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Volumn 13, Issue 7, 2009, Pages 673-681

Effects of Etanercept and Minocycline in a rat model of spinal cord injury

Author keywords

Microglia; Pain; Spinal cord injury; TNF

Indexed keywords

ETANERCEPT; MINOCYCLINE; PROTEIN C FOS; TUMOR NECROSIS FACTOR ALPHA;

EID: 67649159074     PISSN: 10903801     EISSN: 15322149     Source Type: Journal    
DOI: 10.1016/j.ejpain.2008.08.001     Document Type: Article
Times cited : (131)

References (60)
  • 2
    • 33745457705 scopus 로고    scopus 로고
    • Minocycline inhibits poly(ADP-ribose) polymerase-1 at nanomolar concentrations.
    • Alano C.C., Kauppinen T.M., Valls A.V., and Swanson R.A. Minocycline inhibits poly(ADP-ribose) polymerase-1 at nanomolar concentrations. Proc Natl Acad Sci USA 103 (2006) 9685-9690
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 9685-9690
    • Alano, C.C.1    Kauppinen, T.M.2    Valls, A.V.3    Swanson, R.A.4
  • 3
    • 33846463481 scopus 로고    scopus 로고
    • Increased spinal c-Fos expression with noxious and non-noxious peripheral stimulation after severe spinal contusion
    • Berrocal Y.A., Pearse D.D., Andrade C.M., Hechtman J.F., Puentes R., and Eaton M.J. Increased spinal c-Fos expression with noxious and non-noxious peripheral stimulation after severe spinal contusion. Neurosci Lett 413 (2007) 58-62
    • (2007) Neurosci Lett , vol.413 , pp. 58-62
    • Berrocal, Y.A.1    Pearse, D.D.2    Andrade, C.M.3    Hechtman, J.F.4    Puentes, R.5    Eaton, M.J.6
  • 4
    • 33847261481 scopus 로고    scopus 로고
    • Transient neuroprotection by minocycline following traumatic brain injury is associated with attenuated microglial activation but no changes in cell apoptosis or neutrophil infiltration
    • Bye N., Habgood M.D., Callaway J.K., Malakooti N., Potter A., Kossmann T., et al. Transient neuroprotection by minocycline following traumatic brain injury is associated with attenuated microglial activation but no changes in cell apoptosis or neutrophil infiltration. Exp Neurol 204 (2007) 220-233
    • (2007) Exp Neurol , vol.204 , pp. 220-233
    • Bye, N.1    Habgood, M.D.2    Callaway, J.K.3    Malakooti, N.4    Potter, A.5    Kossmann, T.6
  • 5
    • 0037366864 scopus 로고    scopus 로고
    • Molecular differences in anticytokine therapies
    • Calabrese L.H. Molecular differences in anticytokine therapies. Clin Exp Rheumatol 21 (2003) 241-248
    • (2003) Clin Exp Rheumatol , vol.21 , pp. 241-248
    • Calabrese, L.H.1
  • 6
    • 0030275982 scopus 로고    scopus 로고
    • Mechanical and thermal allodynia in chronic central pain following spinal cord injury
    • Christensen M.D., Everhart A.W., Pickelman J.T., and Hulsebosch C.E. Mechanical and thermal allodynia in chronic central pain following spinal cord injury. Pain 68 (1996) 97-107
    • (1996) Pain , vol.68 , pp. 97-107
    • Christensen, M.D.1    Everhart, A.W.2    Pickelman, J.T.3    Hulsebosch, C.E.4
  • 7
    • 34250025930 scopus 로고    scopus 로고
    • Etanercept: a review of its use in the management of rheumatoid arthritis
    • Dhillon S., Lyseng-Williamson K.A., and Scott L.J. Etanercept: a review of its use in the management of rheumatoid arthritis. Drugs 67 (2007) 1211-1241
    • (2007) Drugs , vol.67 , pp. 1211-1241
    • Dhillon, S.1    Lyseng-Williamson, K.A.2    Scott, L.J.3
  • 8
    • 1242314826 scopus 로고    scopus 로고
    • Spinal cord injury pain--mechanisms and treatment
    • Finnerup N.B., and Jensen T.S. Spinal cord injury pain--mechanisms and treatment. Eur J Neurol 11 (2004) 73-82
    • (2004) Eur J Neurol , vol.11 , pp. 73-82
    • Finnerup, N.B.1    Jensen, T.S.2
  • 10
    • 0034578906 scopus 로고    scopus 로고
    • Thalidomide treatment in chronic constrictive neuropathy decreases endoneurial tumor necrosis factor-alpha, increases interleukin-10 and has long-term effects on spinal cord dorsal horn met-enkephalin
    • George A., Marziniak M., Schafers M., Toyka K.V., and Sommer C. Thalidomide treatment in chronic constrictive neuropathy decreases endoneurial tumor necrosis factor-alpha, increases interleukin-10 and has long-term effects on spinal cord dorsal horn met-enkephalin. Pain 88 (2000) 267-275
    • (2000) Pain , vol.88 , pp. 267-275
    • George, A.1    Marziniak, M.2    Schafers, M.3    Toyka, K.V.4    Sommer, C.5
  • 11
    • 34547614456 scopus 로고    scopus 로고
    • Spinal AMPA receptor inhibition attenuates mechanical allodynia and neuronal hyperexcitability following spinal cord injury in rats
    • Gwak Y.S., Kang J., Leem J.W., and Hulsebosch C.E. Spinal AMPA receptor inhibition attenuates mechanical allodynia and neuronal hyperexcitability following spinal cord injury in rats. J Neurosci Res 85 (2007) 2352-2359
    • (2007) J Neurosci Res , vol.85 , pp. 2352-2359
    • Gwak, Y.S.1    Kang, J.2    Leem, J.W.3    Hulsebosch, C.E.4
  • 12
    • 33746679191 scopus 로고    scopus 로고
    • Activation of spinal GABA receptors attenuates chronic central neuropathic pain after spinal cord injury
    • Gwak Y.S., Tan H.Y., Nam T.S., Paik K.S., Hulsebosch C.E., and Leem J.W. Activation of spinal GABA receptors attenuates chronic central neuropathic pain after spinal cord injury. J Neurotrauma 23 (2006) 1111-1124
    • (2006) J Neurotrauma , vol.23 , pp. 1111-1124
    • Gwak, Y.S.1    Tan, H.Y.2    Nam, T.S.3    Paik, K.S.4    Hulsebosch, C.E.5    Leem, J.W.6
  • 13
    • 33646439133 scopus 로고    scopus 로고
    • Activated microglia contribute to the maintenance of chronic pain after spinal cord injury
    • Hains B.C., and Waxman S.G. Activated microglia contribute to the maintenance of chronic pain after spinal cord injury. J Neurosci 26 (2006) 4308-4317
    • (2006) J Neurosci , vol.26 , pp. 4308-4317
    • Hains, B.C.1    Waxman, S.G.2
  • 14
    • 17444392322 scopus 로고    scopus 로고
    • Neuroprotection and acute spinal cord injury: a reappraisal
    • Hall E.D., and Springer J.E. Neuroprotection and acute spinal cord injury: a reappraisal. NeuroRx 1 (2004) 80-100
    • (2004) NeuroRx , vol.1 , pp. 80-100
    • Hall, E.D.1    Springer, J.E.2
  • 15
    • 0023924046 scopus 로고
    • A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia
    • Hargreaves K., Dubner R., Brown F., Flores C., and Joris J. A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia. Pain 32 (1988) 77-88
    • (1988) Pain , vol.32 , pp. 77-88
    • Hargreaves, K.1    Dubner, R.2    Brown, F.3    Flores, C.4    Joris, J.5
  • 16
    • 0037085719 scopus 로고    scopus 로고
    • Expression of fractalkine (CX3CL1) and its receptor, CX3CR1, during acute and chronic inflammation in the rodent
    • Hughes P.M., Botham M.S., Frentzel S., Mir A., and Perry V.H. Expression of fractalkine (CX3CL1) and its receptor, CX3CR1, during acute and chronic inflammation in the rodent. Glia 37 (2002) 314-327
    • (2002) Glia , vol.37 , pp. 314-327
    • Hughes, P.M.1    Botham, M.S.2    Frentzel, S.3    Mir, A.4    Perry, V.H.5
  • 17
    • 17844394930 scopus 로고    scopus 로고
    • From discovery to clinical trials: treatment strategies for central neuropathic pain after spinal cord injury
    • Hulsebosch C.E. From discovery to clinical trials: treatment strategies for central neuropathic pain after spinal cord injury. Curr Pharm Des 11 (2005) 1411-1420
    • (2005) Curr Pharm Des , vol.11 , pp. 1411-1420
    • Hulsebosch, C.E.1
  • 18
    • 7944238825 scopus 로고    scopus 로고
    • Cell signaling and the genesis of neuropathic pain
    • Ji R.R., and Strichartz G. Cell signaling and the genesis of neuropathic pain. Sci STKE 2004 252 (2004) re 14
    • (2004) Sci STKE , vol.2004 , Issue.252
    • Ji, R.R.1    Strichartz, G.2
  • 20
    • 17044417657 scopus 로고    scopus 로고
    • Minocycline attenuates mechanical allodynia and proinflammatory cytokine expression in rat models of pain facilitation
    • Ledeboer A., Sloane E.M., Milligan E.D., Frank M.G., Mahony J.H., Maier S.F., et al. Minocycline attenuates mechanical allodynia and proinflammatory cytokine expression in rat models of pain facilitation. Pain 115 (2005) 71-83
    • (2005) Pain , vol.115 , pp. 71-83
    • Ledeboer, A.1    Sloane, E.M.2    Milligan, E.D.3    Frank, M.G.4    Mahony, J.H.5    Maier, S.F.6
  • 21
    • 0034595723 scopus 로고    scopus 로고
    • Effects of neutralizing antibodies to TNF-alpha on pain-related behavior and nerve regeneration in mice with chronic constriction injury
    • Lindenlaub T., Teuteberg P., Hartung T., and Sommer C. Effects of neutralizing antibodies to TNF-alpha on pain-related behavior and nerve regeneration in mice with chronic constriction injury. Brain Res 866 1-2 (2000) 15-22
    • (2000) Brain Res , vol.866 , Issue.1-2 , pp. 15-22
    • Lindenlaub, T.1    Teuteberg, P.2    Hartung, T.3    Sommer, C.4
  • 22
    • 0038819417 scopus 로고    scopus 로고
    • Cytokines in sural nerve biopsies from inflammatory and non-inflammatory neuropathies
    • Lindenlaub T., and Sommer C. Cytokines in sural nerve biopsies from inflammatory and non-inflammatory neuropathies. Acta Neuropathol 105 6 (2003) 593-602
    • (2003) Acta Neuropathol , vol.105 , Issue.6 , pp. 593-602
    • Lindenlaub, T.1    Sommer, C.2
  • 23
    • 21544469729 scopus 로고    scopus 로고
    • Induction of CX3CL1 expression in astrocytes and CX3CR1 in microglia in the spinal cord of a rat model of neuropathic pain
    • Lindia J.A., McGowan E., Jochnowitz N., and Abbadie C. Induction of CX3CL1 expression in astrocytes and CX3CR1 in microglia in the spinal cord of a rat model of neuropathic pain. J Pain 6 (2005) 434-438
    • (2005) J Pain , vol.6 , pp. 434-438
    • Lindia, J.A.1    McGowan, E.2    Jochnowitz, N.3    Abbadie, C.4
  • 25
    • 8144221210 scopus 로고    scopus 로고
    • Evidence that exogenous and endogenous fractalkine can induce spinal nociceptive facilitation in rats
    • Milligan E.D., Zapata V., Chacur M., Schoeniger D., Biedenkapp J., O'Connor K.A., et al. Evidence that exogenous and endogenous fractalkine can induce spinal nociceptive facilitation in rats. Eur J Neurosci 20 (2004) 2294-2302
    • (2004) Eur J Neurosci , vol.20 , pp. 2294-2302
    • Milligan, E.D.1    Zapata, V.2    Chacur, M.3    Schoeniger, D.4    Biedenkapp, J.5    O'Connor, K.A.6
  • 26
    • 2442489671 scopus 로고    scopus 로고
    • TNF-alpha and TNF-alpha receptor type 1 upregulation in glia and neurons after peripheral nerve injury: studies in murine DRG and spinal cord
    • Ohtori S., Takahashi K., Moriya H., and Myers R.R. TNF-alpha and TNF-alpha receptor type 1 upregulation in glia and neurons after peripheral nerve injury: studies in murine DRG and spinal cord. Spine 29 (2004) 1082-1088
    • (2004) Spine , vol.29 , pp. 1082-1088
    • Ohtori, S.1    Takahashi, K.2    Moriya, H.3    Myers, R.R.4
  • 27
    • 33746354314 scopus 로고    scopus 로고
    • Fractalkine and minocycline alter neuronal activity in the spinal cord dorsal horn
    • Owolabi S.A., and Saab C.Y. Fractalkine and minocycline alter neuronal activity in the spinal cord dorsal horn. FEBS Lett 580 (2006) 4306-4310
    • (2006) FEBS Lett , vol.580 , pp. 4306-4310
    • Owolabi, S.A.1    Saab, C.Y.2
  • 28
    • 10944236178 scopus 로고    scopus 로고
    • Inhibition of tumour necrosis factor-alpha by antisense targeting produces immunophenotypical and morphological changes in injury-activated microglia and macrophages
    • Pearse D.D., Pereira F.C., Stolyarova A., Barakat D.J., and Bunge M.B. Inhibition of tumour necrosis factor-alpha by antisense targeting produces immunophenotypical and morphological changes in injury-activated microglia and macrophages. Eur J Neurosci 20 (2004) 3387-3396
    • (2004) Eur J Neurosci , vol.20 , pp. 3387-3396
    • Pearse, D.D.1    Pereira, F.C.2    Stolyarova, A.3    Barakat, D.J.4    Bunge, M.B.5
  • 29
    • 33646379090 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha contributes to below-level neuropathic pain after spinal cord injury
    • Peng X.M., Zhou Z.G., Glorioso J.C., Fink D.J., and Mata M. Tumor necrosis factor-alpha contributes to below-level neuropathic pain after spinal cord injury. Ann Neurol 59 (2006) 843-851
    • (2006) Ann Neurol , vol.59 , pp. 843-851
    • Peng, X.M.1    Zhou, Z.G.2    Glorioso, J.C.3    Fink, D.J.4    Mata, M.5
  • 30
    • 33845568271 scopus 로고    scopus 로고
    • Proinflammatory cytokine synthesis in the injured mouse spinal cord: multiphasic expression pattern and identification of the cell types involved
    • Pineau I., and Lacroix S. Proinflammatory cytokine synthesis in the injured mouse spinal cord: multiphasic expression pattern and identification of the cell types involved. J Comp Neurol 500 (2007) 267-285
    • (2007) J Comp Neurol , vol.500 , pp. 267-285
    • Pineau, I.1    Lacroix, S.2
  • 31
    • 0037622717 scopus 로고    scopus 로고
    • Inhibition of microglial activation attenuates the development but not existing hypersensitivity in a rat model of neuropathy
    • Raghavendra V., Tanga F., and DeLeo J.A. Inhibition of microglial activation attenuates the development but not existing hypersensitivity in a rat model of neuropathy. J Pharmacol Exp Ther 306 (2003) 624-630
    • (2003) J Pharmacol Exp Ther , vol.306 , pp. 624-630
    • Raghavendra, V.1    Tanga, F.2    DeLeo, J.A.3
  • 32
    • 0033835476 scopus 로고    scopus 로고
    • Intrathecally administered endotoxin or cytokines produce allodynia, hyperalgesia and changes in spinal cord neuronal responses to nociceptive stimuli in the rat
    • Reeve A.J., Patel S., Fox A., Walker K., and Urban L. Intrathecally administered endotoxin or cytokines produce allodynia, hyperalgesia and changes in spinal cord neuronal responses to nociceptive stimuli in the rat. Eur J Pain 4 3 (2000) 247-257
    • (2000) Eur J Pain , vol.4 , Issue.3 , pp. 247-257
    • Reeve, A.J.1    Patel, S.2    Fox, A.3    Walker, K.4    Urban, L.5
  • 33
    • 0037294433 scopus 로고    scopus 로고
    • Selective increase of tumour necrosis factor-alpha in injured and spared myelinated primary afferents after chronic constrictive injury of rat sciatic nerve
    • Schafers M., Geis C., Svensson C.I., Luo Z.D., and Sommer C. Selective increase of tumour necrosis factor-alpha in injured and spared myelinated primary afferents after chronic constrictive injury of rat sciatic nerve. Eur J Neurosci 17 (2003) 791-804
    • (2003) Eur J Neurosci , vol.17 , pp. 791-804
    • Schafers, M.1    Geis, C.2    Svensson, C.I.3    Luo, Z.D.4    Sommer, C.5
  • 34
    • 17144451153 scopus 로고    scopus 로고
    • Increased sensitivity of injured and adjacent uninjured rat primary sensory neurons to exogenous tumor necrosis factor-alpha after spinal nerve ligation
    • Schafers M., Lee D.H., Brors D., Yaksh T.L., and Sorkin L.S. Increased sensitivity of injured and adjacent uninjured rat primary sensory neurons to exogenous tumor necrosis factor-alpha after spinal nerve ligation. J Neurosci 23 (2003) 3028-3038
    • (2003) J Neurosci , vol.23 , pp. 3028-3038
    • Schafers, M.1    Lee, D.H.2    Brors, D.3    Yaksh, T.L.4    Sorkin, L.S.5
  • 35
    • 0345701254 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha induces mechanical allodynia after spinal nerve ligation by activation of p38 MAPK in primary sensory neurons
    • Schafers M., Svensson C.I., Sommer C., and Sorkin L.S. Tumor necrosis factor-alpha induces mechanical allodynia after spinal nerve ligation by activation of p38 MAPK in primary sensory neurons. J Neurosci 23 (2003) 2517-2521
    • (2003) J Neurosci , vol.23 , pp. 2517-2521
    • Schafers, M.1    Svensson, C.I.2    Sommer, C.3    Sorkin, L.S.4
  • 36
    • 35548937457 scopus 로고    scopus 로고
    • The neuropathic pain triad: neurons, immune cells and glia
    • Scholz J., and Woolf C.J. The neuropathic pain triad: neurons, immune cells and glia. Nat Neurosci 10 (2007) 1361-1368
    • (2007) Nat Neurosci , vol.10 , pp. 1361-1368
    • Scholz, J.1    Woolf, C.J.2
  • 37
    • 0033385643 scopus 로고    scopus 로고
    • C-fos expression in the spinal cord of rats exhibiting allodynia following contusive spinal cord injury
    • Siddall P.J., Xu C.L., Floyd N., and Keay K.A. C-fos expression in the spinal cord of rats exhibiting allodynia following contusive spinal cord injury. Brain Res 851 (1999) 281-286
    • (1999) Brain Res , vol.851 , pp. 281-286
    • Siddall, P.J.1    Xu, C.L.2    Floyd, N.3    Keay, K.A.4
  • 38
    • 0035860577 scopus 로고    scopus 로고
    • Anti-TNF-neutralizing antibodies reduce pain-related behavior in two different mouse models of painful mononeuropathy
    • Sommer C., Lindenlaub T., Teuteberg P., Schafers M., Hartung T., and Toyka K.V. Anti-TNF-neutralizing antibodies reduce pain-related behavior in two different mouse models of painful mononeuropathy. Brain Res 913 (2001) 86-89
    • (2001) Brain Res , vol.913 , pp. 86-89
    • Sommer, C.1    Lindenlaub, T.2    Teuteberg, P.3    Schafers, M.4    Hartung, T.5    Toyka, K.V.6
  • 39
  • 40
    • 0032536413 scopus 로고    scopus 로고
    • Painful mononeuropathy in C57BL/Wld mice with delayed wallerian degeneration: differential effects of cytokine production and nerve regeneration on thermal and mechanical hypersensitivity
    • Sommer C., and Schäfers M. Painful mononeuropathy in C57BL/Wld mice with delayed wallerian degeneration: differential effects of cytokine production and nerve regeneration on thermal and mechanical hypersensitivity. Brain Res 784 1-2 (1998) 154-162
    • (1998) Brain Res , vol.784 , Issue.1-2 , pp. 154-162
    • Sommer, C.1    Schäfers, M.2
  • 41
    • 1542376941 scopus 로고    scopus 로고
    • Minocycline treatment reduces delayed oligodendrocyte death, attenuates axonal dieback, and improves functional outcome after spinal cord injury
    • Stirling D.P., Khodarahmi K., Liu J., McPhail L.T., McBride C.B., Steeves J.D., et al. Minocycline treatment reduces delayed oligodendrocyte death, attenuates axonal dieback, and improves functional outcome after spinal cord injury. J Neurosci 24 (2004) 2182-2190
    • (2004) J Neurosci , vol.24 , pp. 2182-2190
    • Stirling, D.P.1    Khodarahmi, K.2    Liu, J.3    McPhail, L.T.4    McBride, C.B.5    Steeves, J.D.6
  • 42
    • 17444408199 scopus 로고    scopus 로고
    • Spinal blockade of TNF blocks spinal nerve ligation-induced increases in spinal P-p38
    • Svensson C.I., Schafers M., Jones T.L., Powell H., and Sorkin L.S. Spinal blockade of TNF blocks spinal nerve ligation-induced increases in spinal P-p38. Neurosci Lett 379 (2005) 209-213
    • (2005) Neurosci Lett , vol.379 , pp. 209-213
    • Svensson, C.I.1    Schafers, M.2    Jones, T.L.3    Powell, H.4    Sorkin, L.S.5
  • 43
    • 0035857748 scopus 로고    scopus 로고
    • Intrathecal interleukin-1 receptor antagonist in combination with soluble tumor necrosis factor receptor exhibits an anti-allodynic action in a rat model of neuropathic pain
    • Sweitzer S., Martin D., and DeLeo J.A. Intrathecal interleukin-1 receptor antagonist in combination with soluble tumor necrosis factor receptor exhibits an anti-allodynic action in a rat model of neuropathic pain. Neuroscience 103 (2001) 529-539
    • (2001) Neuroscience , vol.103 , pp. 529-539
    • Sweitzer, S.1    Martin, D.2    DeLeo, J.A.3
  • 44
    • 60949105934 scopus 로고    scopus 로고
    • CCL2 is a key mediator of microglia activation in neuropathic pain states
    • Thacker M.A., Clark A.K., Bishop T., Grist J., Yip P.K., Moon L.D., et al. CCL2 is a key mediator of microglia activation in neuropathic pain states. Eur J Pain 13 (2008) 263-272
    • (2008) Eur J Pain , vol.13 , pp. 263-272
    • Thacker, M.A.1    Clark, A.K.2    Bishop, T.3    Grist, J.4    Yip, P.K.5    Moon, L.D.6
  • 45
    • 1642404488 scopus 로고    scopus 로고
    • Enhanced production of monocyte chemoattractant protein-1 in the dorsal root ganglia in a rat model of neuropathic pain: possible involvement in the development of neuropathic pain
    • Tanaka T., Minami M., Nakagawa T., and Satoh M. Enhanced production of monocyte chemoattractant protein-1 in the dorsal root ganglia in a rat model of neuropathic pain: possible involvement in the development of neuropathic pain. Neurosci Res 78 (2004) 463-469
    • (2004) Neurosci Res , vol.78 , pp. 463-469
    • Tanaka, T.1    Minami, M.2    Nakagawa, T.3    Satoh, M.4
  • 46
    • 0035876916 scopus 로고    scopus 로고
    • Minocycline provides neuroprotection against N-methyl-D-aspartate neurotoxicity by inhibiting microglia
    • Tikka T.M., and Koistinaho J.E. Minocycline provides neuroprotection against N-methyl-D-aspartate neurotoxicity by inhibiting microglia. J Immunol 166 (2001) 7527-7533
    • (2001) J Immunol , vol.166 , pp. 7527-7533
    • Tikka, T.M.1    Koistinaho, J.E.2
  • 47
    • 0042968804 scopus 로고    scopus 로고
    • P2X4 receptors induced in spinal microglia gate tactile allodynia after nerve injury
    • Tsuda M., Shigemoto-Mogami Y., Koizumi S., Mizokoshi A., Kohsaka S., Salter M.W., et al. P2X4 receptors induced in spinal microglia gate tactile allodynia after nerve injury. Nature 424 (2003) 778-783
    • (2003) Nature , vol.424 , pp. 778-783
    • Tsuda, M.1    Shigemoto-Mogami, Y.2    Koizumi, S.3    Mizokoshi, A.4    Kohsaka, S.5    Salter, M.W.6
  • 48
    • 34347402769 scopus 로고    scopus 로고
    • Differential expression of cytokines in painful and painless neuropathies
    • Uçeyler N., Rogausch J.P., Toyka K.V., and Sommer C. Differential expression of cytokines in painful and painless neuropathies. Neurology 69 1 (2007) 42-49
    • (2007) Neurology , vol.69 , Issue.1 , pp. 42-49
    • Uçeyler, N.1    Rogausch, J.P.2    Toyka, K.V.3    Sommer, C.4
  • 49
    • 4544252839 scopus 로고    scopus 로고
    • Fractalkine (CX3CL1) and fractalkine receptor (CX3CR1) distribution in spinal cord and dorsal root ganglia under basal and neuropathic pain conditions
    • Verge G.M., Milligan E.D., Maier S.F., Watkins L.R., Naeve G.S., and Foster A.C. Fractalkine (CX3CL1) and fractalkine receptor (CX3CR1) distribution in spinal cord and dorsal root ganglia under basal and neuropathic pain conditions. Eur J Neurosci 20 (2004) 1150-1160
    • (2004) Eur J Neurosci , vol.20 , pp. 1150-1160
    • Verge, G.M.1    Milligan, E.D.2    Maier, S.F.3    Watkins, L.R.4    Naeve, G.S.5    Foster, A.C.6
  • 50
    • 4043079197 scopus 로고    scopus 로고
    • P2X7 receptor inhibition improves recovery after spinal cord injury
    • Wang X., Arcuino G., Takano T., Lin J., Peng W.G., Wan P., et al. P2X7 receptor inhibition improves recovery after spinal cord injury. Nat Med 10 (2004) 821-827
    • (2004) Nat Med , vol.10 , pp. 821-827
    • Wang, X.1    Arcuino, G.2    Takano, T.3    Lin, J.4    Peng, W.G.5    Wan, P.6
  • 51
    • 0035426434 scopus 로고    scopus 로고
    • Glial activation: a driving force for pathological pain
    • Watkins L.R., Milligan E.D., and Maier F. Glial activation: a driving force for pathological pain. Trends Neurosci 24 (2001) 450-455
    • (2001) Trends Neurosci , vol.24 , pp. 450-455
    • Watkins, L.R.1    Milligan, E.D.2    Maier, F.3
  • 52
    • 0034882399 scopus 로고    scopus 로고
    • Spinal cord glia: new players in pain
    • Watkins L.R., Milligan E.D., and Maier S.F. Spinal cord glia: new players in pain. Pain 93 (2001) 201-205
    • (2001) Pain , vol.93 , pp. 201-205
    • Watkins, L.R.1    Milligan, E.D.2    Maier, S.F.3
  • 53
    • 17844406364 scopus 로고    scopus 로고
    • Severity-dependent expression of pro-inflammatory cytokines in traumatic spinal cord injury in the rat
    • Yang L., Jones N.R., Blumbergs P.C., Van Den H.C., Moore E.J., Manavis J., et al. Severity-dependent expression of pro-inflammatory cytokines in traumatic spinal cord injury in the rat. J Clin Neurosci 12 (2005) 276-284
    • (2005) J Clin Neurosci , vol.12 , pp. 276-284
    • Yang, L.1    Jones, N.R.2    Blumbergs, P.C.3    Van Den, H.C.4    Moore, E.J.5    Manavis, J.6
  • 54
    • 26244448465 scopus 로고    scopus 로고
    • Spinal cord injury: a model of central neuropathic pain
    • Yezierski R.P. Spinal cord injury: a model of central neuropathic pain. Neurosignals 14 (2005) 182-193
    • (2005) Neurosignals , vol.14 , pp. 182-193
    • Yezierski, R.P.1
  • 55
    • 21844437380 scopus 로고    scopus 로고
    • Intraneural injection of interleukin-1beta and tumor necrosis factor-alpha into rat sciatic nerve at physiological doses induces signs of neuropathic pain
    • Zelenka M., Schafers M., and Sommer C. Intraneural injection of interleukin-1beta and tumor necrosis factor-alpha into rat sciatic nerve at physiological doses induces signs of neuropathic pain. Pain 116 (2005) 257-263
    • (2005) Pain , vol.116 , pp. 257-263
    • Zelenka, M.1    Schafers, M.2    Sommer, C.3
  • 56
    • 36048991728 scopus 로고    scopus 로고
    • Expression of CCR2 in both resident and bone marrow-derived microglia plays a critical role in neuropathic pain
    • Zhang J., Shi X.Q., Echeverry S., Mogil J.S., De Koninck Y., and Rivest S. Expression of CCR2 in both resident and bone marrow-derived microglia plays a critical role in neuropathic pain. J Neurosci 27 45 (2007) 12396-12406
    • (2007) J Neurosci , vol.27 , Issue.45 , pp. 12396-12406
    • Zhang, J.1    Shi, X.Q.2    Echeverry, S.3    Mogil, J.S.4    De Koninck, Y.5    Rivest, S.6
  • 57
    • 0037440419 scopus 로고    scopus 로고
    • Suppression of activated microglia promotes survival and function of transplanted oligodendroglial progenitors
    • Zhang S.C., Goetz B.D., and Duncan I.D. Suppression of activated microglia promotes survival and function of transplanted oligodendroglial progenitors. Glia 41 (2003) 191-198
    • (2003) Glia , vol.41 , pp. 191-198
    • Zhang, S.C.1    Goetz, B.D.2    Duncan, I.D.3
  • 58
    • 33847337984 scopus 로고    scopus 로고
    • Extracellular signal-regulated kinase-regulated microglia-neuron signaling by prostaglandin E2 contributes to pain after spinal cord injury
    • Zhao P., Waxman S.G., and Hains B.C. Extracellular signal-regulated kinase-regulated microglia-neuron signaling by prostaglandin E2 contributes to pain after spinal cord injury. J Neurosci 27 (2007) 2357-2368
    • (2007) J Neurosci , vol.27 , pp. 2357-2368
    • Zhao, P.1    Waxman, S.G.2    Hains, B.C.3
  • 59
    • 0037007645 scopus 로고    scopus 로고
    • Minocycline inhibits cytochrome c release and delays progression of amyotrophic lateral sclerosis in mice
    • Zhu S., Stavrovskaya I.G., Drozda M., Kim B.Y., Ona V., Li M., et al. Minocycline inhibits cytochrome c release and delays progression of amyotrophic lateral sclerosis in mice. Nature 417 (2002) 74-78
    • (2002) Nature , vol.417 , pp. 74-78
    • Zhu, S.1    Stavrovskaya, I.G.2    Drozda, M.3    Kim, B.Y.4    Ona, V.5    Li, M.6
  • 60
    • 0020525719 scopus 로고
    • Committee for research and ethical issues of the IASP
    • Zimmerman A. Committee for research and ethical issues of the IASP. Pain 16 (1983) 109-110
    • (1983) Pain , vol.16 , pp. 109-110
    • Zimmerman, A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.