메뉴 건너뛰기




Volumn 99, Issue 5, 1997, Pages 838-845

Differential expression of exons 1a and 1c in mRNAs for sterol regulatory element binding protein-1 in human and mouse organs and cultured cells

Author keywords

adipocytes; alternative splicing; cholesterol; fatty acids; liver; SREBP 1

Indexed keywords

DEXAMETHASONE; TRANSCRIPTION FACTOR;

EID: 0030961960     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI119247     Document Type: Article
Times cited : (660)

References (28)
  • 1
    • 0028225462 scopus 로고
    • SREBP-1, a membrane-hound transcription factor released by sterol-regulated proteolysis
    • Wang, X., R. Sato, M.S. Brown, X. Hua, and J.L. Goldstein. 1994. SREBP-1, a membrane-hound transcription factor released by sterol-regulated proteolysis. Cell. 77:53-62.
    • (1994) Cell , vol.77 , pp. 53-62
    • Wang, X.1    Sato, R.2    Brown, M.S.3    Hua, X.4    Goldstein, J.L.5
  • 2
    • 0029797604 scopus 로고    scopus 로고
    • Overproduction of cholesterol and fatty acids causes massive liver enlargement in transgenic mice expressing truncated SREBP-1a
    • Shimano, H., J.D. Horton, R.E. Hammer, I. Shimomura, M.S. Brown, and J.L. Goldstein. 1996. Overproduction of cholesterol and fatty acids causes massive liver enlargement in transgenic mice expressing truncated SREBP-1a. J. Clin. Invest. 98:1575-1584.
    • (1996) J. Clin. Invest. , vol.98 , pp. 1575-1584
    • Shimano, H.1    Horton, J.D.2    Hammer, R.E.3    Shimomura, I.4    Brown, M.S.5    Goldstein, J.L.6
  • 3
    • 0030007427 scopus 로고    scopus 로고
    • ADD1/SREBP1 promotes adipocyte differentiation and gene expression linked to fatty acid metabolism
    • Kim, J.B., and B.M. Spiegelman. 1996. ADD1/SREBP1 promotes adipocyte differentiation and gene expression linked to fatty acid metabolism. Genes Dev. 10:1096-1107.
    • (1996) Genes Dev. , vol.10 , pp. 1096-1107
    • Kim, J.B.1    Spiegelman, B.M.2
  • 4
    • 0028875426 scopus 로고
    • Sterol regulation of fatty acid synthase promoter: Coordinate feedback regulation of two major lipid pathways
    • Bennett, M.K., J.M. Lopez, H.B. Sanchez, and T.F. Osborne. 1995. Sterol regulation of fatty acid synthase promoter: Coordinate feedback regulation of two major lipid pathways. J. Biol. Chem. 270:25578-25583.
    • (1995) J. Biol. Chem. , vol.270 , pp. 25578-25583
    • Bennett, M.K.1    Lopez, J.M.2    Sanchez, H.B.3    Osborne, T.F.4
  • 5
    • 0030070645 scopus 로고    scopus 로고
    • Sterol regulatory element binding protein binds to a cis element in the promoter of the farnesyl diphosphate synthase gene
    • Ericsson, J., S.M. Jackson, B.C. Lee, and P.A. Edwards. 1996. Sterol regulatory element binding protein binds to a cis element in the promoter of the farnesyl diphosphate synthase gene. Proc. Natl. Acad. Sci. USA. 93:945-950.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 945-950
    • Ericsson, J.1    Jackson, S.M.2    Lee, B.C.3    Edwards, P.A.4
  • 6
    • 0028820299 scopus 로고
    • Hairpin orientation of sterol regulatory element binding protein-2 in cell membranes as determined by protease protection
    • Hua, X., J. Sakai, Y.K. Ho, J.L. Goldstein, and M.S. Brown. 1995. Hairpin orientation of sterol regulatory element binding protein-2 in cell membranes as determined by protease protection. J. Biol. Chem. 270:29422-29427.
    • (1995) J. Biol. Chem. , vol.270 , pp. 29422-29427
    • Hua, X.1    Sakai, J.2    Ho, Y.K.3    Goldstein, J.L.4    Brown, M.S.5
  • 7
    • 0029878960 scopus 로고    scopus 로고
    • Regulated cleavage of sterol regulatory element binding proteins (SREBPs) requires sequences on both sides of the endoplasmic reticulum membrane
    • Hua, X., J. Sakai, M.S. Brown, and J.L. Goldstein. 1996. Regulated cleavage of sterol regulatory element binding proteins (SREBPs) requires sequences on both sides of the endoplasmic reticulum membrane. J. Biol. Chem. 271. 10379-10384.
    • (1996) J. Biol. Chem. , vol.271 , pp. 10379-10384
    • Hua, X.1    Sakai, J.2    Brown, M.S.3    Goldstein, J.L.4
  • 8
    • 0030604717 scopus 로고    scopus 로고
    • Sterol-regulated release of SREBP-2 from cell membranes requires two sequential cleavages, one within a transmembrane segment
    • Sakai, J., E.A. Duncan, R.B. Rawson, X. Hua, M.S. Brown, and J.L. Goldstein. 1996. Sterol-regulated release of SREBP-2 from cell membranes requires two sequential cleavages, one within a transmembrane segment. Cell. 85: 1037-1046.
    • (1996) Cell , vol.85 , pp. 1037-1046
    • Sakai, J.1    Duncan, E.A.2    Rawson, R.B.3    Hua, X.4    Brown, M.S.5    Goldstein, J.L.6
  • 9
    • 0027490174 scopus 로고
    • SREBP-1, a basic helix-loop-helix leucine zipper protein that controls transcription of the LDL receptor gene
    • Yokoyama, C., X. Wang, M.R. Briggs, A. Admon, J. Wu, X. Hua, J.L. Goldstein, and M.S. Brown. 1993. SREBP-1, a basic helix-loop-helix leucine zipper protein that controls transcription of the LDL receptor gene. Cell. 75: 187-197.
    • (1993) Cell , vol.75 , pp. 187-197
    • Yokoyama, C.1    Wang, X.2    Briggs, M.R.3    Admon, A.4    Wu, J.5    Hua, X.6    Goldstein, J.L.7    Brown, M.S.8
  • 10
    • 0027139362 scopus 로고
    • SREBP-2, a second basic-helix-loop-helix-leucine zipper protein that stimulates transcription by binding to a sterol regulatory element
    • Hua, X., C. Yokoyama, J. Wu, M.R. Briggs, M.S. Brown, J.L. Goldstein, and X. Wang. 1993. SREBP-2, a second basic-helix-loop-helix-leucine zipper protein that stimulates transcription by binding to a sterol regulatory element. Proc. Natl. Acad. Sci. USA. 90:11603-11607.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 11603-11607
    • Hua, X.1    Yokoyama, C.2    Wu, J.3    Briggs, M.R.4    Brown, M.S.5    Goldstein, J.L.6    Wang, X.7
  • 11
    • 0028360111 scopus 로고
    • Assignment of the membrane attachment, DNA binding, and transcriptional activation domains of sterol regulatory element binding protein-1 (SREBP-1)
    • Sato, R., J. Yang, X. Wang, M.J. Evans, Y.K. Ho, J.L. Goldstein, and M.S. Brown. 1994. Assignment of the membrane attachment, DNA binding, and transcriptional activation domains of sterol regulatory element binding protein-1 (SREBP-1). J. Biol. Chem. 269:17267-17273.
    • (1994) J. Biol. Chem. , vol.269 , pp. 17267-17273
    • Sato, R.1    Yang, J.2    Wang, X.3    Evans, M.J.4    Ho, Y.K.5    Goldstein, J.L.6    Brown, M.S.7
  • 12
    • 0028133279 scopus 로고
    • Sterol-resistant transcription in CHO cells caused by gene rearrangement that truncates SREBP-2
    • Yang, J., R. Sato, J.L. Goldstein, and M.S. Brown. 1994. Sterol-resistant transcription in CHO cells caused by gene rearrangement that truncates SREBP-2. Genes Dev. 8:1910-1919.
    • (1994) Genes Dev. , vol.8 , pp. 1910-1919
    • Yang, J.1    Sato, R.2    Goldstein, J.L.3    Brown, M.S.4
  • 13
    • 0027648820 scopus 로고
    • ADD1: A novel helix-loop-helix transcription factor associated with adipocyte determination and differentiation
    • Tontonoz, P., J.B. Kim, R.A. Graves, and B.M. Spiegelman. 1993. ADD1: a novel helix-loop-helix transcription factor associated with adipocyte determination and differentiation. Mol. Cell. Biol. 13:4753-4759.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 4753-4759
    • Tontonoz, P.1    Kim, J.B.2    Graves, R.A.3    Spiegelman, B.M.4
  • 14
    • 0028839010 scopus 로고
    • Independent regulation of sterol regulatory element binding proteins 1 and 2 in hamster liver
    • Sheng, Z., H. Otani, M.S. Brown, and J.L. Goldstein. 1995. Independent regulation of sterol regulatory element binding proteins 1 and 2 in hamster liver. Proc. Natl. Acad. Sci. USA. 92:935-938.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 935-938
    • Sheng, Z.1    Otani, H.2    Brown, M.S.3    Goldstein, J.L.4
  • 15
    • 0028960739 scopus 로고
    • Structure of human gene encoding sterol regulatory element binding protein-1 (SREBF1) and localization of SREBF1 and SREBF2 to chromosomes 17p11.2 and 22q13
    • Hua, X., J. Wu, J.L. Goldstein, M.S. Brown, and H.H. Hobbs. 1995. Structure of human gene encoding sterol regulatory element binding protein-1 (SREBF1) and localization of SREBF1 and SREBF2 to chromosomes 17p11.2 and 22q13. Genomics. 25:667-673.
    • (1995) Genomics , vol.25 , pp. 667-673
    • Hua, X.1    Wu, J.2    Goldstein, J.L.3    Brown, M.S.4    Hobbs, H.H.5
  • 16
    • 0030907175 scopus 로고    scopus 로고
    • Isoform 1c of sterol regulatory element binding protein is less active than isoform 1a in livers of transgenic mice and in cultured cells
    • 15a. Shimano, H., J.D. Horton, I. Shimomura, R.E. Hammer, M.S. Brown, and J.L. Goldstein. 1997. Isoform 1c of sterol regulatory element binding protein is less active than isoform 1a in livers of transgenic mice and in cultured cells. J. Clin. Invest. 99:846-854.
    • (1997) J. Clin. Invest. , vol.99 , pp. 846-854
    • Shimano, H.1    Horton, J.D.2    Shimomura, I.3    Hammer, R.E.4    Brown, M.S.5    Goldstein, J.L.6
  • 17
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
    • Chomczynski, P., and N. Sacchi. 1987. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162:156-159.
    • (1987) Anal. Biochem. , vol.162 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 18
    • 0026511284 scopus 로고
    • Antisense CCAAT/enhancer-binding protein RNA suppresses coordinate gene expression and triglyceride accumulation during differentiation of 3T3-L1 preadipocytes
    • Lin, F.-T., and M.D. Lane. 1992. Antisense CCAAT/enhancer-binding protein RNA suppresses coordinate gene expression and triglyceride accumulation during differentiation of 3T3-L1 preadipocytes. Genes Dev. 6:533-544.
    • (1992) Genes Dev. , vol.6 , pp. 533-544
    • Lin, F.-T.1    Lane, M.D.2
  • 19
    • 0029887302 scopus 로고    scopus 로고
    • RAP, a specialized chaperone, prevents ligand-induced ER retention and degradation of LDL receptor-related endocytic receptors
    • Willnow, T.E., A. Rohlmann, J. Horton, H. Otani, J.R. Braun, R.E. Hammer, and J. Herz. 1996. RAP, a specialized chaperone, prevents ligand-induced ER retention and degradation of LDL receptor-related endocytic receptors. EMBO (Eur. Mol. Biol. Organ.) J. 15:2632-2639.
    • (1996) EMBO (Eur. Mol. Biol. Organ.) J. , vol.15 , pp. 2632-2639
    • Willnow, T.E.1    Rohlmann, A.2    Horton, J.3    Otani, H.4    Braun, J.R.5    Hammer, R.E.6    Herz, J.7
  • 21
    • 0022970291 scopus 로고
    • Cytoplasmic 3-hydroxy-3-methylglutaryl coenzyme a synthase from the hamster: I. Isolation and sequencing of a full-length cDNA
    • Gil, G., J.L. Goldstein, C.A. Slaughter, and M.S. Brown. 1986. Cytoplasmic 3-hydroxy-3-methylglutaryl coenzyme A synthase from the hamster: I. Isolation and sequencing of a full-length cDNA. J. Biol. Chem. 261:3710-3716.
    • (1986) J. Biol. Chem. , vol.261 , pp. 3710-3716
    • Gil, G.1    Goldstein, J.L.2    Slaughter, C.A.3    Brown, M.S.4
  • 22
    • 0028929262 scopus 로고
    • Role of the low density lipoprotein receptor in the flux of cholesterol through the plasma and across the tissues of the mouse
    • Osono, Y., L.A. Woollett, J. Herz, and J.M. Dietschy. 1995. Role of the low density lipoprotein receptor in the flux of cholesterol through the plasma and across the tissues of the mouse. J. Clin. Invest. 95:1124-1132.
    • (1995) J. Clin. Invest. , vol.95 , pp. 1124-1132
    • Osono, Y.1    Woollett, L.A.2    Herz, J.3    Dietschy, J.M.4
  • 24
    • 0022394722 scopus 로고
    • Human 3-hydroxy-3-methylglutaryl coenzyme a reductase: Conserved domains responsible for catalytic activity and sterol-regulated degradation
    • Luskey, K.L., and B. Stevens. 1985. Human 3-hydroxy-3-methylglutaryl coenzyme A reductase: conserved domains responsible for catalytic activity and sterol-regulated degradation. J. Biol. Chem. 260:10271-10277.
    • (1985) J. Biol. Chem. , vol.260 , pp. 10271-10277
    • Luskey, K.L.1    Stevens, B.2
  • 25
    • 0023664546 scopus 로고
    • The sequence of cDNa encoding lipoprotein lipase: A member of a lipase gene family
    • Kirchgessner, T.G., K.L. Svenson, A.J. Lusis, and M.C . Schotz. 1987. The sequence of cDNA encoding lipoprotein lipase: a member of a lipase gene family. J. Biol. Chem. 262:8463-8466.
    • (1987) J. Biol. Chem. , vol.262 , pp. 8463-8466
    • Kirchgessner, T.G.1    Svenson, K.L.2    Lusis, A.J.3    Schotz, M.C..4
  • 26
    • 0023056546 scopus 로고
    • Nucleotide sequence of a full-length cDNa for mouse cytoskeletal β-actin mRNA
    • Tokunaga, K., H. Taniguchi, K. Yoda, M. Shimizu, and S. Sakiyama. 1986. Nucleotide sequence of a full-length cDNA for mouse cytoskeletal β-actin mRNA. Nucleic Acids Res. 14:2829.
    • (1986) Nucleic Acids Res. , vol.14 , pp. 2829
    • Tokunaga, K.1    Taniguchi, H.2    Yoda, K.3    Shimizu, M.4    Sakiyama, S.5
  • 27
    • 0021759199 scopus 로고
    • Evolutionary conservation in the untranslated regions of actin mRNAs: DNa sequence of a human beta-actin cDNA
    • Ponte, P. S.-Y. Ng, J. Engel, P. Gunning, and L. Kedes. 1984. Evolutionary conservation in the untranslated regions of actin mRNAs: DNA sequence of a human beta-actin cDNA. Nucleic Acids Res. 12:1687-1696.
    • (1984) Nucleic Acids Res. , vol.12 , pp. 1687-1696
    • Ponte, P.1    Ng, S.-Y.2    Engel, J.3    Gunning, P.4    Kedes, L.5
  • 28
    • 0019332750 scopus 로고
    • Human hepatocellular carcinoma cell lines secrete the major plasma proteins and hepatitis B surface antigen
    • Wash. DC
    • Knowles, B.B., C.C. Howe, and D.P. Aden. 1980. Human hepatocellular carcinoma cell lines secrete the major plasma proteins and hepatitis B surface antigen. Science (Wash. DC). 209:497-499.
    • (1980) Science , vol.209 , pp. 497-499
    • Knowles, B.B.1    Howe, C.C.2    Aden, D.P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.