-
1
-
-
68949145931
-
Apoptotic cells promote their own clearance and immune tolerance through activation of the nuclear receptor LXR
-
N. A-Gonzalez, S.J. Bensinger, C. Hong, S. Beceiro, M.N. Bradley, N. Zelcer, J. Deniz, C. Ramirez, M. Diaz, G. Gallardo, C.R. de Galarreta, J. Salazar, F. Lopez, P. Edwards, J. Parks, M. Andujar, P. Tontonoz, and A. Castrillo Apoptotic cells promote their own clearance and immune tolerance through activation of the nuclear receptor LXR Immunity 31 2009 245 258
-
(2009)
Immunity
, vol.31
, pp. 245-258
-
-
A-Gonzalez, N.1
Bensinger, S.J.2
Hong, C.3
Beceiro, S.4
Bradley, M.N.5
Zelcer, N.6
Deniz, J.7
Ramirez, C.8
Diaz, M.9
Gallardo, G.10
De Galarreta, C.R.11
Salazar, J.12
Lopez, F.13
Edwards, P.14
Parks, J.15
Andujar, M.16
Tontonoz, P.17
Castrillo, A.18
-
2
-
-
0030939116
-
Human acetyl-CoA carboxylase 2. Molecular cloning, characterization, chromosomal mapping, and evidence for two isoforms
-
L. Abu-Elheiga, D.B. Almarza-Ortega, A. Baldini, and S.J. Wakil Human acetyl-CoA carboxylase 2. Molecular cloning, characterization, chromosomal mapping, and evidence for two isoforms J. Biol. Chem. 272 1997 10669 10677
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 10669-10677
-
-
Abu-Elheiga, L.1
Almarza-Ortega, D.B.2
Baldini, A.3
Wakil, S.J.4
-
3
-
-
0034652297
-
The subcellular localization of acetyl-CoA carboxylase 2
-
DOI 10.1073/pnas.97.4.1444
-
L. Abu-Elheiga, W.R. Brinkley, L. Zhong, S.S. Chirala, G. Woldegiorgis, and S.J. Wakil The subcellular localization of acetyl-CoA carboxylase 2 Proc. Natl. Acad. Sci. U.S.A. 97 2000 1444 1449 (Pubitemid 30118460)
-
(2000)
Proceedings of the National Academy of Sciences of the United States of America
, vol.97
, Issue.4
, pp. 1444-1449
-
-
Abu-Elheiga, L.1
Brinkley, W.R.2
Zhong, L.3
Chirala, S.S.4
Woldegiorgis, G.5
Wakil, S.J.6
-
4
-
-
0029041316
-
Human acetyl-CoA carboxylase: Characterization, molecular cloning, and evidence for two isoforms
-
L. Abu-Elheiga, A. Jayakumar, A. Baldini, S.S. Chirala, and S.J. Wakil Human acetyl-CoA carboxylase: characterization, molecular cloning, and evidence for two isoforms Proc. Natl. Acad. Sci. U.S.A. 92 1995 4011 4015
-
(1995)
Proc. Natl. Acad. Sci. U.S.A.
, vol.92
, pp. 4011-4015
-
-
Abu-Elheiga, L.1
Jayakumar, A.2
Baldini, A.3
Chirala, S.S.4
Wakil, S.J.5
-
5
-
-
0035970805
-
Continuous fatty acid oxidation and reduced fat storage in mice lacking acetyl-coa carboxylase 2
-
DOI 10.1126/science.1056843
-
L. Abu-Elheiga, M.M. Matzuk, K.A. Abo-Hashema, and S.J. Wakil Continuous fatty acid oxidation and reduced fat storage in mice lacking acetyl-CoA carboxylase 2 Science 291 2001 2613 2616 (Pubitemid 32249687)
-
(2001)
Science
, vol.291
, Issue.5513
, pp. 2613-2616
-
-
Abu-Elheiga, L.1
Matzuk, M.M.2
Abo-Hashema, K.A.H.3
Wakil, S.J.4
-
6
-
-
24744448667
-
Mutant mice lacking acetyl-CoA carboxylase 1 are embryonically lethal
-
DOI 10.1073/pnas.0505714102
-
L. Abu-Elheiga, M.M. Matzuk, P. Kordari, W. Oh, T. Shaikenov, Z. Gu, and S.J. Wakil Mutant mice lacking acetyl-CoA carboxylase 1 are embryonically lethal Proc. Natl. Acad. Sci. U.S.A. 102 2005 12011 12016 (Pubitemid 41291120)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.34
, pp. 12011-12016
-
-
Abu-Elheiga, L.1
Matzuk, M.M.2
Kordari, P.3
Oh, W.4
Shaikenov, T.5
Gu, Z.6
Wakil, S.J.7
-
7
-
-
0042337449
-
Acetyl-CoA carboxylase 2 mutant mice are protected against obesity and diabetes induced by high-fat/high-carbohydrate diets
-
DOI 10.1073/pnas.1733877100
-
L. Abu-Elheiga, W. Oh, P. Kordari, and S.J. Wakil Acetyl-CoA carboxylase 2 mutant mice are protected against obesity and diabetes induced by high-fat/high-carbohydrate diets Proc. Natl. Acad. Sci. U.S.A. 100 2003 10207 10212 (Pubitemid 37071857)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.18
, pp. 10207-10212
-
-
Abu-Elheiga, L.1
Oh, W.2
Kordari, P.3
Wakil, S.J.4
-
8
-
-
33748182901
-
Genetic variability at the LXR gene (NR1H2) may contribute to the risk of Alzheimer's disease
-
DOI 10.1016/j.neurobiolaging.2005.08.010, PII S0197458005002393
-
O. Adighibe, S. Arepalli, J. Duckworth, J. Hardy, and F. Wavrant-De Vrieze Genetic variability at the LXR gene (NR1H2) may contribute to the risk of Alzheimer's disease Neurobiol. Aging 27 2006 1431 1434 (Pubitemid 44313874)
-
(2006)
Neurobiology of Aging
, vol.27
, Issue.10
, pp. 1431-1434
-
-
Adighibe, O.1
Arepalli, S.2
Duckworth, J.3
Hardy, J.4
Wavrant-De Vrieze, F.5
-
9
-
-
33646145315
-
Functional characterization of human 1-acylglycerol-3-phosphate acyltransferase isoform 8: Cloning, tissue distribution, gene structure, and enzymatic activity
-
A.K. Agarwal, R.I. Barnes, and A. Garg Functional characterization of human 1-acylglycerol-3-phosphate acyltransferase isoform 8: cloning, tissue distribution, gene structure, and enzymatic activity Arch. Biochem. Biophys. 449 2006 64 76
-
(2006)
Arch. Biochem. Biophys.
, vol.449
, pp. 64-76
-
-
Agarwal, A.K.1
Barnes, R.I.2
Garg, A.3
-
10
-
-
34447104351
-
Functional characterization of human 1-acylglycerol-3-phosphate-O- acyltransferase isoform 9: Cloning, tissue distribution, gene structure, and enzymatic activity
-
DOI 10.1677/JOE-07-0027
-
A.K. Agarwal, S. Sukumaran, R. Bartz, R.I. Barnes, and A. Garg Functional characterization of human 1-acylglycerol-3-phosphate-O-acyltransferase isoform 9: cloning, tissue distribution, gene structure, and enzymatic activity J. Endocrinol. 193 2007 445 457 (Pubitemid 47028695)
-
(2007)
Journal of Endocrinology
, vol.193
, Issue.3
, pp. 445-457
-
-
Agarwal, A.K.1
Sukumaran, S.2
Bartz, R.3
Barnes, R.I.4
Garg, A.5
-
11
-
-
1842584446
-
Do polyunsaturated fatty acids ameliorate hepatic steatosis in obese mice by SREPB-1 suppression or by correcting essential fatty acid deficiency
-
author reply 1177-1178
-
I.P. Alwayn, P.J. Javid, K.M. Gura, V. Nose, M. Ollero, and M. Puder Do polyunsaturated fatty acids ameliorate hepatic steatosis in obese mice by SREPB-1 suppression or by correcting essential fatty acid deficiency Hepatology 39 2004 1176 1177 author reply 1177-1178
-
(2004)
Hepatology
, vol.39
, pp. 1176-1177
-
-
Alwayn, I.P.1
Javid, P.J.2
Gura, K.M.3
Nose, V.4
Ollero, M.5
Puder, M.6
-
12
-
-
0030747895
-
Tissue distribution and quantification of the expression of mRNAs of peroxisome proliferator-activated receptors and liver X receptor-α in humans: No alteration in adipose tissue of obese and NIDDM patients
-
D. Auboeuf, J. Rieusset, L. Fajas, P. Vallier, V. Frering, J.P. Riou, B. Staels, J. Auwerx, M. Laville, and H. Vidal Tissue distribution and quantification of the expression of mRNAs of peroxisome proliferator-activated receptors and liver X receptor-alpha in humans: no alteration in adipose tissue of obese and NIDDM patients Diabetes 46 1997 1319 1327 (Pubitemid 27315281)
-
(1997)
Diabetes
, vol.46
, Issue.8
, pp. 1319-1327
-
-
Auboeuf, D.1
Rieusset, J.2
Fajas, L.3
Vallier, P.4
Frering, V.5
Riou, J.P.6
Staels, B.7
Auwerx, J.8
Laville, M.9
Vidal, H.10
-
13
-
-
79151476474
-
Sulfation of 25-hydroxycholesterol by SULT2B1b decreases cellular lipids via the LXR/SREBP-1c signaling pathway in human aortic endothelial cells
-
Q. Bai, L. Xu, G. Kakiyama, M.A. Runge-Morris, P.B. Hylemon, L. Yin, W.M. Pandak, and S. Ren Sulfation of 25-hydroxycholesterol by SULT2B1b decreases cellular lipids via the LXR/SREBP-1c signaling pathway in human aortic endothelial cells Atherosclerosis 214 2010 350 356
-
(2010)
Atherosclerosis
, vol.214
, pp. 350-356
-
-
Bai, Q.1
Xu, L.2
Kakiyama, G.3
Runge-Morris, M.A.4
Hylemon, P.B.5
Yin, L.6
Pandak, W.M.7
Ren, S.8
-
14
-
-
46149098344
-
LXR signaling couples sterol metabolism to proliferation in the acquired immune response
-
DOI 10.1016/j.cell.2008.04.052, PII S0092867408006946
-
S.J. Bensinger, M.N. Bradley, S.B. Joseph, N. Zelcer, E.M. Janssen, M.A. Hausner, R. Shih, J.S. Parks, P.A. Edwards, B.D. Jamieson, and P. Tontonoz LXR signaling couples sterol metabolism to proliferation in the acquired immune response Cell 134 2008 97 111 (Pubitemid 351905740)
-
(2008)
Cell
, vol.134
, Issue.1
, pp. 97-111
-
-
Bensinger, S.J.1
Bradley, M.N.2
Joseph, S.B.3
Zelcer, N.4
Janssen, E.M.5
Hausner, M.A.6
Shih, R.7
Parks, J.S.8
Edwards, P.A.9
Jamieson, B.D.10
Tontonoz, P.11
-
15
-
-
78649944880
-
Identification of 5alpha, 6alpha-epoxycholesterol as a novel modulator of liver X receptor activity
-
T.J. Berrodin, Q. Shen, E.M. Quinet, M.R. Yudt, L.P. Freedman, and S. Nagpal Identification of 5alpha, 6alpha-epoxycholesterol as a novel modulator of liver X receptor activity Mol. Pharmacol. 78 2010 1046 1058
-
(2010)
Mol. Pharmacol.
, vol.78
, pp. 1046-1058
-
-
Berrodin, T.J.1
Shen, Q.2
Quinet, E.M.3
Yudt, M.R.4
Freedman, L.P.5
Nagpal, S.6
-
16
-
-
34247139296
-
Selective up-regulation of LXR-regulated genes ABCA1, ABCG1, and APOE in macrophages through increased endogenous synthesis of 24(S),25-epoxycholesterol
-
DOI 10.1074/jbc.M611063200
-
M.M. Beyea, C.L. Heslop, C.G. Sawyez, J.Y. Edwards, J.G. Markle, R.A. Hegele, and M.W. Huff Selective up-regulation of LXR-regulated genes ABCA1, ABCG1, and APOE in macrophages through increased endogenous synthesis of 24(S),25-epoxycholesterol J. Biol. Chem. 282 2007 5207 5216 (Pubitemid 47093759)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.8
, pp. 5207-5216
-
-
Beyea, M.M.1
Heslop, C.L.2
Sawyez, C.G.3
Edwards, J.Y.4
Markle, J.G.5
Hegele, R.A.6
Huff, M.W.7
-
17
-
-
0037323903
-
Regulation of cell survival and proliferation by the FOXO (Forkhead box, class O) subfamily of Forkhead transcription factors
-
K.U. Birkenkamp, and P.J. Coffer Regulation of cell survival and proliferation by the FOXO (Forkhead box, class O) subfamily of Forkhead transcription factors Biochem. Soc. Trans. 31 2003 292 297 (Pubitemid 36241447)
-
(2003)
Biochemical Society Transactions
, vol.31
, Issue.1
, pp. 292-297
-
-
Birkenkamp, K.U.1
Coffer, P.J.2
-
18
-
-
33947706821
-
Rediscovery of cerebrosterol
-
DOI 10.1007/s11745-006-1003-2
-
I. Bjorkhem Rediscovery of cerebrosterol Lipids 42 2007 5 14 (Pubitemid 46490739)
-
(2007)
Lipids
, vol.42
, Issue.1
, pp. 5-14
-
-
Bjorkhem, I.1
-
19
-
-
0026438895
-
Preferential cyclization of 2,3(S):22(S),23-dioxidosqualene by mammalian 2,3-oxidosqualene-lanosterol cyclase
-
O. Boutaud, D. Dolis, and F. Schuber Preferential cyclization of 2,3(S):22(S),23-dioxidosqualene by mammalian 2,3-oxidosqualene-lanosterol cyclase Biochem. Biophys. Res. Commun. 188 1992 898 904
-
(1992)
Biochem. Biophys. Res. Commun.
, vol.188
, pp. 898-904
-
-
Boutaud, O.1
Dolis, D.2
Schuber, F.3
-
20
-
-
0036716912
-
The small heterodimer partner interacts with the liver X receptor α and represses its transcriptional activity
-
DOI 10.1210/me.2001-0194
-
C. Brendel, K. Schoonjans, O.A. Botrugno, E. Treuter, and J. Auwerx The small heterodimer partner interacts with the liver X receptor alpha and represses its transcriptional activity Mol. Endocrinol. 16 2002 2065 2076 (Pubitemid 35013455)
-
(2002)
Molecular Endocrinology
, vol.16
, Issue.9
, pp. 2065-2076
-
-
Brendel, C.1
Schoonjans, K.2
Botrugno, O.A.3
Treuter, E.4
Auwerx, J.5
-
21
-
-
78649855297
-
Salt-inducible kinase 2 links transcriptional coactivator p300 phosphorylation to the prevention of ChREBP-dependent hepatic steatosis in mice
-
J. Bricambert, J. Miranda, F. Benhamed, J. Girard, C. Postic, and R. Dentin Salt-inducible kinase 2 links transcriptional coactivator p300 phosphorylation to the prevention of ChREBP-dependent hepatic steatosis in mice J. Clin. Invest. 120 2010 4316 4331
-
(2010)
J. Clin. Invest.
, vol.120
, pp. 4316-4331
-
-
Bricambert, J.1
Miranda, J.2
Benhamed, F.3
Girard, J.4
Postic, C.5
Dentin, R.6
-
22
-
-
67349268463
-
Oxysterols: Sources, cellular storage and metabolism, and new insights into their roles in cholesterol homeostasis
-
A.J. Brown, and W. Jessup Oxysterols: sources, cellular storage and metabolism, and new insights into their roles in cholesterol homeostasis Mol. Aspects Med. 30 2009 111 122
-
(2009)
Mol. Aspects Med.
, vol.30
, pp. 111-122
-
-
Brown, A.J.1
Jessup, W.2
-
23
-
-
69249136669
-
Working towards an exegesis for lipids in biology
-
H.A. Brown, and R.C. Murphy Working towards an exegesis for lipids in biology Nat. Chem. Biol. 5 2009 602 606
-
(2009)
Nat. Chem. Biol.
, vol.5
, pp. 602-606
-
-
Brown, H.A.1
Murphy, R.C.2
-
24
-
-
66349134748
-
Cholesterol feedback: From Schoenheimer's bottle to Scap's MELADL
-
M.S. Brown, and J.L. Goldstein Cholesterol feedback: from Schoenheimer's bottle to Scap's MELADL J. Lipid Res. 50 Suppl. 2009 S15 S27
-
(2009)
J. Lipid Res.
, vol.50
, Issue.SUPPL.
-
-
Brown, M.S.1
Goldstein, J.L.2
-
25
-
-
77955129487
-
Liver X receptor signaling pathways and atherosclerosis
-
A.C. Calkin, and P. Tontonoz Liver X receptor signaling pathways and atherosclerosis Arterioscler. Thromb. Vasc. Biol. 30 2010 1513 1518
-
(2010)
Arterioscler. Thromb. Vasc. Biol.
, vol.30
, pp. 1513-1518
-
-
Calkin, A.C.1
Tontonoz, P.2
-
26
-
-
51549107903
-
Identification of a lipokine, a lipid hormone linking adipose tissue to systemic metabolism
-
H. Cao, K. Gerhold, J.R. Mayers, M.M. Wiest, S.M. Watkins, and G.S. Hotamisligil Identification of a lipokine, a lipid hormone linking adipose tissue to systemic metabolism Cell 134 2008 933 944
-
(2008)
Cell
, vol.134
, pp. 933-944
-
-
Cao, H.1
Gerhold, K.2
Mayers, J.R.3
Wiest, M.M.4
Watkins, S.M.5
Hotamisligil, G.S.6
-
27
-
-
33947104623
-
Catalytic properties of MGAT3, a putative triacylgycerol synthase
-
DOI 10.1194/jlr.M600331-JLR200
-
J. Cao, L. Cheng, and Y. Shi Catalytic properties of MGAT3, a putative triacylgycerol synthase J. Lipid Res. 48 2007 583 591 (Pubitemid 46397461)
-
(2007)
Journal of Lipid Research
, vol.48
, Issue.3
, pp. 583-591
-
-
Cao, J.1
Cheng, L.2
Shi, Y.3
-
28
-
-
33845941190
-
Molecular identification of microsomal acyl-CoA:glycerol-3-phosphate acyltransferase, a key enzyme in de novo triacylglycerol synthesis
-
DOI 10.1073/pnas.0609140103
-
J. Cao, J.L. Li, D. Li, J.F. Tobin, and R.E. Gimeno Molecular identification of microsomal acyl-CoA:glycerol-3-phosphate acyltransferase, a key enzyme in de novo triacylglycerol synthesis Proc. Natl. Acad. Sci. U.S.A. 103 2006 19695 19700 (Pubitemid 46037494)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.52
, pp. 19695-19700
-
-
Cao, J.1
Li, J.-A.2
Li, D.3
Tobin, J.F.4
Gimeno, R.E.5
-
29
-
-
59149106049
-
Phosphatidic acid phosphatase, a key enzyme in the regulation of lipid synthesis
-
G.M. Carman, and G.S. Han Phosphatidic acid phosphatase, a key enzyme in the regulation of lipid synthesis J. Biol. Chem. 284 2009 2593 2597
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 2593-2597
-
-
Carman, G.M.1
Han, G.S.2
-
30
-
-
13144281703
-
Identification of a gene encoding an acyl CoA:diacylglycerol acyltransferase, a key enzyme in triacylglycerol synthesis
-
DOI 10.1073/pnas.95.22.13018
-
S. Cases, S.J. Smith, Y.W. Zheng, H.M. Myers, S.R. Lear, E. Sande, S. Novak, C. Collins, C.B. Welch, A.J. Lusis, S.K. Erickson, and R.V. Farese Jr. Identification of a gene encoding an acyl CoA:diacylglycerol acyltransferase, a key enzyme in triacylglycerol synthesis Proc. Natl. Acad. Sci. U.S.A. 95 1998 13018 13023 (Pubitemid 28509516)
-
(1998)
Proceedings of the National Academy of Sciences of the United States of America
, vol.95
, Issue.22
, pp. 13018-13023
-
-
Cases, S.1
Smith, S.J.2
Zheng, Y.-W.3
Myers, H.M.4
Lear, S.R.5
Sande, E.6
Novak, S.7
Collins, C.8
Welch, C.B.9
Lusis, A.J.10
Erickson, S.K.11
Farese Jr., R.V.12
-
31
-
-
0035914356
-
Cloning of DGAT2, a second mammalian diacylglycerol acyltransferase, and related family members
-
S. Cases, S.J. Stone, P. Zhou, E. Yen, B. Tow, K.D. Lardizabal, T. Voelker, and R.V. Farese Jr. Cloning of DGAT2, a second mammalian diacylglycerol acyltransferase, and related family members J. Biol. Chem. 276 2001 38870 38876
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 38870-38876
-
-
Cases, S.1
Stone, S.J.2
Zhou, P.3
Yen, E.4
Tow, B.5
Lardizabal, K.D.6
Voelker, T.7
Farese, Jr.R.V.8
-
32
-
-
33847006599
-
The Liver X Receptor (LXR) and hepatic lipogenesis: The carbohydrate-response element-binding protein is a target gene of LXR
-
DOI 10.1074/jbc.M605023200
-
J.Y. Cha, and J.J. Repa The liver X receptor (LXR) and hepatic lipogenesis. The carbohydrate-response element-binding protein is a target gene of LXR J. Biol. Chem. 282 2007 743 751 (Pubitemid 47076632)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.1
, pp. 743-751
-
-
Cha, J.-Y.1
Repa, J.J.2
-
33
-
-
68149098866
-
Identification of a physiologically relevant endogenous ligand for PPARalpha in liver
-
M.V. Chakravarthy, I.J. Lodhi, L. Yin, R.R. Malapaka, H.E. Xu, J. Turk, and C.F. Semenkovich Identification of a physiologically relevant endogenous ligand for PPARalpha in liver Cell 138 2009 476 488
-
(2009)
Cell
, vol.138
, pp. 476-488
-
-
Chakravarthy, M.V.1
Lodhi, I.J.2
Yin, L.3
Malapaka, R.R.4
Xu, H.E.5
Turk, J.6
Semenkovich, C.F.7
-
34
-
-
22544480378
-
"New" hepatic fat activates PPARα to maintain glucose, lipid, and cholesterol homeostasis
-
DOI 10.1016/j.cmet.2005.04.002, PII S1550413105001105
-
M.V. Chakravarthy, Z. Pan, Y. Zhu, K. Tordjman, J.G. Schneider, T. Coleman, J. Turk, and C.F. Semenkovich "New" hepatic fat activates PPARalpha to maintain glucose, lipid, and cholesterol homeostasis Cell Metab. 1 2005 309 322 (Pubitemid 43977168)
-
(2005)
Cell Metabolism
, vol.1
, Issue.5
, pp. 309-322
-
-
Chakravarthy, M.V.1
Pan, Z.2
Zhu, Y.3
Tordjman, K.4
Schneider, J.G.5
Coleman, T.6
Turk, J.7
Semenkovich, C.F.8
-
35
-
-
3843061127
-
Central role for liver X receptor in insulin-mediated activation of SREBP-1c transcription and stimulation of fatty acid synthesis in liver
-
DOI 10.1073/pnas.0404297101
-
G. Chen, G. Liang, J. Ou, J.L. Goldstein, and M.S. Brown Central role for liver X receptor in insulin-mediated activation of Srebp-1c transcription and stimulation of fatty acid synthesis in liver Proc. Natl. Acad. Sci. U.S.A. 101 2004 11245 11250 (Pubitemid 39038332)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.31
, pp. 11245-11250
-
-
Chen, G.1
Liang, G.2
Ou, J.3
Goldstein, J.L.4
Brown, M.S.5
-
36
-
-
33845587711
-
Enzymatic reduction of oxysterols impairs LXR signaling in cultured cells and the livers of mice
-
DOI 10.1016/j.cmet.2006.11.012, PII S1550413106003950
-
W. Chen, G. Chen, D.L. Head, D.J. Mangelsdorf, and D.W. Russell Enzymatic reduction of oxysterols impairs LXR signaling in cultured cells and the livers of mice Cell Metab. 5 2007 73 79 (Pubitemid 44933109)
-
(2007)
Cell Metabolism
, vol.5
, Issue.1
, pp. 73-79
-
-
Chen, W.1
Chen, G.2
Head, D.L.3
Mangelsdorf, D.J.4
Russell, D.W.5
-
37
-
-
44349117420
-
AGPAT6 is a novel microsomal glycerol-3-phosphate acyltransferase
-
Y.Q. Chen, M.S. Kuo, S. Li, H.H. Bui, D.A. Peake, P.E. Sanders, S.J. Thibodeaux, S. Chu, Y.W. Qian, Y. Zhao, D.S. Bredt, D.E. Moller, R.J. Konrad, A.P. Beigneux, S.G. Young, and G. Cao AGPAT6 is a novel microsomal glycerol-3-phosphate acyltransferase J. Biol. Chem. 283 2008 10048 10057
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 10048-10057
-
-
Chen, Y.Q.1
Kuo, M.S.2
Li, S.3
Bui, H.H.4
Peake, D.A.5
Sanders, P.E.6
Thibodeaux, S.J.7
Chu, S.8
Qian, Y.W.9
Zhao, Y.10
Bredt, D.S.11
Moller, D.E.12
Konrad, R.J.13
Beigneux, A.P.14
Young, S.G.15
Cao, G.16
-
38
-
-
0035834868
-
Regulation of cholesterol 7α-hydroxylase gene (CYP7A1) transcription by the liver orphan receptor (LXRα)
-
DOI 10.1016/S0378-1119(00)00518-7, PII S0378111900005187
-
J.Y. Chiang, R. Kimmel, and D. Stroup Regulation of cholesterol 7alpha-hydroxylase gene (CYP7A1) transcription by the liver orphan receptor (LXRalpha) Gene 262 2001 257 265 (Pubitemid 32155357)
-
(2001)
Gene
, vol.262
, Issue.1-2
, pp. 257-265
-
-
Chiang, J.Y.L.1
Kimmel, R.2
Stroup, D.3
-
39
-
-
0037637624
-
Fatty acid synthesis is essential in embryonic development: Fatty acid synthase null mutants and most of the heterozygotes die in utero
-
DOI 10.1073/pnas.0931394100
-
S.S. Chirala, H. Chang, M. Matzuk, L. Abu-Elheiga, J. Mao, K. Mahon, M. Finegold, and S.J. Wakil Fatty acid synthesis is essential in embryonic development: fatty acid synthase null mutants and most of the heterozygotes die in utero Proc. Natl. Acad. Sci. U.S.A. 100 2003 6358 6363 (Pubitemid 36666586)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.11
, pp. 6358-6363
-
-
Chirala, S.S.1
Chang, H.2
Matzuk, M.3
Abu-Elheiga, L.4
Mao, J.5
Mahon, K.6
Finegold, M.7
Wakil, S.J.8
-
40
-
-
0035853039
-
Human fatty acid synthase: Role of interdomain in the formation of catalytically active synthase dimer
-
DOI 10.1073/pnas.051635998
-
S.S. Chirala, A. Jayakumar, Z.W. Gu, and S.J. Wakil Human fatty acid synthase: role of interdomain in the formation of catalytically active synthase dimer Proc. Natl. Acad. Sci. U.S.A. 98 2001 3104 3108 (Pubitemid 32220806)
-
(2001)
Proceedings of the National Academy of Sciences of the United States of America
, vol.98
, Issue.6
, pp. 3104-3108
-
-
Chirala, S.S.1
Jayakumar, A.2
Gu, Z.-W.3
Wakil, S.J.4
-
41
-
-
12344283741
-
Structure and function of animal fatty acid synthase
-
DOI 10.1007/s11745-004-1329-9
-
S.S. Chirala, and S.J. Wakil Structure and function of animal fatty acid synthase Lipids 39 2004 1045 1053 (Pubitemid 40129046)
-
(2004)
Lipids
, vol.39
, Issue.11
, pp. 1045-1053
-
-
Chirala, S.S.1
Wakil, S.J.2
-
42
-
-
33748655454
-
Stearoyl-coenzyme A desaturase 1 deficiency protects against hypertriglyceridemia and increases plasma high-density lipoprotein cholesterol induced by liver X receptor activation
-
DOI 10.1128/MCB.00077-06
-
K. Chu, M. Miyazaki, W.C. Man, and J.M. Ntambi Stearoyl-coenzyme A desaturase 1 deficiency protects against hypertriglyceridemia and increases plasma high-density lipoprotein cholesterol induced by liver X receptor activation Mol. Cell. Biol. 26 2006 6786 6798 (Pubitemid 44387629)
-
(2006)
Molecular and Cellular Biology
, vol.26
, Issue.18
, pp. 6786-6798
-
-
Chu, K.1
Miyazaki, M.2
Man, W.C.3
Ntambi, J.M.4
-
43
-
-
79952140449
-
Quantification of PtdInsP(3) molecular species in cells and tissues by mass spectrometry
-
J. Clark, K.E. Anderson, V. Juvin, T.S. Smith, F. Karpe, M.J. Wakelam, L.R. Stephens, and P.T. Hawkins Quantification of PtdInsP(3) molecular species in cells and tissues by mass spectrometry Nat. Methods 8 2011 267 272
-
(2011)
Nat. Methods
, vol.8
, pp. 267-272
-
-
Clark, J.1
Anderson, K.E.2
Juvin, V.3
Smith, T.S.4
Karpe, F.5
Wakelam, M.J.6
Stephens, L.R.7
Hawkins, P.T.8
-
44
-
-
0037067570
-
Role for stearoyl-CoA desaturase-1 in leptin-mediated weight loss
-
DOI 10.1126/science.1071527
-
P. Cohen, M. Miyazaki, N.D. Socci, A. Hagge-Greenberg, W. Liedtke, A.A. Soukas, R. Sharma, L.C. Hudgins, J.M. Ntambi, and J.M. Friedman Role for stearoyl-CoA desaturase-1 in leptin-mediated weight loss Science 297 2002 240 243 (Pubitemid 34761283)
-
(2002)
Science
, vol.297
, Issue.5579
, pp. 240-243
-
-
Cohen, P.1
Miyazaki, M.2
Socci, N.D.3
Hagge-Greenberg, A.4
Liedtke, W.5
Soukas, A.A.6
Sharma, R.7
Hudgins, L.C.8
Ntambi, J.M.9
Friedman, J.M.10
-
45
-
-
0345171460
-
Enzymes of triacylglycerol synthesis and their regulation
-
DOI 10.1016/S0163-7827(03)00051-1
-
R.A. Coleman, and D.P. Lee Enzymes of triacylglycerol synthesis and their regulation Prog. Lipid Res. 43 2004 134 176 (Pubitemid 37492937)
-
(2004)
Progress in Lipid Research
, vol.43
, Issue.2
, pp. 134-176
-
-
Coleman, R.A.1
Lee, D.P.2
-
46
-
-
0037046543
-
Identification of a nonsteroidal liver X receptor agonist through parallel array synthesis of tertiary amines
-
DOI 10.1021/jm0255116
-
J.L. Collins, A.M. Fivush, M.A. Watson, C.M. Galardi, M.C. Lewis, L.B. Moore, D.J. Parks, J.G. Wilson, T.K. Tippin, J.G. Binz, K.D. Plunket, D.G. Morgan, E.J. Beaudet, K.D. Whitney, S.A. Kliewer, and T.M. Willson Identification of a nonsteroidal liver X receptor agonist through parallel array synthesis of tertiary amines J. Med. Chem. 45 2002 1963 1966 (Pubitemid 34477709)
-
(2002)
Journal of Medicinal Chemistry
, vol.45
, Issue.10
, pp. 1963-1966
-
-
Collins, J.L.1
Fivush, A.M.2
Watson, M.A.3
Galardi, C.M.4
Lewis, M.C.5
Moore, L.B.6
Parks, D.J.7
Wilson, J.G.8
Tippin, T.K.9
Binz, J.G.10
Plunket, K.D.11
Morgan, D.G.12
Beaudet, E.J.13
Whitney, K.D.14
Kliewer, S.A.15
Willson, T.M.16
-
47
-
-
58749091644
-
Molecular mechanisms of hepatic steatosis and insulin resistance in the AGPAT2-deficient mouse model of congenital generalized lipodystrophy
-
V.A. Cortes, D.E. Curtis, S. Sukumaran, X. Shao, V. Parameswara, S. Rashid, A.R. Smith, J. Ren, V. Esser, R.E. Hammer, A.K. Agarwal, J.D. Horton, and A. Garg Molecular mechanisms of hepatic steatosis and insulin resistance in the AGPAT2-deficient mouse model of congenital generalized lipodystrophy Cell Metab. 9 2009 165 176
-
(2009)
Cell Metab.
, vol.9
, pp. 165-176
-
-
Cortes, V.A.1
Curtis, D.E.2
Sukumaran, S.3
Shao, X.4
Parameswara, V.5
Rashid, S.6
Smith, A.R.7
Ren, J.8
Esser, V.9
Hammer, R.E.10
Agarwal, A.K.11
Horton, J.D.12
Garg, A.13
-
48
-
-
0034623288
-
Sterol-dependent transactivation of the ABC1 promoter by the liver X receptor/retinoid X receptor
-
P. Costet, Y. Luo, N. Wang, and A.R. Tall Sterol-dependent transactivation of the ABC1 promoter by the liver X receptor/retinoid X receptor J. Biol. Chem. 275 2000 28240 28245
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 28240-28245
-
-
Costet, P.1
Luo, Y.2
Wang, N.3
Tall, A.R.4
-
49
-
-
79551545978
-
Liver X receptor (LXR) mediates negative regulation of mouse and human Th17 differentiation
-
G. Cui, X. Qin, L. Wu, Y. Zhang, X. Sheng, Q. Yu, H. Sheng, B. Xi, J.Z. Zhang, and Y.Q. Zang Liver X receptor (LXR) mediates negative regulation of mouse and human Th17 differentiation J. Clin. Invest. 121 2011 658 670
-
(2011)
J. Clin. Invest.
, vol.121
, pp. 658-670
-
-
Cui, G.1
Qin, X.2
Wu, L.3
Zhang, Y.4
Sheng, X.5
Yu, Q.6
Sheng, H.7
Xi, B.8
Zhang, J.Z.9
Zang, Y.Q.10
-
50
-
-
33745824191
-
Liver X receptors regulate adrenal cholesterol balance
-
DOI 10.1172/JCI28400
-
C.L. Cummins, D.H. Volle, Y. Zhang, J.G. McDonald, B. Sion, A.M. Lefrancois-Martinez, F. Caira, G. Veyssiere, D.J. Mangelsdorf, and J.M. Lobaccaro Liver X receptors regulate adrenal cholesterol balance J. Clin. Invest. 116 2006 1902 1912 (Pubitemid 44033314)
-
(2006)
Journal of Clinical Investigation
, vol.116
, Issue.7
, pp. 1902-1912
-
-
Cummins, C.L.1
Volle, D.H.2
Zhang, Y.3
McDonald, J.G.4
Sion, B.5
Lefrancois-Martinez, A.-M.6
Caira, F.7
Veyssiere, G.8
Mangelsdorf, D.J.9
Lobaccaro, J.-M.A.10
-
51
-
-
0035852770
-
Expression of sterol regulatory element-binding protein 1c (SREBP-1c) mRNA in rat hepatoma cells requires endogenous LXR ligands
-
DOI 10.1073/pnas.98.4.1477
-
R.A. DeBose-Boyd, J. Ou, J.L. Goldstein, and M.S. Brown Expression of sterol regulatory element-binding protein 1c (SREBP-1c) mRNA in rat hepatoma cells requires endogenous LXR ligands Proc. Natl. Acad. Sci. U.S.A. 98 2001 1477 1482 (Pubitemid 32165524)
-
(2001)
Proceedings of the National Academy of Sciences of the United States of America
, vol.98
, Issue.4
, pp. 1477-1482
-
-
DeBose-Boyd, R.A.1
Ou, J.2
Goldstein, J.L.3
Brown, M.S.4
-
52
-
-
40549125618
-
ChREBP, but not LXRs, is required for the induction of glucose-regulated genes in mouse liver
-
DOI 10.1172/JCI34314
-
P.D. Denechaud, P. Bossard, J.M. Lobaccaro, L. Millatt, B. Staels, J. Girard, and C. Postic ChREBP, but not LXRs, is required for the induction of glucose-regulated genes in mouse liver J. Clin. Invest. 118 2008 956 964 (Pubitemid 351364603)
-
(2008)
Journal of Clinical Investigation
, vol.118
, Issue.3
, pp. 956-964
-
-
Denechaud, P.-D.1
Bossard, P.2
Lobaccaro, J.-M.A.3
Millatt, L.4
Staels, B.5
Girard, J.6
Postic, C.7
-
53
-
-
43649094366
-
Carbohydrate responsive element binding protein and lipid homeostasis
-
DOI 10.1097/MOL.0b013e3282ffafaa, PII 0004143320080600000014
-
P.D. Denechaud, J. Girard, and C. Postic Carbohydrate responsive element binding protein and lipid homeostasis Curr. Opin. Lipidol. 19 2008 301 306 (Pubitemid 351681558)
-
(2008)
Current Opinion in Lipidology
, vol.19
, Issue.3
, pp. 301-306
-
-
Denechaud, P.-D.1
Girard, J.2
Postic, C.3
-
54
-
-
26444434340
-
Polyunsaturated fatty acids suppress glycolytic and lipogenic genes through the inhibition of ChREBP nuclear protein translocation
-
DOI 10.1172/JCI25256
-
R. Dentin, F. Benhamed, J.P. Pegorier, F. Foufelle, B. Viollet, S. Vaulont, J. Girard, and C. Postic Polyunsaturated fatty acids suppress glycolytic and lipogenic genes through the inhibition of ChREBP nuclear protein translocation J. Clin. Invest. 115 2005 2843 2854 (Pubitemid 41434411)
-
(2005)
Journal of Clinical Investigation
, vol.115
, Issue.10
, pp. 2843-2854
-
-
Dentin, R.1
Benhamed, F.2
Pegorier, J.-P.3
Foufelle, F.4
Viollet, B.5
Vaulont, S.6
Girard, J.7
Postic, C.8
-
55
-
-
2342652187
-
Stearoyl-CoA desaturase 1 deficiency increases fatty acid oxidation by activating AMP-activated protein kinase in liver
-
DOI 10.1073/pnas.0401627101
-
P. Dobrzyn, A. Dobrzyn, M. Miyazaki, P. Cohen, E. Asilmaz, D.G. Hardie, J.M. Friedman, and J.M. Ntambi Stearoyl-CoA desaturase 1 deficiency increases fatty acid oxidation by activating AMP-activated protein kinase in liver Proc. Natl. Acad. Sci. U.S.A. 101 2004 6409 6414 (Pubitemid 38585987)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.17
, pp. 6409-6414
-
-
Dobrzyn, P.1
Dobrzyn, A.2
Miyazaki, M.3
Cohen, P.4
Asilmaz, E.5
Hardie, D.G.6
Friedman, J.M.7
Ntambi, J.M.8
-
56
-
-
0027968653
-
Effects of a 2,3-oxidosqualene-lanosterol cyclase inhibitor 2,3:22,23-dioxidosqualene and 24,25-epoxycholesterol on the regulation of cholesterol biosynthesis in human hepatoma cell line HepG2
-
D. Dollis, and F. Schuber Effects of a 2,3-oxidosqualene-lanosterol cyclase inhibitor 2,3:22,23-dioxidosqualene and 24,25-epoxycholesterol on the regulation of cholesterol biosynthesis in human hepatoma cell line HepG2 Biochem. Pharmacol. 48 1994 49 57
-
(1994)
Biochem. Pharmacol.
, vol.48
, pp. 49-57
-
-
Dollis, D.1
Schuber, F.2
-
57
-
-
18244382304
-
Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease
-
DOI 10.1172/JCI200523621
-
K.L. Donnelly, C.I. Smith, S.J. Schwarzenberg, J. Jessurun, M.D. Boldt, and E.J. Parks Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease J. Clin. Invest. 115 2005 1343 1351 (Pubitemid 40629054)
-
(2005)
Journal of Clinical Investigation
, vol.115
, Issue.5
, pp. 1343-1351
-
-
Donnelly, K.L.1
Smith, C.I.2
Schwarzenberg, S.J.3
Jessurun, J.4
Boldt, M.D.5
Parks, E.J.6
-
58
-
-
0030789284
-
Human lysophosphatidic acid acyltransferase: cDNA cloning, expression, and localization to chromosome 9q34.3
-
DOI 10.1074/jbc.272.32.20299
-
C. Eberhardt, P.W. Gray, and L.W. Tjoelker Human lysophosphatidic acid acyltransferase. cDNA cloning, expression, and localization to chromosome 9q34.3 J. Biol. Chem. 272 1997 20299 20305 (Pubitemid 27340144)
-
(1997)
Journal of Biological Chemistry
, vol.272
, Issue.32
, pp. 20299-20305
-
-
Eberhardt, C.1
Gray, P.W.2
Tjoelker, L.W.3
-
59
-
-
79958272287
-
Liver X receptors, lipids and their reproductive secrets in the male
-
F.Z. El-Hajjaji, A. Oumeddour, A. Pommier, A. Ouvrier, E. Viennois, J. Dufour, F. Caira, J.R. Drevet, S. Baron, F. Saez, and J.M.A. Lobaccaro Liver X receptors, lipids and their reproductive secrets in the male BBA-Mol. Basis Dis. 1812 2011 974 981
-
(2011)
BBA-Mol. Basis Dis.
, vol.1812
, pp. 974-981
-
-
El-Hajjaji, F.Z.1
Oumeddour, A.2
Pommier, A.3
Ouvrier, A.4
Viennois, E.5
Dufour, J.6
Caira, F.7
Drevet, J.R.8
Baron, S.9
Saez, F.10
Lobaccaro, J.M.A.11
-
60
-
-
35548996710
-
DisSIRTing on LXR and cholesterol metabolism
-
DOI 10.1016/j.cmet.2007.10.003, PII S1550413107002963
-
J.N. Feige, and J. Auwerx DisSIRTing on LXR and cholesterol metabolism Cell Metab. 6 2007 343 345 (Pubitemid 350012003)
-
(2007)
Cell Metabolism
, vol.6
, Issue.5
, pp. 343-345
-
-
Feige, J.N.1
Auwerx, J.2
-
61
-
-
77957302090
-
Hepatic steatosis: A role for de novo lipogenesis and the transcription factor SREBP-1c
-
P. Ferre, and F. Foufelle Hepatic steatosis: a role for de novo lipogenesis and the transcription factor SREBP-1c Diabetes Obes. Metab. 12 Suppl. 2 2010 83 92
-
(2010)
Diabetes Obes. Metab.
, vol.12
, Issue.SUPPL. 2
, pp. 83-92
-
-
Ferre, P.1
Foufelle, F.2
-
62
-
-
0035914330
-
27-hydroxycholesterol is an endogenous ligand for liver X receptor in cholesterol-loaded cells
-
X. Fu, J.G. Menke, Y. Chen, G. Zhou, K.L. MacNaul, S.D. Wright, C.P. Sparrow, and E.G. Lund 27-hydroxycholesterol is an endogenous ligand for liver X receptor in cholesterol-loaded cells J. Biol. Chem. 276 2001 38378 38387
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 38378-38387
-
-
Fu, X.1
Menke, J.G.2
Chen, Y.3
Zhou, G.4
MacNaul, K.L.5
Wright, S.D.6
Sparrow, C.P.7
Lund, E.G.8
-
63
-
-
0032771711
-
Rat sn-glycerol-3-phosphate acyltransferase: Molecular cloning and characterization of the cDNA and expressed protein
-
DOI 10.1016/S1388-1981(99)00103-1, PII S1388198199001031
-
B. Ganesh Bhat, P. Wang, J.H. Kim, T.M. Black, T.M. Lewin, F.T. Fiedorek Jr., and R.A. Coleman Rat sn-glycerol-3-phosphate acyltransferase: molecular cloning and characterization of the cDNA and expressed protein Biochim. Biophys. Acta 1439 1999 415 423 (Pubitemid 29371807)
-
(1999)
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids
, vol.1439
, Issue.3
, pp. 415-423
-
-
Ganesh Bhat, B.1
Wang, P.2
Kim, J.-H.3
Black, T.M.4
Lewin, T.M.5
Fiedorek Jr., F.T.6
Coleman, R.A.7
-
64
-
-
53149118574
-
Sterol regulators of cholesterol homeostasis and beyond: The oxysterol hypothesis revisited and revised
-
S. Gill, R. Chow, and A.J. Brown Sterol regulators of cholesterol homeostasis and beyond: the oxysterol hypothesis revisited and revised Prog. Lipid Res. 47 2008 391 404
-
(2008)
Prog. Lipid Res.
, vol.47
, pp. 391-404
-
-
Gill, S.1
Chow, R.2
Brown, A.J.3
-
65
-
-
79952174597
-
Cholesterol-dependent degradation of squalene monooxygenase, a control point in cholesterol synthesis beyond HMG-CoA reductase
-
S. Gill, J. Stevenson, I. Kristiana, and A.J. Brown Cholesterol-dependent degradation of squalene monooxygenase, a control point in cholesterol synthesis beyond HMG-CoA reductase Cell Metab. 13 2011 260 273
-
(2011)
Cell Metab.
, vol.13
, pp. 260-273
-
-
Gill, S.1
Stevenson, J.2
Kristiana, I.3
Brown, A.J.4
-
66
-
-
66849089864
-
Thematic review series: Glycerolipids. Mammalian glycerol-3-phosphate acyltransferases: New genes for an old activity
-
R.E. Gimeno, and J. Cao Thematic review series: glycerolipids. Mammalian glycerol-3-phosphate acyltransferases: new genes for an old activity J. Lipid Res. 49 2008 2079 2088
-
(2008)
J. Lipid Res.
, vol.49
, pp. 2079-2088
-
-
Gimeno, R.E.1
Cao, J.2
-
67
-
-
0034650893
-
The coregulator exchange in transcriptional functions of nuclear receptors
-
C.K. Glass, and M.G. Rosenfeld The coregulator exchange in transcriptional functions of nuclear receptors Genes Dev. 14 2000 121 141 (Pubitemid 30070977)
-
(2000)
Genes and Development
, vol.14
, Issue.2
, pp. 121-141
-
-
Glass, C.K.1
Rosenfeld, M.G.2
-
68
-
-
0039302500
-
A branched metabolic pathway in animal cells converts 2-monoacylglycerol into sn-1-stearoyl-2-arachidonoyl phosphatidylinositol and other phosphoglycerides
-
R.W. Gross, Elsevier St. Louis, MO
-
J.A. Glosset A branched metabolic pathway in animal cells converts 2-monoacylglycerol into sn-1-stearoyl-2-arachidonoyl phosphatidylinositol and other phosphoglycerides R.W. Gross, Advances in Lipobiology vol. 1 1996 Elsevier St. Louis, MO 61 100
-
(1996)
Advances in Lipobiology
, vol.1
, pp. 61-100
-
-
Glosset, J.A.1
-
70
-
-
0033637121
-
A regulatory cascade of the nuclear receptors FXR, SHP-1, and LRH-1 represses bile acid biosynthesis
-
B. Goodwin, S.A. Jones, R.R. Price, M.A. Watson, D.D. McKee, L.B. Moore, C. Galardi, J.G. Wilson, M.C. Lewis, M.E. Roth, P.R. Maloney, T.M. Willson, and S.A. Kliewer A regulatory cascade of the nuclear receptors FXR, SHP-1, and LRH-1 represses bile acid biosynthesis Mol. Cell 6 2000 517 526
-
(2000)
Mol. Cell
, vol.6
, pp. 517-526
-
-
Goodwin, B.1
Jones, S.A.2
Price, R.R.3
Watson, M.A.4
McKee, D.D.5
Moore, L.B.6
Galardi, C.7
Wilson, J.G.8
Lewis, M.C.9
Roth, M.E.10
Maloney, P.R.11
Willson, T.M.12
Kliewer, S.A.13
-
71
-
-
0026551309
-
Fatty acids activate a chimera of the clofibric acid-activated receptor and the glucocorticoid receptor
-
M. Gottlicher, E. Widmark, Q. Li, and J.A. Gustafsson Fatty acids activate a chimera of the clofibric acid-activated receptor and the glucocorticoid receptor Proc. Natl. Acad. Sci. U.S.A. 89 1992 4653 4657
-
(1992)
Proc. Natl. Acad. Sci. U.S.A.
, vol.89
, pp. 4653-4657
-
-
Gottlicher, M.1
Widmark, E.2
Li, Q.3
Gustafsson, J.A.4
-
72
-
-
0037072732
-
Stimulation of lipogenesis by pharmacological activation of the liver X receptor leads to production of large, triglyceride-rich very low density lipoprotein particles
-
A. Grefhorst, B.M. Elzinga, P.J. Voshol, T. Plosch, T. Kok, V.W. Bloks, F.H. van der Sluijs, L.M. Havekes, J.A. Romijn, H.J. Verkade, and F. Kuipers Stimulation of lipogenesis by pharmacological activation of the liver X receptor leads to production of large, triglyceride-rich very low density lipoprotein particles J. Biol. Chem. 277 2002 34182 34190
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 34182-34190
-
-
Grefhorst, A.1
Elzinga, B.M.2
Voshol, P.J.3
Plosch, T.4
Kok, T.5
Bloks, V.W.6
Van Der Sluijs, F.H.7
Havekes, L.M.8
Romijn, J.A.9
Verkade, H.J.10
Kuipers, F.11
-
73
-
-
76749132709
-
The key roles of elongases and desaturases in mammalian fatty acid metabolism: Insights from transgenic mice
-
H. Guillou, D. Zadravec, P.G. Martin, and A. Jacobsson The key roles of elongases and desaturases in mammalian fatty acid metabolism: insights from transgenic mice Prog. Lipid Res. 49 2010 186 199
-
(2010)
Prog. Lipid Res.
, vol.49
, pp. 186-199
-
-
Guillou, H.1
Zadravec, D.2
Martin, P.G.3
Jacobsson, A.4
-
74
-
-
0036889152
-
Mitochondrial glycerol-3-phosphate acyltransferase-deficient mice have reduced weight and liver triacylglycerol content and altered glycerolipid fatty acid composition
-
DOI 10.1128/MCB.22.23.8204-8214.2002
-
L.E. Hammond, P.A. Gallagher, S. Wang, S. Hiller, K.D. Kluckman, E.L. Posey-Marcos, N. Maeda, and R.A. Coleman Mitochondrial glycerol-3-phosphate acyltransferase-deficient mice have reduced weight and liver triacylglycerol content and altered glycerolipid fatty acid composition Mol. Cell. Biol. 22 2002 8204 8214 (Pubitemid 35304054)
-
(2002)
Molecular and Cellular Biology
, vol.22
, Issue.23
, pp. 8204-8214
-
-
Hammond, L.E.1
Gallagher, P.A.2
Wang, S.3
Hiller, S.4
Kluckman, K.D.5
Posey-Marcos, E.L.6
Maeda, N.7
Coleman, R.A.8
-
75
-
-
21844451391
-
Mitochondrial glycerol-3-phosphate acyltransferase-1 is essential in liver for the metabolism of excess acyl-CoAs
-
DOI 10.1074/jbc.M503181200
-
L.E. Hammond, S. Neschen, A.J. Romanelli, G.W. Cline, O.R. Ilkayeva, G.I. Shulman, D.M. Muoio, and R.A. Coleman Mitochondrial glycerol-3-phosphate acyltransferase-1 is essential in liver for the metabolism of excess acyl-CoAs J. Biol. Chem. 280 2005 25629 25636 (Pubitemid 40962271)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.27
, pp. 25629-25636
-
-
Hammond, L.E.1
Neschen, S.2
Romanelli, A.J.3
Cline, G.W.4
Ilkayeva, O.R.5
Shulman, G.I.6
Muoio, D.M.7
Coleman, R.A.8
-
76
-
-
0034126633
-
Oxysterols induce differentiation in human keratinocytes and increase AP-1-dependent involucrin transcription
-
DOI 10.1046/j.1523-1747.2000.00895.x
-
K. Hanley, D.C. Ng, S.S. He, P. Lau, K. Min, P.M. Elias, D.D. Bikle, D.J. Mangelsdorf, M.L. Williams, and K.R. Feingold Oxysterols induce differentiation in human keratinocytes and increase Ap-1-dependent involucrin transcription J. Invest. Dermatol. 114 2000 545 553 (Pubitemid 30415343)
-
(2000)
Journal of Investigative Dermatology
, vol.114
, Issue.3
, pp. 545-553
-
-
Hanley, K.1
Ng, D.C.2
He, S.S.3
Lau, P.4
Min, K.5
Elias, P.M.6
Bikle, D.D.7
Mangelsdorf, D.J.8
Williams, M.L.9
Feingold, K.R.10
-
77
-
-
0035830840
-
Unsaturated fatty acids down-regulate srebp isoforms 1a and 1c by two mechanisms in HEK-293 cells
-
V.C. Hannah, J. Ou, A. Luong, J.L. Goldstein, and M.S. Brown Unsaturated fatty acids down-regulate srebp isoforms 1a and 1c by two mechanisms in HEK-293 cells J. Biol. Chem. 276 2001 4365 4372
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 4365-4372
-
-
Hannah, V.C.1
Ou, J.2
Luong, A.3
Goldstein, J.L.4
Brown, M.S.5
-
78
-
-
33947410264
-
Molecular cloning of a murine glycerol-3-phosphate acyltransferase-like protein 1 (xGPAT1)
-
DOI 10.1007/s11010-006-9321-5
-
N. Harada, S. Hara, M. Yoshida, T. Zenitani, K. Mawatari, M. Nakano, A. Takahashi, T. Hosaka, K. Yoshimoto, and Y. Nakaya Molecular cloning of a murine glycerol-3-phosphate acyltransferase-like protein 1 (xGPAT1) Mol. Cell. Biochem. 297 2007 41 51 (Pubitemid 46443528)
-
(2007)
Molecular and Cellular Biochemistry
, vol.297
, Issue.1-2
, pp. 41-51
-
-
Harada, N.1
Hara, S.2
Yoshida, M.3
Zenitani, T.4
Mawatari, K.5
Nakano, M.6
Takahashi, A.7
Hosaka, T.8
Yoshimoto, K.9
Nakaya, Y.10
-
79
-
-
14144251157
-
Distinct roles of insulin and liver X receptor in the induction and cleavage of sterol regulatory element-binding protein-1c
-
DOI 10.1073/pnas.0405067102
-
B.D. Hegarty, A. Bobard, I. Hainault, P. Ferre, P. Bossard, and F. Foufelle Distinct roles of insulin and liver X receptor in the induction and cleavage of sterol regulatory element-binding protein-1c Proc. Natl. Acad. Sci. U.S.A. 102 2005 791 796 (Pubitemid 40282744)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.3
, pp. 791-796
-
-
Hegarty, B.D.1
Bobard, A.2
Hainault, I.3
Ferre, P.4
Bossard, P.5
Foufelle, F.6
-
80
-
-
35649023189
-
The nuclear receptor cofactor, receptor-interacting protein 140, is required for the regulation of hepatic lipid and glucose metabolism by liver X receptor
-
DOI 10.1210/me.2007-0213
-
B. Herzog, M. Hallberg, A. Seth, A. Woods, R. White, and M.G. Parker The nuclear receptor cofactor, receptor-interacting protein 140, is required for the regulation of hepatic lipid and glucose metabolism by liver X receptor Mol. Endocrinol. 21 2007 2687 2697 (Pubitemid 350035151)
-
(2007)
Molecular Endocrinology
, vol.21
, Issue.11
, pp. 2687-2697
-
-
Herzog, B.1
Hallberg, M.2
Seth, A.3
Woods, A.4
White, R.5
Parker, M.G.6
-
81
-
-
33644752724
-
Substrate specificity of lysophosphatidic acid acyltransferase β - Evidence from membrane and whole cell assays
-
DOI 10.1194/jlr.M500435-JLR200
-
D. Hollenback, L. Bonham, L. Law, E. Rossnagle, L. Romero, H. Carew, C.K. Tompkins, D.W. Leung, J.W. Singer, and T. White Substrate specificity of lysophosphatidic acid acyltransferase beta - evidence from membrane and whole cell assays J. Lipid Res. 47 2006 593 604 (Pubitemid 43345600)
-
(2006)
Journal of Lipid Research
, vol.47
, Issue.3
, pp. 593-604
-
-
Hollenback, D.1
Bonham, L.2
Law, L.3
Rossnagle, E.4
Romero, L.5
Carew, H.6
Tompkins, C.K.7
Leung, D.W.8
Singer, J.W.9
White, T.10
-
82
-
-
79960671360
-
Cholesterol 25-hydroxylation activity of CYP3A
-
in press
-
A. Honda, T. Miyazaki, T. Ikegami, J. Iwamoto, T. Maeda, T. Hirayama, Y. Saito, T. Teramoto, and Y. Matsuzaki Cholesterol 25-hydroxylation activity of CYP3A J. Lipid Res. 2011 in press
-
(2011)
J. Lipid Res.
-
-
Honda, A.1
Miyazaki, T.2
Ikegami, T.3
Iwamoto, J.4
Maeda, T.5
Hirayama, T.6
Saito, Y.7
Teramoto, T.8
Matsuzaki, Y.9
-
83
-
-
79953177493
-
Constitutive activation of LXR in macrophages regulates metabolic and inflammatory gene expression: Identification of ARL7 as a direct target
-
C. Hong, R. Walczak, H. Dhamko, M.N. Bradley, C. Marathe, R. Boyadjian, J.V. Salazar, and P. Tontonoz Constitutive activation of LXR in macrophages regulates metabolic and inflammatory gene expression: identification of ARL7 as a direct target J. Lipid Res. 52 2011 531 539
-
(2011)
J. Lipid Res.
, vol.52
, pp. 531-539
-
-
Hong, C.1
Walczak, R.2
Dhamko, H.3
Bradley, M.N.4
Marathe, C.5
Boyadjian, R.6
Salazar, J.V.7
Tontonoz, P.8
-
84
-
-
0032104180
-
Activation of cholesterol synthesis in preference to fatty acid synthesis in liver and adipose tissue of transgenic mice overproducing sterol regulatory element-binding protein-2
-
J.D. Horton, I. Shimomura, M.S. Brown, R.E. Hammer, J.L. Goldstein, and H. Shimano Activation of cholesterol synthesis in preference to fatty acid synthesis in liver and adipose tissue of transgenic mice overproducing sterol regulatory element-binding protein-2 J. Clin. Invest. 101 1998 2331 2339 (Pubitemid 28270427)
-
(1998)
Journal of Clinical Investigation
, vol.101
, Issue.11
, pp. 2331-2339
-
-
Norton, J.D.1
Shimomura, I.2
Brown, M.S.3
Hammer, R.E.4
Goldstein, J.L.5
Shimano, H.6
-
85
-
-
50649112638
-
SIRT1 regulates hepatocyte lipid metabolism through activating AMP-activated protein kinase
-
X. Hou, S. Xu, K.A. Maitland-Toolan, K. Sato, B. Jiang, Y. Ido, F. Lan, K. Walsh, M. Wierzbicki, T.J. Verbeuren, R.A. Cohen, and M. Zang SIRT1 regulates hepatocyte lipid metabolism through activating AMP-activated protein kinase J. Biol. Chem. 283 2008 20015 20026
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 20015-20026
-
-
Hou, X.1
Xu, S.2
Maitland-Toolan, K.A.3
Sato, K.4
Jiang, B.5
Ido, Y.6
Lan, F.7
Walsh, K.8
Wierzbicki, M.9
Verbeuren, T.J.10
Cohen, R.A.11
Zang, M.12
-
86
-
-
4744354632
-
T0901317 is a dual LXR/FXR agonist
-
DOI 10.1016/j.ymgme.2004.07.007, PII S1096719204001830, ASHG 2004 Meeting Toronto
-
K.A. Houck, K.M. Borchert, C.D. Hepler, J.S. Thomas, K.S. Bramlett, L.F. Michael, and T.P. Burris T0901317 is a dual LXR/FXR agonist Mol. Genet. Metab. 83 2004 184 187 (Pubitemid 39311292)
-
(2004)
Molecular Genetics and Metabolism
, vol.83
, Issue.1-2
, pp. 184-187
-
-
Houck, K.A.1
Borchert, K.M.2
Hepler, C.D.3
Thomas, J.S.4
Bramlett, K.S.5
Michael, L.F.6
Burris, T.P.7
-
87
-
-
73949159619
-
N-3 polyunsaturated fatty acids suppress insulin-induced SREBP-1c transcription via reduced trans-activating capacity of LXRalpha
-
G. Howell III, X. Deng, C. Yellaturu, E.A. Park, H.G. Wilcox, R. Raghow, and M.B. Elam N-3 polyunsaturated fatty acids suppress insulin-induced SREBP-1c transcription via reduced trans-activating capacity of LXRalpha Biochim. Biophys. Acta 1791 2009 1190 1196
-
(2009)
Biochim. Biophys. Acta
, vol.1791
, pp. 1190-1196
-
-
Howell Iii, G.1
Deng, X.2
Yellaturu, C.3
Park, E.A.4
Wilcox, H.G.5
Raghow, R.6
Elam, M.B.7
-
88
-
-
0038517917
-
Liver X receptors interact with corepressors to regulate gene expression
-
DOI 10.1210/me.2002-0399
-
X. Hu, S. Li, J. Wu, C. Xia, and D.S. Lala Liver X receptors interact with corepressors to regulate gene expression Mol. Endocrinol. 17 2003 1019 1026 (Pubitemid 36683710)
-
(2003)
Molecular Endocrinology
, vol.17
, Issue.6
, pp. 1019-1026
-
-
Hu, X.1
Li, S.2
Wu, J.3
Xia, C.4
Lala, D.S.5
-
89
-
-
0027139362
-
SREBP-2, a second basic-helix-loop-helix-leucine zipper protein that stimulates transcription by binding to a sterol regulatory element
-
DOI 10.1073/pnas.90.24.11603
-
X. Hua, C. Yokoyama, J. Wu, M.R. Briggs, M.S. Brown, J.L. Goldstein, and X. Wang SREBP-2, a second basic-helix-loop-helix-leucine zipper protein that stimulates transcription by binding to a sterol regulatory element Proc. Natl. Acad. Sci. U.S.A. 90 1993 11603 11607 (Pubitemid 24008687)
-
(1993)
Proceedings of the National Academy of Sciences of the United States of America
, vol.90
, Issue.24
, pp. 11603-11607
-
-
Hua, X.1
Yokoyama, C.2
Wu, J.3
Briggs, M.R.4
Brown, M.S.5
Goldstein, J.L.6
Wang, X.7
-
90
-
-
2442435802
-
Deficiency of carbohydrate response element-binding protein (ChREBP) reduces lipogenesis as well as glycolysis
-
DOI 10.1073/pnas.0401516101
-
K. Iizuka, R.K. Bruick, G. Liang, J.D. Horton, and K. Uyeda Deficiency of carbohydrate response element-binding protein (ChREBP) reduces lipogenesis as well as glycolysis Proc. Natl. Acad. Sci. U.S.A. 101 2004 7281 7286 (Pubitemid 38638024)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.19
, pp. 7281-7286
-
-
Iizuka, K.1
Bruick, R.K.2
Liang, G.3
Horton, J.D.4
Uyeda, K.5
-
91
-
-
77049107111
-
Gene-gene interaction between heme oxygenase-1 and liver X receptor-beta and Alzheimer's disease risk
-
J. Infante, E. Rodriguez-Rodriguez, I. Mateo, J. Llorca, J.L. Vazquez-Higuera, J. Berciano, and O. Combarros Gene-gene interaction between heme oxygenase-1 and liver X receptor-beta and Alzheimer's disease risk Neurobiol. Aging 31 2010 710 714
-
(2010)
Neurobiol. Aging
, vol.31
, pp. 710-714
-
-
Infante, J.1
Rodriguez-Rodriguez, E.2
Mateo, I.3
Llorca, J.4
Vazquez-Higuera, J.L.5
Berciano, J.6
Combarros, O.7
-
92
-
-
70649093097
-
Lipidomics: A mass spectrometry based systems level analysis of cellular lipids
-
P.T. Ivanova, S.B. Milne, D.S. Myers, and H.A. Brown Lipidomics: a mass spectrometry based systems level analysis of cellular lipids Curr. Opin. Chem. Biol. 13 2009 526 531
-
(2009)
Curr. Opin. Chem. Biol.
, vol.13
, pp. 526-531
-
-
Ivanova, P.T.1
Milne, S.B.2
Myers, D.S.3
Brown, H.A.4
-
93
-
-
0033524420
-
Structural requirements of ligands for the oxysterol liver X receptors LXRα and LXRβ
-
DOI 10.1073/pnas.96.1.266
-
B.A. Janowski, M.J. Grogan, S.A. Jones, G.B. Wisely, S.A. Kliewer, E.J. Corey, and D.J. Mangelsdorf Structural requirements of ligands for the oxysterol liver X receptors LXRalpha and LXRbeta Proc. Natl. Acad. Sci. U.S.A. 96 1999 266 271 (Pubitemid 29036088)
-
(1999)
Proceedings of the National Academy of Sciences of the United States of America
, vol.96
, Issue.1
, pp. 266-271
-
-
Janowski, B.A.1
Grogan, M.J.2
Jones, S.A.3
Wisely, G.B.4
Kliewer, S.A.5
Corey, E.J.6
Mangelsdorf, D.J.7
-
94
-
-
0035976936
-
The hypocholesterolemic agent LY295427 reverses suppression of sterol regulatory element-binding protein processing mediated by oxysterols
-
B.A. Janowski, B. Shan, and D.W. Russell The hypocholesterolemic agent LY295427 reverses suppression of sterol regulatory element-binding protein processing mediated by oxysterols J. Biol. Chem. 276 2001 45408 45416
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 45408-45416
-
-
Janowski, B.A.1
Shan, B.2
Russell, D.W.3
-
95
-
-
0029805887
-
An oxysterol signalling pathway mediated by the nuclear receptor LXRα
-
DOI 10.1038/383728a0
-
B.A. Janowski, P.J. Willy, T.R. Devi, J.R. Falck, and D.J. Mangelsdorf An oxysterol signalling pathway mediated by the nuclear receptor LXR alpha Nature 383 1996 728 731 (Pubitemid 26360651)
-
(1996)
Nature
, vol.383
, Issue.6602
, pp. 728-731
-
-
Janowski, B.A.1
Willy, P.J.2
Devi, T.R.3
Falck, J.R.4
Mangelsdorf, D.J.5
-
96
-
-
33845595443
-
Regulation of ABCA1 expression in human keratinocytes and murine epidermis
-
DOI 10.1194/jlr.M600163-JLR200
-
Y.J. Jiang, B. Lu, P. Kim, P.M. Elias, and K.R. Feingold Regulation of ABCA1 expression in human keratinocytes and murine epidermis J. Lipid Res. 47 2006 2248 2258 (Pubitemid 44936135)
-
(2006)
Journal of Lipid Research
, vol.47
, Issue.10
, pp. 2248-2258
-
-
Jiang, Y.J.1
Lu, B.2
Kim, P.3
Elias, P.M.4
Feingold, K.R.5
-
97
-
-
0035937783
-
Multiple N-CoR complexes contain distinct histone deacetylases
-
P.L. Jones, L.M. Sachs, N. Rouse, P.A. Wade, and Y.B. Shi Multiple N-CoR complexes contain distinct histone deacetylases J. Biol. Chem. 276 2001 8807 8811
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 8807-8811
-
-
Jones, P.L.1
Sachs, L.M.2
Rouse, N.3
Wade, P.A.4
Shi, Y.B.5
-
98
-
-
0037192797
-
Direct and indirect mechanisms for regulation of fatty acid synthase gene expression by liver X receptors
-
DOI 10.1074/jbc.M111041200
-
S.B. Joseph, B.A. Laffitte, P.H. Patel, M.A. Watson, K.E. Matsukuma, R. Walczak, J.L. Collins, T.F. Osborne, and P. Tontonoz Direct and indirect mechanisms for regulation of fatty acid synthase gene expression by liver X receptors J. Biol. Chem. 277 2002 11019 11025 (Pubitemid 34952859)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.13
, pp. 11019-11025
-
-
Joseph, S.B.1
Laffitte, B.A.2
Patel, P.H.3
Watson, M.A.4
Matsukuma, K.E.5
Walczak, R.6
Collins, J.L.7
Osborne, T.F.8
Tontonoz, P.9
-
99
-
-
0032814457
-
Regulation of gene expression by dietary fat
-
DOI 10.1146/annurev.nutr.19.1.63
-
D.B. Jump, and S.D. Clarke Regulation of gene expression by dietary fat Annu. Rev. Nutr. 19 1999 63 90 (Pubitemid 29380597)
-
(1999)
Annual Review of Nutrition
, vol.19
, pp. 63-90
-
-
Jump, D.B.1
Clarke, S.D.2
-
100
-
-
0038561165
-
Xylulose 5-phosphate mediates glucose-induced lipogenesis by xylulose 5-phosphate-activated protein phosphatase in rat liver
-
DOI 10.1073/pnas.0730817100
-
T. Kabashima, T. Kawaguchi, B.E. Wadzinski, and K. Uyeda Xylulose 5-phosphate mediates glucose-induced lipogenesis by xylulose 5-phosphate-activated protein phosphatase in rat liver Proc. Natl. Acad. Sci. U.S.A. 100 2003 5107 5112 (Pubitemid 36542666)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.9
, pp. 5107-5112
-
-
Kabashima, T.1
Kawaguchi, T.2
Wadzinski, B.E.3
Uyeda, K.4
-
101
-
-
0024427057
-
Differentiation-induced gene expression in 3T3-L1 preadipocytes. A second differentially expressed gene encoding stearoyl-CoA desaturase
-
K.H. Kaestner, J.M. Ntambi, T.J. Kelly Jr., and M.D. Lane Differentiation-induced gene expression in 3T3-L1 preadipocytes. A second differentially expressed gene encoding stearoyl-CoA desaturase J. Biol. Chem. 264 1989 14755 14761 (Pubitemid 19237293)
-
(1989)
Journal of Biological Chemistry
, vol.264
, Issue.25
, pp. 14755-14761
-
-
Kaestner, K.H.1
Ntambi, J.M.2
Kelly Jr., T.J.3
Lane, M.D.4
-
102
-
-
24144490445
-
LXRs regulate the balance between fat storage and oxidation
-
DOI 10.1016/j.cmet.2005.03.001, PII S1550413105000604
-
N.Y. Kalaany, K.C. Gauthier, A.M. Zavacki, P.P. Mammen, T. Kitazume, J.A. Peterson, J.D. Horton, D.J. Garry, A.C. Bianco, and D.J. Mangelsdorf LXRs regulate the balance between fat storage and oxidation Cell Metab. 1 2005 231 244 (Pubitemid 43960607)
-
(2005)
Cell Metabolism
, vol.1
, Issue.4
, pp. 231-244
-
-
Kalaany, N.Y.1
Gauthier, K.C.2
Zavacki, A.M.3
Mammen, P.P.A.4
Kitazume, T.5
Peterson, J.A.6
Horton, J.D.7
Garry, D.J.8
Bianco, A.C.9
Mangelsdorf, D.J.10
-
103
-
-
66449137379
-
GRP78 expression inhibits insulin and ER stress-induced SREBP-1c activation and reduces hepatic steatosis in mice
-
H.L. Kammoun, H. Chabanon, I. Hainault, S. Luquet, C. Magnan, T. Koike, P. Ferre, and F. Foufelle GRP78 expression inhibits insulin and ER stress-induced SREBP-1c activation and reduces hepatic steatosis in mice J. Clin. Invest. 119 2009 1201 1215
-
(2009)
J. Clin. Invest.
, vol.119
, pp. 1201-1215
-
-
Kammoun, H.L.1
Chabanon, H.2
Hainault, I.3
Luquet, S.4
Magnan, C.5
Koike, T.6
Ferre, P.7
Foufelle, F.8
-
104
-
-
0141481039
-
Induction of intestinal ATP-binding cassette transporters by a phytosterol-derived liver X receptor agonist
-
DOI 10.1074/jbc.M304153200
-
E. Kaneko, M. Matsuda, Y. Yamada, Y. Tachibana, I. Shimomura, and M. Makishima Induction of intestinal ATP-binding cassette transporters by a phytosterol-derived liver X receptor agonist J. Biol. Chem. 278 2003 36091 36098 (Pubitemid 37139930)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.38
, pp. 36091-36098
-
-
Kaneko, E.1
Matsuda, M.2
Yamada, Y.3
Tachibana, Y.4
Shimomura, I.5
Makishima, M.6
-
105
-
-
0347034082
-
Characterization of the human ABCG1 gene. Liver X receptor activates an internal promoter that produces a novel transcript encoding an alternative form of the protein
-
DOI 10.1074/jbc.M105863200
-
M.A. Kennedy, A. Venkateswaran, P.T. Tarr, I. Xenarios, J. Kudoh, N. Shimizu, and P.A. Edwards Characterization of the human ABCG1 gene: liver X receptor activates an internal promoter that produces a novel transcript encoding an alternative form of the protein J. Biol. Chem. 276 2001 39438 39447 (Pubitemid 37371322)
-
(2001)
Journal of Biological Chemistry
, vol.276
, Issue.42
, pp. 39438-39447
-
-
Kennedy, M.A.1
Venkateswaran, A.2
Tarr, P.T.3
Xenarios, I.4
Kudoh, J.5
Shimizu, N.6
Edwards, P.A.7
-
106
-
-
14244255485
-
The liver X receptor ligaun T0901317 decreases amyloid β production in vitro and in a mouse model of Alzheimer's disease
-
DOI 10.1074/jbc.M411420200
-
R.P. Koldamova, I.M. Lefterov, M. Staufenbiel, D. Wolfe, S. Huang, J.C. Glorioso, M. Walter, M.G. Roth, and J.S. Lazo The liver X receptor ligand T0901317 decreases amyloid beta production in vitro and in a mouse model of Alzheimer's disease J. Biol. Chem. 280 2005 4079 4088 (Pubitemid 40288571)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.6
, pp. 4079-4088
-
-
Koldamova, R.P.1
Lefterov, I.M.2
Staufenbiel, M.3
Wolfe, D.4
Huang, S.5
Glorioso, J.C.6
Walter, M.7
Roth, M.G.8
Lazo, J.S.9
-
107
-
-
0036156083
-
Oxysterol stimulation of epidermal differentiation is mediated by liver X receptor-β in murine epidermis
-
DOI 10.1046/j.0022-202x.2001.01628.x
-
L.G. Komuves, M. Schmuth, A.J. Fowler, P.M. Elias, K. Hanley, M.Q. Man, A.H. Moser, J.M. Lobaccaro, M.L. Williams, D.J. Mangelsdorf, and K.R. Feingold Oxysterol stimulation of epidermal differentiation is mediated by liver X receptor-beta in murine epidermis J. Invest. Dermatol. 118 2002 25 34 (Pubitemid 34107420)
-
(2002)
Journal of Investigative Dermatology
, vol.118
, Issue.1
, pp. 25-34
-
-
Komuves, L.G.1
Schmuth, M.2
Fowler, A.J.3
Elias, P.M.4
Hanley, K.5
Man, M.-Q.6
Moser, A.H.7
Lobaccaro, J.-M.A.8
Williams, M.L.9
Mangelsdorf, D.J.10
Feingold, K.R.11
-
108
-
-
79959578732
-
Liver-X Receptors regulate de novo lipogenesis in a tissue specific manner in C57Bl/6 female mice
-
M. Korach-Andre, A. Archer, C. Gabbi, R.P. Barros, M. Pedrelli, K.R. Steffensen, A.T. Pettersson, J. Laurencikiene, P. Parini, and J.A. Gustafsson Liver-X Receptors regulate de novo lipogenesis in a tissue specific manner in C57Bl/6 female mice Am. J. Physiol. Endocrinol. Metab. 301 2011 210 222
-
(2011)
Am. J. Physiol. Endocrinol. Metab.
, vol.301
, pp. 210-222
-
-
Korach-Andre, M.1
Archer, A.2
Gabbi, C.3
Barros, R.P.4
Pedrelli, M.5
Steffensen, K.R.6
Pettersson, A.T.7
Laurencikiene, J.8
Parini, P.9
Gustafsson, J.A.10
-
109
-
-
39549097750
-
Mouse Elovl-6 promoter is an SREBP target
-
S. Kumadaki, T. Matsuzaka, T. Kato, N. Yahagi, T. Yamamoto, S. Okada, K. Kobayashi, A. Takahashi, S. Yatoh, H. Suzuki, N. Yamada, and H. Shimano Mouse Elovl-6 promoter is an SREBP target Biochem. Biophys. Res. Commun. 368 2008 261 266
-
(2008)
Biochem. Biophys. Res. Commun.
, vol.368
, pp. 261-266
-
-
Kumadaki, S.1
Matsuzaka, T.2
Kato, T.3
Yahagi, N.4
Yamamoto, T.5
Okada, S.6
Kobayashi, K.7
Takahashi, A.8
Yatoh, S.9
Suzuki, H.10
Yamada, N.11
Shimano, H.12
-
110
-
-
0034773966
-
Autoregulation of the human liver X receptor α promoter
-
DOI 10.1128/MCB.21.22.7558-7568.2001
-
B.A. Laffitte, S.B. Joseph, R. Walczak, L. Pei, D.C. Wilpitz, J.L. Collins, and P. Tontonoz Autoregulation of the human liver X receptor alpha promoter Mol. Cell. Biol. 21 2001 7558 7568 (Pubitemid 32988767)
-
(2001)
Molecular and Cellular Biology
, vol.21
, Issue.22
, pp. 7558-7568
-
-
Laffitte, B.A.1
Joseph, S.B.2
Walczak, R.3
Pei, L.4
Wilpitz, D.C.5
Collins, J.L.6
Tontonoz, P.7
-
111
-
-
0035914412
-
DGAT2 is a new diacylglycerol acyltransferase gene family: Purification, cloning, and expression in insect cells of two polypeptides from Mortierella ramanniana with diacylglycerol acyltransferase activity
-
K.D. Lardizabal, J.T. Mai, N.W. Wagner, A. Wyrick, T. Voelker, and D.J. Hawkins DGAT2 is a new diacylglycerol acyltransferase gene family: purification, cloning, and expression in insect cells of two polypeptides from Mortierella ramanniana with diacylglycerol acyltransferase activity J. Biol. Chem. 276 2001 38862 38869
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 38862-38869
-
-
Lardizabal, K.D.1
Mai, J.T.2
Wagner, N.W.3
Wyrick, A.4
Voelker, T.5
Hawkins, D.J.6
-
112
-
-
12944259150
-
Nutritional regulation of the fatty acid synthase promoter in vivo: Sterol regulatory element binding protein functions through an upstream region containing a sterol regulatory element
-
M.J. Latasa, Y.S. Moon, K.H. Kim, and H.S. Sul Nutritional regulation of the fatty acid synthase promoter in vivo: sterol regulatory element binding protein functions through an upstream region containing a sterol regulatory element Proc. Natl. Acad. Sci. U.S.A. 97 2000 10619 10624
-
(2000)
Proc. Natl. Acad. Sci. U.S.A.
, vol.97
, pp. 10619-10624
-
-
Latasa, M.J.1
Moon, Y.S.2
Kim, K.H.3
Sul, H.S.4
-
113
-
-
44649177124
-
Activating signal cointegrator-2 is an essential adaptor to recruit histone H3 lysine 4 methyltransferases MLL3 and MLL4 to the liver X receptors
-
DOI 10.1210/me.2008-0012
-
S. Lee, J. Lee, S.K. Lee, and J.W. Lee Activating signal cointegrator-2 is an essential adaptor to recruit histone H3 lysine 4 methyltransferases MLL3 and MLL4 to the liver X receptors Mol. Endocrinol. 22 2008 1312 1319 (Pubitemid 351786992)
-
(2008)
Molecular Endocrinology
, vol.22
, Issue.6
, pp. 1312-1319
-
-
Lee, S.1
Lee, J.2
Lee, S.-K.3
Lee, J.W.4
-
114
-
-
14444285707
-
Activation of the nuclear receptor LXR by oxysterols defines a new hormone response pathway
-
DOI 10.1074/jbc.272.6.3137
-
J.M. Lehmann, S.A. Kliewer, L.B. Moore, T.A. Smith-Oliver, B.B. Oliver, J.L. Su, S.S. Sundseth, D.A. Winegar, D.E. Blanchard, T.A. Spencer, and T.M. Willson Activation of the nuclear receptor LXR by oxysterols defines a new hormone response pathway J. Biol. Chem. 272 1997 3137 3140 (Pubitemid 27066798)
-
(1997)
Journal of Biological Chemistry
, vol.272
, Issue.6
, pp. 3137-3140
-
-
Lehmann, J.M.1
Kliewer, S.A.2
Moore, L.B.3
Smith-Oliver, T.A.4
Oliver, B.B.5
Su, J.-L.6
Sundseth, S.S.7
Winegar, D.A.8
Blanchard, D.E.9
Spencer, T.A.10
Willson, T.M.11
-
115
-
-
0010044876
-
The structure and functions of human lysophosphatidic acid acyltransferases
-
D.W. Leung The structure and functions of human lysophosphatidic acid acyltransferases Front. Biosci. 6 2001 D944 953
-
(2001)
Front. Biosci.
, vol.6
, pp. 944-953
-
-
Leung, D.W.1
-
116
-
-
1842741311
-
Identification of a New Glycerol-3-phosphate Acyltransferase Isoenzyme, mtGPAT2, in Mitochondria
-
DOI 10.1074/jbc.M314032200
-
T.M. Lewin, N.M. Schwerbrock, D.P. Lee, and R.A. Coleman Identification of a new glycerol-3-phosphate acyltransferase isoenzyme, mtGPAT2, in mitochondria J. Biol. Chem. 279 2004 13488 13495 (Pubitemid 38468873)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.14
, pp. 13488-13495
-
-
Lewin, T.M.1
Schwerbrock, N.M.J.2
Lee, D.P.3
Coleman, R.A.4
-
117
-
-
0141644278
-
Cloning and identification of the human LPAAT-zeta gene, a novel member of the lysophosphatidic acid acyltransferase family
-
DOI 10.1007/s10038-003-0045-z
-
D. Li, L. Yu, H. Wu, Y. Shan, J. Guo, Y. Dang, Y. Wei, and S. Zhao Cloning and identification of the human LPAAT-zeta gene, a novel member of the lysophosphatidic acid acyltransferase family J. Hum. Genet. 48 2003 438 442 (Pubitemid 37221560)
-
(2003)
Journal of Human Genetics
, vol.48
, Issue.8
, pp. 438-442
-
-
Li, D.1
Yu, L.2
Wu, H.3
Shan, Y.4
Guo, J.5
Dang, Y.6
Wei, Y.7
Zhao, S.8
-
118
-
-
33745297834
-
Glucose-dependent transcriptional regulation by an evolutionarily conserved glucose-sensing module
-
DOI 10.2337/db05-0822
-
M.V. Li, B. Chang, M. Imamura, N. Poungvarin, and L. Chan Glucose-dependent transcriptional regulation by an evolutionarily conserved glucose-sensing module Diabetes 55 2006 1179 1189 (Pubitemid 44195353)
-
(2006)
Diabetes
, vol.55
, Issue.5
, pp. 1179-1189
-
-
Li, M.V.1
Chang, B.2
Imamura, M.3
Poungvarin, N.4
Chan, L.5
-
119
-
-
77951848682
-
Glucose-6-phosphate mediates activation of the carbohydrate responsive binding protein (ChREBP)
-
M.V. Li, W. Chen, R.N. Harmancey, A.M. Nuotio-Antar, M. Imamura, P. Saha, H. Taegtmeyer, and L. Chan Glucose-6-phosphate mediates activation of the carbohydrate responsive binding protein (ChREBP) Biochem. Biophys. Res. Commun. 395 2010 395 400
-
(2010)
Biochem. Biophys. Res. Commun.
, vol.395
, pp. 395-400
-
-
Li, M.V.1
Chen, W.2
Harmancey, R.N.3
Nuotio-Antar, A.M.4
Imamura, M.5
Saha, P.6
Taegtmeyer, H.7
Chan, L.8
-
120
-
-
37249016419
-
Biosynthesis of the regulatory oxysterol, 5-cholesten-3β,25-diol 3-sulfate, in hepatocytes
-
DOI 10.1194/jlr.M700301-JLR200
-
X. Li, W.M. Pandak, S.K. Erickson, Y. Ma, L. Yin, P. Hylemon, and S. Ren Biosynthesis of the regulatory oxysterol, 5-cholesten-3beta, 25-diol 3-sulfate, in hepatocytes J. Lipid Res. 48 2007 2587 2596 (Pubitemid 350272843)
-
(2007)
Journal of Lipid Research
, vol.48
, Issue.12
, pp. 2587-2596
-
-
Li, X.1
Pandak, W.M.2
Erickson, S.K.3
Ma, Y.4
Yin, L.5
Hylemon, P.6
Ren, S.7
-
121
-
-
34948883324
-
SIRT1 deacetylates and positively regulates the nuclear receptor LXR
-
DOI 10.1016/j.molcel.2007.07.032, PII S109727650700620X
-
X. Li, S. Zhang, G. Blander, J.G. Tse, M. Krieger, and L. Guarente SIRT1 deacetylates and positively regulates the nuclear receptor LXR Mol. Cell 28 2007 91 106 (Pubitemid 47531974)
-
(2007)
Molecular Cell
, vol.28
, Issue.1
, pp. 91-106
-
-
Li, X.1
Zhang, S.2
Blander, G.3
Tse, J.G.4
Krieger, M.5
Guarente, L.6
-
122
-
-
0037088683
-
Diminished hepatic response to fasting/refeeding and liver X receptor agonists in mice with selective deficiency of sterol regulatory element-binding protein-1c
-
DOI 10.1074/jbc.M111421200
-
G. Liang, J. Yang, J.D. Horton, R.E. Hammer, J.L. Goldstein, and M.S. Brown Diminished hepatic response to fasting/refeeding and liver X receptor agonists in mice with selective deficiency of sterol regulatory element-binding protein-1c J. Biol. Chem. 277 2002 9520 9528 (Pubitemid 34953041)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.11
, pp. 9520-9528
-
-
Liang, G.1
Yang, J.2
Horton, J.D.3
Hammer, R.E.4
Goldstein, J.L.5
Brown, M.S.6
-
124
-
-
77957769750
-
FoxO1 represses LXRalpha-mediated transcriptional activity of SREBP-1c promoter in HepG2 cells
-
X. Liu, A. Qiao, Y. Ke, X. Kong, J. Liang, R. Wang, X. Ouyang, J. Zuo, Y. Chang, and F. Fang FoxO1 represses LXRalpha-mediated transcriptional activity of SREBP-1c promoter in HepG2 cells FEBS Lett. 584 2010 4330 4334
-
(2010)
FEBS Lett.
, vol.584
, pp. 4330-4334
-
-
Liu, X.1
Qiao, A.2
Ke, Y.3
Kong, X.4
Liang, J.5
Wang, R.6
Ouyang, X.7
Zuo, J.8
Chang, Y.9
Fang, F.10
-
125
-
-
77950597894
-
Down-regulation of the LXR transcriptome provides the requisite cholesterol levels to proliferating hepatocytes
-
G. Lo Sasso, N. Celli, M. Caboni, S. Murzilli, L. Salvatore, A. Morgano, M. Vacca, T. Pagliani, P. Parini, and A. Moschetta Down-regulation of the LXR transcriptome provides the requisite cholesterol levels to proliferating hepatocytes Hepatology 51 2010 1334 1344
-
(2010)
Hepatology
, vol.51
, pp. 1334-1344
-
-
Lo Sasso, G.1
Celli, N.2
Caboni, M.3
Murzilli, S.4
Salvatore, L.5
Morgano, A.6
Vacca, M.7
Pagliani, T.8
Parini, P.9
Moschetta, A.10
-
126
-
-
78651346813
-
Intestinal specific LXR activation stimulates reverse cholesterol transport and protects from atherosclerosis
-
G. Lo Sasso, S. Murzilli, L. Salvatore, I. D'Errico, M. Petruzzelli, P. Conca, Z.Y. Jiang, L. Calabresi, P. Parini, and A. Moschetta Intestinal specific LXR activation stimulates reverse cholesterol transport and protects from atherosclerosis Cell Metab. 12 2010 187 193
-
(2010)
Cell Metab.
, vol.12
, pp. 187-193
-
-
Lo Sasso, G.1
Murzilli, S.2
Salvatore, L.3
D'Errico, I.4
Petruzzelli, M.5
Conca, P.6
Jiang, Z.Y.7
Calabresi, L.8
Parini, P.9
Moschetta, A.10
-
127
-
-
78650520909
-
Lipoexpediency: De novo lipogenesis as a metabolic signal transmitter
-
I.J. Lodhi, X. Wei, and C.F. Semenkovich Lipoexpediency: de novo lipogenesis as a metabolic signal transmitter Trends Endocrinol. Metab. 22 2011 1 8
-
(2011)
Trends Endocrinol. Metab.
, vol.22
, pp. 1-8
-
-
Lodhi, I.J.1
Wei, X.2
Semenkovich, C.F.3
-
128
-
-
0030020577
-
Sterol regulation of acetyl coenzyme A carboxylase: A mechanism for coordinate control of cellular lipid
-
DOI 10.1073/pnas.93.3.1049
-
J.M. Lopez, M.K. Bennett, H.B. Sanchez, J.M. Rosenfeld, and T.F. Osborne Sterol regulation of acetyl coenzyme A carboxylase: a mechanism for coordinate control of cellular lipid Proc. Natl. Acad. Sci. U.S.A. 93 1996 1049 1053 (Pubitemid 26054367)
-
(1996)
Proceedings of the National Academy of Sciences of the United States of America
, vol.93
, Issue.3
, pp. 1049-1053
-
-
Lopez, J.M.1
Bennett, M.K.2
Sanchez, H.B.3
Rosenfeld, J.M.4
Osborne, T.F.5
-
129
-
-
12844249385
-
Cloning and characterization of murine 1-acyl-sn-glycerol 3-phosphate acyltransferases and their regulation by PPARα in murine heart
-
DOI 10.1042/BJ20041348
-
B. Lu, Y.J. Jiang, Y. Zhou, F.Y. Xu, G.M. Hatch, and P.C. Choy Cloning and characterization of murine 1-acyl-sn-glycerol 3-phosphate acyltransferases and their regulation by PPARalpha in murine heart Biochem. J. 385 2005 469 477 (Pubitemid 40165080)
-
(2005)
Biochemical Journal
, vol.385
, Issue.2
, pp. 469-477
-
-
Lu, B.1
Jiang, Y.J.2
Zhou, Y.3
Xu, F.Y.4
Hatch, G.M.5
Choy, P.C.6
-
130
-
-
33749407193
-
ChREBP·Mlx is the principal mediator of glucose-induced gene expression in the liver
-
DOI 10.1074/jbc.M601576200
-
L. Ma, L.N. Robinson, and H.C. Towle ChREBP*Mlx is the principal mediator of glucose-induced gene expression in the liver J. Biol. Chem. 281 2006 28721 28730 (Pubitemid 44507014)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.39
, pp. 28721-28730
-
-
Ma, L.1
Robinson, L.N.2
Towle, H.C.3
-
131
-
-
0033591297
-
Identification of a nuclear receptor for bite acids
-
DOI 10.1126/science.284.5418.1362
-
M. Makishima, A.Y. Okamoto, J.J. Repa, H. Tu, R.M. Learned, A. Luk, M.V. Hull, K.D. Lustig, D.J. Mangelsdorf, and B. Shan Identification of a nuclear receptor for bile acids Science 284 1999 1362 1365 (Pubitemid 29289663)
-
(1999)
Science
, vol.284
, Issue.5418
, pp. 1362-1365
-
-
Makishima, M.1
Okamoto, A.Y.2
Repa, J.J.3
Tu, H.4
Learned, R.M.5
Luk, A.6
Hull, M.V.7
Lustig, K.D.8
Mangelsdorf, D.J.9
Shan, B.10
-
132
-
-
33744781581
-
Liver-specific deletion of acetyl-CoA carboxylase 1 reduces hepatic triglyceride accumulation without affecting glucose homeostasis
-
DOI 10.1073/pnas.0603115103
-
J. Mao, F.J. DeMayo, H. Li, L. Abu-Elheiga, Z. Gu, T.E. Shaikenov, P. Kordari, S.S. Chirala, W.C. Heird, and S.J. Wakil Liver-specific deletion of acetyl-CoA carboxylase 1 reduces hepatic triglyceride accumulation without affecting glucose homeostasis Proc. Natl. Acad. Sci. U.S.A. 103 2006 8552 8557 (Pubitemid 43838493)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.22
, pp. 8552-8557
-
-
Mao, J.1
DeMayo, F.J.2
Li, H.3
Abu-Elheiga, L.4
Gu, Z.5
Shaikenov, T.E.6
Kordari, P.7
Chirala, S.S.8
Heird, W.C.9
Wakil, S.J.10
-
133
-
-
33947371320
-
Novel aspects of PPARα-mediated regulation of lipid and xenobiotic metabolism revealed through a nutrigenomic study
-
DOI 10.1002/hep.21510
-
P.G. Martin, H. Guillou, F. Lasserre, S. Dejean, A. Lan, J.M. Pascussi,
-
(2007)
Hepatology
, vol.45
, Issue.3
, pp. 767-777
-
-
Martin, P.G.P.1
Guillou, H.2
Lasserre, F.3
Dejean, S.4
Lan, A.5
Pascussi, J.-M.6
SanCristobal, M.7
Legrand, P.8
Besse, P.9
Pineau, T.10
-
134
-
-
34948904815
-
Crucial role of a long-chain fatty acid elongase, Elovl6, in obesity-induced insulin resistance
-
DOI 10.1038/nm1662, PII NM1662
-
T. Matsuzaka, H. Shimano, N. Yahagi, T. Kato, A. Atsumi, T. Yamamoto, N. Inoue, M. Ishikawa, S. Okada, N. Ishigaki, H. Iwasaki, Y. Iwasaki, T. Karasawa, S. Kumadaki, T. Matsui, M. Sekiya, K. Ohashi, A.H. Hasty, Y. Nakagawa, A. Takahashi, H. Suzuki, S. Yatoh, H. Sone, H. Toyoshima, J. Osuga, and N. Yamada Crucial role of a long-chain fatty acid elongase, Elovl6, in obesity-induced insulin resistance Nat. Med. 13 2007 1193 1202 (Pubitemid 47530641)
-
(2007)
Nature Medicine
, vol.13
, Issue.10
, pp. 1193-1202
-
-
Matsuzaka, T.1
Shimano, H.2
Yahagi, N.3
Kato, T.4
Atsumi, A.5
Yamamoto, T.6
Inoue, N.7
Ishikawa, M.8
Okada, S.9
Ishigaki, N.10
Iwasaki, H.11
Iwasaki, Y.12
Karasawa, T.13
Kumadaki, S.14
Matsui, T.15
Sekiya, M.16
Ohashi, K.17
Hasty, A.H.18
Nakagawa, Y.19
Takahashi, A.20
Suzuki, H.21
Yatoh, S.22
Sone, H.23
Toyoshima, H.24
Osuga, J.-I.25
Yamada, N.26
more..
-
135
-
-
0035988360
-
Cloning and characterization of a mammalian fatty acyl-CoA elongase as a lipogenic enzyme regulated by SREBPs
-
T. Matsuzaka, H. Shimano, N. Yahagi, T. Yoshikawa, M. Amemiya-Kudo, A.H. Hasty, H. Okazaki, Y. Tamura, Y. Iizuka, K. Ohashi, J. Osuga, A. Takahashi, S. Yato, H. Sone, S. Ishibashi, and N. Yamada Cloning and characterization of a mammalian fatty acyl-CoA elongase as a lipogenic enzyme regulated by SREBPs J. Lipid Res. 43 2002 911 920 (Pubitemid 34602613)
-
(2002)
Journal of Lipid Research
, vol.43
, Issue.6
, pp. 911-920
-
-
Matsuzaka, T.1
Shimano, H.2
Yahagi, N.3
Yoshikawa, T.4
Amemiya-Kudo, M.5
Hasty, A.H.6
Okazaki, H.7
Tamura, Y.8
Iizuka, Y.9
Ohashi, K.10
Osuga, J.-I.11
Takahashi, A.12
Yato, S.13
Sone, H.14
Ishibashi, S.15
Yamada, N.16
-
136
-
-
0031043030
-
The mitochondrial carnitine palmitoyltransferase system. From concept to molecular analysis
-
J.D. McGarry, and N.F. Brown The mitochondrial carnitine palmitoyltransferase system. From concept to molecular analysis Eur. J. Biochem. 244 1997 1 14 (Pubitemid 27079689)
-
(1997)
European Journal of Biochemistry
, vol.244
, Issue.1
, pp. 1-14
-
-
McGarry, J.D.1
Brown, N.F.2
-
137
-
-
0031568872
-
Structure of the human gene encoding sterol regulatory element binding protein 2 (SREBF2)
-
DOI 10.1006/geno.1996.4525
-
A.R. Miserez, G. Cao, L.C. Probst, and H.H. Hobbs Structure of the human gene encoding sterol regulatory element binding protein 2 (SREBF2) Genomics 40 1997 31 40 (Pubitemid 27108244)
-
(1997)
Genomics
, vol.40
, Issue.1
, pp. 31-40
-
-
Miserez, A.R.1
Cao, G.2
Probst, L.C.3
Hobbs, H.H.4
-
138
-
-
34247093820
-
T0901317 is a potent PXR ligand: Implications for the biology ascribed to LXR
-
DOI 10.1016/j.febslet.2007.03.047, PII S0014579307003195
-
N. Mitro, L. Vargas, R. Romeo, A. Koder, and E. Saez T0901317 is a potent PXR ligand: implications for the biology ascribed to LXR FEBS Lett. 581 2007 1721 1726 (Pubitemid 46602262)
-
(2007)
FEBS Letters
, vol.581
, Issue.9
, pp. 1721-1726
-
-
Mitro, N.1
Vargas, L.2
Romeo, R.3
Koder, A.4
Saez, E.5
-
139
-
-
36448991861
-
Hepatic stearoyl-CoA desaturase-1 deficiency protects mice from carbohydrate-induced adiposity and hepatic steatosis
-
DOI 10.1016/j.cmet.2007.10.014, PII S155041310700335X
-
M. Miyazaki, M.T. Flowers, H. Sampath, K. Chu, C. Otzelberger, X. Liu, and J.M. Ntambi Hepatic stearoyl-CoA desaturase-1 deficiency protects mice from carbohydrate-induced adiposity and hepatic steatosis Cell Metab. 6 2007 484 496 (Pubitemid 350163054)
-
(2007)
Cell Metabolism
, vol.6
, Issue.6
, pp. 484-496
-
-
Miyazaki, M.1
Flowers, M.T.2
Sampath, H.3
Chu, K.4
Otzelberger, C.5
Liu, X.6
Ntambi, J.M.7
-
140
-
-
0141780830
-
Identification and Characterization of Murine SCD4, a Novel Heart-specific Stearoyl-CoA Desaturase Isoform Regulated by Leptin and Dietary Factors
-
DOI 10.1074/jbc.M304724200
-
M. Miyazaki, M.J. Jacobson, W.C. Man, P. Cohen, E. Asilmaz, J.M. Friedman, and J.M. Ntambi Identification and characterization of murine SCD4, a novel heart-specific stearoyl-CoA desaturase isoform regulated by leptin and dietary factors J. Biol. Chem. 278 2003 33904 33911 (Pubitemid 37553224)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.36
, pp. 33904-33911
-
-
Miyazaki, M.1
Jacobson, M.J.2
Man, W.C.3
Cohen, P.4
Asilmaz, E.5
Friedman, J.M.6
Ntambi, J.M.7
-
141
-
-
64149083800
-
Deletion of ELOVL5 leads to fatty liver through activation of SREBP-1c in mice
-
Y.A. Moon, R.E. Hammer, and J.D. Horton Deletion of ELOVL5 leads to fatty liver through activation of SREBP-1c in mice J. Lipid Res. 50 2009 412 423
-
(2009)
J. Lipid Res.
, vol.50
, pp. 412-423
-
-
Moon, Y.A.1
Hammer, R.E.2
Horton, J.D.3
-
142
-
-
0035977004
-
Identification of a mammalian long chain fatty acyl elongase regulated by sterol regulatory element-binding proteins
-
Y.A. Moon, N.A. Shah, S. Mohapatra, J.A. Warrington, and J.D. Horton Identification of a mammalian long chain fatty acyl elongase regulated by sterol regulatory element-binding proteins J. Biol. Chem. 276 2001 45358 45366
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 45358-45366
-
-
Moon, Y.A.1
Shah, N.A.2
Mohapatra, S.3
Warrington, J.A.4
Horton, J.D.5
-
143
-
-
0030615072
-
Ro 48-8071, a new 2,3-oxidosqualene:lanosterol cyclase inhibitor lowering plasma cholesterol in hamsters, squirrel monkeys, and minipigs: Comparison to simvastatin
-
O.H. Morand, J.D. Aebi, H. Dehmlow, Y.H. Ji, N. Gains, H. Lengsfeld, and J. Himber Ro 48-8.071, a new 2,3-oxidosqualene:lanosterol cyclase inhibitor lowering plasma cholesterol in hamsters, squirrel monkeys, and minipigs: comparison to simvastatin J. Lipid Res. 38 1997 373 390 (Pubitemid 27118049)
-
(1997)
Journal of Lipid Research
, vol.38
, Issue.2
, pp. 373-390
-
-
Morand, O.H.1
Aebi, J.D.2
Dehmlow, H.3
Ji, Y.-H.4
Gains, N.5
Lengsfeld, H.6
Himber, J.7
-
144
-
-
67649645087
-
Absence of nuclear receptors for oxysterols liver X receptor induces ovarian hyperstimulation syndrome in mice
-
K. Mouzat, F. Volat, S. Baron, G. Alves, A.J. Pommier, D.H. Volle, G. Marceau, A. DeHaze, P. Dechelotte, R. Duggavathi, F. Caira, and J.M. Lobaccaro Absence of nuclear receptors for oxysterols liver X receptor induces ovarian hyperstimulation syndrome in mice Endocrinology 150 2009 3369 3375
-
(2009)
Endocrinology
, vol.150
, pp. 3369-3375
-
-
Mouzat, K.1
Volat, F.2
Baron, S.3
Alves, G.4
Pommier, A.J.5
Volle, D.H.6
Marceau, G.7
Dehaze, A.8
Dechelotte, P.9
Duggavathi, R.10
Caira, F.11
Lobaccaro, J.M.12
-
145
-
-
44949176737
-
Identification of a novel sn-glycerol-3-phosphate acyltransferase isoform, GPAT4, as the enzyme deficient in Agpat6-/- mice
-
C.A. Nagle, L. Vergnes, H. Dejong, S. Wang, T.M. Lewin, K. Reue, and R.A. Coleman Identification of a novel sn-glycerol-3-phosphate acyltransferase isoform, GPAT4, as the enzyme deficient in Agpat6-/- mice J. Lipid Res. 49 2008 823 831
-
(2008)
J. Lipid Res.
, vol.49
, pp. 823-831
-
-
Nagle, C.A.1
Vergnes, L.2
Dejong, H.3
Wang, S.4
Lewin, T.M.5
Reue, K.6
Coleman, R.A.7
-
146
-
-
0019420840
-
Biosynthesis of 24,25-epoxycholesterol from squalene 2,3;22,23-dioxide
-
J.A. Nelson, S.R. Steckbeck, and T.A. Spencer Biosynthesis of 24,25-epoxycholesterol from squalene 2,3;22,23-dioxide J. Biol. Chem. 256 1981 1067 1068 (Pubitemid 11157204)
-
(1981)
Journal of Biological Chemistry
, vol.256
, Issue.3
, pp. 1067-1068
-
-
Nelson, J.A.1
Steckbeck, S.R.2
Spencer, T.A.3
-
147
-
-
27244440736
-
Prevention of hepatic steatosis and hepatic insulin resistance in mitochondrial acyl-CoA:glycerol-sn-3-phosphate acyltransferase 1 knockout mice
-
DOI 10.1016/j.cmet.2005.06.006, PII S1550413105001713
-
S. Neschen, K. Morino, L.E. Hammond, D. Zhang, Z.X. Liu, A.J. Romanelli, G.W. Cline, R.L. Pongratz, X.M. Zhang, C.S. Choi, R.A. Coleman, and G.I. Shulman Prevention of hepatic steatosis and hepatic insulin resistance in mitochondrial acyl-CoA:glycerol-sn-3-phosphate acyltransferase 1 knockout mice Cell Metab. 2 2005 55 65 (Pubitemid 43239825)
-
(2005)
Cell Metabolism
, vol.2
, Issue.1
, pp. 55-65
-
-
Neschen, S.1
Morino, K.2
Hammond, L.E.3
Zhang, D.4
Liu, Z.-X.5
Romanelli, A.J.6
Cline, G.W.7
Pongratz, R.L.8
Zhang, X.-M.9
Choi, C.S.10
Coleman, R.A.11
Shulman, G.I.12
-
148
-
-
0032871502
-
Regulation of stearoyl-CoA desaturase by polyunsaturated fatty acids and cholesterol
-
J.M. Ntambi Regulation of stearoyl-CoA desaturase by polyunsaturated fatty acids and cholesterol J. Lipid Res. 40 1999 1549 1558 (Pubitemid 29418696)
-
(1999)
Journal of Lipid Research
, vol.40
, Issue.9
, pp. 1549-1558
-
-
Ntambi, J.M.1
-
149
-
-
0024297268
-
Differentiation-induced gene expression in 3T3-L1 preadipocytes. Characterization of a differentially expressed gene encoding stearoyl-CoA desaturase
-
J.M. Ntambi, S.A. Buhrow, K.H. Kaestner, R.J. Christy, E. Sibley, T.J. Kelly Jr., and M.D. Lane Differentiation-induced gene expression in 3T3-L1 preadipocytes. Characterization of a differentially expressed gene encoding stearoyl-CoA desaturase J. Biol. Chem. 263 1988 17291 17300
-
(1988)
J. Biol. Chem.
, vol.263
, pp. 17291-17300
-
-
Ntambi, J.M.1
Buhrow, S.A.2
Kaestner, K.H.3
Christy, R.J.4
Sibley, E.5
Kelly, Jr.T.J.6
Lane, M.D.7
-
150
-
-
0037143752
-
Loss of stearoyl-CoA desaturase-1 function protects mice against adiposity
-
DOI 10.1073/pnas.132384699
-
J.M. Ntambi, M. Miyazaki, J.P. Stoehr, H. Lan, C.M. Kendziorski, B.S. Yandell, Y. Song, P. Cohen, J.M. Friedman, and A.D. Attie Loss of stearoyl-CoA desaturase-1 function protects mice against adiposity Proc. Natl. Acad. Sci. U.S.A. 99 2002 11482 11486 (Pubitemid 34920951)
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, Issue.17
, pp. 11482-11486
-
-
Ntambi, J.M.1
Miyazaki, M.2
Stoehr, J.P.3
Lan, H.4
Kendziorski, C.M.5
Yandell, B.S.6
Song, Y.7
Cohen, P.8
Friedman, J.M.9
Attie, A.D.10
-
151
-
-
0035844297
-
Glucose regulation of the acetyl-CoA carboxylase promoter PI in rat hepatocytes
-
B.L. O'Callaghan, S.H. Koo, Y. Wu, H.C. Freake, and H.C. Towle Glucose regulation of the acetyl-CoA carboxylase promoter PI in rat hepatocytes J. Biol. Chem. 276 2001 16033 16039
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 16033-16039
-
-
O'Callaghan, B.L.1
Koo, S.H.2
Wu, Y.3
Freake, H.C.4
Towle, H.C.5
-
152
-
-
0032500641
-
Characterization of two human genes encoding acyl coenzyme A: Cholesterol acyltransferase-related enzymes
-
DOI 10.1074/jbc.273.41.26765
-
P. Oelkers, A. Behari, D. Cromley, J.T. Billheimer, and S.L. Sturley Characterization of two human genes encoding acyl coenzyme A:cholesterol acyltransferase-related enzymes J. Biol. Chem. 273 1998 26765 26771 (Pubitemid 28471693)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.41
, pp. 26765-26771
-
-
Oelkers, P.1
Behari, A.2
Cromley, D.3
Billheimer, J.T.4
Sturleyt, S.L.5
-
153
-
-
0035932990
-
Unsaturated fatty acids inhibit transcription of the sterol regulatory element-binding protein-1c (SREBP-1c) gene by antagonizing ligand-dependent activation of the LXR
-
DOI 10.1073/pnas.111138698
-
J. Ou, H. Tu, B. Shan, A. Luk, R.A. DeBose-Boyd, Y. Bashmakov, J.L. Goldstein, and M.S. Brown Unsaturated fatty acids inhibit transcription of the sterol regulatory element-binding protein-1c (SREBP-1c) gene by antagonizing ligand-dependent activation of the LXR Proc. Natl. Acad. Sci. U.S.A. 98 2001 6027 6032 (Pubitemid 32488187)
-
(2001)
Proceedings of the National Academy of Sciences of the United States of America
, vol.98
, Issue.11
, pp. 6027-6032
-
-
Ou, J.1
Tu, H.2
Shan, B.3
Luk, A.4
DeBose-Boyd, R.A.5
Bashmakov, Y.6
Goldstein, J.L.7
Brown, M.S.8
-
154
-
-
79953737607
-
MicroRNA hsa-miR-613 targets the human LXR{alpha} gene and mediates a feedback loop of LXR{alpha} autoregulation
-
Z. Ou, T. Wada, R. Gramignoli, S. Li, S.C. Strom, M. Huang, and W. Xie MicroRNA hsa-miR-613 targets the human LXR{alpha} gene and mediates a feedback loop of LXR{alpha} autoregulation Mol. Endocrinol. 25 2011 584 596
-
(2011)
Mol. Endocrinol.
, vol.25
, pp. 584-596
-
-
Ou, Z.1
Wada, T.2
Gramignoli, R.3
Li, S.4
Strom, S.C.5
Huang, M.6
Xie, W.7
-
155
-
-
0022905095
-
Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity and cholesterol biosynthesis by oxylanosterols
-
S.R. Panini, R.C. Sexton, A.K. Gupta, E.J. Parish, S. Chitrakorn, and H. Rudney Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity and cholesterol biosynthesis by oxylanosterols J. Lipid Res. 27 1986 1190 1204 (Pubitemid 17233750)
-
(1986)
Journal of Lipid Research
, vol.27
, Issue.11
, pp. 1190-1204
-
-
Panini, S.R.1
Sexton, R.C.2
Gupta, A.K.3
-
156
-
-
0142103471
-
The role of liver X receptor-α in the fatty acid regulation of hepatic gene expression
-
DOI 10.1074/jbc.M307973200
-
A. Pawar, D. Botolin, D.J. Mangelsdorf, and D.B. Jump The role of liver X receptor-α in the fatty acid regulation of hepatic gene expression J. Biol. Chem. 278 2003 40736 40743 (Pubitemid 37280889)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.42
, pp. 40736-40743
-
-
Pawar, A.1
Botolin, D.2
Mangelsdorf, D.J.3
Jump, D.B.4
-
157
-
-
0037131234
-
Fatty acid regulation of liver X receptors (LXR) and peroxisome proliferator-activated receptor α (PPARα) in HEK293 cells
-
DOI 10.1074/jbc.M206170200
-
A. Pawar, J. Xu, E. Jerks, D.J. Mangelsdorf, and D.B. Jump Fatty acid regulation of liver X receptors (LXR) and peroxisome proliferator-activated receptor alpha (PPARalpha) in HEK293 cells J. Biol. Chem. 277 2002 39243 39250 (Pubitemid 35190894)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.42
, pp. 39243-39250
-
-
Pawar, A.1
Xu, J.2
Jerks, E.3
Mangelsdorf, D.J.4
Jump, D.B.5
-
158
-
-
0013199471
-
Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXRα
-
DOI 10.1016/S0092-8674(00)81432-4
-
D.J. Peet, S.D. Turley, W. Ma, B.A. Janowski, J.M. Lobaccaro, R.E. Hammer, and D.J. Mangelsdorf Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXR alpha Cell 93 1998 693 704 (Pubitemid 28257577)
-
(1998)
Cell
, vol.93
, Issue.5
, pp. 693-704
-
-
Peet, D.J.1
Turley, S.D.2
Ma, W.3
Janowski, B.A.4
Lobaccaro, J.-M.A.5
Hammer, R.E.6
Mangelsdorf, D.J.7
-
159
-
-
77952242043
-
Liver X Receptor activation downregulates AKT survival signaling in lipid rafts and induces apoptosis of prostate cancer cells
-
A.J. Pommier, G. Alves, E. Viennois, S. Bernard, Y. Communal, B. Sion, G. Marceau, C. Damon, K. Mouzat, F. Caira, S. Baron, and J.M. Lobaccaro Liver X Receptor activation downregulates AKT survival signaling in lipid rafts and induces apoptosis of prostate cancer cells Oncogene 29 2010 2712 2723
-
(2010)
Oncogene
, vol.29
, pp. 2712-2723
-
-
Pommier, A.J.1
Alves, G.2
Viennois, E.3
Bernard, S.4
Communal, Y.5
Sion, B.6
Marceau, G.7
Damon, C.8
Mouzat, K.9
Caira, F.10
Baron, S.11
Lobaccaro, J.M.12
-
160
-
-
77958595135
-
SIRT1 deacetylates and inhibits SREBP-1C activity in regulation of hepatic lipid metabolism
-
B. Ponugoti, D.H. Kim, Z. Xiao, Z. Smith, J. Miao, M. Zang, S.Y. Wu, C.M. Chiang, T.D. Veenstra, and J.K. Kemper SIRT1 deacetylates and inhibits SREBP-1C activity in regulation of hepatic lipid metabolism J. Biol. Chem. 285 2010 33959 33970
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 33959-33970
-
-
Ponugoti, B.1
Kim, D.H.2
Xiao, Z.3
Smith, Z.4
Miao, J.5
Zang, M.6
Wu, S.Y.7
Chiang, C.M.8
Veenstra, T.D.9
Kemper, J.K.10
-
161
-
-
40549135297
-
Contribution of de novo fatty acid synthesis to hepatic steatosis and insulin resistance: Lessons from genetically engineered mice
-
DOI 10.1172/JCI34275
-
C. Postic, and J. Girard Contribution of de novo fatty acid synthesis to hepatic steatosis and insulin resistance: lessons from genetically engineered mice J. Clin. Invest. 118 2008 829 838 (Pubitemid 351364588)
-
(2008)
Journal of Clinical Investigation
, vol.118
, Issue.3
, pp. 829-838
-
-
Postic, C.1
Girard, J.2
-
162
-
-
0034669025
-
Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRalpha and LXRbeta
-
J.J. Repa, G. Liang, J. Ou, Y. Bashmakov, J.M. Lobaccaro, I. Shimomura, B. Shan, M.S. Brown, J.L. Goldstein, and D.J. Mangelsdorf Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRalpha and LXRbeta Genes Dev. 14 2000 2819 2830
-
(2000)
Genes Dev.
, vol.14
, pp. 2819-2830
-
-
Repa, J.J.1
Liang, G.2
Ou, J.3
Bashmakov, Y.4
Lobaccaro, J.M.5
Shimomura, I.6
Shan, B.7
Brown, M.S.8
Goldstein, J.L.9
Mangelsdorf, D.J.10
-
163
-
-
0034518420
-
The role of orphan nuclear receptors in the regulation of cholesterol homeostasis
-
DOI 10.1146/annurev.cellbio.16.1.459
-
J.J. Repa, and D.J. Mangelsdorf The role of orphan nuclear receptors in the regulation of cholesterol homeostasis Annu. Rev. Cell Dev. Biol. 16 2000 459 481 (Pubitemid 32037514)
-
(2000)
Annual Review of Cell and Developmental Biology
, vol.16
, pp. 459-481
-
-
Repa, J.J.1
Mangelsdorf, D.J.2
-
164
-
-
0034284918
-
Regulation of absorption and ABC1-mediated efflux of cholesterol by RXR heterodimers
-
J.J. Repa, S.D. Turley, J.A. Lobaccaro, J. Medina, L. Li, K. Lustig, B. Shan, R.A. Heyman, J.M. Dietschy, and D.J. Mangelsdorf Regulation of absorption and ABC1-mediated efflux of cholesterol by RXR heterodimers Science 289 2000 1524 1529
-
(2000)
Science
, vol.289
, pp. 1524-1529
-
-
Repa, J.J.1
Turley, S.D.2
Lobaccaro, J.A.3
Medina, J.4
Li, L.5
Lustig, K.6
Shan, B.7
Heyman, R.A.8
Dietschy, J.M.9
Mangelsdorf, D.J.10
-
165
-
-
21044439788
-
The liver X receptor-β is essential for maintaining cholesterol homeostasis in the testis
-
DOI 10.1210/en.2004-1413
-
K.M. Robertson, G.U. Schuster, K.R. Steffensen, O. Hovatta, S. Meaney, K. Hultenby, L.C. Johansson, K. Svechnikov, O. Soder, and J.A. Gustafsson The liver X receptor-{beta} is essential for maintaining cholesterol homeostasis in the testis Endocrinology 146 2005 2519 2530 (Pubitemid 40695554)
-
(2005)
Endocrinology
, vol.146
, Issue.6
, pp. 2519-2530
-
-
Robertson, K.M.1
Schuster, G.U.2
Steffensen, K.R.3
Hovatta, O.4
Meaney, S.5
Hultenby, K.6
Johansson, L.C.7
Svechnikov, K.8
Soder, O.9
Gustafsson, J.-A.10
-
166
-
-
0035877604
-
Involvement of a unique carbohydrate-responsive factor in the glucose regulation of rat liver fatty-acid synthase gene transcription
-
C. Rufo, M. Teran-Garcia, M.T. Nakamura, S.H. Koo, H.C. Towle, and S.D. Clarke Involvement of a unique carbohydrate-responsive factor in the glucose regulation of rat liver fatty-acid synthase gene transcription J. Biol. Chem. 276 2001 21969 21975
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 21969-21975
-
-
Rufo, C.1
Teran-Garcia, M.2
Nakamura, M.T.3
Koo, S.H.4
Towle, H.C.5
Clarke, S.D.6
-
167
-
-
0034672672
-
Oxysterol biosynthetic enzymes
-
D.W. Russell Oxysterol biosynthetic enzymes Biochim. Biophys. Acta 1529 2000 126 135
-
(2000)
Biochim. Biophys. Acta
, vol.1529
, pp. 126-135
-
-
Russell, D.W.1
-
168
-
-
78649443736
-
The role of O-linked GlcNAc modification on the glucose response of ChREBP
-
H. Sakiyama, N. Fujiwara, T. Noguchi, H. Eguchi, D. Yoshihara, K. Uyeda, and K. Suzuki The role of O-linked GlcNAc modification on the glucose response of ChREBP Biochem. Biophys. Res. Commun. 402 2010 784 789
-
(2010)
Biochem. Biophys. Res. Commun.
, vol.402
, pp. 784-789
-
-
Sakiyama, H.1
Fujiwara, N.2
Noguchi, T.3
Eguchi, H.4
Yoshihara, D.5
Uyeda, K.6
Suzuki, K.7
-
169
-
-
0022341712
-
Identification of regulatory oxysterols, 24(S),25-epoxycholesterol and 25-hydroxycholesterol, in cultured fibroblasts
-
S.E. Saucier, A.A. Kandutsch, F.R. Taylor, T.A. Spencer, S. Phirwa, and A.K. Gayen Identification of regulatory oxysterols, 24(S), 25-epoxycholesterol and 25-hydroxycholesterol, in cultured fibroblasts J. Biol. Chem. 260 1985 14571 14579 (Pubitemid 16210980)
-
(1985)
Journal of Biological Chemistry
, vol.260
, Issue.27
, pp. 14571-14579
-
-
Saucier, S.E.1
Kandutsch, A.A.2
Taylor, F.R.3
-
170
-
-
0342316532
-
Oxysterols: Modulators of cholesterol metabolism and other processes
-
G.J. Schroepfer Jr. Oxysterols: modulators of cholesterol metabolism and other processes Physiol. Rev. 80 2000 361 554 (Pubitemid 30060568)
-
(2000)
Physiological Reviews
, vol.80
, Issue.1
, pp. 361-554
-
-
Schroepfer Jr., G.J.1
Wilson, W.K.2
-
171
-
-
0034669171
-
Role of LXRs in control of lipogenesis
-
J.R. Schultz, H. Tu, A. Luk, J.J. Repa, J.C. Medina, L. Li, S. Schwendner, S. Wang, M. Thoolen, D.J. Mangelsdorf, K.D. Lustig, and B. Shan Role of LXRs in control of lipogenesis Genes Dev. 14 2000 2831 2838
-
(2000)
Genes Dev.
, vol.14
, pp. 2831-2838
-
-
Schultz, J.R.1
Tu, H.2
Luk, A.3
Repa, J.J.4
Medina, J.C.5
Li, L.6
Schwendner, S.7
Wang, S.8
Thoolen, M.9
Mangelsdorf, D.J.10
Lustig, K.D.11
Shan, B.12
-
172
-
-
0345448923
-
Polyunsaturated fatty acids ameliorate hepatic steatosis in obese mice by SREBP-1 suppression
-
DOI 10.1016/j.hep.2003.09.028
-
M. Sekiya, N. Yahagi, T. Matsuzaka, Y. Najima, M. Nakakuki, R. Nagai, S. Ishibashi, J. Osuga, N. Yamada, and H. Shimano Polyunsaturated fatty acids ameliorate hepatic steatosis in obese mice by SREBP-1 suppression Hepatology 38 2003 1529 1539 (Pubitemid 37466979)
-
(2003)
Hepatology
, vol.38
, Issue.6
, pp. 1529-1539
-
-
Sekiya, M.1
Yahagi, N.2
Matsuzaka, T.3
Najima, Y.4
Nakakuki, M.5
Nagai, R.6
Ishibashi, S.7
Osuga, J.-I.8
Yamada, N.9
Shimano, H.10
-
173
-
-
1642457373
-
CYP3A induction by liver X receptor ligands in primary cultured rat and mouse hepatocytes is mediated by the pregnane X receptor
-
DOI 10.1124/dmd.32.1.66
-
S.D. Shenoy, T.A. Spencer, N.A. Mercer-Haines, M. Alipour, M.D. Gargano, M. Runge-Morris, and T.A. Kocarek CYP3A induction by liver X receptor ligands in primary cultured rat and mouse hepatocytes is mediated by the pregnane X receptor Drug Metab. Dispos. 32 2004 66 71 (Pubitemid 38112537)
-
(2004)
Drug Metabolism and Disposition
, vol.32
, Issue.1
, pp. 66-71
-
-
Shenoy, S.D.1
Spencer, T.A.2
Mercer-Haines, N.A.3
Alipour, M.4
Gargano, M.D.5
Runge-Morris, M.6
Kocarek, T.A.7
-
174
-
-
77954956306
-
Lipidomics: Coming to grips with lipid diversity
-
A. Shevchenko, and K. Simons Lipidomics: coming to grips with lipid diversity Nat. Rev. Mol. Cell Biol. 11 2010 593 598
-
(2010)
Nat. Rev. Mol. Cell Biol.
, vol.11
, pp. 593-598
-
-
Shevchenko, A.1
Simons, K.2
-
175
-
-
0030907175
-
Isoform 1c of sterol regulatory element binding protein is less active than isoform 1a in livers of transgenic mice and in cultured cells
-
H. Shimano, J.D. Horton, I. Shimomura, R.E. Hammer, M.S. Brown, and J.L. Goldstein Isoform 1c of sterol regulatory element binding protein is less active than isoform 1a in livers of transgenic mice and in cultured cells J. Clin. Invest. 99 1997 846 854 (Pubitemid 27123620)
-
(1997)
Journal of Clinical Investigation
, vol.99
, Issue.5
, pp. 846-854
-
-
Shimano, H.1
Horton, J.D.2
Shimomura, I.3
Hammer, R.E.4
Brown, M.S.5
Goldstein, J.L.6
-
176
-
-
0033544940
-
Sterol regulatory element-binding protein-1 as a key transcription factor for nutritional induction of lipogenic enzyme genes
-
H. Shimano, N. Yahagi, M. Amemiya-Kudo, A.H. Hasty, J. Osuga, Y. Tamura, F. Shionoiri, Y. Iizuka, K. Ohashi, K. Harada, T. Gotoda, S. Ishibashi, and N. Yamada Sterol regulatory element-binding protein-1 as a key transcription factor for nutritional induction of lipogenic enzyme genes J. Biol. Chem. 274 1999 35832 35839 (Pubitemid 129512888)
-
(1999)
Journal of Biological Chemistry
, vol.274
, Issue.50
, pp. 35832-35839
-
-
Shimano, H.1
Yahagi, N.2
Amemiya-Kudo, M.3
Hasty, A.H.4
Osuga, J.-I.5
Tamura, Y.6
Shionoiri, F.7
Iizuka, Y.8
Ohashi, K.9
Harada, K.10
Gotoda, T.11
Ishibashi, S.12
Yamada, N.13
-
177
-
-
0030961960
-
Differential expression of exons 1a and 1c in mRNAs for sterol regulatory element binding protein-1 in human and mouse organs and cultured cells
-
I. Shimomura, H. Shimano, J.D. Horton, J.L. Goldstein, and M.S. Brown Differential expression of exons 1a and 1c in mRNAs for sterol regulatory element binding protein-1 in human and mouse organs and cultured cells J. Clin. Invest. 99 1997 838 845 (Pubitemid 27123619)
-
(1997)
Journal of Clinical Investigation
, vol.99
, Issue.5
, pp. 838-845
-
-
Shimomura, I.1
Shimano, H.2
Horton, J.D.3
Goldstein, J.L.4
Brown, M.S.5
-
178
-
-
0023243055
-
Cholesterol autoxidation 1981-1986
-
L.L. Smith Cholesterol autoxidation 1981-1986 Chem. Phys. Lipids 44 1987 87 125 (Pubitemid 17146543)
-
(1987)
Chemistry and Physics of Lipids
, vol.44
, Issue.2-4
, pp. 87-125
-
-
Smith, L.L.1
-
179
-
-
0028557012
-
The animal fatty acid synthase: One gene, one polypeptide, seven enzymes
-
S. Smith The animal fatty acid synthase: one gene, one polypeptide, seven enzymes FASEB J. 8 1994 1248 1259
-
(1994)
FASEB J.
, vol.8
, pp. 1248-1259
-
-
Smith, S.1
-
180
-
-
0034103658
-
Obesity resistance and multiple mechanisms of triglyceride synthesis in mice lacking Dgat
-
DOI 10.1038/75651
-
S.J. Smith, S. Cases, D.R. Jensen, H.C. Chen, E. Sande, B. Tow, D.A. Sanan, J. Raber, R.H. Eckel, and R.V. Farese Jr. Obesity resistance and multiple mechanisms of triglyceride synthesis in mice lacking Dgat Nat. Genet. 25 2000 87 90 (Pubitemid 30257043)
-
(2000)
Nature Genetics
, vol.25
, Issue.1
, pp. 87-90
-
-
Smith, S.J.1
Cases, S.2
Jensen, D.R.3
Chen, H.C.4
Sande, E.5
Tow, B.6
Sanan, D.A.7
Raber, J.8
Eckel, R.H.9
Farese Jr., R.V.10
-
181
-
-
3142654791
-
Ubiquitination of 3-hydroxy-3-methylglutaryl-CoA reductase in permeabilized cells mediated by cytosolic E1 and a putative membrane-bound ubiquitin ligase
-
B.L. Song, and R.A. DeBose-Boyd Ubiquitination of 3-hydroxy-3- methylglutaryl-CoA reductase in permeabilized cells mediated by cytosolic E1 and a putative membrane-bound ubiquitin ligase J. Biol. Chem. 279 2004 28798 28806
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 28798-28806
-
-
Song, B.L.1
Debose-Boyd, R.A.2
-
182
-
-
0035372651
-
Auto-oxidized cholesterol sulfates are antagonistic ligands of liver X receptors: Implications for the development and treatment of atherosclerosis
-
DOI 10.1016/S0039-128X(00)00239-7, PII S0039128X00002397
-
C. Song, R.A. Hiipakka, and S. Liao Auto-oxidized cholesterol sulfates are antagonistic ligands of liver X receptors: implications for the development and treatment of atherosclerosis Steroids 66 2001 473 479 (Pubitemid 32140924)
-
(2001)
Steroids
, vol.66
, Issue.6
, pp. 473-479
-
-
Song, C.1
Hiipakka, R.A.2
Liao, S.3
-
183
-
-
0036135597
-
Synthesis of triacylglycerols by the acyl-coenzyme A:diacyl-glycerol acyltransferase Dga1p in lipid particles of the yeast Saccharomyces cerevisiae
-
D. Sorger, and G. Daum Synthesis of triacylglycerols by the acyl-coenzyme A:diacyl-glycerol acyltransferase Dga1p in lipid particles of the yeast Saccharomyces cerevisiae J. Bacteriol. 184 2002 519 524 (Pubitemid 34027393)
-
(2002)
Journal of Bacteriology
, vol.184
, Issue.2
, pp. 519-524
-
-
Sorger, D.1
Daum, G.2
-
184
-
-
79957620045
-
LXR as a novel antithrombotic target
-
M. Spyridon, L.A. Moraes, C.I. Jones, T. Sage, P. Sasikumar, G. Bucci, and J.M. Gibbins LXR as a novel antithrombotic target Blood 117 2011 5751 5761
-
(2011)
Blood
, vol.117
, pp. 5751-5761
-
-
Spyridon, M.1
Moraes, L.A.2
Jones, C.I.3
Sage, T.4
Sasikumar, P.5
Bucci, G.6
Gibbins, J.M.7
-
185
-
-
2442614148
-
Mlx is the functional heteromeric partner of the carbohydrate response element-binding protein in glucose regulation of lipogenic enzyme genes
-
DOI 10.1074/jbc.M311301200
-
A.K. Stoeckman, L. Ma, and H.C. Towle Mlx is the functional heteromeric partner of the carbohydrate response element-binding protein in glucose regulation of lipogenic enzyme genes J. Biol. Chem. 279 2004 15662 15669 (Pubitemid 38618968)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.15
, pp. 15662-15669
-
-
Stoeckman, A.K.1
Ma, L.2
Towle, H.C.3
-
186
-
-
64149132208
-
The endoplasmic reticulum enzyme DGAT2 is found in mitochondria- associated membranes and has a mitochondrial targeting signal that promotes its association with mitochondria
-
S.J. Stone, M.C. Levin, P. Zhou, J. Han, T.C. Walther, and R.V. Farese Jr. The endoplasmic reticulum enzyme DGAT2 is found in mitochondria-associated membranes and has a mitochondrial targeting signal that promotes its association with mitochondria J. Biol. Chem. 284 2009 5352 5361
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 5352-5361
-
-
Stone, S.J.1
Levin, M.C.2
Zhou, P.3
Han, J.4
Walther, T.C.5
Farese, Jr.R.V.6
-
187
-
-
1642523683
-
Lipopenia and skin barrier abnormalities in DGAT2-deficient mice
-
DOI 10.1074/jbc.M311000200
-
S.J. Stone, H.M. Myers, S.M. Watkins, B.E. Brown, K.R. Feingold, P.M. Elias, and R.V. Farese Jr. Lipopenia and skin barrier abnormalities in DGAT2-deficient mice J. Biol. Chem. 279 2004 11767 11776 (Pubitemid 38401682)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.12
, pp. 11767-11776
-
-
Stone, S.J.1
Myers, H.M.2
Watkins, S.M.3
Brown, B.E.4
Feingold, K.R.5
Elias, P.M.6
Farese Jr., R.V.7
-
188
-
-
0010426032
-
Purification and properties of rat liver microsomal stearyl coenzyme A desaturase
-
P. Strittmatter, L. Spatz, D. Corcoran, M.J. Rogers, B. Setlow, and R. Redline Purification and properties of rat liver microsomal stearyl coenzyme A desaturase Proc. Natl. Acad. Sci. U.S.A. 71 1974 4565 4569
-
(1974)
Proc. Natl. Acad. Sci. U.S.A.
, vol.71
, pp. 4565-4569
-
-
Strittmatter, P.1
Spatz, L.2
Corcoran, D.3
Rogers, M.J.4
Setlow, B.5
Redline, R.6
-
189
-
-
67649421649
-
Functional characterization of the human 1-acylglycerol-3-phosphate-O- acyltransferase isoform 10/glycerol-3-phosphate acyltransferase isoform 3
-
S. Sukumaran, R.I. Barnes, A. Garg, and A.K. Agarwal Functional characterization of the human 1-acylglycerol-3-phosphate-O-acyltransferase isoform 10/glycerol-3-phosphate acyltransferase isoform 3 J. Mol. Endocrinol. 42 2009 469 478
-
(2009)
J. Mol. Endocrinol.
, vol.42
, pp. 469-478
-
-
Sukumaran, S.1
Barnes, R.I.2
Garg, A.3
Agarwal, A.K.4
-
190
-
-
0141737105
-
Crystal structure of the heterodimeric complex of LXRα and RXRβ ligand-binding domains in a fully agonistic conformation
-
DOI 10.1093/emboj/cdg456
-
S. Svensson, T. Ostberg, M. Jacobsson, C. Norstrom, K. Stefansson, D. Hallen, I.C. Johansson, K. Zachrisson, D. Ogg, and L. Jendeberg Crystal structure of the heterodimeric complex of LXRalpha and RXRbeta ligand-binding domains in a fully agonistic conformation EMBO J. 22 2003 4625 4633 (Pubitemid 37162899)
-
(2003)
EMBO Journal
, vol.22
, Issue.18
, pp. 4625-4633
-
-
Svensson, S.1
Ostberg, T.2
Jacobsson, M.3
Norstrom, C.4
Stefansson, K.5
Hallen, D.6
Johansson, I.C.7
Zachrisson, K.8
Ogg, D.9
Jendeberg, L.10
-
191
-
-
0040799893
-
Identification of conserved cis-elements and transcription factors required for sterol-regulated transcription of stearoyl-CoA desaturase 1 and 2
-
D.E. Tabor, J.B. Kim, B.M. Spiegelman, and P.A. Edwards Identification of conserved cis-elements and transcription factors required for sterol-regulated transcription of stearoyl-CoA desaturase 1 and 2 J. Biol. Chem. 274 1999 20603 20610
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 20603-20610
-
-
Tabor, D.E.1
Kim, J.B.2
Spiegelman, B.M.3
Edwards, P.A.4
-
192
-
-
77951218102
-
Polyunsaturated fatty acids selectively suppress sterol regulatory element-binding protein-1 through proteolytic processing and autoloop regulatory circuit
-
Y. Takeuchi, N. Yahagi, Y. Izumida, M. Nishi, M. Kubota, Y. Teraoka, T. Yamamoto, T. Matsuzaka, Y. Nakagawa, M. Sekiya, Y. Iizuka, K. Ohashi, J. Osuga, T. Gotoda, S. Ishibashi, K. Itaka, K. Kataoka, R. Nagai, N. Yamada, T. Kadowaki, and H. Shimano Polyunsaturated fatty acids selectively suppress sterol regulatory element-binding protein-1 through proteolytic processing and autoloop regulatory circuit J. Biol. Chem. 285 2010 11681 11691
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 11681-11691
-
-
Takeuchi, Y.1
Yahagi, N.2
Izumida, Y.3
Nishi, M.4
Kubota, M.5
Teraoka, Y.6
Yamamoto, T.7
Matsuzaka, T.8
Nakagawa, Y.9
Sekiya, M.10
Iizuka, Y.11
Ohashi, K.12
Osuga, J.13
Gotoda, T.14
Ishibashi, S.15
Itaka, K.16
Kataoka, K.17
Nagai, R.18
Yamada, N.19
Kadowaki, T.20
Shimano, H.21
more..
-
193
-
-
33845586243
-
The mechanism mediating the activation of acetyl-coenzyme A carboxylase-α gene transcription by the liver X receptor agonist T0-901317
-
DOI 10.1194/jlr.M600276-JLR200
-
S. Talukdar, and F.B. Hillgartner The mechanism mediating the activation of acetyl-coenzyme A carboxylase-alpha gene transcription by the liver X receptor agonist T0-901317 J. Lipid Res. 47 2006 2451 2461 (Pubitemid 44936107)
-
(2006)
Journal of Lipid Research
, vol.47
, Issue.11
, pp. 2451-2461
-
-
Talukdar, S.1
Hillgartner, F.B.2
-
194
-
-
33750813851
-
Identification of a novel human lysophosphatidic acid acyltransferase, LPAAT-theta, which activates mTOR pathway
-
W. Tang, J. Yuan, X. Chen, X. Gu, K. Luo, J. Li, B. Wan, Y. Wang, and L. Yu Identification of a novel human lysophosphatidic acid acyltransferase, LPAAT-theta, which activates mTOR pathway J. Biochem. Mol. Biol. 39 2006 626 635 (Pubitemid 44714544)
-
(2006)
Journal of Biochemistry and Molecular Biology
, vol.39
, Issue.5
, pp. 626-635
-
-
Tang, W.1
Yuan, J.2
Chen, X.3
Gu, X.4
Luo, K.5
Li, J.6
Wan, B.7
Wang, Y.8
Yu, L.9
-
195
-
-
0023000290
-
24,25-epoxysterol metabolism in cultured mammalian cells and repression of 3-hydroxy-3-methylglutaryl-CoA reductase
-
F.R. Taylor, A.A. Kandutsch, A.K. Gayen, J.A. Nelson, S.S. Nelson, S. Phirwa, and T.A. Spencer 24,25-Epoxysterol metabolism in cultured mammalian cells and repression of 3-hydroxy-3-methylglutaryl-CoA reductase J. Biol. Chem. 261 1986 15039 15044 (Pubitemid 17218070)
-
(1986)
Journal of Biological Chemistry
, vol.261
, Issue.32
, pp. 15039-15044
-
-
Taylor, F.R.1
Kandutsch, A.A.2
Gayen, A.K.3
-
196
-
-
0028918963
-
OR-1, a member of the nuclear receptor superfamily that interacts with the 9-cis-retinoic acid receptor
-
M. Teboul, E. Enmark, Q. Li, A.C. Wikstrom, M. Pelto-Huikko, and J.A. Gustafsson OR-1, a member of the nuclear receptor superfamily that interacts with the 9-cis-retinoic acid receptor Proc. Natl. Acad. Sci. U.S.A. 92 1995 2096 2100
-
(1995)
Proc. Natl. Acad. Sci. U.S.A.
, vol.92
, pp. 2096-2100
-
-
Teboul, M.1
Enmark, E.2
Li, Q.3
Wikstrom, A.C.4
Pelto-Huikko, M.5
Gustafsson, J.A.6
-
197
-
-
0037155935
-
Liver X receptors as insulin-mediating factors in fatty acid and cholesterol biosynthesis
-
DOI 10.1074/jbc.M109771200
-
K.A. Tobin, S.M. Ulven, G.U. Schuster, H.H. Steineger, S.M. Andresen, J.A. Gustafsson, and H.I. Nebb Liver X receptors as insulin-mediating factors in fatty acid and cholesterol biosynthesis J. Biol. Chem. 277 2002 10691 10697 (Pubitemid 34975649)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.12
, pp. 10691-10697
-
-
Biosynthesis, C.1
Tobin, K.A.R.2
Ulven, S.M.3
Schuster, G.U.4
Steineger, H.H.5
Andresen, S.M.6
Gustafsson, J.-A.7
Nebb, H.I.8
-
198
-
-
33645519616
-
Agpat6 deficiency causes subdermal lipodystrophy and resistance to obesity
-
L. Vergnes, A.P. Beigneux, R. Davis, S.M. Watkins, S.G. Young, and K. Reue Agpat6 deficiency causes subdermal lipodystrophy and resistance to obesity J. Lipid Res. 47 2006 745 754
-
(2006)
J. Lipid Res.
, vol.47
, pp. 745-754
-
-
Vergnes, L.1
Beigneux, A.P.2
Davis, R.3
Watkins, S.M.4
Young, S.G.5
Reue, K.6
-
199
-
-
78651354102
-
Targeting liver X receptors in human health: Deadlock or promising trail?
-
E. Viennois, A.J. Pommier, K. Mouzat, A. Oumeddour, F.Z. El Hajjaji, J. Dufour, F. Caira, D.H. Volle, S. Baron, and J.M. Lobaccaro Targeting liver X receptors in human health: deadlock or promising trail? Expert Opin. Ther. Targets 15 2011 219 232
-
(2011)
Expert Opin. Ther. Targets
, vol.15
, pp. 219-232
-
-
Viennois, E.1
Pommier, A.J.2
Mouzat, K.3
Oumeddour, A.4
El Hajjaji, F.Z.5
Dufour, J.6
Caira, F.7
Volle, D.H.8
Baron, S.9
Lobaccaro, J.M.10
-
200
-
-
73849096869
-
Tumor-mediated liver X receptor-alpha activation inhibits CC chemokine receptor-7 expression on dendritic cells and dampens antitumor responses
-
E.J. Villablanca, L. Raccosta, D. Zhou, R. Fontana, D. Maggioni, A. Negro, F. Sanvito, M. Ponzoni, B. Valentinis, M. Bregni, A. Prinetti, K.R. Steffensen, S. Sonnino, J.A. Gustafsson, C. Doglioni, C. Bordignon, C. Traversari, and V. Russo Tumor-mediated liver X receptor-alpha activation inhibits CC chemokine receptor-7 expression on dendritic cells and dampens antitumor responses Nat. Med. 16 2010 98 105
-
(2010)
Nat. Med.
, vol.16
, pp. 98-105
-
-
Villablanca, E.J.1
Raccosta, L.2
Zhou, D.3
Fontana, R.4
Maggioni, D.5
Negro, A.6
Sanvito, F.7
Ponzoni, M.8
Valentinis, B.9
Bregni, M.10
Prinetti, A.11
Steffensen, K.R.12
Sonnino, S.13
Gustafsson, J.A.14
Doglioni, C.15
Bordignon, C.16
Traversari, C.17
Russo, V.18
-
201
-
-
34250805279
-
Multiple roles of the nuclear receptors for oxysterols liver X receptor to maintain male fertility
-
DOI 10.1210/me.2006-0277
-
D.H. Volle, K. Mouzat, R. Duggavathi, B. Siddeek, P. Dechelotte, B. Sion, G. Veyssiere, M. Benahmed, and J.M. Lobaccaro Multiple roles of the nuclear receptors for oxysterols liver X receptor to maintain male fertility Mol. Endocrinol. 21 2007 1014 1027 (Pubitemid 46984755)
-
(2007)
Molecular Endocrinology
, vol.21
, Issue.5
, pp. 1014-1027
-
-
Volle, D.H.1
Mouzat, K.2
Duggavathi, R.3
Siddeek, B.4
Dechelotte, P.5
Sion, B.6
Veyssiere, G.7
Benahmed, M.8
Lobaccaro, J.-M.A.9
-
202
-
-
34548390652
-
Cloning and functional characterization of a novel mitochondrial N-ethylmaleimide-sensitive glycerol-3-phosphate acyltransferase (GPAT2)
-
DOI 10.1016/j.abb.2007.06.033, PII S0003986107002974
-
S. Wang, D.P. Lee, N. Gong, N.M. Schwerbrock, D.G. Mashek, M.R. Gonzalez-Baro, C. Stapleton, L.O. Li, T.M. Lewin, and R.A. Coleman Cloning and functional characterization of a novel mitochondrial N-ethylmaleimide-sensitive glycerol-3-phosphate acyltransferase (GPAT2) Arch. Biochem. Biophys. 465 2007 347 358 (Pubitemid 47361998)
-
(2007)
Archives of Biochemistry and Biophysics
, vol.465
, Issue.2
, pp. 347-358
-
-
Wang, S.1
Lee, D.P.2
Gong, N.3
Schwerbrock, N.M.J.4
Mashek, D.G.5
Gonzalez-Baro, M.R.6
Stapleton, C.7
Li, L.O.8
Lewin, T.M.9
Coleman, R.A.10
-
203
-
-
0028225462
-
SREBP-1, a membrane-bound transcription factor released by sterol-regulated proteolysis
-
X. Wang, R. Sato, M.S. Brown, X. Hua, and J.L. Goldstein SREBP-1, a membrane-bound transcription factor released by sterol-regulated proteolysis Cell 77 1994 53 62
-
(1994)
Cell
, vol.77
, pp. 53-62
-
-
Wang, X.1
Sato, R.2
Brown, M.S.3
Hua, X.4
Goldstein, J.L.5
-
204
-
-
0029035278
-
LXR, a nuclear receptor that defines a distinct retinoid response pathway
-
P.J. Willy, K. Umesono, E.S. Ong, R.M. Evans, R.A. Heyman, and D.J. Mangelsdorf LXR, a nuclear receptor that defines a distinct retinoid response pathway Genes Dev. 9 1995 1033 1045
-
(1995)
Genes Dev.
, vol.9
, pp. 1033-1045
-
-
Willy, P.J.1
Umesono, K.2
Ong, E.S.3
Evans, R.M.4
Heyman, R.A.5
Mangelsdorf, D.J.6
-
205
-
-
10644229420
-
Statins inhibit synthesis of an oxysterol ligand for the liver X receptor in human macrophages with consequences for cholesterol flux
-
DOI 10.1161/01.ATV.0000148707.93054.7d
-
J. Wong, C.M. Quinn, and A.J. Brown Statins inhibit synthesis of an oxysterol ligand for the liver X receptor in human macrophages with consequences for cholesterol flux Arterioscler. Thromb. Vasc. Biol. 24 2004 2365 2371 (Pubitemid 39658043)
-
(2004)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.24
, Issue.12
, pp. 2365-2371
-
-
Wong, J.1
Quinn, C.M.2
Brown, A.J.3
-
206
-
-
33845748205
-
SREBP-2 positively regulates transcription of the cholesterol efflux gene, ABCA1, by generating oxysterol ligands for LXR
-
DOI 10.1042/BJ20060914
-
J. Wong, C.M. Quinn, and A.J. Brown SREBP-2 positively regulates transcription of the cholesterol efflux gene, ABCA1, by generating oxysterol ligands for LXR Biochem. J. 400 2006 485 491 (Pubitemid 44974460)
-
(2006)
Biochemical Journal
, vol.400
, Issue.3
, pp. 485-491
-
-
Wong, J.1
Quinn, C.M.2
Brown, A.J.3
-
207
-
-
34247381583
-
Synthesis of the oxysterol, 24(S), 25-epoxycholesterol, parallels cholesterol production and may protect against cellular accumulation of newly-synthesized cholesterol
-
J. Wong, C.M. Quinn, and A.J. Brown Synthesis of the oxysterol, 24(S), 25-epoxycholesterol, parallels cholesterol production and may protect against cellular accumulation of newly-synthesized cholesterol Lipids Health Dis. 6 2007 10
-
(2007)
Lipids Health Dis.
, vol.6
, pp. 10
-
-
Wong, J.1
Quinn, C.M.2
Brown, A.J.3
-
208
-
-
38149138153
-
Endogenous 24(S),25-epoxycholesterol fine-tunes acute control of cellular cholesterol homeostasis
-
J. Wong, C.M. Quinn, I.C. Gelissen, and A.J. Brown Endogenous 24(S),25-epoxycholesterol fine-tunes acute control of cellular cholesterol homeostasis J. Biol. Chem. 283 2008 700 707
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 700-707
-
-
Wong, J.1
Quinn, C.M.2
Gelissen, I.C.3
Brown, A.J.4
-
209
-
-
38049081038
-
The effect of statins on ABCA1 and ABCG1 expression in human macrophages is influenced by cellular cholesterol levels and extent of differentiation
-
J. Wong, C.M. Quinn, I.C. Gelissen, W. Jessup, and A.J. Brown The effect of statins on ABCA1 and ABCG1 expression in human macrophages is influenced by cellular cholesterol levels and extent of differentiation Atherosclerosis 196 2008 180 189
-
(2008)
Atherosclerosis
, vol.196
, pp. 180-189
-
-
Wong, J.1
Quinn, C.M.2
Gelissen, I.C.3
Jessup, W.4
Brown, A.J.5
-
210
-
-
33748323244
-
Hepatic knockdown of mitochondrial GPAT1 in ob/ob mice improves metabolic profile
-
DOI 10.1016/j.bbrc.2006.08.071, PII S0006291X06018742
-
H. Xu, D. Wilcox, P. Nguyen, M. Voorbach, T. Suhar, S.J. Morgan, W.F. An, L. Ge, J. Green, Z. Wu, R.E. Gimeno, R. Reilly, P.B. Jacobson, C.A. Collins, K. Landschulz, and T. Surowy Hepatic knockdown of mitochondrial GPAT1 in ob/ob mice improves metabolic profile Biochem. Biophys. Res. Commun. 349 2006 439 448 (Pubitemid 44331810)
-
(2006)
Biochemical and Biophysical Research Communications
, vol.349
, Issue.1
, pp. 439-448
-
-
Xu, H.1
Wilcox, D.2
Nguyen, P.3
Voorbach, M.4
Suhar, T.5
Morgan, S.J.6
An, W.F.7
Ge, L.8
Green, J.9
Wu, Z.10
Gimeno, R.E.11
Reilly, R.12
Jacobson, P.B.13
Collins, C.A.14
Landschulz, K.15
Surowy, T.16
-
211
-
-
77957558615
-
Regulation of hepatocyte lipid metabolism and inflammatory response by 25-hydroxycholesterol and 25-hydroxycholesterol-3-sulfate
-
L. Xu, Q. Bai, D. Rodriguez-Agudo, P.B. Hylemon, D.M. Heuman, W.M. Pandak, and S. Ren Regulation of hepatocyte lipid metabolism and inflammatory response by 25-hydroxycholesterol and 25-hydroxycholesterol-3-sulfate Lipids 45 2010 821 832
-
(2010)
Lipids
, vol.45
, pp. 821-832
-
-
Xu, L.1
Bai, Q.2
Rodriguez-Agudo, D.3
Hylemon, P.B.4
Heuman, D.M.5
Pandak, W.M.6
Ren, S.7
-
212
-
-
0037453007
-
Liver-specific mRNA for insig-2 down-regulated by insulin: Implications for fatty acid synthesis
-
DOI 10.1073/pnas.0130116100
-
D. Yabe, R. Komuro, G. Liang, J.L. Goldstein, and M.S. Brown Liver-specific mRNA for Insig-2 down-regulated by insulin: implications for fatty acid synthesis Proc. Natl. Acad. Sci. U.S.A. 100 2003 3155 3160 (Pubitemid 36356555)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.6
, pp. 3155-3160
-
-
Yabe, D.1
Komuro, R.2
Liang, G.3
Goldstein, J.L.4
Brown, M.S.5
-
213
-
-
34249721531
-
Protein kinase A suppresses sterol regulatory element-binding protein-1C expression via phosphorylation of liver X receptor in the liver
-
DOI 10.1074/jbc.M611911200
-
T. Yamamoto, H. Shimano, N. Inoue, Y. Nakagawa, T. Matsuzaka, A. Takahashi, N. Yahagi, H. Sone, H. Suzuki, H. Toyoshima, and N. Yamada Protein kinase A suppresses sterol regulatory element-binding protein-1C expression via phosphorylation of liver X receptor in the liver J. Biol. Chem. 282 2007 11687 11695 (Pubitemid 47100691)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.16
, pp. 11687-11695
-
-
Yamamoto, T.1
Shimano, H.2
Inoue, N.3
Nakagawa, Y.4
Matsuzaka, T.5
Takahashi, A.6
Yahagi, N.7
Sone, H.8
Suzuki, H.9
Toyoshima, H.10
Yamada, N.11
-
214
-
-
0035979214
-
A glucose-responsive transcription factor that regulates carbohydrate metabolism in the liver
-
DOI 10.1073/pnas.161284298
-
H. Yamashita, M. Takenoshita, M. Sakurai, R.K. Bruick, W.J. Henzel, W. Shillinglaw, D. Arnot, and K. Uyeda A glucose-responsive transcription factor that regulates carbohydrate metabolism in the liver Proc. Natl. Acad. Sci. U.S.A. 98 2001 9116 9121 (Pubitemid 32743878)
-
(2001)
Proceedings of the National Academy of Sciences of the United States of America
, vol.98
, Issue.16
, pp. 9116-9121
-
-
Yamashita, H.1
Takenoshita, M.2
Sakurai, M.3
Bruick, R.K.4
Henzel, W.J.5
Shillinglaw, W.6
Arnot, D.7
Uyeda, K.8
-
215
-
-
77950911589
-
Tissue-specific liver X receptor activation promotes macrophage reverse cholesterol transport in vivo
-
T. Yasuda, D. Grillot, J.T. Billheimer, F. Briand, P. Delerive, S. Huet, and D.J. Rader Tissue-specific liver X receptor activation promotes macrophage reverse cholesterol transport in vivo Arterioscler. Thromb. Vasc. Biol. 30 2010 781 786
-
(2010)
Arterioscler. Thromb. Vasc. Biol.
, vol.30
, pp. 781-786
-
-
Yasuda, T.1
Grillot, D.2
Billheimer, J.T.3
Briand, F.4
Delerive, P.5
Huet, S.6
Rader, D.J.7
-
216
-
-
33645242416
-
Cloning and characterization a novel human 1-acyl-sn-glycerol-3-phosphate acyltransferase gene AGPAT7
-
DOI 10.1080/10425170500213712, PII L1074747Q1406671
-
G.M. Ye, C. Chen, S. Huang, D.D. Han, J.H. Guo, B. Wan, and L. Yu Cloning and characterization a novel human 1-acyl-sn-glycerol-3-phosphate acyltransferase gene AGPAT7 DNA Seq. 16 2005 386 390 (Pubitemid 44567645)
-
(2005)
DNA Sequence - Journal of DNA Sequencing and Mapping
, vol.16
, Issue.5
, pp. 386-390
-
-
Ye, G.-M.1
Chen, C.2
Huang, S.3
Han, D.-D.4
Guo, J.-H.5
Wan, B.6
Yu, L.7
-
217
-
-
0027490174
-
SREBP-1, a basic-helix-loop-helix-leucine zipper protein that controls transcription of the low density lipoprotein receptor gene
-
DOI 10.1016/0092-8674(93)90690-R
-
C. Yokoyama, X. Wang, M.R. Briggs, A. Admon, J. Wu, X. Hua, J.L. Goldstein, and M.S. Brown SREBP-1, a basic-helix-loop-helix-leucine zipper protein that controls transcription of the low density lipoprotein receptor gene Cell 75 1993 187 197 (Pubitemid 23306032)
-
(1993)
Cell
, vol.75
, Issue.1
, pp. 187-197
-
-
Yokoyama, C.1
Wang, X.2
Briggs, M.R.3
Admon, A.4
Wu, J.5
Hua, X.6
Goldstein, J.L.7
Brown, M.S.8
-
218
-
-
34547531201
-
Attenuation of neuroinflammation and Alzheimer's disease pathology by liver x receptors
-
DOI 10.1073/pnas.0701096104
-
N. Zelcer, N. Khanlou, R. Clare, Q. Jiang, E.G. Reed-Geaghan, G.E. Landreth, H.V. Vinters, and P. Tontonoz Attenuation of neuroinflammation and Alzheimer's disease pathology by liver X receptors Proc. Natl. Acad. Sci. U.S.A. 104 2007 10601 10606 (Pubitemid 47185711)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.25
, pp. 10601-10606
-
-
Zelcer, N.1
Khanlou, N.2
Clare, R.3
Jiang, Q.4
Reed-Geaghan, E.G.5
Landreth, G.E.6
Vinters, H.V.7
Tontonoz, P.8
-
219
-
-
33644651160
-
Liver X receptors as integrators of metabolic and inflammatory signaling
-
DOI 10.1172/JCI27883
-
N. Zelcer, and P. Tontonoz Liver X receptors as integrators of metabolic and inflammatory signaling J. Clin. Invest. 116 2006 607 614 (Pubitemid 43326865)
-
(2006)
Journal of Clinical Investigation
, vol.116
, Issue.3
, pp. 607-614
-
-
Zelcer, N.1
Tontonoz, P.2
-
220
-
-
33744515637
-
FoxO1 regulates multiple metabolic pathways in the liver effects on gluconeogenic, glycolytic, and lipogenic gene expression
-
DOI 10.1074/jbc.M600272200
-
W. Zhang, S. Patil, B. Chauhan, S. Guo, D.R. Powell, J. Le, A. Klotsas, R. Matika, X. Xiao, R. Franks, K.A. Heidenreich, M.P. Sajan, R.V. Farese, D.B. Stolz, P. Tso, S.H. Koo, M. Montminy, and T.G. Unterman FoxO1 regulates multiple metabolic pathways in the liver: effects on gluconeogenic, glycolytic, and lipogenic gene expression J. Biol. Chem. 281 2006 10105 10117 (Pubitemid 43864546)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.15
, pp. 10105-10117
-
-
Zhang, W.1
Patil, S.2
Chauhan, B.3
Guo, S.4
Powell, D.R.5
Le, J.6
Klotsas, A.7
Matika, R.8
Xiao, X.9
Franks, R.10
Heidenreich, K.A.11
Sajan, M.P.12
Farese, R.V.13
Stolz, D.B.14
Tso, P.15
Koo, S.-H.16
Montminy, M.17
Unterman, T.G.18
-
221
-
-
0035862555
-
Scd3 - A novel gene of the stearoyl-CoA desaturase family with restricted expression in skin
-
DOI 10.1006/geno.2000.6429
-
Y. Zheng, S.M. Prouty, A. Harmon, J.P. Sundberg, K.S. Stenn, and S. Parimoo Scd3-a novel gene of the stearoyl-CoA desaturase family with restricted expression in skin Genomics 71 2001 182 191 (Pubitemid 32165085)
-
(2001)
Genomics
, vol.71
, Issue.2
, pp. 182-191
-
-
Zheng, Y.1
Prouty, S.M.2
Harmon, A.3
Sundberg, J.P.4
Stenn, K.S.5
Parimoo, S.6
|