Decoy peptides that bind dynorphin noncovalently prevent NMDA receptor-mediated neurotoxicity

Journal of Proteome Research

Volumn 5, Issue 4, 2006, Pages 1017-1023

  Woods, Amina S ^a,g   Kaminski, Rafal ^a   Oz, Murat ^a   Wang, Yun ^a   Hauser, Kurt ^b   Goody, Robin ^b   Wang, Hay Yan J ^a   Jackson, Shelley N ^a   Zeitz, Peter ^c   Zeitz, Karla P ^c   Zolkowska, Dorota ^a   Schepers, Raf ^a   Nold, Michael ^d   Danielson, Jens ^e   Gräslund, Astrid ^e   Vukojevic, Vladana ^f   Balkalkin, Georgy ^f   Basbaum, Alan ^c   Shippenberg, Toni ^a  

^a NATIONAL INSTITUTE ON DRUG ABUSE   (United States)

^b UNIVERSITY OF KENTUCKY   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d WATERS CORPORATION   (United States)

^e STOCKHOLM UNIVERSITY   (Sweden)

^f KAROLINSKA INSTITUTE   (Sweden)

^g NONE   (United States)

Author keywords

Dynorphin; Neurotoxicity; NMDA receptor; Noncovalent interaction; Paralysis

Indexed keywords

DECOY PEPTIDE; DYNORPHIN; DYNORPHIN A; DYNORPHIN DERIVATIVE; DYNORPHIN[2-17]; EPITOPE; LYSYLVALYLASPARAGINYLSERYLGLUTAMYLGLUTAMYLGLUTAMYLGLUTAMYLGLUTAMYLASPARTYLA LANINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 1; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; OPIATE ANTAGONIST; PEPTIDE; PRODYNORPHIN; SYNTHETIC PEPTIDE; UNCLASSIFIED DRUG;

ALLODYNIA; ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DEATH; COMPLEX FORMATION; FETUS; MALE; MEMBRANE CURRENT; MOUSE; NEUROLOGIC DISEASE; NEUROPROTECTION; NEUROTOXICITY; NONCOVALENT INTERACTION; NONHUMAN; PARALYSIS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN INTERACTION; RECEPTOR BINDING; SPINAL CORD; SPINAL CORD INJURY;

AMINO ACID SEQUENCE; ANIMALS; APOPTOSIS; BEHAVIOR, ANIMAL; CELLS, CULTURED; CONSERVED SEQUENCE; DYNORPHINS; ELECTROPHYSIOLOGY; FEMALE; GANGLIA, SPINAL; IMMUNOHISTOCHEMISTRY; MALE; MICE; MICE, INBRED ICR; MICROINJECTIONS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NEUROPROTECTIVE AGENTS; NEUROTOXICITY SYNDROMES; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; OOCYTES; PARALYSIS; PEPTIDES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, N-METHYL-D-ASPARTATE; RNA, MESSENGER; SPINAL CORD; TIME FACTORS; XENOPUS;

ANIMALIA;

EID: 33645760177     PISSN: 15353893     EISSN: None     Source Type: Journal    
DOI: 10.1021/pr060016+     Document Type: Article

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