Calpain inhibitor inhibits p35-p25-Cdk5 activation, decreases tau hyperphosphorylation, and improves neurological function after spinal cord hemisection in rats

Journal of Neuropathology and Experimental Neurology

Volumn 64, Issue 1, 2005, Pages 15-26

  Hung, Kuo Sheng ^a   Hwang, Shiuh Lin ^b   Liang, Chung Ling ^c   Chen, Yann Jang ^d   Lee, Tsung Hsing ^a   Liu, Jong Kang ^e   Howng, Shen Long ^b   Wang, Cheng Haung ^a  

^a CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

^b KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^c Kaohsiung Municipal United Hospital   (Taiwan)

^d NATIONAL YANG MING UNIVERSITY   (Taiwan)

^e NATIONAL SUN YAT SEN UNIVERSITY   (Taiwan)

Author keywords

Apoptosis; Calpain inhibitor; Hemisection; p35; Spinal cord injury; Tau

Indexed keywords

CALPAIN; CALPASTATIN; CYCLIN DEPENDENT KINASE 5; DIMETHYL SULFOXIDE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P25; PROTEIN P35; [1 [(1 FORMYL 2 PHENYLETHYL)CARBAMOYL] 2 METHYLPROPYL]CARBAMIC ACID BENZYL ESTER;

ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; ASTROCYTOSIS; CELL MEMBRANE PERMEABILITY; CONTROLLED STUDY; ENZYME ACTIVATION; MALE; NERVE CELL NECROSIS; NERVE DEGENERATION; NEUROFIBRILLARY TANGLE; NEUROLOGIC DISEASE; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPINAL CORD HEMISECTION; SPINAL CORD INJURY; UPREGULATION;

EID: 13244296826     PISSN: 00223069     EISSN: None     Source Type: Journal    
DOI: 10.1093/jnen/64.1.15     Document Type: Article

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