-
1
-
-
0035921419
-
Impaired skin wound healing in peroxisome proliferator-activated receptor (PPAR)alpha and PPARbeta mutant mice
-
Michalik, L., et al. 2001. Impaired skin wound healing in peroxisome proliferator-activated receptor (PPAR)alpha and PPARbeta mutant mice. J. Cell Biol. 154:799-814.
-
(2001)
J. Cell Biol.
, vol.154
, pp. 799-814
-
-
Michalik, L.1
-
2
-
-
0037039374
-
Effects of peroxisome proliferator-activated receptor delta on placentation, adiposity, and colorectal cancer
-
Barak, Y., et al. 2002. Effects of peroxisome proliferator-activated receptor delta on placentation, adiposity, and colorectal cancer. Proc. Natl. Acad. Sci. U. S. A. 99:303-308.
-
(2002)
Proc. Natl. Acad. Sci. U. S. A.
, vol.99
, pp. 303-308
-
-
Barak, Y.1
-
3
-
-
3242690411
-
Peroxisome-proliferator-activated receptor (PPAR)-gamma activation stimulates keratinocyte differentiation
-
Mao-Qiang, M., et al. 2004. Peroxisome-proliferator-activated receptor (PPAR)-gamma activation stimulates keratinocyte differentiation. J. Invest. Dermatol. 123:305-312.
-
(2004)
J. Invest. Dermatol.
, vol.123
, pp. 305-312
-
-
Mao-Qiang, M.1
-
4
-
-
0028003839
-
Regulation of the peroxisome proliferator-activated receptor alpha gene by glucocorticoids
-
Lemberger, T., et al. 1994. Regulation of the peroxisome proliferator-activated receptor alpha gene by glucocorticoids. J. Biol. Chem. 269:24527-24530.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 24527-24530
-
-
Lemberger, T.1
-
5
-
-
1442308951
-
Critical roles of the nuclear receptor PPARbeta (peroxisome-proliferator- activated receptor beta) in skin wound healing
-
Tan, N.S., Michalik, L., Di-Poi, N., Desvergne, B., and Wahli, W. 2004. Critical roles of the nuclear receptor PPARbeta (peroxisome-proliferator- activated receptor beta) in skin wound healing. Biochem. Soc. Trans. 32:97-102.
-
(2004)
Biochem. Soc. Trans.
, vol.32
, pp. 97-102
-
-
Tan, N.S.1
Michalik, L.2
Di-Poi, N.3
Desvergne, B.4
Wahli, W.5
-
6
-
-
0035893364
-
Critical roles of PPAR beta/delta in keratinocyte response to inflammation
-
Tan, N.S., et al. 2001. Critical roles of PPAR beta/delta in keratinocyte response to inflammation. Genes Dev. 15:3263-3277.
-
(2001)
Genes Dev.
, vol.15
, pp. 3263-3277
-
-
Tan, N.S.1
-
7
-
-
0036771764
-
Antiapoptotic role of PPARbeta in keratinocytes via transcriptional control of the Akt1 signaling pathway
-
Di-Poi, N., Tan, N.S., Michalik, L., Wahli, W., and Desvergne, B. 2002. Antiapoptotic role of PPARbeta in keratinocytes via transcriptional control of the Akt1 signaling pathway. Mol. Cell. 10:721-733.
-
(2002)
Mol. Cell.
, vol.10
, pp. 721-733
-
-
Di-Poi, N.1
Tan, N.S.2
Michalik, L.3
Wahli, W.4
Desvergne, B.5
-
8
-
-
9144251051
-
Essential role of Smad3 in the inhibition of inflammation-induced PPARbeta/delta expression
-
Tan, N.S., et al. 2004. Essential role of Smad3 in the inhibition of inflammation-induced PPARbeta/delta expression. EMBO J. 23:4211-4221.
-
(2004)
EMBO J.
, vol.23
, pp. 4211-4221
-
-
Tan, N.S.1
-
9
-
-
32644487946
-
Transcriptional repression of peroxisome proliferator-activated receptor beta/delta in murine keratinocytes by CCAAT/enhancer-binding proteins
-
Di-Poi, N., Desvergne, B., Michalik, L., and Wahli, W. 2005. Transcriptional repression of peroxisome proliferator-activated receptor beta/delta in murine keratinocytes by CCAAT/enhancer-binding proteins. J. Biol. Chem. 280:38700-38710.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 38700-38710
-
-
Di-Poi, N.1
Desvergne, B.2
Michalik, L.3
Wahli, W.4
-
10
-
-
3242776230
-
Endothelial injury and dysfunction: Role in the extension phase of acute renal failure
-
Molitoris, B.A., and Sutton, T.A. 2004. Endothelial injury and dysfunction: role in the extension phase of acute renal failure. Kidney Int. 66:496-499.
-
(2004)
Kidney Int.
, vol.66
, pp. 496-499
-
-
Molitoris, B.A.1
Sutton, T.A.2
-
11
-
-
0034169551
-
Etomoxir-induced PPARalpha-modulated enzymes protect during acute renal failure
-
Portilla, D., et al. 2000. Etomoxir-induced PPARalpha-modulated enzymes protect during acute renal failure. Am. J. Physiol. Renal Physiol. 278:F667-F675.
-
(2000)
Am. J. Physiol. Renal Physiol.
, vol.278
-
-
Portilla, D.1
-
13
-
-
22344434801
-
Anti-inflammatory effect of fibrate protects from cisplatin-induced ARF
-
Li, S., Gokden, N., Okusa, M.D., Bhatt, R., and Portilla, D. 2005. Anti-inflammatory effect of fibrate protects from cisplatin-induced ARF. Am. J. Physiol. Renal Physiol. 289:F469-F480.
-
(2005)
Am. J. Physiol. Renal Physiol.
, vol.289
-
-
Li, S.1
Gokden, N.2
Okusa, M.D.3
Bhatt, R.4
Portilla, D.5
-
14
-
-
6344285851
-
PPAR-alpha ligand ameliorates acute renal failure by reducing cisplatin-induced increased expression of renal endonuclease G
-
Li, S., et al. 2004. PPAR-alpha ligand ameliorates acute renal failure by reducing cisplatin-induced increased expression of renal endonuclease G. Am. J. Physiol. Renal Physiol. 287:F990-F998.
-
(2004)
Am. J. Physiol. Renal Physiol.
, vol.287
-
-
Li, S.1
-
15
-
-
27944442216
-
Peroxisome proliferator-activated receptor beta/delta exerts a strong protection from ischemic acute renal failure
-
Letavernier, E., et al. 2005. Peroxisome proliferator-activated receptor beta/delta exerts a strong protection from ischemic acute renal failure. J. Am. Soc. Nephrol. 16:2395-2402.
-
(2005)
J. Am. Soc. Nephrol.
, vol.16
, pp. 2395-2402
-
-
Letavernier, E.1
-
16
-
-
28544436514
-
Protective effect of peroxisome proliferator activated receptor gamma agonists on diabetic and non-diabetic renal diseases
-
Chung, B.H., et al. 2005. Protective effect of peroxisome proliferator activated receptor gamma agonists on diabetic and non-diabetic renal diseases. Nephrology (Carlton). 10(Suppl. 2):S40-S43.
-
(2005)
Nephrology (Carlton)
, vol.10
, Issue.2 SUPPL.
-
-
Chung, B.H.1
-
17
-
-
11844278455
-
Peroxisome proliferator-activated receptors gamma ligands and ischemia and reperfusion injury
-
Cuzzocrea, S. 2004. Peroxisome proliferator-activated receptors gamma ligands and ischemia and reperfusion injury. Vascul. Pharmacol. 41:187-195.
-
(2004)
Vascul. Pharmacol.
, vol.41
, pp. 187-195
-
-
Cuzzocrea, S.1
-
18
-
-
16644377741
-
Peroxisome proliferator-activated receptor family and its relationship to renal complications of the metabolic syndrome
-
Guan, Y. 2004. Peroxisome proliferator-activated receptor family and its relationship to renal complications of the metabolic syndrome. J. Am. Soc. Nephrol. 15:2801-2815.
-
(2004)
J. Am. Soc. Nephrol.
, vol.15
, pp. 2801-2815
-
-
Guan, Y.1
-
19
-
-
26844496791
-
PPARgamma agonists exert antifibrotic effects in renal tubular cells exposed to high glucose
-
Panchapakesan, U., Sumual, S., Pollock, C.A., and Chen, X. 2005. PPARgamma agonists exert antifibrotic effects in renal tubular cells exposed to high glucose. Am. J. Physiol. Renal Physiol. 289:F1153-F1158.
-
(2005)
Am. J. Physiol. Renal Physiol.
, vol.289
-
-
Panchapakesan, U.1
Sumual, S.2
Pollock, C.A.3
Chen, X.4
-
20
-
-
2342473267
-
Pioglitazone increases renal tubular cell albumin uptake but limits proinflammatory and fibrotic responses
-
Zafiriou, S., Stanners, S.R., Polhill, T.S., Poronnik, P., and Pollock, C.A. 2004. Pioglitazone increases renal tubular cell albumin uptake but limits proinflammatory and fibrotic responses. Kidney Int. 65:1647-1653.
-
(2004)
Kidney Int.
, vol.65
, pp. 1647-1653
-
-
Zafiriou, S.1
Stanners, S.R.2
Polhill, T.S.3
Poronnik, D.4
Pollock, C.A.5
-
21
-
-
0043074737
-
Agonists of peroxisome-proliferator activated receptor-gamma reduce renal ischemia/reperfusion injury
-
Sivarajah, A., et al. 2003. Agonists of peroxisome-proliferator activated receptor-gamma reduce renal ischemia/reperfusion injury. Am. J. Nephrol. 23:267-276.
-
(2003)
Am. J. Nephrol.
, vol.23
, pp. 267-276
-
-
Sivarajah, A.1
-
22
-
-
0036086797
-
Upregulation of type I collagen by TGF-beta in mesangial cells is blocked by PPARgamma activation
-
Zheng, F., et al. 2002. Upregulation of type I collagen by TGF-beta in mesangial cells is blocked by PPARgamma activation. Am. J. Physiol. Renal Physiol. 282:F639-F648.
-
(2002)
Am. J. Physiol. Renal Physiol.
, vol.282
-
-
Zheng, F.1
-
23
-
-
10744231560
-
The cyclopentenone prostaglandin 15-deoxy-delta(12,14)-prostaglandin J2 ameliorates ischemic acute renal failure
-
Chatterjee, P.K., et al. 2004. The cyclopentenone prostaglandin 15-deoxy-delta(12,14)-prostaglandin J2 ameliorates ischemic acute renal failure. Cardiovasc. Res. 61:630-643.
-
(2004)
Cardiovasc. Res.
, vol.61
, pp. 630-643
-
-
Chatterjee, P.K.1
-
24
-
-
0033922644
-
Reperfusion injury significantly impacts clinical outcome after pulmonary transplantation
-
King, R.C., et al. 2000. Reperfusion injury significantly impacts clinical outcome after pulmonary transplantation. Ann. Thorac. Surg. 69:1681-1685.
-
(2000)
Ann. Thorac. Surg.
, vol.69
, pp. 1681-1685
-
-
King, R.C.1
-
25
-
-
1642401329
-
Protective effects of preischemic treatment with pioglitazone, a peroxisome proliferator-activated receptor-gamma ligand, on lung ischemia-reperfusion injury in rats
-
Ito, K., et al. 2004. Protective effects of preischemic treatment with pioglitazone, a peroxisome proliferator-activated receptor-gamma ligand, on lung ischemia-reperfusion injury in rats. Eur. J. Cardiothorac. Surg. 25:530-536.
-
(2004)
Eur. J. Cardiothorac. Surg.
, vol.25
, pp. 530-536
-
-
Ito, K.1
-
26
-
-
0036901274
-
Peroxisome proliferator-activated receptor-gamma (PPAR-gamma) activation suppresses ischemic induction of Egr-1 and its inflammatory gene targets
-
Okada, M., Yan, S.F., and Pinsky, D.J. 2002. Peroxisome proliferator-activated receptor-gamma (PPAR-gamma) activation suppresses ischemic induction of Egr-1 and its inflammatory gene targets. FASEB J. 16:1861-1868.
-
(2002)
FASEB J.
, vol.16
, pp. 1861-1868
-
-
Okada, M.1
Yan, S.F.2
Pinsky, D.J.3
-
28
-
-
0034827655
-
Bleomycin-induced pneumonitis
-
Sleijfer, S. 2001. Bleomycin-induced pneumonitis. Chest. 120:617-624.
-
(2001)
Chest
, vol.120
, pp. 617-624
-
-
Sleijfer, S.1
-
29
-
-
18844458812
-
PPARgamma agonists inhibit TGF-beta induced pulmonary myofibroblast differentiation and collagen production: Implications for therapy of lung fibrosis
-
Burgess, H.A., et al. 2005. PPARgamma agonists inhibit TGF-beta induced pulmonary myofibroblast differentiation and collagen production: implications for therapy of lung fibrosis. Am. J. Physiol. Lung Cell. Mol. Physiol. 288:L1146-L1153.
-
(2005)
Am. J. Physiol. Lung Cell. Mol. Physiol.
, vol.288
-
-
Burgess, H.A.1
-
30
-
-
13844294429
-
Effect of rosiglitazone and 15-deoxy-delta12,14-prostaglandin J2 on bleomycin-induced lung injury
-
Genovese, T., et al. 2005. Effect of rosiglitazone and 15-deoxy-delta12,14-prostaglandin J2 on bleomycin-induced lung injury. Eur. Respir. J. 25:225-234.
-
(2005)
Eur. Respir. J.
, vol.25
, pp. 225-234
-
-
Genovese, T.1
-
31
-
-
0032421462
-
Intestinal (mesenteric) vasculopathy. II. Ischemic colitis and chronic mesenteric ischemia
-
Cappell, M.S. 1998. Intestinal (mesenteric) vasculopathy. II. Ischemic colitis and chronic mesenteric ischemia [review]. Gastroenterol. Clin. North Am. 27:827-860, vi.
-
(1998)
Gastroenterol. Clin. North Am.
, vol.27
, pp. 827-860
-
-
Cappell, M.S.1
-
32
-
-
0035127894
-
Endogenous PPAR gamma mediates anti-inflammatory activity in murine ischemia-reperfusion injury
-
Nakajima, A., et al. 2001. Endogenous PPAR gamma mediates anti-inflammatory activity in murine ischemia-reperfusion injury. Gastroenterology. 120:460-469.
-
(2001)
Gastroenterology
, vol.120
, pp. 460-469
-
-
Nakajima, A.1
-
33
-
-
0036920167
-
Suppression of intestinal ischemia-reperfusion injury by a specific peroxisome proliferator-activated receptor-gamma ligand, pioglitazone, in rats
-
Naito, Y., et al. 2002. Suppression of intestinal ischemia-reperfusion injury by a specific peroxisome proliferator-activated receptor-gamma ligand, pioglitazone, in rats. Redox Rep. 7:294-299.
-
(2002)
Redox Rep.
, vol.7
, pp. 294-299
-
-
Naito, Y.1
-
34
-
-
10744223174
-
Rosiglitazone and 15-deoxy-delta12,14-prostaglandin J2, ligands of the peroxisome proliferator-activated receptor-gamma (PPAR-gamma), reduce ischaemia/reperfusion injury of the gut
-
Cuzzocrea, S., et al. 2003. Rosiglitazone and 15-deoxy-delta12,14- prostaglandin J2, ligands of the peroxisome proliferator-activated receptor-gamma (PPAR-gamma), reduce ischaemia/reperfusion injury of the gut. Br. J. Pharmacol. 140:366-376.
-
(2003)
Br. J. Pharmacol.
, vol.140
, pp. 366-376
-
-
Cuzzocrea, S.1
-
35
-
-
7944235591
-
WY 14643, a potent exogenous PPAR-alpha ligand, reduces intestinal injury associated with splanchnic artery occlusion shock
-
Cuzzocrea, S., et al. 2004. WY 14643, a potent exogenous PPAR-alpha ligand, reduces intestinal injury associated with splanchnic artery occlusion shock. Shock. 22:340-346.
-
(2004)
Shock
, vol.22
, pp. 340-346
-
-
Cuzzocrea, S.1
-
36
-
-
33645802403
-
Differential induction of PPAR gamma by luminal glutamine and iNOS by luminal arginine in the rodent post ischemic small bowel
-
doi:10.1152/ajpgi.00248.2005
-
Sato, N., et al. 2005. Differential induction of PPAR gamma by luminal glutamine and iNOS by luminal arginine in the rodent post ischemic small bowel. Am. J. Physiol. Gastrointest. Liver Physiol. doi:10.1152/ajpgi.00248.2005.
-
(2005)
Am. J. Physiol. Gastrointest. Liver Physiol.
-
-
Sato, N.1
-
37
-
-
0036924258
-
A specific peroxisome proliferator-activated receptor-gamma (PPAR-gamma) ligand, pioglitazone, ameliorates gastric mucosal damage induced by ischemia and reperfusion in rats
-
Ichikawa, H., et al. 2002. A specific peroxisome proliferator-activated receptor-gamma (PPAR-gamma) ligand, pioglitazone, ameliorates gastric mucosal damage induced by ischemia and reperfusion in rats. Redox Rep. 7:343-346.
-
(2002)
Redox Rep.
, vol.7
, pp. 343-346
-
-
Ichikawa, H.1
-
38
-
-
0038627501
-
Pioglitazone, a specific ligand of the peroxisome proliferator-activated receptor gamma reduces gastric mucosal injury induced by ischaemia/reperfusion in rat
-
Konturek, P.C., et al. 2003. Pioglitazone, a specific ligand of the peroxisome proliferator-activated receptor gamma reduces gastric mucosal injury induced by ischaemia/reperfusion in rat. Scand. J. Gastroenterol. 38:468-476.
-
(2003)
Scand. J. Gastroenterol.
, vol.38
, pp. 468-476
-
-
Konturek, P.C.1
-
39
-
-
18544412176
-
Protective effect of endogenous PPARgamma against acute gastric mucosal lesions associated with ischemia-reperfusion
-
Wada, K., et al. 2004. Protective effect of endogenous PPARgamma against acute gastric mucosal lesions associated with ischemia-reperfusion. Am. J. Physiol. Gastrointest. Liver Physiol. 287:G452-G458.
-
(2004)
Am. J. Physiol. Gastrointest. Liver Physiol.
, vol.287
-
-
Wada, K.1
-
40
-
-
8844239169
-
Rosiglitazone, an agonist of peroxisome proliferator-activated receptor gamma, protects against gastric ischemia-reperfusion damage in rats: Role of oxygen free radicals generation
-
Villegas, I., Martin, A.R., Toma, W., and de la Lastra, C.A. 2004. Rosiglitazone, an agonist of peroxisome proliferator-activated receptor gamma, protects against gastric ischemia-reperfusion damage in rats: role of oxygen free radicals generation. Eur. J. Pharmacol. 505:195-203.
-
(2004)
Eur. J. Pharmacol.
, vol.505
, pp. 195-203
-
-
Villegas, I.1
Martin, A.R.2
Toma, W.3
De La Lastra, C.A.4
-
41
-
-
24644488751
-
The role and regulation of hepatic stellate cell apoptosis in reversal of liver fibrosis
-
Elsharkawy, A.M., Oakley, F., and Mann, D.A. 2005. The role and regulation of hepatic stellate cell apoptosis in reversal of liver fibrosis. Apoptosis. 10:927-939.
-
(2005)
Apoptosis
, vol.10
, pp. 927-939
-
-
Elsharkawy, A.M.1
Oakley, F.2
Mann, D.A.3
-
42
-
-
0038455747
-
Cirrhosis: New research provides a basis for rational and targeted treatments
-
Iredale, J.P. 2003. Cirrhosis: new research provides a basis for rational and targeted treatments. BMJ. 327:143-147.
-
(2003)
BMJ
, vol.327
, pp. 143-147
-
-
Iredale, J.P.1
-
43
-
-
0037663778
-
Activation of peroxisome proliferator-activated receptor-gamma contributes to the inhibitory effects of curcumin on rat hepatic stellate cell growth
-
Xu, J., Fu, Y., and Chen, A. 2003. Activation of peroxisome proliferator-activated receptor-gamma contributes to the inhibitory effects of curcumin on rat hepatic stellate cell growth. Am. J. Physiol. Gastrointest. Liver Physiol. 285:G20-G30.
-
(2003)
Am. J. Physiol. Gastrointest. Liver Physiol.
, vol.285
-
-
Xu, J.1
Fu, Y.2
Chen, A.3
-
44
-
-
0034680787
-
Peroxisome proliferator-activated receptors and hepatic stellate cell activation
-
Miyahara, T., et al. 2000. Peroxisome proliferator-activated receptors and hepatic stellate cell activation. J. Biol. Chem. 275:35715-35722.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 35715-35722
-
-
Miyahara, T.1
-
45
-
-
0033855572
-
Ligands of peroxisome proliferator-activated receptor gamma modulate profibrogenic and proinflammatory actions in hepatic stellate cells
-
Marra, F., et al. 2000. Ligands of peroxisome proliferator-activated receptor gamma modulate profibrogenic and proinflammatory actions in hepatic stellate cells. Gastroenterology. 119:466-478.
-
(2000)
Gastroenterology
, vol.119
, pp. 466-478
-
-
Marra, F.1
-
46
-
-
0036082703
-
Antidiabetic thiazolidinediones inhibit collagen synthesis and hepatic stellate cell activation in vivo and in vitro
-
Galli, A., et al. 2002. Antidiabetic thiazolidinediones inhibit collagen synthesis and hepatic stellate cell activation in vivo and in vitro. Gastroenterology. 122:1924-1940.
-
(2002)
Gastroenterology
, vol.122
, pp. 1924-1940
-
-
Galli, A.1
-
47
-
-
1642524221
-
Peroxisome proliferator-activated receptor gamma induces a phenotypic switch from activated to quiescent hepatic stellate cells
-
Hazra, S., et al. 2004. Peroxisome proliferator-activated receptor gamma induces a phenotypic switch from activated to quiescent hepatic stellate cells. J. Biol. Chem. 279:11392-11401.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 11392-11401
-
-
Hazra, S.1
-
48
-
-
28844502262
-
Peroxisome proliferator-activated receptor gamma suppresses proximal alpha 1(I) collagen promoter via inhibition of p300-facilitated NF-I binding to DNA in hepatic stellate cells
-
Yavrom, S., et al. 2005. Peroxisome proliferator-activated receptor gamma suppresses proximal alpha 1(I) collagen promoter via inhibition of p300-facilitated NF-I binding to DNA in hepatic stellate cells. J. Biol. Chem. 280:40650-40659.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 40650-40659
-
-
Yavrom, S.1
-
49
-
-
14244257340
-
Adipogenic transcriptional regulation of hepatic stellate cells
-
She, H., Xiong, S., Hazra, S., and Tsukamoto, H. 2005. Adipogenic transcriptional regulation of hepatic stellate cells. J. Biol. Chem. 280:4959-4967.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 4959-4967
-
-
She, H.1
Xiong, S.2
Hazra, S.3
Tsukamoto, H.4
-
50
-
-
21744459082
-
The selective cyclooxygenase-2 inhibitor SC-236 reduces liver fibrosis by mechanisms involving non-parenchymal cell apoptosis and PPARgamma activation
-
Planaguma, A., et al. 2005. The selective cyclooxygenase-2 inhibitor SC-236 reduces liver fibrosis by mechanisms involving non-parenchymal cell apoptosis and PPARgamma activation. FASEB J. 19:1120-1122.
-
(2005)
FASEB J.
, vol.19
, pp. 1120-1122
-
-
Planaguma, A.1
-
51
-
-
25644443217
-
Cross-talk between farnesoid-X-receptor (FXR) and peroxisome proliferator-activated receptor gamma contributes to the antifibrotic activity of FXR ligands in rodent models of liver cirrhosis
-
Fiorucci, S., et al. 2005. Cross-talk between farnesoid-X-receptor (FXR) and peroxisome proliferator-activated receptor gamma contributes to the antifibrotic activity of FXR ligands in rodent models of liver cirrhosis. J. Pharmacol. Exp. Ther. 315:58-68.
-
(2005)
J. Pharmacol. Exp. Ther.
, vol.315
, pp. 58-68
-
-
Fiorucci, S.1
-
52
-
-
24144496168
-
Thiazolidinedione treatment inhibits bile duct proliferation and fibrosis in a rat model of chronic cholestasis
-
Marra, F., et al. 2005. Thiazolidinedione treatment inhibits bile duct proliferation and fibrosis in a rat model of chronic cholestasis. World J. Gastroenterol. 11:4931-4938.
-
(2005)
World J. Gastroenterol.
, vol.11
, pp. 4931-4938
-
-
Marra, F.1
-
53
-
-
0037221210
-
Peroxisome proliferator-activated receptor-beta signaling contributes to enhanced proliferation of hepatic stellate cells
-
Hellemans, K., et al. 2003. Peroxisome proliferator-activated receptor-beta signaling contributes to enhanced proliferation of hepatic stellate cells. Gastroenterology. 124:184-201.
-
(2003)
Gastroenterology
, vol.124
, pp. 184-201
-
-
Hellemans, K.1
-
54
-
-
5144224821
-
PPARalpha ligands activate antioxidant enzymes and suppress hepatic fibrosis in rats
-
Toyama, T., et al. 2004. PPARalpha ligands activate antioxidant enzymes and suppress hepatic fibrosis in rats. Biochem. Biophys. Res. Commun. 324:697-704.
-
(2004)
Biochem. Biophys. Res. Commun.
, vol.324
, pp. 697-704
-
-
Toyama, T.1
-
55
-
-
1642347937
-
Peroxisome proliferator-activated receptor-alpha regulates postischemic liver injury
-
Okaya, T., and Lentsch, A.B. 2004. Peroxisome proliferator-activated receptor-alpha regulates postischemic liver injury. Am. J. Physiol. Gastrointest. Liver Physiol. 286:G606-G612.
-
(2004)
Am. J. Physiol. Gastrointest. Liver Physiol.
, vol.286
-
-
Okaya, T.1
Lentsch, A.B.2
-
56
-
-
0036120125
-
Hepatic regeneration in peroxisome proliferator-activated receptor alpha-null mice after partial hepatectomy
-
Rao, M.S., Peters, J.M., Gonzalez, F.J., and Reddy, J.K. 2002. Hepatic regeneration in peroxisome proliferator-activated receptor alpha-null mice after partial hepatectomy. Hepatol. Res. 22:52-57.
-
(2002)
Hepatol. Res.
, vol.22
, pp. 52-57
-
-
Rao, M.S.1
Peters, J.M.2
Gonzalez, F.J.3
Reddy, J.K.4
-
57
-
-
0037305697
-
Impaired Ras membrane association and activation in PPARalpha knockout mice after partial hepatectomy
-
Wheeler, M.D., et al. 2003. Impaired Ras membrane association and activation in PPARalpha knockout mice after partial hepatectomy. Am. J. Physiol. Gastrointest. Liver Physiol. 284:G302-G312.
-
(2003)
Am. J. Physiol. Gastrointest. Liver Physiol.
, vol.284
-
-
Wheeler, M.D.1
-
58
-
-
0036730442
-
Delayed liver regeneration in peroxisome proliferator-activated receptor-alpha-null mice
-
Anderson, S.P., et al. 2002. Delayed liver regeneration in peroxisome proliferator-activated receptor-alpha-null mice. Hepatology. 36:544-554.
-
(2002)
Hepatology
, vol.36
, pp. 544-554
-
-
Anderson, S.P.1
-
59
-
-
14544276802
-
Decreased expression of peroxisome proliferator-activated receptor alpha and liver fatty acid binding protein after partial hepatectomy of rats and mice
-
Skrtic, S., et al. 2005. Decreased expression of peroxisome proliferator-activated receptor alpha and liver fatty acid binding protein after partial hepatectomy of rats and mice. Liver Int. 25:33-40.
-
(2005)
Liver Int.
, vol.25
, pp. 33-40
-
-
Skrtic, S.1
-
60
-
-
0029550455
-
Prophylactic pharmacologic neuroprotection against focal cerebral ischemia
-
Jonas, S. 1995. Prophylactic pharmacologic neuroprotection against focal cerebral ischemia. Ann. N. Y. Acad. Sci. 765:21-25; discussion 26-27.
-
(1995)
Ann. N. Y. Acad. Sci.
, vol.765
, pp. 21-25
-
-
Jonas, S.1
-
61
-
-
0035849546
-
Reduction in stroke with gemfibrozil in men with coronary heart disease and low HDL cholesterol: The Veterans Affairs HDL Intervention Trial (VA-HIT)
-
Bloomfield Rubins, H., et al. 2001. Reduction in stroke with gemfibrozil in men with coronary heart disease and low HDL cholesterol: The Veterans Affairs HDL Intervention Trial (VA-HIT). Circulation. 103:2828-2833.
-
(2001)
Circulation
, vol.103
, pp. 2828-2833
-
-
Bloomfield Rubins, H.1
-
62
-
-
0038720453
-
Peroxisome proliferator-activated receptor-alpha activation as a mechanism of preventive neuroprotection induced by chronic fenofibrate treatment
-
Deplanque, D., et al. 2003. Peroxisome proliferator-activated receptor-alpha activation as a mechanism of preventive neuroprotection induced by chronic fenofibrate treatment. J. Neurosci. 23:6264-6271.
-
(2003)
J. Neurosci.
, vol.23
, pp. 6264-6271
-
-
Deplanque, D.1
-
63
-
-
1642268085
-
Brain protection by resveratrol and fenofibrate against stroke requires peroxisome proliferator-activated receptor alpha in mice
-
Inoue, H., et al. 2003. Brain protection by resveratrol and fenofibrate against stroke requires peroxisome proliferator-activated receptor alpha in mice. Neurosci. Lett. 352:203-206.
-
(2003)
Neurosci. Lett.
, vol.352
, pp. 203-206
-
-
Inoue, H.1
-
64
-
-
28844467909
-
Peroxisomal proliferation protects from beta-amyloid neurodegeneration
-
Santos, M.J., et al. 2005. Peroxisomal proliferation protects from beta-amyloid neurodegeneration. J. Biol. Chem. 280:41057-41068.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 41057-41068
-
-
Santos, M.J.1
-
65
-
-
12844281747
-
A peroxisome proliferator-activated receptor-gamma agonist reduces infarct size in transient but not in permanent ischemia
-
Shimazu, T., et al. 2005. A peroxisome proliferator-activated receptor-gamma agonist reduces infarct size in transient but not in permanent ischemia. Stroke. 36:353-359.
-
(2005)
Stroke
, vol.36
, pp. 353-359
-
-
Shimazu, T.1
-
66
-
-
10044289268
-
Peroxisome proliferator-activated receptor-gamma ligands reduce inflammation and infarction size in transient focal ischemia
-
Sundararajan, S., et al. 2005. Peroxisome proliferator-activated receptor-gamma ligands reduce inflammation and infarction size in transient focal ischemia. Neuroscience. 130:685-696.
-
(2005)
Neuroscience
, vol.130
, pp. 685-696
-
-
Sundararajan, S.1
-
67
-
-
23044475502
-
The intracerebral application of the PPARgamma-ligand pioglitazone confers neuroprotection against focal ischaemia in the rat brain
-
Zhao, Y., Patzer, A., Gohlke, P., Herdegen, T., and Culman, J. 2005. The intracerebral application of the PPARgamma-ligand pioglitazone confers neuroprotection against focal ischaemia in the rat brain. Eur J. Neurosci. 22:278-282.
-
(2005)
Eur J. Neurosci.
, vol.22
, pp. 278-282
-
-
Zhao, Y.1
Patzer, A.2
Gohlke, P.3
Herdegen, T.4
Culman, J.5
-
68
-
-
0037311051
-
Effects of peroxisome proliferator-activated receptor-gamma agonists on central nervous system inflammation
-
Kielian, T., and Drew, P.D. 2003. Effects of peroxisome proliferator-activated receptor-gamma agonists on central nervous system inflammation. J. Neurosci. Res. 71:315-325.
-
(2003)
J. Neurosci. Res.
, vol.71
, pp. 315-325
-
-
Kielian, T.1
Drew, P.D.2
-
69
-
-
23944490153
-
The oral antidiabetic pioglitazone protects from neurodegeneration and amyotrophic lateral sclerosis-like symptoms in superoxide dismutase-G93A transgenic mice
-
Schutz, B., et al. 2005. The oral antidiabetic pioglitazone protects from neurodegeneration and amyotrophic lateral sclerosis-like symptoms in superoxide dismutase-G93A transgenic mice. J. Neurosci. 25:7805-7812.
-
(2005)
J. Neurosci.
, vol.25
, pp. 7805-7812
-
-
Schutz, B.1
-
70
-
-
0034467428
-
PPAR signaling in the control of cardiac energy metabolism
-
Barger, P.M., and Kelly, D.P. 2000. PPAR signaling in the control of cardiac energy metabolism. Trends Cardiovasc. Med. 10:238-245.
-
(2000)
Trends Cardiovasc. Med.
, vol.10
, pp. 238-245
-
-
Barger, P.M.1
Kelly, D.P.2
-
71
-
-
1542496389
-
Short- and long-term beneficial effects of trimetazidine in patients with diabetes and ischemic cardiomyopathy
-
Fragasso, G., et al. 2003. Short- and long-term beneficial effects of trimetazidine in patients with diabetes and ischemic cardiomyopathy. Am. Heart J. 146:E18.
-
(2003)
Am. Heart J.
, vol.146
-
-
Fragasso, G.1
-
72
-
-
33644662725
-
Chronic activation of PPARalpha is detrimental to cardiac recovery following ischemia
-
Sambandam, N., et al. 2006. Chronic activation of PPARalpha is detrimental to cardiac recovery following ischemia. Am. J. Physiol. Heart Circ. Physiol. 290:H87-H95.
-
(2006)
Am. J. Physiol. Heart Circ. Physiol.
, vol.290
-
-
Sambandam, N.1
-
73
-
-
0034678082
-
The antianginal drug trimetazidine shifts cardiac energy metabolism from fatty acid oxidation to glucose oxidation by inhibiting mitochondrial long-chain 3-ketoacyl coenzyme A thiolase
-
Kantor, P.F., Lucien, A., Kozak, R., and Lopaschuk, G.D. 2000. The antianginal drug trimetazidine shifts cardiac energy metabolism from fatty acid oxidation to glucose oxidation by inhibiting mitochondrial long-chain 3-ketoacyl coenzyme A thiolase. Circ. Res. 86:580-588.
-
(2000)
Circ. Res.
, vol.86
, pp. 580-588
-
-
Kantor, P.F.1
Lucien, A.2
Kozak, R.3
Lopaschuk, G.D.4
-
74
-
-
0037151101
-
Transcriptional effects of chronic Akt activation in the heart
-
Cook, S.A., Matsui, T., Li, L., and Rosenzweig, A. 2002. Transcriptional effects of chronic Akt activation in the heart. J. Biol. Chem. 277:22528-22533.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 22528-22533
-
-
Cook, S.A.1
Matsui, T.2
Li, L.3
Rosenzweig, A.4
-
75
-
-
0242525729
-
Activation of peroxisome proliferator-activated receptor-alpha protects the heart from ischemia/reperfusion injury
-
Yue, T.L., et al. 2003. Activation of peroxisome proliferator-activated receptor-alpha protects the heart from ischemia/reperfusion injury. Circulation. 108:2393-2399.
-
(2003)
Circulation
, vol.108
, pp. 2393-2399
-
-
Yue, T.L.1
-
76
-
-
0036314839
-
Ligands of the peroxisome proliferator-activated receptors (PPARgamma and PPAR-alpha) reduce myocardial infarct size
-
Wayman, N.S., et al. 2002. Ligands of the peroxisome proliferator- activated receptors (PPARgamma and PPAR-alpha) reduce myocardial infarct size. FASEB J. 16:1027-1040.
-
(2002)
FASEB J.
, vol.16
, pp. 1027-1040
-
-
Wayman, N.S.1
-
77
-
-
2642581745
-
Activation of the peroxisome proliferator-activated receptor alpha protects against myocardial ischaemic injury and improves endothelial vasodilatation
-
Tabernero, A., et al. 2002. Activation of the peroxisome proliferator-activated receptor alpha protects against myocardial ischaemic injury and improves endothelial vasodilatation. BMC Pharmacol. 2:10.
-
(2002)
BMC Pharmacol.
, vol.2
, pp. 10
-
-
Tabernero, A.1
-
78
-
-
0141788713
-
Troglitazone administration limits infarct size by reduced phosphorylation of canine myocardial connexin43 proteins
-
Lee, T.M., and Chou, T.F. 2003. Troglitazone administration limits infarct size by reduced phosphorylation of canine myocardial connexin43 proteins. Am. J. Physiol. Heart Circ. Physiol. 285:H1650-H1659.
-
(2003)
Am. J. Physiol. Heart Circ. Physiol.
, vol.285
-
-
Lee, T.M.1
Chou, T.F.2
-
79
-
-
0037058874
-
Pioglitazone, a peroxisome proliferator-activated receptor-gamma agonist, attenuates left ventricular remodeling and failure after experimental myocardial infarction
-
Shiomi, T., et al. 2002. Pioglitazone, a peroxisome proliferator- activated receptor-gamma agonist, attenuates left ventricular remodeling and failure after experimental myocardial infarction. Circulation. 106:3126-3132.
-
(2002)
Circulation
, vol.106
, pp. 3126-3132
-
-
Shiomi, T.1
-
80
-
-
0035923566
-
In vivo myocardial protection from ischemia/reperfusion injury by the peroxisome proliferator-activated receptor-gamma agonist rosiglitazone
-
Yue, T.-L., et al. 2001. In vivo myocardial protection from ischemia/reperfusion injury by the peroxisome proliferator-activated receptor-gamma agonist rosiglitazone. Circulation. 104:2588-2594.
-
(2001)
Circulation
, vol.104
, pp. 2588-2594
-
-
Yue, T.-L.1
-
81
-
-
0036319490
-
Rosiglitazone, a peroxisome proliferator-activated receptor-gamma, inhibits the Jun NH(2)-terminal kinase/activating protein 1 pathway and protects the heart from ischemia/reperfusion injury
-
Khandoudi, N., et al. 2002. Rosiglitazone, a peroxisome proliferator-activated receptor-gamma, inhibits the Jun NH(2)-terminal kinase/activating protein 1 pathway and protects the heart from ischemia/reperfusion injury. Diabetes. 51:1507-1514.
-
(2002)
Diabetes
, vol.51
, pp. 1507-1514
-
-
Khandoudi, N.1
-
82
-
-
0036224012
-
Thiazolidinedione treatment normalizes insulin resistance and ischemic injury in the zucker fatty rat heart
-
Sidell, R.J., et al. 2002. Thiazolidinedione treatment normalizes insulin resistance and ischemic injury in the zucker fatty rat heart. Diabetes. 51:1110-1117.
-
(2002)
Diabetes
, vol.51
, pp. 1110-1117
-
-
Sidell, R.J.1
-
83
-
-
1542268988
-
Anti-apoptotic effects of rosiglitazone in hypercholesterolemic rabbits subjected to myocardial ischemia and reperfusion
-
Liu, H.R., et al. 2004. Anti-apoptotic effects of rosiglitazone in hypercholesterolemic rabbits subjected to myocardial ischemia and reperfusion. Cardiovasc. Res. 62:135-144.
-
(2004)
Cardiovasc. Res.
, vol.62
, pp. 135-144
-
-
Liu, H.R.1
-
84
-
-
26244453309
-
Secondary prevention of macrovascular events in patients with type 2 diabetes in the PROactive Study (PROspective pioglitAzone Clinical Trial in macroVascular Events): A randomised controlled trial
-
Dormandy, J.A., et al. 2005. Secondary prevention of macrovascular events in patients with type 2 diabetes in the PROactive Study (PROspective pioglitAzone Clinical Trial In macroVascular Events): a randomised controlled trial. Lancet. 366:1279-1289.
-
(2005)
Lancet
, vol.366
, pp. 1279-1289
-
-
Dormandy, J.A.1
-
85
-
-
0242332284
-
Use of thiazolidinediones and risk of heart failure in people with type 2 diabetes: A retrospective cohort study
-
Delea, T.E., Edelsberg, J.S., Hagiwara, M., Oster, G., and Phillips, L.S. 2003. Use of thiazolidinediones and risk of heart failure in people with type 2 diabetes: a retrospective cohort study. Diabetes Care. 26:2983-2989.
-
(2003)
Diabetes Care
, vol.26
, pp. 2983-2989
-
-
Delea, T.E.1
Edelsberg, J.S.2
Hagiwara, M.3
Oster, G.4
Phillips, L.S.5
-
86
-
-
0038460061
-
The PPARgamma-activator rosiglitazone does not alter remodeling but increases mortality in rats post-myocardial infarction
-
Lygate, C.A., et al. 2003. The PPARgamma-activator rosiglitazone does not alter remodeling but increases mortality in rats post-myocardial infarction. Cardiovasc. Res. 58:632-637.
-
(2003)
Cardiovasc. Res.
, vol.58
, pp. 632-637
-
-
Lygate, C.A.1
-
87
-
-
0242516069
-
Deleterious effects of acute treatment with a peroxisome proliferator-activated receptor-gamma activator in myocardial ischemia and reperfusion in pigs
-
Xu, Y., et al. 2003. Deleterious effects of acute treatment with a peroxisome proliferator-activated receptor-gamma activator in myocardial ischemia and reperfusion in pigs. Diabetes. 52:1187-1194.
-
(2003)
Diabetes
, vol.52
, pp. 1187-1194
-
-
Xu, Y.1
-
88
-
-
0141928168
-
Peroxisome proliferator-activated receptor-alpha and receptor-gamma activators prevent cardiac fibrosis in mineralocorticoid-dependent hypertension
-
Iglarz, M., et al. 2003. Peroxisome proliferator-activated receptor-alpha and receptor-gamma activators prevent cardiac fibrosis in mineralocorticoid- dependent hypertension. Hypertension. 42:737-743.
-
(2003)
Hypertension
, vol.42
, pp. 737-743
-
-
Iglarz, M.1
-
89
-
-
1942484870
-
Myocardial fibrosis and diastolic dysfunction in deoxycorticosterone acetate-salt hypertensive rats is ameliorated by the peroxisome proliferator-activated receptor-alpha activator fenofibrate, partly by suppressing inflammatory responses associated with the nuclear factor-kappa-B pathway
-
Ogata, T., et al. 2004. Myocardial fibrosis and diastolic dysfunction in deoxycorticosterone acetate-salt hypertensive rats is ameliorated by the peroxisome proliferator-activated receptor-alpha activator fenofibrate, partly by suppressing inflammatory responses associated with the nuclear factor-kappa-B pathway. J. Am. Coll. Cardiol. 43:1481-1488.
-
(2004)
J. Am. Coll. Cardiol.
, vol.43
, pp. 1481-1488
-
-
Ogata, T.1
-
90
-
-
1042286369
-
PPAR alpha activator fenofibrate inhibits myocardial inflammation and fibrosis in angiotensin II-infused rats
-
Diep, Q.N., et al. 2004. PPAR alpha activator fenofibrate inhibits myocardial inflammation and fibrosis in angiotensin II-infused rats. J. Mol. Cell. Cardiol. 36:295-304.
-
(2004)
J. Mol. Cell. Cardiol.
, vol.36
, pp. 295-304
-
-
Diep, Q.N.1
-
91
-
-
9744247507
-
Anoxia-reoxygenation stimulates collagen type-I and MMP-1 expression in cardiac fibroblasts: Modulation by the PPAR-gamma ligand pioglitazone
-
Chen, K., Li, D., Zhang, X., Hermonat, P.L., and Mehta, J.L. 2004. Anoxia-reoxygenation stimulates collagen type-I and MMP-1 expression in cardiac fibroblasts: modulation by the PPAR-gamma ligand pioglitazone. J. Cardiovasc. Pharmacol. 44:682-687.
-
(2004)
J. Cardiovasc. Pharmacol.
, vol.44
, pp. 682-687
-
-
Chen, K.1
Li, D.2
Zhang, X.3
Hermonat, P.L.4
Mehta, J.L.5
-
92
-
-
1942468955
-
Peroxisome proliferator activator receptors (PPAR), insulin resistance, and cardiomyopathy: Friends or foes for the diabetic patient with heart failure?
-
Nikolaidis, L.A., and Levine, T.B. 2004. Peroxisome proliferator activator receptors (PPAR), insulin resistance, and cardiomyopathy: friends or foes for the diabetic patient with heart failure? Cardiol. Rev. 12:158-170.
-
(2004)
Cardiol. Rev.
, vol.12
, pp. 158-170
-
-
Nikolaidis, L.A.1
Levine, T.B.2
-
93
-
-
33644645475
-
Commentary on the results and clinical implications of the PROactive study
-
Rizza, R., Henry, R., and Kahn, R. 2005. Commentary on the results and clinical implications of the PROactive study. Diabetes Care. 28:2965-2967.
-
(2005)
Diabetes Care
, vol.28
, pp. 2965-2967
-
-
Rizza, R.1
Henry, R.2
Kahn, R.3
-
94
-
-
0032133776
-
Systemic inflammatory response syndrome (SIRS), multiple organ dysfunction syndrome (MODS), multiple organ failure (MOF): Are we winning the battle?
-
Baue, A.E., Durham, R., and Faist, E. 1998. Systemic inflammatory response syndrome (SIRS), multiple organ dysfunction syndrome (MODS), multiple organ failure (MOF): are we winning the battle? Shock. 10:79-89.
-
(1998)
Shock
, vol.10
, pp. 79-89
-
-
Baue, A.E.1
Durham, R.2
Faist, E.3
-
95
-
-
13844297687
-
Beneficial effects of PPAR-gamma ligands in ischemia-reperfusion injury, inflammation and shock
-
Abdelrahman, M., Sivarajah, A., and Thiemermann, C. 2005. Beneficial effects of PPAR-gamma ligands in ischemia-reperfusion injury, inflammation and shock. Cardiovasc. Res. 65:772-781.
-
(2005)
Cardiovasc. Res.
, vol.65
, pp. 772-781
-
-
Abdelrahman, M.1
Sivarajah, A.2
Thiemermann, C.3
-
96
-
-
17644405062
-
Peroxisome proliferator-activated receptor-gamma is a new therapeutic target in sepsis and inflammation
-
Zingarelli, B., and Cook, J.A. 2005. Peroxisome proliferator-activated receptor-gamma is a new therapeutic target in sepsis and inflammation. Shock. 23:393-399.
-
(2005)
Shock
, vol.23
, pp. 393-399
-
-
Zingarelli, B.1
Cook, J.A.2
-
97
-
-
21744458404
-
15-Deoxy-Delta(12,14)-prostaglandin J(2) (15D-PGJ(2)), a peroxisome proliferator activated receptor gamma ligand, reduces tissue leukosequestration and mortality in endotoxic shock
-
Kaplan, J.M., et al. 2005. 15-Deoxy-Delta(12,14)-prostaglandin J(2) (15D-PGJ(2)), a peroxisome proliferator activated receptor gamma ligand, reduces tissue leukosequestration and mortality in endotoxic shock. Shock. 24:59-65.
-
(2005)
Shock
, vol.24
, pp. 59-65
-
-
Kaplan, J.M.1
-
98
-
-
25144496538
-
Pretreatment with peroxysome proliferator-activated receptor alpha agonist fenofibrate protects endothelium in rabbit Escherichia coli endotoxin-induced shock
-
Wiel, E., et al. 2005. Pretreatment with peroxysome proliferator- activated receptor alpha agonist fenofibrate protects endothelium in rabbit Escherichia coli endotoxin-induced shock. Intensive Care Med. 31:1269-1279.
-
(2005)
Intensive Care Med.
, vol.31
, pp. 1269-1279
-
-
Wiel, E.1
-
99
-
-
9644275533
-
The peroxisome proliferator-activated receptor-gamma ligand 15-deoxyDelta12,14 prostaglandin J2 reduces the organ injury in hemorrhagic shock
-
Abdelrahman, M., Collin, M., and Thiemermann, C. 2004. The peroxisome proliferator-activated receptor-gamma ligand 15-deoxyDelta12,14 prostaglandin J2 reduces the organ injury in hemorrhagic shock. Shock. 22:555-561.
-
(2004)
Shock
, vol.22
, pp. 555-561
-
-
Abdelrahman, M.1
Collin, M.2
Thiemermann, C.3
-
100
-
-
33644640503
-
Preclinical models of shock and sepsis: What can they tell us?
-
Marshall, J.C., et al. 2005. Preclinical models of shock and sepsis: what can they tell us? Shock. 24(Suppl. 1):1-6.
-
(2005)
Shock
, vol.24
, Issue.1 SUPPL.
, pp. 1-6
-
-
Marshall, J.C.1
-
101
-
-
20144386127
-
Robustness, scalability, and integration of a wound-response gene expression signature in predicting breast cancer survival
-
Chang, H.Y., et al. 2005. Robustness, scalability, and integration of a wound-response gene expression signature in predicting breast cancer survival. Proc. Natl. Acad. Sci. U. S. A. 102:3738-3743.
-
(2005)
Proc. Natl. Acad. Sci. U. S. A.
, vol.102
, pp. 3738-3743
-
-
Chang, H.Y.1
-
102
-
-
0347753697
-
Peroxisome-proliferator-activated receptors and cancers: Complex stories
-
Michalik, L., Desvergne, B., and Wahli, W. 2004. Peroxisome-proliferator- activated receptors and cancers: complex stories. Nat. Rev. Cancer. 4:61-70.
-
(2004)
Nat. Rev. Cancer
, vol.4
, pp. 61-70
-
-
Michalik, L.1
Desvergne, B.2
Wahli, W.3
-
103
-
-
1942471942
-
Peroxisome proliferator activated receptor-gamma (PPAR-gamma) ligands and angiogenesis
-
Margeli, A., Kouraklis, G., and Theocharis, S. 2003. Peroxisome proliferator activated receptor-gamma (PPAR-gamma) ligands and angiogenesis. Angiogenesis. 6:165-169.
-
(2003)
Angiogenesis
, vol.6
, pp. 165-169
-
-
Margeli, A.1
Kouraklis, G.2
Theocharis, S.3
-
104
-
-
15744396059
-
PPAR-gamma activation inhibits angiogenesis by blocking ELR+CXC chemokine production in non-small cell lung cancer
-
Keshamouni, V.G., et al. 2005. PPAR-gamma activation inhibits angiogenesis by blocking ELR+CXC chemokine production in non-small cell lung cancer. Neoplasia. 7:294-301.
-
(2005)
Neoplasia
, vol.7
, pp. 294-301
-
-
Keshamouni, V.G.1
-
105
-
-
13844294425
-
Inhibition of corneal neovascularization by a peroxisome proliferator-activated receptor-gamma ligand
-
Sarayba, M.A., et al. 2005. Inhibition of corneal neovascularization by a peroxisome proliferator-activated receptor-gamma ligand. Exp. Eye Res. 80:435-442.
-
(2005)
Exp. Eye Res.
, vol.80
, pp. 435-442
-
-
Sarayba, M.A.1
-
106
-
-
0036771776
-
PPARγ ligands inhibit primary tumor growth and metastasis by inhibiting angiogenesis
-
doi:10.1172/JCI200215634
-
Panigrahy, D., et al. 2002. PPARγ ligands inhibit primary tumor growth and metastasis by inhibiting angiogenesis. J. Clin. Invest. 110:923-932. doi:10.1172/JCI200215634.
-
(2002)
J. Clin. Invest.
, vol.110
, pp. 923-932
-
-
Panigrahy, D.1
-
107
-
-
2142701648
-
Peroxisome proliferator-activated receptor-gamma ligands inhibit choroidal neovascularization
-
Murata, T., et al. 2000. Peroxisome proliferator-activated receptor-gamma ligands inhibit choroidal neovascularization. Invest. Ophthalmol. Vis. Sci. 41:2309-2317.
-
(2000)
Invest. Ophthalmol. Vis. Sci.
, vol.41
, pp. 2309-2317
-
-
Murata, T.1
-
108
-
-
0033605677
-
Peroxisome proliferator-activated receptor gamma ligands are potent inhibitors of angiogenesis in vitro and in vivo
-
Xin, X., Yang, S., Kowalski, J., and Gerritsen, M.E. 1999. Peroxisome proliferator-activated receptor gamma ligands are potent inhibitors of angiogenesis in vitro and in vivo. J. Biol. Chem. 274:9116-9121.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 9116-9121
-
-
Xin, X.1
Yang, S.2
Kowalski, J.3
Gerritsen, M.E.4
-
109
-
-
0036840309
-
Leptin induces endothelial cell migration through Akt, which is inhibited by PPARgamma-ligands
-
Goetze, S., et al. 2002. Leptin induces endothelial cell migration through Akt, which is inhibited by PPARgamma-ligands. Hypertension. 40:748-754.
-
(2002)
Hypertension
, vol.40
, pp. 748-754
-
-
Goetze, S.1
-
110
-
-
0033547443
-
Regulation of gene expression by activation of the peroxisome proliferator-activated receptor gamma with rosiglitazone (BRL 49653) in human adipocytes
-
Rieusset, J., Auwerx, J., and Vidal, H. 1999. Regulation of gene expression by activation of the peroxisome proliferator-activated receptor gamma with rosiglitazone (BRL 49653) in human adipocytes. Biochem. Biophys. Res. Commun. 265:265-271.
-
(1999)
Biochem. Biophys. Res. Commun.
, vol.265
, pp. 265-271
-
-
Rieusset, J.1
Auwerx, J.2
Vidal, H.3
-
111
-
-
0034666157
-
Characterization of the fasting-induced adipose factor FIAF, a novel peroxisome proliferator-activated receptor target gene
-
Kersten, S., et al. 2000. Characterization of the fasting-induced adipose factor FIAF, a novel peroxisome proliferator-activated receptor target gene. J. Biol. Chem. 275:28488-28493.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 28488-28493
-
-
Kersten, S.1
-
112
-
-
0343060983
-
Peroxisome proliferator-activated receptor gamma target gene encoding a novel angiopoietin-related protein associated with adipose differentiation
-
Yoon, J.C., et al. 2000. Peroxisome proliferator-activated receptor gamma target gene encoding a novel angiopoietin-related protein associated with adipose differentiation. Mol. Cell. Biol. 20:5343-5349.
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 5343-5349
-
-
Yoon, J.C.1
-
113
-
-
0036660804
-
Hypoxia up-regulates expression of peroxisome proliferator-activated receptor gamma angiopoietin-related gene (PGAR) in cardiomyocytes: Role of hypoxia inducible factor 1alpha
-
Belanger, A.J., et al. 2002. Hypoxia up-regulates expression of peroxisome proliferator-activated receptor gamma angiopoietin-related gene (PGAR) in cardiomyocytes: role of hypoxia inducible factor 1alpha. J. Mol. Cell. Cardiol. 34:765-774.
-
(2002)
J. Mol. Cell. Cardiol.
, vol.34
, pp. 765-774
-
-
Belanger, A.J.1
-
114
-
-
0038702371
-
Fenofibrate inhibits angiogenesis in vitro and in vivo
-
Varet, J., et al. 2003. Fenofibrate inhibits angiogenesis in vitro and in vivo. Cell. Mol. Life Sci. 60:810-819.
-
(2003)
Cell. Mol. Life Sci.
, vol.60
, pp. 810-819
-
-
Varet, J.1
-
115
-
-
33748041453
-
Efficacy of peroxisome proliferative activated receptor (PPAR)-alpha ligands, fenofibrate, on intimal hyperplasia and constrictive remodeling after coronary angioplasty in porcine models
-
doi:10.1016/j.atherosclerosis.2005.10.047
-
Kasai, T., Miyauchi, K., Yokoyama, T., Aihara, K., and Daida, H. 2005. Efficacy of peroxisome proliferative activated receptor (PPAR)-alpha ligands, fenofibrate, on intimal hyperplasia and constrictive remodeling after coronary angioplasty in porcine models. Atherosclerosis. doi:10.1016/j.atherosclerosis. 2005.10.047.
-
(2005)
Atherosclerosis
-
-
Kasai, T.1
Miyauchi, K.2
Yokoyama, T.3
Aihara, K.4
Daida, H.5
-
116
-
-
17444371632
-
Peroxisome proliferator-activated receptors in squamous cell carcinoma and its precursors
-
Nijsten, T., Geluyckens, E., Colpaert, C., and Lambert, J. 2005. Peroxisome proliferator-activated receptors in squamous cell carcinoma and its precursors. J. Cutan. Pathol. 32:340-347.
-
(2005)
J. Cutan. Pathol.
, vol.32
, pp. 340-347
-
-
Nijsten, T.1
Geluyckens, E.2
Colpaert, C.3
Lambert, J.4
-
117
-
-
0034779322
-
Correlation of expression of cyclooxygenase-2, vascular endothelial growth factor, and peroxisome proliferator-activated receptor delta with head and neck squamous cell carcinoma
-
Jaeckel, E.C., et al. 2001. Correlation of expression of cyclooxygenase-2, vascular endothelial growth factor, and peroxisome proliferator-activated receptor delta with head and neck squamous cell carcinoma. Arch. Otolaryngol. Head Neck Surg. 127:1253-1259.
-
(2001)
Arch. Otolaryngol. Head Neck Surg.
, vol.127
, pp. 1253-1259
-
-
Jaeckel, E.C.1
-
118
-
-
0037188941
-
Role of Akt signaling in vascular homeostasis and angiogenesis
-
Shiojima, I., and Walsh, K. 2002. Role of Akt signaling in vascular homeostasis and angiogenesis. Circ. Res. 90:1243-1250.
-
(2002)
Circ. Res.
, vol.90
, pp. 1243-1250
-
-
Shiojima, I.1
Walsh, K.2
-
119
-
-
0029661982
-
The PPARalpha-leukotriene B4 pathway to inflammation control
-
Devchand, P.R., et al. 1996. The PPARalpha-leukotriene B4 pathway to inflammation control. Nature. 384:39-43.
-
(1996)
Nature
, vol.384
, pp. 39-43
-
-
Devchand, P.R.1
-
120
-
-
21744453780
-
Epithelial cells and their neighbors. I. Role of intestinal myofibroblasts in development, repair, and cancer
-
Powell, D.W., Adegboyega, P.A., Di Mari, J.F., and Mifflin, R.C. 2005. Epithelial cells and their neighbors. I. Role of intestinal myofibroblasts in development, repair, and cancer. Am. J. Physiol. Gastrointest. Liver Physiol. 289:G2-G7.
-
(2005)
Am. J. Physiol. Gastrointest. Liver Physiol.
, vol.289
-
-
Powell, D.W.1
Adegboyega, P.A.2
Di Mari, J.F.3
Mifflin, R.C.4
-
121
-
-
26444515531
-
Different effects of growth factors on proliferation and matrix production of normal and fibrotic human lung fibroblasts
-
Hetzel, M., Bachem, M., Anders, D., Trischler, G., and Faehling, M. 2005. Different effects of growth factors on proliferation and matrix production of normal and fibrotic human lung fibroblasts. Lung. 183:225-237.
-
(2005)
Lung
, vol.183
, pp. 225-237
-
-
Hetzel, M.1
Bachem, M.2
Anders, D.3
Trischler, G.4
Faehling, M.5
-
122
-
-
85035392112
-
Liver fibrosis
-
doi:10.1172/JCI200524282
-
Bataller, R., and Brenner, D.A. 2005. Liver fibrosis. J. Clin. Invest. 115:209-218. doi:10.1172/JCI200524282.
-
(2005)
J. Clin. Invest.
, vol.115
, pp. 209-218
-
-
Bataller, R.1
Brenner, D.A.2
-
123
-
-
22344456349
-
Insights into the mechanisms of renal fibrosis: Is it possible to achieve regression?
-
Chatziantoniou, C., and Dussaule, J.C. 2005. Insights into the mechanisms of renal fibrosis: is it possible to achieve regression? Am. J. Physiol. Renal Physiol. 289:F227-F234.
-
(2005)
Am. J. Physiol. Renal Physiol.
, vol.289
-
-
Chatziantoniou, C.1
Dussaule, J.C.2
-
124
-
-
33644858190
-
Treating the metabolic syndrome using angiotensin receptor antagonists that selectively modulate peroxisome proliferator-activated receptor-γ
-
doi:10.1016/j.biocel.2005.08.006
-
Pershadsingh, H.A. 2005. Treating the metabolic syndrome using angiotensin receptor antagonists that selectively modulate peroxisome proliferator-activated receptor-γ. Int. J. Biochem. Cell Biol. doi:10.1016/j.biocel.2005.08.006.
-
(2005)
Int. J. Biochem. Cell Biol.
-
-
Pershadsingh, H.A.1
-
125
-
-
27944493875
-
Dosage-dependent effects of Akt1/protein kinase Balpha (PKBalpha) and Akt3/PKBgamma on thymus, skin, and cardiovascular and nervous system development in mice
-
Yang, Z.Z., et al. 2005. Dosage-dependent effects of Akt1/protein kinase Balpha (PKBalpha) and Akt3/PKBgamma on thymus, skin, and cardiovascular and nervous system development in mice. Mol. Cell. Biol. 25:10407-10418.
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 10407-10418
-
-
Yang, Z.Z.1
|