메뉴 건너뛰기




Volumn 19, Issue 8, 2000, Pages 1784-1793

Polyunsaturated fatty acids are potent neuroprotectors

Author keywords

Background K+ channels; Epilepsy; Excitotoxicity; Ischemia; Polyunsaturated fatty acids

Indexed keywords

ARACHIDONIC ACID; DOCOSAHEXAENOIC ACID; GLUTAMATE RECEPTOR ANTAGONIST; KAINIC ACID; LINOLENIC ACID; NEUROPROTECTIVE AGENT; POLYUNSATURATED FATTY ACID; POSTSYNAPTIC RECEPTOR; POTASSIUM CHANNEL; POTASSIUM CHANNEL STIMULATING AGENT; PRESYNAPTIC RECEPTOR;

EID: 0034678889     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/19.8.1784     Document Type: Article
Times cited : (438)

References (53)
  • 1
    • 0025354736 scopus 로고
    • Potassium channel activators abolish excitotoxicity in cultured hippocampal pyramidal neurons
    • Abele, A.E. and Miller, R.J. (1990) Potassium channel activators abolish excitotoxicity in cultured hippocampal pyramidal neurons. Neurosci. Lett., 115, 195-200.
    • (1990) Neurosci. Lett. , vol.115 , pp. 195-200
    • Abele, A.E.1    Miller, R.J.2
  • 2
    • 0025218770 scopus 로고
    • Excitotoxicity induced by enhanced excitatory neurotransmission in cultured hippocampal pyramidal neurons
    • Abele, A.E., Scholz, K.P., Scholz, W.K. and Miller, R.J. (1990) Excitotoxicity induced by enhanced excitatory neurotransmission in cultured hippocampal pyramidal neurons. Neuron, 4, 413-419.
    • (1990) Neuron , vol.4 , pp. 413-419
    • Abele, A.E.1    Scholz, K.P.2    Scholz, W.K.3    Miller, R.J.4
  • 4
    • 0030900752 scopus 로고    scopus 로고
    • Ionotropic glutamate receptors: New types and new concepts
    • Barnard, E.A. (1997) Ionotropic glutamate receptors: new types and new concepts. Trends Pharmacol. Sci., 18, 141-148.
    • (1997) Trends Pharmacol. Sci. , vol.18 , pp. 141-148
    • Barnard, E.A.1
  • 5
    • 0028016077 scopus 로고
    • Glutamate receptors and the induction of excitotoxic neuronal death
    • Choi, D.W. (1994) Glutamate receptors and the induction of excitotoxic neuronal death. Prog. Brain Res., 100, 47-51.
    • (1994) Prog. Brain Res. , vol.100 , pp. 47-51
    • Choi, D.W.1
  • 6
    • 0033216115 scopus 로고    scopus 로고
    • + channels in hippocampal CA1 pyramidal neurons
    • + channels in hippocampal CA1 pyramidal neurons. J. Neurosci., 19, 8163-8171.
    • (1999) J. Neurosci. , vol.19 , pp. 8163-8171
    • Colbert, C.M.1    Pan, E.2
  • 9
    • 0025883589 scopus 로고
    • Excitatory amino acid receptors, neural membrane phospholipid metabolism and neurological disorders
    • Farooqui, A.A. and Horrocks, L.A. (1991) Excitatory amino acid receptors, neural membrane phospholipid metabolism and neurological disorders. Brain Res. Rev., 16, 171-191.
    • (1991) Brain Res. Rev. , vol.16 , pp. 171-191
    • Farooqui, A.A.1    Horrocks, L.A.2
  • 12
    • 0027370953 scopus 로고
    • Arachidonic acid inhibits sodium currents and synaptic transmission in cultured striatal neurons
    • Fraser, D.D., Hoehn, K., Weiss, S. and MacViar, B.A. (1993) Arachidonic acid inhibits sodium currents and synaptic transmission in cultured striatal neurons. Neuron, 11, 633-644.
    • (1993) Neuron , vol.11 , pp. 633-644
    • Fraser, D.D.1    Hoehn, K.2    Weiss, S.3    MacViar, B.A.4
  • 13
    • 0026648674 scopus 로고
    • Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation
    • Gavrieli, Y., Sherman, Y. and Ben-Sason, S.A. (1992) Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J. Cell Biol., 119, 493-501.
    • (1992) J. Cell Biol. , vol.119 , pp. 493-501
    • Gavrieli, Y.1    Sherman, Y.2    Ben-Sason, S.A.3
  • 14
    • 0030840881 scopus 로고    scopus 로고
    • High affinity glutamate transporters: Regulation of expression and activity
    • Gegelashvili, G. and Schousboe, A. (1997) High affinity glutamate transporters: regulation of expression and activity. Mol. Pharmacol., 52, 6-15.
    • (1997) Mol. Pharmacol. , vol.52 , pp. 6-15
    • Gegelashvili, G.1    Schousboe, A.2
  • 16
    • 0027443562 scopus 로고
    • + channel openers prevent global ischemia-induced expression of c-fos, c-jun, heat shock protein and amyloid β-protein precursor genes and neuronal death in rat hippocampus
    • + channel openers prevent global ischemia-induced expression of c-fos, c-jun, heat shock protein and amyloid β-protein precursor genes and neuronal death in rat hippocampus. Proc. Natl Acad. Sci. USA, 90, 9431-9435.
    • (1993) Proc. Natl Acad. Sci. USA , vol.90 , pp. 9431-9435
    • Heurteaux, C.1    Bertaina, V.2    Widmann, C.3    Lazdunski, M.4
  • 17
    • 0001455179 scopus 로고    scopus 로고
    • Fish consumption and major depression
    • Hibbeln, J.R. (1998) Fish consumption and major depression. Lancet, 351, 1210-1213.
    • (1998) Lancet , vol.351 , pp. 1210-1213
    • Hibbeln, J.R.1
  • 19
    • 0030957326 scopus 로고    scopus 로고
    • Arachidonic acid inhibits transient potassium currents and broadens action potentials during electrographic seizures in hippocampal pyramidal and inhibitory interneurons
    • Keros, S. and McBain, C.J. (1997) Arachidonic acid inhibits transient potassium currents and broadens action potentials during electrographic seizures in hippocampal pyramidal and inhibitory interneurons. J. Neurosci., 17, 3476-3487.
    • (1997) J. Neurosci. , vol.17 , pp. 3476-3487
    • Keros, S.1    McBain, C.J.2
  • 20
    • 0024384172 scopus 로고
    • Potassium channels in cardiac cells activated by arachidonic acid and phospholipids
    • Kim, D. and Clapham, D.E. (1989) Potassium channels in cardiac cells activated by arachidonic acid and phospholipids. Science, 244, 1174-1179.
    • (1989) Science , vol.244 , pp. 1174-1179
    • Kim, D.1    Clapham, D.E.2
  • 22
    • 0022483433 scopus 로고
    • A reversible type of neuronal injury following ischemia in the gerbil hippocampus
    • Kirino, T., Tamura, A. and Sano, K. (1986) A reversible type of neuronal injury following ischemia in the gerbil hippocampus. Stroke, 17, 455-459.
    • (1986) Stroke , vol.17 , pp. 455-459
    • Kirino, T.1    Tamura, A.2    Sano, K.3
  • 23
    • 0023221068 scopus 로고
    • Quantitative determination of glutamate mediated cortical neuronal injury in cell culture by lactate dehydrogenase efflux assay
    • Koh, J.Y. and Choi, D.W. (1987) Quantitative determination of glutamate mediated cortical neuronal injury in cell culture by lactate dehydrogenase efflux assay. J. Neurosci. Methods, 20, 83-90.
    • (1987) J. Neurosci. Methods , vol.20 , pp. 83-90
    • Koh, J.Y.1    Choi, D.W.2
  • 24
    • 0027221998 scopus 로고
    • NMDA-dependent superoxide production and neurotoxicity
    • Lafon-Cazal, M., Pietri, S., Culcasi, M. and Bockaert, J. (1993) NMDA-dependent superoxide production and neurotoxicity. Nature, 364, 535-537.
    • (1993) Nature , vol.364 , pp. 535-537
    • Lafon-Cazal, M.1    Pietri, S.2    Culcasi, M.3    Bockaert, J.4
  • 26
    • 0030928648 scopus 로고    scopus 로고
    • The potassium channel opener (-)-cromakalim prevents glutamate-induced cell death in hippocampal neurons
    • Lauritzen, I., De Weille, J.R. and Lazdunski, M. (1997) The potassium channel opener (-)-cromakalim prevents glutamate-induced cell death in hippocampal neurons. J. Neurochem., 69, 1570-1579.
    • (1997) J. Neurochem. , vol.69 , pp. 1570-1579
    • Lauritzen, I.1    De Weille, J.R.2    Lazdunski, M.3
  • 27
    • 0030057966 scopus 로고    scopus 로고
    • Prevention of cardiac sudden death by n-3 fatty acids: A review of the evidence
    • Leaf, A. and Kang, J.X. (1996) Prevention of cardiac sudden death by n-3 fatty acids: a review of the evidence. J. Intern. Med., 240, 5-12.
    • (1996) J. Intern. Med. , vol.240 , pp. 5-12
    • Leaf, A.1    Kang, J.X.2
  • 28
    • 0032725468 scopus 로고    scopus 로고
    • The antiarrhythmic and anticonvulsant effects of dietary n-3 fatty acids
    • Leaf, A., Kang, J.X., Xiao, Y.-F., Billman, G.E. and Voskuyl, R.A. (1999) The antiarrhythmic and anticonvulsant effects of dietary n-3 fatty acids. J. Membr. Biol., 172, 1-11.
    • (1999) J. Membr. Biol. , vol.172 , pp. 1-11
    • Leaf, A.1    Kang, J.X.2    Xiao, Y.-F.3    Billman, G.E.4    Voskuyl, R.A.5
  • 31
    • 0019501929 scopus 로고
    • Kainic acid induced limbic seizures: Metabolic, behavioral, electroencephalographic and neuropathological correlates
    • Lothman, E.W. and Collins, R.C. (1981) Kainic acid induced limbic seizures: metabolic, behavioral, electroencephalographic and neuropathological correlates. Brain Res., 218, 299-318.
    • (1981) Brain Res. , vol.218 , pp. 299-318
    • Lothman, E.W.1    Collins, R.C.2
  • 33
    • 0028074765 scopus 로고
    • Modulation of ion channels by arachidonic acid
    • Meves, H. (1994) Modulation of ion channels by arachidonic acid. Prog. Neurobiol., 43, 175-186.
    • (1994) Prog. Neurobiol. , vol.43 , pp. 175-186
    • Meves, H.1
  • 34
    • 0026570085 scopus 로고
    • Potentiation of NMDA receptor currents by arachidonic acid
    • Miller, B., Sarantis, M., Traynelis, S.F. and Attwell, D. (1992) Potentiation of NMDA receptor currents by arachidonic acid. Nature, 355, 722-725.
    • (1992) Nature , vol.355 , pp. 722-725
    • Miller, B.1    Sarantis, M.2    Traynelis, S.F.3    Attwell, D.4
  • 35
    • 0022362589 scopus 로고
    • 2-amino-6-trifluoromethoxy benzothiazole, a possible antagonist of excitatory amino acid neurotransmission. I. Anticonvulsant properties
    • Mizoule, J., Meldrum, B., Mazadier, M., Croucher, M., Ollat, C., Uzan, A., Legrand, J.J., Gueremy, C. and Fur, G.L. (1985) 2-amino-6-trifluoromethoxy benzothiazole, a possible antagonist of excitatory amino acid neurotransmission. I. Anticonvulsant properties. Neuropharmacology, 24, 767-773.
    • (1985) Neuropharmacology , vol.24 , pp. 767-773
    • Mizoule, J.1    Meldrum, B.2    Mazadier, M.3    Croucher, M.4    Ollat, C.5    Uzan, A.6    Legrand, J.J.7    Gueremy, C.8    Fur, G.L.9
  • 36
    • 0017844923 scopus 로고
    • Intraventricular kainic acid preferentially destroys hippocampal pyramidal cells
    • Nadler, J.V., Perry, B.W. and Cotman, C.W. (1978) Intraventricular kainic acid preferentially destroys hippocampal pyramidal cells. Nature, 271, 676-677.
    • (1978) Nature , vol.271 , pp. 676-677
    • Nadler, J.V.1    Perry, B.W.2    Cotman, C.W.3
  • 37
    • 0030966401 scopus 로고    scopus 로고
    • Prevention of cardiac arrhythmia by dietary (n-3) polyunsaturated fatty acids and their mechanism of action
    • Nair, S.S., Leitch, J.W., Falconer, J. and Garg, M.L. (1997) Prevention of cardiac arrhythmia by dietary (n-3) polyunsaturated fatty acids and their mechanism of action. J. Nutr., 127, 383-393.
    • (1997) J. Nutr. , vol.127 , pp. 383-393
    • Nair, S.S.1    Leitch, J.W.2    Falconer, J.3    Garg, M.L.4
  • 38
    • 0028210975 scopus 로고
    • Facilitatory effect of docosahexaenoic acid on N-methyl-D-aspartate response in pyramidal neurones of rat cerebral cortex
    • Nishikawa, M., Kimura, S. and Akaike, .N. (1994) Facilitatory effect of docosahexaenoic acid on N-methyl-D-aspartate response in pyramidal neurones of rat cerebral cortex. J. Physiol., 475, 83-93.
    • (1994) J. Physiol. , vol.475 , pp. 83-93
    • Nishikawa, M.1    Kimura, S.2    Akaike, N.3
  • 39
    • 0033000747 scopus 로고    scopus 로고
    • Dietary fatty acids and coronary heart disease
    • Nordoy, A. (1999) Dietary fatty acids and coronary heart disease. Lipids, 34, S19-S22.
    • (1999) Lipids , vol.34
    • Nordoy, A.1
  • 42
    • 0018347695 scopus 로고
    • A new model of bilateral hemispheric ischemia in the unanesthetized rat
    • Pulsinelli, W.A. and Brierley, J.B. (1979) A new model of bilateral hemispheric ischemia in the unanesthetized rat. Stroke, 10, 267-272.
    • (1979) Stroke , vol.10 , pp. 267-272
    • Pulsinelli, W.A.1    Brierley, J.B.2
  • 43
    • 0026498034 scopus 로고
    • Potassium channel openers: Pharmacological and clinical aspects
    • Quast, U. (1992) Potassium channel openers: pharmacological and clinical aspects. Fundam. Clin. Pharmacol., 6, 279-293.
    • (1992) Fundam. Clin. Pharmacol. , vol.6 , pp. 279-293
    • Quast, U.1
  • 45
    • 0025372182 scopus 로고
    • Magnesium removal induces paroxysmal neuronal firing and NMDA receptor-mediated neuronal degeneration in cortical cultures
    • Rose, K., Christine, C.W. and Choi, D.W. (1990) Magnesium removal induces paroxysmal neuronal firing and NMDA receptor-mediated neuronal degeneration in cortical cultures. Neurosci. Lett., 115, 313-317.
    • (1990) Neurosci. Lett. , vol.115 , pp. 313-317
    • Rose, K.1    Christine, C.W.2    Choi, D.W.3
  • 46
    • 0025881551 scopus 로고
    • Selective vulnerability of the hippocampus in brain ischemia
    • Schmidt-Kastner, R. and Freund, T.F. (1991) Selective vulnerability of the hippocampus in brain ischemia. Neuroscience, 40, 599-636.
    • (1991) Neuroscience , vol.40 , pp. 599-636
    • Schmidt-Kastner, R.1    Freund, T.F.2
  • 47
    • 0001607156 scopus 로고
    • Preparation of primary cultures of mouse (rat) cerebellar granule neurons
    • Shahar, A., de Vellis, J., Vernadakis, A. and Haber, B. (eds). Alan R. Liss, New York, NY
    • Schousboe, A., Meier, E., Drejer, J. and Hertz, L. (1989) Preparation of primary cultures of mouse (rat) cerebellar granule neurons. In Shahar, A., de Vellis, J., Vernadakis, A. and Haber, B. (eds). A Dissection and Tissue Culture Manual of the Nervous System. Alan R. Liss, New York, NY, pp. 203-206.
    • (1989) A Dissection and Tissue Culture Manual of the Nervous System , pp. 203-206
    • Schousboe, A.1    Meier, E.2    Drejer, J.3    Hertz, L.4
  • 48
    • 0009674385 scopus 로고
    • Brain injury: Neurochemical aspects
    • Becker, D.P. and Povlishock, J.T. (eds). William Byrd Press, Richmond, VA
    • Siesjö, B.K. and Wieloch, T. (1985) Brain injury: neurochemical aspects. In Becker, D.P. and Povlishock, J.T. (eds), System Trauma. William Byrd Press, Richmond, VA, pp. 513-532.
    • (1985) System Trauma , pp. 513-532
    • Siesjö, B.K.1    Wieloch, T.2
  • 52
    • 0032845896 scopus 로고    scopus 로고
    • Polyunsaturated fatty acids modify mouse hippocampal neuronal excitability during excitotoxic or convulsant stimulation
    • Xiao, Y.-F. and Li, X. (1999) Polyunsaturated fatty acids modify mouse hippocampal neuronal excitability during excitotoxic or convulsant stimulation. Brain Res., 846, 112-121.
    • (1999) Brain Res. , vol.846 , pp. 112-121
    • Xiao, Y.-F.1    Li, X.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.