Unsaturated fatty acids inhibit transcription of the sterol regulatory element-binding protein-1c (SREBP-1c) gene by antagonizing ligand-dependent activation of the LXR

Proceedings of the National Academy of Sciences of the United States of America

Volumn 98, Issue 11, 2001, Pages 6027-6032

  Ou, Jiafu ^a   Tu, Hua ^a   Shan, Bei ^a   Luk, Alvin ^a   DeBose Boyd, Russell A ^a   Bashmakov, Yuriy ^a   Goldstein, Joseph L ^a   Brown, Michael S ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

Arachidonic acid; Fatty acid synthesis; Nuclear receptors

Indexed keywords

ARACHIDONIC ACID; FATTY ACID; HORMONE RECEPTOR; LIGAND; LIVER X RECEPTOR; MESSENGER RNA; STEROL REGULATORY ELEMENT BINDING PROTEIN; STEROL REGULATORY ELEMENT BINDING PROTEIN 1C; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; UNSATURATED FATTY ACID;

ACID SECRETION; ANIMAL CELL; ARTICLE; BIOSYNTHESIS; CELL CULTURE; CONTROLLED STUDY; FLUORESCENCE POLARIZATION IMMUNOASSAY; HEPATOMA CELL; LIGAND BINDING; NONHUMAN; PRIORITY JOURNAL; RAT; SYNTHESIS; TRANSCRIPTION REGULATION;

ANIMALS; ARACHIDONIC ACID; CCAAT-ENHANCER-BINDING PROTEINS; CELL LINE; CHOLESTEROL; DNA-BINDING PROTEINS; FATTY ACIDS, UNSATURATED; GENE EXPRESSION REGULATION; HELIX-LOOP-HELIX MOTIFS; HUMANS; LEUCINE ZIPPERS; LIGANDS; RATS; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECEPTORS, RETINOIC ACID; RECEPTORS, THYROID HORMONE; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TUMOR CELLS, CULTURED;

ANIMALIA;

EID: 0035932990     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.111138698     Document Type: Article

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