Methylprednisolone for acute spinal cord injury: 5-Year practice reversal

Canadian Journal of Neurological Sciences

Volumn 35, Issue 1, 2008, Pages 41-45

  Hurlbert, R John ^a,b   Hamilton, Mark G ^a  

^a UNIVERSITY OF CALGARY   (Canada)

^b FOOTHILLS HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

DEXAMETHASONE; METHYLPREDNISOLONE; STEROID;

ACUTE DISEASE; ARTICLE; CONTROLLED STUDY; HEALTH SURVEY; HUMAN; HUMAN EXPERIMENT; LAW SUIT; MEDICAL PRACTICE; NORMAL HUMAN; PRESCRIPTION; PRIORITY JOURNAL; SPINAL CORD INJURY; STRUCTURED QUESTIONNAIRE; SURGEON;

EID: 42049104347     PISSN: 03171671     EISSN: None     Source Type: Journal    
DOI: 10.1017/S031716710000754X     Document Type: Article

References (22)

1. Bracken MB, Shepard MJ, Collins WF, Holford, TR, Young W, Baskin D, et al. A randomized, controlled trial of methylprednisolone or naloxone in the treatment of acute spinal-cord injury: results of the second national acute spinal cord injury study. N Engl J Med. 1990;322:1405-11.
2. Bracken MB, Shepard MJ, Collins WF, Holford TR, Baskin D, Eisenberg HM, et al. Methylprednisolone or naloxone treatment after acute spinal cord injury: 1-year follow-up data. J Neurosurg. 1992;76:23-31.
3. Bracken MB, Shepard MJ, Holford TR, Seo-Summers L, Aldrich EF, Fazl M, et al. Administration of methylprednisolone for 24 or 48 hours or tirilazad mesylate for 48 hours in the treatment of acute spinal cord injury. JAMA. 1997;277:1597-1604.
4. Bracken MB, Shepard MJ, Holford TR, Leo-Summers L, Aldrich EF, Fazl M, et al. Methylprednisolone or tirilazad mesylate administration after acute spinal cord injury: 1-year follow-up. J Neurosurg. 1998; 89:699-706.
5. Nesathurai S. Steroids and spinal cord injury: revisiting the NASCIS 2 and NASCIS 3 trials. J Trauma. 1998;45:1088-93.
6. Coleman WP, Benzel E, Cahill DW, Ducker T, Geisler F, Green B, et al. A critical appraisal of the reporting of the National Acute Spinal Cord Injury Studies (II and III) of methylprednisolone in acute spinal cord injury. J Spinal Disord. 2000; 13(3):185-99.
7. Hurlbert RJ. Methylprednisolone for acute spinal cord injury: an inappropriate standard of care. J Neurosurg. 2000;93:1-7.
8. Short DJ, El Masry WS, Jones PW. High dose methylprednisolone in the management of acute spinal cord injury: a systematic review from a clinical perspective. Spinal Cord. 2000;38:273-86.
9. Hurlbert RJ. The role of steroids in acute spinal cord injury: an evidence-based analysis. Spine. 2001;26(24S):S39-46.
10. Hurlbert RJ, Moulton R. Why do you prescribe methylprednisolone for acute spinal cord injury? Can J Neurol Sci. 2002;29:236-9.
11. Hugenholtz H, Cass DE, Dvorak MF, Fewer DH, Fox RJ, Izukawa DM, et al. High-dose methylprednisolone for acute closed spinal cord injury: only a treatment option. Can J Neurol Sci. 2002;29:227-35.
12. Hadley MN, Walters BC, Grabb PA, Oyesiku NM, Przybylski GJ, Resnick DK, et al. Pharmacological therapy after acute spinal cord injury. Neurosurgery. 2002;50Suppl:63-72.
13. Bledsoe BE, Wesley AK, Salomone P. High-dose steroids for acute spinal cord injury in emergency medical services. Prehosp Emerg Care. 2004;8(3):313-16.
14. Pollard DE, Apple DF. Factors associated with improved neurological outcomes in patients with incomplete tetraplegia [clinical case series]. Spine. 2003;28(1):33-8.
15. Qian T, Guo X, Levi AD, Vanni S, Shebert RT, Sipski ML. High-dose methylprednisolone may cause myopathy in acute spinal cord injury patients. Spinal Cord. 2005;43:199-203.
16. Aito S, D'Andrea M, Werhagen L. Spinal cord injuries due to diving accidents. Spinal Cord. 2005;43(2):109-16.
17. Hurlbert RJ. Strategies of medical intervention in the management of acute spinal cord injury. Spine. 2006;31(11):516-21.
18. Sayer FT, Kronvall E, Nilsson OG. Methylprednisolone treatment in acute spinal cord injury: the myth challenged through a structured review of the literature. Spine. 2006;6: 335-43.
19. Leypold BG, Flanders AE, Schwartz ED, Burns AS. The impact of methylprednisolone on lesion severity following spinal cord injury. Spine. 2007;32(3):373-78.
20. Bracken MB. Pharmacological interventions for acute spinal cord injury. Cochrane Database of Systematic Reviews (2): CD001046, 2000.
21. Bracken MB. Steroids for acute spinal cord injury (update). Cochrane Database of Systematic Reviews (3):CD001046, 2002.
22. Bracken MB. Steroids for acute spinal cord injury (update). Cochrane Database of Systematic Reviews (2):CD001046, 2007.