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Volumn 49, Issue 10, 2008, Pages 2079-2088

Mammalian glycerol-3-phosphate acyltransferases: New genes for an old activity

Author keywords

Lipogenesis; Phospholipid synthesis; Triglyceride synthesis

Indexed keywords

ENZYME INHIBITOR; FATTY ACID; GLYCEROL 3 PHOSPHATE ACYLTRANSFERASE; GLYCEROL 3 PHOSPHATE ACYLTRANSFERASE 1; GLYCEROL 3 PHOSPHATE ACYLTRANSFERASE 2; GLYCEROL 3 PHOSPHATE ACYLTRANSFERASE 3; GLYCEROL 3 PHOSPHATE ACYLTRANSFERASE 4; GLYCEROPHOSPHOLIPID; ISOENZYME; N ETHYLMALEIMIDE; REAGENT; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

EID: 66849089864     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.R800013-JLR200     Document Type: Review
Times cited : (102)

References (89)
  • 1
    • 0001031875 scopus 로고
    • Enzymatic esterification of alpha-glycerophosphate by long chain fatty acids
    • Kornberg, A., and W. E. Pricer, Jr. 1953. Enzymatic esterification of alpha-glycerophosphate by long chain fatty acids. J. Biol. Chem. 204: 345-357.
    • (1953) J. Biol. Chem , vol.204 , pp. 345-357
    • Kornberg, A.1    Pricer Jr., W.E.2
  • 2
    • 0345171460 scopus 로고    scopus 로고
    • Enzymes of triacylglycerol synthesis and their regulation
    • Coleman, R. A., and D. P. Lee. 2004. Enzymes of triacylglycerol synthesis and their regulation. Prog. Lipid Res. 43: 134-176.
    • (2004) Prog. Lipid Res , vol.43 , pp. 134-176
    • Coleman, R.A.1    Lee, D.P.2
  • 3
    • 53149087861 scopus 로고    scopus 로고
    • Acyltransferases in bacterial glycerophospholipid synthesis
    • Zhang, Y. M., and C. O. Rock. 2008. Acyltransferases in bacterial glycerophospholipid synthesis. J Lipid Res. 49: 1867-1874.
    • (2008) J Lipid Res , vol.49 , pp. 1867-1874
    • Zhang, Y.M.1    Rock, C.O.2
  • 4
    • 0021112555 scopus 로고
    • The DNA sequences encoding plsB and dgk loci of Escherichia coli
    • Lightner, V.A., R. M. Bell, and P. Modrich. 1983. The DNA sequences encoding plsB and dgk loci of Escherichia coli. J. Biol. Chem. 258: 10856-10861.
    • (1983) J. Biol. Chem , vol.258 , pp. 10856-10861
    • Lightner, V.A.1    Bell, R.M.2    Modrich, P.3
  • 5
    • 0019200914 scopus 로고
    • Membrane phospholipid synthesis in Escherichia coli. Cloning of a structural gene (plsB) of the sn-glycerol-3-phosphate acyl/transferase
    • Lightner, V. A., T. J. Larson, P. Tailleur, G. D. Kantor, C. R. Raetz, R. M. Bell, and P. Modrich. 1980. Membrane phospholipid synthesis in Escherichia coli. Cloning of a structural gene (plsB) of the sn-glycerol-3-phosphate acyl/transferase. J. Biol. Chem. 255: 9413-9420.
    • (1980) J. Biol. Chem , vol.255 , pp. 9413-9420
    • Lightner, V.A.1    Larson, T.J.2    Tailleur, P.3    Kantor, G.D.4    Raetz, C.R.5    Bell, R.M.6    Modrich, P.7
  • 7
    • 0033522379 scopus 로고    scopus 로고
    • Analysis of amino acid motifs diagnostic for the sn-glycerol-3-phosphate acyl-transferase reaction
    • Lewin, T. M., P. Wang, and R. A. Coleman. 1999. Analysis of amino acid motifs diagnostic for the sn-glycerol-3-phosphate acyl-transferase reaction. Biochemistry. 38: 5764-5771.
    • (1999) Biochemistry , vol.38 , pp. 5764-5771
    • Lewin, T.M.1    Wang, P.2    Coleman, R.A.3
  • 8
    • 0031553029 scopus 로고    scopus 로고
    • sn-Glycerol-3-phosphate acyltransferase from Escherichia coli
    • Wilkison, W. O., and R. M. Bell. 1997. sn-Glycerol-3-phosphate acyltransferase from Escherichia coli. Biochim. Biophys. Acta. 1348: 3-9.
    • (1997) Biochim. Biophys. Acta , vol.1348 , pp. 3-9
    • Wilkison, W.O.1    Bell, R.M.2
  • 9
    • 0018846846 scopus 로고
    • Enzymes of glycerolipid synthesis in eukaryotes
    • Bell, R. M., and R. A. Coleman. 1980. Enzymes of glycerolipid synthesis in eukaryotes. Annu. Rev. Biochem. 49: 459-487.
    • (1980) Annu. Rev. Biochem , vol.49 , pp. 459-487
    • Bell, R.M.1    Coleman, R.A.2
  • 10
    • 0029551631 scopus 로고
    • Glycerolipid biosynthesis in peroxisomes (microbodies)
    • Hajra, A. K. 1995. Glycerolipid biosynthesis in peroxisomes (microbodies). Prog. Lipid Res. 34: 343-364.
    • (1995) Prog. Lipid Res , vol.34 , pp. 343-364
    • Hajra, A.K.1
  • 11
    • 0042131525 scopus 로고    scopus 로고
    • Inactivation of ether lipid biosynthesis causes male infertility, defects in eye development and optic nerve hypoplasia in mice
    • Rodemer, C., T. P. Thai, B. Brugger, T. Kaercher, H. Werner, K. A. Nave, F. Wieland, K. Gorgas, and W. W. Just. 2003. Inactivation of ether lipid biosynthesis causes male infertility, defects in eye development and optic nerve hypoplasia in mice. Hum. Mol. Genet. 12: 1881-1895.
    • (2003) Hum. Mol. Genet , vol.12 , pp. 1881-1895
    • Rodemer, C.1    Thai, T.P.2    Brugger, B.3    Kaercher, T.4    Werner, H.5    Nave, K.A.6    Wieland, F.7    Gorgas, K.8    Just, W.W.9
  • 12
    • 33845339567 scopus 로고    scopus 로고
    • The ether lipid-deficient mouse: Tracking down plasmalogen functions
    • Gorgas, K., A. Teigler, D. Komljenovic, and W. W. Just. 2006. The ether lipid-deficient mouse: tracking down plasmalogen functions. Biochim. Biophys. Acta. 1763: 1511-1526.
    • (2006) Biochim. Biophys. Acta , vol.1763 , pp. 1511-1526
    • Gorgas, K.1    Teigler, A.2    Komljenovic, D.3    Just, W.W.4
  • 13
    • 21744435277 scopus 로고    scopus 로고
    • Role of dihydroxyacetonephosphate acyltransferase in the biosynthesis of plasmalogens and nonether glycerolipids
    • Liu, D., N. Nagan, W. W. Just, C. Rodemer, T-P. Thai, and R. A. Zoeller. 2005. Role of dihydroxyacetonephosphate acyltransferase in the biosynthesis of plasmalogens and nonether glycerolipids. J. Lipid Res. 46: 727-735.
    • (2005) J. Lipid Res , vol.46 , pp. 727-735
    • Liu, D.1    Nagan, N.2    Just, W.W.3    Rodemer, C.4    Thai, T.-P.5    Zoeller, R.A.6
  • 14
    • 0031897918 scopus 로고    scopus 로고
    • Acyl-CoA:dihydroxyacetonephosphate acyltransferase: Cloning of the human cDNA and resolution of the molecular basis in rhizomelic chondrodysplasia punctata type 2
    • Ofman, R., E. H. Hettema, E. M. Hogenhout, U. Caruso, A. O. Muijsers, and R. J. Wanders. 1998. Acyl-CoA:dihydroxyacetonephosphate acyltransferase: cloning of the human cDNA and resolution of the molecular basis in rhizomelic chondrodysplasia punctata type 2. Hum. Mol. Genet. 7: 847-853.
    • (1998) Hum. Mol. Genet , vol.7 , pp. 847-853
    • Ofman, R.1    Hettema, E.H.2    Hogenhout, E.M.3    Caruso, U.4    Muijsers, A.O.5    Wanders, R.J.6
  • 16
    • 0034737640 scopus 로고    scopus 로고
    • Induction of the peroxisomal glycerolipid-synthesizing enzymes during differentiation of 3T3-L1 adipocytes. Role in triacylglycerol synthesis
    • Hajra, A. K., L. K. Larkins, A. K. Das, N. Hemati, R. L. Erickson, and O. A. MacDougald. 2000. Induction of the peroxisomal glycerolipid-synthesizing enzymes during differentiation of 3T3-L1 adipocytes. Role in triacylglycerol synthesis. J. Biol. Chem. 275: 9441-9446.
    • (2000) J. Biol. Chem , vol.275 , pp. 9441-9446
    • Hajra, A.K.1    Larkins, L.K.2    Das, A.K.3    Hemati, N.4    Erickson, R.L.5    MacDougald, O.A.6
  • 17
    • 0030175841 scopus 로고    scopus 로고
    • Biosynthesis of triacylglycerols
    • Lehner, R., and A. Kuksis. 1996. Biosynthesis of triacylglycerols. Prog. Lipid Res. 35: 169-201.
    • (1996) Prog. Lipid Res , vol.35 , pp. 169-201
    • Lehner, R.1    Kuksis, A.2
  • 18
    • 0038607416 scopus 로고    scopus 로고
    • Congenital generalized lipodystrophy: Significance of triglyceride biosynthetic pathways
    • Agarwal, A. K., and A. Garg. 2003. Congenital generalized lipodystrophy: significance of triglyceride biosynthetic pathways. Trends Endocrinol. Metab. 14: 214-221.
    • (2003) Trends Endocrinol. Metab , vol.14 , pp. 214-221
    • Agarwal, A.K.1    Garg, A.2
  • 19
    • 37449000957 scopus 로고    scopus 로고
    • The lipin protein family: Dual roles in lipid biosynthesis and gene expression
    • Reue, K., and P. Zhang. 2008. The lipin protein family: dual roles in lipid biosynthesis and gene expression. FEBS Lett. 582: 90-96.
    • (2008) FEBS Lett , vol.582 , pp. 90-96
    • Reue, K.1    Zhang, P.2
  • 20
    • 36849000320 scopus 로고    scopus 로고
    • Genetic factors in type 2 diabetes: All in the (lipin) family
    • Reue, K., and J. Donkor. 2007. Genetic factors in type 2 diabetes: all in the (lipin) family. Diabetes. 56: 2842-2843.
    • (2007) Diabetes , vol.56 , pp. 2842-2843
    • Reue, K.1    Donkor, J.2
  • 21
    • 22244469461 scopus 로고    scopus 로고
    • Homozygous mutations in LPIN2 are responsible for the syndrome of chronic recurrent multifocal osteomyelitis and congenital dyserythropoietic anaemia (Majeed syndrome)
    • Ferguson, P. J., S. Chen, M. K. Tayeh, L. Ochoa, S. M. Leal, A. Pelet, A. Munnich, S. Lyonnet, H. A. Majeed, and H. El-Shanti. 2005. Homozygous mutations in LPIN2 are responsible for the syndrome of chronic recurrent multifocal osteomyelitis and congenital dyserythropoietic anaemia (Majeed syndrome). J. Med. Genet. 42: 551-557.
    • (2005) J. Med. Genet , vol.42 , pp. 551-557
    • Ferguson, P.J.1    Chen, S.2    Tayeh, M.K.3    Ochoa, L.4    Leal, S.M.5    Pelet, A.6    Munnich, A.7    Lyonnet, S.8    Majeed, H.A.9    El-Shanti, H.10
  • 22
    • 0010044876 scopus 로고    scopus 로고
    • The structure and functions of human lysophosphatidic acid acyltransferases
    • Leung, D. W. 2001. The structure and functions of human lysophosphatidic acid acyltransferases. Front. Biosci. 6: D944-D953.
    • (2001) Front. Biosci , vol.6
    • Leung, D.W.1
  • 23
    • 33749595083 scopus 로고    scopus 로고
    • Lysophosphatidic acid acyltransferase-beta (LPAAT-beta) is highly expressed in advanced ovarian cancer and is associated with aggressive histology and poor survival
    • Diefenbach, C. S., R. A. Soslow, A. Iasonos, I. Linkov, C. Hedvat, L. Bonham, J. Singer, R. R. Barakat, C. Aghajanian, and J. Dupont. 2006. Lysophosphatidic acid acyltransferase-beta (LPAAT-beta) is highly expressed in advanced ovarian cancer and is associated with aggressive histology and poor survival. Cancer. 107: 1511-1519.
    • (2006) Cancer , vol.107 , pp. 1511-1519
    • Diefenbach, C.S.1    Soslow, R.A.2    Iasonos, A.3    Linkov, I.4    Hedvat, C.5    Bonham, L.6    Singer, J.7    Barakat, R.R.8    Aghajanian, C.9    Dupont, J.10
  • 24
    • 33751302125 scopus 로고    scopus 로고
    • Antileukemic activity of lysophosphatidic acid acyltransferase-beta inhibitor CT32228 in chronic myelogenous leukemia sensitive and resistant to imatinib
    • La Rosee, P., T. Jia, S. Demehri, N. Hartel, P. de Vries, L. Bonham, D. Hollenback, J. W. Singer, J. V. Melo, B. J. Druker, et al. 2006. Antileukemic activity of lysophosphatidic acid acyltransferase-beta inhibitor CT32228 in chronic myelogenous leukemia sensitive and resistant to imatinib. Clin. Cancer Res. 12: 6540-6546.
    • (2006) Clin. Cancer Res , vol.12 , pp. 6540-6546
    • La Rosee, P.1    Jia, T.2    Demehri, S.3    Hartel, N.4    de Vries, P.5    Bonham, L.6    Hollenback, D.7    Singer, J.W.8    Melo, J.V.9    Druker, B.J.10
  • 25
    • 14744304497 scopus 로고    scopus 로고
    • Inhibition of triglyceride synthesis as a treatment strategy for obesity: Lessons from DGAT1-deficient mice
    • Chen, H. C., and R. V. Farese, Jr. 2005. Inhibition of triglyceride synthesis as a treatment strategy for obesity: lessons from DGAT1-deficient mice. Arterioscler. Thromb. Vasc. Biol. 25: 482-486.
    • (2005) Arterioscler. Thromb. Vasc. Biol , vol.25 , pp. 482-486
    • Chen, H.C.1    Farese Jr., R.V.2
  • 26
    • 39149122218 scopus 로고    scopus 로고
    • Validation of diacyl glycerolacyltransferase I as a novel target for the treatment of obesity and dyslipidemia using a potent and selective small molecule inhibitor
    • Zhao, G., A. J. Souers, M. Voorbach, H. D. Falls, B. Droz, S. Brodjian, Y. Y. Lau, R. R. Iyengar, J. Gao, A. S. Judd, et al. 2008. Validation of diacyl glycerolacyltransferase I as a novel target for the treatment of obesity and dyslipidemia using a potent and selective small molecule inhibitor. J. Med. Chem. 51: 380-383.
    • (2008) J. Med. Chem , vol.51 , pp. 380-383
    • Zhao, G.1    Souers, A.J.2    Voorbach, M.3    Falls, H.D.4    Droz, B.5    Brodjian, S.6    Lau, Y.Y.7    Iyengar, R.R.8    Gao, J.9    Judd, A.S.10
  • 27
    • 0018348041 scopus 로고
    • Evidence for the existence of isoenzymes of glycerol phosphate acyltransferase
    • Nimmo, H. G. 1979. Evidence for the existence of isoenzymes of glycerol phosphate acyltransferase. Biochem. J. 177: 283-288.
    • (1979) Biochem. J , vol.177 , pp. 283-288
    • Nimmo, H.G.1
  • 28
    • 0018710854 scopus 로고
    • A study of the glycerol phosphate acyltransferase and dihydroxyacetone phosphate acyltransferase activities in rat liver mitochondrial and microsomal fractions. Relative distribution in parenchymal and non-parenchymal cells, effects of N-ethylmaleimide, palmitoyl-coenzyme A concentration, starvation, adrenalectomy and anti-insulin serum treatment
    • Bates, E. J., and E. D. Saggerson. 1979. A study of the glycerol phosphate acyltransferase and dihydroxyacetone phosphate acyltransferase activities in rat liver mitochondrial and microsomal fractions. Relative distribution in parenchymal and non-parenchymal cells, effects of N-ethylmaleimide, palmitoyl-coenzyme A concentration, starvation, adrenalectomy and anti-insulin serum treatment. Biochem. J. 182: 751-762.
    • (1979) Biochem. J , vol.182 , pp. 751-762
    • Bates, E.J.1    Saggerson, E.D.2
  • 29
    • 0019325607 scopus 로고
    • Subcellular distribution and some properties of N-ethylmaleimide-sensitive and-insensitive forms of glycerol phosphate acyltransferase in rat adipocytes
    • Saggerson, E. D., C. A. Carpenter, C. H. Cheng, and S. R. Sooranna. 1980. Subcellular distribution and some properties of N-ethylmaleimide-sensitive and-insensitive forms of glycerol phosphate acyltransferase in rat adipocytes. Biochem. J. 190: 183-189.
    • (1980) Biochem. J , vol.190 , pp. 183-189
    • Saggerson, E.D.1    Carpenter, C.A.2    Cheng, C.H.3    Sooranna, S.R.4
  • 30
    • 0023830029 scopus 로고
    • Comparison of triacylglycerol synthesis in rat brown and white adipocytes. Effects of hypothyroidism and streptozotocin-diabetes on enzyme activities and metabolic fluxes
    • Baht, H. S., and E. D. Saggerson. 1988. Comparison of triacylglycerol synthesis in rat brown and white adipocytes. Effects of hypothyroidism and streptozotocin-diabetes on enzyme activities and metabolic fluxes. Biochem. J. 250: 325-333.
    • (1988) Biochem. J , vol.250 , pp. 325-333
    • Baht, H.S.1    Saggerson, E.D.2
  • 31
    • 0027383706 scopus 로고
    • Expression and identification of p90 as the murine mitochondrial glycerol- 3-phosphate acyltransferase
    • Yet, S. F., S. Lee, H. Young Tae, and S. Hei Sook. 1993. Expression and identification of p90 as the murine mitochondrial glycerol- 3-phosphate acyltransferase. Biochemistry. 32: 9486-9491.
    • (1993) Biochemistry , vol.32 , pp. 9486-9491
    • Yet, S.F.1    Lee, S.2    Young Tae, H.3    Hei Sook, S.4
  • 32
    • 0018070657 scopus 로고
    • Selective changes in microsomal enzymes of triacylglycerol phosphatidylcholine, and phosphatidylethanolamine biosynthesis during differentiation of 3T3-L1 preadipocytes
    • Coleman, R. A., B. C. Reed, J. C. Mackall, A. K. Student, M. D. Lane, and R. M. Bell. 1978. Selective changes in microsomal enzymes of triacylglycerol phosphatidylcholine, and phosphatidylethanolamine biosynthesis during differentiation of 3T3-L1 preadipocytes. J. Biol. Chem. 253: 7256-7261.
    • (1978) J. Biol. Chem , vol.253 , pp. 7256-7261
    • Coleman, R.A.1    Reed, B.C.2    Mackall, J.C.3    Student, A.K.4    Lane, M.D.5    Bell, R.M.6
  • 33
    • 0031576031 scopus 로고    scopus 로고
    • Glycerolipid metabolizing enzymes in rat ventricle and in cardiac myocytes
    • Swanton, E. M., and E. D. Saggerson. 1997. Glycerolipid metabolizing enzymes in rat ventricle and in cardiac myocytes. Biochim. Biophys. Acta. 1346: 93-102.
    • (1997) Biochim. Biophys. Acta , vol.1346 , pp. 93-102
    • Swanton, E.M.1    Saggerson, E.D.2
  • 34
    • 50949096938 scopus 로고    scopus 로고
    • Mice deficient in mitochondrial glycerol-3-phosphate acyltransferase-1 have diminished myocardial triacylglycerol accumulation during lipogenic diet and altered phospholipid fatty acid composition
    • Lewin, T. M., H. de Jong, N. J. Schwerbrock, L. E. Hammond, S. M. Watkins, T. P. Combs, and R. A. Coleman. 2008. Mice deficient in mitochondrial glycerol-3-phosphate acyltransferase-1 have diminished myocardial triacylglycerol accumulation during lipogenic diet and altered phospholipid fatty acid composition. Biochim Biophys Acta. 1781: 352-358.
    • (2008) Biochim Biophys Acta , vol.1781 , pp. 352-358
    • Lewin, T.M.1    de Jong, H.2    Schwerbrock, N.J.3    Hammond, L.E.4    Watkins, S.M.5    Combs, T.P.6    Coleman, R.A.7
  • 35
    • 0019908040 scopus 로고
    • Acyl-CoA: Sn-glycerol-3-phosphate O-acyltransferase in rat brain mitochondria and microsomes
    • Fitzpatrick, S. M., G. Sorresso, and D. Haldar. 1982. Acyl-CoA: sn-glycerol-3-phosphate O-acyltransferase in rat brain mitochondria and microsomes. J. Neurochem. 39: 286-289.
    • (1982) J. Neurochem , vol.39 , pp. 286-289
    • Fitzpatrick, S.M.1    Sorresso, G.2    Haldar, D.3
  • 36
    • 0037031840 scopus 로고    scopus 로고
    • Coordinate regulation of malonyl-CoA decarboxylase, sn-glycerol-3-phosphate acyltransferase, and acetyl-CoA carboxylase by AMP-activated protein kinase in rat tissues in response to exercise
    • Park, H., V. K. Kaushik, S. Constant, M. Prentki, E. Przybytkowski, N. B. Ruderman, and A. K. Saha. 2002. Coordinate regulation of malonyl-CoA decarboxylase, sn-glycerol-3-phosphate acyltransferase, and acetyl-CoA carboxylase by AMP-activated protein kinase in rat tissues in response to exercise. J. Biol. Chem. 277: 32571-32577.
    • (2002) J. Biol. Chem , vol.277 , pp. 32571-32577
    • Park, H.1    Kaushik, V.K.2    Constant, S.3    Prentki, M.4    Przybytkowski, E.5    Ruderman, N.B.6    Saha, A.K.7
  • 37
    • 0031048115 scopus 로고    scopus 로고
    • Increased lipogenic capacity of the islets of obese rats: A role in the pathogenesis of NIDDM
    • Lee, Y., H. Hirose, Y. T. Zhou, V. Esser, J. D. McGarry, and R. H. Unger. 1997. Increased lipogenic capacity of the islets of obese rats: a role in the pathogenesis of NIDDM. Diabetes. 46: 408-413.
    • (1997) Diabetes , vol.46 , pp. 408-413
    • Lee, Y.1    Hirose, H.2    Zhou, Y.T.3    Esser, V.4    McGarry, J.D.5    Unger, R.H.6
  • 38
    • 0019818422 scopus 로고
    • The activities of lipoprotein lipase and of enzymes involved in triacylglycerol synthesis in rat adipose tissue. Effects of starvation, dietary modification and of corticotropin injection
    • Lawson, N., A. D. Pollard, R. J. Jennings, M. I. Gurr, and D. N. Brindley. 1981. The activities of lipoprotein lipase and of enzymes involved in triacylglycerol synthesis in rat adipose tissue. Effects of starvation, dietary modification and of corticotropin injection. Biochem. J. 200: 285-294.
    • (1981) Biochem. J , vol.200 , pp. 285-294
    • Lawson, N.1    Pollard, A.D.2    Jennings, R.J.3    Gurr, M.I.4    Brindley, D.N.5
  • 39
    • 0033559856 scopus 로고    scopus 로고
    • AMP-activated kinase reciprocally regulates triacylglycerol synthesis and fatty acid oxidation in liver and muscle: Evidence that sn-glycerol- 3-phosphate acyltransferase is a novel target
    • Muoio, D. M., K. Seefeld, L. A. Witters, and R. A. Coleman. 1999. AMP-activated kinase reciprocally regulates triacylglycerol synthesis and fatty acid oxidation in liver and muscle: evidence that sn-glycerol- 3-phosphate acyltransferase is a novel target. Biochem. J. 338: 783-791.
    • (1999) Biochem. J , vol.338 , pp. 783-791
    • Muoio, D.M.1    Seefeld, K.2    Witters, L.A.3    Coleman, R.A.4
  • 40
    • 3042569137 scopus 로고    scopus 로고
    • Overexpression of mitochondrial GPAT in rat hepatocytes leads to decreased fatty acid oxidation and increased glycerolipid biosynthesis
    • Linden, D., L. William-Olsson, M. Rhedin, A. K. Asztely, J. C. Clapham, and S. Schreyer. 2004. Overexpression of mitochondrial GPAT in rat hepatocytes leads to decreased fatty acid oxidation and increased glycerolipid biosynthesis. J. Lipid Res. 45: 1279-1288.
    • (2004) J. Lipid Res , vol.45 , pp. 1279-1288
    • Linden, D.1    William-Olsson, L.2    Rhedin, M.3    Asztely, A.K.4    Clapham, J.C.5    Schreyer, S.6
  • 41
    • 0023693069 scopus 로고
    • Changes in activities of some enzymes of glycerolipid synthesis in brown adipose tissue of cold-acclimated rats
    • Darnley, A. C., C. A. Carpenter, and E. D. Saggerson. 1988. Changes in activities of some enzymes of glycerolipid synthesis in brown adipose tissue of cold-acclimated rats. Biochem. J. 253: 351-355.
    • (1988) Biochem. J , vol.253 , pp. 351-355
    • Darnley, A.C.1    Carpenter, C.A.2    Saggerson, E.D.3
  • 42
    • 0025743505 scopus 로고
    • Activities of enzymes of glycerolipid synthesis in brown adipose tissue after treatment of rats with the adrenergic agonists BRL 26830A and phenylephrine, after exposure to cold and in streptozotocin-diabetes
    • Mitchell, J. R. D., and E. D. Saggerson. 1991. Activities of enzymes of glycerolipid synthesis in brown adipose tissue after treatment of rats with the adrenergic agonists BRL 26830A and phenylephrine, after exposure to cold and in streptozotocin-diabetes. Biochem. J. 277: 665-669.
    • (1991) Biochem. J , vol.277 , pp. 665-669
    • Mitchell, J.R.D.1    Saggerson, E.D.2
  • 43
    • 0028176350 scopus 로고
    • The response of brown adipose tissue mitochondrial glycerolphosphate acyltransferase to cold-exposure in hypothyroidism, after adrenalectomy and after treatment with cycloheximide
    • Mitchell, J. R. D., and E. D. Saggerson. 1994. The response of brown adipose tissue mitochondrial glycerolphosphate acyltransferase to cold-exposure in hypothyroidism, after adrenalectomy and after treatment with cycloheximide. Int. J. Biochem. 26: 67-72.
    • (1994) Int. J. Biochem , vol.26 , pp. 67-72
    • Mitchell, J.R.D.1    Saggerson, E.D.2
  • 45
    • 0023926825 scopus 로고
    • Cloning and expression of mouse fatty acid synthase and other specific mRNAs. Developmental and hormonal regulation in 3T3-L1 cells
    • Paulauskis, J. D., and H. S. Sul. 1988. Cloning and expression of mouse fatty acid synthase and other specific mRNAs. Developmental and hormonal regulation in 3T3-L1 cells. J. Biol. Chem. 263: 7049-7054.
    • (1988) J. Biol. Chem , vol.263 , pp. 7049-7054
    • Paulauskis, J.D.1    Sul, H.S.2
  • 46
    • 0026352592 scopus 로고
    • Transcriptional regulation of p90 with sequence homology to Escherichia coli glycerol-3-phosphate acyltransferase
    • Shin, D. H., J. D. Paulauskis, N. Moustaid, and H. S. Sul. 1991. Transcriptional regulation of p90 with sequence homology to Escherichia coli glycerol-3-phosphate acyltransferase. J. Biol. Chem. 266: 23834-23839.
    • (1991) J. Biol. Chem , vol.266 , pp. 23834-23839
    • Shin, D.H.1    Paulauskis, J.D.2    Moustaid, N.3    Sul, H.S.4
  • 47
    • 0029079129 scopus 로고
    • Purification and reconstitution of murine mitochondrial glycerol-3- phosphate acyltransferase. Functional expression in baculovirus-infected insect cells
    • Yet, S. F., M. Yangha Kim, and S. Hei Sook. 1995. Purification and reconstitution of murine mitochondrial glycerol-3- phosphate acyltransferase. Functional expression in baculovirus-infected insect cells. Biochemistry. 34: 7303-7310.
    • (1995) Biochemistry , vol.34 , pp. 7303-7310
    • Yet, S.F.1    Yangha Kim, M.2    Hei Sook, S.3
  • 48
    • 0036889152 scopus 로고    scopus 로고
    • Mitochondrial glycerol-3-phosphate acyltransferase-deficient mice have reduced weight and liver triacylglycerol content and altered glycerolipid fatty acid composition
    • Hammond, L. E., P. A. Gallagher, S. Wang, S. Hiller, K. D. Kluckman, E. L. Posey-Marcos, N. Maeda, and R. A. Coleman. 2002. Mitochondrial glycerol-3-phosphate acyltransferase-deficient mice have reduced weight and liver triacylglycerol content and altered glycerolipid fatty acid composition. Mol. Cell. Biol. 22: 8204-8214.
    • (2002) Mol. Cell. Biol , vol.22 , pp. 8204-8214
    • Hammond, L.E.1    Gallagher, P.A.2    Wang, S.3    Hiller, S.4    Kluckman, K.D.5    Posey-Marcos, E.L.6    Maeda, N.7    Coleman, R.A.8
  • 49
    • 1842741311 scopus 로고    scopus 로고
    • Identification of a new glycerol-3- phosphate acyltransferase isoenzyme, mtGPAT2, in mitochondria
    • Lewin, T. M., N. M. J. Schwerbrock, D. P. Lee, and R. A. Coleman. 2004. Identification of a new glycerol-3- phosphate acyltransferase isoenzyme, mtGPAT2, in mitochondria. J. Biol. Chem. 279: 13488-13495.
    • (2004) J. Biol. Chem , vol.279 , pp. 13488-13495
    • Lewin, T.M.1    Schwerbrock, N.M.J.2    Lee, D.P.3    Coleman, R.A.4
  • 50
    • 0032771711 scopus 로고    scopus 로고
    • Rat sn-glycerol-3-phosphate acyltransferase: Molecular cloning and characterization of the cDNA and expressed protein
    • Ganesh Bhat, B., P. Wang, J. H. Kim, T. M. Black, T. M. Lewin, F. T. Fiedorek, Jr., and R. A. Coleman. 1999. Rat sn-glycerol-3-phosphate acyltransferase: molecular cloning and characterization of the cDNA and expressed protein. Biochim. Biophys. Acta. 1439: 415-423.
    • (1999) Biochim. Biophys. Acta , vol.1439 , pp. 415-423
    • Ganesh Bhat, B.1    Wang, P.2    Kim, J.H.3    Black, T.M.4    Lewin, T.M.5    Fiedorek Jr., F.T.6    Coleman, R.A.7
  • 51
    • 0028104966 scopus 로고
    • Purification and characterization of glycerophosphate acyltransferase from rat liver mitochondria
    • Vancura, A., and D. Haldar. 1994. Purification and characterization of glycerophosphate acyltransferase from rat liver mitochondria. J. Biol. Chem. 269: 27209-27215.
    • (1994) J. Biol. Chem , vol.269 , pp. 27209-27215
    • Vancura, A.1    Haldar, D.2
  • 52
    • 0035580555 scopus 로고    scopus 로고
    • Regulation of mitochondrial sn-glycerol-3-phosphate acyltransferase activity: Response to feeding status is unique in various rat tissues and is discordant with protein expression
    • Lewin, T. M., D. A. Granger, J. H. Kim, and R. A. Coleman. 2001. Regulation of mitochondrial sn-glycerol-3-phosphate acyltransferase activity: response to feeding status is unique in various rat tissues and is discordant with protein expression. Arch. Biochem. Biophys. 396: 119-127.
    • (2001) Arch. Biochem. Biophys , vol.396 , pp. 119-127
    • Lewin, T.M.1    Granger, D.A.2    Kim, J.H.3    Coleman, R.A.4
  • 53
    • 33845941190 scopus 로고    scopus 로고
    • Molecular identification of microsomal acyl-CoA:glycerol-3-phosphate acyltransferase, a key enzyme in de novo triacylglycerol synthesis
    • Cao, J., J. L. Li, D. Li, J. F. Tobin, and R. E. Gimeno. 2006. Molecular identification of microsomal acyl-CoA:glycerol-3-phosphate acyltransferase, a key enzyme in de novo triacylglycerol synthesis. Proc. Natl. Acad. Sci. USA. 103: 19695-19700.
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 19695-19700
    • Cao, J.1    Li, J.L.2    Li, D.3    Tobin, J.F.4    Gimeno, R.E.5
  • 54
    • 0028804539 scopus 로고
    • Characterization of the murine mitochondrial glycerol-3-phosphate acyltransferase promoter
    • Jerkins, A. A., W. R. Liu, S. Lee, and H. S. Sul. 1995. Characterization of the murine mitochondrial glycerol-3-phosphate acyltransferase promoter. J. Biol. Chem. 270: 1416-1421.
    • (1995) J. Biol. Chem , vol.270 , pp. 1416-1421
    • Jerkins, A.A.1    Liu, W.R.2    Lee, S.3    Sul, H.S.4
  • 55
    • 0030904931 scopus 로고    scopus 로고
    • Identification of glycerol-3-phosphate acyltransferase as an adipocyte determination and differentiation factor 1- and sterol regulatory element-binding protein-responsive gene
    • Ericsson, J., S. M. Jackson, J. B. Kim, B. M. Spiegelman, and P. A. Edwards. 1997. Identification of glycerol-3-phosphate acyltransferase as an adipocyte determination and differentiation factor 1- and sterol regulatory element-binding protein-responsive gene. J. Biol. Chem. 272: 7298-7305.
    • (1997) J. Biol. Chem , vol.272 , pp. 7298-7305
    • Ericsson, J.1    Jackson, S.M.2    Kim, J.B.3    Spiegelman, B.M.4    Edwards, P.A.5
  • 56
    • 38349076584 scopus 로고    scopus 로고
    • The presence of distal and proximal promoters for rat mitochondrial glycerol-3-phosphate acyltransferase
    • Aneja, K. K., P. Guha, R. Y. Shilpi, S. Chakraborty, L. M. Schramm, and D. Haldar. 2008. The presence of distal and proximal promoters for rat mitochondrial glycerol-3-phosphate acyltransferase. Arch. Biochem. Biophys. 470: 35-43.
    • (2008) Arch. Biochem. Biophys , vol.470 , pp. 35-43
    • Aneja, K.K.1    Guha, P.2    Shilpi, R.Y.3    Chakraborty, S.4    Schramm, L.M.5    Haldar, D.6
  • 57
    • 0036392132 scopus 로고    scopus 로고
    • Casein kinase II stimulates rat liver mitochondrial glycerophosphate acyltransferase activity
    • Onorato, T. M., and D. Haldar. 2002. Casein kinase II stimulates rat liver mitochondrial glycerophosphate acyltransferase activity. Biochem. Biophys. Res. Commun. 296: 1091-1096.
    • (2002) Biochem. Biophys. Res. Commun , vol.296 , pp. 1091-1096
    • Onorato, T.M.1    Haldar, D.2
  • 58
    • 21244453926 scopus 로고    scopus 로고
    • Phosphorylation of rat liver mitochondrial glycerol-3-phosphate acyltransferase by casein kinase 2
    • Onorato, T. M., S. Chakraborty, and D. Haldar. 2005. Phosphorylation of rat liver mitochondrial glycerol-3-phosphate acyltransferase by casein kinase 2. J. Biol. Chem. 280: 19527-19534.
    • (2005) J. Biol. Chem , vol.280 , pp. 19527-19534
    • Onorato, T.M.1    Chakraborty, S.2    Haldar, D.3
  • 59
    • 38049030169 scopus 로고    scopus 로고
    • Acute effects of insulin on the activity of mitochondrial GPAT1 in primary adipocytes
    • Bronnikov, G. E., N. Aboulaich, A. V. Vener, and P. Stralfors. 2008. Acute effects of insulin on the activity of mitochondrial GPAT1 in primary adipocytes. Biochem. Biophys. Res. Commun. 367: 201-207.
    • (2008) Biochem. Biophys. Res. Commun , vol.367 , pp. 201-207
    • Bronnikov, G.E.1    Aboulaich, N.2    Vener, A.V.3    Stralfors, P.4
  • 62
    • 27244440736 scopus 로고    scopus 로고
    • Prevention of hepatic steatosis and hepatic insulin resistance in mitochondrial acyl-CoA:glycerol-sn-3-phosphate acyltransferase 1 knockout mice
    • Neschen, S., K. Morino, L. E. Hammond, D. Zhang, Z. X. Liu, A. J. Romanelli, G. W. Cline, R. L. Pongratz, X. M. Zhang, C. S. Choi, et al. 2005. Prevention of hepatic steatosis and hepatic insulin resistance in mitochondrial acyl-CoA:glycerol-sn-3-phosphate acyltransferase 1 knockout mice. Cell Metab. 2: 55-65.
    • (2005) Cell Metab , vol.2 , pp. 55-65
    • Neschen, S.1    Morino, K.2    Hammond, L.E.3    Zhang, D.4    Liu, Z.X.5    Romanelli, A.J.6    Cline, G.W.7    Pongratz, R.L.8    Zhang, X.M.9    Choi, C.S.10
  • 64
    • 33645820583 scopus 로고    scopus 로고
    • Liver-directed overexpression of mitochondrial glycerol-3-phosphate acyltransferase results in hepatic steatosis, increased triacylglycerol secretion and reduced fatty acid oxidation
    • Linden, D., L. William-Olsson, A. Ahnmark, K. Ekroos, C. Hallberg, H. P. Sjogren, B. Becker, L. Svensson, J. C. Clapham, J. Oscarsson, et al. 2006. Liver-directed overexpression of mitochondrial glycerol-3-phosphate acyltransferase results in hepatic steatosis, increased triacylglycerol secretion and reduced fatty acid oxidation. FASEB J. 20: 434-443.
    • (2006) FASEB J , vol.20 , pp. 434-443
    • Linden, D.1    William-Olsson, L.2    Ahnmark, A.3    Ekroos, K.4    Hallberg, C.5    Sjogren, H.P.6    Becker, B.7    Svensson, L.8    Clapham, J.C.9    Oscarsson, J.10
  • 66
    • 17444364801 scopus 로고    scopus 로고
    • Mitochondrial glycerol-3-phosphate acyltransferase-1 directs the metabolic fate of exogenous fatty acids in hepatocytes
    • Lewin, T.M., S. Wang, C. A. Nagle, C. G. VanHorn, and R. A.Coleman. 2005. Mitochondrial glycerol-3-phosphate acyltransferase-1 directs the metabolic fate of exogenous fatty acids in hepatocytes. Am. J. Physiol. Endocrinol. Metab. 288: E835-E844.
    • (2005) Am. J. Physiol. Endocrinol. Metab , vol.288
    • Lewin, T.M.1    Wang, S.2    Nagle, C.A.3    VanHorn, C.G.4    Coleman, R.A.5
  • 67
    • 33947726025 scopus 로고    scopus 로고
    • Increased oxidative stress is associated with balanced increases in hepatocyte apoptosis and proliferation in glycerol-3-phosphate acyltransferase-1 deficient mice
    • Hammond, L. E., C. D. Albright, L. He, I. Rusyn, S. M. Watkins, S. D. Doughman, J. J. Lemasters, and R. A. Coleman. 2007. Increased oxidative stress is associated with balanced increases in hepatocyte apoptosis and proliferation in glycerol-3-phosphate acyltransferase-1 deficient mice. Exp. Mol. Pathol. 82: 210-219.
    • (2007) Exp. Mol. Pathol , vol.82 , pp. 210-219
    • Hammond, L.E.1    Albright, C.D.2    He, L.3    Rusyn, I.4    Watkins, S.M.5    Doughman, S.D.6    Lemasters, J.J.7    Coleman, R.A.8
  • 70
    • 0018070301 scopus 로고
    • Rat adipose-tissue glycerol phosphate acyltransferase can be inactivated by cyclic AMP-dependent protein kinase
    • Nimmo, H. G., and B. Houston. 1978. Rat adipose-tissue glycerol phosphate acyltransferase can be inactivated by cyclic AMP-dependent protein kinase. Biochem. J. 176: 607-610.
    • (1978) Biochem. J , vol.176 , pp. 607-610
    • Nimmo, H.G.1    Houston, B.2
  • 71
    • 44949176737 scopus 로고    scopus 로고
    • Identification of a novel sn-glycerol-3-phosphate acyltransferase isoform, GPAT4, as the enzyme deficient in Agpat-/- mice
    • Nagle, C. A., L. Vergnes, H. Dejong, S. Wang, T. M. Lewin, K. Reue, and R. A. Coleman. 2008. Identification of a novel sn-glycerol-3-phosphate acyltransferase isoform, GPAT4, as the enzyme deficient in Agpat-/- mice. J. Lipid Res. 49: 823-831.
    • (2008) J. Lipid Res , vol.49 , pp. 823-831
    • Nagle, C.A.1    Vergnes, L.2    Dejong, H.3    Wang, S.4    Lewin, T.M.5    Reue, K.6    Coleman, R.A.7
  • 74
  • 75
    • 0033521142 scopus 로고    scopus 로고
    • A conserved seven amino acid stretch important for murine mitochondrial glycerol-3-phosphate acyltransferase activity. Significance of arginine 318 in catalysis
    • Dircks, L. K., J. Ke, and H. S. Sul. 1999. A conserved seven amino acid stretch important for murine mitochondrial glycerol-3-phosphate acyltransferase activity. Significance of arginine 318 in catalysis. J. Biol. Chem. 274: 34728-34734.
    • (1999) J. Biol. Chem , vol.274 , pp. 34728-34734
    • Dircks, L.K.1    Ke, J.2    Sul, H.S.3
  • 76
    • 0031941001 scopus 로고    scopus 로고
    • A conserved histidine is essential for glycerolipid acyltransferase catalysis
    • Heath, R. J., and C. O. Rock. 1998. A conserved histidine is essential for glycerolipid acyltransferase catalysis. J. Bacteriol. 180: 1425-1430.
    • (1998) J. Bacteriol , vol.180 , pp. 1425-1430
    • Heath, R.J.1    Rock, C.O.2
  • 77
    • 0033031797 scopus 로고    scopus 로고
    • A missense mutation accounts for the defect in the glycerol-3-phosphate acyltransferase expressed in the plsB26 mutant
    • Heath, R. J., and C. O. Rock. 1999. A missense mutation accounts for the defect in the glycerol-3-phosphate acyltransferase expressed in the plsB26 mutant. J. Bacteriol. 181: 1944-1946.
    • (1999) J. Bacteriol , vol.181 , pp. 1944-1946
    • Heath, R.J.1    Rock, C.O.2
  • 78
    • 0034644670 scopus 로고    scopus 로고
    • Identification of two transmembrane regions and a cytosolic domain of rat mitochondrial glycerophosphate acyltransferase
    • Balija, V. S., T. R. Chakraborty, A. V. Nikonov, T. Morimoto, and D. Haldar. 2000. Identification of two transmembrane regions and a cytosolic domain of rat mitochondrial glycerophosphate acyltransferase. J. Biol. Chem. 275: 31668-31673.
    • (2000) J. Biol. Chem , vol.275 , pp. 31668-31673
    • Balija, V.S.1    Chakraborty, T.R.2    Nikonov, A.V.3    Morimoto, T.4    Haldar, D.5
  • 79
    • 0035900732 scopus 로고    scopus 로고
    • Mitochondrial glycerol phosphate acyltransferase contains two transmembrane domains with the active site in the N-terminal domain facing the cytosol
    • Gonzalez-Baro, M. R., D. A. Granger, and R. A. Coleman. 2001. Mitochondrial glycerol phosphate acyltransferase contains two transmembrane domains with the active site in the N-terminal domain facing the cytosol. J. Biol. Chem. 276: 43182-43188.
    • (2001) J. Biol. Chem , vol.276 , pp. 43182-43188
    • Gonzalez-Baro, M.R.1    Granger, D.A.2    Coleman, R.A.3
  • 80
    • 0035834709 scopus 로고    scopus 로고
    • Mitochondrial glycerol phosphate acyltransferase directs the incorporation of exogenous fatty acids into triacylglycerol
    • Igal, R. A., S. Wang, M. Gonzalez-Baro, and R. A. Coleman. 2001. Mitochondrial glycerol phosphate acyltransferase directs the incorporation of exogenous fatty acids into triacylglycerol. J. Biol. Chem. 276: 42205-42212.
    • (2001) J. Biol. Chem , vol.276 , pp. 42205-42212
    • Igal, R.A.1    Wang, S.2    Gonzalez-Baro, M.3    Coleman, R.A.4
  • 81
    • 33750813851 scopus 로고    scopus 로고
    • Identification of a novel human lysophosphatidic acid acyltransferase, LPAAT-theta, which activates mTOR pathway
    • Tang, W., J. Yuan, X. Chen, X. Gu, K. Luo, J. Li, B. Wan, Y. Wang, and L. Yu. 2006. Identification of a novel human lysophosphatidic acid acyltransferase, LPAAT-theta, which activates mTOR pathway. J. Biochem. Mol. Biol. 39: 626-635.
    • (2006) J. Biochem. Mol. Biol , vol.39 , pp. 626-635
    • Tang, W.1    Yuan, J.2    Chen, X.3    Gu, X.4    Luo, K.5    Li, J.6    Wan, B.7    Wang, Y.8    Yu, L.9
  • 85
    • 0141644278 scopus 로고    scopus 로고
    • Cloning and identification of the human LPAAT-zeta gene, a novel member of the lysophosphatidic acid acyltransferase family
    • Li, D., L. Yu, H. Wu, Y. Shan, J. Guo, Y. Dang, Y. Wei, and S. Zhao. 2003. Cloning and identification of the human LPAAT-zeta gene, a novel member of the lysophosphatidic acid acyltransferase family. J. Hum. Genet. 48: 438-442.
    • (2003) J. Hum. Genet , vol.48 , pp. 438-442
    • Li, D.1    Yu, L.2    Wu, H.3    Shan, Y.4    Guo, J.5    Dang, Y.6    Wei, Y.7    Zhao, S.8
  • 86
    • 33646145315 scopus 로고    scopus 로고
    • Functional characterization of human 1-acylglycerol-3-phosphate acyltransferase isoform 8: Cloning, tissue distribution, gene structure, and enzymatic activity
    • Agarwal, A. K., R. I. Barnes, and A. Garg. 2006. Functional characterization of human 1-acylglycerol-3-phosphate acyltransferase isoform 8: cloning, tissue distribution, gene structure, and enzymatic activity. Arch. Biochem. Biophys. 449: 64-76.
    • (2006) Arch. Biochem. Biophys , vol.449 , pp. 64-76
    • Agarwal, A.K.1    Barnes, R.I.2    Garg, A.3
  • 87
    • 34447104351 scopus 로고    scopus 로고
    • Functional characterization of human 1-acylglycerol-3-phosphate-O-acyltransferase isoform 9: Cloning, tissue distribution, gene structure, and enzymatic activity
    • Agarwal, A. K., S. Sukumaran, R. Bartz, R. I. Barnes, and A. Garg. 2007. Functional characterization of human 1-acylglycerol-3-phosphate-O-acyltransferase isoform 9: cloning, tissue distribution, gene structure, and enzymatic activity. J. Endocrinol. 193: 445-457.
    • (2007) J. Endocrinol , vol.193 , pp. 445-457
    • Agarwal, A.K.1    Sukumaran, S.2    Bartz, R.3    Barnes, R.I.4    Garg, A.5
  • 88
    • 3843084029 scopus 로고    scopus 로고
    • A novel cardiolipin-remodeling pathway revealed by a gene encoding an endoplasmic reticulum-associated acyl-CoA:lysocardiolipin acyl-transferase (ALCAT1) in mouse
    • Cao, J., Y. Liu, J. Lockwood, P. Burn, and Y. Shi. 2004. A novel cardiolipin-remodeling pathway revealed by a gene encoding an endoplasmic reticulum-associated acyl-CoA:lysocardiolipin acyl-transferase (ALCAT1) in mouse. J. Biol. Chem. 279: 31727-31734.
    • (2004) J. Biol. Chem , vol.279 , pp. 31727-31734
    • Cao, J.1    Liu, Y.2    Lockwood, J.3    Burn, P.4    Shi, Y.5
  • 89
    • 33745976120 scopus 로고    scopus 로고
    • Cloning and characterization of mouse lung-type acyl-CoA:lysophosphatidylcholine acyltransferase 1 (LPCAT1). Expression in alveolar type II cells and possible involvement in surfactant production
    • Nakanishi, H., H. Shindou, D. Hishikawa, T. Harayama, R. Ogasawara, A. Suwabe, R. Taguchi, and T. Shimizu. 2006. Cloning and characterization of mouse lung-type acyl-CoA:lysophosphatidylcholine acyltransferase 1 (LPCAT1). Expression in alveolar type II cells and possible involvement in surfactant production. J. Biol. Chem. 281: 20140-20147.
    • (2006) J. Biol. Chem , vol.281 , pp. 20140-20147
    • Nakanishi, H.1    Shindou, H.2    Hishikawa, D.3    Harayama, T.4    Ogasawara, R.5    Suwabe, A.6    Taguchi, R.7    Shimizu, T.8


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