Apoptosis after traumatic human spinal cord injury

Journal of Neurosurgery

Volumn 89, Issue 6, 1998, Pages 911-920

  Emery, Evelyne ^a   Aldana, Philipp ^c   Bunge, Mary Bartlett ^c   Puckett, William ^c   Srinivasan, Anu ^c   Keane, Robert W ^c   Bethea, John ^c   Levi, Allan D O ^b  

^a BEAUJON HOSPITAL   (France)

^b UNIVERSITY OF MIAMI   (United States)

^c NONE

Author keywords

Apoptosis; Caspase 3; Human spinal cord injury

Indexed keywords

2',3' CYCLIC NUCLEOTIDE 3' PHOSPHODIESTERASE; ANTIBODY; CD45 ANTIGEN; CD68 ANTIGEN; DNA FRAGMENT; ENZYME; EOSIN; GLIAL FIBRILLARY ACIDIC PROTEIN; HEMATOXYLIN; HOE 33342; PROTEINASE; PROTEINASE INHIBITOR; TRANSFERASE;

ADOLESCENT; ADULT; AGED; APOPTOSIS; ARTICLE; CELL STRUCTURE; CONTROLLED STUDY; ENZYME ACTIVATION; FEMALE; HUMAN; HUMAN TISSUE; MALE; PRIORITY JOURNAL; SPINAL CORD INJURY;

EID: 0031783714     PISSN: 00223085     EISSN: None     Source Type: Journal    
DOI: 10.3171/jns.1998.89.6.0911     Document Type: Article

References (55)

1. Adams JC: Biotin amplification of biotin and horseradish peroxidase signals in histochemical stains. J Histochem Cytochem 40:1457-1463, 1992
2. Alnemri ES, Livingston DJ, Nicholson DW, et al: Human ICE/CED-3 protease nomenclature. Cell 87:171, 1996 (Letter)
3. Arends MJ, Wyllie AH: Apoptosis: mechanisms and roles in pathology. Int Rev Exp Pathol 32:223-254, 1991
4. Armstrong RC, Aja TJ, Hoang KD, et al: Activation of the CED3/ICE-related protease CPP32 in cerebellar granule neurons undergoing apoptosis but not necrosis. J Neurosci 17: 553-562, 1997
5. Barres BA, Jacobson MD, Schmid R: Does oligodendrocyte survival depend on axons? Curr Biol 3:489-197, 1993
6. Bauer J, Wekerle H, Lassmann H: Apoptosis in brain-specific autoimmune disease. Curr Opin Immunol 7:839-843, 1995
7. Blight AR: Effect of 4-aminopyridine on axonal conduction-block in chronic spinal cord injury. Brain Res Bull 22:47-52, 1989
8. Bracken MB, Shepard MJ, Collins WF, et al: A randomized, controlled trial of methylprednisolone or naloxone in the treatment of acute spinal-cord injury. Results of the second National Acute Spinal Cord Injury Study. N Engl J Med 322: 1405-1411, 1990
9. Bunge RP, Puckett WR, Becerra JL, et al: Observations on the pathology of human spinal cord injury. A review and classification of 22 new cases with details from a case of chronic cord compression with extensive focal demyelination. Adv Neurol 59:75-89, 1993
10. Cohen JJ: Apoptosis. Immunol Today 14:126-130, 1993
11. Crowe MJ, Bresnahan JC, Shuman SL: Apoptosis and delayed degeneration after spinal cord injury in rats and monkeys. Nature Med 3:73-76, 1997
12. Crowe MJ, Shuman SL, Masters JN, et al: Morphological evidence suggesting apoptotic nuclei in spinal cord injury. Soc Neurosci Abstr 21:232, 1995 (Abstract)
13. Dusart I, Schwab ME: Secondary cell death and the inflammatory reaction after dorsal hemisection of the rat spinal cord. Eur J Neurosci 6:712-724, 1994
14. Duvall E, Wyllie AH, Morris RG: Macrophage recognition of cells undergoing programmed cell death (apoptosis). Immunology 56:351-358, 1985
15. Ellis RE, Yvan J, Horvitz HR: Mechanisms and functions of cell death. Annu Rev Cell Biol 7:663-698, 1991
16. Enari M, Talanian RV, Wong WW. et al: Sequential activation of ICE-like and CPP32-like proteases during Fas-mediated apoptosis. Nature 380:723-726, 1996 (Letter)
17. Fraser A, Evan G: A license to kill. Cell 85:781-784, 1996
18. Furukawa K, Estus S, Fu WM, et al: Neuroprotective action of cycloheximide involves induction of Bcl-2 and antioxidant pathways. J Cell Biol 136:1137-1149, 1997
19. Gavrieli Y, Sherman Y, Ben-Sasson SA: Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J Cell Biol 119:493-501, 1992
20. Gehrmann J, Banati RB: Microglial turnover in the injured CNS: activated microglia undergo delayed DNA fragmentation following peripheral nerve injury. J Neuropathol Exp Neurol 54:680-688, 1995
21. Hall ED, Yonkers PA, Andrus PK, et al: Biochemistry and pharmacology of lipid antioxidants in acute brain and spinal cord injury. J Neurotrauma 9 (Suppl):S425-S442, 1992
22. Hamburger V: Cell death in the development of the lateral motor column of the chick embryo. J Comp Neurol 160: 535-546, 1975
23. Hansebout RR, Blight AR, Fawcett S, et al: 4-Aminopyridine in chronic spinal cord injury: a controlled, double-blind, crossover study in eight patients. J Neurotrauma 10:1-18, 1993
24. Hara H, Friedlander RM, Gagliardini V, et al: Inhibition of interleukin 1β converting enzyme family proteases reduce ischemic and excitotoxic neuronal damage. Proc Natl Acad Sci USA 94:2007-2012, 1997
25. Henderson CE: Programmed cell death in the developing nervous system. Neuron 17:579-585, 1997
26. Hisahara S, Shoji S, Okano H, et al: ICE/CED-3 family executes oligodendrocyte apoptosis by tumor necrosis factor. J Neurochem 69:10-20, 1997
27. Hockenberry D: Defining apoptosis. Am J Pathol 146:16-19, 1995
28. Hockenberry DM, Oltvai ZN, Yin XM, et al: Bcl-2 functions in an antioxidant pathway to prevent apoptosis. Cell 75:241-251, 1993
29. Horwitz HR, Ellis HM, Sternberg DW: Programmed cell death in nematode development. Neurosci Comment 1:56-65, 1982
30. Jänicke RU, Sprengart ML, Wati MR, et al: Caspase-3 is required for DNA fragmentation and morphological changes associated with apoptosis. J Biol Chem 273:9357-9360, 1997
31. Kane AB: Redefining cell death. Am J Pathol 146:1-2, 1995
32. Katoh K, Ikata T, Katoh S, et al: Induction and its spread of apoptosis in rat spinal cord after mechanical trauma. Neurosci Lett 216:9-12, 1996
33. Keane RW, Srinivasan A, Foster LM, et al: Activation of CPP32 during apoptosis of neurons and astrocytes. J Neurosci Res 48:168-180, 1997
34. Kuida K, Zheng TS, Na S, et al: Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice. Nature 384:368-372, 1996
35. Li GI, Brodin G, Farooque M, et al: Apoptosis and expression of Bcl-2 after compression trauma to rat spinal cord. J Neuropathol Exp Neurol 55:280-289, 1996
36. Liu XZ, Xu XM, Hu R, et al: Neuronal and glial apoptosis after traumatic spinal cord injury. J Neurosci 17:5395-5406, 1997
37. Majno G, Joris I: Apoptosis, oncosis, and necrosis. An overview of cell death. Am J Pathol 146:3-15, 1995
38. Martin SJ, Green DR: Protease activation during apoptosis: death by a thousand cuts. Cell 82:349-352, 1995
39. Milligan CE, Prevette D, Yaginuma H, et al: Peptide inhibitors of the ICE protease family arrest programmed cell death of motoneurons in vivo and in vitro. Neuron 15:385-393, 1995
40. Nagata S: Apoptosis by death factor. Cell 88:355-365, 1997
41. Namura S, Zhu J, Fink K, et al: Activation and cleavage of caspase-3 in apoptosis induced by experimental cerebral ischemia. J Neurosci 18:3659-3668, 1998
42. Nguyen KB, McCombe PA, Pender MP: Macrophage apoptosis in the central nervous system in experimental autoimmune encephalomyelitis. J Autoimmun 17:145-152, 1994
43. Nicotera P, Ankarcrona M, Bonfoco E, et al: Neuronal necrosis and apoptosis: two distinct events induced by exposure to glutamate or oxidative stress. Adv Neurol 72:95-101, 1997
44. Pender MP, Nguyen KB, McCombe PA, et al: Apoptosis in the nervous system in experimental allergic encephalomyelitis. J Neurol Sci 104:81-87, 1991
45. Prineas JW, Kwon EE, Goldenberg PZ, et al: Multiple sclerosis. Oligodendrocyte proliferation and differentiation in fresh lesions. Lab Invest 61:489-503, 1989
46. Rink A, Fung KM, Trojanowski JQ, et al: Evidence of apoptotic cell death after experimental traumatic brain injury in the rat. Am J Pathol 147:1575-1583, 1995
47. Savitz SI, Rosenbaum DM: Apoptosis in neurological disease. Neurosurgery 42:555-574, 1998
48. Shuman SL, Bresnahan JC, Beattie NS: Apoptosis of microglia and oligodendrocytes after spinal cord injury in rats. J Neurosci Res 50:798-808, 1997
49. Tator CH, Fehlings MG: Review of the secondary injury theory of acute spinal cord trauma with emphasis on vascular mechanisms. J Neurosurg 75:15-26, 1991
50. Thompson CB: Apoptosis in the pathogenesis and treatment of disease. Science 267:1456-1462, 1995
51. Vela JM, Dalmau I, Gonzáles B, et al: The microglial reaction in spinal cords of jimpy mice is related to apoptotic oligodendrocytes. Brain Res 712:134-142, 1996
52. Weedon D, Searle J, Kerr JF: Apoptosis. Its nature and implications for dermatopathology. Am J Dermatopathol 1: 133-144, 1979
53. Wood PL: Microglia as a unique cellular target in the treatment of stroke: potential neurotoxic mediators produced by activated microglia. Neurol Res 17:242-248, 1995
54. Yakovlev AG, Knoblach SM, Fan L, et al: Activation of CPP32-like caspases contributes to neuronal apoptosis and neurological dysfunction after traumatic brain injury. J Neurosci 17:7415-7424, 1997
55. Young W: Secondary injury mechanisms in acute spinal cord injury. J Emerg Med 11 (Suppl 1):13-22, 1993