord ischemic injury in rabbits. J Invest Surg 2007, 20:113-120.
    • (2007) J Invest Surg , vol.20 , pp. 113-120
    • Shin, Y.C.1    Choi, K.Y.2    Kim, W.G.3
  • 207
    • 33845628191 scopus 로고    scopus 로고
    • Riluzole promotes cell survival and neurite outgrowth in rat sensory neurones in vitro
    • Shortland P.J., Leinster V.H., White W., et al. Riluzole promotes cell survival and neurite outgrowth in rat sensory neurones in vitro. Eur J Neurosci 2006, 24:3343-3353.
    • (2006) Eur J Neurosci , vol.24 , pp. 3343-3353
    • Shortland, P.J.1    Leinster, V.H.2    White, W.3
  • 208
    • 47849092592 scopus 로고    scopus 로고
    • Estrogen actions on mitochondria - physiological and pathological implications
    • Simpkins J.W., Yang S.H., Sarkar S.N., et al. Estrogen actions on mitochondria - physiological and pathological implications. Mol Cell Endocrinol 2008, 290:51-59.
    • (2008) Mol Cell Endocrinol , vol.290 , pp. 51-59
    • Simpkins, J.W.1    Yang, S.H.2    Sarkar, S.N.3
  • 209
    • 0026351976 scopus 로고
    • The influence of long-term nifedipine or indomethacin therapy on neurologic recovery from experimental spinal cord injury
    • Simpson R.K., Baskin D.S., Dudley A.W., et al. The influence of long-term nifedipine or indomethacin therapy on neurologic recovery from experimental spinal cord injury. J Spinal Disord 1991, 4:420-427.
    • (1991) J Spinal Disord , vol.4 , pp. 420-427
    • Simpson, R.K.1    Baskin, D.S.2    Dudley, A.W.3
  • 210
    • 27844597182 scopus 로고    scopus 로고
    • Estrogen attenuated markers of inflammation and decreased lesion volume in acute spinal cord injury in rats
    • Sribnick E.A., Wingrave J.M., Matzelle D.D., et al. Estrogen attenuated markers of inflammation and decreased lesion volume in acute spinal cord injury in rats. J Neurosci Res 2005, 82:283-293.
    • (2005) J Neurosci Res , vol.82 , pp. 283-293
    • Sribnick, E.A.1    Wingrave, J.M.2    Matzelle, D.D.3
  • 211
    • 33749455023 scopus 로고    scopus 로고
    • Estrogen treatment of spinal cord injury attenuates calpain activation and apoptosis
    • Sribnick E.A., Matzelle D.D., Ray S.K., et al. Estrogen treatment of spinal cord injury attenuates calpain activation and apoptosis. J Neurosci Res 2006, 84:1064-1075.
    • (2006) J Neurosci Res , vol.84 , pp. 1064-1075
    • Sribnick, E.A.1    Matzelle, D.D.2    Ray, S.K.3
  • 212
    • 0037665153 scopus 로고    scopus 로고
    • Rats and mice exhibit distinct inflammatory reactions after spinal cord injury
    • Sroga J.M., Jones T.B., Kigerl K.A., et al. Rats and mice exhibit distinct inflammatory reactions after spinal cord injury. J Comp Neurol 2003, 462:223-240.
    • (2003) J Comp Neurol , vol.462 , pp. 223-240
    • Sroga, J.M.1    Jones, T.B.2    Kigerl, K.A.3
  • 213
    • 38349052883 scopus 로고    scopus 로고
    • Does progesterone have neuroprotective properties?
    • Stein D.G., Wright D.W., Kellermann A.L. Does progesterone have neuroprotective properties?. Ann Emerg Med 2008, 51:164-172.
    • (2008) Ann Emerg Med , vol.51 , pp. 164-172
    • Stein, D.G.1    Wright, D.W.2    Kellermann, A.L.3
  • 214
    • 1542376941 scopus 로고    scopus 로고
    • Minocycline treatment reduces delayed oligodendrocyte death, attenuates axonal dieback, and improves functional outcome after spinal cord injury
    • Stirling D.P., Khodarahmi K., Liu J., et al. Minocycline treatment reduces delayed oligodendrocyte death, attenuates axonal dieback, and improves functional outcome after spinal cord injury. J Neurosci 2004, 24:2182-2190.
    • (2004) J Neurosci , vol.24 , pp. 2182-2190
    • Stirling, D.P.1    Khodarahmi, K.2    Liu, J.3
  • 216
    • 58849083367 scopus 로고    scopus 로고
    • Depletion of Ly6G/Gr-1 leukocytes after spinal cord injury in mice alters wound healing and worsens neurological outcome
    • Stirling D.P., Liu S., Kubes P., et al. Depletion of Ly6G/Gr-1 leukocytes after spinal cord injury in mice alters wound healing and worsens neurological outcome. J Neurosci 2009, 29:753-764.
    • (2009) J Neurosci , vol.29 , pp. 753-764
    • Stirling, D.P.1    Liu, S.2    Kubes, P.3
  • 217
    • 0031815256 scopus 로고    scopus 로고
    • Cytokine mRNA profiles in contused spinal cord and axotomized facial nucleus suggest a beneficial role for inflammation and gliosis
    • Streit W.J., SempleRowland S.L., Hurley S.D., et al. Cytokine mRNA profiles in contused spinal cord and axotomized facial nucleus suggest a beneficial role for inflammation and gliosis. Exp Neurol 1998, 152:74-87.
    • (1998) Exp Neurol , vol.152 , pp. 74-87
    • Streit, W.J.1    SempleRowland, S.L.2    Hurley, S.D.3
  • 219
    • 34247166204 scopus 로고    scopus 로고
    • Gender differences in spinal cord injury are not estrogen-dependent
    • Swartz K.R., Fee D.B., Joy K.M., et al. Gender differences in spinal cord injury are not estrogen-dependent. J Neurotrauma 2007, 24:473-480.
    • (2007) J Neurotrauma , vol.24 , pp. 473-480
    • Swartz, K.R.1    Fee, D.B.2    Joy, K.M.3
  • 220
    • 0030845563 scopus 로고    scopus 로고
    • Role of neutrophils in spinal cord injury in the rat
    • Taoka Y., Okajima K., Uchiba M., et al. Role of neutrophils in spinal cord injury in the rat. Neurosci 1997, 79:1177-1182.
    • (1997) Neurosci , vol.79 , pp. 1177-1182
    • Taoka, Y.1    Okajima, K.2    Uchiba, M.3
  • 221
    • 0033825692 scopus 로고    scopus 로고
    • The effects of melatonin on the antioxidant systems in experimental spinal injury
    • Taskiran D., Tanyalcin T., Sozmen E.Y., et al. The effects of melatonin on the antioxidant systems in experimental spinal injury. Int J Neurosci 2000, 104:63-73.
    • (2000) Int J Neurosci , vol.104 , pp. 63-73
    • Taskiran, D.1    Tanyalcin, T.2    Sozmen, E.Y.3
  • 222
    • 0028812680 scopus 로고
    • Update on the pathophysiology and pathology of acute spinal cord injury
    • Tator C.H. Update on the pathophysiology and pathology of acute spinal cord injury. Brain Pathol 1995, 5:407-413.
    • (1995) Brain Pathol , vol.5 , pp. 407-413
    • Tator, C.H.1
  • 223
    • 0031017950 scopus 로고    scopus 로고
    • Vascular mechanisms in the pathophysiology of human spinal cord injury
    • Tator C.H., Koyanagi I. Vascular mechanisms in the pathophysiology of human spinal cord injury. J Neurosurg 1997, 86:483-492.
    • (1997) J Neurosurg , vol.86 , pp. 483-492
    • Tator, C.H.1    Koyanagi, I.2
  • 224
    • 12144290904 scopus 로고    scopus 로고
    • Minocycline inhibits contusion-triggered mitochondrial cytochrome c release and mitigates functional deficits after spinal cord injury
    • Teng Y.D., Choi H., Onario R.C., et al. Minocycline inhibits contusion-triggered mitochondrial cytochrome c release and mitigates functional deficits after spinal cord injury. Proc Natl Acad Sci U S A 2004, 101:3071-3076.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 3071-3076
    • Teng, Y.D.1    Choi, H.2    Onario, R.C.3
  • 225
    • 0033570133 scopus 로고    scopus 로고
    • Progesterone is neuroprotective after acute experimental spinal cord trauma in rats
    • Thomas A.J., Nockels R.P., Pan H.Q., et al. Progesterone is neuroprotective after acute experimental spinal cord trauma in rats. Spine 1999, 24:2134-2138.
    • (1999) Spine , vol.24 , pp. 2134-2138
    • Thomas, A.J.1    Nockels, R.P.2    Pan, H.Q.3
  • 226
    • 0033816426 scopus 로고    scopus 로고
    • Tirilazad mesylate in acute ischemic stroke: a systematic review
    • Tirilazad International Steering Committee
    • Tirilazad International Steering Committee Tirilazad mesylate in acute ischemic stroke: a systematic review. Stroke 2000, 31:2257-2265.
    • (2000) Stroke , vol.31 , pp. 2257-2265
  • 227
    • 0042074511 scopus 로고    scopus 로고
    • Effects of prostaglandin E1, melatonin, and oxytetracycline on lipid peroxidation, antioxidant defense system, paraoxonase (PON1) activities, and homocysteine levels in an animal model of spinal cord injury
    • Topsakal C., Kilic N., Ozveren F., et al. Effects of prostaglandin E1, melatonin, and oxytetracycline on lipid peroxidation, antioxidant defense system, paraoxonase (PON1) activities, and homocysteine levels in an animal model of spinal cord injury. Spine 2003, 28:1643-1652.
    • (2003) Spine , vol.28 , pp. 1643-1652
    • Topsakal, C.1    Kilic, N.2    Ozveren, F.3
  • 228
    • 18044391661 scopus 로고    scopus 로고
    • Spinal cord injury is accompanied by chronic progressive demyelination
    • Totoiu M.O., Keirstead H.S. Spinal cord injury is accompanied by chronic progressive demyelination. J Comp Neurol 2005, 486:373-383.
    • (2005) J Comp Neurol , vol.486 , pp. 373-383
    • Totoiu, M.O.1    Keirstead, H.S.2
  • 229
    • 33947204503 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-gamma agonists induce neuroprotection following transient focal ischemia in normotensive, normoglycemic as well as hypertensive and type-2 diabetic rodents
    • Tureyen K., Kapadia R., Bowen K.K., et al. Peroxisome proliferator-activated receptor-gamma agonists induce neuroprotection following transient focal ischemia in normotensive, normoglycemic as well as hypertensive and type-2 diabetic rodents. J Neurochem 2007, 101:41-56.
    • (2007) J Neurochem , vol.101 , pp. 41-56
    • Tureyen, K.1    Kapadia, R.2    Bowen, K.K.3
  • 230
    • 33845778397 scopus 로고    scopus 로고
    • Erythropoietin-mediated preservation of the white matter in rat spinal cord injury
    • Vitellaro-Zuccarello L., Mazzetti S., Madaschi L., et al. Erythropoietin-mediated preservation of the white matter in rat spinal cord injury. Neurosci 2007, 144:865-877.
    • (2007) Neurosci , vol.144 , pp. 865-877
    • Vitellaro-Zuccarello, L.1    Mazzetti, S.2    Madaschi, L.3
  • 231
    • 37849032039 scopus 로고    scopus 로고
    • Chronic erythropoietin-mediated effects on the expression of astrocyte markers in a rat model of contusive spinal cord injury
    • Vitellaro-Zuccarello L., Mazzetti S., Madaschi L., et al. Chronic erythropoietin-mediated effects on the expression of astrocyte markers in a rat model of contusive spinal cord injury. Neurosci 2008, 151:452-466.
    • (2008) Neurosci , vol.151 , pp. 452-466
    • Vitellaro-Zuccarello, L.1    Mazzetti, S.2    Madaschi, L.3
  • 232
    • 27444436746 scopus 로고    scopus 로고
    • Neuroimmunophilin ligands improve functional recovery and increase axonal growth after spinal cord hemisection in rats
    • Voda J., Yamaji T., Gold B.G. Neuroimmunophilin ligands improve functional recovery and increase axonal growth after spinal cord hemisection in rats. J Neurotrauma 2005, 22:1150-1161.
    • (2005) J Neurotrauma , vol.22 , pp. 1150-1161
    • Voda, J.1    Yamaji, T.2    Gold, B.G.3
  • 233
    • 34247598844 scopus 로고    scopus 로고
    • FK506 reduces the severity of cutaneous hypersensitivity in rats with a spinal cord contusion
    • Voda J., Hama A., Sagen J. FK506 reduces the severity of cutaneous hypersensitivity in rats with a spinal cord contusion. Neurosci Res 2007, 58:95-99.
    • (2007) Neurosci Res , vol.58 , pp. 95-99
    • Voda, J.1    Hama, A.2    Sagen, J.3
  • 234
    • 0032901935 scopus 로고    scopus 로고
    • GM1 ganglioside administration protects spinal neurons after glutamate excitotoxicity
    • Vorwerk C.K., Bonheur J., Kreutz M.R., et al. GM1 ganglioside administration protects spinal neurons after glutamate excitotoxicity. Restor Neurol Neurosci 1999, 14:47-51.
    • (1999) Restor Neurol Neurosci , vol.14 , pp. 47-51
    • Vorwerk, C.K.1    Bonheur, J.2    Kreutz, M.R.3
  • 235
    • 0029861617 scopus 로고    scopus 로고
    • Polyunsaturated fatty acids modulate sodium and calcium currents in CA1 neurons
    • Vreugdenhil M., Bruehl C., Voskuyl R.A., et al. Polyunsaturated fatty acids modulate sodium and calcium currents in CA1 neurons. Proc Natl Acad Sci U S A 1996, 93:12559-12563.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 12559-12563
    • Vreugdenhil, M.1    Bruehl, C.2    Voskuyl, R.A.3
  • 236
    • 0032605315 scopus 로고    scopus 로고
    • Neuroprotective effects of riluzole in neurotrauma models: a review
    • Wahl F., Stutzmann J.M. Neuroprotective effects of riluzole in neurotrauma models: a review. Acta Neurochir Suppl (Wien) 1999, 73:103-110.
    • (1999) Acta Neurochir Suppl (Wien) , vol.73 , pp. 103-110
    • Wahl, F.1    Stutzmann, J.M.2
  • 237
    • 0027428639 scopus 로고
    • GM-1 ganglioside administration combined with physical therapy restores ambulation in humans with chronic spinal cord injury
    • Walker J.B., Harris M. GM-1 ganglioside administration combined with physical therapy restores ambulation in humans with chronic spinal cord injury. Neurosci Lett 1993, 161:174-178.
    • (1993) Neurosci Lett , vol.161 , pp. 174-178
    • Walker, J.B.1    Harris, M.2
  • 238
    • 85026146954 scopus 로고    scopus 로고
    • Neuroprotective effect of docosahexaenoic acid on glutamate-induced cytotoxicity in rat hippocampal cultures
    • Wang X., Zhao X., Mao Z.Y., et al. Neuroprotective effect of docosahexaenoic acid on glutamate-induced cytotoxicity in rat hippocampal cultures. NeuroReport 2003, 14:2457-2461.
    • (2003) NeuroReport , vol.14 , pp. 2457-2461
    • Wang, X.1    Zhao, X.2    Mao, Z.Y.3
  • 239
    • 59849103451 scopus 로고    scopus 로고
    • Ibuprofen enhances recovery from spinal cord injury by limiting tissue loss and stimulating axonal growth
    • Wang X., Budel S., Baughman K., et al. Ibuprofen enhances recovery from spinal cord injury by limiting tissue loss and stimulating axonal growth. J Neurotrauma 2009, 26:81-95.
    • (2009) J Neurotrauma , vol.26 , pp. 81-95
    • Wang, X.1    Budel, S.2    Baughman, K.3
  • 240
    • 33745333417 scopus 로고    scopus 로고
    • Estrogen reduces the severity of autonomic dysfunction in spinal cord-injured male mice
    • Webb A.A., Chan C.B., Brown A., et al. Estrogen reduces the severity of autonomic dysfunction in spinal cord-injured male mice. Behav Brain Res 2006, 171:338-349.
    • (2006) Behav Brain Res , vol.171 , pp. 338-349
    • Webb, A.A.1    Chan, C.B.2    Brown, A.3
  • 241
    • 0037481943 scopus 로고    scopus 로고
    • Neuroprotection by minocycline facilitates significant recovery from spinal cord injury in mice
    • Wells J.E., Hurlbert R.J., Fehlings M.G., et al. Neuroprotection by minocycline facilitates significant recovery from spinal cord injury in mice. Brain 2003, 126:1628-1637.
    • (2003) Brain , vol.126 , pp. 1628-1637
    • Wells, J.E.1    Hurlbert, R.J.2    Fehlings, M.G.3
  • 242
    • 0028188555 scopus 로고
    • Naloxone reduces alterations in evoked potentials and edema in trauma to the rat spinal cord
    • Winkler T., Sharma H.S., Stalberg E., et al. Naloxone reduces alterations in evoked potentials and edema in trauma to the rat spinal cord. Acta Neurochir Suppl (Wien) 1994, 60:511-515.
    • (1994) Acta Neurochir Suppl (Wien) , vol.60 , pp. 511-515
    • Winkler, T.1    Sharma, H.S.2    Stalberg, E.3
  • 243
    • 33645760177 scopus 로고    scopus 로고
    • Decoy peptides that bind dynorphin noncovalently prevent NMDA receptor-mediated neurotoxicity
    • Woods A.S., Kaminski R., Oz M., et al. Decoy peptides that bind dynorphin noncovalently prevent NMDA receptor-mediated neurotoxicity. J Proteome Res 2006, 5:1017-1023.
    • (2006) J Proteome Res , vol.5 , pp. 1017-1023
    • Woods, A.S.1    Kaminski, R.2    Oz, M.3
  • 244
    • 0030054133 scopus 로고    scopus 로고
    • Amelioration of functional deficits from spinal cord trauma with systemically administered NBQX, an antagonist of non-N-methyl-d-aspartate receptors
    • Wrathall J.R., Teng Y.D., Choiniere D. Amelioration of functional deficits from spinal cord trauma with systemically administered NBQX, an antagonist of non-N-methyl-d-aspartate receptors. Exp Neurol 1996, 137:119-126.
    • (1996) Exp Neurol , vol.137 , pp. 119-126
    • Wrathall, J.R.1    Teng, Y.D.2    Choiniere, D.3
  • 245
    • 7244240590 scopus 로고    scopus 로고
    • Dietary omega-3 fatty acids normalize BDNF levels, reduce oxidative damage, and counteract learning disability after traumatic brain injury in rats
    • Wu A., Ying Z., Gomez-Pinilla F. Dietary omega-3 fatty acids normalize BDNF levels, reduce oxidative damage, and counteract learning disability after traumatic brain injury in rats. J Neurotrauma 2004, 21:1457-1467.
    • (2004) J Neurotrauma , vol.21 , pp. 1457-1467
    • Wu, A.1    Ying, Z.2    Gomez-Pinilla, F.3
  • 246
    • 26444572335 scopus 로고    scopus 로고
    • Erythropoietin is neuroprotective, improves functional recovery, and reduces neuronal apoptosis and inflammation in a rodent model of experimental closed head injury
    • Yatsiv I., Grigoriadis N., Simeonidou C., et al. Erythropoietin is neuroprotective, improves functional recovery, and reduces neuronal apoptosis and inflammation in a rodent model of experimental closed head injury. FASEB J 2005, 19:1701-1703.
    • (2005) FASEB J , vol.19 , pp. 1701-1703
    • Yatsiv, I.1    Grigoriadis, N.2    Simeonidou, C.3
  • 247
    • 56049113451 scopus 로고    scopus 로고
    • PPARgamma agonist rosiglitazone is neuroprotective after traumatic brain injury via anti-inflammatory and anti-oxidative mechanisms
    • Yi J.H., Park S.W., Brooks N., et al. PPARgamma agonist rosiglitazone is neuroprotective after traumatic brain injury via anti-inflammatory and anti-oxidative mechanisms. Brain Res 2008, 1244:164-172.
    • (2008) Brain Res , vol.1244 , pp. 164-172
    • Yi, J.H.1    Park, S.W.2    Brooks, N.3
  • 248
    • 35848955446 scopus 로고    scopus 로고
    • Sustained calpain inhibition improves locomotor function and tissue sparing following contusive spinal cord injury
    • Yu C.G., Geddes J.W. Sustained calpain inhibition improves locomotor function and tissue sparing following contusive spinal cord injury. Neurochem Res 2007, 32:2046-2053.
    • (2007) Neurochem Res , vol.32 , pp. 2046-2053
    • Yu, C.G.1    Geddes, J.W.2
  • 249
    • 0001832037 scopus 로고    scopus 로고
    • Beneficial effects of modest systemic hypothermia on locomotor function and histopathological damage following contusion-induced spinal cord injury in rats
    • Yu C.G., Jimenez O., Marcillo A.E., et al. Beneficial effects of modest systemic hypothermia on locomotor function and histopathological damage following contusion-induced spinal cord injury in rats. J Neurosurg 2000, 93:85-93.
    • (2000) J Neurosurg , vol.93 , pp. 85-93
    • Yu, C.G.1    Jimenez, O.2    Marcillo, A.E.3
  • 250
    • 0034971395 scopus 로고    scopus 로고
    • Detrimental effects of systemic hyperthermia on locomotor function and histopathological outcome after traumatic spinal cord injury in the rat
    • Yu C.G., Jagid J., Ruenes G., et al. Detrimental effects of systemic hyperthermia on locomotor function and histopathological outcome after traumatic spinal cord injury in the rat. Neurosurgery 2001, 49:152-158.
    • (2001) Neurosurgery , vol.49 , pp. 152-158
    • Yu, C.G.1    Jagid, J.2    Ruenes, G.3
  • 251
    • 48249117463 scopus 로고    scopus 로고
    • Intraspinal MDL28170 microinjection improves functional and pathological outcome following spinal cord injury
    • Yu C.G., Joshi A., Geddes J.W. Intraspinal MDL28170 microinjection improves functional and pathological outcome following spinal cord injury. J Neurotrauma 2008, 25:833-840.
    • (2008) J Neurotrauma , vol.25 , pp. 833-840
    • Yu, C.G.1    Joshi, A.2    Geddes, J.W.3
  • 252
    • 1642482615 scopus 로고    scopus 로고
    • Systemic administration of 17beta-estradiol reduces apoptotic cell death and improves functional recovery following traumatic spinal cord injury in rats
    • Yune T.Y., Kim S.J., Lee S.M., et al. Systemic administration of 17beta-estradiol reduces apoptotic cell death and improves functional recovery following traumatic spinal cord injury in rats. J Neurotrauma 2004, 21:293-306.
    • (2004) J Neurotrauma , vol.21 , pp. 293-306
    • Yune, T.Y.1    Kim, S.J.2    Lee, S.M.3
  • 253
    • 34447643571 scopus 로고    scopus 로고
    • Minocycline alleviates death of oligodendrocytes by inhibiting pro-nerve growth factor production in microglia after spinal cord injury
    • Yune T.Y., Lee J.Y., Jung G.Y., et al. Minocycline alleviates death of oligodendrocytes by inhibiting pro-nerve growth factor production in microglia after spinal cord injury. J Neurosci 2007, 27:7751-7761.
    • (2007) J Neurosci , vol.27 , pp. 7751-7761
    • Yune, T.Y.1    Lee, J.Y.2    Jung, G.Y.3
  • 254
    • 51849120763 scopus 로고    scopus 로고
    • Estrogen-induced Bcl-2 expression after spinal cord injury is mediated through phosphoinositide-3-kinase/Akt-dependent CREB activation
    • Yune T.Y., Park H.G., Lee J.Y., et al. Estrogen-induced Bcl-2 expression after spinal cord injury is mediated through phosphoinositide-3-kinase/Akt-dependent CREB activation. J Neurotrauma 2008, 25:1121-1131.
    • (2008) J Neurotrauma , vol.25 , pp. 1121-1131
    • Yune, T.Y.1    Park, H.G.2    Lee, J.Y.3
  • 255
    • 0344153775 scopus 로고    scopus 로고
    • Leukemia inhibitory factor promotes recovery of locomotor function following spinal cord injury in the mouse
    • Zang D.W., Cheema S.S. Leukemia inhibitory factor promotes recovery of locomotor function following spinal cord injury in the mouse. J Neurotrauma 2003, 20:1215-1222.
    • (2003) J Neurotrauma , vol.20 , pp. 1215-1222
    • Zang, D.W.1    Cheema, S.S.2
  • 256
    • 0242414463 scopus 로고    scopus 로고
    • Nonsteroidal anti-inflammatory drugs can lower amyloidogenic Abeta42 by inhibiting Rho
    • Zhou Y., Su Y., Li B., et al. Nonsteroidal anti-inflammatory drugs can lower amyloidogenic Abeta42 by inhibiting Rho. Science 2003, 302:1215-1217.
    • (2003) Science , vol.302 , pp. 1215-1217
    • Zhou, Y.1    Su, Y.2    Li, B.3


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