Salt-inducible kinase 2 links transcriptional coactivator p300 phosphorylation to the prevention of ChREBP-dependent hepatic steatosis in mice

Journal of Clinical Investigation

Volumn 120, Issue 12, 2010, Pages 4316-4331

  Bricambert, Julien ^a,b   Miranda, Jonatan ^a,b,c   Benhamed, Fadila ^a,b   Girard, Jean ^a,b   Postic, Catherine ^a,b   Dentin, Renaud ^a,b  

^a INSTITUT COCHIN   (France)

^b INSERM   (France)

^c UNIVERSITY OF THE BASQUE COUNTRY UPV EHU   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOHYDRATE RESPONSIVE ELEMENT BINDING PROTEIN; HISTONE ACETYLTRANSFERASE COACTIVATOR P300; LYSINE; PROTEIN SERINE THREONINE KINASE; SALT INDUCIBLE KINASE 2; SERINE; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ACETYLATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DNA BINDING; ENZYME ACTIVITY; ENZYME INHIBITION; FATTY ACID METABOLISM; FATTY ACID SYNTHESIS; FATTY LIVER; GLUCONEOGENESIS; GLUCOSE HOMEOSTASIS; GLUCOSE METABOLISM; HUMAN; HUMAN CELL; INFLAMMATION; INSULIN RESISTANCE; LIPID METABOLISM; LIPOGENESIS; LIVER CELL CULTURE; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROMOTER REGION; PROPHYLAXIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; TRANSCRIPTION INITIATION;

ACETYLATION; ANIMALS; BINDING SITES; CELLS, CULTURED; DISEASE MODELS, ANIMAL; FATTY ACIDS; FATTY LIVER; GENE KNOCKDOWN TECHNIQUES; HEPATOCYTES; HUMANS; INFLAMMATION; INSULIN RESISTANCE; MICE; MICE, TRANSGENIC; NUCLEAR PROTEINS; P300-CBP TRANSCRIPTION FACTORS; PHOSPHORYLATION; PROMOTER REGIONS, GENETIC; PROTEIN-SERINE-THREONINE KINASES; PYRUVATE KINASE; TRANSCRIPTION FACTORS;

EID: 78649855297     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI41624     Document Type: Article

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