Stimulation of lipogenesis by pharmacological activation of the liver X receptor leads to production of large, triglyceride-rich very low density lipoprotein particles

Journal of Biological Chemistry

Volumn 277, Issue 37, 2002, Pages 34182-34190

  Grefhorst, Aldo ^a,b,c,d   Elzinga, Baukje M ^a,b,c,d   Voshol, Peter J ^a,b,c,d   Plösch, Torsten ^a,b,c,d   Kok, Tineke ^a,b,c,d   Bloks, Vincent W ^a,b,c,d   Van Der Sluijs, Fjodor H ^a,b,c,d   Havekes, Louis M ^a,b,c,d   Romijn, Johannes A ^a,b,c,d   Verkade, Henkjan J ^a,b,c,d   Kuipers, Folkert ^a,b,c,d  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^b TNO   (Netherlands)

^c Department of Endocrinology and Diabetes ^*  (Netherlands)

^d LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

PHARMACOLOGICAL ACTIVATION;

CELLS; FATTY ACIDS; GENES; METABOLISM;

BIOCHEMISTRY;

APOLIPOPROTEIN E3; CELL NUCLEUS RECEPTOR; LIVER X RECEPTOR; OXYSTEROL; STEROL; STEROL REGULATORY ELEMENT BINDING PROTEIN; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; VERY LOW DENSITY LIPOPROTEIN;

ACC1 GENE; AGONIST; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ATHEROGENESIS; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; FAS GENE; FATTY ACID METABOLISM; FATTY LIVER; GENE; GENE INDUCTION; GENETIC TRANSCRIPTION; HYPERTRIGLYCERIDEMIA; KNOCKOUT MOUSE; LIPOGENESIS; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; TRANSACTIVATION; TRIACYLGLYCEROL BLOOD LEVEL;

ANIMALS; ANTICHOLESTEREMIC AGENTS; APOLIPOPROTEINS E; CARRIER PROTEINS; CELL LINE; DNA-BINDING PROTEINS; HYPERTRIGLYCERIDEMIA; LIPIDS; LIPOPROTEINS, VLDL; LIVER; MALE; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; PHOSPHOLIPID TRANSFER PROTEINS; RATS; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECEPTORS, LDL; RECEPTORS, RETINOIC ACID; RECEPTORS, THYROID HORMONE; SULFONAMIDES; TRIGLYCERIDES;

ANIMALIA; MUS MUSCULUS;

EID: 0037072732     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M204887200     Document Type: Article

References (50)