메뉴 건너뛰기




Volumn 12, Issue 1, 2005, Pages 17-27

Sex differences and the effect of hormonal therapy on ischemic brain injury

Author keywords

Estrogen; Hormones; Ischemia; Mechanisms of action; Progesterone

Indexed keywords

ESTRADIOL; ESTROGEN; PROGESTERONE; TESTOSTERONE;

EID: 20344394421     PISSN: 09284680     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pathophys.2005.02.009     Document Type: Review
Times cited : (28)

References (124)
  • 4
    • 7644232957 scopus 로고    scopus 로고
    • Hormone replacement therapy and stroke: Clinical trials review
    • L.M. Brass Hormone replacement therapy and stroke: clinical trials review Stroke 35 2004 2644 2647
    • (2004) Stroke , vol.35 , pp. 2644-2647
    • Brass, L.M.1
  • 5
    • 0038363692 scopus 로고    scopus 로고
    • Estrogens: Protective or risk factors in brain function?
    • P.M. Wise Estrogens: protective or risk factors in brain function? Prog. Neurobiol. 69 2003 181 191
    • (2003) Prog. Neurobiol. , vol.69 , pp. 181-191
    • Wise, P.M.1
  • 7
    • 0033976986 scopus 로고    scopus 로고
    • Neuroprotective effects of female gonadal steroids in reproductively senescent female rats
    • N.J. Alkayed, S.J. Murphy, R.J. Traystman, P.D. Hurn, and V.M. Miller Neuroprotective effects of female gonadal steroids in reproductively senescent female rats Stroke 31 2000 161 168
    • (2000) Stroke , vol.31 , pp. 161-168
    • Alkayed, N.J.1    Murphy, S.J.2    Traystman, R.J.3    Hurn, P.D.4    Miller, V.M.5
  • 9
    • 0032536475 scopus 로고    scopus 로고
    • Effects of gender and estradiol treatment on focal brain ischemia
    • Y.Q. Zhang, J. Shi, G. Rajakumar, A.L. Day, and J.W. Simpkins Effects of gender and estradiol treatment on focal brain ischemia Brain Res. 784 1998 321 324
    • (1998) Brain Res. , vol.784 , pp. 321-324
    • Zhang, Y.Q.1    Shi, J.2    Rajakumar, G.3    Day, A.L.4    Simpkins, J.W.5
  • 10
    • 0034018107 scopus 로고    scopus 로고
    • Estradiol exerts neuroprotective effects when administered after ischemic insult
    • S.H. Yang, J. Shi, A.L. Day, and J.W. Simpkins Estradiol exerts neuroprotective effects when administered after ischemic insult Stroke 31 2000 745 749 discussion, pp. 749-750
    • (2000) Stroke , vol.31 , pp. 745-749
    • Yang, S.H.1    Shi, J.2    Day, A.L.3    Simpkins, J.W.4
  • 12
    • 0032325413 scopus 로고    scopus 로고
    • The effects of 17beta-estradiol on ischemia-induced neuronal damage in the gerbil hippocampus
    • J. Chen, N. Adachi, K. Liu, and T. Arai The effects of 17beta-estradiol on ischemia-induced neuronal damage in the gerbil hippocampus Neuroscience 87 1998 817 822
    • (1998) Neuroscience , vol.87 , pp. 817-822
    • Chen, J.1    Adachi, N.2    Liu, K.3    Arai, T.4
  • 14
    • 0345714772 scopus 로고    scopus 로고
    • 17beta-Estradiol extends ischemic thresholds and exerts neuroprotective effects in cerebral subcortex against transient focal cerebral ischemia in rats
    • T. Fan, S.H. Yang, E. Johnson, B. Osteen, R. Hayes, A.L. Day, and J.W. Simpkins 17beta-Estradiol extends ischemic thresholds and exerts neuroprotective effects in cerebral subcortex against transient focal cerebral ischemia in rats Brain Res. 993 2003 10 17
    • (2003) Brain Res. , vol.993 , pp. 10-17
    • Fan, T.1    Yang, S.H.2    Johnson, E.3    Osteen, B.4    Hayes, R.5    Day, A.L.6    Simpkins, J.W.7
  • 15
    • 0033967462 scopus 로고    scopus 로고
    • Ovariectomy exacerbates and estrogen replacement attenuates photothrombotic focal ischemic brain injury in rats
    • K. Fukuda, H. Yao, S. Ibayashi, T. Nakahara, H. Uchimura, M. Fujishima, and E.D. Hall Ovariectomy exacerbates and estrogen replacement attenuates photothrombotic focal ischemic brain injury in rats Stroke 31 2000 155 160
    • (2000) Stroke , vol.31 , pp. 155-160
    • Fukuda, K.1    Yao, H.2    Ibayashi, S.3    Nakahara, T.4    Uchimura, H.5    Fujishima, M.6    Hall, E.D.7
  • 16
    • 0032527057 scopus 로고    scopus 로고
    • Testosterone increases and estradiol decreases middle cerebral artery occlusion lesion size in male rats
    • T. Hawk, Y.Q. Zhang, G. Rajakumar, A.L. Day, and J.W. Simpkins Testosterone increases and estradiol decreases middle cerebral artery occlusion lesion size in male rats Brain Res. 796 1998 296 298
    • (1998) Brain Res. , vol.796 , pp. 296-298
    • Hawk, T.1    Zhang, Y.Q.2    Rajakumar, G.3    Day, A.L.4    Simpkins, J.W.5
  • 17
    • 0037088929 scopus 로고    scopus 로고
    • Estrogen protects against global ischemia-induced neuronal death and prevents activation of apoptotic signaling cascades in the hippocampal CA1
    • T. Jover, H. Tanaka, A. Calderone, K. Oguro, M.V. Bennett, A.M. Etgen, and R.S. Zukin Estrogen protects against global ischemia-induced neuronal death and prevents activation of apoptotic signaling cascades in the hippocampal CA1 J. Neurosci. 22 2002 2115 2124
    • (2002) J. Neurosci. , vol.22 , pp. 2115-2124
    • Jover, T.1    Tanaka, H.2    Calderone, A.3    Oguro, K.4    Bennett, M.V.5    Etgen, A.M.6    Zukin, R.S.7
  • 18
    • 0034745252 scopus 로고    scopus 로고
    • Postischemic estrogen reduces hypoperfusion and secondary ischemia after experimental stroke
    • L.D. McCullough, N.J. Alkayed, R.J. Traystman, M.J. Williams, and P.D. Hurn Postischemic estrogen reduces hypoperfusion and secondary ischemia after experimental stroke Stroke 32 2001 796 802
    • (2001) Stroke , vol.32 , pp. 796-802
    • McCullough, L.D.1    Alkayed, N.J.2    Traystman, R.J.3    Williams, M.J.4    Hurn, P.D.5
  • 19
    • 0032487513 scopus 로고    scopus 로고
    • Cerebral vasodilating capacity during forebrain ischemia: Effects of chronic estrogen depletion and repletion and the role of neuronal nitric oxide synthase
    • D.A. Pelligrino, R. Santizo, V.L. Baughman, and Q. Wang Cerebral vasodilating capacity during forebrain ischemia: effects of chronic estrogen depletion and repletion and the role of neuronal nitric oxide synthase Neuroreport 9 1998 3285 3291
    • (1998) Neuroreport , vol.9 , pp. 3285-3291
    • Pelligrino, D.A.1    Santizo, R.2    Baughman, V.L.3    Wang, Q.4
  • 20
    • 5444274657 scopus 로고    scopus 로고
    • 17beta-estradiol pretreatment reduces CA1 sector cell death and the spontaneous hyperthermia that follows forebrain ischemia in the gerbil
    • W.C. Plahta, D.L. Clark, and F. Colbourne 17beta-estradiol pretreatment reduces CA1 sector cell death and the spontaneous hyperthermia that follows forebrain ischemia in the gerbil Neuroscience 129 2004 187 193
    • (2004) Neuroscience , vol.129 , pp. 187-193
    • Plahta, W.C.1    Clark, D.L.2    Colbourne, F.3
  • 22
    • 0037450414 scopus 로고    scopus 로고
    • Estrogen prevents the loss of CA1 hippocampal neurons in gerbils after ischemic injury
    • P.J. Shughrue, and I. Merchenthaler Estrogen prevents the loss of CA1 hippocampal neurons in gerbils after ischemic injury Neuroscience 116 2003 851 861
    • (2003) Neuroscience , vol.116 , pp. 851-861
    • Shughrue, P.J.1    Merchenthaler, I.2
  • 23
    • 0031904678 scopus 로고    scopus 로고
    • Estrogen-mediated neuroprotection after experimental stroke in male rats
    • T.J. Toung, R.J. Traystman, and P.D. Hurn Estrogen-mediated neuroprotection after experimental stroke in male rats Stroke 29 1998 1666 1670
    • (1998) Stroke , vol.29 , pp. 1666-1670
    • Toung, T.J.1    Traystman, R.J.2    Hurn, P.D.3
  • 25
    • 0032724682 scopus 로고    scopus 로고
    • Neuroprotective effects of progesterone after transient middle cerebral artery occlusion in rat
    • J. Chen, M. Chopp, and Y. Li Neuroprotective effects of progesterone after transient middle cerebral artery occlusion in rat J. Neurol. Sci. 171 1999 24 30
    • (1999) J. Neurol. Sci. , vol.171 , pp. 24-30
    • Chen, J.1    Chopp, M.2    Li, Y.3
  • 26
    • 3042773856 scopus 로고    scopus 로고
    • Progesterone enhances functional recovery after middle cerebral artery occlusion in male mice
    • C.L. Gibson, and S.P. Murphy Progesterone enhances functional recovery after middle cerebral artery occlusion in male mice J. Cereb. Blood Flow Metab. 24 2004 805 813
    • (2004) J. Cereb. Blood Flow Metab. , vol.24 , pp. 805-813
    • Gibson, C.L.1    Murphy, S.P.2
  • 27
    • 0030607198 scopus 로고    scopus 로고
    • Progesterone is neuroprotective after transient middle cerebral artery occlusion in male rats
    • N. Jiang, M. Chopp, D. Stein, and H. Feit Progesterone is neuroprotective after transient middle cerebral artery occlusion in male rats Brain Res. 735 1996 101 107
    • (1996) Brain Res. , vol.735 , pp. 101-107
    • Jiang, N.1    Chopp, M.2    Stein, D.3    Feit, H.4
  • 28
    • 0034016139 scopus 로고    scopus 로고
    • Neuroprotective effect of postischemic administration of progesterone in spontaneously hypertensive rats with focal cerebral ischemia
    • Y. Kumon, S.C. Kim, P. Tompkins, A. Stevens, S. Sakaki, and C.M. Loftus Neuroprotective effect of postischemic administration of progesterone in spontaneously hypertensive rats with focal cerebral ischemia J. Neurosurg. 92 2000 848 852
    • (2000) J. Neurosurg. , vol.92 , pp. 848-852
    • Kumon, Y.1    Kim, S.C.2    Tompkins, P.3    Stevens, A.4    Sakaki, S.5    Loftus, C.M.6
  • 29
    • 0036791875 scopus 로고    scopus 로고
    • Progesterone administration during reperfusion, but not preischemia alone, reduces injury in ovariectomized rats
    • S.J. Murphy, M.T. Littleton-Kearney, and P.D. Hurn Progesterone administration during reperfusion, but not preischemia alone, reduces injury in ovariectomized rats J. Cereb. Blood Flow Metab. 22 2002 1181 1188
    • (2002) J. Cereb. Blood Flow Metab. , vol.22 , pp. 1181-1188
    • Murphy, S.J.1    Littleton-Kearney, M.T.2    Hurn, P.D.3
  • 30
    • 4944246436 scopus 로고    scopus 로고
    • Effects of combined estrogen and progesterone on brain infarction in reproductively senescent female rats
    • T.J. Toung, T.-Y. Chen, M.T. Littleton-Kearney, P.D. Hurn, and S.J. Murphy Effects of combined estrogen and progesterone on brain infarction in reproductively senescent female rats J. Cereb. Blood Flow Metab. 24 2004 1160 1166
    • (2004) J. Cereb. Blood Flow Metab. , vol.24 , pp. 1160-1166
    • Toung, T.J.1    Chen, T.-Y.2    Littleton-Kearney, M.T.3    Hurn, P.D.4    Murphy, S.J.5
  • 32
    • 0035805173 scopus 로고    scopus 로고
    • Deleterious effect of beta-estradiol in a rat model of transient forebrain ischemia
    • I. Harukuni, P.D. Hurn, and B.J. Crain Deleterious effect of beta-estradiol in a rat model of transient forebrain ischemia Brain Res. 900 2001 137 142
    • (2001) Brain Res. , vol.900 , pp. 137-142
    • Harukuni, I.1    Hurn, P.D.2    Crain, B.J.3
  • 33
    • 0034102549 scopus 로고    scopus 로고
    • Progesterone exacerbates striatal stroke injury in progesterone-deficient female animals
    • S.J. Murphy, R.J. Traystman, P.D. Hurn, and S.P. Duckles Progesterone exacerbates striatal stroke injury in progesterone-deficient female animals Stroke 31 2000 1173 1178
    • (2000) Stroke , vol.31 , pp. 1173-1178
    • Murphy, S.J.1    Traystman, R.J.2    Hurn, P.D.3    Duckles, S.P.4
  • 36
    • 0033004253 scopus 로고    scopus 로고
    • Estrogen provides neuroprotection in transient forebrain ischemia through perfusion-independent mechanisms in rats
    • Q. Wang, R. Santizo, V.L. Baughman, D.A. Pelligrino, and C. Iadecola Estrogen provides neuroprotection in transient forebrain ischemia through perfusion-independent mechanisms in rats Stroke 30 1999 630 637
    • (1999) Stroke , vol.30 , pp. 630-637
    • Wang, Q.1    Santizo, R.2    Baughman, V.L.3    Pelligrino, D.A.4    Iadecola, C.5
  • 37
    • 0032501198 scopus 로고    scopus 로고
    • Estrogen attenuates over-expression of beta-amyloid precursor protein messager RNA in an animal model of focal ischemia
    • J. Shi, K.S. Panickar, S.H. Yang, O. Rabbani, A.L. Day, and J.W. Simpkins Estrogen attenuates over-expression of beta-amyloid precursor protein messager RNA in an animal model of focal ischemia Brain Res. 810 1998 87 92
    • (1998) Brain Res. , vol.810 , pp. 87-92
    • Shi, J.1    Panickar, K.S.2    Yang, S.H.3    Rabbani, O.4    Day, A.L.5    Simpkins, J.W.6
  • 39
    • 0033588352 scopus 로고    scopus 로고
    • Estradiol inhibits leukocyte adhesion and transendothelial migration in rabbits in vivo: Possible mechanisms for gender differences in atherosclerosis
    • L. Nathan, S. Pervin, R. Singh, M. Rosenfeld, and G. Chaudhuri Estradiol inhibits leukocyte adhesion and transendothelial migration in rabbits in vivo: possible mechanisms for gender differences in atherosclerosis Circ. Res. 85 1999 377 385
    • (1999) Circ. Res. , vol.85 , pp. 377-385
    • Nathan, L.1    Pervin, S.2    Singh, R.3    Rosenfeld, M.4    Chaudhuri, G.5
  • 40
    • 0033816278 scopus 로고    scopus 로고
    • Effects of estrogen on leukocyte adhesion after transient forebrain ischemia
    • R.A. Santizo, S. Anderson, S. Ye, H.M. Koenig, and D.A. Pelligrino Effects of estrogen on leukocyte adhesion after transient forebrain ischemia Stroke 31 2000 2231 2235
    • (2000) Stroke , vol.31 , pp. 2231-2235
    • Santizo, R.A.1    Anderson, S.2    Ye, S.3    Koenig, H.M.4    Pelligrino, D.A.5
  • 42
    • 0032813510 scopus 로고    scopus 로고
    • Oestrogen receptors - An overview
    • E. Enmark, and J.A. Gustafsson Oestrogen receptors - an overview J. Intern. Med. 246 1999 133 138
    • (1999) J. Intern. Med. , vol.246 , pp. 133-138
    • Enmark, E.1    Gustafsson, J.A.2
  • 43
    • 0029962414 scopus 로고    scopus 로고
    • The vascular protective effects of estrogen
    • M.Y. Farhat, M.C. Lavigne, and P.W. Ramwell The vascular protective effects of estrogen FASEB J. 10 1996 615 624
    • (1996) FASEB J. , vol.10 , pp. 615-624
    • Farhat, M.Y.1    Lavigne, M.C.2    Ramwell, P.W.3
  • 44
    • 0034681917 scopus 로고    scopus 로고
    • Estrogen receptors alpha and beta: Prevalence of estrogen receptor beta mRNA in human vascular smooth muscle and transcriptional effects
    • Y.K. Hodges, L. Tung, X.D. Yan, J.D. Graham, K.B. Horwitz, and L.D. Horwitz Estrogen receptors alpha and beta: prevalence of estrogen receptor beta mRNA in human vascular smooth muscle and transcriptional effects Circulation 101 2000 1792 1798
    • (2000) Circulation , vol.101 , pp. 1792-1798
    • Hodges, Y.K.1    Tung, L.2    Yan, X.D.3    Graham, J.D.4    Horwitz, K.B.5    Horwitz, L.D.6
  • 45
    • 0023879461 scopus 로고
    • Effect of 17 beta-estradiol on endothelium-dependent responses in the rabbit
    • V. Gisclard, V.M. Miller, and P.M. Vanhoutte Effect of 17 beta-estradiol on endothelium-dependent responses in the rabbit J. Pharmacol. Exp. Ther. 244 1988 19 22
    • (1988) J. Pharmacol. Exp. Ther. , vol.244 , pp. 19-22
    • Gisclard, V.1    Miller, V.M.2    Vanhoutte, P.M.3
  • 46
    • 0028854347 scopus 로고
    • Estrogen pretreatment directly potentiates endothelium-dependent vasorelaxation of porcine coronary arteries
    • D.R. Bell, H.J. Rensberger, D.R. Koritnik, and A. Koshy Estrogen pretreatment directly potentiates endothelium-dependent vasorelaxation of porcine coronary arteries Am. J. Physiol. 268 1995 377 383
    • (1995) Am. J. Physiol. , vol.268 , pp. 377-383
    • Bell, D.R.1    Rensberger, H.J.2    Koritnik, D.R.3    Koshy, A.4
  • 47
    • 0026437582 scopus 로고
    • Basal release of nitric oxide from aortic rings is greater in female rabbits than in male rabbits: Implications for atherosclerosis
    • T. Hayashi, J.M. Fukuto, L.J. Ignarro, and G. Chaudhuri Basal release of nitric oxide from aortic rings is greater in female rabbits than in male rabbits: implications for atherosclerosis Proc. Natl. Acad. Sci. U.S.A. 89 1992 11259 11263
    • (1992) Proc. Natl. Acad. Sci. U.S.A. , vol.89 , pp. 11259-11263
    • Hayashi, T.1    Fukuto, J.M.2    Ignarro, L.J.3    Chaudhuri, G.4
  • 48
    • 0028964018 scopus 로고
    • Up-regulation of nitric oxide synthase by estradiol in human aortic endothelial cells
    • K. Hishikawa, T. Nakaki, T. Marumo, H. Suzuki, R. Kato, and T. Saruta Up-regulation of nitric oxide synthase by estradiol in human aortic endothelial cells FEBS Lett. 360 1995 291 293
    • (1995) FEBS Lett. , vol.360 , pp. 291-293
    • Hishikawa, K.1    Nakaki, T.2    Marumo, T.3    Suzuki, H.4    Kato, R.5    Saruta, T.6
  • 49
    • 0030843573 scopus 로고    scopus 로고
    • Estrogen upregulates endothelial nitric oxide synthase gene expression in fetal pulmonary artery endothelium
    • A.N. MacRitchie, S.S. Jun, Z. Chen, Z. German, I.S. Yuhanna, T.S. Sherman, and P.W. Shaul Estrogen upregulates endothelial nitric oxide synthase gene expression in fetal pulmonary artery endothelium Circ. Res. 81 1997 355 362
    • (1997) Circ. Res. , vol.81 , pp. 355-362
    • MacRitchie, A.N.1    Jun, S.S.2    Chen, Z.3    German, Z.4    Yuhanna, I.S.5    Sherman, T.S.6    Shaul, P.W.7
  • 51
    • 0034607151 scopus 로고    scopus 로고
    • Nitric-oxide-dependent pial arteriolar dilation in the female rat: Effects of chronic estrogen depletion and repletion
    • D.A. Pelligrino, S. Ye, F. Tan, R.A. Santizo, D.L. Feinstein, and Q. Wang Nitric-oxide-dependent pial arteriolar dilation in the female rat: effects of chronic estrogen depletion and repletion Biochem. Biophys. Res. Commun. 269 2000 165 171
    • (2000) Biochem. Biophys. Res. Commun. , vol.269 , pp. 165-171
    • Pelligrino, D.A.1    Ye, S.2    Tan, F.3    Santizo, R.A.4    Feinstein, D.L.5    Wang, Q.6
  • 53
    • 7044231160 scopus 로고    scopus 로고
    • Selective estrogen receptor modulators protect hippocampal neurons from kainic acid excitotoxicity: Differences with the effect of estradiol
    • I. Ciriza, P. Carrero, I. Azcoitia, S.G. Lundeen, and L.M. Garcia-Segura Selective estrogen receptor modulators protect hippocampal neurons from kainic acid excitotoxicity: differences with the effect of estradiol J. Neurobiol. 61 2004 209 221
    • (2004) J. Neurobiol. , vol.61 , pp. 209-221
    • Ciriza, I.1    Carrero, P.2    Azcoitia, I.3    Lundeen, S.G.4    Garcia-Segura, L.M.5
  • 54
    • 0029924284 scopus 로고    scopus 로고
    • Estrogens attenuate and corticosterone exacerbates excitotoxicity, oxidative injury, and amyloid beta-peptide toxicity in hippocampal neurons
    • Y. Goodman, A.J. Bruce, B. Cheng, and M.P. Mattson Estrogens attenuate and corticosterone exacerbates excitotoxicity, oxidative injury, and amyloid beta-peptide toxicity in hippocampal neurons J. Neurochem. 66 1996 1836 1844
    • (1996) J. Neurochem. , vol.66 , pp. 1836-1844
    • Goodman, Y.1    Bruce, A.J.2    Cheng, B.3    Mattson, M.P.4
  • 55
    • 5444268694 scopus 로고    scopus 로고
    • Estradiol acutely attenuates glutamate-induced calcium overload in primarily cultured rat hippocampal neurons through a membrane receptor-dependent mechanism
    • Y. Huang, Y.L. Huang, S. Zhang, Y.C. Zhu, and T. Yao Estradiol acutely attenuates glutamate-induced calcium overload in primarily cultured rat hippocampal neurons through a membrane receptor-dependent mechanism Brain Res. 1026 2004 254 260
    • (2004) Brain Res. , vol.1026 , pp. 254-260
    • Huang, Y.1    Huang, Y.L.2    Zhang, S.3    Zhu, Y.C.4    Yao, T.5
  • 56
    • 0030848432 scopus 로고    scopus 로고
    • Estrogens attenuate neuronal injury due to hemoglobin, chemical hypoxia, and excitatory amino acids in murine cortical cultures
    • R.F. Regan, and Y. Guo Estrogens attenuate neuronal injury due to hemoglobin, chemical hypoxia, and excitatory amino acids in murine cortical cultures Brain Res. 764 1997 133 140
    • (1997) Brain Res. , vol.764 , pp. 133-140
    • Regan, R.F.1    Guo, Y.2
  • 57
    • 0030570392 scopus 로고    scopus 로고
    • Estrogen protects primary cortical neurons from glutamate toxicity
    • C.A. Singer, K.L. Rogers, T.M. Strickland, and D.M. Dorsa Estrogen protects primary cortical neurons from glutamate toxicity Neurosci. Lett. 212 1996 13 16
    • (1996) Neurosci. Lett. , vol.212 , pp. 13-16
    • Singer, C.A.1    Rogers, K.L.2    Strickland, T.M.3    Dorsa, D.M.4
  • 58
    • 0031552508 scopus 로고    scopus 로고
    • 17beta-Estradiol protects against NMDA-induced excitotoxicity by direct inhibition of NMDA receptors
    • C.E. Weaver Jr., M. Park-Chung, T.T. Gibbs, and D.H. Farb 17beta-Estradiol protects against NMDA-induced excitotoxicity by direct inhibition of NMDA receptors Brain Res. 761 1997 338 341
    • (1997) Brain Res. , vol.761 , pp. 338-341
    • Weaver Jr., C.E.1    Park-Chung, M.2    Gibbs, T.T.3    Farb, D.H.4
  • 59
    • 0027249424 scopus 로고
    • Steroid hormones protect spinal cord neurons from glutamate toxicity
    • T. Ogata, Y. Nakamura, K. Tsuji, T. Shibata, and K. Kataoka Steroid hormones protect spinal cord neurons from glutamate toxicity Neuroscience 55 1993 445 449
    • (1993) Neuroscience , vol.55 , pp. 445-449
    • Ogata, T.1    Nakamura, Y.2    Tsuji, K.3    Shibata, T.4    Kataoka, K.5
  • 60
    • 0025905651 scopus 로고
    • Progesterone administration attenuates excitatory amino acid responses of cerebellar Purkinje cells
    • S.S. Smith Progesterone administration attenuates excitatory amino acid responses of cerebellar Purkinje cells Neuroscience 42 1991 309 320
    • (1991) Neuroscience , vol.42 , pp. 309-320
    • Smith, S.S.1
  • 61
    • 0023271933 scopus 로고
    • Progesterone alters GABA and glutamate responsiveness: A possible mechanism for its anxiolytic action
    • S.S. Smith, B.D. Waterhouse, J.K. Chapin, and D.J. Woodward Progesterone alters GABA and glutamate responsiveness: a possible mechanism for its anxiolytic action Brain Res. 400 1987 353 359
    • (1987) Brain Res. , vol.400 , pp. 353-359
    • Smith, S.S.1    Waterhouse, B.D.2    Chapin, J.K.3    Woodward, D.J.4
  • 62
    • 0024381563 scopus 로고
    • Regulation of high-affinity GABAA receptors in the dorsal hippocampus by estradiol and progesterone
    • M. Schumacher, H. Coirini, and B.S. McEwen Regulation of high-affinity GABAA receptors in the dorsal hippocampus by estradiol and progesterone Brain Res. 487 1989 178 183
    • (1989) Brain Res. , vol.487 , pp. 178-183
    • Schumacher, M.1    Coirini, H.2    McEwen, B.S.3
  • 63
    • 0026471940 scopus 로고
    • Glutamic acid decarboxylase messenger ribonucleic acid is regulated by estradiol and progesterone in the hippocampus
    • N.G. Weiland Glutamic acid decarboxylase messenger ribonucleic acid is regulated by estradiol and progesterone in the hippocampus Endocrinology 131 1992 2697 2702
    • (1992) Endocrinology , vol.131 , pp. 2697-2702
    • Weiland, N.G.1
  • 64
    • 0029127278 scopus 로고
    • Specific subunit mRNAs of the GABAA receptor are regulated by progesterone in subfields of the hippocampus
    • N.G. Weiland, and M. Orchinik Specific subunit mRNAs of the GABAA receptor are regulated by progesterone in subfields of the hippocampus Brain Res. Mol. Brain Res. 32 1995 271 278
    • (1995) Brain Res. Mol. Brain Res. , vol.32 , pp. 271-278
    • Weiland, N.G.1    Orchinik, M.2
  • 65
    • 3242669822 scopus 로고    scopus 로고
    • Estrogen attenuates neuronal excitability in the insular cortex following middle cerebral artery occlusion
    • T.M. Saleh, B.J. Connell, C. Legge, and A.E. Cribb Estrogen attenuates neuronal excitability in the insular cortex following middle cerebral artery occlusion Brain Res. 1018 2004 119 129
    • (2004) Brain Res. , vol.1018 , pp. 119-129
    • Saleh, T.M.1    Connell, B.J.2    Legge, C.3    Cribb, A.E.4
  • 66
    • 4444229212 scopus 로고    scopus 로고
    • Acute effects of 17beta-estradiol on the extracellular concentration of excitatory amino acids and energy metabolites during transient cerebral ischemia in male rats
    • M.F. Ritz, P. Schmidt, and A. Mendelowitsch Acute effects of 17beta-estradiol on the extracellular concentration of excitatory amino acids and energy metabolites during transient cerebral ischemia in male rats Brain Res. 1022 2004 157 163
    • (2004) Brain Res. , vol.1022 , pp. 157-163
    • Ritz, M.F.1    Schmidt, P.2    Mendelowitsch, A.3
  • 68
    • 0028971169 scopus 로고
    • 17-beta estradiol protects neurons from oxidative stress-induced cell death in vitro
    • C. Behl, M. Widmann, T. Trapp, and F. Holsboer 17-beta estradiol protects neurons from oxidative stress-induced cell death in vitro Biochem. Biophys. Res. Commun. 216 1995 473 482
    • (1995) Biochem. Biophys. Res. Commun. , vol.216 , pp. 473-482
    • Behl, C.1    Widmann, M.2    Trapp, T.3    Holsboer, F.4
  • 69
    • 0033497678 scopus 로고    scopus 로고
    • Neuroprotection by estrogens in a mouse model of focal cerebral ischemia and in cultured neurons: Evidence for a receptor-independent antioxidative mechanism
    • C. Culmsee, H. Vedder, A. Ravati, V. Junker, D. Otto, B. Ahlemeyer, J.C. Krieg, and J. Krieglstein Neuroprotection by estrogens in a mouse model of focal cerebral ischemia and in cultured neurons: evidence for a receptor-independent antioxidative mechanism J. Cereb. Blood Flow Metab. 19 1999 1263 1269
    • (1999) J. Cereb. Blood Flow Metab. , vol.19 , pp. 1263-1269
    • Culmsee, C.1    Vedder, H.2    Ravati, A.3    Junker, V.4    Otto, D.5    Ahlemeyer, B.6    Krieg, J.C.7    Krieglstein, J.8
  • 70
    • 0030608841 scopus 로고    scopus 로고
    • 17beta-estradiol attenuates oxidative impairment of synaptic Na+/K+-ATPase activity, glucose transport, and glutamate transport induced by amyloid beta-peptide and iron
    • J.N. Keller, A. Germeyer, J.G. Begley, and M.P. Mattson 17beta-estradiol attenuates oxidative impairment of synaptic Na+/K+-ATPase activity, glucose transport, and glutamate transport induced by amyloid beta-peptide and iron J. Neurosci. Res. 50 1997 522 530
    • (1997) J. Neurosci. Res. , vol.50 , pp. 522-530
    • Keller, J.N.1    Germeyer, A.2    Begley, J.G.3    Mattson, M.P.4
  • 71
    • 0033529941 scopus 로고    scopus 로고
    • The antioxidant neuroprotective effects of estrogens and phenolic compounds are independent from their estrogenic properties
    • B. Moosmann, and C. Behl The antioxidant neuroprotective effects of estrogens and phenolic compounds are independent from their estrogenic properties Proc. Natl. Acad. Sci. U.S.A. 96 1999 8867 8872
    • (1999) Proc. Natl. Acad. Sci. U.S.A. , vol.96 , pp. 8867-8872
    • Moosmann, B.1    Behl, C.2
  • 72
    • 0033016186 scopus 로고    scopus 로고
    • Estrogen hormones reduce lipid peroxidation in cells and tissues of the central nervous system
    • H. Vedder, N. Anthes, G. Stumm, C. Wurz, C. Behl, and J.C. Krieg Estrogen hormones reduce lipid peroxidation in cells and tissues of the central nervous system J. Neurochem. 72 1999 2531 2538
    • (1999) J. Neurochem. , vol.72 , pp. 2531-2538
    • Vedder, H.1    Anthes, N.2    Stumm, G.3    Wurz, C.4    Behl, C.5    Krieg, J.C.6
  • 73
    • 0030605162 scopus 로고    scopus 로고
    • Enhanced oxidative stress in female rat brain after gonadectomy
    • J. Kume-Kick, D.C. Ferris, I. Russo-Menna, and M.E. Rice Enhanced oxidative stress in female rat brain after gonadectomy Brain Res. 738 1996 8 14
    • (1996) Brain Res. , vol.738 , pp. 8-14
    • Kume-Kick, J.1    Ferris, D.C.2    Russo-Menna, I.3    Rice, M.E.4
  • 74
    • 0032563688 scopus 로고    scopus 로고
    • Estrogen-dependent modulation of rat brain ascorbate levels and ischemia-induced ascorbate loss
    • J. Kume-Kick, and M.E. Rice Estrogen-dependent modulation of rat brain ascorbate levels and ischemia-induced ascorbate loss Brain Res. 803 1998 105 113
    • (1998) Brain Res. , vol.803 , pp. 105-113
    • Kume-Kick, J.1    Rice, M.E.2
  • 75
    • 2042454987 scopus 로고    scopus 로고
    • 17beta-estradiol protects oligodendrocytes from cytotoxicity-induced cell death
    • T. Takao, N. Flint, L. Lee, X. Ying, J. Merrill, and K.J. Chandross 17beta-estradiol protects oligodendrocytes from cytotoxicity-induced cell death J. Neurochem. 89 2004 660 673
    • (2004) J. Neurochem. , vol.89 , pp. 660-673
    • Takao, T.1    Flint, N.2    Lee, L.3    Ying, X.4    Merrill, J.5    Chandross, K.J.6
  • 76
    • 0034128362 scopus 로고    scopus 로고
    • Gender differences in acute CNS trauma and stroke: Neuroprotective effects of estrogen and progesterone
    • R.L. Roof, and E.D. Hall Gender differences in acute CNS trauma and stroke: neuroprotective effects of estrogen and progesterone J. Neurotrauma 17 2000 367 388
    • (2000) J. Neurotrauma , vol.17 , pp. 367-388
    • Roof, R.L.1    Hall, E.D.2
  • 77
    • 0030855406 scopus 로고    scopus 로고
    • Progesterone protects against lipid peroxidation following traumatic brain injury in rats
    • R.L. Roof, S.W. Hoffman, and D.G. Stein Progesterone protects against lipid peroxidation following traumatic brain injury in rats Mol. Chem. Neuropathol. 31 1997 1 11
    • (1997) Mol. Chem. Neuropathol. , vol.31 , pp. 1-11
    • Roof, R.L.1    Hoffman, S.W.2    Stein, D.G.3
  • 78
    • 0033199996 scopus 로고    scopus 로고
    • Pathobiology of ischaemic stroke: An integrated view
    • U. Dirnagl, C. Iadecola, and M.A. Moskowitz Pathobiology of ischaemic stroke: an integrated view Trends Neurosci. 22 1999 391 397
    • (1999) Trends Neurosci. , vol.22 , pp. 391-397
    • Dirnagl, U.1    Iadecola, C.2    Moskowitz, M.A.3
  • 79
    • 0030751549 scopus 로고    scopus 로고
    • Estradiol down-regulates LPS-induced cytokine production and NFkB activation in murine macrophages
    • R. Deshpande, H. Khalili, R.G. Pergolizzi, S.D. Michael, and M.D. Chang Estradiol down-regulates LPS-induced cytokine production and NFkB activation in murine macrophages Am. J. Reprod. Immunol. 38 1997 46 54
    • (1997) Am. J. Reprod. Immunol. , vol.38 , pp. 46-54
    • Deshpande, R.1    Khalili, H.2    Pergolizzi, R.G.3    Michael, S.D.4    Chang, M.D.5
  • 80
    • 0032694582 scopus 로고    scopus 로고
    • Estrogen decreases TNF gene expression by blocking JNK activity and the resulting production of c-Jun and JunD
    • S. Srivastava, M.N. Weitzmann, S. Cenci, F.P. Ross, S. Adler, and R. Pacifici Estrogen decreases TNF gene expression by blocking JNK activity and the resulting production of c-Jun and JunD J. Clin. Invest. 104 1999 503 513
    • (1999) J. Clin. Invest. , vol.104 , pp. 503-513
    • Srivastava, S.1    Weitzmann, M.N.2    Cenci, S.3    Ross, F.P.4    Adler, S.5    Pacifici, R.6
  • 81
    • 0344874576 scopus 로고    scopus 로고
    • Estradiol differentially regulates c-Fos after focal cerebral ischemia
    • S.W. Rau, D.B. Dubal, M. Bottner, and P.M. Wise Estradiol differentially regulates c-Fos after focal cerebral ischemia J. Neurosci. 23 2003 10487 10494
    • (2003) J. Neurosci. , vol.23 , pp. 10487-10494
    • Rau, S.W.1    Dubal, D.B.2    Bottner, M.3    Wise, P.M.4
  • 83
    • 0031594466 scopus 로고    scopus 로고
    • Physiological concentrations of 17beta-estradiol inhibit the synthesis of nitric oxide synthase in macrophages via a receptor-mediated system
    • T. Hayashi, K. Yamada, T. Esaki, E. Muto, G. Chaudhuri, and A. Iguchi Physiological concentrations of 17beta-estradiol inhibit the synthesis of nitric oxide synthase in macrophages via a receptor-mediated system J. Cardiovasc. Pharmacol. 31 1998 292 298
    • (1998) J. Cardiovasc. Pharmacol. , vol.31 , pp. 292-298
    • Hayashi, T.1    Yamada, K.2    Esaki, T.3    Muto, E.4    Chaudhuri, G.5    Iguchi, A.6
  • 84
    • 0037036921 scopus 로고    scopus 로고
    • Estrogen inhibits NF kappa B-dependent inflammation in brain endothelium without interfering with I kappa B degradation
    • E. Galea, R. Santizo, D.L. Feinstein, P. Adamsom, J. Greenwood, H.M. Koenig, and D.A. Pelligrino Estrogen inhibits NF kappa B-dependent inflammation in brain endothelium without interfering with I kappa B degradation Neuroreport 13 2002 1469 1472
    • (2002) Neuroreport , vol.13 , pp. 1469-1472
    • Galea, E.1    Santizo, R.2    Feinstein, D.L.3    Adamsom, P.4    Greenwood, J.5    Koenig, H.M.6    Pelligrino, D.A.7
  • 85
    • 2442534125 scopus 로고    scopus 로고
    • Estrogen attenuates nuclear factor-kappa B activation induced by transient cerebral ischemia
    • Y. Wen, S. Yang, R. Liu, E. Perez, K.D. Yi, P. Koulen, and J.W. Simpkins Estrogen attenuates nuclear factor-kappa B activation induced by transient cerebral ischemia Brain Res. 1008 2004 147 154
    • (2004) Brain Res. , vol.1008 , pp. 147-154
    • Wen, Y.1    Yang, S.2    Liu, R.3    Perez, E.4    Yi, K.D.5    Koulen, P.6    Simpkins, J.W.7
  • 86
  • 87
    • 0033951842 scopus 로고    scopus 로고
    • Early and sequential recruitment of apoptotic effectors after focal permanent ischemia in mice
    • C. Guegan, and B. Sola Early and sequential recruitment of apoptotic effectors after focal permanent ischemia in mice Brain Res. 856 2000 93 100
    • (2000) Brain Res. , vol.856 , pp. 93-100
    • Guegan, C.1    Sola, B.2
  • 88
    • 0030884358 scopus 로고    scopus 로고
    • Apoptosis and protein expression after focal cerebral ischemia in rat
    • Y. Li, M. Chopp, C. Powers, and N. Jiang Apoptosis and protein expression after focal cerebral ischemia in rat Brain Res. 765 1997 301 312
    • (1997) Brain Res. , vol.765 , pp. 301-312
    • Li, Y.1    Chopp, M.2    Powers, C.3    Jiang, N.4
  • 89
    • 0029038416 scopus 로고
    • Ultrastructural and light microscopic evidence of apoptosis after middle cerebral artery occlusion in the rat
    • Y. Li, V.G. Sharov, N. Jiang, C. Zaloga, H.N. Sabbah, and M. Chopp Ultrastructural and light microscopic evidence of apoptosis after middle cerebral artery occlusion in the rat Am. J. Pathol. 146 1995 1045 1051
    • (1995) Am. J. Pathol. , vol.146 , pp. 1045-1051
    • Li, Y.1    Sharov, V.G.2    Jiang, N.3    Zaloga, C.4    Sabbah, H.N.5    Chopp, M.6
  • 90
    • 0036138260 scopus 로고    scopus 로고
    • Induction of caspase-activated deoxyribonuclease activity after focal cerebral ischemia and reperfusion
    • Y. Luo, G. Cao, W. Pei, C. O'Horo, S.H. Graham, and J. Chen Induction of caspase-activated deoxyribonuclease activity after focal cerebral ischemia and reperfusion J. Cereb. Blood Flow Metab. 22 2002 15 20
    • (2002) J. Cereb. Blood Flow Metab. , vol.22 , pp. 15-20
    • Luo, Y.1    Cao, G.2    Pei, W.3    O'Horo, C.4    Graham, S.H.5    Chen, J.6
  • 92
    • 0344013490 scopus 로고    scopus 로고
    • Cellular and molecular events underlying ischemia-induced neuronal apoptosis
    • Z. Zheng, H. Zhao, G.K. Steinberg, and M.A. Yenari Cellular and molecular events underlying ischemia-induced neuronal apoptosis Drug News Perspect. 16 2003 497 503
    • (2003) Drug News Perspect. , vol.16 , pp. 497-503
    • Zheng, Z.1    Zhao, H.2    Steinberg, G.K.3    Yenari, M.A.4
  • 94
    • 0032479933 scopus 로고    scopus 로고
    • Modulation of Bcl-2 expression: A potential component of estrogen protection in NT2 neurons
    • C.A. Singer, K.L. Rogers, and D.M. Dorsa Modulation of Bcl-2 expression: a potential component of estrogen protection in NT2 neurons Neuroreport 9 1998 2565 2568
    • (1998) Neuroreport , vol.9 , pp. 2565-2568
    • Singer, C.A.1    Rogers, K.L.2    Dorsa, D.M.3
  • 95
    • 2342630011 scopus 로고    scopus 로고
    • Estrogen receptor subtypes alpha and beta contribute to neuroprotection and increased Bcl-2 expression in primary hippocampal neurons
    • L. Zhao, T.W. Wu, and R.D. Brinton Estrogen receptor subtypes alpha and beta contribute to neuroprotection and increased Bcl-2 expression in primary hippocampal neurons Brain Res. 1010 2004 22 34
    • (2004) Brain Res. , vol.1010 , pp. 22-34
    • Zhao, L.1    Wu, T.W.2    Brinton, R.D.3
  • 99
    • 0033178294 scopus 로고    scopus 로고
    • Estradiol modulates bcl-2 in cerebral ischemia: A potential role for estrogen receptors
    • D.B. Dubal, P.J. Shughrue, M.E. Wilson, I. Merchenthaler, and P.M. Wise Estradiol modulates bcl-2 in cerebral ischemia: a potential role for estrogen receptors J. Neurosci. 19 1999 6385 6393
    • (1999) J. Neurosci. , vol.19 , pp. 6385-6393
    • Dubal, D.B.1    Shughrue, P.J.2    Wilson, M.E.3    Merchenthaler, I.4    Wise, P.M.5
  • 100
    • 0348109349 scopus 로고    scopus 로고
    • Estradiol attenuates programmed cell death after stroke-like injury
    • S.W. Rau, D.B. Dubal, M. Bottner, L.M. Gerhold, and P.M. Wise Estradiol attenuates programmed cell death after stroke-like injury J. Neurosci. 23 2003 11420 11426
    • (2003) J. Neurosci. , vol.23 , pp. 11420-11426
    • Rau, S.W.1    Dubal, D.B.2    Bottner, M.3    Gerhold, L.M.4    Wise, P.M.5
  • 102
    • 0342803689 scopus 로고    scopus 로고
    • Estrogen-induced activation of the mitogen-activated protein kinase cascade in the cerebral cortex of estrogen receptor-alpha knock-out mice
    • M. Singh, G. Setalo Jr., X. Guan, D.E. Frail, and C.D. Toran-Allerand Estrogen-induced activation of the mitogen-activated protein kinase cascade in the cerebral cortex of estrogen receptor-alpha knock-out mice J. Neurosci. 20 2000 1694 1700
    • (2000) J. Neurosci. , vol.20 , pp. 1694-1700
    • Singh, M.1    Setalo Jr., G.2    Guan, X.3    Frail, D.E.4    Toran-Allerand, C.D.5
  • 103
    • 0036173216 scopus 로고    scopus 로고
    • 17-beta-estradiol induces heat shock proteins in brain arteries and potentiates ischemic heat shock protein induction in glia and neurons
    • A. Lu, R.Q. Ran, J. Clark, M. Reilly, A. Nee, and F.R. Sharp 17-beta-estradiol induces heat shock proteins in brain arteries and potentiates ischemic heat shock protein induction in glia and neurons J. Cereb. Blood Flow Metab. 22 2002 183 195
    • (2002) J. Cereb. Blood Flow Metab. , vol.22 , pp. 183-195
    • Lu, A.1    Ran, R.Q.2    Clark, J.3    Reilly, M.4    Nee, A.5    Sharp, F.R.6
  • 104
    • 0028030144 scopus 로고
    • Effects of estrogen replacement on the relative levels of choline acetyltransferase, trkA, and nerve growth factor messenger RNAs in the basal forebrain and hippocampal formation of adult rats
    • R.B. Gibbs, D. Wu, L.B. Hersh, and D.W. Pfaff Effects of estrogen replacement on the relative levels of choline acetyltransferase, trkA, and nerve growth factor messenger RNAs in the basal forebrain and hippocampal formation of adult rats Exp. Neurol. 129 1994 70 80
    • (1994) Exp. Neurol. , vol.129 , pp. 70-80
    • Gibbs, R.B.1    Wu, D.2    Hersh, L.B.3    Pfaff, D.W.4
  • 105
    • 0028144602 scopus 로고
    • Estrogen differentially regulates estrogen and nerve growth factor receptor mRNAs in adult sensory neurons
    • F. Sohrabji, R.C. Miranda, and C.D. Toran-Allerand Estrogen differentially regulates estrogen and nerve growth factor receptor mRNAs in adult sensory neurons J. Neurosci. 14 1994 459 471
    • (1994) J. Neurosci. , vol.14 , pp. 459-471
    • Sohrabji, F.1    Miranda, R.C.2    Toran-Allerand, C.D.3
  • 106
    • 0036813151 scopus 로고    scopus 로고
    • A novel mechanism of dendritic spine plasticity involving estradiol induction of prostaglandin-E2
    • S.K. Amateau, and M.M. McCarthy A novel mechanism of dendritic spine plasticity involving estradiol induction of prostaglandin-E2 J. Neurosci. 22 2002 8586 8596
    • (2002) J. Neurosci. , vol.22 , pp. 8586-8596
    • Amateau, S.K.1    McCarthy, M.M.2
  • 107
    • 0034652324 scopus 로고    scopus 로고
    • Estrogen selectively regulates spine density within the dendritic arbor of rat ventromedial hypothalamic neurons
    • L.H. Calizo, and L.M. Flanagan-Cato Estrogen selectively regulates spine density within the dendritic arbor of rat ventromedial hypothalamic neurons J. Neurosci. 20 2000 1589 1596
    • (2000) J. Neurosci. , vol.20 , pp. 1589-1596
    • Calizo, L.H.1    Flanagan-Cato, L.M.2
  • 109
    • 0034483122 scopus 로고    scopus 로고
    • Culture models for the study of estradiol-induced synaptic plasticity
    • D.D. Murphy, and S.B. Andrews Culture models for the study of estradiol-induced synaptic plasticity J. Neurocytol. 29 2000 411 417
    • (2000) J. Neurocytol. , vol.29 , pp. 411-417
    • Murphy, D.D.1    Andrews, S.B.2
  • 110
    • 0141429106 scopus 로고    scopus 로고
    • Thinking globally, acting locally: Steroid hormone regulation of the dendritic architecture, synaptic connectivity and death of an individual neuron
    • J.C. Weeks Thinking globally, acting locally: steroid hormone regulation of the dendritic architecture, synaptic connectivity and death of an individual neuron Prog. Neurobiol. 70 2003 421 442
    • (2003) Prog. Neurobiol. , vol.70 , pp. 421-442
    • Weeks, J.C.1
  • 111
  • 112
    • 0033118665 scopus 로고    scopus 로고
    • The mitogen-activated protein kinase pathway mediates estrogen neuroprotection after glutamate toxicity in primary cortical neurons
    • C.A. Singer, X.A. Figueroa-Masot, R.H. Batchelor, and D.M. Dorsa The mitogen-activated protein kinase pathway mediates estrogen neuroprotection after glutamate toxicity in primary cortical neurons J. Neurosci. 19 1999 2455 2463
    • (1999) J. Neurosci. , vol.19 , pp. 2455-2463
    • Singer, C.A.1    Figueroa-Masot, X.A.2    Batchelor, R.H.3    Dorsa, D.M.4
  • 113
    • 0032530111 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor mediates estradiol-induced dendritic spine formation in hippocampal neurons
    • D.D. Murphy, N.B. Cole, and M. Segal Brain-derived neurotrophic factor mediates estradiol-induced dendritic spine formation in hippocampal neurons Proc. Natl. Acad. Sci. U.S.A. 95 1998 11412 11417
    • (1998) Proc. Natl. Acad. Sci. U.S.A. , vol.95 , pp. 11412-11417
    • Murphy, D.D.1    Cole, N.B.2    Segal, M.3
  • 114
    • 0028918161 scopus 로고
    • The effect of ovariectomy and estradiol replacement on brain-derived neurotrophic factor messenger ribonucleic acid expression in cortical and hippocampal brain regions of female Sprague-Dawley rats
    • M. Singh, E.M. Meyer, and J.W. Simpkins The effect of ovariectomy and estradiol replacement on brain-derived neurotrophic factor messenger ribonucleic acid expression in cortical and hippocampal brain regions of female Sprague-Dawley rats Endocrinology 136 1995 2320 2324
    • (1995) Endocrinology , vol.136 , pp. 2320-2324
    • Singh, M.1    Meyer, E.M.2    Simpkins, J.W.3
  • 115
    • 0030036767 scopus 로고    scopus 로고
    • The estrogen/neurotrophin connection during neural development: Is co-localization of estrogen receptors with the neurotrophins and their receptors biologically relevant?
    • C.D. Toran-Allerand The estrogen/neurotrophin connection during neural development: is co-localization of estrogen receptors with the neurotrophins and their receptors biologically relevant? Dev. Neurosci. 18 1996 36 48
    • (1996) Dev. Neurosci. , vol.18 , pp. 36-48
    • Toran-Allerand, C.D.1
  • 116
    • 0029917449 scopus 로고    scopus 로고
    • Mechanisms of estrogen action during neural development: Mediation by interactions with the neurotrophins and their receptors?
    • C.D. Toran-Allerand Mechanisms of estrogen action during neural development: mediation by interactions with the neurotrophins and their receptors? J. Steroid Biochem. Mol. Biol. 56 1996 169 178
    • (1996) J. Steroid Biochem. Mol. Biol. , vol.56 , pp. 169-178
    • Toran-Allerand, C.D.1
  • 117
    • 0025411855 scopus 로고
    • Gonadal steroids regulate dendritic spine density in hippocampal pyramidal cells in adulthood
    • E. Gould, C.S. Woolley, M. Frankfurt, and B.S. McEwen Gonadal steroids regulate dendritic spine density in hippocampal pyramidal cells in adulthood J. Neurosci. 10 1990 1286 1291
    • (1990) J. Neurosci. , vol.10 , pp. 1286-1291
    • Gould, E.1    Woolley, C.S.2    Frankfurt, M.3    McEwen, B.S.4
  • 123
    • 0037201172 scopus 로고    scopus 로고
    • Estradiol and progesterone modify microtubule-associated protein 2 content in the rat hippocampus
    • A. Reyna-Neyra, I. Camacho-Arroyo, P. Ferrera, and C. Arias Estradiol and progesterone modify microtubule-associated protein 2 content in the rat hippocampus Brain Res. Bull. 58 2002 607 612
    • (2002) Brain Res. Bull. , vol.58 , pp. 607-612
    • Reyna-Neyra, A.1    Camacho-Arroyo, I.2    Ferrera, P.3    Arias, C.4
  • 124
    • 0034480270 scopus 로고    scopus 로고
    • Estradiol attenuation of beta-amyloid-induced toxicity: A comparison of MTT and calcein AM assays
    • P.S. Green, E.J. Perez, T. Calloway, and J.W. Simpkins Estradiol attenuation of beta-amyloid-induced toxicity: a comparison of MTT and calcein AM assays J. Neurocytol. 29 2000 419 423
    • (2000) J. Neurocytol. , vol.29 , pp. 419-423
    • Green, P.S.1    Perez, E.J.2    Calloway, T.3    Simpkins, J.W.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.