Inhibitors of poly(ADP-ribose) polymerase modulate signal transduction pathways and secondary damage in experimental spinal cord trauma

Journal of Pharmacology and Experimental Therapeutics

Volumn 312, Issue 2, 2005, Pages 449-457

  Genovese, Tiziana ^a   Mazzon, Emanuela ^a   Muià, Carmelo ^a   Patel, Nimesh S A ^b   Threadgill, Michael D ^c   Bramanti, Placido ^a   De Sarro, Angelina ^a   Thiemermann, Christoph ^b   Cuzzocrea, Salvatore ^a  

^a UNIVERSITY OF MESSINA   (Italy)

^b QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^c University of Bath   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

3 AMINOBENZAMIDE; 5 AMINOISOQUINOLINONE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MYELOPEROXIDASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; CONVALESCENCE; DNA BINDING; DRUG BINDING; DRUG EFFICACY; DRUG INHIBITION; EDEMA; ENZYME ACTIVATION; IMMUNOREACTIVITY; MALE; MOTOR PERFORMANCE; MOUSE; MYELITIS; NEUTROPHIL CHEMOTAXIS; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SPINAL CORD INJURY;

ANIMALS; APOPTOSIS; BENZAMIDES; BLOTTING, WESTERN; CELL NUCLEUS; DENSITOMETRY; ELECTROPHORETIC MOBILITY SHIFT ASSAY; ENZYME ACTIVATION; ENZYME INHIBITORS; I-KAPPA B PROTEINS; IN SITU NICK-END LABELING; ISOQUINOLINES; MALE; MICE; NEUTROPHILS; NF-KAPPA B; PEROXIDASE; POLY(ADP-RIBOSE) POLYMERASES; SIGNAL TRANSDUCTION; SPINAL CORD; SPINAL CORD INJURIES;

EID: 13244252358     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: 10.1124/jpet.104.076711     Document Type: Article

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