Regulation of hepatocyte lipid metabolism and inflammatory response by 25-hydroxycholesterol and 25-hydroxycholesterol-3-sulfate

Lipids

Volumn 45, Issue 9, 2010, Pages 821-832

  Xu, Leyuan ^a   Bai, Qianming ^a   Rodriguez Agudo, Daniel ^a   Hylemon, Phillip B ^b   Heuman, Douglas M ^a   Pandak, William M ^a   Ren, Shunlin ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

Author keywords

I B ; Inflammatory response; Lipid metabolism; LXR; NF B; Nuclear orphan receptor; Oxysterol metabolism; Oxysterol sulfation

Indexed keywords

25 HYDROXYCHOLESTEROL; 25 HYDROXYCHOLESTEROL 3 SULFATE; ACETYL COENZYME A CARBOXYLASE; CHOLESTEROL; FATTY ACID SYNTHASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; LIVER X RECEPTOR; LUCIFERASE; MESSENGER RNA; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; STEROL REGULATORY ELEMENT BINDING PROTEIN 2; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 1; UNCLASSIFIED DRUG;

ARTICLE; CHOLESTEROL SYNTHESIS; CYTOPLASM; DOWN REGULATION; ENZYME ACTIVATION; ENZYME INHIBITION; FATTY ACID SYNTHESIS; GENE EXPRESSION; GENE TARGETING; INFLAMMATION; LIPID METABOLISM; LIVER CELL; METABOLIC REGULATION; PROMOTER REGION; SIGNAL TRANSDUCTION;

ANIMALS; CHOLESTEROL ESTERS; DOSE-RESPONSE RELATIONSHIP, DRUG; HEPATOCYTES; HYDROXYCHOLESTEROLS; INFLAMMATION MEDIATORS; LIPID METABOLISM; LIVER; PROTEIN-SERINE-THREONINE KINASES; RATS; RECEPTORS, RETINOIC ACID; RNA, MESSENGER; STEROL REGULATORY ELEMENT BINDING PROTEIN 1;

RATTUS;

EID: 77957558615     PISSN: 00244201     EISSN: 15589307     Source Type: Journal    
DOI: 10.1007/s11745-010-3451-y     Document Type: Article

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