Identification of 5α,6α-epoxycholesterol as a novel modulator of liver X receptor activity

Molecular Pharmacology

Volumn 78, Issue 6, 2010, Pages 1046-1058

  Berrodin, Thomas J ^a   Shen, Qi ^a   Quinet, Elaine M ^a   Yudt, Matthew R ^a   Freedman, Leonard P ^a,b   Nagpal, Sunil ^a  

^a PFIZER INC   (United States)

^b THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

22 HYDROXYCHOLESTEROL; 25 HYDROXYCHOLESTEROL; 26 HYDROXYCHOLESTEROL; 5 ALPHA 6 ALPHA EPOXYCHOLESTEROL; CELL NUCLEUS RECEPTOR; LIGAND; LIPID; LIVER X RECEPTOR; LIVER X RECEPTOR ALPHA; LIVER X RECEPTOR BETA; OXYSTEROL; PEPTIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; ATHEROSCLEROTIC PLAQUE; BIOCHEMISTRY; BIOLOGICAL PHENOMENA AND FUNCTIONS CONCERNING THE ENTIRE ORGANISM; CELL ASSAY; CELL DIFFERENTIATION; FOOD; GENE EXPRESSION; HOMEOSTASIS; HUMAN; HUMAN CELL; ISOTOPE LABELING; KERATINOCYTE; LIPID METABOLISM; LIVER; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; CELL LINE, TUMOR; CELLS, CULTURED; CHOLESTEROL; HUMANS; MICE; MICE, 129 STRAIN; MICE, INBRED C57BL; MICE, KNOCKOUT; ORPHAN NUCLEAR RECEPTORS; PROTEIN BINDING; PROTEIN TRANSPORT;

EID: 78649944880     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.110.065193     Document Type: Article

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