-
1
-
-
0035976638
-
Nuclear receptors and lipid physiology: Opening the x-files
-
DOI 10.1126/science.294.5548.1866
-
Chawla A, Repa JJ, Evans RM, et al. Nuclear receptors and lipid physiology: opening the X-files. Science. 2001;294(5548):1866-1870. (Pubitemid 33101573)
-
(2001)
Science
, vol.294
, Issue.5548
, pp. 1866-1870
-
-
Chawta, A.1
Repa, J.J.2
Evans, R.M.3
Mangelsdorf, D.J.4
-
2
-
-
14444285707
-
Activation of the nuclear receptor LXR by oxysterols defines a new hormone response pathway
-
DOI 10.1074/jbc.272.6.3137
-
Lehmann JM, Kliewer SA, Moore LB, et al. Activation of the nuclear receptor LXR by oxysterols defines a new hormone response pathway. J Biol Chem. 1997;272(6):3137-3140. (Pubitemid 27066798)
-
(1997)
Journal of Biological Chemistry
, vol.272
, Issue.6
, pp. 3137-3140
-
-
Lehmann, J.M.1
Kliewer, S.A.2
Moore, L.B.3
Smith-Oliver, T.A.4
Oliver, B.B.5
Su, J.-L.6
Sundseth, S.S.7
Winegar, D.A.8
Blanchard, D.E.9
Spencer, T.A.10
Willson, T.M.11
-
3
-
-
0013199471
-
Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXRalpha
-
DOI 10.1016/S0092-8674(00)81432-4
-
Peet DJ, Turley SD, Ma W, et al. Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXR alpha. Cell. 1998;93(5):693-704. (Pubitemid 28257577)
-
(1998)
Cell
, vol.93
, Issue.5
, pp. 693-704
-
-
Peet, D.J.1
Turley, S.D.2
Ma, W.3
Janowski, B.A.4
Lobaccaro, J.-M.A.5
Hammer, R.E.6
Mangelsdorf, D.J.7
-
4
-
-
0034284918
-
Regulation of absorption and ABC1-mediated efflux of cholesterol by RXR heterodimers
-
Repa JJ, Turley SD, Lobaccaro JA, et al. Regulation of absorption and ABC1-mediated efflux of cholesterol by RXR heterodimers. Science. 2000;289(5484):1446-1447.
-
(2000)
Science
, vol.289
, Issue.5484
, pp. 1446-1447
-
-
Repa, J.J.1
Turley, S.D.2
Lobaccaro, J.A.3
-
5
-
-
0035823531
-
Human ABCA1 BAC transgenic mice show increased high density lipoprotein cholesterol and ApoAI-dependent efflux stimulated by an internal promoter containing liver X receptor response elements in intron 1
-
Singaraja RR, Bocher V, James ER, et al. Human ABCA1 BAC transgenic mice show increased high density lipoprotein cholesterol and ApoAI-dependent efflux stimulated by an internal promoter containing liver X receptor response elements in intron 1. J Biol Chem. 2001;276(36):33969-33979.
-
(2001)
J Biol Chem
, vol.276
, Issue.36
, pp. 33969-33979
-
-
Singaraja, R.R.1
Bocher, V.2
James, E.R.3
-
6
-
-
0037166261
-
Regulation of ATP-binding cassette sterol transporters ABCG5 and ABCG8 by the liver X receptors alpha and beta
-
DOI 10.1074/jbc.M109927200
-
Repa JJ, Berge KE, Pomajzl C, et al. Regulation of ATP-binding cassette sterol transporters ABCG5 and ABCG8 by the liver X receptors alpha and beta. J Biol Chem. 2002;277(21):18793-18800. (Pubitemid 34952438)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.21
, pp. 18793-18800
-
-
Repa, J.J.1
Berge, K.E.2
Pomajzl, C.3
Richardson, J.A.4
Hobbs, H.5
Mangelsdorf, D.J.6
-
7
-
-
0037324340
-
Reciprocal regulation of inflammation and lipid metabolism by liver X receptors
-
DOI 10.1038/nm820
-
Joseph SB, Castrillo A, Laffitte BA, et al. Reciprocal regulation of inflammation and lipid metabolism by liver X receptors. Nat Med. 2003;9(2):213-219. (Pubitemid 36227724)
-
(2003)
Nature Medicine
, vol.9
, Issue.2
, pp. 213-219
-
-
Joseph, S.B.1
Castrillo, A.2
Laffitte, B.A.3
Mangelsdorf, D.J.4
Tontonoz, P.5
-
8
-
-
0037289786
-
Liver X receptor activators display anti-inflammatory activity in irritant and allergic contact dermatitis models: Liver-X-receptor-specific inhibition of inflammation and primary cytokine production
-
DOI 10.1046/j.1523-1747.2003.12033.x
-
Fowler AJ, Sheu MY, Schmuth M, et al. Liver X receptor activators display anti-inflammatory activity in irritant and allergic contact dermatitis models: liver-X-receptor-specific inhibition of inflammation and primary cytokine production. J Invest Dermatol. 2003;120(2):246-255. (Pubitemid 36513075)
-
(2003)
Journal of Investigative Dermatology
, vol.120
, Issue.2
, pp. 246-255
-
-
Fowler, A.J.1
Sheu, M.Y.2
Schmuth, M.3
Kao, J.4
Fluhr, J.W.5
Rhein, L.6
Collins, J.L.7
Willson, T.M.8
Mangelsdorf, D.J.9
Elias, P.M.10
Feingold, K.R.11
-
9
-
-
0037188553
-
Synthetic LXR ligand inhibits the development of atherosclerosis in mice
-
Joseph SB, McKilligin E, Pei L, et al. Synthetic LXR ligand inhibits the development of atherosclerosis in mice. Proc Natl Acad Sci U S A. 2002;99(11):76049.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, Issue.11
, pp. 76049
-
-
Joseph, S.B.1
McKilligin, E.2
Pei, L.3
-
10
-
-
0037015013
-
Identification of macrophage liver X receptors as inhibitors of atherosclerosis
-
DOI 10.1073/pnas.182199799
-
Tangirala RK, Bischoff ED, Joseph SB, et al. Identification of macrophage liver X receptors as inhibitors of atherosclerosis. Proc Natl Acad Sci U S A. 2002;99(18):11896-11901. (Pubitemid 34994495)
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, Issue.18
, pp. 11896-11901
-
-
Tangirala, R.K.1
Bischoff, E.D.2
Joseph, S.B.3
Wagner, B.L.4
Walczak, R.5
Laffitte, B.A.6
Daige, C.L.7
Thomas, D.8
Heyman, R.A.9
Mangelsdorf, D.J.10
Wang, X.11
Lusis, A.J.12
Tontonoz, P.13
Schulman, I.G.14
-
11
-
-
2942546273
-
Release of soluble CD40L from platelets is regulated by glycoprotein IIb/IIIa and actin polymerization
-
DOI 10.1016/j.jacc.2003.12.055, PII S0735109704005868
-
Furman MI, Krueger LA, Linden MD, et al. Release of soluble CD40L from platelets is regulated by glycoprotein IIb/IIIa and actin polymerization. J Am Coll Cardiol. 2004;43(12):2319-2325. (Pubitemid 38757605)
-
(2004)
Journal of the American College of Cardiology
, vol.43
, Issue.12
, pp. 2319-2325
-
-
Furman, M.I.1
Krueger, L.A.2
Linden, M.D.3
Barnard, M.R.4
Frelinger III, A.L.5
Michelson, A.D.6
-
12
-
-
0037097809
-
Endothelial von Willebrand factor recruits platelets to atherosclerosis-prone sites in response to hypercholesterolemia
-
DOI 10.1182/blood.V99.12.4486
-
Theilmeier G, Michiels C, Spaepen E, et al. Endothelial von Willebrand factor recruits platelets to atherosclerosis-prone sites in response to hypercholesterolemia. Blood. 2002;99(12):4486-4493. (Pubitemid 34627218)
-
(2002)
Blood
, vol.99
, Issue.12
, pp. 4486-4493
-
-
Theilmeier, G.1
Michiels, C.2
Spaepen, E.3
Vreys, I.4
Collen, D.5
Vermylen, J.6
Hoylaerts, M.F.7
-
13
-
-
0029119149
-
Platelets roll on stimulated endothelium in vivo: An interaction mediated by endothelial P-selectin
-
Frenette PS, Johnson RC, Hynes RO, et al. Platelets roll on stimulated endothelium in vivo: an interaction mediated by endothelial P-selectin. Proc Natl Acad Sci U S A. 1995;92(16):7450-7454.
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, Issue.16
, pp. 7450-7454
-
-
Frenette, P.S.1
Johnson, R.C.2
Hynes, R.O.3
-
14
-
-
0035817627
-
Activated platelets mediate inflammatory signaling by regulated interleukin 1beta synthesis
-
DOI 10.1083/jcb.200105058
-
Lindemann S, Tolley ND, Dixon DA. Activated platelets mediate inflammatory signaling by regulated interleukin 1beta synthesis. J Cell Biol. 2001;154(3):485-490. (Pubitemid 34286155)
-
(2001)
Journal of Cell Biology
, vol.154
, Issue.3
, pp. 485-490
-
-
Lindemann, S.1
Tolley, N.D.2
Dixon, D.A.3
McIntyre, T.M.4
Prescott, S.M.5
Zimmerman, G.A.6
Weyrich, A.S.7
-
15
-
-
75949128633
-
Antiplatelet therapies for the treatment of cardiovascular disease
-
Michelson AD. Antiplatelet therapies for the treatment of cardiovascular disease. Nat Rev Drug Discov. 2010;9(2):154-169.
-
(2010)
Nat Rev Drug Discov
, vol.9
, Issue.2
, pp. 154-169
-
-
Michelson, A.D.1
-
17
-
-
65549087101
-
Antiplatelet actions of statins and fibrates are mediated by PPARs
-
Ali FY, Armstrong PC, Dhanji AR, et al. Antiplatelet actions of statins and fibrates are mediated by PPARs. Arterioscler Thromb Vasc Biol. 2009;29(5):706-701.
-
(2009)
Arterioscler Thromb Vasc Biol
, vol.29
, Issue.5
, pp. 706-1701
-
-
Ali, F.Y.1
Armstrong, P.C.2
Dhanji, A.R.3
-
18
-
-
77951716673
-
Basic science review. Statin therapy: I. The pleiotropic effects of statins in cardiovascular disease
-
Sadowitz B, Maier KG, Gahtan V. Basic science review. Statin therapy: I. The pleiotropic effects of statins in cardiovascular disease. Vasc Endovascular Surg. 2010;44(4):241-245.
-
(2010)
Vasc Endovascular Surg
, vol.44
, Issue.4
, pp. 241-245
-
-
Sadowitz, B.1
Maier, K.G.2
Gahtan, V.3
-
19
-
-
0342316532
-
Oxysterols: Modulators of cholesterol metabolism and other processes
-
Schroepfer GJ Jr. Oxysterols: modulators of cholesterol metabolism and other processes. Physiol Rev. 2000;80(1):361-365.
-
(2000)
Physiol Rev
, vol.80
, Issue.1
, pp. 361-365
-
-
Schroepfer Jr., G.J.1
-
20
-
-
13344295095
-
Initiation of platelet adhesion by arrest onto fibrinogen or translocation on von Willebrand factor
-
DOI 10.1016/S0092-8674(00)80983-6
-
Savage B, Saldivar E, Ruggeri ZM. Initiation of platelet adhesion by arrest onto fibrinogen or translocation on von Willebrand factor. Cell. 1996;84(2):289-297. (Pubitemid 26040846)
-
(1996)
Cell
, vol.84
, Issue.2
, pp. 289-297
-
-
Savage, B.1
Saldivar, E.2
Ruggeri, Z.M.3
-
21
-
-
0030790042
-
Glycoprotein VI is the collagen receptor in platelets which underlies tyrosine phosphorylation of the Fc receptor gamma-chain
-
DOI 10.1016/S0014-5793(97)00926-5, PII S0014579397009265
-
Gibbins JM, Okuma M, Farndale R, et al. Glycoprotein VI is the collagen receptor in platelets which underlies tyrosine phosphorylation of the Fc receptor gamma-chain. FEBS Lett. 1997;413(2):255-259. (Pubitemid 27353279)
-
(1997)
FEBS Letters
, vol.413
, Issue.2
, pp. 255-259
-
-
Gibbins, J.M.1
Okuma, M.2
Farndale, R.3
Barnes, M.4
Watson, S.P.5
-
22
-
-
0030764155
-
A novel association of Fc receptor gamma-chain with glycoprotein VI and their co-expression as a collagen receptor in human platelets
-
DOI 10.1074/jbc.272.38.23528
-
Tsuji M, Ezumi Y, Arai M, Takayama H. A novel association of Fc receptor gamma-chain with glycoprotein VI and their co-expression as a collagen receptor in human platelets. J Biol Chem. 1997;272(38):23528-23531. (Pubitemid 27410920)
-
(1997)
Journal of Biological Chemistry
, vol.272
, Issue.38
, pp. 23528-23531
-
-
Tsuji, M.1
Ezumi, Y.2
Arai, M.3
Takayama, H.4
-
23
-
-
0037077263
-
Association of Fyn and Lyn with the proline-rich domain of glycoprotein VI regulates intracellular signaling
-
DOI 10.1074/jbc.M201012200
-
Suzuki-Inoue K, Tulasne D, Shen Y, et al. Association of Fyn and Lyn with the proline-rich domain of glycoprotein VI regulates intracellular signaling. J Biol Chem. 2002;277(24):21561-21566. (Pubitemid 34952302)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.24
, pp. 21561-21566
-
-
Suzuki-Inoue, K.1
Tulasne, D.2
Shen, Y.3
Bori-Sanz, T.4
Inoue, O.5
Jung, S.M.6
Moroi, M.7
Andrews, R.K.8
Berndt, M.C.9
Watson, S.P.10
-
24
-
-
0030917981
-
The Fc receptor gamma-chain and the tyrosine kinase Syk are essential for activation of mouse platelets by collagen
-
DOI 10.1093/emboj/16.9.2333
-
Poole A, Gibbins JM, Turner MJ, et al. The Fc receptor gamma-chain and the tyrosine kinase Syk are essential for activation of mouse platelets by collagen. EMBO J. 1997;16(9):2333-2341. (Pubitemid 27258634)
-
(1997)
EMBO Journal
, vol.16
, Issue.9
, pp. 2333-2341
-
-
Poole, A.1
Gibbins, J.M.2
Turner, M.3
Van Vugt, M.J.4
Van De, W.J.G.J.5
Saito, T.6
Tybulewicz, V.L.J.7
Watson, S.P.8
-
25
-
-
0032545307
-
The p85 subunit of phosphatidylinositol 3-kinase associates with the Fc receptor gamma-chain and linker for activitor of T cells (LAT) in platelets stimulated by collagen and convulxin
-
DOI 10.1074/jbc.273.51.34437
-
Gibbins JM, Briddon S, Shutes A, et al. The p85 subunit of phosphatidylinositol 3-kinase associates with the Fc receptor gamma-chain and linker for activitor of T cells (LAT) in platelets stimulated by collagen and convulxin. J Biol Chem. 1998;273(51):34437-34443. (Pubitemid 29008923)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.51
, pp. 34437-34443
-
-
Gibbins, J.M.1
Briddon, S.2
Shutes, A.3
Van Vugt, M.J.4
Van De, W.J.G.J.5
Saito, T.6
Watson, S.P.7
-
26
-
-
0033605135
-
Tyrosine phosphorylation of SLP-76 is downstream of Syk following stimulation of the collagen receptor in platelets
-
DOI 10.1074/jbc.274.9.5963
-
Gross BS, Lee JR, Clements JL, et al. Tyrosine phosphorylation of SLP-76 is downstream of Syk following stimulation of the collagen receptor in platelets. J Biol Chem. 1999;274(9):5963-5971. (Pubitemid 29109256)
-
(1999)
Journal of Biological Chemistry
, vol.274
, Issue.9
, pp. 5963-5971
-
-
Gross, B.S.1
Lee, J.R.2
Clements, J.L.3
Turner, M.4
Tybulewicz, V.L.J.5
Findell, P.R.6
Koretzky, G.A.7
Watson, S.P.8
-
27
-
-
17644442615
-
Rapid tyrosine phosphorylation and activation of Bruton's tyrosine/Tec kinases in platelets induced by collagen binding or CD32 cross-linking
-
Oda A, Ikeda Y, Ochs HD. Rapid tyrosine phosphorylation and activation of Bruton's tyrosine/Tec kinases in platelets induced by collagen binding or CD32 cross-linking. Blood. 2000;95(5):1663-1670. (Pubitemid 30120827)
-
(2000)
Blood
, vol.95
, Issue.5
, pp. 1663-1670
-
-
Oda, A.1
Ikeda, Y.2
Ochs, H.D.3
Druker, B.J.4
Ozaki, K.5
Handa, M.6
Ariga, T.7
Sakiyama, Y.8
Witte, O.N.9
Wah, M.I.10
-
28
-
-
0031914973
-
Molecular basis for ADP-induced platelet activation: I. Evidence for three distinct ADP receptors on human platelets
-
DOI 10.1074/jbc.273.4.2024
-
Daniel JL, Dangelmaier C, Jin J, et al. Molecular basis for ADP-induced platelet activation: evidence for three distinct ADP receptors on human platelets. J Biol Chem. 1998;273(4):2024-2029. (Pubitemid 28069248)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.4
, pp. 2024-2029
-
-
Daniel, J.L.1
Dangelmaier, C.2
Jin, J.3
Ashby, B.4
Smith, J.B.5
Kunapuli, S.P.6
-
29
-
-
0026072992
-
2 receptor
-
Hirata M, Hayashi Y, Ushikubi F, et al. Cloning and expression of cDNA for a human thromboxane A2 receptor. Nature. 1991;349(6310):617-620. (Pubitemid 21912117)
-
(1991)
Nature
, vol.349
, Issue.6310
, pp. 617-620
-
-
Hirata, M.1
Hayashi, Y.2
Ushikubi, F.3
Yokota, Y.4
Kageyama, R.5
Nakanishi, S.6
Narumiya, S.7
-
30
-
-
0026035523
-
Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation
-
Vu TK, Hung DT, Wheaton VI, et al. Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation. Cell. 1991;64(6):1057-1068. (Pubitemid 121001193)
-
(1991)
Cell
, vol.64
, Issue.6
, pp. 1057-1068
-
-
Vu, T.-K.H.1
Hung, D.T.2
Wheaton, V.I.3
Coughlin, S.R.4
-
31
-
-
11144230882
-
Macrophage liver X receptor is required for antiatherogenic activity of LXR agonists
-
DOI 10.1161/01.ATV.0000150044.84012.68
-
Levin N, Bischoff ED, Daige CL, et al. Macrophage liver X receptor is required for anti-atherogenic activity of LXR agonists. Arterioscler Thromb Vasc Biol. 2005;25(1):135-142. (Pubitemid 40054266)
-
(2005)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.25
, Issue.1
, pp. 135-142
-
-
Levin, N.1
Bischoff, E.D.2
Daige, C.L.3
Thomas, D.4
Vu, C.T.5
Heyman, R.A.6
Tangirala, R.K.7
Schulman, I.G.8
-
32
-
-
34247330542
-
Nongenomic signaling of the retinoid X receptor through binding and inhibiting Gq in human platelets
-
DOI 10.1182/blood-2006-05-022566
-
Moraes LA, Swales KE, Wray JA, et al. Nongenomic signaling of the retinoid X receptor through binding and inhibiting Gq in human platelets. Blood. 2007;109(9):3741-3744. (Pubitemid 46641723)
-
(2007)
Blood
, vol.109
, Issue.9
, pp. 3741-3744
-
-
Moraes, L.A.1
Swales, K.E.2
Wray, J.A.3
Damazo, A.4
Gibbins, J.M.5
Warner, T.D.6
Bishop-Bailey, D.7
-
33
-
-
4444363344
-
Human bone marrow megakaryocytes and platelets express PPARgamma, and PPARgamma agonists blunt platelet release of CD40 ligand and thromboxanes
-
DOI 10.1182/blood-2004-03-0926
-
Akbiyik F, Ray DM, Gettings KF, et al. Human bone marrow megakaryocytes and platelets express PPARgamma, and PPARgamma agonists blunt platelet release of CD40 ligand and thromboxanes. Blood. 2004;104(5):1361-1368. (Pubitemid 39166512)
-
(2004)
Blood
, vol.104
, Issue.5
, pp. 1361-1368
-
-
Akbiyik, F.1
Ray, D.M.2
Gettings, K.F.3
Blumberg, N.4
Francis, C.W.5
Phipps, R.P.6
-
34
-
-
33644883024
-
Role of nuclear receptor signaling in platelets: Antithrombotic effects of PPARbeta
-
DOI 10.1096/fj.05-4395fje
-
Ali FY, Davidson SJ, Moraes LA, et al. Role of nuclear receptor signaling in platelets: antithrombotic effects of PPARbeta. FASEB J. 2006;20(2):326-328. (Pubitemid 46671159)
-
(2006)
FASEB Journal
, vol.20
, Issue.2
, pp. 326-328
-
-
Ali, F.Y.1
Davidson, S.J.2
Moraes, L.A.3
Traves, S.L.4
Paul-Clark, M.5
Bishop-Bailey, D.6
Warner, T.D.7
Mitchell, J.A.8
-
35
-
-
77949292613
-
Nongenomic effects of PPARgamma ligands: Inhibition of GPVI-stimulated platelet activation
-
Moraes LA, Spyridon M, Kaiser WJ, et al. Nongenomic effects of PPARgamma ligands: inhibition of GPVI-stimulated platelet activation. J Thromb Haemost. 2010;(3)8:577-587.
-
(2010)
J Thromb Haemost
, vol.3
, Issue.8
, pp. 577-587
-
-
Moraes, L.A.1
Spyridon, M.2
Kaiser, W.J.3
-
36
-
-
30444452396
-
Platelet PECAM-1 inhibits thrombus formation in vivo
-
DOI 10.1182/blood-2005-04-1512
-
Patil S, Gross PL, Stapleton M, et al. Platelet PE-CAM-1 inhibits thrombus formation in vivo. Blood. 2006;107(2):535-541. (Pubitemid 43076376)
-
(2006)
Blood
, vol.107
, Issue.2
, pp. 535-541
-
-
Falati, S.1
Patil, S.2
Gross, P.L.3
Stapleton, M.4
Merrill-Skoloff, G.5
Barrett, N.E.6
Pixton, K.L.7
Weiler, H.8
Cooley, B.9
Newman, D.K.10
Newman, P.J.11
Furie, B.C.12
Furie, B.13
Gibbins, J.M.14
-
37
-
-
76649100139
-
Liver X receptor in cholesterol metabolism
-
Zhao C, Dahlman-Wright K. Liver X receptor in cholesterol metabolism. J Endocrinol. 2010;204(3):233-240.
-
(2010)
J Endocrinol
, vol.204
, Issue.3
, pp. 233-240
-
-
Zhao, C.1
Dahlman-Wright, K.2
-
38
-
-
0035895202
-
LXRs control lipid-inducible expression of the apolipoprotein e gene in macrophages and adipocytes
-
DOI 10.1073/pnas.021488798
-
Laffitte BA, Repa JJ, Joseph SB, et al. LXRs control lipid-inducible expression of the apoliprotein E gene in macrophages and adipocytes. Proc Natl Acad Sci U S A. 2001;16(5):507-512. (Pubitemid 32105072)
-
(2001)
Proceedings of the National Academy of Sciences of the United States of America
, vol.98
, Issue.2
, pp. 507-512
-
-
Laffitte, B.A.1
Repa, J.J.2
Joseph, S.B.3
Wilpitz, D.C.4
Kast, H.R.5
Mangelsdorf, D.J.6
Tontonoz, P.7
-
39
-
-
58149388333
-
A dual role for integrin linked kinase in platelets: Regulating integrin function and alpha-granule secretion
-
Tucker KL, Sage T, Stevens JM, et al. A dual role for integrin linked kinase in platelets: regulating integrin function and alpha-granule secretion. Blood. 2008;112(12):4523-4531.
-
(2008)
Blood
, vol.112
, Issue.12
, pp. 4523-4531
-
-
Tucker, K.L.1
Sage, T.2
Stevens, J.M.3
-
40
-
-
14144255498
-
Ligand-binding regulation of LXR/RXR and LXR/PPAR heterodimerizations: SPR technology-based kinetic analysis correlated with molecular dynamics simulation
-
DOI 10.1110/ps.04951405
-
Yue L, Ye F, Gui C, et al. Ligand-binding regulation of LXR/RXR and LXR/PPAR heterodimerizations: SPR technology-based kinetic analysis correlated with molecular dynamics simulation. Protein Sci. 2005;14(3):812-822. (Pubitemid 40283920)
-
(2005)
Protein Science
, vol.14
, Issue.3
, pp. 812-822
-
-
Yue, L.1
Ye, F.2
Gui, C.3
Luo, H.4
Cai, J.5
Shen, J.6
Chen, K.7
Shen, X.8
Jiang, H.9
-
41
-
-
34547652884
-
Ligand activation of LXRbeta reverses atherosclerosis and cellular cholesterol overload in mice lacking LXRalpha and apoE
-
DOI 10.1172/JCI31909
-
Bradley MN, Hong C, Chen M, et al. Ligand activation of LXR beta reverses atherosclerosis and cellular cholesterol overload in mice lacking LXR alpha and apoE. J Clin Invest. 2007;117(8):2337-2346. (Pubitemid 47219578)
-
(2007)
Journal of Clinical Investigation
, vol.117
, Issue.8
, pp. 2337-2346
-
-
Bradley, M.N.1
Hong, C.2
Chen, M.3
Joseph, S.B.4
Wilpitz, D.C.5
Wang, X.6
Lusis, A.J.7
Collins, A.8
Hseuh, W.A.9
Collins, J.L.10
Tangirala, R.K.11
Tontonoz, P.12
-
42
-
-
0037046543
-
Identification of a nonsteroidal liver X receptor agonist through parallel array synthesis of tertiary amines
-
DOI 10.1021/jm0255116
-
Collins JL, Fivush AM, Watson MA, et al. Identification of a non-steroidal liver X receptor agonist through parallel array synthesis of tertiary amines. J Med Chem. 2002;45(10):1963-1966. (Pubitemid 34477709)
-
(2002)
Journal of Medicinal Chemistry
, vol.45
, Issue.10
, pp. 1963-1966
-
-
Collins, J.L.1
Fivush, A.M.2
Watson, M.A.3
Galardi, C.M.4
Lewis, M.C.5
Moore, L.B.6
Parks, D.J.7
Wilson, J.G.8
Tippin, T.K.9
Binz, J.G.10
Plunket, K.D.11
Morgan, D.G.12
Beaudet, E.J.13
Whitney, K.D.14
Kliewer, S.A.15
Willson, T.M.16
-
43
-
-
70349234470
-
The new tyrosine-kinase inhibitor and anticancer drug dasatinib reversely affect platelet activation in vitro and in vivo
-
Gratacap MP, Martin V, Valéra MC, et al. The new tyrosine-kinase inhibitor and anticancer drug dasatinib reversely affect platelet activation in vitro and in vivo. Blood. 2009;114(9):1884-1892.
-
(2009)
Blood
, vol.114
, Issue.9
, pp. 1884-1892
-
-
Gratacap, M.P.1
Martin, V.2
Valéra, M.C.3
-
44
-
-
63049117124
-
Non-classical anti-factor VIII C2 domain antibodies are pathogenic in a murine in vivo bleeding model
-
Meeks SL, Healey JF, Parker ET, Barrow RT, Lollar P. Non-classical anti-factor VIII C2 domain antibodies are pathogenic in a murine in vivo bleeding model. J Thromb Haemost. 2009;7(4):658-664.
-
(2009)
J Thromb Haemost
, vol.7
, Issue.4
, pp. 658-664
-
-
Meeks, S.L.1
Healey, J.F.2
Parker, E.T.3
Barrow, R.T.4
Lollar, P.5
-
45
-
-
70350570592
-
LXR-activating oxysterols induce the expression of inflammatory markers in endothelial cells through LXR-independent mechanisms
-
Morello F, Saglio E, Noghero A, et al. LXR-activating oxysterols induce the expression of inflammatory markers in endothelial cells through LXR-independent mechanisms. Atherosclerosis. 2009;207(1):38-44.
-
(2009)
Atherosclerosis
, vol.207
, Issue.1
, pp. 38-44
-
-
Morello, F.1
Saglio, E.2
Noghero, A.3
-
46
-
-
77953865873
-
High-density lipoproteins, platelets and the pathogenesis of atherosclerosis
-
Nofer J-R, Brodde MF, Kehrel BE. High-density lipoproteins, platelets and the pathogenesis of atherosclerosis. Clin Exp Pharmacol Physiol. 2010;37(7):726-735.
-
(2010)
Clin Exp Pharmacol Physiol
, vol.37
, Issue.7
, pp. 726-735
-
-
Nofer, J.-R.1
Brodde, M.F.2
Kehrel, B.E.3
-
47
-
-
0032472805
-
3 integrin, and GPIbalpha
-
DOI 10.1084/jem.187.3.329
-
Bombeli T, Schwartz BR, Harlan JM. Adhesion of activated platelets to endothelial cells: evidence for GPIIbIIIa-dependent mechanisms and novel roles for endothelial intercellular adhesion molecule 1 (ICAM-1), alphavbeta3 integrin and GPIalpha. J Exp Med. 1998;187(3):329-339. (Pubitemid 28080062)
-
(1998)
Journal of Experimental Medicine
, vol.187
, Issue.3
, pp. 329-339
-
-
Bombeli, T.1
Schwartz, B.R.2
Harlan, J.M.3
-
48
-
-
0028099321
-
Regulation of the protein tyrosine kinase pp72syk by platelet agonists and the integrin alpha IIb beta
-
Clark EA, Shattil SJ, Ginsberg MH, et al. Regulation of the protein tyrosine kinase pp72syk by platelet agonists and the integrin alpha IIb beta. J Biol Chem. 1994;269(46):28859-28864.
-
(1994)
J Biol Chem
, vol.269
, Issue.46
, pp. 28859-28864
-
-
Clark, E.A.1
Shattil, S.J.2
Ginsberg, M.H.3
-
49
-
-
0345687176
-
Src kinase activation by direct interaction with the integrin beta cytoplasmic domain
-
DOI 10.1073/pnas.2336149100
-
Arias-Salgado EG, Lizano S, Sarkar S, et al. Src kinase activation by direct interaction with the integrin beta cytoplasmic domain. Proc Natl Acad Sci U S A. 2003;100(23):13298-13302. (Pubitemid 37444736)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.23
, pp. 13298-13302
-
-
Arias-Salgado, E.G.1
Lizano, S.2
Sarkar, S.3
Brugge, J.S.4
Ginsberg, M.H.5
Shattil, S.J.6
-
50
-
-
0035856483
-
Activation of Syk protein tyrosine kinase through interaction with integrin beta cytoplasmic domains
-
DOI 10.1016/S0960-9822(01)00565-6
-
Woodside DG, Obergfell A, Leng L, et al. Activation of Syk protein tyrosine kinase through interaction with integrin beta cytoplasmic domains. Curr Biol. 2001;11(22):1799-1804. (Pubitemid 33092170)
-
(2001)
Current Biology
, vol.11
, Issue.22
, pp. 1799-1804
-
-
Woodside, D.G.1
Obergfell, A.2
Leng, L.3
Wilsbacher, J.L.4
Miranti, C.K.5
Brugge, J.S.6
Shattil, S.J.7
Ginsberg, M.H.8
-
51
-
-
0141733167
-
3-mediated platelet spreading
-
DOI 10.1074/jbc.M305077200
-
Wonerow P, Pearce AC, Vaux DJ, et al. A critical role for phospholipase Cgamma2 in alpha IIb beta3-mediated platelet spreading. J Biol Chem. 2003;278(39):37520-37529. (Pubitemid 37175273)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.39
, pp. 37520-37529
-
-
Wonerow, P.1
Pearce, A.C.2
Vaux, D.J.3
Watson, S.P.4
-
52
-
-
0035101931
-
Hepatic cholesterol metabolism and resistance to dietary cholesterol in LXRbeta-deficient mice
-
Alberti S, Schuster G, Parini P, et al. Hepatic cholesterol metabolism and resistance to dietary cholesterol in LXRbeta-deficient mice. J Clin Invest. 2001;107(5):565-573. (Pubitemid 32206188)
-
(2001)
Journal of Clinical Investigation
, vol.107
, Issue.5
, pp. 565-573
-
-
Alberti, S.1
Schuster, G.2
Parini, P.3
Feltkamp, D.4
Diczfalusy, U.5
Rudling, M.6
Angelin, B.7
Bjorkhem, I.8
Pettersson, S.9
Gustafsson, J.-A.10
-
53
-
-
33748951579
-
Liver X receptor (LXR)-beta regulation in LXRbeta-deficient mice: Implications for therapeutic targeting
-
DOI 10.1124/mol.106.022608
-
Quinet EM, Savio DA, Halpern AR, et al. Liver X receptor (LXR)-beta regulation in LXRbeta-deficient mice: implications for therapeutic targeting. Mol Pharmacol. 2006;70(4):1340-1349. (Pubitemid 44435986)
-
(2006)
Molecular Pharmacology
, vol.70
, Issue.4
, pp. 1340-1349
-
-
Quinet, E.M.1
Savio, D.A.2
Halpern, A.R.3
Chen, L.4
Schuster, G.U.5
Gustafsson, J.-A.6
Basso, M.D.7
Nambi, P.8
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