Ubiquitination of 3-hydroxy-3-methylglutaryl-CoA reductase in permeabilized cells mediated by cytosolic E1 and a putative membrane-bound ubiquitin ligase

Journal of Biological Chemistry

Volumn 279, Issue 27, 2004, Pages 28798-28806

  Song, Bao Liang ^a   DeBose Boyd, Russell A ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOLS; BIOSYNTHESIS; CATALYSIS; CHOLESTEROL; ENZYME INHIBITION; ENZYMES;

STEROLS; UBIQUITINATION;

BIOCHEMISTRY;

ADENOSINE TRIPHOSPHATE; CELL PROTEIN; ENZYME; GLYCOPROTEIN E1; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; PROTEIN INSIG 1; PROTEIN INSIG 2; STEROL; UBIQUITIN CONJUGATING ENZYME; UBIQUITIN LIGATING ENZYME; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG;

AMINO ACID SYNTHESIS; ARTICLE; CELL MEMBRANE PERMEABILITY; CONTROLLED STUDY; CYTOSOL; ENDOPLASMIC RETICULUM; ENZYME BINDING; ENZYME DEGRADATION; ENZYME LOCALIZATION; ENZYME MECHANISM; ENZYME MODIFICATION; FEEDBACK SYSTEM; HUMAN; HUMAN CELL; IN VITRO STUDY; MEMBRANE BINDING; PRIORITY JOURNAL; UBIQUITINATION;

ANIMALS; BINDING, COMPETITIVE; CARRIER PROTEINS; CATALYSIS; CELL LINE; CYTOSOL; DIGITONIN; ENDOPLASMIC RETICULUM; FIBROBLASTS; HUMANS; HYDROXYMETHYLGLUTARYL COA REDUCTASES; IMMUNOBLOTTING; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LIGASES; LIVER; MALE; MEMBRANE PROTEINS; MODELS, CHEMICAL; PRECIPITIN TESTS; RATS; RATS, SPRAGUE-DAWLEY; RNA INTERFERENCE; STEROLS; UBIQUITIN; UBIQUITIN-PROTEIN LIGASES;

EID: 3142654791     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M402442200     Document Type: Article

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