메뉴 건너뛰기




Volumn 47, Issue 6 SUPPL. 4, 1996, Pages

The pharmacology and mechanism of action of riluzole

(1)  Doble, A a  

a SANOFI   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AMPA RECEPTOR; CARBAMAZEPINE; DIAZEPAM; DIZOCILPINE; EXCITOTOXIN; GLUTAMATE RECEPTOR; GLUTAMIC ACID; GUANINE NUCLEOTIDE BINDING PROTEIN; KAINIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PERTUSSIS TOXIN; RILUZOLE; SODIUM CHANNEL; VERATRIDINE;

EID: 0029753270     PISSN: 00283878     EISSN: None     Source Type: Journal    
DOI: 10.1212/wnl.47.6_suppl_4.233s     Document Type: Review
Times cited : (583)

References (30)
  • 2
    • 0025063609 scopus 로고
    • Excitatory amino acid neurotoxicity and neurodegenerative disease
    • Meldrum B, Garthwaite J. Excitatory amino acid neurotoxicity and neurodegenerative disease. Trends Pharmacol Sci 1990;11:379-387.
    • (1990) Trends Pharmacol Sci , vol.11 , pp. 379-387
    • Meldrum, B.1    Garthwaite, J.2
  • 3
    • 0028762647 scopus 로고
    • Excitatory amino acids as a final common pathway for neurologic disorders
    • Lipton SA, Rosenberg PA. Excitatory amino acids as a final common pathway for neurologic disorders. New Engl J Med 1994;330:613-622.
    • (1994) New Engl J Med , vol.330 , pp. 613-622
    • Lipton, S.A.1    Rosenberg, P.A.2
  • 5
    • 0029732866 scopus 로고    scopus 로고
    • Excitotoxicity in ALS
    • Leigh PN, Meldrum BS. Excitotoxicity in ALS. Neurology 1996;47(suppl 4):S221-S227.
    • (1996) Neurology , vol.47 , Issue.4 SUPPL.
    • Leigh, P.N.1    Meldrum, B.S.2
  • 6
    • 0022362589 scopus 로고
    • 2-amino-6-trifluoromethoxybenzothiazole, a possible antagonist of excitatory amino acid neurotransmission. I. Anticonvulsant properties
    • Mizoule J, Meldrum B, Mazadier M, et al. 2-amino-6-trifluoromethoxybenzothiazole, a possible antagonist of excitatory amino acid neurotransmission. I. Anticonvulsant properties. Neuropharmacology 1985;24:767-773.
    • (1985) Neuropharmacology , vol.24 , pp. 767-773
    • Mizoule, J.1    Meldrum, B.2    Mazadier, M.3
  • 7
    • 0022384359 scopus 로고
    • 2-amino-6-trifluoromethoxybenzothiazole, a possible antagonist of excitatory amino acid neurotransmission. II. Biochemical properties
    • Benavides J, Camelin JC, Mitrani N, et al. 2-amino-6-trifluoromethoxybenzothiazole, a possible antagonist of excitatory amino acid neurotransmission. II. Biochemical properties. Neuropharmacology 1985;24:1085-1092.
    • (1985) Neuropharmacology , vol.24 , pp. 1085-1092
    • Benavides, J.1    Camelin, J.C.2    Mitrani, N.3
  • 8
    • 0024500877 scopus 로고
    • 3H]-aspartate release from cultured cerebellar granule cells
    • 3H]-aspartate release from cultured cerebellar granule cells. Neurosci Lett 1989;96:345-350.
    • (1989) Neurosci Lett , vol.96 , pp. 345-350
    • Hubert, J.P.1    Doble, A.2
  • 9
    • 0025213383 scopus 로고
    • Glutamate receptors of a quisqualate-kainate subtype are involved in the presynaptic regulation of dopamine release in the cat caudate nucleus in vivo
    • Barbeito L, Cheramy A, Godeheu G, et al. Glutamate receptors of a quisqualate-kainate subtype are involved in the presynaptic regulation of dopamine release in the cat caudate nucleus in vivo. Eur J Neurosci 1990;2:304-311.
    • (1990) Eur J Neurosci , vol.2 , pp. 304-311
    • Barbeito, L.1    Cheramy, A.2    Godeheu, G.3
  • 10
    • 0027213025 scopus 로고
    • Inhibition by riluzole of electrophysiological responses mediated by rat kainate and NMDA receptors expressed in Xenopus oocytes
    • Debono MW, Le Guern J, Canton T, et al. Inhibition by riluzole of electrophysiological responses mediated by rat kainate and NMDA receptors expressed in Xenopus oocytes. Eur J Pharmacol 1993;235:283-289.
    • (1993) Eur J Pharmacol , vol.235 , pp. 283-289
    • Debono, M.W.1    Le Guern, J.2    Canton, T.3
  • 11
    • 0028058808 scopus 로고
    • Antagonism by riluzole of entry of calcium evoked by NMDA and veratridine in rat cultured granule cells: Evidence for a dual mechanism of action
    • Hubert JP, Delumeau JC, Glowinski J, et al. Antagonism by riluzole of entry of calcium evoked by NMDA and veratridine in rat cultured granule cells: evidence for a dual mechanism of action. Br J Pharmacol 1994;113:261-267.
    • (1994) Br J Pharmacol , vol.113 , pp. 261-267
    • Hubert, J.P.1    Delumeau, J.C.2    Glowinski, J.3
  • 12
    • 0027762836 scopus 로고
    • The neuroprotective agent riluzole inhibits release of glutamate and aspartate from slices of hippocampal area CA1
    • Martin D, Thompson MA, Nadler JV. The neuroprotective agent riluzole inhibits release of glutamate and aspartate from slices of hippocampal area CA1. Eur J Pharmacol 1993; 250:473-476.
    • (1993) Eur J Pharmacol , vol.250 , pp. 473-476
    • Martin, D.1    Thompson, M.A.2    Nadler, J.V.3
  • 13
    • 0026490217 scopus 로고
    • Riluzole inhibits the release of glutamate in the caudate nucleus of the cat in vivo
    • Cheramy A, Barbeito L, Godeheu G, Glowinski J. Riluzole inhibits the release of glutamate in the caudate nucleus of the cat in vivo. Neurosci Lett 1992;147:209-212.
    • (1992) Neurosci Lett , vol.147 , pp. 209-212
    • Cheramy, A.1    Barbeito, L.2    Godeheu, G.3    Glowinski, J.4
  • 15
    • 0026334826 scopus 로고
    • Riluzole specifically blocks inactivated Na channels in myelinated nerve fibres
    • Benoit E, Escande D. Riluzole specifically blocks inactivated Na channels in myelinated nerve fibres. Pflügers Arch 1991; 419:603-609.
    • (1991) Pflügers Arch , vol.419 , pp. 603-609
    • Benoit, E.1    Escande, D.2
  • 16
    • 0028365121 scopus 로고
    • Block of the rat brain IIA sodium channel α subunit by the neuroprotective drug riluzole
    • Hebert T, Drapeau P, Pradier L, Dunn RJ. Block of the rat brain IIA sodium channel α subunit by the neuroprotective drug riluzole. Mol Pharmacol 1994;45:1055-1060.
    • (1994) Mol Pharmacol , vol.45 , pp. 1055-1060
    • Hebert, T.1    Drapeau, P.2    Pradier, L.3    Dunn, R.J.4
  • 17
    • 0028170251 scopus 로고
    • Neuroprotective effects of riluzole on N-methyl-D-aspartate- Or veratridine-induced neurotoxicity in rat hippocampal slices
    • Malgouris C, Daniel M, Doble A. Neuroprotective effects of riluzole on N-methyl-D-aspartate- or veratridine-induced neurotoxicity in rat hippocampal slices. Eur J Pharmacol 1994; 177;95-99.
    • (1994) Eur J Pharmacol , vol.177 , pp. 95-99
    • Malgouris, C.1    Daniel, M.2    Doble, A.3
  • 18
    • 0029021812 scopus 로고
    • Protective effect of riluzole on excitatory amino acid-mediated neurotoxicity in motoneuron-enriched cultures
    • Estevez AG, Stutzmann JM, Barbeito L. Protective effect of riluzole on excitatory amino acid-mediated neurotoxicity in motoneuron-enriched cultures. Eur J Pharmacol 1995;280:47-53.
    • (1995) Eur J Pharmacol , vol.280 , pp. 47-53
    • Estevez, A.G.1    Stutzmann, J.M.2    Barbeito, L.3
  • 19
    • 0029113872 scopus 로고
    • Neuroprotective strategies in a model of chronic glutamate-mediated motor neurone toxicity
    • Rothstein JD, Kuncl RW. Neuroprotective strategies in a model of chronic glutamate-mediated motor neurone toxicity. J Neurochem 1995;65:643-651.
    • (1995) J Neurochem , vol.65 , pp. 643-651
    • Rothstein, J.D.1    Kuncl, R.W.2
  • 20
    • 0027439986 scopus 로고
    • Riluzole prevents anoxic injury in cultured cerebellar granule neurones
    • Dessi F, Ben-Ari Y, Charriaut-Marlangue C. Riluzole prevents anoxic injury in cultured cerebellar granule neurones. Eur J Pharmacol 1993;250:325-328.
    • (1993) Eur J Pharmacol , vol.250 , pp. 325-328
    • Dessi, F.1    Ben-Ari, Y.2    Charriaut-Marlangue, C.3
  • 21
    • 0027397195 scopus 로고
    • Cell culture evidence for neuronal degeneration in amyotrophic lateral sclerosis being linked to glutamate AMPA/kainate receptors
    • Couratier P, Hugon J, Sindou P, et al. Cell culture evidence for neuronal degeneration in amyotrophic lateral sclerosis being linked to glutamate AMPA/kainate receptors. Lancet 1993;341:268-270.
    • (1993) Lancet , vol.341 , pp. 268-270
    • Couratier, P.1    Hugon, J.2    Sindou, P.3
  • 22
    • 0028226708 scopus 로고
    • Neuroprotective effects of riluzole in ALS CSF toxicity
    • Couratier P, Sindou P, Esclaire F, et al. Neuroprotective effects of riluzole in ALS CSF toxicity. Neuroreport 1994;5: 1012-1014.
    • (1994) Neuroreport , vol.5 , pp. 1012-1014
    • Couratier, P.1    Sindou, P.2    Esclaire, F.3
  • 23
    • 0026767197 scopus 로고
    • Neuroprotective actions of riluzole in rodent models of global and focal ischaemia
    • Pratt J, Rataud J, Bardot F, et al. Neuroprotective actions of riluzole in rodent models of global and focal ischaemia. Neurosci Lett 1992;140:225-230.
    • (1992) Neurosci Lett , vol.140 , pp. 225-230
    • Pratt, J.1    Rataud, J.2    Bardot, F.3
  • 24
    • 0027469132 scopus 로고
    • Effect of riluzole on focal cerebral ischaemia in rats
    • Wahl F, Allix M, Plotkine M, Boulu RG. Effect of riluzole on focal cerebral ischaemia in rats. Eur J Pharmacol 1993;230: 209-214.
    • (1993) Eur J Pharmacol , vol.230 , pp. 209-214
    • Wahl, F.1    Allix, M.2    Plotkine, M.3    Boulu, R.G.4
  • 25
    • 0024307317 scopus 로고
    • Riluzole, a novel antiglutamate, prevents memory loss and hippocampal neuronal damage in ischaemic gerbils
    • Malgouris C, Bardot F, Daniel M, et al. Riluzole, a novel antiglutamate, prevents memory loss and hippocampal neuronal damage in ischaemic gerbils. J Neurosci 1989;9:3720-3727.
    • (1989) J Neurosci , vol.9 , pp. 3720-3727
    • Malgouris, C.1    Bardot, F.2    Daniel, M.3
  • 26
    • 0028598567 scopus 로고
    • Riluzole and experimental parkinsonism: Antagonism of MPTP-induced decrease in central dopamine levels in mice
    • Boireau A, Dubedat P, Bordier F, et al. Riluzole and experimental parkinsonism: antagonism of MPTP-induced decrease in central dopamine levels in mice. Neuroreport 1994;5:2657-2660.
    • (1994) Neuroreport , vol.5 , pp. 2657-2660
    • Boireau, A.1    Dubedat, P.2    Bordier, F.3
  • 27
    • 0028080303 scopus 로고
    • +-induced increase in striatal extracellular dopamine in rats in vivo
    • +-induced increase in striatal extracellular dopamine in rats in vivo. Neuroreport 1994;5:2157-2160.
    • (1994) Neuroreport , vol.5 , pp. 2157-2160
    • Boireau, A.1    Miquet, J.M.2    Dubedat, P.3
  • 28
    • 0029081625 scopus 로고
    • Riluzole prevents MPTP-induced parkinsonism in the rhesus monkey: A pilot study
    • Benazzouz A, Boraud A, Dubedat P, et al. Riluzole prevents MPTP-induced parkinsonism in the rhesus monkey: a pilot study. Eur J Pharmacol 1995;284:299-307.
    • (1995) Eur J Pharmacol , vol.284 , pp. 299-307
    • Benazzouz, A.1    Boraud, A.2    Dubedat, P.3
  • 29
    • 0030271253 scopus 로고    scopus 로고
    • Neuroprotective effects of riluzole on a model of Parkinson's disease in the rat
    • in press
    • Barnéoud P, Mazadier M, Miquet JM, et al. Neuroprotective effects of riluzole on a model of Parkinson's disease in the rat. Neuroscience 1996 (in press).
    • (1996) Neuroscience
    • Barnéoud, P.1    Mazadier, M.2    Miquet, J.M.3
  • 30
    • 0029147618 scopus 로고
    • Methamphetamine and dopaminergic neurotoxicity: Differential effects of agents interfering with glutamatergic transmission
    • Boireau A, Bordier F, Dubedat P, Doble A. Methamphetamine and dopaminergic neurotoxicity: differential effects of agents interfering with glutamatergic transmission. Neurosci Lett 1995;195:9-12.
    • (1995) Neurosci Lett , vol.195 , pp. 9-12
    • Boireau, A.1    Bordier, F.2    Dubedat, P.3    Doble, A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.